New method provides better information on gene expression
A collaboration between professors Joakim Lundeberg, KTH Royal Institute of Technology/SciLifeLab and Jonas Frisén, Karolinsk Institutet, has resulted in a novel high-resolution method for studying which genes are active in a tissue. A great number of scientists connected to SciLifeLab also contributed to the article, which was are published in Science. The method can be used on all types of tissue and is valuable to both preclinical research and cancer diagnostics.
Visualization and analysis of gene expression in tissue sections by spatial transcriptomics
Patrik L. Ståhl, Fredrik Salmén, Sanja Vickovic, Anna Lundmark, José Fernández Navarro, Jens Magnusson, Stefania Giacomello, Michaela Asp, Jakub O. Westholm, Mikael Huss, Annelie Mollbrink, Sten Linnarsson, Simone Codeluppi, Åke Borg, Fredrik Pontén, Paul Igor Costea, Pelin Sahlén, Jan Mulder, Olaf Bergmann, Joakim Lundeberg, Jonas Frisén. Science, published online 1 July 2016, doi: 10.1126/science.aaf2403.