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X-WR-CALDESC:Events for SciLifeLab
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DTSTART;TZID=Europe/Stockholm:20240815T110000
DTEND;TZID=Europe/Stockholm:20240815T114500
DTSTAMP:20260422T235802
CREATED:20240624T140804Z
LAST-MODIFIED:20240624T141010Z
UID:10001286-1723719600-1723722300@www.scilifelab.se
SUMMARY:Calls for new project support from  chemical biology and genome engineering platform and the drug discovery & development platform
DESCRIPTION:The Chemical Biology and Genome Engineering platform and the Drug discovery and development (DDD) platform at SciLifeLab have calls out for projects support. \n\n\n\nThe Chemical Biology unit looks projects proposals including including assay development\, small molecule screening\, drug profiling\, and medicinal and computational chemistry.  For more information\, please visit www.cbcs.se. \n\n\n\nThe Chemical Biology and Genome Engineering platform are inviting project proposals aiming to explore compounds/drugs mechanism of action that harness the combined strengths of at least two platform units. If approved\, these projects will gain cost-effective access to CBGE’s cutting-edge technologies \n\n\n\nBoth the above welcome proposals in all areas of biology not only in human health. \n\n\n\nThe DDD platform has a call looking for new project proposals for drug discovery. All therapeutic modalities that can be developed in collaboration with the DDD platform at SciLifeLab are of interest\, including small molecules\, antibodies\, oligonucleotides and new modalities. \n\n\n\nSome users and projects are at the intersection between chemical biology and drug discoveryhttps://ki-se.zoom.us/j/61032835991 \n\n\n\nProgram: \n\n\n\n1. Presentation of CBGE offerings \n\n\n\n2. Presentation of the DDDp offerings \n\n\n\n3. Q/A
URL:https://www.scilifelab.se/event/calls-for-new-project-support-from-chemical-biology-and-genome-engineering-platform-and-the-drug-discovery-development-platform/
LOCATION:Online event via Zoom
CATEGORIES:Event
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BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20240816T100000
DTEND;TZID=Europe/Stockholm:20240816T110000
DTSTAMP:20260422T235802
CREATED:20240815T084917Z
LAST-MODIFIED:20240815T085734Z
UID:10001320-1723802400-1723806000@www.scilifelab.se
SUMMARY:The protein structure prediction problem: from Anfinsen's hypothesis to AlphaFold and beyond
DESCRIPTION:Claudio Mirabello\, NBIS\, Linköping University \n\n\n\nAbstract: Proteins are the tools responsible for most essential functions carried in every organism\, from viruses to mammals. In order to better understand the way a protein works\, it is important to know its three-dimensional structure. In the past few years\, new Machine Learning technologies – neural networks not too dissimilar to those powering ChatGPT – have made it possible to greatly accelerate the process of determination of protein structures by leveraging their evolutionary history. But how do these new technologies work\, how did we get to build tools such as AlphaFold and what comes next? \n\n\n\nNBIS arranges an open AI and IO Seminar Series aimed at knowledge-sharing about Artificial Intelligence and Integrative Omics (AI & IO) analysis and applications in the Life Science community. The seminar series is open to everyone. The seminar is run over Zoom on the third Friday of the month during academic terms\, typically between 10 and 11 am\, with approx. 45 min long presentation and 15 min discussion.
URL:https://www.scilifelab.se/event/the-protein-structure-prediction-problem-from-anfinsens-hypothesis-to-alphafold-and-beyond/
LOCATION:Online event via Zoom
CATEGORIES:Event
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20240822T150000
DTEND;TZID=Europe/Stockholm:20240822T160000
DTSTAMP:20260422T235802
CREATED:20240816T140228Z
LAST-MODIFIED:20240816T140230Z
UID:10001330-1724338800-1724342400@www.scilifelab.se
SUMMARY:A tale of two T cells - revealing the innate program of CD8+ T cells by single-cell genomics
DESCRIPTION:Dr. Andrew Grimson\, Cornell University CD8+ T cells are classically recognized as adaptive immune cells based on their ability to recognize specific foreign antigens via their T cell receptor (TCR). However\, recent studies indicate that some naive CD8+ T cells can respond to innate cytokines alone in the absence of TCR stimulation\, a phenomenon referred to as bystander activation. Here\, we demonstrate that neonatal CD8+ T cells undergo a robust and diverse program of bystander activation\, which can protect against bacterial\, viral\, and parasitic pathogens in a TCR-independent manner. Using a multi-omics approach\, we found that the innate-like bystander program of neonatal CD8+ T cells is mediated by rapid chromatin remodeling and controlled by a balance of Bach2 and AP-1 transcription factor activity. The innate CD8+ T cell subset that predominates in early life is also present in adult mice and humans\, indicating that multiple layers of defense exist within the adult naïve T cell pool\, a compartment that is more functionally diverse than previously thought. \n\n\n\nBiography \n\n\n\nThe Grimson laboratory investigates gene regulation\, with an emphasis on genomics and gene regulation. It has three areas of emphasis: first\, the application and development of genomics tools\, focusing on the immune system\, second\, the function of small RNA regulatory molecules (chiefly microRNAs\, focusing on their roles in the immune system)\, and third\, the identification and characterization of novel cis- regulatory elements within mRNAs\, and the impact such elements have on regulation of the transcriptome. These research areas represent Andrews long-standing experience and interest in the control of gene expression. As a graduate student\, Andrew investigated the NMD mRNA decay pathway (nonsense-mediated mRNA decay; Anderson lab\, University of Wisconsin-Madison)\, and as a postdoctoral fellow\, he focused on microRNA target prediction and small RNA evolution (Bartel lab\, Whitehead/MIT). In his laboratory at Cornell University\, their work typically combines high-throughput experimental and computational genomics\, together with traditional experimental approaches. Ongoing projects include both fundamental studies in post-transcriptional regulation\, for example: mechanistic characterization of novel regulatory pathways they have found; together with investigations into biological roles for post-transcriptional regulation\, for example: investigating roles for small RNAs in the mammalian immune system. A recurring theme in their work is understanding the mechanisms and consequences of regulation of the transcriptome; over the past five years\, almost all their work in this area has focused on the immune system. Moreover\, several of their previous and current projects leverage single-cell genomics technologies as a primary tool to study immune cell subsets. It is this theme – the interface of genomics and immunology – which is reflected in his role as mentor and sponsor for Connor Kean.
URL:https://www.scilifelab.se/event/a-tale-of-two-t-cells-revealing-the-innate-program-of-cd8-t-cells-by-single-cell-genomics/
LOCATION:Air&Fire\, SciLifeLab Stockholm\, Tomtebodavägen 23A\, Solna\, Sweden
CATEGORIES:Event
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BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20240829T090000
DTEND;TZID=Europe/Stockholm:20240830T170000
DTSTAMP:20260422T235802
CREATED:20240529T151739Z
LAST-MODIFIED:20240715T101009Z
UID:10001271-1724922000-1725037200@www.scilifelab.se
SUMMARY:Sixth SWACCS Junior Academy Workshop (JAWS)
DESCRIPTION:JAWS is a workshop organized by the Swedish Academic Consortium on Chemical Safety (SWACCS)\, Stockholm University and Karolinska Institutet for PhD students\, master students\, postdocs and researchers working in all fields related to chemicals\, health and the environment. We’re offering exciting presentations\, great networking opportunities\, and a workshop on how to write a press release for your own research. Also\, join us one day early (on August 28th) and be part of the SWACCS Regulatory Toxicology II course’s concept mapping workshop\, where you can learn more about the various kinds of scientific evidence being used by different organizations in society and how these sectors interact and collaborate with one another to reach the goal of a chemical safe future. \n\n\n\nContact \n\n\n\nSolveig Thielesolveig.thiele@scilifelab.se \n\n\n\n \n\n\n\nAugust 29 \n\n\n\n\nPresentations and perspectives on the topic “Can you be a scientist and an activist at the same time – how to reach out with your science in a non-academic way?”\n\n\n\nDinner (potential charge of 200 kr) \n\n\n\n\nAugust 30 \n\n\n\n\nWorkshop – “Reaching a broader audience with your research and learning how to write a press release.” Present and discuss your research with the other participants!\n\n\n\nMingle\n\n\n\n\nWe can only offer a limited number of spots\, so be quick to register. PhD students will be prioritized. Participants can earn credits for this workshop.
URL:https://www.scilifelab.se/event/sixth-swaccs-junior-academy-workshop-jaws/
LOCATION:Air&Fire\, SciLifeLab Stockholm\, Tomtebodavägen 23A\, Solna\, Sweden
CATEGORIES:Event
ORGANIZER;CN="Swedish Academic Consortium on Chemical Safety (SWACCS)":MAILTO:solveig.thiele@scilifelab.se
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BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20240829T110000
DTEND;TZID=Europe/Stockholm:20240830T134500
DTSTAMP:20260422T235802
CREATED:20240712T114659Z
LAST-MODIFIED:20240829T072610Z
UID:10001309-1724929200-1725025500@www.scilifelab.se
SUMMARY:Pandemic Laboratory Preparedness Retreat 2024
DESCRIPTION:The SciLifeLab Pandemic Laboratory Preparedness (PLP) program\, started in 2021\, acts to meet society’s need for efficient use of resources\, training and education\, to propagate skills and setting up technologies and equipment to be better equipped for new pandemics. \n\n\n\nThe PLP-retreat aims at strengthening the PLP network as well as an opportunity to highlight and discuss how the PLP program can evolve and be sustainable in the future. \n\n\n\nWith a poster session and focused group discussions on the key questions for pandemic preparedness\, we believe this will be a highly rewarding event for the participants\, and will spur many new ideas on how pandemic preparedness can be structured in the future.   For PLP members and collaborators onlyThe program below will be continuously uppdated  \n\n\n\nThursday\, August 29\n\n\n\n11:00Bus departure from SciLifeLab Uppsala/BMC Bus departure from SciLifeLab Solna Bus departure from Stockholm City Terminal (Gate 5)11:15Bus departure from Arlanda From outside terminal 4 (map)11:45LunchAronsborg12:30Plenary PresentationsStockholmsalenChair: Jessica Alm\, Karolinska Institutet12:30Welcome and Introduction Jessica Alm\, Karolinska Institutet12:40SciLifeLab Pandemic Laboratory Preparedness CapabilityStaffan Svärd\, Uppsala University13:00Evaluation of large-scale testing and contact tracing during the pandemic for better preparednessSara Byfors\, Swedish Public Health Agency13:20Short Break13:40Pandemic vaccination: how should we do it next time?Helena Hervius Askling\, Karolinska Institutet14:00Discussion: Prospective about MpoxSara Byfors\, Swedish Public Health AgencyHelena Hervius Askling\, Karolinska InstitutetAntonio Gigliotti Rothfuchs\, Karolinska Institutet14:20Preparedness for human biomonitoring – a toxicologists viewMattias Öberg\, Karolinska Institutet14:40Coffee Break15:10Flash TalksModerated by Peter Nilsson\, KTH16:20Who is the PLP master?Ulf Ribacke\, Karolinska Institutet16:50Concluding Remarks\, poster hanging and check-in to hotel18:00Mingle and Poster SessionUpplandssalen19:00Dinner21:00After Dinner MingleCrillo\n\n\n\n \n\n\n\n \n\n\n\nFriday\, August 30\n\n\n\n08:45Check out from hotel09:00Plenary PresentationsUpplandssalenChair: Staffan Svärd\, Uppsala University09:05What to expect when you’re not expectingBill Hanage\, Harvard University\, USA09:30Investigating the evolution of  panzootic H5N1 in mammalsThomas Peacock\, Pirbright Institute\, UK10:00Short Break10:15Pandrug-resistant gram-negative bacteria in Ukraine  – will they spread beyond hospitals?Kristian Riesbeck\, Lund University10:45Group Discussion IntroductionsStaffan Svärd\, Uppsala University10:50Coffee Break and Group Discussions12:00Group Discussion Summary in plenary; 1-2 min per groupModerator Staffan Svärd\, Uppsala University12:35Wrap-Up and taking down the posters12:40Bus Transfer to Arlanda Airport Brown paper bag-lunch to go.12:45Lunch13:45Bus Transfer to Stockholm City Terminal (via SciLifeLab Campus Solna) Bus Transfer to SciLifeLab Uppsala/BMC \n\n\n\n \n\n\n\n\n\nScientific Committee\n\n\n\nThe program has been developed by the Scientific committee.  \n\n\n\n\nStaffan Svärd\, PLP Scientific lead\, Uppsala University \n\n\n\nUlf Ribacke\, PLP Scientific co-lead\,  Karolinska Institutet & Uppsala University  \n\n\n\nJessica Alm\, Karolinska Institutet  \n\n\n\nPeter Nilsson\, KTH;\n\n\n\nDaniel Sheward\, Karolinska Institutet\n\n\n\nAlice Sollazzo\, Coordinator PLP-Program at SciLifeLab\, Alice.sollazzo@scilifelab.uu.se
URL:https://www.scilifelab.se/event/plp-retreat-2024/
LOCATION:Aronsborg Konferenshotell\, Helgövägen 7\, Bålsta\, 746 30
CATEGORIES:Event
ATTACH;FMTTYPE=image/jpeg:https://www.scilifelab.se/wp-content/uploads/2023/10/PLP_main.jpg
ORGANIZER;CN="Pandemic Laboratory Preparedness at SciLifeLab":MAILTO:alice.sollazzo@scilifelab.uu.se
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