Master Programme in Molecular Medicine
The International Master program in Molecular Medicine at Uppsala University is strongly research oriented and focus on molecular mechanisms causing diseases, the use and applications of new technologies in genomics/epigenetics/proteomics as well as the development of prognostic, diagnostic and therapeutic tools.
The program is closely linked to current research activities at SciLifeLab, and most of affiliated scientists and experts in their field are teaching on the program. The master students often participate in international seminars and symposia at SciLifelab as well as undertake projects in different research groups. Most graduates of this program continue research studies as PhDs in different countries or in biotechnical or pharmaceutical industry.
During the master program, the students are trained in several techniques; e.g. STR genotyping, DNA methylation analysis, Chromatin immunoprecipitation analysis of histone modifications, Proximity Ligation Assay (PLA) in solution in situ, differentiation of stem cells and digital image analysis. The master program emphasizes also independent presentations in English, both written and oral, of the student’s own as well as published research data.
Short description of program courses
Medical genetics and cancer; molecular mechanisms (15 credits), describes human molecular genetics as well as the genetic/epigenetic, molecular and cellular mechanisms causing genetic diseases including cancer. The course discusses methods and techniques investigating genetic variations as well as current techniques used in research, diagnostics and treatment of genetic diseases and cancer. During the course, the students perform practical exercises in STR genotyping of DNA materials as well as a DNA methylation analysis of promoters in cancer cell lines using pyrosequencing.
Advanced Techniques in Molecular Medicine (15 credits), includes, apart from lectures and seminars, an independent short research project, which the student performs in a research group under supervision. The results from the research project are concluded by the student into a written scientific article as well as in a public research seminar at the end of the course.
Genomic and Epigenomic Medicine 15 credits, aims to provide an in-depth knowledge of genomics, epigenomics and comparative genomics, the current research and methods as well as its importance in human disease. In this course, the students perform a chromatin immunoprecipitation (ChIP), assessing a cancer drug’s effect on the epigenetic status at promoters and enhancers.
Molecular tools for Proteome Analysis and Diagnostics 7.5 credits and Biomarkers; discovery and validation, 7.5 credits, aim to provide an in-depth knowledge of molecular diagnostic methods and their use in research and medicine as well as an insight into the current knowledge, future potential use and development of biomarkers as both prognostic and diagnostic tools in health care. During these courses, the students perform Proximity Ligation Assay (PLA) both in solution and in situ as well as use the Human Proteome Atlas in a quest for novel biomarkers for different cancers and other diseases.
Bioimaging and Cell analysis 7.5 credits and Regenerative Medicine 7.5 credits, provide knowledge and practical experiences in digital image analysis, different microscopy techniques as well as tissue engineering, stem cell biology and differentiation. During the practical exercises she isolated and differentiate stem cells to neuronal cells, analysis stem cell markers by FACS analysis.
The final independent Master Degree project 30 c or 45 c is individually undertaken in research groups or industry, in Sweden or abroad.
For questions about the programme, please contact Lena Åslund