BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//SciLifeLab - ECPv6.16.2//NONSGML v1.0//EN
CALSCALE:GREGORIAN
METHOD:PUBLISH
X-WR-CALNAME:SciLifeLab
X-ORIGINAL-URL:https://www.scilifelab.se
X-WR-CALDESC:Events for SciLifeLab
REFRESH-INTERVAL;VALUE=DURATION:PT1H
X-Robots-Tag:noindex
X-PUBLISHED-TTL:PT1H
BEGIN:VTIMEZONE
TZID:Europe/Stockholm
BEGIN:DAYLIGHT
TZOFFSETFROM:+0100
TZOFFSETTO:+0200
TZNAME:CEST
DTSTART:20220327T010000
END:DAYLIGHT
BEGIN:STANDARD
TZOFFSETFROM:+0200
TZOFFSETTO:+0100
TZNAME:CET
DTSTART:20221030T010000
END:STANDARD
BEGIN:DAYLIGHT
TZOFFSETFROM:+0100
TZOFFSETTO:+0200
TZNAME:CEST
DTSTART:20230326T010000
END:DAYLIGHT
BEGIN:STANDARD
TZOFFSETFROM:+0200
TZOFFSETTO:+0100
TZNAME:CET
DTSTART:20231029T010000
END:STANDARD
BEGIN:DAYLIGHT
TZOFFSETFROM:+0100
TZOFFSETTO:+0200
TZNAME:CEST
DTSTART:20240331T010000
END:DAYLIGHT
BEGIN:STANDARD
TZOFFSETFROM:+0200
TZOFFSETTO:+0100
TZNAME:CET
DTSTART:20241027T010000
END:STANDARD
END:VTIMEZONE
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20231006T153000
DTEND;TZID=Europe/Stockholm:20231006T163000
DTSTAMP:20260610T100651
CREATED:20231002T160445Z
LAST-MODIFIED:20231002T160654Z
UID:157082-1696606200-1696609800@www.scilifelab.se
SUMMARY:Seminar "Stereo-Seq to study the brain gene expression across species" - Prof. Wei-Wu
DESCRIPTION:Speaker: Prof. Wei-Wu\n\n\n\nTitle of Talk: Stereo-Seq to study the brain gene expression across species\n\n\n\nThe whole-brain single-cell spatial transcriptome atlas and cross-species comparisonThe brain is the most complex organ of humans with the highest heterogeneity of cell types. The composition and spatial location of different neuron subtypes\, as well as their precise connections\, are the basis for brain functions. Rapid advances in spatial transcriptomic technologies allow spatial mapping of gene expression as well as cellular subtypes at single-cell resolution of brain sections. We applied Stereo-Seq technology developed by BGI\, to construct the whole-brain cell atlas for macaques\, marmoset\, and mice\, with hundreds of coronal slices of spatial transcriptome across the whole brain per animal. Single-cell spatial transcriptome reveals cell-type organization in the macaque cortex and cross-species comparative analysis identified primate-specific cell types enriched in cortical layer 4\, whose marker genes are expressed in a region-dependent manner (Chen et al.\, Cell 2023). Whole-brain cell atlas provides the cellular and molecular basis for understanding the function\, evolution\, development\, aging\, and pathogenesis of the brain. \n\n\n\nHost: Vicent Pelechano & Claudia Kutter
URL:https://www.scilifelab.se/event/seminar-stereo-seq-to-study-the-brain-gene-expression-across-species-prof-wei-wu/
LOCATION:Gamma 2 Lunchroom\, SciLifeLab\, Tomtebodavägen 23\, Solna\, Sweden
CATEGORIES:Community
ORGANIZER;CN="SciLifeLab Solna PhD & Postdoc Council":MAILTO:phd-council@scilifelab.se
END:VEVENT
END:VCALENDAR