Date: June 11, 09:00
Venue: Zoom, register below to receive link
State-of-the-art tissue clearing methods provide unprecedented, high-quality optical access to very large biological specimens from individual organs to entire intact animals. When combined with light-sheet microscopy and image informatics, currently available tissue- clearing methods including a hydrophilic tissue clearing method CUBIC, allows us to perform whole-brain and whole-body imaging with sub-cellular resolution. In addition, delipidation of biological specimens by tissue-clearing methods enables whole-organ staining with specific antibodies, which can be applied even to human biology and pathology. When combined with tissue clearing, these labelling methods allow us to systematically extract structural and functional information of complex mammalian organs. In this talk, I will discuss how tissue-clearing and its related technologies have been successfully integrated to create new biological insights and provide a perspective for future opportunities in biology and medicine.
Necessary cookies are absolutely essential for the website to function properly. This category only includes cookies that ensures basic functionalities and security features of the website. These cookies do not store any personal information.
Any cookies that may not be particularly necessary for the website to function and is used specifically to collect user personal data via analytics, ads, other embedded contents are termed as non-necessary cookies. It is mandatory to procure user consent prior to running these cookies on your website.