NGI Seminar series: Epigenetics


The National Genomics Infrastructure (NGI) hosted by SciLifeLab is welcoming you to register for a half-day event given within the new NGI series of scientific symposia, this time solely focusing on Epigenetic research.

Next Generation Sequencing (NGS) and genotyping technologies can be used to study phenotypic trait variations that result from heritable changes in gene expression. These technologies, available at the National Genomic Infrastructure (NGI), have revolutionized epigenetic research by providing cost effective ways of high throughput whole-genome analysis.

The aim of this symposium is to provide researcher with information of the possibilities to do perform these type of analysis in Sweden but also to provide an inspiring environment where researchers within epigenetics can interact with their colleagues, listen to peer presentations covering a broad range of epigenetic analysis tools in different organisms, and meet experts from NGI.

We are glad to be able to announce a high-quality program with Elin Grundberg from McGill University, Canada as key note speaker.

Technologies covered at the seminar;

Illumina and Ion sequencing of chromatine immunoprecipitatated DNA and RNA (ChIP), sequencing of bisulfite converted DNA, targeted re-sequencing of methylated regions (e.g. MeDIP samples), single-molecule sequencing of native, PCR-free DNA by PacBio SMRT technology as well as studies of whole-genome methylation profiles by Illumina genotyping array technology. NGI personnel will provide information on all these applications during the first talk of the symposium.

Venue

Folkhälsomyndigheten
Foton Gard-aulan
Nobels väg 18, 171 65 Solna

Program

13:00    Welcoming remarks

13:05    Introduction to NGS and genotyping techniques

13:45    Keynote speaker: Elin Grundberg, McGill University, Canada
Capture the Human Epigenome by High-Throughput Sequencing Technologies for Insight Into Common Disease Risk

14:15    Coffee and poster session

14:40    Åsa Johansson, Uppsala University.
Variation in DNA methylation in a human population

15:00    Dominic Wright, Linköping Universitet
Mapping methylation and gene expression variation in the chicken

15:20    Christopher Wheat, Stockholm University
Patterns of methylation underlying aging in a butterfly

15:40    Karl Ekwall, Karolinska Institutet
Clinical epigenetics of acute myeloid leukemia – a combined epigenomics approach

16:00-17:00 Snacks and poster session

 

Program in PDF

Registration

The seminar is free of charge, but registration is binding. Registration deadline is October 23rd. Register here.

Poster

If you are interested in presenting a poster at the seminar, please provide title at time of registration. Please note that there is a late poster session after the seminar.

Organizer

NGI is a national core infrastructure hosted by SciLifeLab, comprising four collaborating NGS sequencing and genotyping platforms in Stockholm and Uppsala. It is the third largest sequencing infrastructure in Europe and it is based on support from the Swedish Research Council (VR), SciLifeLab, Knut and Alice Wallenberg Foundation as well as the host universities (KI, KTH, SU and UU). NGI provides the cutting edge sequencing and genotyping service to Swedish academia at fees that are heavily subsidised by its sponsors.

Key note speaker: Elin Grundberg

Elin Grundberg currently is an associated professor at McGill University in Montreal, Canada. After obtaining doctoral degree at Uppsala University she moved to pursue her scientific carrier at McGill University in Canada, and later jointly at Welcome Trust Sanger Institute and the King’s College in London, UK.

Her research focus on genome-wide transcriptional changes caused by environmental factors and their effect on human health, as well as associations of non-coding variations with human diseases. She is a co-author of several Nature Genetics, Nature and PLoS Genetics papers addressing the role of epigenetic changes on different aspects of human health. Several of her publications are based on genotyping, transcriptome and methylome analyses by means of both NGS and genotyping arrays.