Researcher in Molecular in vitro Toxicology

Published: 2019-05-23


SciLifeLab, Department of Environmental Science and Analytical Chemistry, Stockholm University

Project description
We seek a researcher with strong skills in in vitro toxicology, or in a closely related research field, to study effects of real-world environmental chemical mixtures in cells. This will involve work with established cellular assays in multiwell format and development of new assays such as image-based  High Content Analysis (HCA) methods, to elucidate the health risk of environmental chemical mixtures found in individual human blood samples. The project will make effective use of existing infrastructure, including liquid handling robotics and High-Throughput Screening (HTS) technology, at SciLifeLab. The successful candidate will work as part of a bigger team involving toxicologists, analytical chemists, molecular biologists and bioinformaticians to understand the toxicological effects of environmental chemical mixtures in the human body.

Main responsibilities
The researcher will work in Professor Oskar Karlsson and Jonathan Martin research groups at SciLifeLab (Solna). The major objective will be to establish state-of-the art cellular assays to measure the cytotoxicity, epigenetic effects and endocrine disrupting potential of environmental chemical mixtures. The succesfull candidate will be expected to plan, conduct, interpret and communicate the research and results.

Qualification requirements
Researchers are appointed primarily for purposes of research and must hold a Swedish doctoral degree or an equivalent degree from another country.

Assessment criteria
In the appointment process, special attention will be given to research skills in in vitro toxicology and cell-based methods. Experience in mixture toxicology, molecular biology, HTS, high content cell imaging and analysis using software such as CellProfiler will be considered a great asset.

Terms of employment
The position involves full-time employment for a maximum of two years. Start date is suggested as September 2019, but is flexible.

Stockholm University strives to be a workplace free from discrimination and with equal opportunities for all.

Contact
Further information about the position can be obtained from Associate Professor Oskar Karlsson, oskar.karlsson@aces.su.se.

 

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