Keystone Symposium


Understanding the Function of Human Genome Variation
Scientific Organizers: Kerstin Lindblad-Toh and Xavier Estivill

May 31 – June 4, 2016
Uppsala Konsert & Kongress, Uppsala, Sweden

The goal of this meeting is to bring together experts that may address important questions such as the function of noncoding variation, the connection between selection and disease, the diverse action of variants in different physiological and pathological scenarios, who develop and apply novel tools to connect genotype and phenotype both in disease and in an evolutionary context. By combining the diverse knowledge of many aspects of genomic analysis, we hope to bring out critical discussion and novel approaches to understanding human genome variation of crucial importance for the individualized genome analysis that precision medicine proposes. We are now entering the age of precision medicine with the capacity to analyze the genome of every subject, evaluating the functional consequences of variability and its interaction with the environment at different time-points in life.

Session Topics:

• Pleiotropy and Epistasis of Variants Involved in Disease
• Finding the Causative Variant(s)
• Connection between Selection and Disease
• Defining the Functional Elements in the Human Genome
• Human History, Migration and Evolution
• Selection and Population Genetics
• Complex Disease and Genetic Variation
• Structural Variation

More information, abstract submission and registration