BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//SciLifeLab - ECPv6.15.20//NONSGML v1.0//EN
CALSCALE:GREGORIAN
METHOD:PUBLISH
X-WR-CALNAME:SciLifeLab
X-ORIGINAL-URL:https://www.scilifelab.se
X-WR-CALDESC:Events for SciLifeLab
REFRESH-INTERVAL;VALUE=DURATION:PT1H
X-Robots-Tag:noindex
X-PUBLISHED-TTL:PT1H
BEGIN:VTIMEZONE
TZID:Europe/Stockholm
BEGIN:DAYLIGHT
TZOFFSETFROM:+0100
TZOFFSETTO:+0200
TZNAME:CEST
DTSTART:20250330T010000
END:DAYLIGHT
BEGIN:STANDARD
TZOFFSETFROM:+0200
TZOFFSETTO:+0100
TZNAME:CET
DTSTART:20251026T010000
END:STANDARD
BEGIN:DAYLIGHT
TZOFFSETFROM:+0100
TZOFFSETTO:+0200
TZNAME:CEST
DTSTART:20260329T010000
END:DAYLIGHT
BEGIN:STANDARD
TZOFFSETFROM:+0200
TZOFFSETTO:+0100
TZNAME:CET
DTSTART:20261025T010000
END:STANDARD
BEGIN:DAYLIGHT
TZOFFSETFROM:+0100
TZOFFSETTO:+0200
TZNAME:CEST
DTSTART:20270328T010000
END:DAYLIGHT
BEGIN:STANDARD
TZOFFSETFROM:+0200
TZOFFSETTO:+0100
TZNAME:CET
DTSTART:20271031T010000
END:STANDARD
END:VTIMEZONE
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20260216T140000
DTEND;TZID=Europe/Stockholm:20260216T150000
DTSTAMP:20260511T004042
CREATED:20260127T165907Z
LAST-MODIFIED:20260127T165952Z
UID:193909-1771250400-1771254000@www.scilifelab.se
SUMMARY:[The Svedberg seminar] - Super-resolution imaging of chromatin in health and disease
DESCRIPTION:Melike Lakadamyali \n\n\n\nProfessor University of Pennsylvania\, USA \n\n\n\n\n\n\n\nBio\n\n\n\nDr. Lakadamyali obtained her BS in Physics in 2001 from the University of Texas\, Austin and her PhD in Physics in 2006 from Harvard University. Dr. Lakadamyali started her independent group at ICFO-Institute of Photonic Sciences in Barcelona in 2010 and was awarded tenure in 2015. In 2017 she moved to the University of Pennsylvania´s Department of Physiology at the Perelman School of Medicine as an Assistant Professor\, was promoted to Associate Professor in 2020 and Full Professor in 2024. \n\n\n\nSuper-resolution imaging of chromatin in health and disease\n\n\n\nSuper-resolution microscopy has opened new possibilities for visualizing chromatin architecture in situ at nanoscale resolution. Leveraging quantitative super-resolution imaging\, we revealed the heterogeneous nature of nucleosome folding and demonstrated that chromatin structure at both nano- and meso-scales is highly plastic\, dynamically remodeling in response to chemical and mechanical cues in health and disease. By combining biologically interpretable feature extraction with machine learning\, we further showed that cells can be accurately classified into distinct states based solely on their multi-scale chromatin organization\, while also identifying the specific chromatin features that drive classification\, thus offering mechanistic insight into cell-state regulation. \n\n\n\n\n\n\n\nHost: Sebastian Deindl sebastian.deindl@icm.uu.se\, UU
URL:https://www.scilifelab.se/event/the-svedberg-seminar-melike-lakadamyali/
LOCATION:BMC Trippelrummet\, Husargatan 3\, entrance C11\, Uppsala\, Sweden
CATEGORIES:Event
ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2022/02/Picture1-The-Svedberg.png
ORGANIZER;CN="The Svedberg Seminar Series":MAILTO:thesvedberg@scilifelab.uu.se
END:VEVENT
END:VCALENDAR