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Annual Lecture in Structural Biology by Jennifer Lippincott-Schwartz


Jennifer Lippincott-Schwartz will give the lecture entitled ‘Emerging imaging technologies to study cell architecture, dynamics and function’ on Thursday 20th August 2020 at 4.00pm in the Biomedicum Eva & Georg Klein hall.

The annual SciLifeLab lecture series is set up in the recognition of the structural biology field and delivered by eminent scientists. It is open to anyone. A holder of the lectureship particularly spends time with students and postdocs. Jennifer will also give an account of her career path and discuss with students and postdocs at 09.30am in the SciLifeLab Air & Fire auditorium.

About Jennifer Lippincott-Schwartz

Research in Lippincott-Schwartz’s lab is aimed at developing live cell imaging to elucidate the dynamics inside eukaryotic cells. She pioneered photobleaching and photoactivation techniques, which allow investigation of subcellular localization, turnover and trafficking of proteins, and compartmentalization. Her work on photoactivatable GFP led also to the development of one of the first super-resolution imaging technologies, photoactivation localization microscopy (PALM). She then used the methods to assess organelle dynamics and interactions revealing how the peripheral endoplasmic reticulum is structured. The Golgi apparatus is also central to Lippincott-Schwartz’s research, and her lab demonstrated a pathway of enzyme recycling important for the organelle’s biogenesis and maintenance. Together, the obtained findings have provided insights into how genetic diseases affect proteins that help shape the endoplasmic reticulum.
In 2016, Lippincott-Schwartz initiated the Neuronal Cell Biology Program at Janelia. She is Fellow of the American Academy of Arts and Sciences Fellow, and also Honorary Fellow of the Royal Microscopical Society.

 

Background information

The annual lecture in structural biology is named in honour of Fritiof Sjöstrand, who pioneered the electron microscopy in Sweden in the 1950’s.

Sjöstrand studied medicine in Karolisnka Institute and became engaged in research on biological applications of electron microscopy. In 1943 he recorded skeletal muscle fibres for the first time. In the early 1950’s Sjöstrand developed an advanced microtome for thin sectioning and by applying it for structural analysis of mitochondria produced another major breakthrough with the determination of the double membrane system. He then engineered a next generation of microtomes that became known as the “Sjöstrand Ultramicrotome”, and about 500 units were acquired by research institutes worldwide. Later he moved to UCLA and continued on mitochondrial membranes and retinal synapses. Fritiof Sjöstrand founded and was Editor in Chief of the Journal of Structural Biology for 33 years.

Contact

Alexey Amunts, amunts@scilifelab.se

Date and time

2020-08-20 16:00 –  17:00

Location

Biomedicum Eva & Georg Klein hall, Solnavägen 9, 171 65 Solna