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DTSTART;TZID=Europe/Stockholm:20260210T160000
DTEND;TZID=Europe/Stockholm:20260210T173000
DTSTAMP:20260407T112406
CREATED:20251222T114557Z
LAST-MODIFIED:20251222T114558Z
UID:10001691-1770739200-1770744600@www.scilifelab.se
SUMMARY:Building and sharing AI applications within ecology and biodiversity
DESCRIPTION:This workshop is part of the SBDI Days 2026. In order to take part\, you need to register for the main event and select this workshop. \n\n\n\nTitle: Building and sharing AI applications within ecology and biodiversity. \n\n\n\nOrganizer: SciLifeLab Data Centre (AI Data Engineers from the SciLifeLab Serve team). \n\n\n\nWhere and when: February 10\, 2026 at 16:00-17:30 at the Museum of Natural History in Stockholm. Address: Frescativägen 40\, 114 18 Stockholm. \n\n\n\nAbstract: As more researchers in ecology and biodiversity build machine learning models\, it is important to find ways to make these models useful for the researcher community or general public. One way to do this is to share the models as web applications with an easy-to-use interface. Users of the models can then adjust parameters or submit their own input and see the result generated by the underlying model. This tutorial is aimed at PhDs and researchers working within ecology and biodiversity who work with machine learning models but do not have the skills to build applications for the web. During the tutorial we will start from a trained model and demonstrate step by step how you can create a graphical user interface for your application\, prepare it for deployment\, and make it available on the web with a URL. We will demonstrate the use of specific tools which make this process easy and doable in under an hour. \n\n\n\nExpected outcomes: Participants will have an overview of various open-source tools for creating applications out of machine learning models. Furthermore\, they will have practices creating an application using one such tool or perhaps already have a demo of an application with their own model. Participants will have knowledge about options for hosting their applications and making them available to the general public or to colleagues. \n\n\n\nRegister to join the event\n\n\n\nFor questions about the events please contact the organizing team by emailing  serve@scilifelab.se  \n\n\n\nContact information: serve@scilifelab.se
URL:https://www.scilifelab.se/event/building-and-sharing-ai-applications-within-ecology-and-biodiversity/
CATEGORIES:Event
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20260210T083000
DTEND;TZID=Europe/Stockholm:20260211T170000
DTSTAMP:20260407T112406
CREATED:20251121T085203Z
LAST-MODIFIED:20251205T082250Z
UID:10001672-1770712200-1770829200@www.scilifelab.se
SUMMARY:SBDI Days 2026 -Artificial Intelligence in Ecology and Biodiversity Research
DESCRIPTION:Artificial Intelligence is no longer just a tool. It is becoming a vital partner in the quest to understand and protect biodiversity. SBDI Days 2026 will explore this transformative partnership under the theme: AI and Biodiversity: a Perfect Pair! \n\n\n\nThe Planetary Biology Strategic Area is pleased to team up with the Swedish Biodiversity Data Infrastructure (SBDI) for this event that dives deep into the future of Ecology and Biodiversity Research. \n\n\n\nHighlights of the program:  \n\n\n\n\nTalks on using AI in Biodiversity Research and monitoring\, pros\, cons and ethics\n\n\n\nPoster sessions\n\n\n\nWorkshops on FAIR data principles\, tools to integrate biodiversity monitoring data from different platforms\, building AI applications within ecology and biodiversity\, and using eDNA data within the SBDI. \n\n\n\n\nEarly career researchers are warmly encouraged to present their work.  \n\n\n\nAbstract submission for poster or oral presentation are open till December 15\, 2025. \n\n\n\nCheck out the conference website to dive into the program and register \n\n\n\nConference website
URL:https://www.scilifelab.se/event/sbdi-days-2026-artificial-intelligence-in-ecology-and-biodiversity-research/
LOCATION:Swedish Museum of Natural History\, Frescativägen 40\, Stockholm\, Stockholm\, 114 18\, Sweden
CATEGORIES:Event
ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2025/11/SBDI-days-2026_SLLweb-1.png
ORGANIZER;CN="SciLifeLab Planetary Biology Strategic Area":MAILTO:anabella.aguilera@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20260209T150000
DTEND;TZID=Europe/Stockholm:20260209T160000
DTSTAMP:20260407T112406
CREATED:20260123T120235Z
LAST-MODIFIED:20260126T114030Z
UID:10001733-1770649200-1770652800@www.scilifelab.se
SUMMARY:PULSE Challenge: From Serendipity to Design Principles Molecular Glues as a Prelude to RIPTACs
DESCRIPTION:Traditionally viewed as inhibitors\, small molecules have evolved through the discovery of molecular glues—compounds that create function by stabilizing protein-protein interactions. This shift from serendipitous discovery to “induced proximity” has expanded the druggable proteome and redefined how we control cellular behavior. \n\n\n\nThis talk traces the evolution of molecular glues\, framing them as versatile proximity-inducing agents rather than just degradation tools. I emphasize their impact on our understanding of protein surfaces and cellular organization. The second half introduces Regulated Induced Proximity Targeting Chimeras (RIPTACs). I highlight HLD-0915\, a novel RIPTAC targeting prostate cancer. In preclinical models\, HLD-0915 demonstrated tumor regression and a favorable therapeutic index\, even in drug-resistant cases. Finally\, I present Phase 1 data from mCRPC patients\, showing strong tolerability and encouraging anti-tumor activity in heavily pretreated populations. \n\n\n\nHost: Vasanthanathan PoongavanamModerator: Per Arvidsson \n\n\n\nThe seminar series PULSE Challenge is connected to the MSCA co-funded* postdoctoral program SciLifeLab PULSE\, that will train 48 future leaders in life sciences. The program focuses on innovative\, fundamental and translational research carried out in supportive and diverse academic and industrial environments\, preparing postdocs with necessary skills for long-term career sustainability. Click HERE to find out more about SciLifeLab PULSE \n\n\n\n\n\n\n\nOn-line event via Zoom \n\n\n\nRegister Here\n\n\n\n\n\n\n\n\n\n\n\n\n\nPresenter: Dr. Muthukumaran Venkatachalapathy  \n\n\n\nBiography:Dr. Muthukumaran Venkatachalapathy is currently an Associate Research Scientist in the Department of Chemistry at Yale University (with Professor Craig Crews and Prof David Spiegel). With a strong background in Chemical Biology\, he earned his Ph.D. from the Max Planck Institute in Dortmund\, Germany. His research interests focus on developing novel chemical biology modalities for targeted protein degradation and therapeutic discovery
URL:https://www.scilifelab.se/event/pulse-challenge-from-serendipity-to-design-principles-molecular-glues-as-a-prelude-to-riptacs/
LOCATION:Online event via Zoom
CATEGORIES:Event
ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2025/02/Bild1-e1770905208628.png
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20260205T140000
DTEND;TZID=Europe/Stockholm:20260205T150000
DTSTAMP:20260407T112406
CREATED:20260114T123445Z
LAST-MODIFIED:20260114T123447Z
UID:10001718-1770300000-1770303600@www.scilifelab.se
SUMMARY:Automated morphological profiling at scale for drug discovery\, target identification and drug repurposing
DESCRIPTION:Welcome to a seminar with Shantanu Singh in the Chemical Biology Seminar Series!\n\n\n\n“Automated morphological profiling at scale for drug discovery\, target identification and drug repurposing”Shantanu Singh\, Ph.D. & Senior Group LeaderBroad Institute \n\n\n\nWe will meet up with individuals who do not have access to SciLifeLab in the reception at 13.50.
URL:https://www.scilifelab.se/event/automated-morphological-profiling-at-scale-for-drug-discovery-target-identification-and-drug-repurposing/
LOCATION:Air&Fire\, SciLifeLab Stockholm\, Tomtebodavägen 23A\, Solna\, Sweden
CATEGORIES:Event
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20260205T100000
DTEND;TZID=Europe/Stockholm:20260205T110000
DTSTAMP:20260407T112406
CREATED:20251222T143419Z
LAST-MODIFIED:20251222T143932Z
UID:10001692-1770285600-1770289200@www.scilifelab.se
SUMMARY:Webinar: Current state of AI agents in life sciences
DESCRIPTION:Title: Current state of AI agents in life sciences \n\n\n\nSpeaker: Mahbub Ul Alam (AI Data Engineer\, SciLifeLab Data Centre) \n\n\n\nWhere and when: February 5\, 2026 at 10:00-11:00 Stockholm time\, online. Registration is open till February 5 at 9:00. \n\n\n\nAbstract: AI agents are emerging as autonomous systems that orchestrate scientific workflows by interacting with digital tools and data sources. These have various implications for life science research. They can\, for example\, simplify complex analyses by automating data integration\, run computational models\, and coordinate experimental steps\, making research pipelines more efficient and reproducible. In this online webinar we will give an introduction into what AI agents are\, discuss their potential in life sciences\, and give an overview of the most recent popular AI agent platforms that have emerged in the past months/year. \n\n\n\nThis is an introduction-level webinar where we will give a basic overview of AI agents. For more in-depth discussion and hands-on workshop consider\, for example\, this on-site workshop. \n\n\n\nTarget audience: Anyone working in or with life science research is welcome. \n\n\n\nRegister to join the event\n\n\n\nFor questions about the events please contact the organizing team by emailing datacentre@scilifelab.se  \n\n\n\nScientific lead: Prof. Ola Spjuth\, SciLifeLab Data Centre and Uppsala University \n\n\n\nContact information: datacentre@scilifelab.se
URL:https://www.scilifelab.se/event/webinar-ai-agents-in-life-sciences/
LOCATION:Online event via Zoom
CATEGORIES:Event
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20260205T090000
DTEND;TZID=Europe/Stockholm:20260205T103000
DTSTAMP:20260407T112406
CREATED:20260129T151447Z
LAST-MODIFIED:20260130T083913Z
UID:10001739-1770282000-1770287400@www.scilifelab.se
SUMMARY:User meeting for your multi-modal research projects
DESCRIPTION:Boost your research — Book a private SciLifeLab planning and feedback session for your multi-modal research projects! \n\n\n\nOnce we have received your registration\, you will be sent the link to the online meeting. \n\n\n\nRegister here\n\n\n\nDate: February 5 9.00 – 10.30 Registration deadline: January 30 \n\n\n\nMultimodal molecular profiling and novel computational methods are transforming life science research\, but also pose new challenges in study design\, project resource planning and data management. SciLifeLab is a national resource of unique technologies and expertise available to life scientists\, in areas such as biomedicine\, ecology and evolution\, aiming to bring scientists together across traditional boundaries and foster collaborations with industry\, health care\, public research organizations and international partners. \n\n\n\nThe first Thursday of every month at 9.00 (except July and August)\, SciLifeLab offers an opportunity to jointly meet with representatives across the SciLifeLab service platforms\, to get feedback and help to plan\, design\, and refine new or ongoing multimodal research projects. Your project plans are discussed privately and remain confidential\, and information will not be shared outside of the service platforms. Note that for most studies\, follow-up meetings will be needed\, but our aim for these meetings is to provide an easy-access entry point for an overarching planning of multimodal studies. \n\n\n\nFor studies focusing on a single technology only\, please primarily contact our service platforms directly as described at the SciLifeLab homepage. \n\n\n\nTo make the best out of the allotted time\, we ask you to provide some background information about your project\, to help us ensure that the relevant experts are available to discuss your study.
URL:https://www.scilifelab.se/event/user-meeting-for-your-multi-modal-research-projects-4/
CATEGORIES:Event
ATTACH;FMTTYPE=image/jpeg:https://www.scilifelab.se/wp-content/uploads/2026/01/AdobeStock_1081766437-scaled-1.jpeg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20260203T110000
DTEND;TZID=Europe/Stockholm:20260203T120000
DTSTAMP:20260407T112406
CREATED:20251218T145246Z
LAST-MODIFIED:20260107T093948Z
UID:10001685-1770116400-1770120000@www.scilifelab.se
SUMMARY:From Scientific Ideals to Practical Open Science: How reporting on study limitations can diminish Avoidable Research Waste
DESCRIPTION:What can a sociological framework from the mid-20th century teach us about today’s open-science movement? Surprisingly much.In this virtual seminar\, we revisit Robert Merton’s CUDOS framework—Communalism\, Universalism\, Disinterestedness\, and Organized Skepticism—and explore why these four principles continue to shape how we think about responsible and transparent research. The presentation will place special emphasis on organized skepticism: what it means in practice\, why it is crucial for research credibility\, and how fostering a culture of constructive critique can directly reduce avoidable research waste. The talk will also introduce practical examples of how these ideals can be operationalized today. You’ll hear about work on the automatic detection of study-limitation statements in scientific texts\, its implementation in the research-quality tool ScreenIT\, and how such tools can support reproducibility and stronger research assessment. The seminar will end with findings from a recent study on researchers’ adherence to a 14-item checklist for responsible and open research between 2020 and 2024.This session will appeal to anyone interested in: \n\n\n\n\nresearch transparency and rigor\n\n\n\nthe philosophical roots of open science\n\n\n\npractical tools for improving research quality\n\n\n\nshaping a scientific culture aligned with modern open-science values\n\n\n\n\nPresenter: Gerben ter Riet MD PhD – Amsterdam University of Applied Sciences (AUAS) – Clinical epidemiologist\, Open Science Advisor\, Member of the Committee for Research Integrity (at AUAS)\, and advisory board member of the Netherlands Research Integrity Network (NRIN). \n\n\n\nRecording: Recording will be available after the event on: https://www.youtube.com/@SciLifeLabTalksTraining Slides: The slides will be available after the event. \n\n\n\nMore information\n\nThis event is part of the SciLifeLab Open Science seminar series\, an event series by the SciLifeLab Data Centre and NBIS joint Data Management team.The goal of the events in this seminar series is to provide interesting interactive seminars around topics related to Research Data Management and Open Science in general\, and to foster discussions around best practices. \n\n\nResearch Data Management (RDM) concerns the organization\, storage\, preservation\, and sharing of data that is collected and analyzed during a research project. Proper planning and management of research data will make project management easier and more efficient while projects are being performed. It also facilitates sharing and allows others to validate as well as reuse the data.Open Science is a set of principles and practices that aim to make scientific research from all fields accessible to everyone for the benefits of scientists and society as a whole. Open science is about making sure not only that scientific knowledge is accessible but also that the production of that knowledge itself is inclusive\, equitable and sustainable. \n\n\nThe events are open to everyone working at or affiliated with a Swedish research institute or university. We welcome all researchers\, educational professionals\, staff\, RDM professionals\, and others with an interest in life sciences\, from all university levels. The events are informal and inclusive\, so feel welcome to join and participate in our interesting discussions! \n\n\nThe events will be recorded and published openly after the seminars on the SciLifeLab YouTube channel. The slides will be made available at our SciLifeLab Data Repository. More information about SciLifeLab Data Centre and NBIS joint Open Science seminar series: https://www.scilifelab.se/data/scilifelab-data-management-seminar-series/ \n\n\nIf you have suggestions for topics or presentations\, please contact us at data-management@scilifelab.seFor more information or inquiries\, please contact us at  data-management@scilifelab.se
URL:https://www.scilifelab.se/event/openscience-research-integrity/
CATEGORIES:Event
ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2024/02/DC_seminar-series_background1-1.png
ORGANIZER;CN="Open Science Seminar Series":MAILTO:data-management@scilifelab.se
LOCATION:https://uu-se.zoom.us/j/65990273341?from=addon
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20260202T130000
DTEND;TZID=Europe/Stockholm:20260202T154500
DTSTAMP:20260407T112406
CREATED:20251218T113355Z
LAST-MODIFIED:20260114T112016Z
UID:10001684-1770037200-1770047100@www.scilifelab.se
SUMMARY:Research seminar for Associate Senior Lecturer\, SciLifeLab Fellow position in inflammation research
DESCRIPTION:Welcome to the seminars and discussions with candidates for the SciLifeLab Fellow position in inflammation research at Uppsala University. \n\n\n\nDate: February 2\, 2026 \n\n\n\nTime: 13:00 – 15:30 \n\n\n\nLocation: The Triple room in SciLifeLab Navet\, Entrance C11 at BMC\, Husargatan 3\, Uppsala. Or Zoom. \n\n\n\nOrganized by the SciLifeLab Uppsala University Committee \n\n\n\nRegistration\n\n\n\nPlease register to reserve a seat onsite or get the Zoom link to attend online. \n\n\n\nJoin the Zoom meeting by following the “Link to online event” in the Confirmation email. We will also send an e-mail reminder the day before the event with a button to “Join the Zoom meeting”. \n\n\n\nZoom attendees: You will be placed in a waiting room until the host opens the meeting. You will be muted and off camera upon entry. We kindly ask participants to remain muted during the presentations and to submit questions in the Q&A field. The Host will address questions after each presentation.  \n\n\n\nRegistration\n\n\n\nProgram\n\n\n\n13:00   Welcome\, Hosts Prof. Anna Dimberg and Prof. Aristidis Moustakas \n\n\n\n13:05  Expanding Kidney-Resident Bregs In Vivo: A New Level on Kidney Inflammation\, Kailash Singh \n\n\n\n13:40 Precision Targeting of Inflammation Beyond Corticosteroids\, Aida Paivandy \n\n\n\n14:15 Short break \n\n\n\n14:25 Restoring immune tolerance in autoimmunity: autoreactive B cells and redox-controlled cellular strategies\, Mike Aoun \n\n\n\n15:00 Differential immune responses in Necrotizing Soft Tissue infections\, Laura Palma Medina \n\n\n\n15:30 Summary of the research seminars\,  Prof. Aristidis Moustakas \n\n\n\nProgram2.0_260202_Fellow position seminarDownload
URL:https://www.scilifelab.se/event/research-seminar-for-associate-senior-lecturer-scilifelab-fellow-position-in-inflammation-research/
LOCATION:Navet\, SciLifeLab Uppsala\, SciLifeLab Uppsala\, BMC C11\, Husargatan 3\, Uppsala\, 75237\, Sweden
CATEGORIES:Event
ATTACH;FMTTYPE=image/jpeg:https://www.scilifelab.se/wp-content/uploads/2025/10/Navet-Uppsala-entrance-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20260130T130000
DTEND;TZID=Europe/Stockholm:20260130T143000
DTSTAMP:20260407T112406
CREATED:20241220T095502Z
LAST-MODIFIED:20260128T152020Z
UID:10001421-1769778000-1769783400@www.scilifelab.se
SUMMARY:Information seminar on KAW/SciLifeLab Proof of Concept call for grants 2026
DESCRIPTION:The 4th call for KAW/SciLifeLab Proof of Concept grants in Life Science is open for applications! \n\n\n\nThe purpose of the Proof of Concept grant is to bridge the gap from academic research to innovations in life science. The grant gives researchers the opportunity to develop their early-stage discoveries towards validated methods\, products or processes and  provides the opportunity to carry out activities that validate and accelerate the development of the project and prepare for innovation and commercialization. \n\n\n\nWatch the seminar below to learn more about the call. ↓ \n\n\n\nRegister to the Seminar\n\n\n\nProgram\n\n\n\n13.00The KAW/SciLifeLab Proof of Concept grants in Life Science\, Olli Kallioniemi\, Professor of Molecular Precision Medicine\, KI\, Lilian Wikström\, KAW13.20Project presentation – Marie Jeansson\, KITherapeutic intervention to slow progression of chronic kidney disease13.40Project presentation – Pål Stenmark\, Stockholm UniversityInnovative therapeutic toxins for the treatment of neuromuscular disorders14.00Open discussionModerator – Isolde Palombo\, KTH\n\n\n\nApplication period\n\n\n\nCall opens: January 13\, 2026Call closes: February 20\, 2026 at 13:00 \n\n\n\nRead more about the Call
URL:https://www.scilifelab.se/event/information-seminar-on-kaw-scilifelab-proof-of-concept-call-for-grants-2026/
LOCATION:Online event via Zoom
CATEGORIES:Event
ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2025/12/Proof-of-Concept_bulb-in-center.png
ORGANIZER;CN="SciLifeLab Event":MAILTO:events@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20260130T120000
DTEND;TZID=Europe/Stockholm:20260130T130000
DTSTAMP:20260407T112406
CREATED:20260114T083003Z
LAST-MODIFIED:20260114T084059Z
UID:10001717-1769774400-1769778000@www.scilifelab.se
SUMMARY:Calls for new project support in Chemical Biology and Drug Discovery
DESCRIPTION:The Chemical Biology Unit (CBCS) and the Drug Discovery and Development (DDD) platform at SciLifeLab have calls out for projects. \n\n\n\nCBCS is seeking projects in Chemical Biology that include assay development for small-molecule screening and profiling\, as well as enabling chemistry.  \n\n\n\nFor more information\, please visit www.cbcs.se. \n\n\n\nThe DDD platform is looking for new project proposals for drug discovery. All therapeutic modalities that can be developed in collaboration with the DDD platform at SciLifeLab are of interest\, including small molecules\, antibodies\, oligonucleotides and new modalities. \n\n\n\nSome users and projects are at the intersection between chemical biology and drug discovery. This webinar aims to guide users to the call that best suits the needs of their project \n\n\n\nRegister here!\n\n\n\nOrganizer: the Chemical Biology Consortium Sweden and the Drug Discovery & Development platform
URL:https://www.scilifelab.se/event/calls-for-new-project-support-in-chemical-biology-and-drug-discovery-4/
LOCATION:Online event via Zoom
CATEGORIES:Event
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20260127T151500
DTEND;TZID=Europe/Stockholm:20260127T161500
DTSTAMP:20260407T112406
CREATED:20260120T162312Z
LAST-MODIFIED:20260120T162331Z
UID:10001728-1769526900-1769530500@www.scilifelab.se
SUMMARY:High-Speed AFM and Cryo-EM: Dynamics and Structures of Membrane Proteins
DESCRIPTION:Simon Scheuring\n\n\n\nWeill Cornell Medicine\, USA\n\n\n\nSimon Scheuring is Distinguished Professor of Anesthesiology Research in the Department of Anesthesiology at Weill Cornell Medicine in New York\, USA. \n\n\n\nHe is a trained biologist (Biozentrum\, University of Basel\, Switzerland). During his MSc and PhD\, he learned electron microscopy (EM) and atomic force microscopy (AFM) for the structure determination of membrane proteins such as aquaporins and sugar transporters. During his postdoc and as research assistant (Institut Curie\, Paris\, France)\, he learned membrane physical chemistry and developed AFM for the study of native membranes and ventured into setting up his lab as a junior research director at the Institut Curie. Promoted to senior research director\, he built a larger laboratory in Marseille (INSERM / Aix-Marseille Université\, France). In 2017\, he moved to Weill Cornell Medicine\, where he got appointed as Professor in the Department of Anesthesiology (WCM\, New York\, USA). Simon Scheuring’s laboratory develops and applies AFM-technologies for the study of membrane phenomena\, such as membrane protein structure\, assembly\, diffusion\, and conformational dynamics of unlabeled single molecules\, bridging structure and function. Over the past years\, his laboratory has been instrumental in the development of High-Speed AFM (HS-AFM) methods\, extracting quasi-atomic structural details from single molecule AFM data\, and reaching millisecond temporal resolution for the analysis of conformational dynamics. In recent works\, his laboratory combines HS-AFM with cryo-EM to acquire an integrated understanding of the dynamics and structures of membrane proteins. \n\n\n\nAbstract\n\n\n\nHigh-speed atomic force microscopy (HS-AFM) is a powerful technique that provides dynamic movies of biomolecules at work. First\, I will briefly review our recent developments to break temporal limitations to characterize molecular dynamics by developing HS-AFM line scanning (HS-AFM-LS) and HS-AFM height spectroscopy (HS-AFM-HS) [1]\, and resolution limitations by developing Localization AFM (LAFM) [2]. Then\, I will detail how we used HS-AFM to analyze membrane-embedded TRPV3 at the single-molecule level\, and discovered a previously unobserved\, transient\, and reversible pentameric state of TRPV3\, while cryo-EM analysis allowed to resolve the first structure of a pentameric TRP channel [3\,4]. Finally\, I will report about our most recent efforts to develop and apply 3D-AFM for the characterization of the water structure on protein surfaces [5]. \n\n\n\nReferences: \n\n\n\n[1] Heath et al.\, Nature Communications\, 2018\, 9(1):4983\, High-Speed AFM Height Spectroscopy (HS-AFM-HS): Microsecond dynamics of unlabeled biomolecules. \n\n\n\n[2] Heath et al.\, Nature\, 2021\, 594(7863):385–390\, doi:10.1038/s41586-021-03551-x\, Localization Atomic Force Microscopy. \n\n\n\n[3] Lansky et al.\, Nature\, 2023\, 621(7977)\, 206–214\, doi:10.1038/s41586-023-06470-1\, A pentameric TRPV3 channel with a dilated pore. \n\n\n\n[4] Lansky et al. Nature Communications\, 2025\, 16(4520). https://doi.org/10.1038/s41467-025-59798-9\, Structural dynamics and permeability of the TRPV3 pentamer. [5] Ma et al.\, submitted\, 2025\, Aquaporins destructure water above the pore. \n\n\n\nHost: Stavros Azinas stavros.azinas@scilifelab.se
URL:https://www.scilifelab.se/event/high-speed-afm-and-cryo-em-dynamics-and-structures-of-membrane-proteins/
LOCATION:Air&Fire\, SciLifeLab Stockholm\, Tomtebodavägen 23A\, Solna\, Sweden
CATEGORIES:Event
ATTACH;FMTTYPE=image/jpeg:https://www.scilifelab.se/wp-content/uploads/2023/10/Campus-solna-seminar-picture.jpg
ORGANIZER;CN="Spotlight Seminar Series":MAILTO:events@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20260127T140000
DTEND;TZID=Europe/Stockholm:20260127T150000
DTSTAMP:20260407T112406
CREATED:20260119T123255Z
LAST-MODIFIED:20260123T100047Z
UID:10001725-1769522400-1769526000@www.scilifelab.se
SUMMARY:How to Terminate Transcription at the Right Place
DESCRIPTION:Gene‑Wei Li\, Associate Professor Massachusetts Institute of Technology (MIT)\, USA \n\n\n\n\n\n\n\nAbstract\n\n\n\nPrecise transcription termination is essential for defining gene boundaries and achieving proper RNA output. I will discuss two recent advances regarding transcription termination in bacteria. First\, we re-defined the features required for intrinsic terminators: in addition to the canonical hairpin and U-tract\, two conserved sequence motifs are also necessary. This new definition quantitatively explains variations in termination efficiency and accurately pinpoints functional terminators genome-wide. Second\, we showed that many bacteria have evolved purine-rich genes to avoid premature transcription termination\, especially in species with “runaway transcription\,” i.e.\, those uncoupled transcription-translation. This bias imposes strong evolutionary constraints on codon usage and the assimilation of foreign genes. Together\, these principles illuminate the design principles of bacterial gene sequences and how genomes encode the correct endpoints of transcription. \n\n\n\nBiography\n\n\n\nGene‑Wei Li is an Associate Professor of Biology at Massachusetts Institute of Technology (MIT) and an Investigator at Howard Hughes Medical Institute (HHMI). He earned a B.S. in Physics from National Tsinghua University (2004) and a Ph.D. in Physics from Harvard University (2010)\, followed by a postdoctoral fellowship at University of California\, San Francisco (UCSF). His research focuses on how bacterial genomes encode quantitative control over protein production — exploring how cells optimize proteome composition through precise regulation of transcription\, translation\, and RNA processing. \n\n\n\n \n\n\n\nHost; Vicente Pelechano vicent.pelechano@scilifelab.se
URL:https://www.scilifelab.se/event/how-to-terminate-transcription-at-the-right-place/
LOCATION:Air&Fire\, SciLifeLab Stockholm\, Tomtebodavägen 23A\, Solna\, Sweden
CATEGORIES:Event
ATTACH;FMTTYPE=image/jpeg:https://www.scilifelab.se/wp-content/uploads/2023/10/Campus-solna-seminar-picture.jpg
ORGANIZER;CN="Spotlight Seminar Series":MAILTO:events@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20260127T080000
DTEND;TZID=Europe/Stockholm:20260128T150000
DTSTAMP:20260407T112406
CREATED:20250624T150224Z
LAST-MODIFIED:20250925T083137Z
UID:10001570-1769500800-1769612400@www.scilifelab.se
SUMMARY:Metabolomics in Life Science
DESCRIPTION:After the great success of the 2024 Metabolomics in Life Science conference\, the Organizing Committee is thrilled to announce the second edition in 2026!Date: 27-28 January\, 2026Venue: Vävenscenen\, Umeå \n\n\n\n\nUmeå University warmly invites you to Metabolomics in Life Science 2026\, showcasing the latest NMR- and MS-based metabolomics research from Sweden\, the Nordics\, and beyond. The conference brings together researchers from around the world to share knowledge and discuss advances in areas like clinical and precision medicine\, plant metabolomics\, spatial and single-cell metabolomics\, multi-omics\, and computational/AI applications. \n\n\n\nThe event is organized by SciLifeLab platforms in Umeå: Swedish NMR Centre (SNC)\, Swedish Metabolomics Centre (SMC)\, and Computational Analytics Support Platform (CASP). \n\n\n\nThe program includes six keynote speakers from leading institutions\, plus an industry exhibition showcasing the latest technologies and services in metabolomics research. \n\n\n\nRegistration is now open – Register here \n\n\n\nQuestions? Contact: \n\n\n\n\nIlona Dudka – ilona.dudka@umu.se\n\n\n\nKate Bennett – katie.bennett@umu.se\n\n\n\n\nLooking forward to welcoming everyone in Umeå in January 2026! \n\n\n\nRead more\n\n\n\nOrganizersSwedish Metabolomics Centre (SMC)  \n\n\n\nNMR Core facility \n\n\n\nComputational Analytics Support Platform (CASP)
URL:https://www.scilifelab.se/event/metabolomics-in-life-science/
LOCATION:Väven\, Storgatan 46A\, Umeå\, 90326\, Sweden
CATEGORIES:Event
ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2025/06/Umea.png
ORGANIZER;CN="Swedish Metabolomics Centre (SMC)":MAILTO:annika.johansson01@umu.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20260126T151500
DTEND;TZID=Europe/Stockholm:20260126T161500
DTSTAMP:20260407T112406
CREATED:20251211T124150Z
LAST-MODIFIED:20251211T124151Z
UID:10001681-1769440500-1769444100@www.scilifelab.se
SUMMARY:[The Svedberg seminar] - How to Terminate Transcription at the Right Place
DESCRIPTION:Gene‑Wei Li \n\n\n\nAssociate Professor Massachusetts Institute of Technology (MIT)\, USA \n\n\n\nBio\n\n\n\nGene‑Wei Li is an Associate Professor of Biology at Massachusetts Institute of Technology (MIT) and an Investigator at Howard Hughes Medical Institute (HHMI). He earned a B.S. in Physics from National Tsinghua University (2004) and a Ph.D. in Physics from Harvard University (2010)\, followed by a postdoctoral fellowship at University of California\, San Francisco (UCSF). His research focuses on how bacterial genomes encode quantitative control over protein production — exploring how cells optimize proteome composition through precise regulation of transcription\, translation\, and RNA processing. \n\n\n\nHow to Terminate Transcription at the Right Place \n\n\n\nPrecise transcription termination is essential for defining gene boundaries and achieving proper RNA output. I will discuss two recent advances regarding transcription termination in bacteria. First\, we re-defined the features required for intrinsic terminators: in addition to the canonical hairpin and U-tract\, two conserved sequence motifs are also necessary. This new definition quantitatively explains variations in termination efficiency and accurately pinpoints functional terminators genome-wide. Second\, we showed that many bacteria have evolved purine-rich genes to avoid premature transcription termination\, especially in species with “runaway transcription\,” i.e.\, those uncoupled transcription-translation. This bias imposes strong evolutionary constraints on codon usage and the assimilation of foreign genes. Together\, these principles illuminate the design principles of bacterial gene sequences and how genomes encode the correct endpoints of transcription \n\n\n\n \n\n\n\nHost: Johan Elf johan.elf@icm.uu.se UU
URL:https://www.scilifelab.se/event/the-svedberg-seminar-gene-wei-li/
LOCATION:BMC Room C8:301\, Husargatan 3\, Uppsala\, Sweden
CATEGORIES:Event
ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2022/02/Picture1-The-Svedberg.png
ORGANIZER;CN="The Svedberg Seminar Series":MAILTO:thesvedberg@scilifelab.uu.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20260123T100000
DTEND;TZID=Europe/Stockholm:20260123T110000
DTSTAMP:20260407T112406
CREATED:20251219T093846Z
LAST-MODIFIED:20251219T113322Z
UID:10001686-1769162400-1769166000@www.scilifelab.se
SUMMARY:Genetic code reprogramming for the discovery of macrocycles for therapeutic innovation
DESCRIPTION:Hiroaki Suga\, Ph.D.Professor\, Department of Chemistry\, School of Science\, The University of Tokyo \n\n\n\nHiroaki Suga is best known for his work on artificial ribozymes (Flexizyme) and their application in mRNA display (RaPID\, random nonstandard peptide integrated discovery). He is also the founder of the very successful drug discovery company PeptiDream\, Inc. He was awarded the Wolf Prize in Chemistry in 2023. \n\n\n\nHost: David Drew\, SciLifeLab
URL:https://www.scilifelab.se/event/genetic-code-reprogramming-for-the-discovery-of-macrocycles-for-therapeutic-innovation/
LOCATION:Air&Fire\, SciLifeLab Stockholm\, Tomtebodavägen 23A\, Solna\, Sweden
CATEGORIES:Event
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20260123T090000
DTEND;TZID=Europe/Stockholm:20260123T170000
DTSTAMP:20260407T112406
CREATED:20251204T133007Z
LAST-MODIFIED:20260119T080732Z
UID:10001679-1769158800-1769187600@www.scilifelab.se
SUMMARY:Unlocking Precision Health: From Molecular Insights to Clinical Impact in Complex Diseases
DESCRIPTION:The 3rd Symposium on Complex Diseases \n\n\n\nJoin us for an exciting day dedicated to advancing precision health and tackling the challenges of complex diseases. This symposium brings together leading researchers\, clinicians\, and industry to explore how molecular insights can transform clinical practice and improve patient outcomes. \n\n\n\nFor information about the symposium in Swedish: Unlocking Precision Health: From Molecular Insights to Clinical Impact in Complex Diseases (Swe). \n\n\n\nConfirmed Speakers:\n\n\n\n\nOskar Frisell\, Karolinska Institutet\n\n\n\nAndrea Ganna\, University of Helsinki\, Finland\n\n\n\nLina Jonsson\, University of Gothenburg\n\n\n\nRichard Landberg\, Chalmers University of Technology\n\n\n\nTuuli Lapalainen\, KTH Royal Institute of Technology\n\n\n\nRuth Loos\, University of Copenhagen\, Denmark\n\n\n\nOlle Melander\, Lund University\n\n\n\nRichard Rosenquist Brandell\, Karolinska Institutet\n\n\n\nPeter Würtz\, Nightingale Health\, Finland\n\n\n\n\nRegistration\n\n\n\nRegister via this form: https://forms.gle/6C7QzrzxwJ9NBPjd8. Registration deadline: 15 January 2026 \n\n\n\nAbstract Submission deadline: 5 January 2026 \n\n\n\nProgram\n\n\n\nProgram symposium complex diseases Jan 23 2026_FINALDownload\n\n\n\nWhy attend?\n\n\n\nExpand your expertise in genomics\, multi-omics\, and precision medicine. \n\n\n\nNetwork with experts and peers across academia\, healthcare\, and industry. \n\n\n\nParticipate in rapid talks\, poster sessions\, and lively discussions.
URL:https://www.scilifelab.se/event/unlocking-precision-health-from-molecular-insights-to-clinical-impact-in-complex-diseases/
LOCATION:Operaterassen\, Karl XII:s Torg\, Stockholm\, Sweden
CATEGORIES:Event
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20260120T151500
DTEND;TZID=Europe/Stockholm:20260120T161500
DTSTAMP:20260407T112406
CREATED:20260108T130106Z
LAST-MODIFIED:20260113T112254Z
UID:10001693-1768922100-1768925700@www.scilifelab.se
SUMMARY:Mapping cells at scale: from tissue volumes to community challenges in vEM
DESCRIPTION:Speaker: Aubrey WeigelProject Scientist\, CellMap Project TeamHoward Hughes Medical Institute\, Janelia Research Campus \n\n\n\nAbstract\n\n\n\n\n\n\n\nLarge-scale\, high-resolution imaging of subcellular architecture using volume electron microscopy (vEM) unlocks new opportunities for biological discovery – but realizing this potential requires more than just data acquisition. Scalable infrastructure\, robust protocols\, and trained personnel are critical to extract consistent insight from these complex datasets and make them useful to the broader community. The CellMap Project Team represents a coordinated effort to scale vEM-based segmentation across six dimensions: dataset scale\, biological diversity\, organelle classification complexity\, team training\, analytical depth\, and open access.  \n\n\n\nThrough modular training programs\, systematic quality control\, and block-wise processing tools\, the project has grown from individual cell volumes to tissue-scale annotation across dozens of organisms and sample types. Annotated datasets are openly shared through OpenOrganelle\, providing the community with immediate access to high-resolution volumes and voxel-level segmentations. To further catalyze progress in automated segmentation\, we launched the CellMap Segmentation Challenge – a large-scale\, open competition featuring expertly annotated training data from over 20 eFIB-SEM datasets and more than 40 unique organelle classes.  \n\n\n\nWe describe how workflows and infrastructure evolved to support this scaling effort\, with a focus on designing datasets that are tailored for specific biological insight yet structured for broad reuse. By scaling people\, protocols\, and pipelines in parallel – and committing to open data practices – the CellMap Project Team provides a model for reproducible\, high-resolution cellular mapping at scale. \n\n\n\nregistration\n\n\n\nBiography \n\n\n\nAubrey Weigel is currently a Project Scientist of the CellMap Project Team at HHMI – Janelia Research Campus. The team uses advanced imaging technologies to study the ultrastructure of subcellular organelles under both healthy and pathological conditions. Aubrey’s previous research background is in biophysics\, with an emphasis in microscopy. Her formal training is in physics and engineering.  \n\n\n\nDuring her graduate work Aubrey was the co-discoverer of ergodicity breaking in cells along with Diego Krapf\, driving a pivotal shift in the field of diffusion analysis in living systems. Throughout her postdoctoral career under the guidance of Jennifer Lippincott-Schwartz\, she applied her training in physics and microscopy directly to answer biological questions. Here\, Aubrey unraveled the underlying structure of the endoplasmic reticulum and revealed its complex dynamics. She also uncovered the nano-anatomy of early secretory compartments and discovered a new\, dynamic organelle\, responsible for delivering newly synthesized cargo from the endoplasmic reticulum to the Golgi.  \n\n\n\nAubrey’s recent work as the leader of the Cell Organelle Segmentation in Electron Microscopy (COSEM) project includes developing an invaluable tool for cell biology – an analysis pipeline based on deep learning architectures for segmentation – allowing comprehensive reconstruction and analysis of organelles within entire cells imaged by volumetric electron microscopy. CellMap is now building upon this pipeline to generate\, characterize\, and discover how cells look in their native tissue environments – acting as a hub of collaborations that brings together scientists of different disciplines. Aubrey is committed to integrating her multi-disciplinary training into facilitating large-effort\, collaborative\, team projects to take on challenging scientific problems and sharing these resources with the broader scientific community.
URL:https://www.scilifelab.se/event/mapping-cells-at-scale-from-tissue-volumes-to-community-challenges-in-vem/
LOCATION:Air&Fire\, SciLifeLab Stockholm\, Tomtebodavägen 23A\, Solna\, Sweden
CATEGORIES:Event
ATTACH;FMTTYPE=image/jpeg:https://www.scilifelab.se/wp-content/uploads/2023/10/Campus-solna-seminar-picture.jpg
ORGANIZER;CN="Spotlight Seminar Series":MAILTO:events@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20251218T000000
DTEND;TZID=Europe/Stockholm:20251218T235900
DTSTAMP:20260407T112406
CREATED:20251202T123921Z
LAST-MODIFIED:20251202T124514Z
UID:10001677-1766016000-1766102340@www.scilifelab.se
SUMMARY:SciLifeLab PULSE - information webinar for applicants
DESCRIPTION:This webinar (two time options available) gives PULSE applicants an opportunity to receive information on e.g. the matchmaking and application process\, as well as eligibility rules. There will also be time for Q&A:s. Find out more about the SciLifeLab PULSE postdoc program here The 2nd SciLifeLab PULSE Call opened on December 15! \n\n\n\n\n\n\n\n\n\n\n\nWebinar registration\n\n\n\n\n\nWebinar on December 18\, 2025\, at 09:00 am\, UTC+1 \n\n\n\n\n\nRegister here\n\n\n\n\n\n\n\nWebinar on December 18\, 2025\, at 16:00 pm\, UTC+1 \n\n\n\n\n\nRegister here
URL:https://www.scilifelab.se/event/scilifelab-pulse-information-webinar-for-applicants/
LOCATION:Online event via Zoom
CATEGORIES:Event
ATTACH;FMTTYPE=image/jpeg:https://www.scilifelab.se/wp-content/uploads/2024/12/AdobeStock_519582269-scaled-1.jpeg
ORGANIZER;CN="SciLifeLab Event":MAILTO:events@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20251216T151500
DTEND;TZID=Europe/Stockholm:20251216T161500
DTSTAMP:20260407T112406
CREATED:20251215T084843Z
LAST-MODIFIED:20251215T084907Z
UID:10001682-1765898100-1765901700@www.scilifelab.se
SUMMARY:[Spotlight Seminar Series] The innate power of natural killer cells in cancer therapy
DESCRIPTION:Professor Karl-Johan Malmberg (M.D. Ph.D) \, Oslo University \n\n\n\nBiography\n\n\n\nProfessor Karl-Johan Malmbergis a Specialist in Hematology with over 25 years of experience in NK cell research and cancer immunotherapy. He is the Director of a Norwegian Research Council Center of Excellence\, The Precision Immunotherapy Alliance (PRIMA) and leads an international team of 20 scientists based in laboratories both at the University of Oslo\, Norway and the Karolinska Institutet\, Sweden. He is also the Scientific Director of the Center for Advanced Cell and Gene Therapy (ACT) at Oslo University Hospital. The group focus on deciphering basic cellular and molecular mechanisms regulating NK cell function and seek to translate insights from these efforts in the design of novel approaches for NK-cell based cancer immunotherapy against cancer. \n\n\n\nRelevant Publications\n\n\n\nThe innate power of natural killer cells in cancer therapy. \n\n\n\nSohlberg E\, Malmberg KJ.Nat Med. 2025 Jun;31(6):1755-1756. doi: 10.1038/s41591-025-03712-9.PMID: 40355615 \n\n\n\nPan-cancer profiling of tumor-infiltrating natural killer cells through transcriptional reference mapping. \n\n\n\nNetskar H\, Pfefferle A\, Goodridge JP\, Sohlberg E\, Dufva O\, Teichmann SA\, Brownlie D\, Michaëlsson J\, Marquardt N\, Clancy T\, Horowitz A\, Malmberg KJ.Nat Immunol. 2024 Aug;25(8):1445-1459. doi: 10.1038/s41590-024-01884-z. Epub 2024 Jul 2.PMID: 38956379 \n\n\n\n \n\n\n\nHost: Adnane Achour adnane.achour@ki.se
URL:https://www.scilifelab.se/event/spotlight-seminar-series-the-innate-power-of-natural-killer-cells-in-cancer-therapy/
LOCATION:Air&Fire\, SciLifeLab Stockholm\, Tomtebodavägen 23A\, Solna\, Sweden
CATEGORIES:Event
ATTACH;FMTTYPE=image/jpeg:https://www.scilifelab.se/wp-content/uploads/2023/10/Campus-solna-seminar-picture.jpg
ORGANIZER;CN="SciLifeLab Event":MAILTO:events@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20251215T151500
DTEND;TZID=Europe/Stockholm:20251215T161500
DTSTAMP:20260407T112406
CREATED:20251120T123638Z
LAST-MODIFIED:20251125T132656Z
UID:10001670-1765811700-1765815300@www.scilifelab.se
SUMMARY:[The Svedberg seminar] - Optogenetic control of gene expression dynamics in single cells
DESCRIPTION:Mary Dunlop \n\n\n\nProfessor Boston University\, USA \n\n\n\nBio\n\n\n\nMary Dunlop is a Professor of Biomedical Engineering and Dorf-Ebner Distinguished Faculty Fellow at Boston University. She holds additional affiliations in Bioinformatics and Molecular Biology\, Cell Biology & Biochemistry. She graduated from Princeton University with a B.S.E. in Mechanical and Aerospace Engineering and a minor in Computer Science. She then received her M.S. and Ph.D. in Mechanical Engineering from the California Institute of Technology. In recognition of her outstanding research contributions\, she has received many honors including election as an AIMBE Fellow\, the NSF Transitions Award\, ACS Synthetic Biology Young Investigator Award\, DOE Early Career Award\, and NSF CAREER Award. She is also the recipient of several mentoring and teaching awards\, including Boston University’s Award for Excellence in Mentoring Postdocs and the College of Engineering Teaching Excellence Award. \n\n\n\nOptogenetic control of gene expression dynamics in single cells \n\n\n\nEmerging approaches that integrate optogenetics with feedback control are transforming our ability to precisely manipulate microbial gene expression dynamics. In this talk\, I will present how we harnessed deep neural networks and model predictive control to impose real-time\, cell-specific gene expression patterns in bacteria\, revealing crucial links between dynamic regulation and functional outcomes such as antibiotic resistance. I will also highlight our use of optogenetic tools and information theory to understand how variable expression of a key transcription factor influences downstream stress response genes and impacts bacterial survival under antimicrobial stress. These approaches provide new insights into the significant roles of cellular heterogeneity and dynamic regulation\, advancing our understanding of gene expression and microbial behavior at the single-cell level. \n\n\n\n \n\n\n\nHost: Daniel Jones daniel.jones@icm.uu.se\, UU
URL:https://www.scilifelab.se/event/the-svedberg-seminar-mary-dunlop/
LOCATION:BMC Room C8:301\, Husargatan 3\, Uppsala\, Sweden
CATEGORIES:Event
ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2022/02/Picture1-The-Svedberg.png
ORGANIZER;CN="The Svedberg Seminar Series":MAILTO:thesvedberg@scilifelab.uu.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20251211T130000
DTEND;TZID=Europe/Stockholm:20251211T160000
DTSTAMP:20260407T112406
CREATED:20251027T112529Z
LAST-MODIFIED:20251211T084725Z
UID:10001654-1765458000-1765468800@www.scilifelab.se
SUMMARY:Science & SciLifeLab Prize Scientific Symposium 2025
DESCRIPTION:Welcome to the Scientific Symposium where the winners of the 2025 Science & SciLifeLab Prize for Young Scientists will present their research! \n\n\n\nScience\, the American Association for the Advancement of Science (AAAS)\, and SciLifeLab joined forces in 2013\, creating the Science & SciLifeLab Prize for Young Scientists to recognize excellence amongst young researchers from around the world. A global Prize aimed at rewarding scientists at an early stage of their careers. \n\n\n\nThe Prize is awarded in four different categories and the winners will be announced on November 14th \n\n\n\n\nUche Medoh\, Grand Prize Winner in Molecular Medicine\n\n\n\nLiam Lachs\, Category Winner in Ecology and Environment\n\n\n\nNitzan Tal\, Category Winner in Genomics\, Proteomics\, and Systems Biology Approaches\n\n\n\nKing L. Hung\, Category Winner in Cell and Molecular Biology\n\n\n\n\nAll four winners of the Science & SciLifeLab Prize for Young Scientists are invited to Sweden December 8-13 to participate in a unique week filled with events in honor of science. They will have the opportunity to meet with leading scientists in their field of research and create life-long connections to support their careers. \n\n\n\n \n\n\n\nThe symposium will take place at beautiful Grand Hôtel in Stockholm. \n\n\n\nSeats are limited so register today for your chance to meet with the winners and the the AAAS/Science editor team AND our honorary guest\, the Grand Prize Winner from 2024\, Andrija Sente. \n\n\n\nRegistration\n\n\n\nProgram\n\n\n\nScience SciLifeLab Prize SymposiumDownload\n\n\n\nRead more about the Prize\n\n\n\nRead more about the winners
URL:https://www.scilifelab.se/event/science-scilifelab-prize-scientific-symposium-2025/
LOCATION:Auditorium Stockholm\, Grand Hôtel\, Södra Blasieholmshamnen 8\, Stockholm\, 10327\, Sweden
CATEGORIES:Event
ATTACH;FMTTYPE=image/jpeg:https://www.scilifelab.se/wp-content/uploads/2020/05/prize_2018_puff.jpg
ORGANIZER;CN="SciLifeLab Event":MAILTO:events@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20251210T100000
DTEND;TZID=Europe/Stockholm:20251210T120000
DTSTAMP:20260407T112406
CREATED:20251031T080951Z
LAST-MODIFIED:20251120T111741Z
UID:10001657-1765360800-1765368000@www.scilifelab.se
SUMMARY:Teaching and training as "communication": leveraging cognitive and communication theories to strengthen learning
DESCRIPTION:Invited speaker: Professor Rochelle E. Tractenberg\, Georgetown University \n\n\n\nSciLifeLab as a Research Infrastructure incorporates people across a variety of technically complex fields. Staff-scientists and researchers often need to communicate about their complex work to people who are not fully familiar with all the details. Swedish universities offer training or support for scientists to help them communicate complex ideas for the public. However\, we don’t often consider that these communication theories and strategies might be equally useful for promoting or strengthening a learning culture across the organization or that such communication strategies are useful in the training and teaching staff-scientists and researchers are involved in. This talk by Professor Tractenberg from Georgetown University will outline two theories – one for communication and one for change management – which have been augmented with cognitive theories so that they can optimize teaching and training and with this strengthen learning. \n\n\n\n\n\n\n\n\n\n \n\n\n\nWelcome to a seminar where Professor Rochelle Tractenberg will present her recent work combining communication with change management strategies. We will learn how we can more efficiently can promote change around complex information – such as encouraging researchers to utilize a new method or tool\, or instructing students about a complex aspect of the field they’re studying. \n\n\n\nFor registrants wishing to participate online\, please indicate this in the registration form. For people attending onsite there will be a light lunch provided after the seminar. \n\n\n\nRegister here\n\n\n\nScientific abstract\n\n\n\nTractenberg’s augmented Diffusion of Innovation (aDOI\, Tractenberg\, 2023) is a theoretical framework for understanding and leveraging the cognitive complexity of messages so as to optimize uptake of the new information by any hearer. aDOI is adapted\, through cognitive theory\, from Rogers’ DOI communication model (1965/2003). A concrete\, stepwise theory of change management (ToCM\, Kotter 2012) originated in business\, and has been widely used across business and leadership programs. This theory has also been augmented with cognitive theory (aToCM\, Tractenberg 2024). Together\, these two revised models provide a strategy for promoting change around complex information – such as encouraging scientists to utilize a new method or tool\, or educating students about a complex aspect of the field they’re studying. Tractenberg’s augmented Diffusion of Innovation and Theory of Change Management make encouraging uptake of new ideas\, or new knowledge\, more consistent with human reasoning. These can support instructors’ adaptation of existing courses to include new information/technology or techniques\, and can also help instructors to learn new evidence-based methods of teaching and assessing.
URL:https://www.scilifelab.se/event/teaching-and-training-as-communication-leveraging-cognitive-and-communication-theories-to-strengthen-learning/
LOCATION:Air&Fire\, SciLifeLab Stockholm\, Tomtebodavägen 23A\, Solna\, Sweden
CATEGORIES:Event
ORGANIZER;CN="Training Hub":MAILTO:traininghub@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20251208T151500
DTEND;TZID=Europe/Stockholm:20251208T161500
DTSTAMP:20260407T112406
CREATED:20251120T122932Z
LAST-MODIFIED:20251124T132739Z
UID:10001669-1765206900-1765210500@www.scilifelab.se
SUMMARY:[The Svedberg seminar] - The origins of locally adaptive loci
DESCRIPTION:Gabriela Montejo-Kovacevich \n\n\n\nAssistant Professor SciLifeLab Fellow Uppsala University \n\n\n\n\n\n\n\nBio\n\n\n\nGabriela Montejo-Kovacevich is a SciLifeLab fellow and Assistant Professor that recently established her lab at the Animal Ecology program in the Department of Ecology and Genetics at EBC (Uppsala University). Her group studies mechanisms that promote or constrain local adaptation. By integrating genomics with ecological and natural history approaches\, mainly in insects\, they explore the mode and tempo of evolution in natural populations. \n\n\n\nThe origins of locally adaptive lociHow do organisms evolve to inhabit diverse environments? This seminar explores the mode and tempo of evolution in the wild by studying local adaptation in three insect systems. I will first present work on Heliconius butterflies along a 1500m altitudinal gradient in the Andes\, revealing strong\, repeated selection at high-altitude\, with evidence for adaptive introgression from pre-adapted species. I will then turn to a ‘megapest’ moth (Helicoverpa) that is threatening food security in Brazil through bidirectional adaptive introgression conferring insecticide resistance. Finally\, I will introduce Euphydryas editha\, a Californian butterfly capable of rapid\, heritable shifts in host plant use offering a rare glimpse into ongoing behavioural adaptation to anthropogenic change. Together\, these systems demonstrate how evolutionary forces interact to shape resilience in a rapidly changing world. \n\n\n\nHost: Göran Arnqvist Goran.Arnqvist@ebc.uu.se\, UU
URL:https://www.scilifelab.se/event/the-svedberg-seminar-gabriela-montejo-kovacevich/
LOCATION:BMC Room C8:301\, Husargatan 3\, Uppsala\, Sweden
CATEGORIES:Event
ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2022/02/Picture1-The-Svedberg.png
ORGANIZER;CN="The Svedberg Seminar Series":MAILTO:thesvedberg@scilifelab.uu.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20251205T101500
DTEND;TZID=Europe/Stockholm:20251205T110000
DTSTAMP:20260407T112406
CREATED:20251120T134320Z
LAST-MODIFIED:20251120T140035Z
UID:10001671-1764929700-1764932400@www.scilifelab.se
SUMMARY:Discovery and developmentof GRK2-biased beta 2-adrenergic receptor agonists for the treatment of metabolic disorders
DESCRIPTION:Presenter: Dr Benjamin Pelcman\, Atrogi AB \n\n\n\nAtrogi AB is biotech company pioneering first-in-class treatments to revolutionize metabolic health. The talk will describe how targeting a novel GRK-biased b2-adrenergic receptor signaling pathway allows for the successful design of compounds useful in the treatment of disorders like type 2 diabetes (T2D)\, obesity and muscular wasting. The approach will be exemplified by the invention\, selection and development of ATR-258\, a b2-AR agonist that was developed for T2D and is about to enter phase 2 clinical trials. During the exploration of the chemical space\, a diverse set of molecules were synthesized\, and their effect on the downstream signaling will be discussed. In addition\, the seminar will illustrate differences between drug development in Big Pharma and small biotech and the challenges of working in an environment with limited resources. \n\n\n\nAfter receiving his Ph.D. in Organic Chemistry at KTH and a post doc session at Dartmouth College\, NH\, USA\, Benjamin joined Astra Pain Control\, first in Södertälje and then in Montreal\, as a medicinal chemist. Benjamin has also held various positions at Pharmacia & Upjohn\, Karo Bio\, Biolipox and Orexo. After having started his own consultancy company\, BeePCo\, he came in contact with Atrogi where he was employed first as a CEO and later as Head of Chemistry and IP. Benjamin is now retired but is still working as a consultant for Atrogi and other small biotechs.
URL:https://www.scilifelab.se/event/discovery-and-developmentof-grk2-biased-beta-2-adrenergic-receptor-agonists-for-the-treatment-of-metabolic-disorders/
LOCATION:BMC Room C4:301\, Husargatan 3\, entrance C1\, Uppsala\, Sweden
CATEGORIES:Event
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20251204T090000
DTEND;TZID=Europe/Stockholm:20251204T170000
DTSTAMP:20260407T112406
CREATED:20251006T130957Z
LAST-MODIFIED:20251007T070354Z
UID:10001632-1764838800-1764867600@www.scilifelab.se
SUMMARY:3D Imaging in Health and Disease
DESCRIPTION:Characterizing molecular and cellular complexities in 3D is an emerging field allowing to study biology in its true context. \n\n\n\nIn this symposium national and international experts will present developments and applications in 3D imaging aimed to improve health and disease analysis across scales \n\n\n\nPlease register by sending an e-mail to hans.blom@scilifelb.se \n\n\n\n \n\n\n\nProgram 3D symposiumDownload
URL:https://www.scilifelab.se/event/3d-imaging-in-health-and-disease/
LOCATION:Nobel Forum\, Nobels väg 1\, Solna\, Sweden
CATEGORIES:Event
ORGANIZER;CN="integrated Microscopy Technologies":MAILTO:hblom@kth.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20251204T090000
DTEND;TZID=Europe/Stockholm:20251204T103000
DTSTAMP:20260407T112406
CREATED:20250812T104118Z
LAST-MODIFIED:20250929T063104Z
UID:10001579-1764838800-1764844200@www.scilifelab.se
SUMMARY:User meeting for your multi-modal research projects
DESCRIPTION:Boost your research — Book a private SciLifeLab planning and feedback session for your multi-modal research projects! \n\n\n\n \n\n\n\nRegister here\n\n\n\nOnce we have received your registration\, you will be sent the link to the online meeting. \n\n\n\nDate: December 4\, 9.00 – 10.30 Registration deadline: November 28 \n\n\n\nMultimodal molecular profiling and novel computational methods are transforming life science research\, but also pose new challenges in study design\, project resource planning and data management. SciLifeLab is a national resource of unique technologies and expertise available to life scientists\, in areas such as biomedicine\, ecology and evolution\, aiming to bring scientists together across traditional boundaries and foster collaborations with industry\, health care\, public research organizations and international partners. \n\n\n\nThe first Thursday of every month at 9.00 (except July and August)\, SciLifeLab offers an opportunity to jointly meet with representatives across the SciLifeLab service platforms\, to get feedback and help to plan\, design\, and refine new or ongoing multimodal research projects. Your project plans are discussed privately and remain confidential\, and information will not be shared outside of the service platforms. Note that for most studies\, follow-up meetings will be needed\, but our aim for these meetings is to provide an easy-access entry point for an overarching planning of multimodal studies. \n\n\n\nFor studies focusing on a single technology only\, please primarily contact our service platforms directly as described at the SciLifeLab homepage. \n\n\n\nTo make the best out of the allotted time\, we ask you to provide some background information about your project\, to help us ensure that the relevant experts are available to discuss your study.
URL:https://www.scilifelab.se/event/user-meeting-for-your-multi-modal-research-projects-3/
LOCATION:virtual event
CATEGORIES:Event
ATTACH;FMTTYPE=image/jpeg:https://www.scilifelab.se/wp-content/uploads/2025/08/AdobeStock_1081766437-scaled.jpeg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20251202T130000
DTEND;TZID=Europe/Stockholm:20251202T140000
DTSTAMP:20260407T112406
CREATED:20251103T123419Z
LAST-MODIFIED:20251103T125156Z
UID:10001658-1764680400-1764684000@www.scilifelab.se
SUMMARY:Is high-throughput electrophysiology possible?
DESCRIPTION:Register here\n\n\n\n\nOn site seminar – Electrophysiology Infrastructure\n\n\n\nLocation: Jörgen Lehmann\, Academicum\, Medicinaregatan 3 and SciLifeLab Gothenburg \n\n\n\n\nPresenters\n\n\n\n\nFredrik Elinder\, Professor\, Site director SciLifeLab Linköping\, Chemical Biology Consortium Sweden (CBCS)\, and Department of Biomedical and Clinical Sciences (BKV)\, Linköping University \n\n\n\n\n\nNina Ottosson\, Research Coordinator\, Chemical Biology Consortium Sweden (CBCS)\, and Department of Biomedical and Clinical Sciences (BKV)\, Linköping University \n\n\n\n\n\nThe electrophysiology unit at Linköping University\, part of Chemical Biology Consortium Sweden (CBCS) at SciLifeLab\, visits site Gothenburg\, and presents the infrastructure during a seminar. \n\n\n\nDuring the day\, 1-on-1 meetings with the presenters will be possible at The SciLifeLab office\, Medicinaregatan 3. Take the chance to discuss how your research questions can be answered through analyses of ion channels. Request is added in the registration form. \n\n\n\nThe electrophysiology unit\, a recent addition to SciLifeLab’s range of infrastructures\, is equipped with automated patch-clamp instrumentation\, and supports a wide range of electrophysiological studies involving both voltage-gated and ligand-gated ion channels\, including pharmacological screening\, cardiac safety assessments\, and biophysical investigations. \n\n\n\nWELCOME! \n\n\n\nFredrik Elinder and Nina Ottosson\, Electrophysiologists \n\n\n\nJosefine Sandström and Maria Smedh\, SciLifeLab site coordinators Webpage of the CBCS Linköping node. 
URL:https://www.scilifelab.se/event/is-high-throughput-electrophysiology-possible-2/
CATEGORIES:Event
ATTACH;FMTTYPE=image/jpeg:https://www.scilifelab.se/wp-content/uploads/2025/06/electrophysiology-visit.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20251202T100000
DTEND;TZID=Europe/Stockholm:20251202T113000
DTSTAMP:20260407T112406
CREATED:20251028T115513Z
LAST-MODIFIED:20251117T092940Z
UID:10001655-1764669600-1764675000@www.scilifelab.se
SUMMARY:Introduction to the Module System on Berzelius
DESCRIPTION:This training offers a practical introduction to the module system on Berzelius. The session will cover: \n\n\n\n\nhow to find modules on Berzelius\n\n\n\nload/unload modules\n\n\n\nuse modules in interactive or batch modes\n\n\n\ncreate your own module\n\n\n\n\nParticipants will also gain hands-on experience with these commands. By the end of the session\, you will be able to navigate the modules system Berzelius confidently and use them effectively for your research.-on experience with these commands. By the end of the session\, you will be able to navigate Berzelius confidently and use its resources effectively for your research. \n\n\n\nDate: December 2\, 2025Time: 10:00–11:30 \n\n\n\nTarget audience: The online event is open for all current and prospective Berzelius users. Please read the eligibility requirements for accessing Berzelius.Place: Online via Zoom (link provided upon registration) \n\n\n\nregistration\n\n\n\nPreliminary Agenda \n\n\n\nTimeSession TitleSpeaker(s)10:00–11:00Introduction to the Module System on BerzeliusSoumi Chaki11:00–11:30Open Q&A SessionBerzelius Application Expert\n\n\n\nThis event is a collaboration between National Supercomputer Centre (NSC) at Linköping University and SciLifeLab Data Centre. \n\n\n\nFor questions please contact soumi.chaki@liu.se (Soumi Chaki)
URL:https://www.scilifelab.se/event/introduction-to-the-module-system-on-berzelius/
LOCATION:Zoom
CATEGORIES:Event
ATTACH;FMTTYPE=image/jpeg:https://www.scilifelab.se/wp-content/uploads/2025/10/NSC-Berzelius-LiU-2025-3451-Photographer-Magnus-Johansson.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20251201T151500
DTEND;TZID=Europe/Stockholm:20251201T161500
DTSTAMP:20260407T112406
CREATED:20251119T104324Z
LAST-MODIFIED:20251119T104326Z
UID:10001668-1764602100-1764605700@www.scilifelab.se
SUMMARY:[The Svedberg seminar] - Genome organisation and patterns of molecular evolution
DESCRIPTION:Jennifer James \n\n\n\nAssistant Professor DDLS Fellow \n\n\n\n \n\n\n\n\n\n\n\nBio\n\n\n\nDr. Jennifer James did her PhD in population genetics with Adam Eyre-Walker at the University of Sussex. After a postdoctoral position at the University of Cambridge she moved to the US\, where she worked as a postdoctoral researcher with Joanna Masel at the University of Arizona\, which introduced her to the world of proteomics. She next moved to Uppsala and worked as a postdoctoral research fellow with Martin Lascoux prior to becoming a DDLS fellow and starting her own new research group in Molecular Evolution. Her group conducts research on patterns of molecular evolution both at the genome and proteome level\, with a focus on understanding mutational robustness. \n\n\n\n \n\n\n\n \n\n\n\nGenome organisation and patterns of molecular evolution\n\n\n\n \n\n\n\nIn my group\, we try to understand patterns of phenotypic evolution at the proteome level\, and molecular evolution across the genome. Key to this question is understanding how the genome is structured and organised. For example\, how pleiotropic are the effects of genes on average\, and how complex are gene networks? To give one case\, if pleiotropy is universal\, such that all genes affect all traits\, we expect all new mutations to have the same effect on fitness. However\, the extent of pleiotropy in real biological systems remains debated. In this seminar I will discuss our \n\n\n\n \n\n\n\nHost: Siv Andersson siv.andersson@icm.uu.se\, UU
URL:https://www.scilifelab.se/event/the-svedberg-seminar-jennifer-james/
LOCATION:BMC Room C8:301\, Husargatan 3\, Uppsala\, Sweden
CATEGORIES:Event
ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2022/02/Picture1-The-Svedberg.png
ORGANIZER;CN="The Svedberg Seminar Series":MAILTO:thesvedberg@scilifelab.uu.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20251128T090000
DTEND;TZID=Europe/Stockholm:20251128T093000
DTSTAMP:20260407T112406
CREATED:20251117T152805Z
LAST-MODIFIED:20251127T042951Z
UID:10001666-1764320400-1764322200@www.scilifelab.se
SUMMARY:Multimodal explorative testing in the ON-OFF ibrutinib trial in CLL
DESCRIPTION:Multimodal explorative testing in the ON-OFF ibrutinib trial in CLLRichard Rosenquist Brandell\, Karolinska Institutet & Karolinska University Hospital \n\n\n\nChronic lymphocytic leukaemia (CLL) is the most common leukaemia in the Western World and displays substantial variability in clinical course\, ranging from indolent disease requiring no therapy to highly aggressive forms with short survival despite treatment. Although the past decade has seen major advances in drug development\, CLL remains incurable. Targeted therapies\, particularly Bruton’s tyrosine kinase inhibitors (BTKi)\, have become central to CLL management. However\, continuous long-term BTKi administration\, such as with ibrutinib\, is associated with considerable significant side-effects\, including cardiac arrhythmias. Furthermore\, despite its proven efficacy in both treatment-naïve and relapsed/refractory CLL\, resistance to ibrutinib continues to challenge durable disease control. To address these limitations\, we conducted a phase 1b/2 prospective\, single-arm\, multicenter study evaluating controlled treatment cessation as a strategy to preserve tolerability and maintain sensitivity to ibrutinib\, while also improving cost-effectiveness. The study protocol incorporated serial blood sampling prior to treatment initiation and throughout on/off treatment periods. Here\, we leverage this unique longitudinal sample collection to perform multimodal profiling\, including genomic and transcriptomic sequencing as well as proteomics\, to investigate mechanisms of drug response and resistance. We provide an update on the current status of the study and ongoing analyses. \n\n\n\nregistration\n\n\n\nBiography \n\n\n\n\n\n\n\nRichard Rosenquist Brandell is Professor of Clinical Genetics at the Department of Molecular Medicine and Surgery\, Karolinska Institutet\, and Senior Physician in Clinical Genetics at Karolinska University Hospital\, Sweden. Focusing on hematological malignancies and utilizing high-throughput sequencing and other innovative technologies\, his research team has identified novel prognostic and predictive biomarkers that have refined disease classification and significantly improved patient risk-stratification and clinical decision-making. Richard Rosenquist Brandell initiated and led the Clinical Genomics Unit within Science for Life Laboratory (SciLifeLab) in Uppsala (2013-2017) and was platform director for the Clinical Genomics platform (2016-2021) within SciLifeLab\, which includes seven Clinical Genomics units across Sweden. He is currently Director of Genomic Medicine Sweden (GMS)\, a national infrastructure for implementation of precision medicine. Rosenquist Brandell is a member of the Nobel Assembly at Karolinska Institutet.
URL:https://www.scilifelab.se/event/multimodal-explorative-testing-in-the-on-off-ibrutinib-trial-in-cll/
LOCATION:Online event via Zoom
CATEGORIES:Event
ORGANIZER;CN="Clinical Talks":MAILTO:precisionmedicine@scilifelab.se
END:VEVENT
END:VCALENDAR