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DTSTART;TZID=Europe/Stockholm:20220405T153000
DTEND;TZID=Europe/Stockholm:20220405T163000
DTSTAMP:20260408T004219
CREATED:20220321T101658Z
LAST-MODIFIED:20220321T101728Z
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SUMMARY:Sustainability in Science: My Green Lab
DESCRIPTION:Cristalle Ruiz\n\n\n\nMarket Development Representative\, My Green Lab  \n\n\n\nResearchers in all stages of their career are welcome to attend and could find the talk useful. Kindly feel free to extend the invitation to your home universities. \n\n\n\nMy Green Lab is an internationally recognised non-profit organisation run by scientists aimed at introducing sustainable laboratory practices across the globe. We can find out more about My Green Lab’s mission\, the highly successful ‘Ambassador programme’ and other resources available from Cristalle Ruiz\, Market Development Representative of My Green Lab. The talk is intended to provide valuable insight into sustainability in science and the steps that could be implemented in our labs. \n\n\n\nCristalle Ruiz is the Market Development Representative for My Green Lab\, the leading global nonprofit supporting laboratory sustainability. Her role is to bring awareness to the benefits of sustainable practices across laboratories and manufacturers of laboratory products through My Green Lab’s market-leading programs. In her previous position\, Cristalle advocated for implementing renewable energy in the United States. She holds a bachelor’s degree in Environmental Business and Economics from Rutgers University. She will discuss and provide resources to build a culture of sustainability in the science industry. \n\n\n\n  \n\n\n\n \n\n\n\n PhD & Postdoc council (phd-council@scilifelab.se)
URL:https://www.scilifelab.se/event/sustainability-in-science-my-green-lab/
LOCATION:Online event via Zoom
CATEGORIES:Event
ORGANIZER;CN="SciLifeLab Solna PhD & Postdoc Council":MAILTO:phd-council@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220408T090000
DTEND;TZID=Europe/Stockholm:20220408T093000
DTSTAMP:20260408T004219
CREATED:20220330T131410Z
LAST-MODIFIED:20220330T132843Z
UID:10000574-1649408400-1649410200@www.scilifelab.se
SUMMARY:[Clinical Talks]Seeing is believing\, unraveling the discovery of a centimeter-long macro-bacteria
DESCRIPTION:On April 8\, Dr. Jean-Marie Volland\, Scientist at Berkeley Lab and Laboratory for Research in Complex Systems (LRC Systems)\, and Shailesh Date\, CEO of LRC Systems (Adj. Assoc. Professor at UCSF)\,will talk about their recent discovery and characterization of the macro-bacteria Ca. Thiomargarita magnifica. The threadlike single-cell bacterium\, commonly found in the Caribbean Mangroves\, is visible to the naked eye\, and able to grow up to 2 centimeters in length. In a recent effort\, an international team studied the “magnificent” organism using fluorescence\, x-ray\, and electron microscopy\, and fully sequenced the genome.  \n\n\n\nThrough a unique strategy of polyploidy\, along with compartmentalization of genomic material and protein synthesis in membrane-bound organelle\, the organism has been able to grow orders of magnitude over the theoretical limits for bacterial cells. The traditional view\, which has almost become dogmatic\, is that prokaryotes (bacteria and single-cell microbes) have free-floating DNA\, whereas eukaryotes (yeast and multicellular organisms) package their DNA in a nucleus. This new model organism blurs that line and offers amazing potential insights into biological evolutionary strategies\, many of which are as yet unexplored. One can only wonder at the type and number of new clinical innovations that will emerge as we continue exploring the frontiers of biology and biological complexity. \n\n\n\nRegister to receive zoom link\n\n\n\n  \n\n\n\n\n\n\n\nJean-Marie Volland is a Scientist at Lawrence Berkeley National Laboratory (Berkeley Lab) and at Laboratory of Research in Complex Systems (LRC Systems) in Menlo Park California. He obtained his PhD at the Université des Antilles\, in the French West Indies\, studying biology and tropical ecology in the Indian Ocean and Caribbean. Jean-Marie then continued to pursue his Postdoctoral research at University of Vienna\, Austria during 2012-2017. Initially in the Monika Bright´s Lab at the Department of Limnology and Biological Oceanography studying symbiosis in chemosynthetic ecosystems\, and then also in the Silvia Bulgheresi´s Lab at the Archea Biology and Ecogenomics Division studying tropical ecology pathways of microorganisms. In 2018 Jean-Marie joined the Berkeley Lab as an affiliate Scientist to continue working on uncovering highly divergent forms of life together with LRC Systems. The story of the discovery of Thiomargarita magnifica dates back a decade ago\, when marine biologist Olivier Gros\, from the Université of Antilles\, first discovered microbial filaments on leaves buried in the mangrove of Guadeloupe. Gros lab member and microbiologist colleague Silvina González-Rizzo identified it to be in fact be one bacterium. Jean-Marie\, together with his Université of Antilles colleagues and LRC Systems set forth to methodologically study and categorize the new organism. \n\n\n\n\n\n\n\nShailesh Date is the CEO and Founder of Laboratory for Research in Complex Systems (LRC Systems). He is also Adjunct Professor of Biology at San Francisco State University and an Associate Adjunct Professor of Epidemiology and Biostatistics at the University of California San Francisco (UCSF). Shailesh obtained his PhD at The University of Texas\, Austin in Molecular Biology in 2004\, and completed a postdoctoral fellowship at the University of Pennsylvania School of Medicine in 2008\, focusing on computational biology of infectious diseases. Between 2008-2015\, Shailesh worked as a scientist at Genentech\, and during a brief sabbatical in 2013\, completed the prestigious Ignite Program at the Stanford Graduate School of Business. He left Genentech in 2015 to join Global Viral (GV)\, a nonprofit organization with roots in public health research. He founded the LRC Systems in 2019\, transforming Global Viral into a new organization focused on complex systems research in a wide variety of areas. \n\n\n\nAbout Global Viral and LRC SystemsGlobal Viral was founded by Nathan Wolfe in 2007 as the Global Viral Forecasting Initiative (GVFI)\, focusing on public health and field epidemiology while supporting programs like HIV prevention run by USAID\, WHO and other similar organizations in Africa and South East Asia.In 2012\, the organization split into Metabiota\, a for-profit company that took over epidemiology and forecasting-related work\, and Global Viral\, a nonprofit that retained and concentrated on basic research.In 2019\, under the leadership of a new Chief Executive and a new board\, the organization reoriented its research towards complex systems and adopted the “Laboratory for Research in Complex Systems (LRC Systems)”\, which was initially founded as a new division within GV\, as its new name.https://www.lrc.systems \n\n\n\n\n\n\n\n\n“Clinical Talks” has been renewed for yet another exciting\, innovative\, and enlightening season. This season will focus on sustainable innovations within Life Sciences\, that have the potential to contribute to a better climate friendly future for our future generations. Also new this year is that the seminar is co-organized in a collaboration between SciLifeLab and KI Innovations . \n\n\n\nSeason 5\, will be held September 2021 until March 2022 with scheduled Talks\, during Friday mornings 09-09:30 am via ZOOM (with some time-zone friendly adjustments for our international speakers). Each session consists of a talk given by our invited speaker followed by Q&A. The seminar is an open educational seminar series for our ever-expanding Life Science community.
URL:https://www.scilifelab.se/event/seeing-is-believing-unraveling-the-discovery-of-ca-thiomargarita-magnifica-a-centimeter-long-macro-bacteria/
LOCATION:Online event via Zoom
CATEGORIES:Event
ORGANIZER;CN="Clinical Talks":MAILTO:precisionmedicine@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220411T151500
DTEND;TZID=Europe/Stockholm:20220411T161500
DTSTAMP:20260408T004219
CREATED:20220315T160745Z
LAST-MODIFIED:20220404T080634Z
UID:10000558-1649690100-1649693700@www.scilifelab.se
SUMMARY:Decreased levels of oxygen radicals cause autoimmune disease.
DESCRIPTION:Prof. Rikard Holmdahl \n\n\n\nKarolinska Institute\, Sweden \n\n\n\nRegister HERE\n\n\n\nRikard Holmdahl made his PhD (1985) and MD (1987) at Uppsala University. Professor in medical inflammation research Lund University 93-07. Professor at Karolinska Institute from 2008 \n\n\n\n\n\n\n\nVenue: Hybrid meeting – Trippelrummet\, Navet and zoom \n\n\n\n\n\n\n\n\n\n \n\n\n\nTitle of the seminar: Finding and understanding genes associated with common diseases; decreased levels of oxygen radicals cause autoimmune disease\n\n\n\nA long-standing challenge is to understand which genes that cause common complex diseases\, such as rheumatoid arthritis\, atherosclerosis or cancer\, and thereby understand the disease causes. However\, even though we know the human sequence and can genotype millions of individuals it is very difficult to conclusively identify the single nucleotide variants that cause the diseases. We have taken another approach through animal models. Both genetics and diseases show similarities with humans\, and we have shown that it is possible to not only identify the loci associated with disease but also exactly position the polymorphic nucleotides for common autoimmune diseases such as rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE).  \n\n\n\nI will focus on the first gene that we cloned\, Ncf1\, which regulate immune tolerance through different levels of oxygen radicals\, or more precisely hydrogen peroxide. It is the major gene causing SLE and is important in Sjögren’s syndrome and RA and most likely most autoimmune disease. \n\n\n\nTo understand the role of Ncf1 is also complicated as peroxide seem to regulate many different pathways leading to autoimmune diseases. I will discuss how we think it regulates RA and SLE but also how it could explain our normal behaviour\, thus explaining why Ncf1 variants are common in both rat and human population. \n\n\n\nRead more about ikard Holmdahl´s research http://ki.se/en/mbb/research-division-of-medical-inflammation-research
URL:https://www.scilifelab.se/event/decreased-levels-of-oxygen-radicals-cause-autoimmune-disease/
LOCATION:Navet\, SciLifeLab Uppsala\, SciLifeLab Uppsala\, BMC C11\, Husargatan 3\, Uppsala\, 75237\, Sweden
CATEGORIES:Event
ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2022/02/Picture1-The-Svedberg.png
ORGANIZER;CN="The Svedberg Seminar Series":MAILTO:thesvedberg@scilifelab.uu.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220412T003000
DTEND;TZID=Europe/Stockholm:20220412T010000
DTSTAMP:20260408T004219
CREATED:20220412T121106Z
LAST-MODIFIED:20220715T121407Z
UID:10000582-1649723400-1649725200@www.scilifelab.se
SUMMARY:γδSTO workshop –  Mini-symposium of Stockholm’s γδ T cell community
DESCRIPTION:A workshop on the May 5\, on gamma delta T cells for our scientific community in Stockholm. Different labs from SciLifeLab\, KI (Solna and Fleminsberg) and Stockholm University are invited. \n\n\n\nProgram: \n\n\n\n13:15 / Introduction \n\n\n\nTaras Kreslavskiy(KI): Transcriptome-wide screen for γδTCR specificities identifies a novel superantigen-like ligand candidate for Vγ7 γδTCRs \n\n\n\nLola Boutin (KI): Evaluation of the potential of using non-conventional (NC) T cell- based immunotherapy in Medulloblastoma \n\n\n\nPatrick Sandoz (KTH): Dynamics of Vγ9Vδ2 T cell cytotoxic functions at the single-cell level \n\n\n\n14:30 / Coffee break \n\n\n\nFaisal Alagrafi (KI):γδ T cells reconstitution in long term survivors after hematopoietic stem cell transplantation \n\n\n\nClàudiaArasa(SU): Functional characteristics of γδ T cells in prematurity and early life\, and their response to staphylococcal enterotoxins \n\n\n\nJulius Lautenbach (KI): Systems level analysis indicates an interplay between cytophilic antibodies\, monocytes\, and γδ T cells in malaria tolerance \n\n\n\n16:15 / Drinks and Discussion (γ2 lunchroom)
URL:https://www.scilifelab.se/event/%ce%b3%ce%b4sto-workshop-mini-symposium-of-stockholms-%ce%b3%ce%b4-t-cell-community/
LOCATION:Navet\, SciLifeLab Uppsala\, SciLifeLab Uppsala\, BMC C11\, Husargatan 3\, Uppsala\, 75237\, Sweden
CATEGORIES:Event
ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2022/03/infrastructure.png
ORGANIZER;CN="SciLifeLab Data Centre":MAILTO:datacentre@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220413T151500
DTEND;TZID=Europe/Stockholm:20220413T164500
DTSTAMP:20260408T004219
CREATED:20220315T132014Z
LAST-MODIFIED:20220331T120240Z
UID:10000555-1649862900-1649868300@www.scilifelab.se
SUMMARY:SciLifeLab COVID-19 seminar: Jinal Bhiman and Vicent Pelechano
DESCRIPTION:Topic: Detection of virus \n\n\n\nThe second SciLifeLab COVID-19 seminar this spring starts with Jinal Bhiman\, PhD and Scientific lead for the Global Immunology and Immune Sequencing South Africa (GIISER-SA)\, talking about SARS-CoV-2 viral evolution in South Africa and hybrid immunity profiles. Vicent Pelechano\, PhD\, SciLifeLab and Wallenberg Academy Fellow and Principal Researcher at Karolinska Institutet\, then continues the seminar with his talk on Development of LAMP-based point of care strategies for simplified SARS-CoV-2 detection \n\n\n\n\n\n\n\nSchedule \n\n\n\n15:15- 16:00 – SARS-CoV-2 viral evolution in South Africa and hybrid immunity profiles                        Jinal Bhiman\, PhD and Scientific lead for the Global Immunology and Immune Sequencing South Africa (GIISER-SA)16:00-16:45 – Development of LAMP-based point of care strategies for simplified SARS-CoV-2 detection                       Vicent Pelechano\, PhD\, SciLifeLab and Wallenberg Academy Fellow and Principal Researcher at Karolinska Institutet\n\n\n\n\n\n\n\nRegistration is mandatory to get the Zoom link for the event  \n\n\n\n\nREGISTRATION\n\n\n\nBIOS & ABSTRACTS
URL:https://www.scilifelab.se/event/scilifelab-covid-19-seminar-jinal-bhiman-and-vicent-pelechano-online/
LOCATION:Online event via Zoom
CATEGORIES:Event
ATTACH;FMTTYPE=image/jpeg:https://www.scilifelab.se/wp-content/uploads/2021/05/covid_3d_model-min-1536x864-1.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220421T110000
DTEND;TZID=Europe/Stockholm:20220421T120000
DTSTAMP:20260408T004219
CREATED:20220323T161559Z
LAST-MODIFIED:20220323T161633Z
UID:10000567-1650538800-1650542400@www.scilifelab.se
SUMMARY:WGS & WTS – gamechangers in AML and ALL diagnostics
DESCRIPTION:Speaker: Manja Meggendorfer\, Head of Molecular Genetics at MLL Munich Leukemia Laboratory \n\n\n\nThe webinar is jointly organized by the Unit of Clinical Genetics at the Department of Molecular Medicine\, KI\, the Clinical Genomics platform and Genomic Medicine Sweden. \n\n\n\n \n\n\n\nRegister to receive zoom link
URL:https://www.scilifelab.se/event/wgs-wts-gamechangers-in-aml-and-all-diagnostics/
LOCATION:Online event via Zoom
CATEGORIES:Event
ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2022/03/Seminar_Manja-Meggendorfer.png
ORGANIZER;CN="Clinical Genomics Platform":MAILTO:marcela.davila@gu.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220421T150000
DTEND;TZID=Europe/Stockholm:20220421T160000
DTSTAMP:20260408T004219
CREATED:20220330T110000Z
LAST-MODIFIED:20220421T112532Z
UID:10000573-1650553200-1650556800@www.scilifelab.se
SUMMARY:FAIRPoints-Things you need to know about Data Access Statements
DESCRIPTION:Location: Online via Zoom \n\n\n\n\n\nSee Event in your Time Zone \n\n\n\nSpeaker: Juliane Schneider & Chris Erdmann \n\n\n\nSpeakers Juliane Bio\, Chris Bio \n\n\n\nFAIRPoints is an event series highlighting pragmatic measures developed by the community towards the implementation of the FAIR (Findable\, Accessible\, Interoperable\, Reusable) data principles\, in collaboration with GoFAIR US\, SDSC\, AGU\, and SciLifeLab Data Centre.  \n\n\n\nData access statements (DAS)\, also known as data availability statements\, are key elements that can be used in multiple diverse disciplines and have a huge impact in providing essential information as it outlines where and how any underlying data may be accessed and reused\, listing specific restrictions (if any) and authorization requirements. It is therefore integral to the FAIRification process.  \n\n\n\nJoin us in this talk to discover how an effective data access statement should look like!  \n\n\n\n\n\n\n\nRegister here\n\n\n\nSign up for future events here \n\n\n\nTwitter: @FAIR_Points
URL:https://www.scilifelab.se/event/fairpoints-das/
LOCATION:Online event via Zoom
CATEGORIES:Event
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220422T090000
DTEND;TZID=Europe/Stockholm:20220422T093000
DTSTAMP:20260408T004219
CREATED:20220330T133354Z
LAST-MODIFIED:20220405T153635Z
UID:10000575-1650618000-1650619800@www.scilifelab.se
SUMMARY:[Clinical Talks] Introduction to AI-driven image analysis in pathology: from preclinical research to clinical diagnostics
DESCRIPTION:Dr. Sami Blom leads Aiforia’s application development team with an ambition to build impactful image analysis solutions to advance histopathology. He has a background in the fields of translational cancer research and pathology and he has extensive expertise in staining and imaging methods for histology specimens. Dr. Blom joined Aiforia in 2016 to develop and advance Aiforia’s applications\, products and services. \n\n\n\nIntroduction to AI-driven image analysis in pathology: from preclinical research to clinical diagnostics \n\n\n\nAiforia equips pathologists and scientists with powerful deep learning artificial intelligence for translating images into discoveries\, decisions\, and diagnoses. The cloud based Aiforia software aims to escalate the efficiency and precision of preclinical and clinical medical image analysis from oncology to neuroscience and more. Deep learning artificial intelligence enables increased speed\, accuracy and consistency in medical image analysis.  \n\n\n\nAiforia was founded in 2013 and our mission is to provide the highest quality solutions for AI-assisted image analysis to enable personalized and democratized care for patients. Year 2021 was historic for the company: Aiforia was listed on Nasdaq Helsinki First North Market Finland in December 2021. In connection with the listing\, the Company raised approximately 29 million euros in gross assets. This\, together with the B-financing round implemented earlier in the same year\, provides a strong foundation for Aiforia’s growth. \n\n\n\nRegister to receive zoom link\n\n\n\n \n\n\n\n\n“Clinical Talks” has been renewed for yet another exciting\, innovative\, and enlightening season. This season will focus on sustainable innovations within Life Sciences\, that have the potential to contribute to a better climate friendly future for our future generations. Also new this year is that the seminar is co-organized in a collaboration between SciLifeLab and KI Innovations . \n\n\n\nSeason 5\, will be held September 2021 until March 2022 with scheduled Talks\, during Friday mornings 09-09:30 am via ZOOM (with some time-zone friendly adjustments for our international speakers). Each session consists of a talk given by our invited speaker followed by Q&A. The seminar is an open educational seminar series for our ever-expanding Life Science community.
URL:https://www.scilifelab.se/event/clinical-talks-introduction-to-ai-driven-image-analysis-in-pathology/
LOCATION:Online event via Zoom
CATEGORIES:Event
ORGANIZER;CN="Clinical Talks":MAILTO:precisionmedicine@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220426T093000
DTEND;TZID=Europe/Stockholm:20220426T120000
DTSTAMP:20260408T004219
CREATED:20220411T114853Z
LAST-MODIFIED:20220411T115121Z
UID:10000581-1650965400-1650974400@www.scilifelab.se
SUMMARY:New developments in upstream bioprocessing technologies seminar
DESCRIPTION:Presentation och demonstration av nya single use bioreactors (SUB) för mammalieceller.  \n\n\n\nregister to attend\n\n\n\nProgram:  \n\n\n\n9:30-10:15 Matthijs Neimeijer\, Cultivating red blood cells in singe-use bioreactors \n\n\n\n10:15-10:45 Fika och demonstration \n\n\n\n10:45-11:30 Michel Kensler\, Comparisons in scale up and down scale \n\n\n\n11:30-12:00 Questions
URL:https://www.scilifelab.se/event/new-developments-in-upstream-bioprocessing-technologies-seminar/
LOCATION:Air&Fire\, SciLifeLab Stockholm\, Tomtebodavägen 23A\, Solna\, Sweden
CATEGORIES:Event
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220426T120000
DTEND;TZID=Europe/Stockholm:20220426T130000
DTSTAMP:20260408T004219
CREATED:20220411T113030Z
LAST-MODIFIED:20220411T113031Z
UID:10000580-1650974400-1650978000@www.scilifelab.se
SUMMARY:Measuring metabolites\, the building blocks of biology
DESCRIPTION:In the frame of the SciLifeLab Site Umeå / KBC Infrastructure Seminar Series\, the seminars will be organised every second Tuesday during spring 2022 in turn with IceLab Lunch Pitches. The seminars will be held in a hybrid format IRL in Glasburen\, KBC\, and online via Zoom. Take the chance to get information on facilities\, possibilities and services that infrastructure\, both SciLifeLab-associated and local\, can offer! Learn more about the seminar series and Schedule for Spring 2022 here. \n\n\n\nOn April 26th\, 12:00-13:00\, SciLifeLab Site Umeå / KBC Infrastructure Seminar Series presents:  \n\n\n\n“Measuring metabolites\, the building blocks of biology” \n\n\n\nby Annika Johansson\, Head of the Swedish Metabolomics Centre (SMC) facility. \n\n\n\nThe presentation will give an introduction to metabolomics and small molecule analysis by mass spectrometry. We will present our different services and also give examples of different research projects in which SMC has been involved. \n\n\n\nLearn more about the Swedish Metabolomics Centre on its homepage. \n\n\n\nSign up (latest by April 25th\, 10 a.m.) for on-site participation or follow online via Zoom: https://umu.zoom.us/j/63138997026 \n\n\n\nregistration
URL:https://www.scilifelab.se/event/measuring-metabolites-the-building-blocks-of-biology/
LOCATION:Glasburen Seminar Room\, Chemical Biological Centre (KBC) Building\, Umeå University\, Umeå\, 901 87\, Sweden
CATEGORIES:Event
ORGANIZER;CN="SciLifeLab Ume%C3%A5":MAILTO:umea@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220427T140000
DTEND;TZID=Europe/Stockholm:20220427T153000
DTSTAMP:20260408T004219
CREATED:20220420T102001Z
LAST-MODIFIED:20220420T102506Z
UID:10000584-1651068000-1651073400@www.scilifelab.se
SUMMARY:Developmental origins of cell heterogeneity in the human lung
DESCRIPTION:HDCA Seminar Series 2022 | Lung \nChristo Samakovlis and Alexandros Sountoulidis \nThe lung contains numerous specialized cell-types with distinct roles in tissue function and integrity. To clarify the origins and mechanisms generating cell heterogeneity\, we created a first comprehensive topographic atlas of early human lung development. We report 83 cell states\, several spatially-resolved developmental trajectories and predict cell interactions within defined tissue niches. We integrated scRNA-Seq and spatial transcriptomics into a web-based\, open platform for interactive exploration. To illustrate the utility of our approach we show distinct states of secretory and neuroendocrine cells\, largely overlapping with the programs activated either during lung fibrosis or small cell lung cancer progression. We define the origin of uncharacterized airway fibroblasts associated with airway smooth muscle in bronchovascular bundles\, and describe a trajectory of Schwann cell progenitors to intrinsic parasympathetic neurons controlling bronchoconstriction. Our atlas provides a rich resource for further research and a reference for defining deviations from homeostatic and repair mechanisms leading to pulmonary diseases. \n  \n– \nHuman developmental cell atlas (HDCA) is the Swedish effort within the human cell atlas (HCA)\, one of the largest international scientific projects. The project aim is to create a comprehensive molecular atlas of human prenatal development at the molecular resolution using state-of-the-art multi-omic technologies such as single-cell RNA-seq\, Spatial Transcriptomics\, in situ sequencing in order to provide deeper insight into how variations and deviations contribute to health and disease. \nThe HDCA Seminar Series 2022 invites you to join us on a journey of early human organogenesis of several organs at the single-cell and spatial resolution. Seminars will be held at SciLifeLab Gamma building on Wednesdays at 14:00 or 15:00 and also via Zoom. After each seminar\, we will have up to 30 min round up discussions with the speaker on how you can contribute to the atlas!  \nWarm Welcome! \n  \n\n\nregistration
URL:https://www.scilifelab.se/event/developmental-origins-of-cell-heterogeneity-in-the-human-lung/
LOCATION:Gamma 2 Lunchroom\, SciLifeLab\, Tomtebodavägen 23\, Solna\, Sweden
CATEGORIES:Event
ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2022/04/logo_hdca2.png
ORGANIZER;CN="The Human Developmental Cell Atlas":MAILTO:hdca-sweden@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220428T080000
DTEND;TZID=Europe/Stockholm:20220429T170000
DTSTAMP:20260408T004219
CREATED:20220308T124733Z
LAST-MODIFIED:20220308T142609Z
UID:10000547-1651132800-1651251600@www.scilifelab.se
SUMMARY:Nordic Precision Medicine Forum
DESCRIPTION:Just prior to the pandemic Sweden launched its first ever national Life Science Strategy in eight priority areas covering the strengthening of academic research\, facilitating collaboration between academia and industry\, attracting more industry initiated clinical trials\, and the continuous skills development needed for precision medicine and highly advanced production of pharmaceuticals and medtech devices. Across the Nordic countries precision medicine and technology developments continue at pace\, truly putting them in a favourable position when it comes to taking on the opportunities and challenges of implementing precision medicine\, with its promise to really transform future healthcare as well as the entire life science sector. \n\n\n\nSince 2016 we have convened the regions leading scientists\, healthcare practitioners\, and industry pioneers at our annual meeting. For 2022 you can expect a whole lot more interaction as we finally get back to in-person events. \n\n\n\nRead more\n\n\n\nWe very much hope to see you in Stockholm in April 2022 and hope that you and your loved ones remain safe and healthy throughout these troubling times.
URL:https://www.scilifelab.se/event/nordic-precision-medicine-forum/
LOCATION:Hotel Birger Jarl\, Birger Jarlsgatan 61\, Stockholm\, Sweden
CATEGORIES:Event
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220428T170000
DTEND;TZID=Europe/Stockholm:20220428T190000
DTSTAMP:20260408T004219
CREATED:20220420T143019Z
LAST-MODIFIED:20220420T143132Z
UID:10000587-1651165200-1651172400@www.scilifelab.se
SUMMARY:Matchmaking Event – Data Science and Medical/Clinical Research
DESCRIPTION:Welcome to a matchmaking event between researchers within Data Science and Medical/Clinical research at KTH and Region Stockholm. The event is related to the project call: Health\, Medicine and Technology 2023. \n\n\n\nRead more\n\n\n\nRegion Stockholm and KTH opened the yearly call for collaboration in Health\, Medicine and Technology 14 April\, 2022. A key requirement to apply for this call is that one of the partners should be from KTH and one from Region Stockholm. With this event\, we hope to encourage collaborations between experts in data science and clinical research\, at KTH and Region Stockholm. The event is open for all researchers from KTH and from Region Stockholm who are eligible to submit a grant proposal for the Health\, Medicine and Technology Project Call. Postdoctoral researchers who can be co-PI are also encouraged to attend the event. Should you have any questions\, please contact: lifescienceplatform@kth.se ordigitalizationplatform@kth.se \n\n\n\nThe event is organised by the KTH Life Science Platform and KTH Digitalization Platform
URL:https://www.scilifelab.se/event/matchmaking-event-data-science-and-medical-clinical-research/
LOCATION:Air&Fire\, SciLifeLab Stockholm\, Tomtebodavägen 23A\, Solna\, Sweden
CATEGORIES:Event
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220429T140000
DTEND;TZID=Europe/Stockholm:20220429T150000
DTSTAMP:20260408T004219
CREATED:20220315T091430Z
LAST-MODIFIED:20220315T134837Z
UID:10000553-1651240800-1651244400@www.scilifelab.se
SUMMARY:AI-driven genomic precision diagnostics in hematologic malignancies
DESCRIPTION:In this webinar\, jointly organized by the Clinical Genomics platform and Genomic Medicine Sweden\, Dr. Aziz Nazha will present AI-based solutions to improve the diagnosis\, prognosis\, and selection of therapy in hematologic malignancies. The talk will also cover the clinical implication of AI/ML in diagnostic hematology\, current challenges and potential future opportunities. \n\n\n\n\n\n\n\nRegister to receive zoom link\n\n\n\n\n\n\n\nHost: Thoas Fioretos\, Director Clinical Genomics platform \n\n\n\nShort bio:  Aziz Nazha\, MD\, is currently a Global Tech Business Development for Healthcare Solutions at Amazon Web Services. Prior to joining Amazon\, Dr. Nazha was the director of the Cleveland Clinic Center for Clinical Artificial Intelligence and an Associate Medical Director at Enterprise Analytics. He is also an internationally recognized expert in treating patients with leukemia. His research focuses on the use of artificial intelligence\, machine learning\, and deep learning to translate genomic and complex healthcare data into useful clinical tools that can improve patient outcomes.
URL:https://www.scilifelab.se/event/ai-driven-genomic-precision-diagnostics-in-hematologic-malignancies/
LOCATION:Online event via Zoom
CATEGORIES:Event
ATTACH;FMTTYPE=image/jpeg:https://www.scilifelab.se/wp-content/uploads/2022/03/Banner-Clinical-Genomics-GMS.jpg
ORGANIZER;CN="Clinical Genomics Platform":MAILTO:marcela.davila@gu.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220502T151500
DTEND;TZID=Europe/Stockholm:20220502T161500
DTSTAMP:20260408T004219
CREATED:20220422T104856Z
LAST-MODIFIED:20220422T111337Z
UID:10000590-1651504500-1651508100@www.scilifelab.se
SUMMARY:The use of systems biology in treatment of liver diseases
DESCRIPTION:Adil Mardinoglu\, Assoc. Prof.KTH SwendenKing s College London\, UK\n\n\n\n \n\n\n\nRegister here to get the zoom link\n\n\n\nAssoc. Prof. Adil Mardinoglu is an expert in the field of Systems Medicine\, Systems Biology\, Computational Biology and Bioinformatics. He lead a team of 25 researchers working in the area of computational biology\, experimental biology and drug development to develop new treatment strategies for Metabolic diseases\, Neurodegenerative diseases and certain type of cancers  \n\n\n\n Abstract: Biological networks can provide a scaffold for studying biological pathways operating in the liver in connection with disease development in a systematic manner. In my presentation\, I will present our recent work where biological networks have been employed to identify the reprogramming in liver physiology in response to NASH/NAFLD. I will further discuss how this mechanistic modelling approach can contribute to the discovery of biomarkers and identification of drug targets which may lead to design of targeted and effective personalized medicine. \n\n\n\nWebpage: https://sysmedicine.com/
URL:https://www.scilifelab.se/event/adil-mardinoglu/
LOCATION:Online event via Zoom
CATEGORIES:Event
ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2022/02/Picture1-The-Svedberg.png
ORGANIZER;CN="The Svedberg Seminar Series":MAILTO:thesvedberg@scilifelab.uu.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220503T090000
DTEND;TZID=Europe/Stockholm:20220503T120000
DTSTAMP:20260408T004219
CREATED:20220121T160156Z
LAST-MODIFIED:20220121T160157Z
UID:10000514-1651568400-1651579200@www.scilifelab.se
SUMMARY:BioImage Analysis support - Call4Help
DESCRIPTION:Every 1st week of the month (mainly on Tuesdays\, but there might be exceptions) the BioImage Informatics Facility together with microscopy expert Sylvie Le Guyader (LCI\, Karolinska Institutet) organizes a Call4Help session. The aim is to offer combined expertise towards microscopy and bioimage analysis. All researchers from Swedish institutes can participate. \n\n\n\nThe ideal timepoint to join the Call4Help session is when a researcher has performed pilot experiments and has tried out first analysis approaches – but before having recorded hundreds of images. Combining BIIF’s expertise in BioImage Analysis with microscopy expertise we can discuss ways to record the images that allow analysis afterwards. We will discuss different analysis approaches using mainly open-source software (Fiji\, CellProfiler\, QuPath\, Ilastik\, KNIME)\, but also commercial systems\, if needed (Imaris). \n\n\n\nThe Call4Help session format has been introduced to the BioImage Analysis community by NEUBIAS and ScopeM. \n\n\n\nHow to participate? \n\n\n\nStep1: \n\n\n\nPrepare a short presentation (5-7 min)  – use the following template for your presentation: \n\n\n\nhttp://bit.ly/BIIF_C4H_slideTemplate \n\n\n\nSlide template by NEUBIAS/ScopeM \n\n\n\nStep2: \n\n\n\na) Upload your presentation \n\n\n\nUpload your presentation to a drive of your choice. You can also use our Call4Help google drive. Note that files shared on our Call4Help drive will be available to everyone until the session is over. \n\n\n\nhttp://bit.ly/BIIF_C4H_Drive \n\n\n\nb) Upload example images for testing. \n\n\n\nUpload example images for testing either to the drive of your choice or our Call4Help google drive above. \n\n\n\nhttp://bit.ly/BIIF_C4H_Drive \n\n\n\nc) Register by filling out the registration form: \n\n\n\nhttp://bit.ly/BIIF_C4H_Registration \n\n\n\nStep 3: \n\n\n\nJoin the zoom-session. \n\n\n\nIf your problem is selected for presentation\, you will get a time-slot of 30 – 60 minutes within the session. \n\n\n\nWhat are the Deadlines \n\n\n\nSubmission of a problem and upload of example data: Friday the week before the session. \n\n\n\nNotification about participation: The day before the session. \n\n\n\nNext Call4Help session \n\n\n\nTuesday\, May 3\, 2022\, 9.00-12.00. Deadline for application: Friday\, April 29\, 2022.
URL:https://www.scilifelab.se/event/bioimage-analysis-support-call4help-4/
LOCATION:Online event via Zoom
CATEGORIES:Event
ORGANIZER;CN="Bioimage Informatics Unit":MAILTO:biif@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220505T130000
DTEND;TZID=Europe/Stockholm:20220505T170000
DTSTAMP:20260408T004219
CREATED:20211202T101312Z
LAST-MODIFIED:20220504T152450Z
UID:10000495-1651755600-1651770000@www.scilifelab.se
SUMMARY:γδSTO workshop -  Mini-symposium of Stockholm’s γδ T cell community
DESCRIPTION:A workshop on the May 5\, on gamma delta T cells for our scientific community in Stockholm. Different labs from SciLifeLab\, KI (Solna and Fleminsberg) and Stockholm University are invited. \n\n\n\nregister to attend\n\n\n\nProgram: \n\n\n\nγδSTO-workshop-programDownload
URL:https://www.scilifelab.se/event/%ce%b3%ce%b4sto-workshop/
LOCATION:Air&Fire\, SciLifeLab Stockholm\, Tomtebodavägen 23A\, Solna\, Sweden
CATEGORIES:Community,Event
ORGANIZER;CN="Patrick Sandoz":MAILTO:patrick.sandoz@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220505T150000
DTEND;TZID=Europe/Stockholm:20220505T160000
DTSTAMP:20260408T004219
CREATED:20220428T154038Z
LAST-MODIFIED:20220428T154048Z
UID:10000597-1651762800-1651766400@www.scilifelab.se
SUMMARY:BAM Seminar: From memes to wordplay – How to add humor to your science communication
DESCRIPTION:‘First make people laugh\, and then make them think’. Humor can be a powerful way to attract attention and convey your message. However\, it is also challenging to find the right balance between funny quips and scientific content. In this talk\, Jente Ottenburghs will share some tips and tricks on how he has managed to blend stand-up comedy and science communication. \n\n\n\nJente Ottenburghs\, is a lecturer at University of Wageningen. He worked as a Postdoc at Karolinska Institutet and Uppsala University after he obtained his PhD from University of Wageningen. Throughout his career\, he experimented with different ways of Science communication and also did stand-up comedy.  \n\n\n\nResearchers in all stages of their career\, who want to spice up their talks\, are welcome to attend and could find the talk useful. Branching out in the ways to present one’s research can make talks more interesting and memorable and can help to convey the messages to the audience.  
URL:https://www.scilifelab.se/event/from-memes-to-wordplay-how-to-add-humor-to-your-science-communication/
LOCATION:Online event via Zoom
CATEGORIES:Event
ORGANIZER;CN="SciLifeLab Solna PhD & Postdoc Council":MAILTO:phd-council@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220506T090000
DTEND;TZID=Europe/Stockholm:20220506T093000
DTSTAMP:20260408T004219
CREATED:20220217T115711Z
LAST-MODIFIED:20220331T141218Z
UID:10000531-1651827600-1651829400@www.scilifelab.se
SUMMARY:[Clinical Talks] iCAN and developing a national precision cancer medicine program
DESCRIPTION:On May 6\, Professor Tomi Mäkelä at the University of Helsinki Faculty of Medicine will talk about his work as executive officer of the iCAN Digital Precision Cancer Medicine flagship. iCAN is one of the Academy of Finland national research and innovation flagships for 2019-2026\, with the goal to develop a nucleus of scientific excellence into competence clusters for discoveries\, innovations\, and societal and economic impact. The founding hosts are the University of Helsinki and HUS Helsinki University Hospital with a goal for national reach within the National Cancer Center FICAN. While executed as a public-private-patient-partnership\, iCAN brings together academic research\, healthcare system\, life science industry partners and patients. The active participation of patients at all levels is a key element of the flagship\, ensuring impact and benefits to the patients. Partnerships with companies from pharma\, biotech\, and AI sectors are critical and enable the inclusion of early drug leads\, new technologies\, and new competencies. Furthermore\, iCAN leverages the unique strengths that Finland has in the areas of top-level cancer research\, health registries\, biobanks\, and digital health to provide solutions for the global cancer challenge. \n\n\n\nRegistration\n\n\n\nTomi Mäkelä\, MD\, PhD\, is a Professor of Biochemistry and Molecular Biology at the University of Helsinki Faculty of Medicine\, and the Executive Officer of the Finish iCAN Digital Precision Cancer Medicine flagship program. He obtained an MD and PhD in Oncology and Cancer Biology during his studies in the late 80\, early 90s at the University of Helsinki. He then pursued his postdoctoral studies at the prestigious Whitehead Institute\, Cambridge Massachusetts 1993-1995\, and in 2002 became a Professor at the University of Helsinki. Since\, then he has held various leadership positions at the University\, including\, Director of the Institute of Biotechnology (2009-2014)\, Director of HiLIFE Helsiniki Institute of Life Science (2015-2019)\, Director of Biomedicum Helsinki (2017-present). Prof. Mäkelä is also the current Executive Manager of The Finnish Cancer Institute (since 2012)\, and a panelist and panel chair of the European Research Council since 2011. \n\n\n\nThe iCAN Digital Precision Cancer Medicine flagship is one of six national flagships in Finland 2019-2026 aiming to develop nuclei of scientific excellence into competence clusters for discoveries\, innovations\, and societal and economic impact. In iCAN a platform joining Precision Cancer Medicine (PCM) with Digital Health is established for discoveries and improved treatments. iCAN is hosted by the University of Helsinki and Helsinki University Hospital HUS and with a goal for national reach within the National Cancer Center FICAN. Leveraging the unique strengths that Finland has in the areas of top-level cancer research\, health registries\, biobanks\, and digital health to provide solutions for the global cancer challenge. iCAN is furthermore organized as a partnership between academic research\, healthcare system\, life science industry partners and patients. It is a public-private-patient-partnership\, forming a competence cluster with significant economic\, educational\, and societal impact. The active participation of patients at all levels is a key element of the flagship\, ensuring impact and benefits to the patients. Partnerships with companies from pharma\, biotech\, and AI sectors are critical and enable the inclusion of early drug leads\, new technologies\, and new competencies. \n\n\n\nThese ambitious goals are accomplished via the unique iCAN digital precision cancer medicine platform\, enabling the integration of cutting-edge molecular profiling information from tumors with rich longitudinal health data available in Finland\, by eg. addressing tumor development in the context of the immune system or development of treatment resistance. The iCAN discovery platform links molecular profiling of tumors with broader health data of cancer patients\, acting as a catalyst for breakthrough research and technologies.The scale of data – 15\,000 samples across different cancer types will be profiled by 2026 – enables real impact and broad studies across different cancer types. The platform will enable an improved understanding of the complex interplay between cancer cells and the host.The pan-cancer research project already has ongoing studies in colorectal\, gastric\, pancreatic\, breast\, lung\, ovarian\, renal\, prostate\, bladder\, melanoma\, and pediatric solid cancers as well as myeloid leukemias\, lymphomas and multiple myeloma. \n\n\n\nRead more\n\n\n\n\n\n\n\n\n“Clinical Talks” has been renewed for yet another exciting\, innovative\, and enlightening season. This season will focus on sustainable innovations within Life Sciences\, that have the potential to contribute to a better climate friendly future for our future generations. Also new this year is that the seminar is co-organized in a collaboration between SciLifeLab and KI Innovations . \n\n\n\nSeason 5\, will be held September 2021 until March 2022 with scheduled Talks\, during Friday mornings 09-09:30 am via ZOOM (with some time-zone friendly adjustments for our international speakers). Each session consists of a talk given by our invited speaker followed by Q&A. The seminar is an open educational seminar series for our ever-expanding Life Science community.
URL:https://www.scilifelab.se/event/clinical-talks-ican-and-developing-a-national-precision-cancer-medicine-program/
LOCATION:Online event via Zoom
CATEGORIES:Event
ORGANIZER;CN="Clinical Talks":MAILTO:precisionmedicine@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220509T090000
DTEND;TZID=Europe/Stockholm:20220509T110000
DTSTAMP:20260408T004219
CREATED:20220315T124100Z
LAST-MODIFIED:20220715T121447Z
UID:10000554-1652086800-1652094000@www.scilifelab.se
SUMMARY:Open science & Reproducibility Services at SciLifeLab
DESCRIPTION:Time: 09:00-11:00Format: Zoom meeting will be recorded \n\n\n\nSciLifeLab Data Centre invites you to a 2-hour event on May 9th 2022 focusing on services available at SciLifeLab for researchers regarding Open Science and Reproducibility.  \n\n\n\nIn the event we will showcase a variety of tools and services to facilitate open and reproducible practices in data-driven research.  \n\n\n\nSpeakers: \n\n\n\nErik Fasterius\, NBISStephan Nylinder\, NBIS Data Management teamAnna Asklöf\, SciLifeLab Data Centre teamOla Spjuth\, prof.\, SciLifeLab\n\n\n\n\n\n\n\nRegister here\n\n\n\n\n\n\n\nDon’t forget to register to the afternoon event: \n\n\n\nexploring Open Science Pathways in the Earth\, Space\, and Life Sciences
URL:https://www.scilifelab.se/event/open-science-reproducibility-at-scilifelab/
LOCATION:Online event via Zoom
CATEGORIES:Event
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220509T120000
DTEND;TZID=Europe/Stockholm:20220509T170000
DTSTAMP:20260408T004219
CREATED:20220315T080000Z
LAST-MODIFIED:20220509T065057Z
UID:10000552-1652097600-1652115600@www.scilifelab.se
SUMMARY:Open Science Pathways in the Earth\, Space\, and Life Sciences
DESCRIPTION:SciLifeLab Data Centre and the American Geophysical Union (AGU) invite you to a half-day event on May 9th 2022 focusing on Open Science and Reproducibility.  \n\n\n\nTime: 12:00-17:00 Format: Zoom Webinar will be recorded. \n\n\n\nThis event will feature a number of speakers all addressing these themes on Open Science from various perspectives on a national and international level:  \n\n\n\nThe Path to Open\, Reproducible Science – Stories from the Research CommunityHow to Open Science – Practical Use Cases\, Lessons Learned from the Research CommunityOpen Science from a Broader Context – What Open Science Means from the National and International Perspectives\n\n\n\nSpeakerTitleTime in CESTJohan Rung- SciLifeLab-Data CentreIntroduction12:00Shelly Stall- American Geophysical UnionYour Journey Towards Open Science12:10-12:35Q&A12:35-12:40Sara El-Gebali- SciLifeLab-Data CentreThe road beyond open12:40-13:05Q&A13:05-13:10Break13:10-13:25Fredrik Ronquist- Swedish Museum of Natural History\, SciLifeLabFAIR and Open Science in the biodiversity research community13:25-13:50Q&A13:50-13:55David Diez del Molino- Swedish Museum of Natural HistoryGenome Erosion Pipeline13:55-14:20Q&A14:20-14:25Yuhan Douglas Rao- Cooperative Institute for Satellite and Earth System Studies / NC State University“If It Ain’t Broke\, Why Fix it?” – Open Science Lessons Learned in the Field14:25-14:50Q&A14:50-14:55Break14.55-15.10Daniel Bangert- Digital Repository of Ireland\, Royal Irish AcademyIreland’s national agenda for open research15:10-15:35Q&A15:35-15:40Christine Kirkpatrick- SDSC: San Diego SuperComputing CenterAn Open Science Future: National and International Perspectives15:40-16:05Q&A16:05-16:10Chelle Gentemann- NASAOpening up to Open Science16:10-16:35Q&A16:35-16:40Shelley StallClosing Remarks16:40-17:00\n\n\n\nRegister here
URL:https://www.scilifelab.se/event/agu-scilifelab/
LOCATION:Online event via Zoom
CATEGORIES:Event
ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2022/03/Artboard-1-1.png
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220509T151500
DTEND;TZID=Europe/Stockholm:20220509T160000
DTSTAMP:20260408T004219
CREATED:20220502T101150Z
LAST-MODIFIED:20220502T101852Z
UID:10000598-1652109300-1652112000@www.scilifelab.se
SUMMARY:The Svedberg seminar: Daniel Fürth
DESCRIPTION:Assistent Professor\, SciLifeLab Fellow at Uppsala University \n\n\n\nHybrid event: Trippelrummet\, Navet\, BMC and Online \n\n\n\n\n\n\n\n\n\nRegister here\n\n\n\nDr. Daniel Fürth completed his Ph.D. in neuroscience at Karolinska Institutet\, working on mesoscale connectomics using modified rabies virus tracing\, then postdoctoral work in RNA biology and method development at Cold Spring Harbor Laboratory\, Cancer Center\, New York. At Cold Spring Harbor he focused on enabling functional RNA genomics in situ at subcellular single-molecule resolution. Dr. Fürth’s expertise as a leader in both wet and dry lab neuroscience is internationally recognized with a Brain & Behavior Research Foundation NARSAD Young Investigator Award and computational funding from the Chan Zuckerberg Initiative. Dr. Fürth’s lab studies how information is stored\, processed and transmitted between cells. The focus is to find hitherto unknown mechanisms that can transfer symbolic information between cells. Identification of such transmission would enable us to read and write those messages.  \n\n\n\nTitle of the seminar: From in situ to in vivo sequencing\n\n\n\nUnbiased investigation of subcellular RNA localization and its control in vivo remains challenging. Current hybridization-based methods cannot differentiate small regulatory variants\, whilein situ sequencing is limited by short reads. We solved these problems using a bidirectional sequencing chemistry to efficiently image transcript-specific barcodes in situ\, which are then extracted and assembled into longer reads using NGS. Specific cis-regulatory elements usually found in mRNA 3′UTRs mediate RNA localization. Reverse transcription was primed towards the 3’UTR/polyA-tail junction in developing Drosophila and we discovered that in situ cDNA synthesis stalls just downstream of RNA-binding protein crosslink sites\, resulting in truncated cDNAs near RNA-binding protein motifs. We utilized these stop signatures to spatially map cis-regulatory motifs in specific alternative polyadenylation (APA) isoforms. A subset of genes displayed expression of two or more APA isoforms with distinct localization in situ\, to which we could identify their putative trans-acting partners. We validated our findings using both iCLIP-seq and targeted clampFISH probes. Our platform\, therefore\, provides a powerful way to discover novel RNA variants and protein interactions and their localization in situ. Lastly\, I’ll present recent developments of a fluorogenic and non-enzymatic sequencing chemistry capable of sequencing single molecules directly in live cells with subcellular precision.
URL:https://www.scilifelab.se/event/the-svedberg-seminar-daniel-furth/
LOCATION:Navet\, SciLifeLab Uppsala\, SciLifeLab Uppsala\, BMC C11\, Husargatan 3\, Uppsala\, 75237\, Sweden
CATEGORIES:Event
ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2022/04/Picture1-The-Svedberg-edited.png
ORGANIZER;CN="The Svedberg Seminar Series":MAILTO:thesvedberg@scilifelab.uu.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220510T120000
DTEND;TZID=Europe/Stockholm:20220510T130000
DTSTAMP:20260408T004219
CREATED:20220428T075520Z
LAST-MODIFIED:20220428T075524Z
UID:10000595-1652184000-1652187600@www.scilifelab.se
SUMMARY:National NMR Infrastructure at KBC. What can we do for you?
DESCRIPTION:In the frame of the “SciLifeLab Site Umeå / KBC Infrastructure Seminar Series”\, the seminars will be organised every second Tuesday during spring 2022 in turn with IceLab Lunch Pitches. The seminars will be held in a hybrid format IRL in Glasburen\, KBC\, and online via Zoom. Take the chance to get information on facilities\, possibilities and services that infrastructure\, both SciLifeLab-associated and local\, can offer! Learn more about the seminar series and Schedule for Spring 2022 here. \n\n\n\nOn May 10th\, 12:00-13:00\, SciLifeLab Site Umeå / KBC Infrastructure Seminar Series presents:  \n\n\n\n“National NMR Infrastructure at KBC. What can we do for you?” \n\n\n\nby Gerhard Gröbner\, Platform Director\, Professor\, Department of Chemistry\, Umeå University andJürgen Schleucher\, Platform Director\, Professor\, Department of Medical Biochemistry and Biophysics\, Umeå University \n\n\n\nSeminar description: The KBC based central NMR facility(Homepage) provides access to one of the most powerful liquid and solid-state NMR infrastructures in the Nordic countries and expertise for all researchers in the KBC and Campus environment. The facility serves large user groups spanning a remarkably wide range of fields\, such as materials science\, chemical biology\, organic synthesis\, structural biology\, plant- and environmental sciences\, biogeochemistry and medical metabolomics. Local researchers profit strongly from the facility’s status as a national infrastructure and different structural biology facilities and expertise (“Integrated Structure Biology”) at UMU. Fragment-based screening is also offered as national support in collaboration with CBCS/LCBU\, including comprehensive substance libraries. The facility is also closely linked to large research initiatives at the campus such as MIMS\, UCMP\, Bio4Energy\, UPSC\, the Swedish Metabolomics Center (SMC) and with SLU through collaborations and by offering service. \n\n\n\nActivities: If required\, a short guided tour to the NMR facility and drop-in discussions with NMR people about potential projects could be organised after the seminar. \n\n\n\nRegistration: \n\n\n\nSign up (latest by May 9th\, 10 a.m.) for on-site attendance to reserve your free lunch sandwich: \n\n\n\nor follow online via Zoom (registration is not required): https://umu.zoom.us/j/63138997026 . \n\n\n\nOrganisers: SciLifeLab Site Umeå and Chemical Biological Centre (KBC)
URL:https://www.scilifelab.se/event/national-nmr-infrastructure-at-kbc-what-can-we-do-for-you/
LOCATION:Glasburen Seminar Room\, Chemical Biological Centre (KBC) Building\, Umeå University\, Umeå\, 901 87\, Sweden
CATEGORIES:Event
ORGANIZER;CN="SciLifeLab Ume%C3%A5":MAILTO:umea@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220511T110000
DTEND;TZID=Europe/Stockholm:20220511T160000
DTSTAMP:20260408T004219
CREATED:20220425T081942Z
LAST-MODIFIED:20220427T142909Z
UID:10000593-1652266800-1652284800@www.scilifelab.se
SUMMARY:Spatial Biology Tour
DESCRIPTION:The Spatial proteomics unit together with Lunaphore invite you to a workshop to learn about their new instrument and service with the COMET platform. The Spatial proteomics unit is the first lab in Sweden to offer multiplexed protein detection with the COMET platform\, which relies on sequential indirect immunofluorescence using off the shelf primary antibodies. The workshop also allows for a guideed tour of the lab and an instrument demonstration. Lunch will be served for registered participants.  \n\n\n\nplease sign up here to attend
URL:https://www.scilifelab.se/event/spatial-biology-tour/
LOCATION:Air&Fire\, SciLifeLab Stockholm\, Tomtebodavägen 23A\, Solna\, Sweden
CATEGORIES:Event
ORGANIZER;CN="Spatial Proteomics Unit":MAILTO:spatial.proteomics@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220511T140000
DTEND;TZID=Europe/Stockholm:20220511T153000
DTSTAMP:20260408T004219
CREATED:20220426T132422Z
LAST-MODIFIED:20220507T113616Z
UID:10000594-1652277600-1652283000@www.scilifelab.se
SUMMARY:Decoding the development of the human spinal cord by multi-omics
DESCRIPTION:Decoding the development of the human spinal cord by multi-omics \n\n\n\nXiaofei Li and Erik Sundström \n\n\n\nHDCA Seminar Series 2022 | Spinal cord \n\n\n\nThe human spinal cord has highly diverse cell types\, which are generated during development\, governed by a series of temporal and spatial events for proper spinal cord assembly and function. However\, the molecular regulation of cell fate specification in the human developing spinal cord remains largely unknown. Here\, by performing single-cell RNA sequencing\, spatial transcriptomics and in situ sequencing\, we integrate the datasets and provide a comprehensive single-cell and spatial transcriptomic atlas of the developing human spinal cord of the first trimester\, from postconceptional week 5 to 12. We observe that all major cell populations in human adult spinal cord have been specified within the first trimester with abundant cell states\, and identify the key genes associated with cell fate choices and their spatial expression. Unexpectedly\, we find that during early cell fate specification\, many human neural progenitor cells have lost their self-renewal capacity. Further the the expression of gliogensis genes is much higher in human compared to the correspondent rodents at the early stage\, suggesting earlier gliogenesis in human. Finally\, we demonstrate how to use our developmental map for molecular cues that direct sequential cellular differentiation and define cells and locations associated to both normal development and spinal cord diseases. \n\n\n\nsign up to attend\n\n\n\nPlease register also if you want to participate in the digital broadcast. The Zoom link will be sent out through the registration system.  \n\n\n\n– \n\n\n\nHuman developmental cell atlas (HDCA) is the Swedish effort within the human cell atlas (HCA)\, one of the largest international scientific projects. The project aim is to create a comprehensive molecular atlas of human prenatal development at the molecular resolution using state-of-the-art multi-omic technologies such as single-cell RNA-seq\, Spatial Transcriptomics\, in situ sequencing in order to provide deeper insight into how variations and deviations contribute to health and disease. \n\n\n\nThe HDCA Seminar Series 2022 invites you to join us on a journey of early human organogenesis of several organs at the single-cell and spatial resolution. Seminars will be held at SciLifeLab Gamma building on Wednesdays at 14:00 or 15:00 and also via Zoom. After each seminar\, we will have up to 30 min round up discussions with the speaker on how you can contribute to the atlas! \n\n\n\nWarm Welcome!
URL:https://www.scilifelab.se/event/decoding-the-development-of-the-human-spinal-cord-by-multi-omics/
LOCATION:Gamma 2 Lunchroom\, SciLifeLab\, Tomtebodavägen 23\, Solna\, Sweden
CATEGORIES:Event
ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2022/04/hdca_logo.png
ORGANIZER;CN="The Human Developmental Cell Atlas":MAILTO:hdca-sweden@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220511T141500
DTEND;TZID=Europe/Stockholm:20220511T154500
DTSTAMP:20260408T004219
CREATED:20220502T110248Z
LAST-MODIFIED:20220504T075959Z
UID:10000599-1652278500-1652283900@www.scilifelab.se
SUMMARY:SciLifeLab COVID-19 seminar: Lilly Schwieler and Elham Rostami
DESCRIPTION:Topic: Neurological implication of COVID \n\n\n\nThe third SciLifeLab COVID-19 seminar this spring starts with Lilly Schwieler\, Associate Professor\, Physiology and Pharmacology\, Karolinska Institutet\,talking about Peripheral and central levels of kynurenine metabolites in COVID-19 patients. Elham Rostami\, Associate Professor\, Neurosurgery\, Uppsala university\,then continues the seminar with her talk on COVID19 and neurological complication. \n\n\n\nSchedule\n\n\n\n14:15-15:00Peripheral and central levels of kynurenine metabolites in COVID-19 patients.Lilly Schwieler\, Associate Professor\, Physiology and Pharmacology\, Karolinska Institutet15:00-15:45COVID19 and neurological complicationElham Rostami\, Associate Professor\, Neurosurgery\, Uppsala University\n\n\n\n\n\n\n\nRegistration is mandatory to get the Zoom link for the event  \n\n\n\n\nREGISTRATION\n\n\n\nBIOS & ABSTRACTS
URL:https://www.scilifelab.se/event/scilifelab-covid-19-seminar-lilly-schwieler-and-elham-rostami/
LOCATION:Online event via Zoom
CATEGORIES:Event
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220516T080000
DTEND;TZID=Europe/Stockholm:20220517T170000
DTSTAMP:20260408T004219
CREATED:20220309T093342Z
LAST-MODIFIED:20220512T143421Z
UID:10000548-1652688000-1652806800@www.scilifelab.se
SUMMARY:Planetary Biology Workshop
DESCRIPTION:EMBL-SciLifeLab workshop on the theme Planetary Biology \n\n\n\nThe purpose of the workshop is to enhance connectivity between researchers at both\, SciLifeLab and EMBL\, to identify new collaboration ideas\, and to promote joint technology and infrastructure resource development within Planetary Biology. \n\n\n\nThis is one of many workshops that will follow the conclusion of the MoU between SciLifeLab and EMBL in 2021. \n\n\n\nThe workshop is a hybrid event. Physical location is the EMBL Heidelberg campus\, where in-person attendance is limited. Allocation of spaces is on a first-come first-served basis.  \n\n\n\nPlease note: there are two separate registration links for on-site or virtual participation. In case you sign up for on-site participation but your availability changes\, please make sure to inform the responsible contacts. \n\n\n\nThe workshop will include talks on a broad set of themes including: \n\n\n\nBiodiversity Genomics & Reference Genome SequencingEcology & EvolutionBiogeochemistry & EcosystemsData-driven Planetary Biology\,\n\n\n\nAs well as invited keynote speakers and panel discussions. \n\n\n\nread more and sign up here\n\n\n\nDay 1\, Monday 16th May\, 2022 \n\n\n\n13:00Welcome and opening remarksEdith HeardDirector General of EMBLOlli KallioniemiDirector of SciLifeLab13:10Introduction and overview of Planetary BiologyDetlev ArendtPlanetary Biology Co-Chair\, Senior Scientist\, Group Leader\, EMBLOlga Vinnere Pettersson & Stefan BertilssonCo-Leads Planetary Biology Capability\, SciLifeLab13:30Session 1: Biodiversity Genomics & Reference Genome Sequencing (15 mins + 5 mins Q&A per speaker in each session)ModeratorPeter Harrison\, Genome Analysis Team Leader\, EMBL-EBISpeakersFergal Martin\, Vertebrate Annotation Coordinator\, EMBL-EBIKerstin Lindblad Toh (remote)\, Professor in Comparative Genomics\, Uppsala University\, Scientific Director of Vertebrate Genome Biology\, Broad InstituteDetlev Arendt\, Planetary Biology Co-Chair\, Senior Scientist\, Group Leader\, EMBLOve Nilsson\, Group Leader Control of Flowering Time and Tree Phenology\, Umeå Plant Science Center14:50 Coffee break15:10Session 2: Ecology and EvolutionModeratorOlga Vinnere Pettersson\, Co-Lead Planetary Biology Capability\, SciLifeLabSpeakersLove Dalén\, Professor of Evolutionary Genetics\, Swedish Museum of Natural History\, Research Leader at Center for Palaeogenetics\, StockholmMichael Dorrity\, Group Leader Structural and Computational Biology\, EMBLJames Sharpe (remote) \, Head of EMBL Barcelona\, Group Leader in Tissue Biology and Disease ModellingAnna Rosling\, Group Leader Ecology and Evolution in Soil Fungi\, Uppsala University16:30Keynote by Mark BlaxterWellcome Sanger Institute17:15Summary and Q&A\n\n\n\nDay 2\, Tuesday 17th May\, 2022 \n\n\n\n09:00Arrival and Coffee09:30Keynote by Martin PolzUniversity of Vienna10:20Session 3: Biogeochemistry & Ecosystems(15 mins + 5 mins Q&A per speaker in each session)ModeratorStefan Bertilsson\, Co-Lead Planetary Biology Capability\, SciLifeLabSpeakersMichael Zimmermann\, Group Leader in Structural and Computational Biology\, EMBLFlora Vincent\, Incoming Group Leader in Developmental Biology; Post Doctoral Fellow at Weizmann Institute of Science\, RehovotSara Hallin\, Professor at the Department of Forest Mycology and Plant Pathology\, Swedish University of Agricultural SciencesMark Dopson\, Professor at the Department of Biology and Environmental Science\, Linnaeus University11:40 Break12:40Session 4: Data-driven Planetary BiologyModeratorOliver Stegle\, Associate Group Leader in Genome Biology\, EMBLSpeakersTomas Roslin (remote)\, Professor at the Department of Ecology\, Swedish University of Agricultural SciencesPeer Bork\, Director of EMBL Heidelberg\, Group Leader in Structural and Computational Biology\, EMBLAnders Andersson\, Group Leader in Environmental Genomics\, Royal Institute of TechnologyAnna Kreshuk\, Group Leader in Cell Biology and Biophysics14:00Summary and Q&A14:15Coffee break14:45Panel Discussion 1: Technological Infrastructure Needs for PB ResearchModeratorStefan Bertilsson\, Co-Lead Planetary Biology Capability\, SciLifeLabPanelistsYannick Schwab\, Team Leader Volume Correlative Light and Electron Microscopy and Head of Electron Microscopy Core Facility\, EMBLTimo Zimmermann\, Team Leader Advanced Light Microscopy Technology Development and Service Provision\, EMBLLinda Sandblad\, Scientific Platform Director Cellular and Molecular Imaging\, Umeå University\, SciLifeLabOlga Vinnere Pettersson\, Project coordinator at Department of Immunology\, Genetics and Pathology\, Uppsala University; Co-Lead Planetary Biology Capability\, SciLifeLabAnnika Johansson\, Head of Swedish Metabolomics Centre\, Umeå University\, SciLifeLab16:00Short break16:10Panel Discussion 2: Data Collection in PB ResearchModeratorOlga Vinnere Pettersson\, Co-Lead Planetary Biology Capability\, SciLifeLabPanelistsRainer Pepperkok\, Director of Scientific Core Facilities and Scientific Services\, Team Leader Membrane traffic and Organelle Biogenesis\, EMBLStefan Bertilsson\, Professor in Functional Ecology of Freshwaters\, Swedish University of Agricultural Sciences; Director of the Swedish Infrastructure for Ecosystem Science (SITES); Co-Lead Planetary Biology Capability\, SciLifeLabFredrik Ronqvist\, Professor in the Department of Bioinformatics and Genetics\, Swedish Museum of Natural History; Swedish Biodiversity Data Infrastructure (SBDI)16:40Panel Discussion 3: Data Management and Processing in PB ResearchModeratorFergal Martin\, Eukaryotic Annotation Team Leader\, EMBL-EBIPanelistsGuy Cochrane (remote)\, Team Leader Data Coordination and Archiving\, EMBL-EBIBlokeshwaran Manoharan\, Expert in Metagenomics; National Bioinformatics Infrastructure Sweden (NBIS)Johan Rung\, Head of Data Center\, SciLifeLab17:00Conclusion and Closing Remarks\n\n\n\n \n\n\n\n \n\n\n\n \n\n\n\n \n\n\n\n \n\n\n\nScientific committee SciLifeLab\n\n\n\nStefan Bertilsson\, SLUOlga Vinnere Pettersson\, Uppsala University
URL:https://www.scilifelab.se/event/planetary-biology-workshop/
LOCATION:EMBL Heidelberg\, Meyerhofstraße 1\, Heidelberg\, Germany
CATEGORIES:Event
ATTACH;FMTTYPE=image/jpeg:https://www.scilifelab.se/wp-content/uploads/2021/12/AdobeStock_421805105_Planetary_biology_WP.jpg
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BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220516T091500
DTEND;TZID=Europe/Stockholm:20220516T163000
DTSTAMP:20260408T004219
CREATED:20220321T154432Z
LAST-MODIFIED:20220323T125900Z
UID:10000564-1652692500-1652718600@www.scilifelab.se
SUMMARY:AI / Data-driven life science
DESCRIPTION:Life science research is becoming increasingly dependent on data\, and never before has so much data been generated today. The amount and complexity increase exponentially\, and when this data becomes open to researchers around the world\, more scientific discoveries are made possible. The rapid technological development in life sciences\, combined with innovations in computing and AI\, will play an increasingly important role in research and development and affect virtually all areas of medicine and science. \n\n\n\nDuring this day\, you will meet prominent international and local researchers\, take part in current research\, and discuss open data\, AI\, ethics\, and visualization related to life science.  \n\n\n\nContacts: Carolina Wählby and Bent Persson. \n\n\n\nVenue: Ångströmslaboratoriet\, Lägerhyddsvägen 1\, Uppsala \n\n\n\nRegistration opens at the end of March.  \n\n\n\nProgram and registration will be published here! \n\n\n\n\n\n\n\nThe event is part of Uppsala University’s multidisciplinary theme week in technology and science from May 16 to 20\, at the Ångström Laboratory. During the week\, you will be able to take part in current research in AI / Data-driven life science\, the universe and mathematical physics\, materials\, energy\, and climate change.
URL:https://www.scilifelab.se/event/ai-data-driven-life-science/
LOCATION:Ångströmlaboratoriet\, Lägerhyddsvägen 1\, Uppsala\, Sweden
CATEGORIES:Event
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BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220516T171500
DTEND;TZID=Europe/Stockholm:20220516T181500
DTSTAMP:20260408T004219
CREATED:20220422T112304Z
LAST-MODIFIED:20220505T130333Z
UID:10000591-1652721300-1652724900@www.scilifelab.se
SUMMARY:The Svedberg seminar: Simon Elsässer
DESCRIPTION:Register and get the link here\n\n\n\n\n\nSimon Elsässer is  Associate Professor at Karolinska Institutet\, Department of Medical Biochemistry and Biophysics. He has studied at University of Tübingen and Harvard University\, and received his Ph.D. from The Rockefeller University in 2012. He has performed postdoctoral research at MRC Laboratory of Molecular Biology and was recruited to Karolinska Institutet as a SciLifeLab Fellow in 2015. His research combines synthetic biology methods to probe and manipulate proteins in the living cell with quantitative ‘omics readouts\, focusing on stem cells\, gene expression regulation and epigenomics. \n\n\n\nTitle of the seminar: Exploring the dynamics of the pluripotent epigenome and lineage choice in development\n\n\n\n \n\n\n\nShort Abstract: \n\n\n\nThe first lineage choice made in human embryo development separates trophectoderm from the inner cell mass\, which proceeds to form the pluripotent epiblast and primitive endoderm. We discovered that Polycomb repressive complex 2 (PRC2) maintains naïve pluripotency and restricts an intrinsic capacity of pre-implantation pluripotent stem cells to give rise to extraembryonic lineages. Through quantitative ChIP-seq and single-cell transcriptomics\, we demonstrate that PRC2-mediated repression provides a highly adaptive mechanism to restrict lineage potential during early human development.Webpage: http://www.elsaesserlab.org
URL:https://www.scilifelab.se/event/simon-elsasser/
LOCATION:Online event via Zoom
CATEGORIES:Event
ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2022/04/Picture1-The-Svedberg-edited.png
ORGANIZER;CN="The Svedberg Seminar Series":MAILTO:thesvedberg@scilifelab.uu.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220518T090000
DTEND;TZID=Europe/Stockholm:20220519T130000
DTSTAMP:20260408T004219
CREATED:20220408T121642Z
LAST-MODIFIED:20220408T130957Z
UID:10000578-1652864400-1652965200@www.scilifelab.se
SUMMARY:Handling Pandemic Omics Data in the Nordics
DESCRIPTION:Dates: 18 & 19th May (9:00-13:00)\n\n\n\nLocation: online via Zoom\n\n\n\nThe current COVID-19 pandemic has understandably received considerable attention worldwide over the last few years. As it spread across the globe\, the pandemic posed significant challenges for society\, governmental bodies\, healthcare systems\, and research communities. Unprecedented efforts were necessary to  generate\, handle\, and report the sheer amount of complex data required to be able to understand how SARS-CoV-2 was spreading\, and develop efficient policies to fight the pandemic. \n\n\n\nSciLifeLab Data Centre\, ELIXIR Norway and ELIXIR Estonia have organised an online event exploring how Nordic countries handled omics data related to the SARS-CoV-2 pandemic. We invite bioinformaticians\, data stewards\, research scientists\, and anyone else interested in this topic to attend. We will focus in particular on how sequencing efforts were coordinated\, how data was managed and shared\, and how data was used and communicated to different groups. We will also discuss the importance of the FAIR principles in pandemic data management\, and which tools and pipelines facilitated efforts. We hope that this will shed light on best practices that could be adopted across the Nordics for future pandemics\, and how we might best prepare for them. We also hope to identify key resources that have wider applicability and can be reused further. \n\n\n\nThe programme is available at:  \n\n\n\nhttps://nordic-compbio.iscbsc.org/omics-data. \n\n\n\nFor any queries about the meeting\, please email nazeefaf@uio.no \n\n\n\n \n\n\n\nRegister Here
URL:https://www.scilifelab.se/event/handling-pandemic-omics-data-in-the-nordics/
LOCATION:Online event via Zoom
CATEGORIES:Event
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