Département de biologie & Département de biochimie, microbiologie and bio-informatique, Institut de biologie intégrative et des systems, Université Laval, Québec, Canada
Dr Christian Landry obtained his BSc and MSc degrees from Université Laval (1995-2000) where he worked on the evolution of MHC genes. He then trained as a PhD student at Harvard University (2001-2006) where he worked on the evolution of gene expression networks. He finally did a postdoctoral internship on the organization and evolution of protein interaction networks at Université de Montréal (2007-2009). Since 2009, he has been an independent investigator at Université Laval, first as a New Investigator of the Canadian Institute of Health Research (CIHR) and now as a Canada Research Chair in Evolutionary Cell and Systems Biology. Dr Landry has been elected as a member of the College of New Scholars, Artists and Scientists of the Royal Society of Canada and is currently a Steacie Memorial Fellow of the Natural Sciences and Engineering Research Council of Canada (NSERC).
The role of natural selection and other evolutionary forces in the evolution of complex traits has been extensively documented. However, we know very little on how the inner organization of cells respond to these driving forces. Also largely unknown is how the internal organization of the cell itself may affect the course of evolution, for instance in the recruitment of new genes. I will present our recent work on the evolution of protein interaction networks, including how gene duplication affects their organization and robustness. I will also discuss how the physical association of duplicated proteins may determine the potential for new genes to contribute to novel functions on the long term. Finally, I will discuss open questions in biology that require the combined approaches of evolutionary and cell biology to be fully answered at the mechanistic level.
Read more about Christian Landry´s research
Host: Anne-Marie Dion-Cote (firstname.lastname@example.org)
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