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Science for Life seminar-Campus Solna, Lars Steinmetz, Developing technology for the future of precision health

Tuesday Mars 26 at 16:15

Prof. Lars M. Steinmetz

Stanford University, USA

Dr. Lars M. Steinmetz is a Professor of Genetics at Stanford University, Co-Director of the Stanford Genome Technology Center, and Senior Scientist at the European Molecular Biology Laboratory (EMBL). His laboratories have a strong track record in developing and applying cutting-edge experimental, statistical, and computational methods in genomics. Many of the technologies he has pioneered have since become gold standards that are widely applied by others, and have so far led to the founding of two health technology companies—Levitas, and Sophia Genetics.

Title of the talk- Developing technology for the future of precision health: Meeting the needs of a changing medical landscape

Medicine is no longer a one-size-fits-all system, and is quickly becoming personalized, predictive, and participative. To meet these changing needs, my lab develops and applies novel technologies for measuring and modifying biological systems across scales. With precision genome editing, we have measured the effects of perturbations in isolation to better understand their phenotypic consequences. In the context of rare genetic diseases, this has allowed us to identify a novel therapeutic strategy for patients genetically-predisposed to cardiomyopathy. To complement these genetic approaches, we have developed wearable multi-parametric biosensors and novel measurement devices, including a magnetic levitation device that is a low-cost, high-throughput solution for characterizing circulating tumor cells. Our MagLev device has successfully been applied towards detecting drug resistance, as well as resolving cells and molecules in bodily fluids/tissues. These technological breakthroughs will help build the high-precision and wellness-focused medicine of the future.

Host: Vicent Pelachano