Frances Arnold, California Institute of Technology, Pasadena, U.S.A.
Innovation by Evolution: Bringing New Chemistry to Life
Not satisfied with nature’s vast catalyst repertoire, I want to create new protein catalysts and expand the space of genetically encoded enzyme functions. We use the most powerful biological design process, evolution, to optimize existing enzymes and invent new ones, thereby circumventing our profound ignorance of how sequence encodes function. Using mechanistic understanding and mimicking nature’s evolutionary design processes, we have generated whole new families of ‘carbene transferases’ and ‘nitrene transferases’ that catalyze chemical reactions not previously known in biology. These capabilities increase the scope of molecules and materials we can build using synthetic biology and move us closer to a sustainable world where chemical synthesis can be fully programmed in DNA.
09:00 Coffee and mingle
09:30 Welcome & introduction to topic
09:40 Frances Arnold – Innovation by Evolution: Bringing New Chemistry to Life
10:20 Questions & Discussion
10:35 Coffee and mingle
Per-Olof Syrén, KTH/SciLifelab
Seats are limited and registration is mandatory.
Registration is now closed – the event is fully booked.
Necessary cookies are absolutely essential for the website to function properly. This category only includes cookies that ensures basic functionalities and security features of the website. These cookies do not store any personal information.
Any cookies that may not be particularly necessary for the website to function and is used specifically to collect user personal data via analytics, ads, other embedded contents are termed as non-necessary cookies. It is mandatory to procure user consent prior to running these cookies on your website.