SciLifeLab The Svedberg seminar series 2013-10-28
David Cano González
Institute of Biomedicine of Seville (IBiS), Endocrinology Unit, University Hospital Virgen del Rocío, Sevilla, Spain.
“Development of the innervation of the pancreas: Role of Glial cell line-derived neurotrophic factor”
Innervation of the mammalian pancreas is crucial for endocrine and exocrine function. The study of pancreatic innervation has recently gained renewed interest due to reports indicating that formation of endocrine insulin-producing beta-cells during embryonic development is controlled by neural stimuli. In this seminar, I will summarize our knowledge of the colonization of the pancreas by neural precursors and the cues that guide this process. I will discuss our lab’s work showing that glial cell line-derived neurotrophic factor GDNF is a key player in the development of pancreas innervation.
Host: Elena Kozlova