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DTSTART;TZID=Europe/Stockholm:20210907T090000
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DTSTAMP:20260404T213918
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SUMMARY:BioImage Informatics Call4Help
DESCRIPTION:Every 1st week of the month (mainly on Tuesdays\, but there might be exceptions) the BioImage Informatics Facility together with microscopy expert Sylvie Le Guyader (LCI\, Karolinska Institutet) organizes a Call4Help session. The aim is to offer combined expertise towards microscopy and bioimage analysis. All researchers from Swedish institutes can participate. \n\n\n\nThe ideal timepoint to join the Call4Help session is when a researcher has performed pilot experiments and has tried out first analysis approaches – but before having recorded hundreds of images. Combining BIIF’s expertise in BioImage Analysis with microscopy expertise we can discuss ways to record the images that allow analysis afterwards. We will discuss different analysis approaches using mainly open-source software (Fiji\, CellProfiler\, QuPath\, Ilastik\, KNIME)\, but also commercial systems\, if needed (Imaris). \n\n\n\nThe Call4Help session format has been introduced to the BioImage Analysis community by NEUBIAS and ScopeM. \n\n\n\nHow to participate? \n\n\n\nStep1: \n\n\n\nPrepare a short presentation (5-7 min)  – use the following template for your presentation: \n\n\n\nhttp://bit.ly/BIIF_C4H_slideTemplate \n\n\n\nSlide template by NEUBIAS/ScopeM \n\n\n\nStep2: \n\n\n\na) Upload your presentation \n\n\n\nUpload your presentation to a drive of your choice. You can also use our Call4Help google drive. Note that files shared on our Call4Help drive will be available to everyone until the session is over. \n\n\n\nhttp://bit.ly/BIIF_C4H_Drive \n\n\n\nb) Upload example images for testing. \n\n\n\nUpload example images for testing either to the drive of your choice or our Call4Help google drive above. \n\n\n\nhttp://bit.ly/BIIF_C4H_Drive \n\n\n\nc) Register by filling out the registration form: \n\n\n\nhttp://bit.ly/BIIF_C4H_Registration \n\n\n\nStep 3: \n\n\n\nJoin the zoom-session. \n\n\n\nIf your problem is selected for presentation\, you will get a time-slot of 30 – 60 minutes within the session. \n\n\n\nWhat are the Deadlines \n\n\n\nSubmission of a problem and upload of example data: Friday the week before the session. \n\n\n\nNotification about participation: The day before the session. \n\n\n\nNext Call4Help session \n\n\n\nTuesday\, September 7\, 2021\, 9.00-11.00.  \n\n\n\nDeadline for application: Friday\, September 3\, 2021.
URL:https://www.scilifelab.se/event/bioimage-informatics-call4help-3/
CATEGORIES:Event
ORGANIZER;CN="Bioimage Informatics Unit":MAILTO:biif@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20210908T150000
DTEND;TZID=Europe/Stockholm:20210908T160000
DTSTAMP:20260404T213918
CREATED:20210827T090406Z
LAST-MODIFIED:20210902T144342Z
UID:10000416-1631113200-1631116800@www.scilifelab.se
SUMMARY:BiG Talks - Network based analysis of 1002 GWAS study defines a pleiotropy map of human cell biology
DESCRIPTION:BiG Talks: Integrative Omics\n\n\n\nArranged by the SciLifeLab platforms for Bioinformatics\, Genomics and Diagnostics Development \n\n\n\nThe Bioinformatics and Genomics seminar series (“BiG Talks”) is an initiative arranged by the SciLifeLab platforms for Bioinformatics (NBIS)\, Genomics (NGI) and Clinical Genomics platform. The seminar series aims to give inspiration to the SciLifeLab community and to create new networking possibilities. Each event will be broadcasted over Zoom where you will be able to interact with the speakers\, and live broadcasted at the SciLifeLab YouTube channel.  \n\n\n\nIn this seminar series\, run in parallel with the ELIXIR-SE / NBIS workshop in Omics Integration and Systems Biology\, we will be broadcasting three seminars about research and tools for integration of omics data through systems biology approaches\, in humans and model organisms. Please use the following link to register and access the Zoom link:  \n\n\n\nRegistration\n\n\n\n\n\n\n\n\n\n8th of September\, 15:00 – 16:00 CET \n\n\n\nNetwork based analysis of 1002 GWAS study defines a pleiotropy map of human cell biologyDr. Pedro BeltraoGroup Leader\, EMBL-EBI\, United Kingdom \n\n\n\nMore info\, see below \n\n\n\n \n\n\n\n\n\n10th of September\, 13:00 – 13:55 CET \n\n\n\nMetabolic Atlas: genome-scale metabolic models for easy browsing and analysisMihail AntonProject Manager for Metabolic Atlas\, NBIS / Chalmers University\, Sweden \n\n\n\nMore info \n\n\n\n\n\n10th of September\, 14:00 – 15:00 CET \n\n\n\nNetwork-based integration and visualization of large-scale dataDr. Lars Juhl JensenGroup Leader\, Novo Nordisk Foundation Center for Protein Research\, Denmark \n\n\n\nMore info \n\n\n\n\n\n\n\n\n\n\nNetwork based analysis of 1002 GWAS study defines a pleiotropy map of human cell biology\n\n\n\nDr. Pedro Beltrao\, Group Leader\, EMBL – EBI\, United Kingdom \n\n\n\nAbstract \n\n\n\nUnderstanding how genetic variation contributes to phenotypic differences is a central question in biology. This requires models that can describe how rare and common genetic variability impacts on different cellular components and traits. To study the impact of rare variants we develop and combine variant effect predictors for protein stability\, interaction affinity\, and gene expression regulation. We have applied these to study the impact of rare variants on trait variation in strains of micro-organisms\, including panels of 1000 strains of E. coli and S. cerevisiae.  For human we have used a network-based approach to study 1002 traits analysed by genome wide association studies (GWAS). Based on the principle that genes associated with the same phenotype tend to be involved in the same cellular processes\, we performed a network expansion and prioritization of trait associated genes. The network based gene-trait association scores allows for the identification of related traits and the biological processes that they share. Based on this we can identify pleiotropic biological processes that can influence a large number of human traits and identify opportunities for drug repurposing. Finally\, I will illustrate how this analysis can be combined with patient specific mRNA/protein data for further prioritization. I will focus on neurodegeneration diseases to illustrate the identification of shared aetiology and further integrate ALS SOD1 mutant patient mRNA/protein data to identify novel astrocyte candidate ALS linked genes. As a future perspective I will briefly discuss the need for approaches that can jointly integrate common and rare genetic variation to improve our understanding of trait variation. \n\n\n\nBiography \n\n\n\nDr. Pedro Beltrao is a group leader at EMBL – EBI where his research group seeks to understand how cellular functions have diverged during evolution as well as how they are altered in disease. He employs systems biology techniques to analyse GWAS\, post-translational modifications (PTMs) data from mass-spectrometry experiments\, among other omics\, to study the molecular sources of phenotypic novelties\, exploring how DNA changes are propagated through molecular structures and interaction networks to give rise to phenotypic variability. Dr. Beltrao has a PhD in Biology from the University of Aveiro (research conducted at EMBL-Heidelberg)\, after which he conducted his postdoctoral research at the University of California San Francisco. Dr. Beltrao is a group leader at EMBL-EBI since 2013\, and will join ETH Zurich in 2022.  Homepage: https://www.ebi.ac.uk/research-beta/beltrao/ \n\n\n\nHost: Rui Benfeitas\, NBIS Stockholm (rui.benfeitas@scilifelab.se) \n\n\n\nDate: September 8\, 15:00 – 16:00 CET online on Zoom \n\n\n\nBroadcast link (live event): SciLifeLab YouTube channel  \n\n\n\nRegistration form for zoom link
URL:https://www.scilifelab.se/event/big-talks-1/
LOCATION:Online event via Zoom
CATEGORIES:Event
ORGANIZER;CN="BiG Talks":MAILTO:info@nbis.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20210909T090000
DTEND;TZID=Europe/Stockholm:20210909T093000
DTSTAMP:20260404T213918
CREATED:20210830T154920Z
LAST-MODIFIED:20210903T142012Z
UID:10000421-1631178000-1631179800@www.scilifelab.se
SUMMARY:Clinical Talks: From BMC to Wall Street
DESCRIPTION:After our recent planning hiatus\, we now have the great pleasure to announce that “Clinical Talks” has been renewed for yet another exciting\, innovative\, and enlightening season. This season will focus on sustainable innovations within Life Sciences\, that have the potential to contribute to a better climate friendly future for our future generations. Also new this year is that the seminar is co-organized in a collaboration between SciLifeLab and KI Innovations. \n\n\n\nSeason 5\, will be held September until December 2021 with a total of seven scheduled Talks\, during Friday mornings 09-09:30 am via ZOOM (with some time-zone friendly adjustments for our international speakers). Each session consists of a talk given by our invited speaker followed by Q&A. The seminar is an open educational seminar series for our ever-expanding Life Science community. \n\n\n\nRead more about the clinical talk series here\n\n\n\n\n\n\n\n\n \n\n\n\n\n\nDr. Andrea Ballagi\, Olink Proteomics VP Sales and Marketing \n\n\n\nAndrea Ballagi has an MD from Semmelweis School of Medicine in Budapest\, a PhD in Cancer research from Ludwig Institute for Cancer Research in Uppsala and a MBA from Uppsala University. She started her industry career at IDEXX Laboratories located in Switzerland as a general manager and later moved back to Uppsala as a global technical service and product line manager in 2011. Andrea joined Olink in 2012 as director of commercial operations and has since been a major part of the company’s expansive growth phases. She currently serves as VP Sales and Marketing EMEA. \n\n\n\nAndrea has with her roots as an MD a real passion to change the way diagnostics is being conducted to in today’s clinical reality. By bringing in groundbreaking technological possibilities and unprecedented future treatment options made possible by the extensive Olink technological platform. \n\n\n\n\n\n\n\n\n\n\n\n\n\nDr. Simon Fredriksson\, Co-Founder Olink \n\n\n\nSimon Fredriksson has a PhD in Molecular Medicine from Uppsala University and conducted postdoctoral studies in biochemistry at Stanford University\, and most recently appointed Adjunct Professor at KTH. He is also the co-founder of Olink\, and both former CSO\, and CEO of the company in its formation and growth phases. His academic research resulted in multiple high impact publications and inventions that were commercialized into products. Most notably the Proximity-Ligation and -Extension assays for multiplex protein detection\, the main products of Olink Proteomics. \n\n\n\nIn 2015\, Simon co-founded and was the former CEO of Genagon Therapeutics\, a ground-breaking immuno-oncology company. Presently co-founder and CEO of Pixelgen Technologies\, and Partner in Colibri Ventures\, a premier life science business incubator\, that helps start-ups develop early ideas into successful companies faster and more efficient. Simon also has extensive board member experience from 9 years at Olink AB (partly exited to Nexttobe 2011)\, Biolamina AB (+6 years)\, Olink Proteomics AB (exited to Summa Equity 2019)\, and Cartana AB (exited to 10X Genomics 2020) and Genagon Therapeutics. \n\n\n\nAs an experienced life science entrepreneur\, researcher and inventor spanning from research tools to bio-therapeutics\, Simon has always been fascinated by technology innovation capable of pushing the frontiers of scientific discovery into new and unchartered territories. \n\n\n\n\n\n\n\n\n\n\n\n \n\n\n\nRegister to receive zoom link
URL:https://www.scilifelab.se/event/from-bmc-to-wall-street-old/
CATEGORIES:Event
ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2021/08/Clinical-Talks.png
ORGANIZER;CN="Clinical Talks":MAILTO:precisionmedicine@scilifelab.se
LOCATION:https://www.scilifelab.se/event/from-bmc-to-wall-street-old/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20210909T090000
DTEND;TZID=Europe/Stockholm:20210909T093000
DTSTAMP:20260404T213918
CREATED:20210903T140828Z
LAST-MODIFIED:20210906T140903Z
UID:10000438-1631178000-1631179800@www.scilifelab.se
SUMMARY:Clinical Talks: From BMC to Wall Street
DESCRIPTION:After our recent planning hiatus\, we now have the great pleasure to announce that “Clinical Talks” has been renewed for yet another exciting\, innovative\, and enlightening season. This season will focus on sustainable innovations within Life Sciences\, that have the potential to contribute to a better climate friendly future for our future generations. Also new this year is that the seminar is co-organized in a collaboration between SciLifeLab and KI Innovations. \n\n\n\nSeason 5\, will be held September until December 2021 with a total of seven scheduled Talks\, during Friday mornings 09-09:30 am via ZOOM (with some time-zone friendly adjustments for our international speakers). Each session consists of a talk given by our invited speaker followed by Q&A. The seminar is an open educational seminar series for our ever-expanding Life Science community. \n\n\n\nRead more about the clinical talk series here\n\n\n\n\n\n\n\n\n \n\n\n\n\n\nDr. Andrea Ballagi\, Olink Proteomics VP Sales and Marketing \n\n\n\nAndrea Ballagi has an MD from Semmelweis School of Medicine in Budapest\, a PhD in Cancer research from Ludwig Institute for Cancer Research in Uppsala and a MBA from Uppsala University. She started her industry career at IDEXX Laboratories located in Switzerland as a general manager and later moved back to Uppsala as a global technical service and product line manager in 2011. Andrea joined Olink in 2012 as director of commercial operations and has since been a major part of the company’s expansive growth phases. She currently serves as VP Sales and Marketing EMEA. \n\n\n\nAndrea has with her roots as an MD a real passion to change the way diagnostics is being conducted to in today’s clinical reality. By bringing in groundbreaking technological possibilities and unprecedented future treatment options made possible by the extensive Olink technological platform. \n\n\n\n\n\n\n\n\n\n\n\n\n\nDr. Simon Fredriksson\, Co-Founder Olink \n\n\n\nSimon Fredriksson has a PhD in Molecular Medicine from Uppsala University and conducted postdoctoral studies in biochemistry at Stanford University\, and most recently appointed Adjunct Professor at KTH. He is also the co-founder of Olink\, and both former CSO\, and CEO of the company in its formation and growth phases. His academic research resulted in multiple high impact publications and inventions that were commercialized into products. Most notably the Proximity-Ligation and -Extension assays for multiplex protein detection\, the main products of Olink Proteomics. \n\n\n\nIn 2015\, Simon co-founded and was the former CEO of Genagon Therapeutics\, a ground-breaking immuno-oncology company. Presently co-founder and CEO of Pixelgen Technologies\, and Partner in Colibri Ventures\, a premier life science business incubator\, that helps start-ups develop early ideas into successful companies faster and more efficient. Simon also has extensive board member experience from 9 years at Olink AB (partly exited to Nexttobe 2011)\, Biolamina AB (+6 years)\, Olink Proteomics AB (exited to Summa Equity 2019)\, and Cartana AB (exited to 10X Genomics 2020) and Genagon Therapeutics. \n\n\n\nAs an experienced life science entrepreneur\, researcher and inventor spanning from research tools to bio-therapeutics\, Simon has always been fascinated by technology innovation capable of pushing the frontiers of scientific discovery into new and unchartered territories. \n\n\n\n\n\n\n\n\n\n\n\n \n\n\n\nRegister to receive zoom link
URL:https://www.scilifelab.se/event/clinical-talks-from-bmc-to-wall-street/
CATEGORIES:Event
ATTACH;FMTTYPE=image/jpeg:https://www.scilifelab.se/wp-content/uploads/2021/09/ClinicalTalks_Season5_twitter_1024.jpg
ORGANIZER;CN="Clinical Talks":MAILTO:precisionmedicine@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20210910T130000
DTEND;TZID=Europe/Stockholm:20210910T135500
DTSTAMP:20260404T213918
CREATED:20210827T111000Z
LAST-MODIFIED:20210909T122434Z
UID:10000417-1631278800-1631282100@www.scilifelab.se
SUMMARY:BiG Talks - Metabolic Atlas: genome-scale metabolic models for easy browsing and analysis
DESCRIPTION:BiG Talks: Integrative Omics\n\n\n\nArranged by the SciLifeLab platforms for Bioinformatics\, Genomics and Diagnostics Development \n\n\n\nThe Bioinformatics and Genomics seminar series (“BiG Talks”) is an initiative arranged by the SciLifeLab platforms for Bioinformatics (NBIS)\, Genomics (NGI) and Clinical Genomics platform. The seminar series aims to give inspiration to the SciLifeLab community and to create new networking possibilities. Each event will be broadcasted over Zoom where you will be able to interact with the speakers\, and live broadcasted at the SciLifeLab YouTube channel.  \n\n\n\nIn this seminar series\, run in parallel with the ELIXIR-SE / NBIS workshop in Omics Integration and Systems Biology\, we will be broadcasting three seminars about research and tools for integration of omics data through systems biology approaches\, in humans and model organisms. Please use the following link to register and access the Zoom link:  \n\n\n\nRegistration\n\n\n\n\n\n\n\n\n\n8th of September\, 15:00 – 16:00 CET \n\n\n\nNetwork based analysis of 1002 GWAS study defines a pleiotropy map of human cell biologyDr. Pedro BeltraoGroup Leader\, EMBL-EBI\, United Kingdom \n\n\n\nMore info \n\n\n\n \n\n\n\n\n\n10th of September\, 13:00 – 13:55 CET \n\n\n\nThe Metabolic Atlas: genome-scale metabolic models for easy browsing and analysisMihail AntonProject Manager for Metabolic Atlas\, NBIS / Chalmers University\, Sweden \n\n\n\nMore info\, see below \n\n\n\n\n\n10th of September\, 14:00 – 15:00 CET \n\n\n\nNetwork-based integration and visualization of large-scale dataDr. Lars Juhl JensenGroup Leader\, Novo Nordisk Foundation Center for Protein Research\, Denmark \n\n\n\nMore info \n\n\n\n\n\n\n\n\n\n\nMetabolic Atlas: Genome-scale metabolic models for easy browsing and analysis\n\n\n\nMihail Anton\, Project Manager for Metabolic Atlas\, NBIS / Chalmers University of Technology\, Sweden \n\n\n\nAbstract \n\n\n\nAs science is advancing towards full reproducibility\, the ecosystem of tools and resources for genome-scale metabolic modelling is increasingly open-source. The talk will be centred on showcasing how Metabolic Atlas is aiding discovery of disease-related alterations of metabolism by contributing to this ecosystem. \n\n\n\nMetabolic Atlas integrates open-source GEMs of several model organisms\, and provides visualisations for these\, such as the Map Viewer via the manually curated 2D maps and the automatically generated 3D maps\, and the gene- and metabolite-centric Interaction Partners. In concert with other supporting features\, Metabolic Atlas is making open source genome-scale metabolic models easy to browse and analyse. \n\n\n\nThe talk will also promote a way to organise a model in a git repository\, the model test suite Memote\, and how this and other automations can be deployed on GitHub\, with the ultimate purpose of facilitating transparent community curation. \n\n\n\nBiography: In his role as project manager for Metabolic Atlas\, Mihail has been watching and contributing to the infrastructure supporting the development and community curation of genome scale metabolic models. Homepage: https://nbis.se/about/staff/mihail-anton/ \n\n\n\nHost: Rui Benfeitas\, NBIS Stockholm (rui.benfeitas@scilifelab.se) \n\n\n\nDate: September 10\, 13:00 – 13:55 CET online on Zoom \n\n\n\nBroadcast link (live event): SciLifeLab YouTube channel \n\n\n\n \n\n\n\nRegistration form for zoom link
URL:https://www.scilifelab.se/event/big-talks-2/
LOCATION:Online event via Zoom
CATEGORIES:Event
ORGANIZER;CN="BiG Talks":MAILTO:info@nbis.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20210910T130000
DTEND;TZID=Europe/Stockholm:20210910T150000
DTSTAMP:20260404T213918
CREATED:20210910T060532Z
LAST-MODIFIED:20210910T081453Z
UID:10000444-1631278800-1631286000@www.scilifelab.se
SUMMARY:BiG Talks - Integrative Omics
DESCRIPTION:Arranged by the SciLifeLab platforms for Bioinformatics\, Genomics and Diagnostics Development.\n\n\n\nHost: Rui Benfeitas\, NBIS Stockholm (rui.benfeitas@scilifelab.se) \n\n\n\nThe Bioinformatics and Genomics seminar series (“BiG Talks”) is an initiative arranged by the SciLifeLab platforms for Bioinformatics (NBIS)\, Genomics (NGI) and Clinical Genomics platform. The seminar series aims to give inspiration to the SciLifeLab community and to create new networking possibilities. Each event will be broadcasted over Zoom where you will be able to interact with the speakers\, and live broadcasted at the SciLifeLab YouTube channel.  \n\n\n\nIn this seminar series\, run in parallel with the ELIXIR-SE / NBIS workshop in Omics Integration and Systems Biology\, we will be broadcasting three seminars about research and tools for integration of omics data through systems biology approaches\, in humans and model organisms. Please use the following link to register and access the Zoom link. \n\n\n\nRegistration\n\n\n\n\n\n\n\n\n\n8th of September\, 15:00 – 16:00 CET \n\n\n\nNetwork based analysis of 1002 GWAS study defines a pleiotropy map of human cell biologyDr. Pedro BeltraoGroup Leader\, EMBL-EBI\, United Kingdom \n\n\n\nMore info \n\n\n\n \n\n\n\n\n\n10th of September\, 13:00 – 13:55 CET \n\n\n\nThe Metabolic Atlas: genome-scale metabolic models for easy browsing and analysisMihail AntonProject Manager for Metabolic Atlas\, NBIS / Chalmers University\, Sweden \n\n\n\nMore info\, see below \n\n\n\n\n\n10th of September\, 14:00 – 15:00 CET \n\n\n\nNetwork-based integration and visualization of large-scale dataDr. Lars Juhl JensenGroup Leader\, Novo Nordisk Foundation Center for Protein Research\, Denmark \n\n\n\nMore info\, see below \n\n\n\n\n\n\nMetabolic Atlas: Genome-scale metabolic models for easy browsing and analysis\n\n\n\nMihail Anton\, Project Manager for Metabolic Atlas\, NBIS / Chalmers University of Technology\, Sweden \n\n\n\nAbstract \n\n\n\nAs science is advancing towards full reproducibility\, the ecosystem of tools and resources for genome-scale metabolic modelling is increasingly open-source. The talk will be centred on showcasing how Metabolic Atlas is aiding discovery of disease-related alterations of metabolism by contributing to this ecosystem. \n\n\n\nMetabolic Atlas integrates open-source GEMs of several model organisms\, and provides visualisations for these\, such as the Map Viewer via the manually curated 2D maps and the automatically generated 3D maps\, and the gene- and metabolite-centric Interaction Partners. In concert with other supporting features\, Metabolic Atlas is making open source genome-scale metabolic models easy to browse and analyse. \n\n\n\nThe talk will also promote a way to organise a model in a git repository\, the model test suite Memote\, and how this and other automations can be deployed on GitHub\, with the ultimate purpose of facilitating transparent community curation. \n\n\n\nBiography: In his role as project manager for Metabolic Atlas\, Mihail has been watching and contributing to the infrastructure supporting the development and community curation of genome scale metabolic models. Homepage: https://nbis.se/about/staff/mihail-anton/ \n\n\n\nDate: September 10\, 13:00 – 14:00 CET online on Zoom \n\n\n\nregistration for both talks\n\n\n\n\n\n\n\nNetwork-based integration and visualization of large-scale data\n\n\n\nDr. Lars Juhl Jensen\, Group Leader\, Novo Nordisk Foundation Center for Protein Research\, Denmark \n\n\n\nAbstract \n\n\n\nNetworks are a powerful abstraction for modeling and visualizing the interplay between the many proteins within a cell. In this lecture\, I will first introduce the STRING database\, which uses the network abstraction to integrate a wide range of evidence types for physical protein interactions and functional association. This includes predicted interactions\, interactions from other public databases\, and automatic text mining of the biomedical literature. I will show a common use case of STRING\, namely network-based visualization of omics data via the Cytoscape stringApp. \n\n\n\nBiography \n\n\n\nDr. Lars Juhl Jensen started his research career in Søren Brunak’s group at the Technical University of Denmark (DTU)\, from where he in 2002 received the Ph.D. degree in bioinformatics for his work on non-homology-based protein function prediction. During this time\, he also developed methods for visualization of microbial genomes\, pattern recognition in promoter regions\, and microarray analysis. From 2003 to 2008\, he was at the European Molecular Biology Laboratory (EMBL) where he worked on literature mining\, integration of large-scale experimental datasets\, and analysis of biological interaction networks. Since 2009\, he has continued this line of research as a professor at the Novo Nordisk Foundation Center for Protein Research at the Panum Institute in Copenhagen and as a founder\, owner and scientific advisor of Intomics A/S. He is a co-author of more than 200 scientific publications that have in total received more than 40\,000 citations. He was awarded the Lundbeck Foundation Talent Prize in 2003\, his work on cell-cycle research was named “Break-through of the Year” in 2006 by the magazine Ingeniøren\, his work on text mining won the first prize in the “Elsevier Grand Challenge: Knowledge Enhancement in the Life Sciences” in 2009\, and he was awarded the Lundbeck Foundation Prize for Young Scientists in 2010. Homepage: https://jensenlab.org/ \n\n\n\nDate: September 10\, 14:00 – 15:00 CET online on Zoom \n\n\n\nregistration for both talks
URL:https://www.scilifelab.se/event/big-talks/
LOCATION:Online event via Zoom
CATEGORIES:Event
ORGANIZER;CN="BiG Talks":MAILTO:info@nbis.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20210910T140000
DTEND;TZID=Europe/Stockholm:20210910T150000
DTSTAMP:20260404T213918
CREATED:20210827T111618Z
LAST-MODIFIED:20210909T122507Z
UID:10000418-1631282400-1631286000@www.scilifelab.se
SUMMARY:BiG Talks - Network-based integration and visualization of large-scale data
DESCRIPTION:BiG Talks: Integrative Omics\n\n\n\nArranged by the SciLifeLab platforms for Bioinformatics\, Genomics and Diagnostics Development \n\n\n\nThe Bioinformatics and Genomics seminar series (“BiG Talks”) is an initiative arranged by the SciLifeLab platforms for Bioinformatics (NBIS)\, Genomics (NGI) and Clinical Genomics platform. The seminar series aims to give inspiration to the SciLifeLab community and to create new networking possibilities. Each event will be broadcasted over Zoom where you will be able to interact with the speakers\, and live broadcasted at the SciLifeLab YouTube channel.  \n\n\n\nIn this seminar series\, run in parallel with the ELIXIR-SE / NBIS workshop in Omics Integration and Systems Biology\, we will be broadcasting three seminars about research and tools for integration of omics data through systems biology approaches\, in humans and model organisms. Please use the following link to register and access the Zoom link:  \n\n\n\nRegistration\n\n\n\n\n\n\n\n\n\n8th of September\, 15:00 – 16:00 CET \n\n\n\nNetwork based analysis of 1002 GWAS study defines a pleiotropy map of human cell biologyDr. Pedro BeltraoGroup Leader\, EMBL-EBI\, United Kingdom \n\n\n\nMore info \n\n\n\n \n\n\n\n\n\n10th of September\, 13:00 – 13:55 CET \n\n\n\nMetabolic Atlas: genome-scale metabolic models for easy browsing and analysisMihail AntonProject Manager for Metabolic Atlas\, NBIS / Chalmers University\, Sweden \n\n\n\nMore info \n\n\n\n\n\n10th of September\, 14:00 – 15:00 CET \n\n\n\nNetwork-based integration and visualization of large-scale dataDr. Lars Juhl JensenGroup Leader\, Novo Nordisk Foundation Center for Protein Research\, Denmark \n\n\n\nMore info: See below \n\n\n\n\n\n\n\n\n\n\nNetwork-based integration and visualization of large-scale data\n\n\n\nDr. Lars Juhl Jensen\, Group Leader\, Novo Nordisk Foundation Center for Protein Research\, Denmark \n\n\n\nAbstract \n\n\n\nNetworks are a powerful abstraction for modeling and visualizing the interplay between the many proteins within a cell. In this lecture\, I will first introduce the STRING database\, which uses the network abstraction to integrate a wide range of evidence types for physical protein interactions and functional association. This includes predicted interactions\, interactions from other public databases\, and automatic text mining of the biomedical literature. I will show a common use case of STRING\, namely network-based visualization of omics data via the Cytoscape stringApp. \n\n\n\nBiography  \n\n\n\nDr. Lars Juhl Jensen started his research career in Søren Brunak’s group at the Technical University of Denmark (DTU)\, from where he in 2002 received the Ph.D. degree in bioinformatics for his work on non-homology-based protein function prediction. During this time\, he also developed methods for visualization of microbial genomes\, pattern recognition in promoter regions\, and microarray analysis. From 2003 to 2008\, he was at the European Molecular Biology Laboratory (EMBL) where he worked on literature mining\, integration of large-scale experimental datasets\, and analysis of biological interaction networks. Since 2009\, he has continued this line of research as a professor at the Novo Nordisk Foundation Center for Protein Research at the Panum Institute in Copenhagen and as a founder\, owner and scientific advisor of Intomics A/S. He is a co-author of more than 200 scientific publications that have in total received more than 40\,000 citations. He was awarded the Lundbeck Foundation Talent Prize in 2003\, his work on cell-cycle research was named “Break-through of the Year” in 2006 by the magazine Ingeniøren\, his work on text mining won the first prize in the “Elsevier Grand Challenge: Knowledge Enhancement in the Life Sciences” in 2009\, and he was awarded the Lundbeck Foundation Prize for Young Scientists in 2010. Homepage: https://jensenlab.org/ \n\n\n\nHost: Rui Benfeitas\, NBIS Stockholm (rui.benfeitas@scilifelab.se) \n\n\n\nDate: September 10\, 14:00 – 15:00 CET online on Zoom \n\n\n\nBroadcast link (live event): SciLifeLab YouTube channel  \n\n\n\n \n\n\n\n \n\n\n\nRegistration form for zoom link
URL:https://www.scilifelab.se/event/big-talks-3/
LOCATION:Online event via Zoom
CATEGORIES:Event
ORGANIZER;CN="BiG Talks":MAILTO:info@nbis.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20210913T161500
DTEND;TZID=Europe/Stockholm:20210913T173000
DTSTAMP:20260404T213918
CREATED:20210830T090518Z
LAST-MODIFIED:20210907T143831Z
UID:10000419-1631549700-1631554200@www.scilifelab.se
SUMMARY:The Svedberg seminar series: Dr. Aviv Regev
DESCRIPTION:Genentech\, USA \n\n\n\nHost: Erik Sonnhammer \, Stockholm University \n\n\n\nZOOM LINK  \n\n\n\n\n\n\n\n\n\nAviv Regev is a leader in deciphering molecular circuits that govern cells\, tissues and organs in health and their malfunction in disease. Her lab has pioneered foundational experimental and computational methods in single-cell genomics\, working toward greater understanding of the function of cells and tissues in health and disease\, including autoimmune disease\, inflammation and cancer \n\n\n\nCell atlases as roadmaps in health and disease\n\n\n\nCells are the basic unit of life\, and form a key intermediate between genotype and phenotype\, that is essential to explain how the gene variants that contribute to disease risk act. The recent advent of methods for high-throughput single-cell and spatial profiling has opened the way to create a human cells atlas: comprehensive reference maps of all human cells as a basis for both understanding human health and diagnosing\, monitoring\, and treating disease. From such maps we recovered rich aspects of biology\, including cell types and states\, differentiation and other temporal processes\, gene programs\, the physical location and interactions between cells\, the underlying regulatory circuits\, and even the possibility of predicting cell types and behaviors\, towards a “periodic table of our cells”. These\, in turn give us a new vocabulary for disease studies to determine the way in which cells do disease genes act\, which cells are disrupted in disease\, which programs change in them\, what mechanisms underlie their (dis)regulation\, how their cell-cell communications affected\, and what would be the impact of therapies. In this talk\, I will focus on how atlases help us to understand the relation between genotype to phenotype\, especially in the context of human genetics and disease\, from cells\, to programs\, to deciphering individual gene functions\, using single cell genomics as a conceptual and technical framework\, in complex disease\, cancer\, and COVID-19.Read more about Prof. Regev´s research HERE
URL:https://www.scilifelab.se/event/the-svedberg-seminar-series-prof-regev-aviv/
LOCATION:Online event via Zoom
CATEGORIES:Event
ORGANIZER;CN="The Svedberg Seminar Series":MAILTO:thesvedberg@scilifelab.uu.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20210914T130000
DTEND;TZID=Europe/Stockholm:20210914T150000
DTSTAMP:20260404T213918
CREATED:20210826T065213Z
LAST-MODIFIED:20210914T065424Z
UID:10000415-1631624400-1631631600@www.scilifelab.se
SUMMARY:The future of life science is data-driven - DDLS update and strategy
DESCRIPTION:Welcome\n\n\n\nto an online meeting where the Data-driven Life Science (DDLS) strategy will be introduced and discussed. The SciLifeLab and Wallenberg National Program on Data-Driven Life Science (DDLS) program’s ongoing activities and progress of the program will also be presented.   \n\n\n\nAim\n\n\n\nThe purpose of the meeting is to introduce and discuss the DDLS strategy; to present ongoing activities and program achievements; and to engage community and stakeholders. The aim of the panel discussion and input from participants is to facilitate further development of the strategy.   \n\n\n\nTarget group\n\n\n\nWe welcome partner organizations\, collaborators nationally\, the Swedish life science community\, industry\, healthcare as well as other stakeholders in the society at large.   \n\n\n\nProgram\n\n\n\nWelcome wordsOlli Kallioniemi\, Director of SciLifeLab and DDLS program and Siv Andersson\, KAWThe initiative and its importanceHans Adolfsson\, vice-chancellor Umeå University\, chairman of HuvudmannarådetEuropean perspective\, experience from EMBLJan Korbel\, Senior Scientist Genome Biology & Head of Data Science\, EMBL HeidelbergDDLS update and presentation of DDLS strategyOlli Kallioniemi DDLS research areasEvolution and Biodiversity: Fredrik RonquistPrecision Medicine and Diagnostics: Janne LehtiöCell and Molecular Biology: Emma LundbergEpidemiology and Infection Biology: Oliver BillkerData processJohan Rung\, Head of SciLifeLab Data centrePanel discussion​​Moderator: Anna Frejd\, Communications manager\, SciLifeLabClosing wordsOlli Kallioniemi and Siv Andersson\n\n\n\n\n\n\n\nRead the strategy\n\n\n\nShare your thoughts on the strategy
URL:https://www.scilifelab.se/event/the-future-of-life-science-is-data-driven-ddls-update-and-strategy/
CATEGORIES:Event
ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2020/10/Map-DDLS-illustration_dove.png
ORGANIZER;CN="Data-Driven Life Science @ SciLifeLab":MAILTO:ddls@scilifelab.se
LOCATION:https://www.scilifelab.se/event/the-future-of-life-science-is-data-driven-ddls-update-and-strategy/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20210915T151500
DTEND;TZID=Europe/Stockholm:20210915T164500
DTSTAMP:20260404T213918
CREATED:20210907T145743Z
LAST-MODIFIED:20210909T064420Z
UID:10000440-1631718900-1631724300@www.scilifelab.se
SUMMARY:SciLifeLab COVID-19 seminars: Cornelis Melief and Sara Mangsbo
DESCRIPTION:The second seminar in this series starts with Cornelis Melief\, Emeritus professor of immunology at Leiden University and Chief Scientific Officer (CSO) of ISA Pharmaceuticals\, who will talk about T cell-based vaccination against SARS-CoV-2.  \n\n\n\nSara Mangsbo\, Senior lecturer in Antibody drugs and Associate professor in Experimental clinical immunology\, Uppsala University\, then continues the seminar by talking about T cell responses to SARS-CoV-2\, what have we learned so far? \n\n\n\nHost:  Alice Sollazzo\, Project coordinator\, SciLifeLab Operations Office \n\n\n\n\n\n\n\nRegistration is mandatory to get the Zoom link for the event \n\n\n\n\n\n\n\n\nREGISTRATION\n\n\n\n\n\n\n\n\nProgram\n\n\n\n15:15T cell-based vaccination against SARS-CoV-2 Cornelis Melief\, Emeritus professor of immunology at Leiden University16:00T cell responses as SARS-CoV-2\, what have we learned so far? Sara Mangsbo\, Senior lecturer in Antibody drugs\, Uppsala University\n\n\n\nBios and abstracts\n\n\n\nDownload:Download
URL:https://www.scilifelab.se/event/scilifelab-covid-19-seminars-cornelis-melief-and-sara-mangsbo/
LOCATION:Online event via Zoom
CATEGORIES:Event
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20210920T151500
DTEND;TZID=Europe/Stockholm:20210920T163000
DTSTAMP:20260404T213918
CREATED:20210816T082333Z
LAST-MODIFIED:20210916T154406Z
UID:10000407-1632150900-1632155400@www.scilifelab.se
SUMMARY:The Svedberg seminar series: Assoc. Prof. Daniel Globisch
DESCRIPTION:SciLifeLab Fellow at Uppsala University / Dept. Chem – BMC \n\n\n\nLINK TO SEMINAR \n\n\n\n\n\n\n\n\n\nAssociate Professor Daniel Globisch started his independent research group as a Science For Life Laboratory Fellow at Uppsala University. In December 2020\, Daniel Globisch received tenure and moved with his laboratory to the Department of Chemistry – BMC. He received his PhD in Organic Chemistry and Chemical Biology in 2011 at the Ludwig-Maximilians-University in Munich and joined The Scripps Research Institute\, La Jolla\, CA for his postdoctoral research in Chemical Biology and Metabolomics from 2011 to 2015. At Uppsala University\, his laboratory develops new Chemical Biology methodologies to extend the scope of metabolomics research to discover new biomarkers for pancreatic and colorectal cancer. The interdisciplinary nature of the research projects is focussed on elucidation of the metabolic interaction between the gut microbiota and their human host. \n\n\n\nExploring Gut Microbiota Metabolism – Unique Chemical Biology Tools for Metabolomics Analysis\n\n\n\nOne of the most exciting scientific developments in the past decade has been the understanding that the microbiome profoundly impacts human physiology. The complex consortium of trillions of microbes possesses a wide range of metabolic activity. This metabolic interspecies communication represents a tremendous opportunity for the discovery of unknown bioactive molecules as only limited information on this co-metabolism has been elucidated on a molecular level. Metabolomics holds a great potential for the discovery of unknown biomarkers and bioactive metabolites. Advanced Chemical Biology tools are limited compared to other ‘omics research fields. Especially\, the detailed analysis of microbial metabolism remains a major challenge and requires advanced techniques. We have developed unique Chemical Biology methodologies for enhanced analysis using liquid chromatography-coupled with tandem mass spectrometry. These tools overcome limitations in mass spectrometry-based metabolomics analysis. We apply these methods for the discovery of unknown metabolites in human samples collected from pancreatic cancer patients to evaluate their potential as biomarkers.
URL:https://www.scilifelab.se/event/the-svedberg-seminar-series-assoc-prof-daniel-globisch/
LOCATION:Online event via Zoom
CATEGORIES:Event
ORGANIZER;CN="The Svedberg Seminar Series":MAILTO:thesvedberg@scilifelab.uu.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20210922T110000
DTEND;TZID=Europe/Stockholm:20210922T174500
DTSTAMP:20260404T213918
CREATED:20210830T133010Z
LAST-MODIFIED:20210917T101612Z
UID:10000420-1632308400-1632332700@www.scilifelab.se
SUMMARY:Pushing the Frontiers 2021
DESCRIPTION:The Scientific Director for SciLifeLab-UU and the SciLifeLab-UU Committee welcomes you to Pushing the Frontiers 2021.  \n\n\n\n \n\n\n\nThis is a one-day scientific event where two SciLifeLab fellow alumni at Uppsala University and many of the 21 postdocs financed by the SciLifeLab-UU postdoc programs of 2017-2018 will share their research progress with the local SciLifeLab community.  \n\n\n\nPresentation format: Postdocs: 10 min + 5 min discussion. Fellows: 25 min+5 min discussion. \n\n\n\nOrganizers: SciLifeLab committee UU\, The SciLifeLab-UU working group: Staffan Svärd\, Jenny Alfredsson\, Titti Ekegren\, Aristidis Moustakas\, Mikael Widersten. \n\n\n\nIf you have any questions\, please contact events@SciLifeLab.se \n\n\n\n\n\n\n\nHybrid event\n\n\n\nThe event is a hybrid event. Lunch and coffee will be served in Navet. \n\n\n\nWe have 40 seats (Corona distance) in the Triple room of Navet at BMC\, Uppsala (principle of first come\, first served). To enter Navet\, please bring your QR code ticket. We care about your health. To join in person\, we want you to be fully vaccinated. If you register to be on-site but change your mind\, please adjust your registration with the link in the confirmation email. \n\n\n\nA link to the Zoom meeting and a QR code ticket to enter Navet will be provided in the confirmation email. \n\n\n\n \n\n\n\n\n\n\n\n\n\n\n\nProgram\n\n\n\n09:00WelcomeStaffan Svärd & SciLifeLab-UU CommitteeChair: Mikael Widersten09:00Single nuclei RNA-sequencing from metabolic tissuesMarco Cavalli 09:15Exploring deep human roots in south-central African ancient and modern genetic dataNina Hollfelder 09:30A time-resolved imaging-based CRISPRi screening methodDaniel Camsund09:45A novel mitochondrion-related organelle revealed through comparative genomics of the uncultured protist parasite Paramikrocytos canceri (Rhizaria\, Ascetosporea)Ioana Onut Brannström10:00Coffee break10:30Conservation of G-quadruplexes and other GC-rich regions of avian genomesJulie Blommaert 10:45Monoallelic and bi-allelic variants in NCDN cause neurodevelopmental delay\, intellectual disability\, and epilepsyAmbrin Fatima11:00Microfluidic solution for electroporation of dye-labelled biological macromolecules into E. coliZahra Atena KhajiFellows session:11:15Chemistry – Chemical Biology and biomarkersDaniel Globisch11:45Lunch breakChair: Aristidis Moustakas12:30Protein machines at single molecule levelSebastian Deindl13:00The DNA methylome of adult and pediatric relapsed acute myeloid leukemiaMahsa Shahidi Dadras13:15Genomics-driven exploration of Asgard archaeal symbioses to gain insight in the origin of eukaryotesCourtney Stairs 13:30Fungal-bacterial metabolic interactions in the deep biosphereMaliheh Mehrshad13:45Development and clinical implementation of advanced technologies for detection of exosomes as biomarkers with relevance for prostate cancerLiza Löf14:00Characterizing cell origin and co-operative mutations of MYC-driven brain cancerMiao Zhao14:15Using organotypic tissue culture to decipher the host cell tropism of invasive gut bacteriaJorik van Rijn14:30CRISPR/Cas9 “multi-hit” mutations to decipher the role of heparan sulfate N-sulfation in embryonic developmentLaura Waldmann14:45Coffee breakChair: Staffan Svärd15:00Open discussionThe future of SciLifeLab (including: the postdoctoral program at UU): aims\, expectations\, achievements\, future perspectives. We want to hear your thought on the future of SciLifeLab at UU.15:30Concluding remarksStaffan Svärd & SciLifeLab-UU Committee15:45End of day
URL:https://www.scilifelab.se/event/pushing-the-frontiers-2021/
LOCATION:Navet\, SciLifeLab Uppsala\, SciLifeLab Uppsala\, BMC C11\, Husargatan 3\, Uppsala\, 75237\, Sweden
CATEGORIES:Event
ATTACH;FMTTYPE=image/jpeg:https://www.scilifelab.se/wp-content/uploads/2021/08/MG_8501-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20210923T080000
DTEND;TZID=Europe/Stockholm:20210924T170000
DTSTAMP:20260404T213918
CREATED:20210628T112516Z
LAST-MODIFIED:20210628T112631Z
UID:10000402-1632384000-1632502800@www.scilifelab.se
SUMMARY:Annual Symposium on ATP1A3 in Disease
DESCRIPTION:Sweden is a child-friendly country with long traditions in pediatric care and research. We will introduce some new aspects in AHC and ATP1A3 related disease that should open up for new research projects and new therapeutic strategies. \n\n\n\nPreliminary\, our main themes will be: \n\n\n\nThe origin of gait disturbances;The origin and recording of pain;The lipid environment of the ATP1A3 molecule\n\n\n\nThe 9th Annual Symposium was originally planned to take place in October 2020\, but due to the current pandemic we unfortunately had to postpone the meeting. Detailed planning of the 2021 Symposium in Stockholm is ongoing and updates will continually be announced on this website. \n\n\n\nIn our time of Covid-19 pandemic\, we can assure possibility for social distancing in our conference venue\, Aula Medica of Karolinska Institutet Campus Solna. The main hall is approximated for up to 1\,000 persons\, and will give plenty of space for our symposium which is planned for 100-120 persons. \n\n\n\nPlease stay tuned and stay safe! \n\n\n\nOn behalf of the Organizing committee \n\n\n\nAnita Aperia      Eli Gunnarson     Hjalmar Brismar
URL:https://www.scilifelab.se/event/annual-symposium-on-atp1a3-in-disease/
LOCATION:Aula Medica\, Nobels väg 6\, Solna
CATEGORIES:Event
ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2021/06/atp21-logo-sept-1200-2.png
ORGANIZER;CN="Akademikonferens":MAILTO:ATP1A3-2021@akademikonferens.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20210924T080000
DTEND;TZID=Europe/Stockholm:20210924T170000
DTSTAMP:20260404T213918
CREATED:20210908T125241Z
LAST-MODIFIED:20220330T154121Z
UID:10000441-1632470400-1632502800@www.scilifelab.se
SUMMARY:Researcher’s Night at SciLifeLab
DESCRIPTION:The European Researchers’ Night is a Europe-wide public event\, which displays the diversity of science and its impact on citizens’ daily lives in fun\, inspiring ways. This year\, the event will take place in 29 countries on Friday 24 September 2021. \n\n\n\nThe European Researchers’ Night aims to \n\n\n\nbring research and researchers closer to the publicpromote excellent research projects across Europe and beyondincrease the interest of young people in science and research careersshowcase the impact of researchers’ work on people’s daily lives\n\n\n\nIn Sweden\, activities will be organised across the country and online under the name ForskarFredag (Researchers’ Friday) coordinated by the Swedish nonprofit organisation Vetenskap & Allmänhet \n\n\n\nOpen to schools and individuals from all of over Sweden. Please register at Vetenskapens hus’ website to receive the zoom-link. \n\n\n\nRead more and register\n\n\n\nSciLifeLab will participate in Researcher’s night as part of Vetenskapens Hus program\, with a set of lectures orchestrated by the Public Engagement Committee. We invite participants from schools all over Sweden to tune in to interesting lectures by our researchers. The lectures are given in English\, are 15 minutes long and are followed by the opportunity for discussion with the researcher for another 15 minutes. They cover varying topics such as how spaceflight affect astronauts’ bodies and how different microscopical techniques can be used to study the cellular world. \n\n\n\n \n\n\n\n09:00How does spaceflight affect astronauts’ bodies?Stefania Giacomello\, KTH10:00Is weight-loss surgery properly restoring insulin response?Carsten Daub\, Karolinska Institutet/SciLifeLab11:00Cellular world observed with microscopy – in two partsErdinc Sezgin\, Karolinska Institutet/SciLifeLab\, Marta Carroni\, Stockholm University/SciLifeLab14:00Hidden treasure: an immunological master switch deep in our gutsLuisa Hugerth\, Karolinska Institutet/SciLifeLab15:00Sex differences in the immune systemCamila Rosat Consiglio\, Karolinska Institutet/SciLifeLab
URL:https://www.scilifelab.se/event/researchers-night-at-scilifelab/
LOCATION:Online event via Zoom
CATEGORIES:Event
ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2021/09/Forskarfredag.png
ORGANIZER;CN="SciLifeLab Event":MAILTO:events@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20210924T080000
DTEND;TZID=Europe/Stockholm:20210924T170000
DTSTAMP:20260404T213918
CREATED:20240909T095320Z
LAST-MODIFIED:20240925T074739Z
UID:10001349-1632470400-1632502800@www.scilifelab.se
SUMMARY:Researcher’s Night at SciLifeLab
DESCRIPTION:The European Researchers’ Night is a Europe-wide public event\, which displays the diversity of science and its impact on citizens’ daily lives in fun\, inspiring ways.  \n\n\n\nThe European Researchers’ Night aims to \n\n\n\n\nbring research and researchers closer to the public\n\n\n\npromote excellent research projects across Europe and beyond\n\n\n\nincrease the interest of young people in science and research careers\n\n\n\nshowcase the impact of researchers’ work on people’s daily lives\n\n\n\n\nIn Sweden\, activities will be organised across the country and online under the name ForskarFredag (Researchers’ Friday) coordinated by the Swedish nonprofit organisation Vetenskap & Allmänhet \n\n\n\nRead more and register\n\n\n\n\n\nForskarfredag SciLifeLab 2024Download
URL:https://www.scilifelab.se/event/researchers-night-at-scilifelab-2/
LOCATION:Air&Fire\, SciLifeLab Stockholm\, Tomtebodavägen 23A\, Solna\, Sweden
CATEGORIES:Event
ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2021/09/Forskarfredag.png
ORGANIZER;CN="SciLifeLab Event":MAILTO:events@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20210928T151500
DTEND;TZID=Europe/Stockholm:20210928T163000
DTSTAMP:20260404T213918
CREATED:20210923T094943Z
LAST-MODIFIED:20210923T122525Z
UID:10000453-1632842100-1632846600@www.scilifelab.se
SUMMARY:The Svedberg seminar series: Prof. Ana Pombo
DESCRIPTION:MDC Berlin Institute for Medical Systems Biology (BIMSB) \, Humboldt University\, Germany \n\n\n\nLINK TO SEMINAR \n\n\n\n\n\n\n\n\n\nAna Pombo investigates mechanisms that regulate 3D genome folding and gene expression during mammalian  development and in disease. After her doctorate work at the University of Oxford (UK)\, Ana was a recipient of a Royal Society Dorothy Hodgkin Fellowship. She started her independent group in 2000\, at the MRC London Institute for Medical Sciences\, Imperial College London\, before moving to the Max Delbrueck Center for Molecular Medicine in Berlin\, in Germany. Ana received the Robert Feulgen Prize in 2007\, and was elected EMBO member in 2018. She is a Professor at the Humboldt University of Berlin and the Deputy Scientific Directed of the Berlin Institute for Medical Systems Biology at MDC. \n\n\n\nFunctional specialization of 3D genome structures in brain cell types\n\n\n\nDuring lineage commitment\, cells sustain cascades of gene activation and repression to generate specific cell types that execute specialized functions. To investigate the variability of the 3D conformation of the genome in different cell types and their relation with cell-type specific patterns of gene expression\, we applied Genome Architecture Mapping is specific brain cell types from the adult murine brain\, without disturbing their native tissue environment: dopaminergic neurons (DNs) from the midbrain\, pyramidal glutamatergic neurons (PGNs) from the hippocampus\, and oligodendrocyte lineage cells (OLGs) from the cortex. We find extensive reorganization of genome topology\, which the reorganization of topological domains\, chromatin compartments and specific long-range hubs of contacts between neuron-specific genes. We also discover events of extensive chromatin decondensation\, or ‘melting’\, at long neuronal genes when they are highly transcribed\, many of them associated with neurodevelopmental disorders or neurodegeneration. Our work shows that the 3D organization of the genome is highly specific of cell type and strongly related with gene expression programs.Read more about Ana Pombo`s research: https://www.mdc-berlin.de/pomboHost:  Eva Brinkman\, KI
URL:https://www.scilifelab.se/event/the-svedberg-seminar-series-prof-ana-pombo/
LOCATION:Online event via Zoom
CATEGORIES:Event
ORGANIZER;CN="The Svedberg Seminar Series":MAILTO:thesvedberg@scilifelab.uu.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20210930T130000
DTEND;TZID=Europe/Stockholm:20210930T150000
DTSTAMP:20260404T213918
CREATED:20210924T134253Z
LAST-MODIFIED:20210924T134331Z
UID:10000454-1633006800-1633014000@www.scilifelab.se
SUMMARY:SuperResolutionMiniSymposia
DESCRIPTION:13:00-13:50 Accessing the nanoscale with MINFLUXFrancisco Balzarotti (IMP Vienna)Topic: new super resolution light microscopy method to image proteins and DNA with 1 nm spatial resolution.Of interest for the imaging and biophysics community \n\n\n\n14-14:50Imaging more labels using ’smart’ probes and PSF engineeringPeter Dedecker (Leuven University)Topic: multiplexing light microscopy with smart probes and optical development. \n\n\n\n \n\n\n\nHybrid Meeting – Join in Air&Fire or Join Zoom Meeting: \n\n\n\nhttps://kth-se.zoom.us/j/61036958775?pwd=VVpXVmJDQUFzVCttR2FaNFY2Nm9zQT09Meeting ID: 610 3695 8775Password: 028016
URL:https://www.scilifelab.se/event/superresolutionminisymposia/
LOCATION:Air&Fire\, SciLifeLab Stockholm\, Tomtebodavägen 23A\, Solna\, Sweden
CATEGORIES:Event
ORGANIZER;CN="Ilaria Testa":MAILTO:ilaria.testa@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20210930T170000
DTEND;TZID=Europe/Stockholm:20210930T173000
DTSTAMP:20260404T213918
CREATED:20210908T154652Z
LAST-MODIFIED:20210910T122137Z
UID:10000442-1633021200-1633023000@www.scilifelab.se
SUMMARY:Clinical Talks: Detect cancer early\, while it still can be cured
DESCRIPTION:On September 30\, Dr. Hyunsung John Kim\, will talk about the amazing potential RNA liquid biopsies can offer modern healthcare\, by detecting cancer early\, while it still can be cured. Resulting in a total transformation of cancer care\, ultimately allowing for a more efficient\, cost-effective\, and sustainable healthcare. While working as a senior Bioinformatician at Illumina\, John was part of the founding team who branched out GRAIL\, with its very promising Galleri multi-cancer early detection test soon to hit our Clinical reality.  \n\n\n\nRegister to receive zoom link\n\n\n\n\n\n\n\nJohn develops cloud computing tools that use machine learning and AI to generate biological insights from large clinically relevant datasets. He has worked in Next Generation Sequencing (NGS) and bioinformatics for over ten years in academic and industrial settings. \n\n\n\nHe started his career at the University of California at Santa Cruz where he received the Chancellor’s fellowship for designing new sequencing assays and algorithms for diagnostics and immunology. After receiving his PhD in Bioinformatics and Biomolecular Engineering\, John joined the Advanced Research group at Illumina. There he played a critical role in launching Illumina’s single cell product by developing the accompanying cloud-based bioinformatics software and was given the CEO award for his contributions. \n\n\n\nJohn departed from Illumina to make a significant impact on the fight against cancer by joining GRAIL Inc. as one of its founding members. At GRAIL\, he led a team of data scientists\, software engineers and statisticians as a bioinformatics technical lead. His team worked to gain a better understanding cell free nucleic acids and develop diagnostic products that detect cancer earlier than the current standard of care. John holds multiple patents and was an author on the first patent awarded to GRAIL. In addition\, he has co-authored peer-reviewed publications on his work related to the early cancer detection from cell free nucleic acids. \n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\nClinical Talks Series\n\n\n\nAfter our recent planning hiatus\, we now have the great pleasure to announce that “Clinical Talks” has been renewed for yet another exciting\, innovative\, and enlightening season. This season will focus on sustainable innovations within Life Sciences\, that have the potential to contribute to a better climate friendly future for our future generations. Also new this year is that the seminar is co-organized in a collaboration between SciLifeLab and KI Innovations. \n\n\n\nRead more about the clinical talk series here\n\n\n\nSeason 5\, will be held September until December 2021 with a total of seven scheduled Talks\, during Friday mornings 09-09:30 am via ZOOM (with some time-zone friendly adjustments for our international speakers). Each session consists of a talk given by our invited speaker followed by Q&A. The seminar is an open educational seminar series for our ever-expanding Life Science community.
URL:https://www.scilifelab.se/event/clinical-talks-detect-cancer-early-while-it-still-can-be-cured/
LOCATION:Online event via Zoom
CATEGORIES:Event
ATTACH;FMTTYPE=image/jpeg:https://www.scilifelab.se/wp-content/uploads/2021/09/ClinicalTalks_Season5_twitter_1024.jpg
ORGANIZER;CN="Clinical Talks":MAILTO:precisionmedicine@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20211001T090000
DTEND;TZID=Europe/Stockholm:20211001T110000
DTSTAMP:20260404T213918
CREATED:20210902T060431Z
LAST-MODIFIED:20210902T060444Z
UID:10000424-1633078800-1633086000@www.scilifelab.se
SUMMARY:BioImage Informatics Call4Help
DESCRIPTION:Every 1st week of the month (mainly on Tuesdays\, but there might be exceptions) the BioImage Informatics Facility together with microscopy expert Sylvie Le Guyader (LCI\, Karolinska Institutet) organizes a Call4Help session. The aim is to offer combined expertise towards microscopy and bioimage analysis. All researchers from Swedish institutes can participate. \n\n\n\nThe ideal timepoint to join the Call4Help session is when a researcher has performed pilot experiments and has tried out first analysis approaches – but before having recorded hundreds of images. Combining BIIF’s expertise in BioImage Analysis with microscopy expertise we can discuss ways to record the images that allow analysis afterwards. We will discuss different analysis approaches using mainly open-source software (Fiji\, CellProfiler\, QuPath\, Ilastik\, KNIME)\, but also commercial systems\, if needed (Imaris). \n\n\n\nThe Call4Help session format has been introduced to the BioImage Analysis community by NEUBIAS and ScopeM. \n\n\n\nHow to participate? \n\n\n\nStep1: \n\n\n\nPrepare a short presentation (5-7 min)  – use the following template for your presentation: \n\n\n\nhttp://bit.ly/BIIF_C4H_slideTemplate \n\n\n\nSlide template by NEUBIAS/ScopeM \n\n\n\nStep2: \n\n\n\na) Upload your presentation \n\n\n\nUpload your presentation to a drive of your choice. You can also use our Call4Help google drive. Note that files shared on our Call4Help drive will be available to everyone until the session is over. \n\n\n\nhttp://bit.ly/BIIF_C4H_Drive \n\n\n\nb) Upload example images for testing. \n\n\n\nUpload example images for testing either to the drive of your choice or our Call4Help google drive above. \n\n\n\nhttp://bit.ly/BIIF_C4H_Drive \n\n\n\nc) Register by filling out the registration form: \n\n\n\nhttp://bit.ly/BIIF_C4H_Registration \n\n\n\nStep 3: \n\n\n\nJoin the zoom-session. \n\n\n\nIf your problem is selected for presentation\, you will get a time-slot of 30 – 60 minutes within the session. \n\n\n\nWhat are the Deadlines \n\n\n\nSubmission of a problem and upload of example data: Deadline for application: Tuesday\, September 28\, 2021. \n\n\n\nNotification about participation: The day before the session. \n\n\n\nNext Call4Help session \n\n\n\nFriday\, October 1\, 2021\, 9.00-12.00. Deadline for application: Tuesday\, September 28\, 2021.
URL:https://www.scilifelab.se/event/bioimage-informatics-call4help-4/
CATEGORIES:Event
ORGANIZER;CN="Bioimage Informatics Unit":MAILTO:biif@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20211004T151500
DTEND;TZID=Europe/Stockholm:20211004T161500
DTSTAMP:20260404T213918
CREATED:20210916T094629Z
LAST-MODIFIED:20210923T122426Z
UID:10000447-1633360500-1633364100@www.scilifelab.se
SUMMARY:The Svedberg seminar series: Ass. Prof. Daniel Espes
DESCRIPTION:SciLifeLab Fellow at Uppsala University \n\n\n\nLINK TO SEMINAR \n\n\n\n\n\n\n\n\n\nDaniel Espes received his completed his PhD at the Department of Medical Cell Biology\, Uppsala University\, in 2016 and became an Associate Professor (Docent) in Medical Cell Biology in 2019. In parallel with his research career he has worked actively as a clinical physician and became a specialist in internal medicine in 2019. In 2021 Espes joined as a SciLife Fellow and his translational group is focused on the development of clinically applicable techniques for assessing beta-cell mass alterations within the human pancreas during the development of diabetes. \n\n\n\nImagine Imaging Beta-Cell Mass\n\n\n\nType 1 diabetes is one of the most common chronic disease among children and adolescents. Due to the long-term complications associated with the disease the life-expectancy for those living with the disease is reduced by more than 10 years. Type 1 diabetes develops due to progressive loss of the insulin producing beta-cells following an immune attack. However\, the underlying trigger for the immune system is still unknown. At onset of hyperglycemia 60-70% of the beta-cell mass have already been lost\, based on data from autopsy studies. Currently there are no validated techniques for evaluating beta-cell mass in vivo in humans and hence our understanding of how beta-cell mass is altered in health and disease is limited to what we have learned from autopsy material. Our work is focused on establishing novel techniques for the quantification of beta-cell mass in order to increase our understanding of how diabetes develops as well as how beta-cell mass adapts in response to other conditions. In addition\, we are trying to better understand the immunological and metabolic interactions within the pancreas by combining imaging techniques with functional assessments. \n\n\n\nHost: Ass. Prof. Gustaf Christoffersson
URL:https://www.scilifelab.se/event/the-svedberg-seminar-series-assoc-prof-daniel-espes/
LOCATION:Online event via Zoom
CATEGORIES:Event
ORGANIZER;CN="The Svedberg Seminar Series":MAILTO:thesvedberg@scilifelab.uu.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20211005T090000
DTEND;TZID=Europe/Stockholm:20211008T170000
DTSTAMP:20260404T213918
CREATED:20210503T141305Z
LAST-MODIFIED:20210503T141929Z
UID:10000376-1633424400-1633712400@www.scilifelab.se
SUMMARY:15th Nordic Photosynthesis Congress
DESCRIPTION:You are cordially invited to attend the NPC15 at the Conference Center Wallenberg\, Gothenburg in Sweden.The congress will highlight the latest discoveries in photosynthesis and related fields along with a view to the future of how to sustain the expanding life on our planet. Alongside presentations of biological results\, there will be methodological advances\, and students and postdocs are encouraged to apply for talks. \n\n\n\nNPC15 is the only physical photosynthesis conference in Europe this year. Therefore\, we specifically welcome all international photosynthesis researchers to attend our conference. \n\n\n\nTopics\n\n\n\nMetabolic engineering of carbon fixationStructure and function of photosynthetic complexesNovel methods to study photosynthesisRegulation of photosynthesisArtificial photosynthesis and hybrid systems\n\n\n\nConfirmed invited speakers\n\n\n\nKeynote lectureEva-Mari Aro\,University of Turku\, Finland \n\n\n\nMetabolic engineering and carbon fixationCecilia Blikstad\, Uppsala University\, SwedenPeter Lindblad\, Uppsala University\, Sweden \n\n\n\nStructure and function of photosynthetic complexesMatthew Johnson\,University of Sheffield\, UKNathan Nelson\,University of Tel Aviv\, Israel \n\n\n\nNovel methods to study photosynthesisBen Engel\, Helmholtz Zentrum Munich\, GermanyAlizée Malnoë\, Umeå University\, Sweden \n\n\n\nRegulations of photosynthesisUte Armbruster\, Max Planck Institute Golm\, GermanyRoberta Croce\, University of Amsterdam\, NetherlandsBill Rutherford\, Imperial College London\, UK \n\n\n\nArtificial photosynthesis and hybrid systemsKirstin Gutekunst\,University of Kiel\, GermanyMarc Robert\, Université de Paris\, France
URL:https://www.scilifelab.se/event/15th-nordic-photosynthesis-congress/
LOCATION:Conference Centre Wallenberg\, Medicinaregatan 20A\, Gothenburg\, 413 90\, Sweden
CATEGORIES:Event
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20211007T110000
DTEND;TZID=Europe/Stockholm:20211007T120000
DTSTAMP:20260404T213918
CREATED:20210930T131922Z
LAST-MODIFIED:20210930T132333Z
UID:10000458-1633604400-1633608000@www.scilifelab.se
SUMMARY:The current state of modeling protein motions : from physics to AI
DESCRIPTION:Location \n\n\n\nKinnekulle\, alfa 5\, Scilifelab (limited seatings) \n\n\n\n \n\n\n\n\n\n \n\n\n\nOnline \n\n\n\njoin zoom meeting\n\n\n\n \n\n\n\n \n\n\n\n\n\nInvited speaker: \n\n\n\nSergei Grudinin\, LJK CNRS Grenoble\, France\n\n\n\nArtificial intelligence\, and more specifically deep learning\, has recently emerged as a powerful approach to exploit the massive amounts of protein sequence and structure data available nowadays toward guiding biological intervention to improve human health. A couple of months ago\, the alphaFold2 architecture from DeepMind revolutionised the field of protein structure prediction by reaching unprecedented levels of near-experimental accuracy. This achievement has been made possible mostly thanks to the latest improvements in geometric learning and natural language processing (NLP) techniques.  \n\n\n\nWhile the problem of determining how a protein folds in three dimensions (3D) is essentially solved\,  accessing protein motions is becoming more central than ever before [1]. At the European level\, the ELIXIR community is investing efforts right  now to create a comprehensive resource for structural diversity and flexibility in the Protein Data Bank (PDB)\, which contains all experimentally-determined protein 3D structures. Indeed\, proteins are flexible biological objects\, constantly moving and changing their shape to interact with their environment and cellular partners. This inherent flexibility is highly relevant for protein functioning. Experimentally\, it is very difficult to observe proteins directly in action\, and we have mostly access to isolated clusters of “snapshots” (conformations) representative of a few functional states.  \n\n\n\nI will present relatively simple physics-based models developed in our team\, where the protein is represented by an elastic network. They have proven very useful to nonlinearly extrapolate functional motions\, starting from a single structure and predict structural protein transitions [2-4]. I will also show an extension of these developments to construct a multi-level representation of protein flexibility. Then\, I will outline the current state of AI methods to model protein structural heterogeneity and connect it with the physics-based models. \n\n\n\nReferences \n\n\n\n[1] Laine\, Elodie\, et al. “Protein sequence-to-structure learning: Is this the end (-to-end revolution)?.” Proteins in Press (2021).[2] Laine\, Elodie\, and Sergei Grudinin. “HOPMA: Boosting protein functional dynamics with colored contact maps.” The Journal of Physical Chemistry B 125.10 (2021): 2577-2588.[3] Grudinin\, Sergei\, Elodie Laine\, and Alexandre Hoffmann. “Predicting protein functional motions: an old recipe with a new twist.” Biophysical journal 118.10 (2020): 2513-2525.[4] Hoffmann\, Alexandre\, and Sergei Grudinin. “NOLB: Nonlinear rigid block normal-mode analysis method.” Journal of chemical theory and computation 13.5 (2017): 2123-2134.
URL:https://www.scilifelab.se/event/the-current-state-of-modeling-protein-motions-from-physics-to-ai/
LOCATION:Online event via Zoom
CATEGORIES:Event
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20211011T151500
DTEND;TZID=Europe/Stockholm:20211011T163000
DTSTAMP:20260404T213918
CREATED:20210927T110517Z
LAST-MODIFIED:20211005T080643Z
UID:10000455-1633965300-1633969800@www.scilifelab.se
SUMMARY:The Svedberg seminar series: Prof.  Paolo Parini
DESCRIPTION:Theme Inflammation and Ageing\, Karolinska University Hospital\, \n\n\n\nDepartment of Laboratory Medicine and Department of Medicine \n\n\n\nKarolinska Institutet at Huddinge University Hospital\, \n\n\n\n\n\nLINK TO SEMINAR \n\n\n\n \n\n\n\n \n\n\n\n\n\n\n\n\n\nProf. Paolo Parini gained his MD degree in 1990 at the Universita’ di Bologna\, Italy. In 1994 he obtained his specialization in Gastroenterology and Hepatology (Universita’ di Bologna\, Italy). The same year Parini was registered as PhD-student at the Karolinska Institutet\, Sweden\, under the supervision of Prof Mats Rudling and Prof Bo Angelin. In 1999\, he obtained his PhD defending a thesis entitled “Hormonal regulation of hepatic cholesterol and lipoprotein metabolism: effects of estrogen and growth hormone” and since then his research activities are focused on the different aspect of lipoprotein metabolism in humans and in preclinical models. \n\n\n\nNetwork Medicine Approach to Atherosclerosis\n\n\n\nDuring the last several decades non-communicable diseases (NCDs) have dramatically increased deaths globally. One of the most prevalent NCD\, atherosclerotic cardiovascular disease (ASCVD) and cardiometabolic disease (CMD)\, are now major global health threats and socioeconomic burdens. Combined Hyperlipidemia (CH) is the most common form of hyperlipidemia and impacts longevity by promoting ASCVD\, CMD. Conventional ‘omics studies\, designed to find simple associations between genotype and phenotype in large datasets\, are inherently incapable of unraveling the complex pathobiology underlying diseases. Using network analysis\, we aim to describe the effects of the peripheral lipoprotein phenotypes of CH described in a multidimensional space by modules of functional interactions\, using patients from different existing cohorts to understand whether CH drives accelerated biological ageing\, estimated by analysis of the epigenome (DNA-methylation) in conjunction with specific ICD-10 diagnoses and treatments as a function of chronological age. We plan to integrate data of different nature [e.g.\, genetic\, epigenetic\, biochemistry\, national registries\, and electronic health record (EHR)\, and patient reported outcome measures (PROM) questionnaires]. As initial proof-of-concept\, we have created novel multi-source networks in which single-source analyses (i.e.\, liver transcriptomics and epigenomics) are integrated with biochemical parameters and lipoprotein functionality in combination with  Dr. Joseph Loscalzo´s human PPI Personal Protein I. Patients were from the Stockholm Study\, in non-obese\, normolipidemic\, gallstone patients (66% female) were randomized to a 4-week treatment with simvastatin 80 mg/day and ezetimibe 10 mg/day\, alone or in combination\, or to placebo. The first network mining has already indicated a constant and previously unknown interaction between a key gene in cholesterol metabolism and TMBIM6\, a transmembrane protein involved in autophagy and cancer information contained in the multi-source networks. Validation studies of this initial finding in going on in Soat2-only HepG2 cells\, a unique pre-clinical model which more closely resembles human lipoprotein metabolism created by us. \n\n\n\nHost: Olli Kallioniemi\, SciLifeLab Director
URL:https://www.scilifelab.se/event/the-svedberg-seminar-series-prof-paolo-parini/
LOCATION:Online event via Zoom
CATEGORIES:Event
ORGANIZER;CN="The Svedberg Seminar Series":MAILTO:thesvedberg@scilifelab.uu.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20211015T090000
DTEND;TZID=Europe/Stockholm:20211015T093000
DTSTAMP:20260404T213918
CREATED:20210921T171433Z
LAST-MODIFIED:20211014T114429Z
UID:10000450-1634288400-1634290200@www.scilifelab.se
SUMMARY:Clinical Talks: Playing your way to healthy life
DESCRIPTION:On October 15\, it’s our great pleasure to host Professor Emma Lundberg once again. This time she will focus her Talk on her innovative company Mindforce GameLab. With the Fig platform\, patients can via gamification transform into “playtients”\, people with medical conditions who enjoy playing games with a purpose to establish healthy habits. Fig guides you on the journey to better health\, including improved behavioral administration of medicals for intended and sustainable use. \n\n\n\nEmma Lundberg SciLifeLab. \nFoto © Daniel Roos\n\n\n\nEmma is a Professor in cell biology proteomics at KTH Royal Institute of Technology\, Sweden\, and Director of the Cell Atlas\, part of the Human Protein Atlas program. She spent two and half sabbatical years as visiting Associate Professor at Stanford School of Medicine and the Chan-Zuckerberg Biohub. In the interface between bioimaging\, proteomics and artificial intelligence her research aims to define the spatiotemporal organization of the human proteome at a subcellular level\, with the goal to understand how variations and deviations in protein expression patterns can contribute to cellular function and disease.  \n\n\n\nShe also has a keen interest\, passion\, and fascination in the use of gaming for science and health applications. This led Emma to start her own company in 2017\, Skellefteå based Mindforce Game Lab\, with the goal to unleash the powerful potential gamification could offer medical healthcare. Simply phrased\, medicines will not work if people do not take them. Despite this\, only every other person takes their medication as prescribed. This is a fundamental challenge for treating many chronic diseases\, in terms of patient outcomes\, as well as the overall burden on healthcare systems. Although there are products that help patients with extrinsic motivations\, such as reminders and notifications\, Mindforce Game Lab focuses on intrinsic motivations; designing games that build in feelings of companionship\, belonging and purpose. Patients learn how healthy routines\, such as sleeping well\, eating well\, exercising regularly\, and adhering to prescribed medication\, can improve feelings of well-being. This builds an inner driving force to want to change behaviour and to maintain a healthy lifestyle. In late 2020 Mindforce Game Lab joined the AstraZeneca BioVentureHub and relocated the development team to Gothenburg. \n\n\n\nRegister to receive zoom link\n\n\n\n\n\n\n\nAfter our recent planning hiatus\, we now have the great pleasure to announce that “Clinical Talks” has been renewed for yet another exciting\, innovative\, and enlightening season. This season will focus on sustainable innovations within Life Sciences\, that have the potential to contribute to a better climate friendly future for our future generations. Also new this year is that the seminar is co-organized in a collaboration between SciLifeLab and KI Innovations. \n\n\n\nRead more
URL:https://www.scilifelab.se/event/playing-your-way-to-healthy-life/
LOCATION:Online event via Zoom
CATEGORIES:Event
ATTACH;FMTTYPE=image/jpeg:https://www.scilifelab.se/wp-content/uploads/2021/09/ClinicalTalks_Emma-Lundberg_1024-1.jpg
ORGANIZER;CN="Clinical Talks":MAILTO:precisionmedicine@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20211015T093000
DTEND;TZID=Europe/Stockholm:20211015T113000
DTSTAMP:20260404T213918
CREATED:20210922T144136Z
LAST-MODIFIED:20210922T173935Z
UID:10000451-1634290200-1634297400@www.scilifelab.se
SUMMARY:Virtual coffee drop in session - COVID-19 Data &  Code Reuse Competition 
DESCRIPTION:Location: Online via Zoom\n\n\n\nThe Swedish COVID-19 Data Portal invites you to join us for a Virtual coffee drop-in session and discussion about COVID-19 Data & Code Reuse Competition submissions. Take this opportunity to get support and ask questions about your ideas\, planned or  already started project for the competition. Drop-in for a chat with us and other participants\, we look forward to meet you. \n\n\n\nAbout the COVID-19 Data & Code Reuse Competition \n\n\n\nThe Swedish COVID-19 Data Portal invites researchers and general public to take part in the COVID-19 Data & Code Reuse Competition. Participants should complete small-scale projects that make use of publicly shared data and/or code to combat the COVID-19 pandemic or any future pandemics. \n\n\n\nWe welcome various types of project. The projects could\, for example\, involve the re-analysis of existing publicly available data using a different method\, or focus on a different aim\, or reuse publicly shared code to process a new set of data. Other possibilities include projects that produce individual visualizations\, dashboards presenting publicly shared data in a novel way or web-services devoted to data and analysis. The emphasis of the projects submitted should be to maximize the utility of existing data and/or code. \n\n\n\n\n\n\n\nRegister before October 14 to receive the Zoom link and allow planning of resources \n\n\n\nContact: SciLifeLab Data Centre\, datacentre@scilifelab.se \n\n\n\nRegister here
URL:https://www.scilifelab.se/event/virtual-coffee-drop-in-session-covid-19-data-code-reuse-competition/
LOCATION:Online event via Zoom
CATEGORIES:Event
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20211018T151500
DTEND;TZID=Europe/Stockholm:20211018T161500
DTSTAMP:20260404T213918
CREATED:20210916T151516Z
LAST-MODIFIED:20210927T100311Z
UID:10000448-1634570100-1634573700@www.scilifelab.se
SUMMARY:The Svedberg seminar series: Ass. Prof. Prashant Singh
DESCRIPTION:SciLifeLab Fellow at Uppsala University \n\n\n\nLINK TO SEMINAR \n\n\n\n\n\n\n\n\n\nPrashant Singh is a SciLifeLab fellow and Assistant Professor hosted by the Division of Scientific Computing\, Department of Information Technology\, Uppsala University. His research interests involve developing machine learning and optimization methods to enable fast\, data-efficient analysis and processing of scientific data\, particularly in the domain of life sciences. \n\n\n\nScalable Likelihood-Free Parameter Inference of Stochastic Biochemical Reaction Networks\n\n\n\nAbstract: Parameter inference of stochastic time series models\, such as gene regulatory networks in the likelihood-free setting is a challenging task\, particularly when the number of parameters to be inferred is large. Recently\, data-driven machine learning models (neural networks in particular) have delivered encouraging results towards addressing the scalability\, efficiency and parameter inference quality of the likelihood-free parameter inference pipeline. In particular\, this talk will present a detailed discussion on neural networks as trainable\, expressive and scalable summary statistics of high-dimensional time series for parameter inference tasks. \n\n\n\nReference: \n\n\n\nM. Akesson\, P. Singh\, F. Wrede and A. Hellander\, “Convolutional Neural Networks as Summary Statistics for Approximate Bayesian Computation\,” in IEEE/ACM Transactions on Computational Biology and Bioinformatics\, doi: 10.1109/TCBB.2021.3108695. \n\n\n\nHost: Prof. Elisabeth Larsson\, Uppsala University
URL:https://www.scilifelab.se/event/the-svedberg-seminar-series-assoc-prof-prashant-singh/
LOCATION:Online event via Zoom
CATEGORIES:Event
ORGANIZER;CN="The Svedberg Seminar Series":MAILTO:thesvedberg@scilifelab.uu.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20211019T143000
DTEND;TZID=Europe/Stockholm:20211022T183000
DTSTAMP:20260404T213918
CREATED:20210524T143123Z
LAST-MODIFIED:20211007T121821Z
UID:10000392-1634653800-1634927400@www.scilifelab.se
SUMMARY:International Advisory Board meeting 2021
DESCRIPTION:The site visit has become a digital Zoom meeting. We welcome the International Advisory Board (IAB) of SciLifeLab to a 4-day meeting on October 19-22\, 2021. During the meeting\, we will discuss and seek guidance about SciLifeLab and its future plans. A background report\, prepared by the SciLifeLab management\, is sent to the IAB members. \n\n\n\n \n\n\n\n\nIAB Program\n\n\n\n\n\n\n\n\n\n\n\n\nPicture taken during the IAB visit in 2019. Left to right\, back to front row: Svante Pääbo\, Jonathan Knowles\, Yoshihide Hayashizaki\, Jo Bury\, Carl-Henrik Heldin\, Jan Ellenberg\, Annika Jenmalm Jensen\, Olli Kallioniemi\, Sarah Teichmann\, Sirpa Jalkanen\, Janet Jansson and Sören Brunak.
URL:https://www.scilifelab.se/event/international-advisory-board-meeting-2021/
CATEGORIES:Event
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20211021T143000
DTEND;TZID=Europe/Stockholm:20211021T151500
DTSTAMP:20260404T213918
CREATED:20211005T093455Z
LAST-MODIFIED:20211005T093615Z
UID:10000461-1634826600-1634829300@www.scilifelab.se
SUMMARY:[Big Talks] – Transposon Genomics — From Single Loci To Single Cells
DESCRIPTION:Invited speaker \n\n\n\nMolly Gale Hammell\, Associate Professor\, Cold Spring Harbor Laboratory\, USA \n\n\n\n \n\n\n\nAbstract\n\n\n\nTransposable Elements (TEs) are sequences in the human genome that have (or once had) the ability to mobilize from one location in the genome to another. Most of the TEs that currently exist in the human genome are fixed and unable to mobilize\, but many of these sequences have some residual level of functionality. These residual functions might include: the ability to bind DNA- or RNA-binding factors and act as regulatory elements\, the ability to generate RNA transcripts\, and/or the ability to encode proteins. Because TEs are extremely abundant in the human genome\, covering nearly 45% of the sequence space\, active TEs can have a large\, and often deleterious\, impact on host cell function. Multiple studies have shown aberrant elevation of TE expression in aging-associated diseases\, such as neurodegeneration and cancer. However\, establishing a causal role for TE activity in these contexts requires tracking down the individual TE loci that are active\, and distinguishing these from the thousands of other TE loci that are silent and/or non-functional. This is still an unsolved problem in the field of transposon genomics\, but new tools and technologies are making the problem more tractable. These include long-read technologies\, and improved statistical methods for analyzing TE expression and integrating TE multi-omics datasets. Once aberrantly active TE loci are identified\, it’s often important to know which cell type is harboring these activated TEs\, and whether certain cells are more vulnerable to TE activity than others. Integrating TE expression analysis into single-cell genomics workflows is crucial to understanding how these elements contribute to human disease. I will present recent results from my lab that tackle these issues in the context of neurodegeneration\, where elevated transposons are thought to contribute to neurotoxicity\, and may also contribute to neuroinflammation.  \n\n\n\nBiography\n\n\n\n\n\n\n\nThe Gale Hammell lab uses a combination of computational and experimental methods to understand how gene regulatory networks are perturbed in human disease. This includes an emphasis on developing novel tools for the statistical analysis of high-throughput data\, developing novel algorithms for modeling the flow of signals through genetic pathways\, and importantly\, testing these models using the tools of molecular genetics. One particular focus of the M. Hammell lab is to apply these novel statistical analysis methods to better understand how transposable elements are normally controlled. Mounting evidence has implicated transposon activity in a host of human diseases\, with particular evidence for activation in several neurodegenerative diseases\, including Amyotrophic lateral sclerosis (ALS)\, Fronto-Temporal Dementia (FTD)\, and Alzheimer’s Disease (AD). By combining the power of systems-level\, high-throughput data analysis with patient-derived ALS\, FTD\, and AD tissue samples\, the lab aims to better understand how these viral-like sequences contribute to cell death and disease. \n\n\n\n\n\n\n\nHost: Louella Vasquez\, NBIS Lund (louella.vasquez@scilifelab.se) \n\n\n\nDate: October 21\, 14:30 – 15:15 CET online on YouTube \n\n\n\nBroadcast link (live event): SBW YouTube channelThe talk will also be available afterwards on the SciLifeLab YouTube channel.More information about the Swedish Bioinformatics Workshop here.
URL:https://www.scilifelab.se/event/big-talks-transposon-genomics-from-single-loci-to-single-cells/
CATEGORIES:Event
ORGANIZER;CN="Swedish Bioinformatics Workshop":MAILTO:louella.vasquez@scilifelab.se
LOCATION:https://www.scilifelab.se/event/big-talks-transposon-genomics-from-single-loci-to-single-cells/
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BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20211021T170000
DTEND;TZID=Europe/Stockholm:20211021T173000
DTSTAMP:20260404T213918
CREATED:20210928T135950Z
LAST-MODIFIED:20211005T094033Z
UID:10000457-1634835600-1634837400@www.scilifelab.se
SUMMARY:Clinical Talks: Writing the Future
DESCRIPTION:Writing the Future\n\n\n\nOn October 21\, Dr. Emily Leproust will talk about her mission with co-founding Twist Bioscience\, and how their revolutionary oligosynthesis plattform is writing the future with DNA.  \n\n\n\nTwist Bioscience’s innovative silicon-based DNA Synthesis Platform is empowering our customers to realise their research goals faster. Twist offers DNA synthesis at an unmatched scale and price point\, without compromising on precision or quality. Here we discuss how DNA synthesis at scale can make traditional molecular biology approaches redundant in labs working with plasmid vectors; can power massive\, explicit diversity in CRISPR and antibody variant libraries; and can underpin NGS Target Enrichment Solutions with exceptional performance and unmatched speed in customisation. We’ll look at how these tools are helping drive innovation in a variety of research and application areas including cancer research\, drug discovery\, infectious disease and even data storage. \n\n\n\nAs an early pioneer in the high-throughput synthesis and sequencing of DNA\, Dr. Leproust is disrupting markets to enable the exponential growth of DNA-based applications including chemicals/materials\, diagnostics\, therapeutics\, food and digital data storage. In 2020\, BIO presented her with the Rosalind Franklin Award for Leadership. Foreign Policy named her one of their 100 Leading Global Thinkers and Fast Company named her one of the Most Creative People in Business. Prior to Twist Bioscience\, she held escalating positions at Agilent Technologies where she architected the successful SureSelect product line that lowered the cost of sequencing and elucidated mechanisms responsible for dozens of Mendelian diseases. She also developed the Oligo Library Synthesis technology\, where she initiated and led product and business development activities for the team. Dr. Leproust designed and developed multiple commercial synthesis platforms to streamline microarray manufacturing and fabrication. She serves on the Board of Directors of CM Life Sciences and is a co-founder of Petri\, an accelerator for start-ups at the forefront of engineering and biology. Dr. Leproust has published over 30 peer-reviewed papers – many on applications of synthetic DNA\, and is the author of numerous patents. She earned her Ph.D. in Organic Chemistry from University of Houston and her M.Sc. in Industrial Chemistry from the Lyon School of Industrial Chemistry. \n\n\n\nregistration\n\n\n\n\n\n\n\nSeason 5\, will be held September until December 2021 with scheduled Talks\, during Friday mornings 09-09:30 am via ZOOM (with some time-zone friendly adjustments for our international speakers). Each session consists of a talk given by our invited speaker followed by Q&A. The seminar is an open educational seminar series for our ever-expanding Life Science community. \n\n\n\nAfter our recent planning hiatus\, we now have the great pleasure to announce that “Clinical Talks” has been renewed for yet another exciting\, innovative\, and enlightening season. This season will focus on sustainable innovations within Life Sciences\, that have the potential to contribute to a better climate friendly future for our future generations. Also new this year is that the seminar is co-organized in a collaboration between SciLifeLab and KI Innovations. \n\n\n\nRead more
URL:https://www.scilifelab.se/event/clinical-talks-writing-the-future/
LOCATION:Online event via Zoom
CATEGORIES:Event
ATTACH;FMTTYPE=image/jpeg:https://www.scilifelab.se/wp-content/uploads/2021/09/ClinicalTalks_Season5_twitter_1024.jpg
ORGANIZER;CN="Clinical Talks":MAILTO:precisionmedicine@scilifelab.se
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BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20211026T130000
DTEND;TZID=Europe/Stockholm:20211026T160000
DTSTAMP:20260404T213918
CREATED:20210928T124945Z
LAST-MODIFIED:20211018T141735Z
UID:10000456-1635253200-1635264000@www.scilifelab.se
SUMMARY:DNP inauguration ceremony
DESCRIPTION:We are very happy to announce the unique collaboration between AstraZeneca and University of Gothenburg on advanced NMR technology\, manifested in the inauguration ceremony of our new DNP-NMR instrument! \n\n\n\nWelcome to the DNP inauguration ceremony to celebrate the DNP-NMR instrument investment at the Swedish NMR Centre\, University of Gothenburg! \n\n\n\nThe ceremony will take place between 13.00 – 16.00 on October 26 in lecture hall Birgit Thilander\, Medicinaregatan 3\, Gothenburg. \n\n\n\nInvited guest speaker professor Lyndon Emsley from EPFL Lausanne will close the ceremony by giving a lecture between 15.00 – 16.00. \n\n\n\nPlease respond before October 16. \n\n\n\nregistration\n\n\n\nProgram\n\n\n\n13.00Welcome remarksWelcome – Göran Karlsson\, Director Swedish NMR Centre\, and Staffan Schantz\, APS AstraZenecaGothenburg ecosystem view – Matti Ahlqvist\, AstraZeneca Gothenburg Executive Site DirectorPharmaceutical development – Piet van den Oetelaar\, Head OPD/AstraZenecaUniversity Research Infrastructures – Göran Hilmersson\, Dean\, The Faculty of Science\, University of Gothenburg.13.45Tour to the new DNP-NMR instrumentArthur Pinon\, SNC14.30Light snacks & refreshments15.00Structure Activity Relations in Materials from DNP-NMRLyndon Emsley\, EPFL Lausanne16.00Closing\n\n\n\n \n\n\n\nOn behalf of the inauguration ceremony team\, \n\n\n\nStaffan Schantz\, AstraZeneca\, Göran Karlsson\, University of Gothenburg\, Ulrika Brath\, University of Gothenburg Nina Berg\, AstraZeneca 
URL:https://www.scilifelab.se/event/dnp-inauguration-ceremony/
LOCATION:Birgit Thilander Lecture Hall\, Medicinaregatan 3\, Göteborg
CATEGORIES:Event
ATTACH;FMTTYPE=image/jpeg:https://www.scilifelab.se/wp-content/uploads/2021/09/image001.jpg
ORGANIZER;CN="Swedish NMR Centre":MAILTO:info@nmr.gu.se
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