Structural biology aims direct visualization of macromolecules and therefore provides the most definitive way to describe its mechanisms of action. High resolution cryo-electron microscopy (cryo-EM) is emerging and developing technique in structural biology capable of producing density maps for direct atomic modelling.
We gather a discussion group to better understand what is the current practice of cryo-EM, critically assess where it falls short, present the most recent developments and applications to interesting biological problems. We encourage everyone to take active part.
Cryo-EM structures of Tau filaments from Alzheimer’s disease brain: implications for fibril propagation arising from patient-based structural biology30 November, 09.30Venue: Gamma-5 Becquerel room
Speaker: Anthony Fitzpatrick, Biochemistry & Molecular Biophysics, Columbia University, New York, USA
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