SciLifeLab

Beta building Walkabout
2025-05-20 13:00 - 14:30 (Europe/Stockholm) | Delta, Campus Solna, Tomtebodavägen 23a, Solna
SciLifeLab and Campus Solna Leadership, and Akademiska hus invites you to a walkabout in the Beta building on May 20. Everyone is welcome to experience the “before” of the exciting and ongoing project to incorporate the Beta Building into SciLifeLab, creating what can be called SciLifeLab Campus Solna v 3.0.

By consolidating the Beta building into our campus, 50% more space is gained, a requisite to meet future challenges and to continue as an internationally recognised and impactful research facility dedicated to deciphering life processes at the molecular level.

Program

13.00Gathering and Coffee13.10Welcoming words, Per Ljungdahl13.15Future Perspectives, Jan Ellenberg13.20Akademiska Hus gives information13.30The doors of Beta will open14.30The doors of Beta will close

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[Spotlight seminar] Investigating the regulatory impact of rare non-coding somatic mutations in cancer
2025-05-20 15:15 - 16:15 | Gamma 2 Lunchroom, SciLifeLab, Tomtebodavägen 23, Solna, Sweden
Spotlight seminar series proudly presents Lude Franke, Professor of functional genomics, University Medical Centre Groningen, The Netherlands

Abstract

Both germline and somatic variation play an important role in cancer. In the past years a lot of progress has been made in the identification of germline variants that confer cancer risk, and a large number of somatic driver mutations have now been found. Here, we set out to study the role of non-coding somatic mutations in cancer and studied whole-genome sequence data of 25,000 cancer patients where we employed sequence-based models to identify hundreds of non-coding regions that are enriched for activating or repressing mutations. We subsequently studied how these non-coding somatic mutations cause disease and observed these mutations are related to known somatic driver genes ad germline risk variants through when employing gene regulatory networks. I will discuss how such gene regulatory networks can be reconstructed using trans-eQTL data in 43,000 invidiuals.

Biography

Lude Franke develops and applies computational methods to understand the downstream molecular consequences of genetic risk factors. We studied the effect of somatic copy number alterations on gene expression levels (Fehrmann et al, Nature Genetics 2015) and studied the effect of genetic single-nucleotide polymorphism on methylation (Bonder et al, Nature Genetics 2017) and gene expression (i.e. expression quantitative trait loci), both in blood using bulk data (Zhernakova et al, Nature Genetics 2017 and Vosa et al, Nature Genetics 2021) and single-cell data (Van der Wijst, Nature Genetics 2018). Recently, we did this in brain (De Klein, Nature Genetics 2023). We lead the eQTLGen and single-cell eQTL consortia (see eQTLGen.org), where we use federated meta-analyses approaches to generate comprehensive maps how genetic variation is exerting cell-type and context-specific effects on gene expression, with the aim to help identify and validate drug targets.

Meet the Experts: Drug Development Drop-In with OligoNova/SciLifeLab DDD
2025-05-21 09:00 - 15:00 | SciLifeLab Gothenburg Office Hub, Medicinaregatan 3, Gothenburg, 41390, Sweden
Accelerate Your Drug Discovery Research with OligoNova & SciLifeLab DDD

OligoNova’s mission is to transform cutting-edge academic research in therapeutic oligonucleotides into innovative medicines that address unmet medical needs.

We provide:

Industry-standard infrastructure

A dedicated team of drug discovery experts

Strategic guidance to help you advance your asset toward preclinical proof of concept molecule, supported by a robust, validated data package for potential further development and commercialization.

What Can You Explore or Get Support With?

At this drop-in event, you can learn more about:

Available support for your research through OligoNova and SciLifeLab DDD

Drug development programs and how to get involved

Service projects – including assays, instrumentation, and synthesis

Consultation meetings – from early ideas to strategic planning

Application processes – for various types of drug development support

Master’s thesis opportunities

General questions about drug development

Accessing and using OligoNova’s infrastructure

Whether you’re curious, ready to apply, or just want to chat about your research – you’re most welcome to stop by!

More information can be also be found at the webpages of OligoNova, OligoNova Hub and the SciLifeLab DDD platform.

Warm regards,The OligoNova Team

From Algorithms to the Clinic: How we are bringing digital technologies into clinical practice
2025-05-23 09:00 - 10:00 | Online event via Zoom
Marco Perez, an Associate Professor at Stanford University

Biography

Dr. Marco Perez, an Associate Professor at Stanford University, focuses on understanding the causes of cardiovascular disease and the role of digital health technologies in improving cardiovascular health. He has been involved in landmark studies, including the Women’s Health Initiative and the Apple Heart Study, which validated smartwatch detection of atrial fibrillation. Currently, he serves as the Principal Investigator of the Central Coordinating Centre for the REACT-AF clinical trial, which explores a “pill-in-the-pocket” anticoagulation approach for atrial fibrillation using smartwatches.

Abstract

The availability of digital tools in medicine is expanding rapidly. More than ever before, we have access to large datasets and machine learning tools that can help us decipher this data. In addition, our patients are being monitored nearly continuously with consumer devices that are connected and available to us as a tool for research and health care delivery. We will discuss our experience with how we are using these tools in clinical trials, what we can learn from these studies and where we need to go next to make the most significant impact.

About Clinical Talks

Clinical Talks returns with a new season!

After seven successful seasons and over seventy dedicated speakers, we are excited to continue showcasing the contributions of our diverse clinical, academic, and industry life science community. This season will feature ten insightful talks following our well-established format.

The overarching theme is “How to Achieve Feasible Implementation.” Sessions will be heldmonthly on Fridays from 09:00 a.m. to 09:30 a.m. via Zoom, with occasional exceptions. Each talk will be followed by an engaging Q&A session, moderated by standing host Rikard Fred and a guest moderator with subject matter expertise to enrich the discussion.

In today’s rapidly evolving post-pandemic landscape, exploring how academic, clinical, and industry research, combined with technological advancements, can drive practical and sustainable solutions is crucial. Join us for an opportunity to gain fresh insights, expand your knowledge, and connect with experts shaping the future of Life Sciences!

Clinical Talks are organised by SciLifeLab.

Register Here

“From Algorithms to the Clinic: How we are bringing digital technologies into clinical practice”

Seqera AI: How we're using LLMs and Agents with Nextflow code.
2025-05-23 10:00 - 11:00 | Online event via Zoom
Phil Ewels, Seqera

NBIS and SciLifeLab Data Centre arrange an open SciLifeLab AI Seminar Series aimed at knowledge-sharing about Artificial Intelligence and applications in the Life Science community. The seminar series is open to everyone. The seminar is run over Zoom on the third Friday of the month during academic terms, typically between 10 and 11 am, with approx. 45 min presentation and 15 min discussion.

Abstract

​LLMs are fast becoming an indispensable tool for anyone writing software. But how well do they cope with Nextflow pipelines? Hear how Seqera is building a suite of AI tools that can kickstart Nextflow developer experience and integrate deeply with bioinformaticians’ tool chains. Learn how we’re going beyond simple chat interfaces, with agentic tooling that can fast-track edits without sacrificing accuracy and reproducibility.

EATRIS Sweden in the Spotlight Symposium
2025-05-26 08:30 - 16:00 | Life City, Solnavägen 3H, Stockholm, 113 63
AI in healthcare – opportunities, challenges and ethical considerations

The “EATRIS Spotlight Programme” highlights the scientific excellence and capacities of its member countries while enhancing visibility at both a national and European level. EATRIS Sweden’s term as the spotlight country will come to an end in May 2025, and the EATRIS Sweden team is inviting all EATRIS members to join them at a closing symposium titled “AI in healthcare – opportunities, challenges and ethical considerations”.

To register, visit the EATRIS webpage.

Preliminary Programme

8:30 – 9:00Registration9:00Welcome – Pontus Aspenström, National Director EATRIS SwedenAnton Ussi, Operations & Finance Director, EATRIS C&S

Session I

9:10Ola Spjuth, Uppsala University, SciLifeLab – SciLifeLab and AI: Perspectives and strategies9:35Sven Nelander, Uppsala University – AI strategies to combat brain tumor progression10:00Claes Lundström, Linköping University – The interplay between AI and human expertise in diagnostic imaging10:25 – 11:00Coffee

Session II

11:00Mattias Rantalainen, Karolinska Institutet – TBD11:25Julián Prieto and Carolina de la Pinta, IRYCIS, Spain – Trustworthy predictive systems in translational medicine11:50Stella Riad, RISE – Beyond the hype: Practical AI applications and challenges in healthcare12:15 – 13:15Lunch

Session III

13:15Johan Hartman, Stratipath, Karolinska Institutet – Implementation of AI-based precision pathology in routine healthcare13:40Jason Tucker, Institute for Futures Studies & AI Policy Lab @Umeå University – Why we should care about the global politics behind AI in healthcare14:05Santa Slokenberga, Uppsala University – Legal Preconditions for AI in Healthcare: §Navigating Compliance and Operalization14:30 – 15:00Coffee

Session IV

15:00Jessica Nihlén Fahlkvist, Uppsala University – AI Ethics and Medical Research15:25Luis Mendes, EATRIS Digital Transformation Expert Group – AI and Diabetic Retinopathy: Challenges and Opportunities for Better Diabetes Care15:50TBA16:15Concluding remarks16:30End of meeting

The future of Open Science in Sweden
2025-05-27 10:15 - 12:00 | Online event via Zoom
Sweden has been at the forefront of the Open Science movement, with national policies promoting open access to research publications, FAIR data principles, and new approaches to research assessment. However, challenges remain in fully integrating Open Science into funding structures, career evaluations, and institutional practices.

Join us for an insightful roundtable on the future of Open Science implementation in Sweden! Richard Williams, a postdoctoral researcher in the philosophy of Open Science at the Technical University of Munich, will open the discussion with a critical examination of the Open Science movement. Following this, Angeliki Adamaki – Lund University Open Science-champion and co-founder of Open Science Community Lund -, Sanna Isabel Ulfsparre – analyst at Vetenskapsrådet specializing in Open Science and research data -, and Stefan Ekman – senior advisor at the Swedish National Data Service (SND) – will explore key challenges, opportunities, and next steps for Open Science in Sweden.

Presenters:

Richard Williams, Technical University of Munich

Angeliki Adamaki, Lund University

Sanna Isabel Ulfsparre, Vetenskapsrådet

Stefan Ekman, Swedish National Data Service

Discussion leaders:

Ineke Luijten, SciLifeLab Training Hub

Elin Kronander, National Bioinformatics Infrastructure Sweden

Don’t miss the opportunity to gain fresh insights and contribute to the conversation!

Register Here

Nobel symposium public lectures
2025-05-30 10:00 - 12:30 | Aula Magna, Frescativägen 6, Stockholm, 114 18 Stockholm, Sweden
Welcome to attend the Nobel Symposium Public Lectures. Free entrance, no registration required. Read more about the prominent Speakers below.

”Can we bring back the woolly mammoth?”

Prof. Beth Shapiro, Colossal Bioscience, USA

”The taming of the horse”

Prof. Ludovic Orlando, Centre for Anthropobiology and Genomics of Toulouse, France

Date: May 30, 2025

Time: 10:00-12:30

Venue: Aula Magna, Stockholm University, Frescativägen 6, Stockholm

Organizers: Centre for Palaeogenetics, SciLifeLab Ancient DNA unit, Uppsala University Human Evolution research program

Beth Shapiro, Ph.D
Beth Shapiro is an evolutionary biologist who specializes in the genetics of ice age animals and plants. As Professor of Ecology and Evolutionary Biology at UC Santa Cruz and HHMI Investigator, Beth uses DNA recovered from bones and other remains to study how species evolved through time and how human activities have affected and continue to affect this dynamic process. Her work focuses on organisms ranging from influenza to mammoths, asking questions about domestication, admixture, speciation, and pathogen evolution. Her current work develops techniques to recover increasingly trace amounts of DNA such as from environmental and forensic samples. A 2009 MacArthur Fellow, Beth is also an award-winning popular science author and communicator who uses her research as a platform to explore the potential of genomic technologies for conservation and medicine.

Prof. Ludovic Orlando
Ludovic is a former student from the Ecole Normale Supérieure of Lyon (1996-2000), one of the top-5 French universities. First trained as a molecular biologist, he soon became interested in applying computational techniques to DNA sequence data. He graduated in molecular genetics from the Univ of Lyon, France in 2003, twenty years after the first ancient DNA molecule was sequenced. He was appointed as a permanent Associate Professor at ENS Lyon, where he lectured and performed research between 2005 and 2010. He started his own research group in 2010 at the Centre for GeoGenetics, Univ of Copenhagen, Denmark, where he was appointed as a full Professor in ‘Molecular Archaeology’ until 2020. He became a CNRS research director in 2016. He founded the Centre for Anthropobiology and Genomics (CAGT) in 2020, and as acted as its director since. He is also the head of the AnimalFarm CNRS International Research Programme, grouping together 4 leading ancient DNA labs at Univ of Oxfort, Trinity College Dublin, and LMU Munich, all focused on the reconstruction of the domestication history of animal domestic species.

Amongst his early career achievements feature (1) the sequencing of the first Middle Pleistocene genome, (2) the characterization of the first ancient epigenome, and (3) the identification of the horse and donkey domestication homelands.

He has been part of several organizing and scientific boards of international meetings, including for the Society of Molecular Biology and Evolution, the International Symposium on Biomolecular Archaeology, the International Union for Quaternary Research and the International Union of the Protohistoric and Prehistoric Sciences. He has been an Academic Editor and/or Editor-in-Chief for multiple scientific journals, including PLoS One, Scientific Reports, Peer J and STAR. He published 200+ scientific research articles and several books. He took part of several national research committees, including for the French National Research Agency (ANR) (2012 and 2013), the ‘Institut Universitaire de France’ (2015 and 2016), INRAE Genomics (2020-) and the Scientific Advisory Board of France Génomique (2021-). His research has received multiple national and international funding, including from multiple Marie-Curie programmes, and two prestigious grants from the European Research Council (CoG PEGASUS, and SyG Horsepower). He was awarded the CNRS Silver Medal in 2023 « for the originality, quality, and importance of (his) work, which is recognised at national and international level.

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Nano-electrokinetic transcriptomics empowers the phenotyping of single cells
2025-05-30 14:00 - 17:00 | Air&Fire, SciLifeLab Stockholm, Tomtebodavägen 23A, Solna, Sweden
Seminar with Prof. Hirofumi Shintaku, Kyoto University, Japan

Host: Ian Hoffecker, SciLifeLab

registration

You can also follow the meeting via Zoom.

Abstract

Nanopore electroporation uses nanoscale structures to create focused electric fields, which form pores in lipid bilayers with low invasiveness. We here discuss the biophysics of the pore formation that depends on the cell surface tension and introduce an approach that leverages nanopore electroporation and single-cell RNA-sequencing to parallelly profile cell surface tension and gene expression, electroporation-based lipid-bilayer assay for cell surface tension (ELASTomics). We show that ELASTomics dissects the heterogeneity in cellular mechanics and uncovers the regulatory mechanism in cancer malignancy, cell differentiation, and cellular senescence.

Biography

Dr. Hirofumi Shintaku is a Professor at the Institute for Life and Medical Sciences (LiMe), Kyoto University.

He studied Mechanical Engineering at Kyoto University in Japan, receiving his undergraduate, master’s, and Ph.D. degrees in 2002, 2004, and 2006, respectively. From 2006-2012, he worked as a Research Associate in the Department of Mechanical Science and Bioengineering at Osaka University in Japan. From 2012 to 2018, he worked as an Assistant Professor in the Department of Micro Engineering at Kyoto University. From 2012 to 2015, he was a visiting scholar at Stanford University in the United States and collaborated with Professor Juan G. Santiago. From 2018 to 2025, he worked as a RIKEN Hakubi Team leader at RIKEN, where he initiated his own research group and has pioneered single-cell RNA-sequencing approaches, SINC-seq (Abdelmoez et al. Genome Biol 2018, Oguchi et al. Sci Adv 2021), ELASTomics (Shiomi et al. Nat Commun 2024), and live embryonic transcriptomics (Torii et al. under review). Since 2023, he has been directing the Nano Bioengineering Laboratory at LiMe, Kyoto University.

He was awarded the Best Paper Award from JSAEM (2006), the IIP Division Award for Young Engineer from JSME(’09), JSME Young Engineers Award (2010), Osaka University Achievement Award (2011), Certificate of Merit for Micro-Nano Science and Technology Division of JSME (’14), the Micro-Nano Engineering Excellent Paper Certificate of Merit (2022), Nakatani Encouragement Award (2025), RIKEN Biho Award (2025).

His current research activities include developing microfluidic systems for single-cell analyses and measurement techniques of fluid dynamics in nano/micro-confined spaces.

[The Svedberg seminar] - The world of viruses and its evolution through the lens of metagenomics and metatranscriptomics
2025-06-02 15:15 - 16:15 | BMC Room C8:301, Husargatan 3, Uppsala, Sweden
Eugene V. KooninHead of Evolutionary Genomics Group at the National Center for Biotechnology Information (NCBI) at the NIH, USA

Bio

Eugene V. Koonin is an NIH Distinguished Investigator, the leader of the Evolutionary Genomics Group at the National Center for Biotechnology Information (NCBI) at the NIH. He graduated from Moscow State University in 1978 and was awarded a PhD in Virology by the same university in 1983. He joined the NIH in 1991 and became a Senior Investigator in 1996 and a Distinguished Investigator in 2019. Dr. Koonin’s research focuses on genome evolution, especially in microbes and viruses, host-parasite coevolution, and more specifically, functions and evolution of antivirus defense systems, in particular, CRISPR-Cas. Dr. Koonin is the author of the concept and implementation of Clusters of Orthologous Genes which are central to comparative and evolutionary genomics. He also develops mathematical models of various evolutionary process and works on general theory of evolution based on physical principles. Dr. Koonin has published about 1100 research and review papers, many in premier scientific journals, that have been cited more than 265,000 times. He is also the author of the 2011 book “The Logic of Chance” which outlines a new synthesis of Evolutionary Biology. His h-index is 246 according to Google Scholar. Dr Koonin is a member of the National Academy of Sciences of the USA, National Academy of Medicine of the USA, American Academy of Arts and Sciences, and American Academy of Microbiology, a Foreign Associate of the European Molecular Biology Organization and Academia Europea, and a Doctor Honoris Causa of Universite Aix-Marseille, Wageningen University, Weizmann Institute of Science and University of Haifa.

The world of viruses and its evolution through the lens of metagenomics and metatranscriptomics

Viruses and virus-like mobile genetic elements are ubiquitous parasites or symbionts of all cellular life forms and the most abundant biological entities on earth. The recent, unprecedented advances of comparative genomics, metagenomics and metatranscriptomics have led to the discovery of diverse novel groups of viruses and a rapid expansion of the chartered region of the virosphere. These discoveries provide for a vastly improved understanding of the evolutionary relationships within the virosphere. Arguably, we are approaching the point when the global architecture of the virus world can be outlined in its entirety, and the key evolutionary events in each of its domains can be reconstructed. I will present such an outline of the global organization of the virosphere and the corresponding megataxonomy, including 7 evolutionarily coherent virus realms, that has been recently approved by the International Committee on Taxonomy of Viruses, as well as additional candidate major taxa including new realms. The expansion of the prokaryotic virosphere that now includes many groups of viruses, particularly, those with RNA genomes, previously thought to be eukaryote-specific, will be emphasized. I will further discuss the position of viruses within the wider space of replicators and the recent dramatic expansion of the “alternative virosphere” that includes viroids and diverse viroid-like viruses that seem to have evolved on multiple, independent occasions.

Host: Peter Bozhkov peter.bozhkov@slu.se

Fragmentomics as a Pancancer Biomarker in Liquid Biopsies
2025-06-05 11:00 - 12:00 | Online event via Zoom
Clinical Genomics Webinar Series

Clinical Genomics Örebro is hosting this webinar as part of the webinar series by the Clinical Genomics Platform

Development of new biomarkers to detect cancer in liquid biopsies in patients with nonspecific symptoms of cancer

join Teams webinar

The webinar will cover how we generally work with the development of new biomarkers to detect cancer using liquid biopsies in patients with nonspecific symptoms of cancer. More specifically, the concept of fragmentomics will be presented and preliminary data from an ongoing study.

Everyone is welcome so feel free to spread the details with anyone who may be interested. Hope to see you there!

Host: Gisela Helenius, Platform Scientific Director at Clinical Genomics Örebro

Invited speaker: Alvida Qvick och Mårten Lindqvist, Clinical Genomics Örebro

[Spotlight seminar] Applying innovate genomic approaches to the detection and control of infectious diseases
2025-06-09 15:00 - 16:00 | Air&Fire, SciLifeLab Stockholm, Tomtebodavägen 23A, Solna, Sweden
Professor Deborah Williamson. University of St. Andrews

Biography

Professor Williamson is Dean of the Faculty of Medicine and Head of the School of Medicine. She has held strategic leadership roles in academia and public health agencies across Australia, New Zealand, and the UK. She is a clinician-scientist with a global network of collaborators and over 300 journal publications. Her work has attracted significant research funding and has been recognised with awards such as the L’Oreal-UNESCO Women in Science Fellowship.

Her research focuses on the development and application of innovative technologies, particularly genomics, to address infectious diseases. Professor Williamson has a strong clinical and public health background in microbiology and virology and remains actively engaged in clinical and public health service.

Abstract

Advances in genomics and diagnostics are transforming how we detect, monitor, and respond to infectious diseases. This talk highlights emerging tools and approaches that combine rapid diagnostic techniques with genomic insights to support real-time public health action. It explores the potential of new technologies to enhance sensitivity, specificity, and accessibility of testing, and examines how these innovations can be applied across a range of settings and pathogens. Drawing on global collaborations and practical examples, the presentation emphasises the value of integrated strategies in strengthening infectious disease control and preparedness worldwide.

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[The Svedberg seminar] - The evolution of codon usage bias in humans: the unwanted transcript hypothesis
2025-06-09 15:15 - 16:15 | BMC Room C8:301, Husargatan 3, Uppsala, Sweden
Laurence HurstProfessor of Evolutionary Genetics at The Milner Centre For Evolution

University of Bath UK

Biography

Laurence Hurst is Professor of Evolutionary Genetics at The Milner Centre For Evolution, University of Bath UK, of which he was the founding Director. He works on fundamental problems in the evolution of genetic systems often with application to medicine. He was elected a Fellow of the Academy of Medical Sciences and a Fellow of the Royal Society (FRS) in 2015. He was a recipient of the Humboldt Prize (2024), the VC Research Medal (2015), the Scientific Medal of the Zoological Society of London (2003), the Darwin Award of the BA (2000) and was elected a member of European Molecular Biology Organization (EMBO) in 2004. He was awarded The Genetics Society Medal in 2010 and was its President from 2018-2021. Aside from being on the editorial board of multiple journals, he is on the Scientific Advisory Board of ExpressionEdits and the Advisory Board of PlosB.

The evolution of codon usage bias in humans: the unwanted transcript hypothesis

Although translational selection to favour codons matching the most abundant tRNAs is not readily observed in humans, nonetheless ~20% of synonymous mutations are under selection. We hypothesize that much of this reflects protection against unwanted RNAs – spurious transcripts, mis-spliced forms or RNAs derived from transposable elements or viruses. We propose that selection on synonymous sites functions to reduce the rate of creation of unwanted transcripts and to filter if created. Specifically, high-GC content is both particular to functional native mRNAs and used to recognize transcripts as native. In support of this hypothesis, transcription, nuclear export, liquid phase condensation and RNA degradation promote GC-rich transcripts and suppress AU ones. With such ‘traps’, the codon usage of native genes has, in turn, evolved to avoid such suppression. That parallel filters also affect the endosomal import of RNAs provides common design rules for both transgenes and RNA vaccines.

Host: Matthew Christmas matthew.christmas@imbim.uu.se

Global impact of sharing Open Educational Materials: Examples from Sweden and Africa
2025-06-10 11:00 - 12:00 | Online event via Zoom
Have you created a presentation or taken a course in the past year? If so, you’ve likely already interacted with Open Educational Resources (OER)—materials that are free to use, adapt, and share. This seminar at SciLifeLab is for anyone who creates training and wants to make their content FAIR (Findable, Accessible, Interoperable, Reusable), as well as for students and lifelong learners looking to enhance their skills using openly available resources. We’ll explore the FAIR-by-design methodology for training materials, where to find high-quality content in repositories, and case studies of research output reuse in the creation of training events and resources from Africa— highlighting why sharing matters and who benefits beyond the original creators. Join us to discover how open education can be a win for both you and the global learning community.

This event is organized by SciLifeLab Data Centre, and NBIS.

Presenters:

Anelda van der Walt – TalarifyAnelda’s background in Bioinformatics provided the foundation for her work in open science. After working across industry, academia, and the public sector, she started a consulting and training company, Talarify, in South Africa. Her work focuses on open science, reproducible research, and interdisciplinary collaborations.

Ineke Luijten – SciLifeLab Training Hub With a background in molecular bioscience, Ineke currently develops and delivers cross-disciplinary training modules on Open Science and FAIR principles. She is a member of the Open Science community and a strong advocate for Open Science and FAIR.

More info

This event is part of the SciLifeLab Data Management seminar series, an event series by the SciLifeLab Data Centre and NBIS joint Data Management team.

The goal of the events in this seminar series is to provide interesting interactive seminars around topics related to Research Data Management and Open Science in general, and to foster discussions around best practices.

The events are open to everyone working at or affiliated with a Swedish research institute or university. We welcome all researchers, educational professionals, staff, RDM professionals, and others with an interest in life sciences, from all university levels. The events are informal and inclusive, so feel welcome to join and participate in our interesting discussions!

The events will be recorded and published openly after the seminars on the SciLifeLab YouTube channel.

Link to the recording on will follow after the presentation.

Link to the presentation slides will follow after the presentation.More information about SciLifeLab Data Centre and NBIS joint Data Management seminar series: https://www.scilifelab.se/data/scilifelab-data-management-seminar-series/

For more information or inquiries, please contact: data-management@scilifelab.se

Towards Quantum Advantage by 2026: IBM’s Vision for Life Sciences
2025-06-12 10:00 - 12:00 | Air&Fire, SciLifeLab Stockholm, Tomtebodavägen 23A, Solna, Sweden
Join us for a special guest talk with Dr. Gopal Karemore, as he outlines how quantum computing is unlocking new possibilities in biomedical research and reshaping the future of healthcare innovation.With a background in data science and nearly a decade at Novo Nordisk, Gopal now leads IBM Quantum’s global strategy for applying quantum technologies to challenges in drug discovery, biomolecular simulation, and precision medicine to help enterprise clients. His work includes advancing methods like Sample-Based Quantum Diagonalization (SBQD) and contributing in collaborations with organizations such as Moderna and Cleveland Clinic. In this session, Gopal will:

Introduce IBM’s roadmap to achieving quantum advantage by 2026

Discuss how quantum technologies intersect with key challenges in healthcare and life sciences

Share real-world use cases from IBM’s work in quantum simulation, quantum optimization, quantum machine learning and collaborative biomedical ecosystems

Explore how researchers, scientists, and Nordic startups can engage with IBM — whether through programs like the Quantum Accelerator or other pathways — to gain access to quantum technologies already available today.

This talk is ideal for scientists, clinicians, data specialists, and innovators interested in the next frontier of life science computation — and how Sweden’s research community can help shape it.

Place: SciLife Lab, Tomtebodavägen 23, Solna. Conference room “Air&Fire”.

Agenda: 10.15 – 10:30 – Doors open & welcome10:30 – 11:30 – Presentation by Gopal Karemore followed by Q&A11:30 –12:00 – Lunch & networking mingleAbout the Speaker:Dr. Gopal Karemore is the Global Quantum Lead for Healthcare and Life Sciences at IBM Research, based at the T.J. Watson Research Centre in New York. He leads efforts to drive the adoption of quantum computing in life sciences and healthcare, working with IBM teams and external partners to deliver high-impact solutions. With over 14 years of experience in pharmaceutical research, Dr. Karemore brings deep expertise in data science, machine learning, and quantum computing. He holds a Ph.D. in Computer Science from the University of Copenhagen and has contributed to shaping innovation and business development across pharmaceutical R&D. Prior to joining IBM, he held research and leadership roles at Novo Nordisk, Spanish National Centre for Cardiovascular Research, Danish Stem Cell Centre, Centre for Protein Research, Fraunhofer Institute, and Penn Medicine.

Exploring the Protein Universe via Highly Accurate Structural Predictions
2025-06-12 15:00 - 16:00 | Milkyway SciLifeLab Solna, Tomtebodavägen 23, Solna
Speaker

Martin Steinegger, Seoul National University

Abstract

Understanding relationships and functions of proteins at a global scale is key to unlocking newbiological insights. Through next-generation structure predictors like AlphaFold2 and ESMfold,we now have access to an unprecedented volume of protein structures, providing a crucialfoundation to address this challenge. In this talk, I will present how our computationalmethods ColabFold, MMseqs2, and Foldseek together allow extraction of biological insightsfrom protein sequences and structures at nearly billion-scale. Additionally, I will demonstratehow protein language models combined with sparse experimental data can guide andprioritize experimental efforts, enabling efficient iterative “lab-in-the-loop” research.Together, these tools democratize computational analysis and significantly acceleratediscoveries in protein biology.

Stora digitala europeiska satsningar för bättre hälsa, sjukvård, forskning och innovation
2025-06-25 13:00 - 14:00 | D-huset, Campus Gotland, Kaserngatan 1, Visby, Sweden
Nu pågår stora europeiska digitala satsningar inom biomedicin för bättre hälso- och sjukvård, forskning och innovation. Sverige är ledande i flera av dessa, såsom Genomic Data Infrastructure (GDI) för sekvensdata, Bigpicture för digital patologi och EUCAIM för bilddata inom cancer.

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Alla projekten leder till förbättrad hälso- och sjukvård, inklusive utveckling av precisionsmedicin samtidigt som de möjliggör ny avancerad forskning och förbättrad innovation. Genomic Data Infrastructure (GDI) ger tillgång till miljontals DNA-sekvenser för forskning, sjukvård och innovation, Bigpicture skapar en infrastruktur för digital patologi som möjliggör AI-baserad förbättrad diagnostik, och EUCAIM ger bättre hantering av bilddata inom cancerfältet. För att möjliggöra den nya utvecklingen sker även justeringar av lagstiftningen, framför allt EHDS (European Health Data Space) som skapar ett europeiskt hälsodataområde med underlättad tillgång till hälsodata inom Europa. Sverige är ledande i flera av dessa projekt – vi bygger den digitala infrastrukturen för GDI och Bigpicture och vi samordnar så att data kan länkas mellan de olika projekten. Seminariet består av korta presentationer om de pågående initiativen följt av paneldiskussion och frågor från auditoriet.

Medverkande

Anna Hagwall, Projektledare humandata, Uppsala Universitet, SciLifeLab, NBIS, GDI

Richard Rosenquist Brandell, Professor, GMS, Karolinska Institutet, Karolinska sjukhuset

Johan Viklund, Teknisk chef, Uppsala Universitet, SciLifeLab, NBIS, Bigpicture

Katrine Riklund, Professor i radiologi, Umeå Universitet, EUCAIM

Åsa Johansson, Universitetslektor, Uppsala Universitet, SciLifeLab

Bengt Persson, Professor i bioninformatik och organisation, Uppsala Univeristet, SciLifeLab, NBIS, GDI

Joel Hedlund, Data director CMIV/AIDA, Linköpings Universitet, SciLifeLab, NBIS, Bigpicture, EUCAIM

Hur kan vi göra Sverige ledande inom precisions-medicinsk forskning?
2025-06-25 14:15 - 15:00 | B-huset, Campus Gotland, Cramérgatan 3, Visby, Sweden
Hur kan vi utnyttja den snabb utvecklingen inom genomik och multiomik-tekniker för att ställa mer precisa diagnoser och kunna erbjuda skräddarsydda behandlingar samtidigt som vi säkerställer att dessa banbrytande framsteg blir jämlikt tillgängliga för alla i Sverige?

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Genomik och multiomik-tekniker kommer i framtiden att kunna användas för att ställa mer specifika diagnoser och rekommendera mer riktade behandlingar, både för sällsynta sjukdomar, cancer och folksjukdomar. För att möjliggöra precisionsmedicin krävs både forskning och implementering inom sjukvården. Sverige har unika hälsodataregister och ett stort antal väletablerade biobanker, men för att möjliggöra mer individanpassad vård och behandling behövs storskaliga studier inom genomik, proteomik och metabolomik, så kallad multiomik. Dessutom måste denna data göras tillgänglig för forskare på ett transparent och säkert sätt. Vi behöver också bli bättre på att integrera forskning med hälso- och sjukvården för att snabbare kunna utveckla och implementera ny diagnostik och behandling. Precision Omics Initiative Sweden (PROMISE) är ett nytt nationellt initiativ som syftar till att göra Sverige ledande inom precisionsmedicinsk forskning.

Medverkande

Åsa Johansson, Dr., Uppsala Universitet, SciLifeLab, GMS

Richard Rosenquist Brandell, Professor, GMS, Karolinska Institutet, Karolinska sjukhuset

Tuuli Lappalainen, Professor, KTH, SciLifeLab

En nationell klinisk prövning inom precisionsmedicin - loket för att dra Sverige till globala täten
2025-06-26 09:00 - 10:30 | Cancer Mission Day, Birgers Gränd 9, Visby
Arrangeras av Genomic Medicine Sweden (GMS), SciLifeLab, Nollvision cancer – Testbed Sweden

Kliniska studier omsätter forskning i praktiken där precisionsmedicin genom rik diagnostik data matchar patienter med rätt behandling. Hur kan Sverige etablera en nationell struktur för precisionsbehandling och molekylär profilering till nytta för cancerpatienter?

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Sverige har väl utvecklad sjukvård, hög utbildningsnivå inom professionen, världsledande forskning med en hög tillit i hela ekosystemet från patient, hälso och sjukvård samt näringsliv. I Sverige finns utmaningar för utvecklingen av precisionsmedicin inom cancer: fragmenterat hälso- och sjukvårdssystem, utmanande legala förutsättningar för digital infrastruktur för strukturerad och automatiserad datainsamling från både hälso och sjukvården och forskningen. Genom att etablera en nationell prövning, FOCU.SE, kopplad till en explorativ plattformsstudie kan akademi, hälso- och sjukvård och näringsliv samarbeta för att utveckla nya processer för precisionsdiagnostik och precisionsmedicinska behandlingar.

Frågor som diskuteras är: Hur står sig Sverige jämfört med andra länder och varför är det viktigt att satsa på en nationell prövning? Vad är vinsterna för patient, hälso- och sjukvård och den akademiska forskningen? Varför är det viktigt för svenskt näringsliv?

Medverkande

Richard Rosenquist Brandell, Överläkare, professor, föreståndare GMS, Karolinska Institutet, Karolinska sjukhuset

Janne Lehtiö, Professor, SciLifeLab, Karolinska Institutet

Edvard Abel, Överläkare och centrumföreståndare SCCC

Jonas Claesson, Hälso- och sjukvårdsdirektör, Region Örebro län

Gunilla Andrew-Nielsen, Enhetschef Kliniska prövningar och licenser , Läkemedelsverket

Signe Friesland, Patientområdeschef/verksamhetschef, Tema Cancer, Karolinska Universitetssjukhuset

Malin Sjöberg Högrell (L), Regionråd, Region Uppsala

Emelie Antoni, Nordenchef, AstraZeneca, Styrelseordförande Lif

Anders Edsjö, Överläkare, Sektionschef klinisk patologi Processansvarig molekylär patologi Klinisk genetik, patologi och molekylär diagnostik, Medicinsk service, Region Skåne, GMS

AI och datadriven forskning – hur stärker vi vägen från forskning till hållbar samhällsnytta?
2025-06-26 14:15 - 15:00 | D-huset, Campus Gotland, Kaserngatan 1, Visby, Sweden
AI och datadriven forskning kan ge stora samhällsvinster genom bättre hälsa, beredskap och miljöskydd. För att möta utmaningar som åldrande befolkning, pandemier och biodiversitetskrisen krävs samlade insatser. Hur kan ny kunskap omsättas i praktisk och hållbar samhällsnytta?

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AI och datadriven forskning för hälsa och miljö – hur kan vi stärka övergången från forskning till hållbar samhällsnytta? AI och datadriven forskning accelererar mängden ny kunskap om hur livet fungerar. För att vi ska kunna använda kunskapen på ett ansvarsfullt och hållbart sätt behövs robusta system. I paneldiskussionen kommer vi att fokusera på – och samtala med experter om hur den nya kunskapen gör det möjligt att få genomslag inom hälsa och beredskap för biologiska kriser. Med samhällsutmaningar som åldrande befolkning, cancer och andra folksjukdomar, pandemiberedskap, antibiotikaresistens, miljögifter, biodiversitetskrisen behövs enade krafter där pågående satsningar inom precisionsmedicin, beredskap och planetens biologi behöver förstärkas nationellt.

Research seminar; SciLifeLab Fellow position in Advanced Therapy Medicinal Products (ATMP)
2025-08-19 09:00 - 12:00 | Navet, SciLifeLab Uppsala, SciLifeLab Uppsala, BMC C11, Husargatan 3, Uppsala, 75237, Sweden
Welcome to listen to the seminars and discussions of the candidates for the SciLifeLab Fellow position in Advanced Therapy Medicinal Products (ATMP) at Uppsala University.

Date: August 19, 2025

Location: The Triple room in SciLifeLab Navet, Entrance C11 at BMC, Husargatan 3, Uppsala. Or Zoom.

Registration

Please register to reserve a seat onsite or get the Zoom link to attend online.

Join the Zoom meeting by following the “Link to online event” in the Confirmation email. We will also send an e-mail reminder the day before the event with a button to “Join the Zoom meeting”.

Zoom attendees: You will enter a waiting room until the host opens the meeting. You will be muted and off camera upon entry. We kindly ask the participants to stay muted during the presentations and write questions in the Q&A field. The Host will address questions after each presentation.

Registration

Program

Program_250819_ATMP seminarDownload

BNMI 2025 Symposium – 4th annual meeting of the Bridging Nordic Microscopy Infrastructure
2025-08-19 09:00 - 2025-08-22 17:00 | Conference Centre Wallenberg, Medicinaregatan 20A, Gothenburg, 413 90, Sweden
Welcome to the BNMI 2025 Symposium – 4th annual meeting of the Bridging Nordic Microscopy Infrastructure

Whether early in your career or an experienced researcher, BNMI 2025 offers a unique opportunity to stay updated on cutting-edge imaging technologies, learn new techniques, and build valuable connections within the imaging community.

The program will feature a compelling mix of lectures, poster sessions, and selected short talks from poster presenters, covering topics from electron and light microscopy, X-ray imaging, to advanced image analysis. Attendees will have numerous opportunities to engage in both formal discussions and informal gatherings, enriching both scientific dialogue and networking. Sessions will focus on these key areas in imaging research:

Correlative Multimodal Imaging: Imaging across multiple scales

Super-resolution and Nanoscale Imaging: Innovations at the nanoscale

Mesoscopy: Capturing dynamic interactions within cells, organoids, tissues, and whol organisms

Smart Microscopy: From advanced image analysis to intelligent acquisition

New Frontiers: Exploring cutting-edge imaging applications

Join us in Gothenburg in August!

Registration

Event web page

Chemical Biology Seminar Series: "Collaborative drug discovery at NCATS
2025-08-21 14:00 - 15:00 | Gamma 2 Lunchroom, SciLifeLab, Tomtebodavägen 23, Solna, Sweden
Join us for an engaging seminar in the Chemical Biology Seminar Series featuring Dr. Matthew D. Hall, Scientific Director of the Division of Preclinical Innovation at the National Center for Advancing Translational Sciences (NCATS), NIH.

Short summary: First, I will speak about our translational science laboratories at NCATS, and how we collaborate. I will give some insight into the opportunities and the challenges of working with collaborators. Second, I’ll describe a recent research project as an example of early drug discovery – a new inhibitor for NNMT (N-nicotinamide methyltransferase). Third, I’ll touch on challenges and next steps for drug discovery tools – the need to embrace alternative methods (NAMS) and new modalities (such as gene therapy).

NOTE: We will meet up with individuals who do not have access to SciLifeLab in the reception at 13.50

Mithrl AI Co-Scientist for Accelerating Biological Discovery.
2025-08-22 16:00 - 17:00 | Online event via Zoom
Vivek Adarsh, Mithrl

NBIS and SciLifeLab Data Centre arrange an open SciLifeLab AI Seminar Series aimed at knowledge-sharing about Artificial Intelligence and applications in the Life Science community. The seminar series is open to everyone. The seminar is run over Zoom on the third Friday of the month during academic terms, typically between 10 and 11 am, with approx. 45 min presentation and 15 min discussion.

Abstract

​Despite the explosion of biological data from sequencing, imaging, and high-throughput experiments, extracting meaningful insights remains slow, manual, and heavily reliant on limited bioinformatics resources. Scientists often encounter bottlenecks that delay decision-making and limit the scope of discovery.

In this talk, we introduce the concept of an AI Co-Scientist—a set of autonomous agents that collaborates with researchers to analyze data, generate hypotheses, and uncover novel insights in minutes rather than months. We’ll explore real-world use cases where AI systems assist with tasks ranging from experimental planning and data preprocessing to functional analysis and scientific interpretation. We’ll also address practical challenges, including data quality, trust in AI-generated results, hallucinations, and integration into existing research workflows. By the end of the session, you’ll have a clearer understanding of how AI can partner with scientists to accelerate progress in the life sciences.

Seminar; Molecular Gateways of Immunity and Repair: Nuclear Signaling, Transcription, and Tissue Homeostasis
2025-08-25 14:00 - 15:15 | Campus Solna Biomedicum, Nils Ringertz (floor 3), Solnavägen 9, Solna, 171 65, Sweden
This seminar explores cutting-edge insights into nuclear signaling, immune regulation, and tissue homeostasis — highlighting key mechanisms of transcriptional control, T cell activation, and fibrosis in both health and disease.It brings together leading experts to discuss emerging molecular pathways and therapeutic targets that connect fundamental biology with translational applications.

“Targeting Fibroblast-Secreted Gremlin2 as a Novel Anti-Fibrotic Strategy”

Prof. Yuehai Ke, Dean of the Zhejiang University–University of Edinburgh Institute & Associate Dean of the School of Medicine at Zhejiang University

“The Role of Intranuclear Membraneless Organelles in T Cell Activation”

Prof. Lie Wang, Distinguished Professor at the School of Medicine, Zhejiang University, & Director of the Experimental Animal Center

“The Role of Nuclear Pore Complexes in Signaling-Driven Transcriptional Control”

Dr. Martin Kosar, Assistant Professor at the Zhejiang University–University of Edinburgh Institute & an Honorary Lecturer at the College of Medicine & Veterinary Medicine, University of Edinburg

Functional Precision Medicine and Precision Immune Oncology Strategies
2025-08-25 15:00 - 16:00 | Air&Fire, SciLifeLab Stockholm, Tomtebodavägen 23A, Solna, Sweden
Prof Taskén will cover research on functional precision medicine using cancer drug sensitivity screening to guide clinical decisions and on tumor immune evasion mechanisms aiming for future precision immune oncology approaches.

Biography

Professor Kjetil Taskén has been key in building Norway’s national cancer precision medicine initiative, now coordinates the Cancer Mission PRIME-ROSE project for DRUP-like clinical trials across Europe and will lead the Work Package on treatment in the Joint Action for Precision Cancer Medicine to start Nov 2025. He has authored>300 publications and is an inventor of >20 patents (h-index >70). He won the King Olav V’s Prize for Cancer Research in 2016, the University of Oslo Innovation Prize in 2023, the Oslo University Hospital Excellent Researcher Award in 2024, and is Vice-President of the Norwegian Academy of Science and Letters. Current research is in tumor immune evasion mechanisms and functional precision medicine for different solid and blood cancers. Kjetil is also member of SciLifelab’s International Advisory Board (IAB).

Host: Janne Lehtiö

[Spotlight seminar] Beyond Biological Sequence Space
2025-08-26 15:15 - 16:15 | Air&Fire, SciLifeLab Stockholm, Tomtebodavägen 23A, Solna, Sweden
Dr. Klára Hlouchová, Charles University in Prague, Czech Republic

Join us for an inspiring seminar with Dr. Klara Hlouchová, whose pioneering work delves deep into the “dark protein space“—the vast universe of unevolved amino acid sequences rarely touched by nature. Her group is using cutting-edge bioinformatics and experimental strategies to explore how early proteins formed using a primitive alphabet of just ~10 amino acids, and whether such minimal sets could support the folds and functions we see today. This seminar promises not just a glimpse into the origins of the protein world, but also fresh insights into the evolving logic of the genetic code and protein design. It’s a rare opportunity to connect with prebiotic molecular evolution at its most fundamental level.

Host: Ilaria Piazza, Ilaria.piazza@scilifelab.se

PLP Network Meeting 2025
2025-08-27 09:30 - 2025-08-28 13:00 | Nova Park, Gredelbyvägen 138, 741 71, Knivsta
Venue: Linné Conference room, Nova Park Gredelbyvägen 138, 741 71Knivsta,

The SciLifeLab Pandemic Laboratory Preparedness (PLP) program, launched in 2021, acts to address society’s need for efficient resource utilization, training, and education by fostering skills, implementing technologies, and providing equipment to ensure better preparedness for future pandemics.The PLP Network Meeting aims to strengthen the PLP network, identify areas requiring further development, and evaluate the program as a whole. It also offers valuable opportunities to exchange new ideas and foster collaborations among PLP network members.Transport and Accommodation is provided for registered participants. Bus transport will be organized from/to Cityterminalen in Stockholm, Uppsala University and Arlanda Airport (see timetable below)

Invited participants only

Program

The program below will be updated continuously

TimeAugust 27 2025, Venue: Linné Conference room9:30Registration10:00Welcome and introductionAlice Sollazzo, UU10:10SciLifeLab PLP Strategic AreaUlf Ribacke, UU10:45Get-to-know-each-other activity11:40Lunch12:30Session 1 – National and international initiativetsChair: Staffan Svärd, UU12:30Short talks from Panelists12:50Panel discussionJan Albert, KI; Jens Mattsson, FOI; Jessica Alm, KI, Sara Byfors, Public Health agency of Sweden13:30Short break13:40Title: Establishing a respiratory metagenomic laboratory network for clinical service and public health surveillanceJonathan Edgeworth, King´s College London, UK14:10Title: Human IG genetic variability, vaccination and pandemic preparednessGunilla B. Karlsson Hedestam, KI14:40QuizUlf Ribacke, UU15:10Coffee break15:40Session 2 – Emerging threats topics#1Chair: Åke Lundkvist, UU15:45Title: Preparing for Future Pandemics – The Aftermath of the COVID-19 VaccineKizzmekia S. Corbett-Helaire, Harvard T.H. Chan School of Public Health 16:15Title: Could mosquito-borne viruses be a risk to health in SwedenJenny Hesson, UU16:45Title: On “mu flu” and other emerging animal pathogensKarl Ståhl, SVA 17:15Check-in and free time18:30Mingle and poster session Linné Conference room and lounge19:30Dinner

TimeAugust 28, 2025, Venue: Linné Conference room9:00Session 3 – Emerging threats#2Chair: Sanna Koskiniemi, UU9:05Title: Antibiotic resistance pandemic(s): the importance of rapid diagnostics”Dan Andersson, UU9:35Title: Genetic Reassortment among Influenza A Viruses: Shaping Virus Fitness and EvolutionMahmoud Mohamed Naguib, Liverpool University/ UU10:05Coffee break and group discussionsUlf Ribacke, UU11:15Summary sessionModerator: Ulf Ribacke, UU12:00Lunch13:00End of the program and transport to Stockholm, Uppsala, Arlanda

Organizing committee

Ulf Ribacke, UU

Staffan Svärd, UU

Claudia Fredolini, KTH

Paula Mölling, Region Örebro

Antonio Rothfuchs, KI

Tobias Allander, KI

Sanna Koskiniemi, UU

Åke Lundqvist, UU

Alice Sollazzo, PLP-Coordinator, SciLifeLab

Transportation, busses

To Nova Park – August 27FromDepartureUppsala (BMC), Husargatan 3, entrance C1109:00Stockholm, Cityterminalen08:30Arlanda, T409:00From Nova Park – August 28ToDepartureUppsala (BMC), Husargatan 3, entrance C1113:00Stockholm, Cityterminalen13:00SciLifelab, Tomtebodavägen 23A, Solna13:00Arlanda, T412:20 (lunch to-go)

Workshop: How to communicate your research beyond the lab
2025-08-28 13:00 - 14:00 | Air&Fire, SciLifeLab Stockholm, Tomtebodavägen 23A, Solna, Sweden
We’re excited to invite you (SciLifeLab community only) to a practical and interactive workshop in Solna focused on how to effectively communicate your research to a broader audience.

Why this workshop?As researchers, we often spend so much time in the details of our work that it can be hard to see what’s most interesting or relevant to someone outside our field. This session is designed to help you identify and frame those stories, whether for public outreach, media visibility, or a strong social media post.

Whether you’re a PhD student, postdoc, or research engineer, this session is especially aimed at those who don’t usually take the spotlight but whose work absolutely deserves it.

Workshop themes

What makes your research interesting? Learn to identify the “hook” and explain it clearly to a non-scientific audience. Tips on relevant media outlets and news platforms where you can make your voice heard.

Writing for the general public Practice simplifying complex ideas without dumbing them down.

Social media confidenceGet hands-on tips for writing short, engaging posts (e.g., LinkedIn or Bluesky).

FormatShort presentations, interactive exercises, and peer feedback in a relaxed setting.

You’ll also learn how the SciLifeLab communications team can support your outreach efforts with tools, channels, and networks.

PreparationTo get the most out of the session, we’ll ask participants to bring a short, simplified description (max 200 words) of a finding or idea from their research that they’d like to share with the public.

More details will follow after registration.

Tentative date: August 28Duration: 1 hourLocation: SciLifeLab Solna (in person)Register here: First come, first served

OMOP as a standard for analytics, generating real-world evidence, and federated machine learning
2025-09-02 16:00 - 17:00
Eric Fey, Development Manager AI at Helsinki University Hospital

Abstract

In the rapidly evolving landscape of healthcare data analytics, the OMOP Common Data Model (CDM) has emerged as a game-changer, revolutionizing the way real-world evidence (RWE) is generated and utilized. The presentation will draw from the OMOP experience from Helsinki University Hospital (HUS) and outline key steps, required competencies, and infrastructure needed for implementation, as well as information on how to join and leverage the international OHDSI network in the process. The presentation will show how HUS has successfully navigated the process from data sources, through ETL (Extract, Transform, Load) to OMOP data, quality control, to the first federated real-world study, and further into swarm-learning for predictive modelling in precision medicine. Use cases covered will include participation in DARWIN, an international OMOP study on immune checkpoint inhibitor uptake in metastatic non-small cell lung cancer (iCAN mNSCLC study-a-thon), and a swarm learning study across the Finnish university hospitals to cooperatively build a predictive model in acute myeloid leukaemia (AML).

Biography

Eric Fey, PhD, MEng is a distinguished scientists in systems biology and medicine, currently spearheading the development of AI applications and federated learning at the Helsinki University Hospital. His roles include the Data Team Lead at the iCAN Digital Precision Cancer Medicine flagship, University of Helsinki; AI Development Manager, HUS Helsinki University Hospital; and National Node Lead, OHDSI Finland. With a PhD in Engineering and a strong background in system biology and data science, Eric has a proven track record in academia, entrepreneurship, and industry, including the 2017 Irish Laboratory Award for Collaboration Achievement, and a significant role as Assistant Professor at University College Dublin School of Medicine. His innovative work in establishing the swarm-learning capabilities across the Finnish university hospitals and a published proof-of-concept that mathematical models of cancer signalling can outperform classical biochemical biomarkers demonstrate his commitment to advancing precision medicine through technology.

Registration

Please register, the Confirmation email provides a Zoom link to the online event.

Register

About Clinical Talks

Clinical Talks returns with a new season!

After seven successful seasons and over seventy dedicated speakers, we are excited to continue showcasing the contributions of our diverse clinical, academic, and industry life science community. This season will feature ten insightful talks following our well-established format. The overarching theme is “How to Achieve Feasible Implementation.”

Sessions will be held monthly on Fridays from 09:00 a.m. to 09:30 a.m. via Zoom, with occasional exceptions. Each talk will be followed by an engaging Q&A session, moderated by standing host Rikard Fred and a guest moderator with subject matter expertise to enrich the discussion.

In today’s rapidly evolving post-pandemic landscape, exploring how academic, clinical, and industry research, combined with technological advancements, can drive practical and sustainable solutions is crucial.

Join us for an opportunity to gain fresh insights, expand your knowledge, and connect with experts shaping the future of life sciences!

The SciLifeLab’s Precision Medicine Capability organises Clinical Talks.
