SciLifeLab Workshops: Drug Discovery

This is the fourth in a series of monthly workshops covering various research themes central for SciLifeLab. This workshop focuses on Drug Discovery.

Venue: Trippelrummet E10:1309, Navet, SciLifeLab, Uppsala Biomedical Centre, entrance C11

Bus transfer from Tomtebodavägen 23A, SciLifeLab Stockholm at 08.30 and back at 14.30

Lunch is included.

There will be ample time for discussions, as the aim is to stimulate collaborations.

Registration is now open. Registration will close November 27.



9.30-10.00 Coffee

10.00-10.05 – Welcome and Introduction
Helena Danielson, Professor, Platform Director SciLifeLab DDD Biophysical Screening and Characterization facility, Dept. of Chemistry, BMC, Uppsala University

10.05-10.45 – The application of Biophysical Methods in Drug Discovery
Matthias Frech, Director, Molecular Interactions & Biophysics, Merck Serono, Research and Development

10.45-11.00 – Break

11.00-11.40 – The rule of 5 and beyond – How can Medicinal Chemistry Expand the Druggable Genome?
Jan Kihlberg, Professor, Dept. of Chemistry, BMC, Uppsala University

11.40-12.20 – ADMET in Drug Discovery and Development
Ylva Terelius, PhD, Distinguished Scientist, Medivir AB, Huddinge

12.30-13.30 – Lunch

13.30-14.10 – Cellular Assays – Verifying Mechanism of Action, and Predicting Plasma Target Concentration
Vendela Parrow, PhD, Facility Manager, SciLifeLab DDD In vitro and systems Pharmacology facility, Dept. of Medical Sciences, Uppsala University


Suggested pre-workshop reading
1. Lessons learned from the fate of AstraZeneca’s drug pipeline: a five-dimensional framework.
Cook et al, Nat Rev Drug Discov. 2014 Jun;13(6):419-31. doi: 10.1038/nrd4309

2. Pharmacoeconomics and the medicinal chemist.
Lindsley CW. ACS Med Chem Lett. 2014 Sep 5;5(10):1066-8. doi: 10.1021/ml500351u. eCollection 2014


Organizer: Helena Danielson

For further information, please contact Eva Molin in Uppsala (