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DTSTART;TZID=Europe/Stockholm:20250612T150000
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DTSTAMP:20260308T084700
CREATED:20250609T042830Z
LAST-MODIFIED:20250609T043118Z
UID:186648-1749740400-1749744000@www.scilifelab.se
SUMMARY:Exploring the Protein Universe via Highly Accurate Structural Predictions
DESCRIPTION:Speaker\n\n\n\nMartin Steinegger\, Seoul National University \n\n\n\nAbstract\n\n\n\nUnderstanding relationships and functions of proteins at a global scale is key to unlocking newbiological insights. Through next-generation structure predictors like AlphaFold2 and ESMfold\,we now have access to an unprecedented volume of protein structures\, providing a crucialfoundation to address this challenge. In this talk\, I will present how our computationalmethods ColabFold\, MMseqs2\, and Foldseek together allow extraction of biological insightsfrom protein sequences and structures at nearly billion-scale. Additionally\, I will demonstratehow protein language models combined with sparse experimental data can guide andprioritize experimental efforts\, enabling efficient iterative “lab-in-the-loop” research.Together\, these tools democratize computational analysis and significantly acceleratediscoveries in protein biology.
URL:https://www.scilifelab.se/event/exploring-the-protein-universe-via-highly-accurate-structural-predictions/
LOCATION:Milkyway SciLifeLab Solna\, Tomtebodavägen 23\, Solna
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