Tuesday, November 3, 2020 zoom meeting
SciLifeLab Fellow, CBH-Department of Protein Science, Systems Biology group, SciLifeLab
Dr. Saeed Shoaie is systems biologist, works in the area of host-microbiome interactions and graduated from Chalmers University of Technology. His lab aims are to develop systems biology approaches to understand the underlying mechanisms of human oral and gut microbiome actions in diseases and discover novel microbiome-derived treatments.
The human microbiome is a diverse and complex ecosystem integral for healthy human development. Recent advances in next-generation sequencing technology have paved the way for a ‘multi-omics’ era of microbiome research, uncovering associations between microbial dysbiosis and disease. Our ability to harness the full potential of these ‘multi-omics’ datasets are currently constrained by several technical, analytical, computational and bioinformatics factors. Thus, the question arises – can systems biology approaches pave the way to a new era in microbiome research; determining underlying mechanisms in health and disease, and identifying key microbial interactions and causalities? In this seminar, examples of developing new tools, microbial gene catalogues and implementing systems biology on human oral and gut microbiome will be discussed and how the outcomes could lead to overcome the paucity in the understanding of the mechanisms underpinning the host-microbiome interactions and pave the way for discovering new microbiome-derived therapies.
Host: Peter Nilsson
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