News - 2011


2011-12-22, NEWS

Genetic study of black chickens shed light on mechanisms causing rapid evolution in domestic animals

The genetic changes underlying the evolution of new species are still poorly understood. Genetic studies in domestic animals can shed light on this process due to the rapid evolution they have undergone over the last 10,000 years. A new study published today describes how a complex genomic rearrangement causes a fascinating phenotype in chickens.

2011-12-15, NEWS

Research strategies for Uppsala University 2013-2016

For more information in swedish: Research strategies for Uppsala University 2013-2016

2011-12-12, NEWS

Lars Rönnblom reveices grants from Ragnar Söderberg’s foundation

For more infomation in swedish: Lars Rönnblom reveices grants from Ragnar Söderberg’s foundation

2011-12-09, NEWS

Breakthrough in genetics of fibroids

Uterine leiomyomas, also called fibroids, cause a very significant burden to women’s health but relatively little has been known about the mechanisms of tumorigenesis involved. Researchers at the University of Helsinki and Karolinska Institutet have found specific mutations in a gene called MED12, which is an important step towards understanding why fibroids arise and how they can be treated.

2011-12-09, NEWS

Breakthrough in genetics of fibroids

Uterine leiomyomas, also called fibroids, cause a very significant burden to women’s health but relatively little has been known about the mechanisms of tumorigenesis involved. Researchers at the University of Helsinki and Karolinska Institutet have found specific mutations in a gene called MED12, which is an important step towards understanding why fibroids arise and how they can be treated.

2011-12-09, PRESS

A better way to count molecules discovered

Researchers at the Swedish medical university Karolinska Institutet have developed a new method for counting molecules. Quantifying the amounts of different kinds of RNA and DNA molecules is a fundamental task in molecular biology as these molecules store and transfer the genetic information in cells. Thus, improved measurement techniques are crucial for understanding both normal and cancer cells.

2011-12-08, NEWS

Siv Andersson recieves Wallenberg Scholars

For more infomation in swedish: Siv Andersson recieves Wallenberg Scholars

2011-12-07, NEWS

Ulf Landegren and Leif Andersson awarded ERC advanced grant

For more information in swedish: Ulf Landegren and Leif Andersson awarded ERC advanced grant

2011-12-01, NEWS

Orexo and Uppsala University Receive Swedish Research Council Grant for Bioceramics Project

For more information in swedish: Orexo and Uppsala University Receive Swedish Research Council Grant for Bioceramics Project

2011-11-28, PRESS

The proliferation of dingos and domesticated dogs in the world

For more information in Swedish

2011-11-28, PRESS

The wolf was tamed in Southeast asia

More infomation in Swedish

2011-11-22, NEWS

Ulf Landegren awarded”Björkénska priset”

For more information in swedish: Ulf Landegren awarded “Björkénska priset”

2011-11-17, NEWS

Kerstin Lindblad-Toh receives grants from Formas

For more information in swedish: Kerstin Lindblad-Toh receives grants from Formas

2011-11-16, NEWS

Tomas Axelsson receives grants from the Swedish Research Council; Research infrastructures

For more information in swedish: Tomas Axelsson receives grants from the Swedish Research Council; Research infrastructures

2011-11-06, NEWS

Lars Feuk: publication in Nature Structural and Moelcular Biology

For more information in swedish: Lars Feuk: publication in Nature Structural and Moelcular Biology

2011-11-02, PRESS

Gene switch important in cancer discovered

Scientists at Karolinska Institutet in Sweden and the University of Helsinki in Finland have shown that the “switches” that regulate the expression of genes play a major role in the development of cancer. In a study, published in Science, they have investigated a gene region that contains a particular single nucleotide variant associated with increased risk for developing colorectal and prostate cancers – and found that removing this region caused dramatic resistance to tumor formation.

2011-11-01, NEWS

Shared genes with Neanderthal relatives not unusual

During human evolution our ancestors mated with Neanderthals, but also with other related hominids. In this week’s online edition of PNAS, researchers from Uppsala University are publishing findings showing that people in East Asia share genetic material with Denisovans, who were named from the cave in Siberia where they were first found.

2011-10-12, NEWS

Millions of new regulatory elements found in human genome

An international research team led by Kerstin Lindblad-Toh at the Broad Institute, US and Uppsala University, Sweden has mapped and compared the genomes of 29 mammals. The findings, published in Nature, reveal millions of new regulatory elements in the human genome that in various ways govern how proteins are formed. The new knowledge is important for our understanding of how mutations in human genes give rise to diseases. The human genome was mapped some ten years ago, but its function has been difficult to understand. Recent comparisons with mice, rats, and dogs, have shown that humans have more than 20,000 genes. However, it has been difficult to find the elements in the genome that determine when, where, and how genes produce proteins.

2011-10-11, NEWS

SignalP 4.0: discriminating signal peptides from transmembrane regions

The secretory signal peptide is a ubiquitous protein- sorting signal that targets its passenger protein for translocation across the endoplasmic reticulum membrane in eukaryotes and the cytoplasmic membrane in prokaryotes.

2011-10-05, PRESS

New heredarity neurometabolic disease discovered

More information in Swedish

2011-10-05, NEWS

An algorithm for protein quantification by advanced peptide quality control

We present a tool to improve quantitative accuracy and precision in mass spectrometry based shotgun proteomics: protein quantification by peptide quality control, PQPQ. The method is based on the assumption that the quantitative pattern of peptides derived from one protein will correlate over several samples.

2011-10-03, NEWS

New version of FunCoup released (v2.0)

FunCoup is a database that maintains and visualises global gene/protein networks of functional coupling that have been constructed by Bayesian integration of diverse high-throughput data. FunCoup achieves high coverage by orthology-based integration of data sources from different model organisms and from different platforms.

2011-09-12, NEWS

Lars Feuk receives grants from the European Research Council

For more information in swedish: Disciplinary Domain of Medicine and Pharmacy: News

2011-09-01, PRESS

Lizard genome mapped for first time

Press release from Uppsala University Articles in DN SvD UNT NYHETERNA.SE

2011-08-31, PRESS

Lizard genome mapped for first time

A lizard genome has been mapped for the first time ever, by an international research team led by Kerstin Lindblad-Toh of the Broad Institute (U.S.) and Uppsala University. The findings, which have just been published in the scientific journal Nature, identify similarities and differences among lizards, birds and mammals and suggest that the ability of lizards to quickly adapt to new environments may depend on a dynamic genome.

2011-08-24, PRESS

Exciting discovery about the origin of humans

A major evolutionary biological study, performed partly by researchers at Uppsala University, reveals what has driven the evolution of new forms of life. The study also shows how such a complex life form as the human being could emerge. The findings are being published in the scientific journal Science.

2011-08-24, NEWS

Well visited SciLifeLab-DAY,

SciLifeLab Uppsala began the fall with the conference SciLifeLab-DAY. Approximately 230 scientists attended the conference, held twice a year for SciLifeLab members, one in January and one in August. The aim of SciLifeLab conferences is to build a strong community within life science research in Uppsala. Researchers in the community get the opportunity to meet and discuss both science and strategic perspectives.

2011-08-19, PRESS

Major advanced cancer study to be led by SciLifeLab

Several prominent cancer researchers are now joining forces in an advanced new cancer study. The goal is to understand which tumors will be difficult to treat and to find out why certain cancer drugs lose their effect after a period of use. The study is to be directed by Tobias Sjöblom, associate professor of tumor biology at Uppsala University, Sweden.

2011-08-18, PRESS

The SNP&SEQ-technical platform directed by Ann-Christine Syvänen contributes to the largest multiple sclerosis study ever undertaken.

Read scientific article

2011-07-05, PRESS

Publication in PNAS by Johan Elf

For more information in Swedish: Publication in PNAS by Johan Elf

2011-06-16, PRESS

SciLifeLab on Swedish Science Radio (Vetenskapsradion)

For more inforamtion in Swedish: SciLifeLab on Swedish Science Radio (Vetenskapsradion)

2011-06-14, PRESS

News from London: Exclusive Press Seminar on Stockholm-Uppsala-based Protein Research

The Swedish Embassy in London hosted a seminar for invited science journalists on May 13th 2011. The seminar, entitled ‘The age of protein science: hype or reality? Can it solve the world’s health problems?’, was organised by Stockholm-Uppsala Life Science (SULS). The invited panel members were experts on protein research from the region.

2011-06-14, PRESS

SciLifeLab members at AIMDay® Cancer

For more information in Swedish: SciLifeLab members at AIMDay® Cancer

2011-05-31, NEWS

New Publication by Marene Landström

Researchers in Uppsala and Umeå have found a new signaling pathway activated by TGFβ that makes tumor cells more aggressive. The study, led by the SciLifeLab member Marene Landström, might open new possibilities for early detection of aggressive prostate tumors and novel therapeutic strategies. The article was published in Nature Communications 31 May 2011

2011-05-25, NEWS

Clinical Genetics at SciLifeLab

How new technologies could be introduced into clinical practice and how data storage and safety can be dealt with was some of the topics of the Clinical Genetics Day, organised by SciLifeLab. Kerstin Lindblad-Toh, Director of SciLifeLab in Uppsala, opened the seminar.

2011-03-18, PRESS

Wrinkled dog is key to new direction within inflammation research

An international research team led from Uppsala University and the Broad Institute of MIT and Harvard has discovered the gene underlying the characteristic wrinkled skin of the Shar-Pei dog. The same gene has been shown to be associated with a chronic fever condition that often afflicts members of the breed. The findings, which are interesting from a human health standpoint, were published today in PLoS Genetics.

2011-03-14, NEWS

The SciLifeLab in Uppsala Genomics Platform participates in ESGI

The SciLifeLab in Uppsala Genomics Platform participates in the recently launched European Sequencing and Genotyping Infrastucture (ESGI) which provides transnational access to sequencing and genotyping. For more information, contact A-C Syvänen (Ann-Christine.Syvanen@medsci.uu.se). ESGI press release from 2011-03-14