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DTSTART;TZID=Europe/Stockholm:20211108T093000
DTEND;TZID=Europe/Stockholm:20211108T103000
DTSTAMP:20260404T143105
CREATED:20210609T090521Z
LAST-MODIFIED:20210826T100254Z
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SUMMARY:Career path discussions with Jennifer Lippincott-Schwartz
DESCRIPTION:Jennifer Lippincott-Schwartz from the Howard Hughes Medical Institute will give an account of her career path and discuss with students and postdocs at 09.30 in the SciLifeLab Air&Fire auditorium. Since the number of places is limited\, please register below to participate in this session. \n\n\n\n\n\n\n\nRegister\n\n\n\n\n\n\n\nUsing cutting-edge\, superresolution imaging technology to visualize cellular activity at the nano-scale\, Lippincott-Schwartz lab has redefined how we look at protein dynamics in the cell. When describing her mentorship philosophy\, Jennifer comments that she encourages her group members to develop their own projects. It is only when a colleague feels that he or she “owns” the project that real dedication\, determination\, and creativity emerge. In developing projects\, she considers it is important to build on the strengths and interests of students and postdocs\, rather than focusing exclusively on a group leader’s specific interests at the time. \n\n\n\nThe annual lecture series is set up in the recognition of the development of electron microscopy and will be delivered by eminent scientists in the field of structural biology and molecular visualisation. The event is open to anyone. The main lecture will take place at 4.00pm in the Biomedicum Lecture Theatre. \n\n\n\nContact \n\n\n\nAlexey Amunts\, amunts@scilifelab.se
URL:https://www.scilifelab.se/event/career-path-discussions-with-jennifer-lippincott-schwartz/
LOCATION:Air&Fire\, SciLifeLab Stockholm\, Tomtebodavägen 23A\, Solna\, Sweden
CATEGORIES:Event
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20211108T151500
DTEND;TZID=Europe/Stockholm:20211108T163000
DTSTAMP:20260404T143105
CREATED:20211005T080424Z
LAST-MODIFIED:20211005T080541Z
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SUMMARY:The Svedberg seminar series: Ass. Prof. Maria Kasper
DESCRIPTION:Karolinska Institutet\, Department of Cell and Molecular Biology\, Sweden \n\n\n\nLINK TO SEMINAR   \n\n\n\n\n\n\n\n\n\nMaria Kasper is Associate Professor at the Karolinska Institutet in Stockholm\, Department of Cell and Molecular Biology. She received her PhD at the University of Salzburg in genetics\, with the majors in human genetics and molecular tumor biology. She came to Sweden in 2007\, where she spent a fruitful postdoctoral time in Rune Toftgårds lab\, and in 2013 she started her own lab focusing on skin\, stem cell biology and single-cell RNA sequencing. In 2016\, her lab pioneered the use of single-cell transcriptomics in the organ skin and has overall contributed with important work in skin biology and regenerative medicine. Maria has received a number of national recognitions such as the Framtidens Forskningsledare from SSF\, Ragnar Söderberg Fellow in Medicine and the CIMED young investigator award\, as well as the prestigious international LEO Foundation Gold Award for outstanding skin research. Since 2020\, she also coordinates together with Fiona Watt the Human Cell Atlas bionetwork for the organ skin. \n\n\n\nDecoding the molecular anatomy of skin\n\n\n\nSkin architecture and its function are determined by a rich variety of epithelial\, mesenchymal and immune cells that together orchestrate skin homeostasis\, including cyclical hair growth and barrier function. Previously\, my lab generated a comprehensive molecular and spatial atlas of epithelial and stromal cells during hair growth and rest. These studies revealed underlying molecular programs during progenitor-cell commitment and lineage differentiation\, as well as spatiotemporal fibroblast heterogeneity and potential epithelial-stromal interactions. The importance of cell-type specific signaling during homeostasis\, and the unrecognized potential of cell-type restricted signaling-changes were exemplified by our recent discovery of how to induce new hair follicles in adult mouse skin by modulating a single signaling pathway. Building on the molecular knowledge and computational skills gained\, our ongoing work uncovers new insights in the molecular orchestration of embryonic hair follicle development\, as well as the coordination of adult skin stem cell differentiation by tissue resident immune cells.Host: Gabriella Lindgren\, SLU
URL:https://www.scilifelab.se/event/the-svedberg-seminar-series-ass-prof-maria-kasper/
LOCATION:Online event via Zoom
CATEGORIES:Event
ORGANIZER;CN="The Svedberg Seminar Series":MAILTO:thesvedberg@scilifelab.uu.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20211108T160000
DTEND;TZID=Europe/Stockholm:20211108T170000
DTSTAMP:20260404T143105
CREATED:20210609T090256Z
LAST-MODIFIED:20210826T100440Z
UID:10000399-1636387200-1636390800@www.scilifelab.se
SUMMARY:Annual lecture in structural biology by Jennifer Lippincott-Schwartz
DESCRIPTION:Jennifer Lippincott-Schwartz from the Howard Hughes Medical Institute will give the lecture entitled ‘Emerging Imaging Technologies to Study Cell Architecture\, Dynamics\, and Function’ on November 8\, 2021 at 4.00pm in the Biomedicum lecture theatre. Using cutting-edge\, superresolution imaging technology to visualize cellular activity at the nano-scale\, Lippincott-Schwartz lab has redefined how we look at protein dynamics in the cell. \n\n\n\nThe annual lecture series is set up in the recognition of the development of electron microscopy and will be delivered by eminent scientists in the field of structural biology and molecular visualisation. The event is open to anyone. A holder of the lectureship will particularly spend time with students and postdocs. Therefore\, Jennifer will also give an account of her career path and discuss with students and postdocs at 09.30am in the SciLifeLab Air&Fire auditorium. \n\n\n\nAbout Jennifer Lippincott-Schwartz \n\n\n\nResearch in Lippincott-Schwartz lab is aimed at developing live cell imaging to elucidate the dynamics inside eukaryotic cells. She pioneered photobleaching and photoactivation techniques which allow investigation of subcellular localization\, turnover and trafficking of important cellular proteins related to membrane compartmentalization. Her work on photoactivatable GFP led to the development of one of the first super-resolution imaging technologies\, photoactivation localization microscopy. Jennifer then used her methods to assess organelles dynamics and interactions revealing a novel picture of how the peripheral endoplasmic reticulum is structured. In addition\, the Golgi apparatus is central to Jennifer’s studies\, where her team demonstrated a novel pathway of enzymes recycling important for the organelle’s biogenesis and maintenance. Together\, the obtained findings have provided insights into how genetic diseases affect proteins that help shape the endoplasmic reticulum. \n\n\n\nIn 2016\, Lippincott-Schwartz initiated the Neuronal Cell Biology Program at Janelia. She is Fellow of the American Academy of Arts and Sciences Fellow\, and also Honorary Fellow of the Royal Microscopical Society.  \n\n\n\nBackground information \n\n\n\nThe annual lecture in structural biology is named in honour of Fritiof Sjöstrand\, who pioneered the electron microscopy in Sweden. In the early 1950’s he developed an advanced microtome for thin sectioning\, and by applying it for structural analysis of mitochondria produced a major breakthrough with the determination of the double membrane system. He then engineered a next generation of microtomes using electrical heating of the specimen to advance it toward the knife\, and the instrument became known as the ‘‘Sjöstrand Ultramicrotome”. In 1959\, Fritiof Sjöstrand moved to UCLA\, where his research focused on mitochondrial membranes and retinal synapses. Fritiof Sjöstrand founded and was Editor in Chief of the Journal of Structural Biology for 33 years. Lectures in the previous years were given by Venki Ramakrishnan and Jennifer Doudna. \n\n\n\nContact \n\n\n\nAlexey Amunts\, amunts@scilifelab.se
URL:https://www.scilifelab.se/event/emerging-imaging-technologies-to-study-cell-architecture-dynamics-and-function/
LOCATION:Biomedicum\, Solnavägen 9\, Solna
CATEGORIES:Event
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20211109T100000
DTEND;TZID=Europe/Stockholm:20211109T110000
DTSTAMP:20260404T143105
CREATED:20211102T153126Z
LAST-MODIFIED:20211102T153315Z
UID:10000478-1636452000-1636455600@www.scilifelab.se
SUMMARY:The curious case of a leak channel that never wants to be open
DESCRIPTION:Stephan Pless\, PhD \n\n\n\nProfessor of Molecular and Cellular PharmacologyUniversity of Copenhagen\, Denmark \n\n\n\nThe Pless lab is interested in the molecular function and pharmacology of ion channels. These complex membrane proteins regulate cellular excitability by controlling the flux of ions across cell membranes in response to a diverse set of stimuli. Their dysfunction is associated with numerous diseases\, resulting in an ever-increasing demand for new drugs targeting these fascinating molecules. \n\n\n\n\n\n\n\nDownload
URL:https://www.scilifelab.se/event/the-curious-case-of-a-leak-channel-that-never-wants-to-be-open/
LOCATION:Air&Fire\, SciLifeLab Stockholm\, Tomtebodavägen 23A\, Solna\, Sweden
CATEGORIES:Event
ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2021/11/Skärmavbild-2021-11-02-kl.-16.27.31.png
ORGANIZER;CN="Molecular Biophysics Stockholm":MAILTO:join-mbp@scilifelab.se.
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20211109T150000
DTEND;TZID=Europe/Stockholm:20211109T160000
DTSTAMP:20260404T143105
CREATED:20211101T085537Z
LAST-MODIFIED:20211101T085648Z
UID:10000476-1636470000-1636473600@www.scilifelab.se
SUMMARY:Insights into EMBO’s Fellowship Programme
DESCRIPTION:Kelly Sheehan-Rooney\, Head of the Fellowship Programme at EMBO\, will give an overview of the eligibility and evaluation criteria of EMBO’s Postdoctoral Fellowships\, Scientific Exchange Grants\, and the New Venture Fellowships. She will also give some top tips for grant writing\, and an insight into her career move from academic research to international research development. \n\n\n\nKelly Sheehan-Rooney is Head of the Fellowship Programme at EMBO. She obtained her PhD in Developmental Biology from the University of Manchester\, UK\, before carrying out a three-year postdoctoral position at the University of Texas in Austin\, USA. Now with 10 years’ experience in international research development\, Kelly has worked with thousands of scientists across the world; supporting them in their various careers\, building collaborative networks\, and fostering a research environment where scientists can achieve their best work. \n\n\n\nResearchers in all stages of their career are welcome to attend and could find the talk useful. The fellowships are a great opportunity for early-stage researchers as well as for group leaders to further their research interests and consider new avenues to expand into high quality research ideas. \n\n\n\nMeeting Flyer
URL:https://www.scilifelab.se/event/insights-into-embos-fellowship-programme/
LOCATION:Online event via Zoom
CATEGORIES:Event
ORGANIZER;CN="SciLifeLab Solna PhD & Postdoc Council":MAILTO:phd-council@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20211110T140000
DTEND;TZID=Europe/Stockholm:20211110T150000
DTSTAMP:20260404T143105
CREATED:20211014T151000Z
LAST-MODIFIED:20211020T130718Z
UID:10000466-1636552800-1636556400@www.scilifelab.se
SUMMARY:[Drug Discovery Seminar] How protein degradation led to faculty entrepreneurship at Yale: A personal Perspective
DESCRIPTION:SciLifeLab Drug Discovery Seminars\, hosted by the DDD platform\, is a series of educational lectures about recent developments\, technologies\, and trends in drug discovery and development that aims to enlighten\, and spark a discussion\, within the Swedish drug discovery community. \n\n\n\nCraig Crews\n\n\n\n\n\n\n\n \n\n\n\nJohn C. Malone Professor of Molecular\, Cellular\, and Developmental Biology and Professor of Chemistry\, of Pharmacology\, and of Management; Executive Dirictor\, Yale Center for Molecular Discovery\, Yale University \n\n\n\nAbstract \n\n\n\nProf. Crews is the 2021 recipient of the Scheele prize from the Swedish Pharmaceutical Society for his seminal work on protein degradation. In this talk Prof. Crews will discuss his efforts to translate research from his lab into new biopharma ventures.  To date\, these entrepreneurial  efforts have resulted in a FDA approved drug (Kyprolis) and a new therapeutic modality (PROTACs).  While each of his four companies has been launched based on different science\, they have all followed a similar business model and Prof. Crews will discuss efforts at Yale to ’systematize’ faculty entrepreneurism via a core ‘biotech accelerator’ facility. \n\n\n\nregistration\n\n\n\nBiography \n\n\n\nCrews is the John C. Malone Professor of Molecular\, Cellular and Developmental Biology and holds joint appointments in the departments of Chemistry and Pharmacology at Yale University. He graduated from the U.Virginia with a B.A. in Chemistry and received his Ph.D. from Harvard University in Biochemistry. Dr. Crews has a foothold in both the academic and biotech arenas; on the faculty at Yale since 1995\, his laboratory has pioneered the use of small molecules to control intracellular protein levels.  \n\n\n\nIn 2003\, he co-founded Proteolix\, Inc.\, whose proteasome inhibitor\, Kyprolis™ received FDA approval for the treatment of multiple myeloma. Since Proteolix’s purchase by Onyx Pharmaceuticals in 2009\, Dr. Crews has focused on a new drug development technology\, which served as the founding intellectual property for his latest New Haven-based biotech venture\, Arvinas\, Inc.  \n\n\n\nCurrently\, Dr. Crews serves on several editorial boards and was Editor of Cell Chemical Biology (2008-2018). In addition\, he has received numerous awards and honors\, including the 2013 CURE Entrepreneur of the Year Award\, 2014 Ehrlich Award for Medicinal Chemistry\, 2015 Yale Cancer Center Translational Research Prize\, a NIH R35 Outstanding Investigator Award (2015)\, the AACR Award for Chemistry in Cancer Research (2017)\, Khorana Prize from the Royal Society of Chemistry (2018)\, Pierre Fabre Award for Therapeutic Innovation (2018)\, the Pharmacia-ASPET Award for Experimental Therapeutics (2019)\, the Heinrich Wieland Prize (2020) and the Scheele Prize (2021). In 2019\, he was named an American Cancer Society Professor.
URL:https://www.scilifelab.se/event/drug-discovery-seminar-faculty-entrepreneurship-at-yale-a-personal-perspective/
LOCATION:Air&Fire\, SciLifeLab Stockholm\, Tomtebodavägen 23A\, Solna\, Sweden
CATEGORIES:Event
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20211112T130000
DTEND;TZID=Europe/Stockholm:20211112T143000
DTSTAMP:20260404T143105
CREATED:20211029T062301Z
LAST-MODIFIED:20211029T062304Z
UID:10000475-1636722000-1636727400@www.scilifelab.se
SUMMARY:Open webinar: How can SciLifeLab\, MAX IV and ESS contribute to drug discovery and development?
DESCRIPTION:During this seminar the three large-scale research infrastructures – SciLifeLab\, MAX IV and ESS – will present their offer to the Life Science industry in form of advanced technologies in the shape of research infrastructure\, as well as relevant data support and structures. Together they can provide technologies ranging from genomics\, proteomics\, genome engineering and drug discovery\, to X-ray beamlines and the most powerful neutron source worldwide. \n\n\n\nThe webinar is a joint venture between Lif and InfraLife\, the initiative that serve as a hubconnecting stakeholders\, displaying the potential of the advanced technologies\, and making these unprecedented tools accessible to be utilized in addressing complex research questions.Who should attend? \n\n\n\nEveryone who works within pharma industry and the Life Science-ecosystem in Sweden and iscurious about what services these three major national infrastructures can offer and how to starta research project. \n\n\n\nRegistration\n\n\n\nPreliminary program: \n\n\n\nWelcomeFrida Lundmark\, Lif \n\n\n\nThe InfraLife projectElin Jonsson and Josefin Lundgren Gawell\, project coordinators InfraLife \n\n\n\nSciLifeLab – possibilities in drug discovery & DevelopmentPer Arvidsson\, Director Drug Discovery & Development platform\, SciLifeLab \n\n\n\nCryo-EM recent development and great possibilities for drug researchMarta Carroni\, Platform Director\, Cell and Molecular Imaging\, SciLifeLab \n\n\n\nThe MAX IV synchrotron and possibilities for Life ScienceSelma Maric\, Industrial Relations\, Life Science and Soft Matter\, MAX IV \n\n\n\nNeutron research possibilities for drug development and the European Spallation Source (ESS)Zoë Fisher\, Group Leader for Deuteration and Macromolecular Crystallisation\, ESS \n\n\n\nIndustry examples from X-ray and neutron experimentsEmanuel Larsson\, Postdoctoral fellow\, Solid Mechanics\, Expert Lunarc (Centre for Scientific and Technological Computing)\, Lund University \n\n\n\nTime for questions \n\n\n\nWrap up and future perspectives
URL:https://www.scilifelab.se/event/open-webinar-how-can-scilifelab-max-iv-and-ess-contribute-to-drug-discovery-and-development/
LOCATION:Online event via Zoom
CATEGORIES:Event
ATTACH;FMTTYPE=image/jpeg:https://www.scilifelab.se/wp-content/uploads/2020/05/AdobeStock_297709311-scaled.jpeg
ORGANIZER;CN="InfraLife":MAILTO:events@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20211112T140000
DTEND;TZID=Europe/Stockholm:20211112T150000
DTSTAMP:20260404T143105
CREATED:20211014T151650Z
LAST-MODIFIED:20211020T131013Z
UID:10000467-1636725600-1636729200@www.scilifelab.se
SUMMARY:[Drug Discovery Seminar] PROTAC Degraders: From Fundamental Chemical Biology to Translation and Entrepreneurship
DESCRIPTION:SciLifeLab Drug Discovery Seminars\, hosted by the DDD platform\, is a series of educational lectures about recent developments\, technologies\, and trends in drug discovery and development that aims to enlighten\, and spark a discussion\, within the Swedish drug discovery community. \n\n\n\nAlessio Ciulli\n\n\n\nProfessor of Chemical Structural Biology \n\n\n\nCentre for Targeted Protein Degradation\, School of Life Sciences\, Division of Biological Chemistry and Drug Discovery\, University of Dundee \n\n\n\n \n\n\n\nAbstract\n\n\n\nProteolysis-targeting chimeras (PROTACs) are a new class of chemical tools and drugs that target disease-causing proteins for degradation. They are designed to harness the cell’s natural disposal system (the ubiquitin-proteasome) to specifically remove proteins. A PROTAC is a two-headed (i.e. bifunctional) molecule where one end binds an enzyme (an E3 ubiquitin ligase) and the other binds the target protein\, bringing the two proteins into close proximity as a ternary complex. The ligase is then able to label the target protein for ubiquitination and so degradation by the cell’s disposal system. Whereas conventional drugs only inhibit disease proteins by binding and locking up their most important functional parts for the duration of the drug’s action\, PROTACs can bind at any positions and rapidly cause the disease protein’s permanent and long-lasting destruction. Due to this revolutionary mode of action\, PROTACs can attack targets previously thought ‘undruggable’.  \n\n\n\nIn my lecture\, I will outline some key discoveries from my laboratory that have advanced the chemical structural biology of PROTACs\, and are providing fundamental insights into our understanding of their molecular recognition\, mechanism of action and drug design. I will also offer insights from our efforts to translate this fundamental science into molecular therapeutics to benefit patients\, via both partnerships with big pharma and formation of company spin-outs. Finally I will highlight the vision and mission of our recently announced new Centre for Targeted Protein Degradation at Dundee. \n\n\n\nShort Bio\n\n\n\n\n\n\n\nAlessio Ciulli holds the Personal Chair of Chemical Structural Biology at the School of Life Sciences\, University of Dundee. He is also the Director of the newly announced Dundee’s Centre for Targeted Protein Degradation (CeTPD). Dr Ciulli’s laboratory has made important contributions to selective chemical intervention on protein-protein interactions targets and to the development of proteolysis-targeting chimeric molecules (PROTACs) as a viable strategy for targeted protein degradation. Amongst his most significant discoveries are the fragment-based design of ligands for the E3 ligase von Hippel-Lindau (VHL)\, and their use to design one of the first VHL-based PROTACs: the BET degrader MZ1. Dr Ciulli’s Lab later illuminated fundamental insights into PROTACs’ mechanism of action\, solving the first crystal structure of a PROTAC ternary complex. Dr. Ciulli is the scientific founder of Amphista therapeutics\, a company that develops new protein degradation platforms. Before joining Dundee\, Dr Ciulli was a group leader at the University of Cambridge\, where he previously earned his PhD degree. Amongst his honours are the EFMC Prize for Young Medicinal Chemist in Academia\, the RSC Capps Green Zomaya Award in medicinal computational chemistry\, and election as Fellow of the Royal Society of Chemistry. \n\n\n\n \n\n\n\nRegistration
URL:https://www.scilifelab.se/event/drug-discovery-seminar-protac-degraders-from-fundamental-chemical-biology-to-translation-and-entrepreneurship/
LOCATION:Navet\, SciLifeLab Uppsala\, SciLifeLab Uppsala\, BMC C11\, Husargatan 3\, Uppsala\, 75237\, Sweden
CATEGORIES:Event
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20211115T090000
DTEND;TZID=Europe/Stockholm:20211115T093000
DTSTAMP:20260404T143105
CREATED:20211111T133009Z
LAST-MODIFIED:20211111T133419Z
UID:10000489-1636966800-1636968600@www.scilifelab.se
SUMMARY:Meet the BioInnivation Institute
DESCRIPTION:BioInnovation Institute (BII) is an international commercial foundation with a non-profit objective supported by the Novo Nordisk Foundation. BII operates an incubator to accelerate world-class life science innovation that drives the development of new solutions through the creation of life science start-ups for the benefit of people and society. BII offers help to early-stage projects and start-ups in health tech\, bio-industrials and therapeutics through their two programs VentureLab and Creation House.  \n\n\n\nThe programmes are open for applications twice a year. The next application deadlines are November 25th 2021 for Creation House and February 24th 2022 for Venture Lab. \n\n\n\nLearn more about the call on Monday\, November 15\, 09:00.
URL:https://www.scilifelab.se/event/meet-the-bioinnivation-institute/
LOCATION:Online event via Zoom
CATEGORIES:Event
ORGANIZER;CN="External Relations Office":MAILTO:externalrelations@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20211122T083000
DTEND;TZID=Europe/Stockholm:20211122T170000
DTSTAMP:20260404T143105
CREATED:20211018T141327Z
LAST-MODIFIED:20211104T080816Z
UID:10000468-1637569800-1637600400@www.scilifelab.se
SUMMARY:DDLS Conference: Strategic research areas - postponed!
DESCRIPTION:Join us at the first conference within The SciLifeLab and Wallenberg national program for Data-Driven Life Science! \n\n\n\n\n\n\n\nThe practice of life science is continuously becoming more data-dependent. The amount and complexity of data is growing exponentially\, and more scientific discoveries are enabled when data is openly available to researchers across the world. This is the basis for the SciLifeLab and Wallenberg National Program on Data-Driven Life Science (DDLS). \n\n\n\nThe program focuses on four strategic areas for data-driven research\, all of which are essential for improving the lives of people as well as animals and nature\, detecting and treating diseases\, protecting biodiversity and creating sustainability:  \n\n\n\nCell and molecular biologyEpidemiology and infection biologyEvolution and biodiversityPrecision medicine and diagnostics\n\n\n\n \n\n\n\nThe conference will focus on enthusing research within the four research areas and aims to bring together researchers within the field for discussion and sharing the latest within the research areas. The meeting will offer an exciting compilation of keynotes\, special lectures within the four fields and opportunities to meet and discuss with prominent researchers.  \n\n\n\nAnyone with interest in the data-driven research field is welcome to participate. The full-day conference will be virtual (Zoom). \n\n\n\n \n\n\n\nThe program with confirmed speakers will be available shortly. \n\n\n\n\n\n\n\nThe conference is part of the SciLifeLab and Wallenberg national program for the DDLS program\, funded by the Alice and Knut Wallenbergs Foundation.
URL:https://www.scilifelab.se/event/ddls-conference-strategic-research-areas/
CATEGORIES:Event
LOCATION:
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20211122T151500
DTEND;TZID=Europe/Stockholm:20211122T163000
DTSTAMP:20260404T143105
CREATED:20211110T141705Z
LAST-MODIFIED:20211122T105625Z
UID:10000484-1637594100-1637598600@www.scilifelab.se
SUMMARY:The Svedberg seminar series: Prof. Tuuli Lappalainen
DESCRIPTION:Science for Life Laboratory\, Department of Gene Technology\, KTH Royal Institute of Technology\, Stockholm\, Sweden \n\n\n\nNew York Genome Center\, New York\, USA \n\n\n\nLINK TO SEMINAR \n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\nTuuli Lappalainen is a Professor in Genomics at KTH Royal Institute of Technology\, an Associate Faculty Member at the New York Genome Center\, and the Director of the National Genomics Infrastructure of SciLifeLab. She is also an Adjunct Professor at the Department of Systems Biology at Columbia University. \n\n\n\nHer research focuses on functional genetic variation in human populations and its contribution to traits and diseases. She has pioneered the intergration of large-scale genome and transcriptome sequencing data to understand how genetic variation affects gene expression\, providing insight to cellular mechanisms underlying genetic risk for disease. \n\n\n\n\n\n\n\nFunctional variation in the human genome: lessons from the transcriptome\n\n\n\nDetailed characterization of molecular and cellular effects of genetic variants is essential for understanding biological processes that underlie genetic associations to disease. A particularly scalable approach has been linking genetic variants to effects in the transcriptome that is amenable for scalable measurements in human populations and in experimental settings\, including at the single cell level. Our multi-omic analysis in human cohorts in the TOPMed project has identified genetic and environmental effects on molecular variation together with their complex interplay with clinical phenotypes. Furthermore\, in this talk I will discuss how CRISPRi silencing of regulatory elements followed by single-cell analysis provides novel insights of mechanisms of genetic associations to complex traits. Altogether\, these diverse approaches for integration genome and transcriptome data uncover functional genetic architecture of human traits\, and enhances our understanding of both basic biology and precision medicine applications. \n\n\n\nHost: Jessica Nordlund\, Uppsala University
URL:https://www.scilifelab.se/event/the-svedberg-seminar-series-prof-tuuli-lappalainen/
LOCATION:Online event via Zoom
CATEGORIES:Event
ORGANIZER;CN="The Svedberg Seminar Series":MAILTO:thesvedberg@scilifelab.uu.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20211123T100000
DTEND;TZID=Europe/Stockholm:20211123T110000
DTSTAMP:20260404T143105
CREATED:20211110T112711Z
LAST-MODIFIED:20211123T124213Z
UID:10000483-1637661600-1637665200@www.scilifelab.se
SUMMARY:SciLifeLab AI Seminar Series: A sneak peek into the future of AI-assisted life science
DESCRIPTION:SciLifeLab Data Centre hosts a seminar series on the topic of applied AI in life science research. SciLifeLab AI Seminar Series combines scientific highlights from SciLifeLab-affiliated researchers and invited experts on the general topic of AI applications in Life Science.  \n\n\n\nThe seminar will be held physically at SciLifeLab Gamma 7 lunch room in Solna and online via Zoom. Physical participation is recommended since some AI models are not allowed to be shown via streaming and there will be no recording after the seminar according to the live demonstration policy of OpenAI.  \n\n\n\nContact: Prof. Ola Spjuth\, AI coordinator\, SciLifeLab Data Center. \n\n\n\nSpeaker: Wei OUYANGKTH Royal Institute of Technology and Science for Life Laboratory \n\n\n\nAbstract\n\n\n\nHave you imagined how AI may one day help you with your research by proposing new ideas\, running experiments\, analyzing data\, and even writing manuscripts? While current AI systems are too weak for those tasks\, we are closer than ever before! \n\n\n\nIn June 2020\, OpenAI revealed the most advanced AI model in the world\, GPT-3. It is the largest natural language processing model ever created with 175 billion parameters\, trained on about 45TB of text data\, and it cost $12 million for a single training run that may be utilized and reused for many tasks. Not only are these numbers impressive\, its “text in\, text out” interface can be used as a general purpose tool for almost any language task with impressively good performance. With the newly released Codex model (a descendant of GPT-3)\, it can even generate source code in popular programming languages by following instructions in natural languages\, e.g.\, English. GPT-3 not only brings us to a new paradigm of AI-assisted coding\, but it also has a great potential to address long-standing challenges in deep learning about generalization and interpretability. \n\n\n\nWe are excited to share with you what we have learned so far about GPT-3 and its applications in life science. In this talk\, we will give you an overview and discuss the promises and pitfalls of GPT-3. You will also see live demos in biomedical applications\, such as processing genomic sequences\, analyzing microscopy images\, and creating user-friendly software with graphical user interfaces (GUIs). Hopefully\, this session will serve as inspiration for your own research\, serve as a basis for discussion about AI in life science\, and convey how these tools may accelerate data-driven life science at SciLifeLab. \n\n\n\nBiography\n\n\n\nWei OUYANG is a researcher in Prof. Emma Lundberg’s group at the Science for Life Laboratory and KTH Royal Institute of Technology. He has a diverse background across several different fields including material science\, computer science and advanced microscopy imaging. In 2018\, Dr. Ouyang obtained his PhD in computational image analysis at Institut Pasteur\, Paris where he mainly focuses on applying deep learning for super-resolution microscopy. During this period\, he developed a deep learning method called ANNA-PALM which massively accelerates super-resolution localization microscopy by 100x. To address the challenges in the dissemination of AI tools\, he developed an open-source computational platform\, ImJoy\, which makes deep learning tools easier to build and more accessible to the user. He is actively involved in consortiums and community activities for promoting more open\, scalable\, accessible and reproducible scientific tools. Dr Ouyang has been focusing on AI augmented microscopy imaging and data-driven whole cell modeling. More recently\, he is excited about the recent progress in the field of AI and has a knee interest in exploring the next generation of data-driven life science powered by AI\, robotics\, blockchain and decentralized applications. \n\n\n\nRegister here
URL:https://www.scilifelab.se/event/scilifelab-ai-seminar-series-wei-ouyang/
CATEGORIES:Event
ORGANIZER;CN="SciLifeLab Data Centre":MAILTO:datacentre@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20211126T090000
DTEND;TZID=Europe/Stockholm:20211126T093000
DTSTAMP:20260404T143105
CREATED:20211014T115823Z
LAST-MODIFIED:20211014T120713Z
UID:10000465-1637917200-1637919000@www.scilifelab.se
SUMMARY:Clinical Talks: The road towards precision medicine in Sweden
DESCRIPTION:On November 26\, we will host Karolinska Institutet (KI) Professor Richard Rosenquist Brandell. In addition to his academic research and clinical work\, he also co-founded the Genomic Medicine Sweden (GMS) initiative and serves as the Director of GMS. Richard will share his insights on Sweden’s national strategy to implement precision medicine into our healthcare environment and pave the way for the amazing potential the approach has to offer. To benefit from the sustainable advantages of tailored and efficient use of diagnostics and treatment options\, Sweden needs to prepare our society for the legal challenges and infrastructures necessary to support and enable this transformation. \n\n\n\nRead more about clinical talks\n\n\n\nRichard Rosenquist Brandell\, MD\, PhD\, is Professor of Clinical Genetics at Karolinska Institutet\, Senior Physician at Karolinska University Hospital and director of Genomic Medicine Sweden\, a national infrastructure for implementation of precision medicine. He obtained his MD degree in 1996\, and later his PhD in Medicine in 1998\, from Umeå University. In 2000 Richard joined Uppsala University Hospital (“Akademiska Sjukhuset”) and in 2007 became a Professor at the Department of Immunology\, Genetics and Pathology\, Uppsala University. In April 2017\, he relocated to the Karolinska University Hospital as a Senior Physician and Professor. Richard’s work focuses on hematological malignancies and utilizing high-throughput sequencing technologies\, his team has identified novel prognostic and predictive biomarkers that have significantly improved patient risk-stratification.  Dr Rosenquist Brandell is also a member of the Nobel Assembly at Karolinska Institutet. \n\n\n\nGenomic Medicine Sweden (GMS) started as a bottom-up initiative within the national Clinical Genomics Platform (previously named the Diagnostics Development platform) at the Swedish Science for Life Laboratory (SciLifeLab). In 2017 and 2018 discussions with funding agencies\, decision-makers\, healthcare providers\, patient organisations\, universities\, and industry led to the founding of GMS as a national venture. GMS strategic mission is to foster collaboration between healthcare providers\, academia\, patient organizations and industry and realize precision medicine by effectively utilizing the rapidly advancing sequencing technologies to provide the highest standards of genomic testing in routine clinical care throughout Sweden. \n\n\n\nRegistration
URL:https://www.scilifelab.se/event/clinical-talks-the-road-towards-precision-medicine-in-sweden/
LOCATION:Online event via Zoom
CATEGORIES:Event
ATTACH;FMTTYPE=image/jpeg:https://www.scilifelab.se/wp-content/uploads/2021/09/ClinicalTalks_Season5_twitter_1024.jpg
ORGANIZER;CN="Clinical Talks":MAILTO:precisionmedicine@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20211130T103000
DTEND;TZID=Europe/Stockholm:20211201T150000
DTSTAMP:20260404T143105
CREATED:20210819T073949Z
LAST-MODIFIED:20211109T082852Z
UID:10000408-1638268200-1638370800@www.scilifelab.se
SUMMARY:Swedish Microfluidics in Life Science 2021
DESCRIPTION:The Swedish Microfluidics in Life Science meeting gathers researchers in the field of micro- and nanofluidics. The meeting offers an opportunity to present your research\, to network with researchers at Swedish universities\, institutes and companies \, and to listen to invited talks by a panel of well reputed research leaders. Confirmed speakers are Stefan Löfås (Innovido AB)\, Edith Hammer (Lund University)\, Christoph Merten (Ecole Polytechnique Fédérale de Lausanne)\, Anja Boisen (‎Technical University of Denmark) and Madhavi Krishnan (University of Oxford) \n\n\n\nSave the date and please help spread this information in your groups and local networks. \n\n\n\nRead more
URL:https://www.scilifelab.se/event/swedish-microfluidics-in-life-science-2021/
LOCATION:Lund University\, Lund\, Sweden
CATEGORIES:Event
ORGANIZER;CN="Swedish Microfluidics in Life Sciences":MAILTO:per.augustsson@bme.lth.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20211201T151500
DTEND;TZID=Europe/Stockholm:20211201T164500
DTSTAMP:20260404T143105
CREATED:20211104T130608Z
LAST-MODIFIED:20211119T151648Z
UID:10000481-1638371700-1638377100@www.scilifelab.se
SUMMARY:SciLifeLab COVID-19 seminars: Ralf Bartenschlager and Kristian Sandberg
DESCRIPTION:Topic: Drug screening and emerging viruses \n\n\n\nThe last of the five SciLifeLab COVID-19 seminars this autumn starts with Ralf Bartenschlager\, Professor\, Department of Infectious Diseases\, Molecular Virology\, Heidelberg University & Virus-associated Carcinogenesis\, German Cancer Research Center\, Heidelberg\, talking about Architecture and biogenesis of ER-derived viral replication organelles.Kristian Sandberg\, PhD\, Associate Professor.\, and SciLifeLab Drug Discovery and Development Platform Co-Director at Uppsala University\, then continues the seminar with his talk on Establishing a drug discovery platform for corona virus disease at SciLifeLab \n\n\n\nModerator: Marianna Tampere\, KI \n\n\n\n\n\n\n\n \n\n\n\n Registration is mandatory to get the Zoom link for the event  \n\n\n\n\nREGISTRATION\n\n\n\nBIOS & ABSTRACTS
URL:https://www.scilifelab.se/event/scilifelab-covid-19-seminars-ralf-bartenschlager-and-kristian-sandberg/
LOCATION:Online event via Zoom
CATEGORIES:Event
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20211203T100000
DTEND;TZID=Europe/Stockholm:20211203T150000
DTSTAMP:20260404T143105
CREATED:20211130T143531Z
LAST-MODIFIED:20211202T174958Z
UID:10000493-1638525600-1638543600@www.scilifelab.se
SUMMARY:MTLS Alumni Network Speaker Day
DESCRIPTION:The joint master’s programme in Molecular Techniques in Life Science fosters graduates for a professional research career in life science. It has a strong focus on molecular techniques for disease therapies and diagnostic tools\, coupled with substantial training in data analysis (bioinformatics and programming). The programme is a collaboration between Karolinska Institutet\, KTH and Stockholm University at the Science for Life Laboratory in Stockholm\, offering students the unique opportunity to study at all three institutions. \n\n\n\nFacts \n\n\n\nDate: Friday\, December 3rdTime: 10:00-15:00Location: Widerströmska Huset\, KI Campus Solna (Next to Scilifelab)\n\n\n\nWe are looking forward to welcoming alumni from Academia\, Industry\, and other science fields to this event\, where they will share their wisdom and experience with current students. \n\n\n\nAgenda:10:00-12:00 Session 112:00-13:00 Lunchbreak and Mingle13:00-15:00 Session 2 \n\n\n\nWe will announce the speaker list closer to the event. \n\n\n\n \n\n\n\nLearn more about the master’s programme here.
URL:https://www.scilifelab.se/event/mtls-alumni-network-speaker-day/
LOCATION:Widerströmska Huset\, Tomtebodavägen 18\, Solna\, Sweden
CATEGORIES:Event
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20211206T163000
DTEND;TZID=Europe/Stockholm:20211208T183000
DTSTAMP:20260404T143105
CREATED:20211201T120144Z
LAST-MODIFIED:20220104T121710Z
UID:10000494-1638808200-1638988200@www.scilifelab.se
SUMMARY:DDLS fellow candidates' seminars at Linköping University
DESCRIPTION:Welcome to listen to the seminars and discussions of the candidates for DDLS fellow position in I) Cell and Molecular Biology and in II) Precision Medicine and Diagnostics at Linköping University. The SciLifeLab and Wallenberg National Program for Data-Driven Life Science (DDLS) is a 12-year initiative funded with a total of 3.1 billion SEK from the KAW. \n\n\n\nRead more
URL:https://www.scilifelab.se/event/ddls-fellow-position-in-cell-and-molecular-biology-and-in-precision-medicine-and-diagnostics/
LOCATION:Online event via Zoom
CATEGORIES:Event
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20211207T090000
DTEND;TZID=Europe/Stockholm:20211207T110000
DTSTAMP:20260404T143105
CREATED:20210902T061020Z
LAST-MODIFIED:20211005T085331Z
UID:10000426-1638867600-1638874800@www.scilifelab.se
SUMMARY:BioImage Informatics Call4Help
DESCRIPTION:Every 1st week of the month (mainly on Tuesdays\, but there might be exceptions) the BioImage Informatics Facility together with microscopy expert Sylvie Le Guyader (LCI\, Karolinska Institutet) organizes a Call4Help session. The aim is to offer combined expertise towards microscopy and bioimage analysis. All researchers from Swedish institutes can participate. \n\n\n\nThe ideal timepoint to join the Call4Help session is when a researcher has performed pilot experiments and has tried out first analysis approaches – but before having recorded hundreds of images. Combining BIIF’s expertise in BioImage Analysis with microscopy expertise we can discuss ways to record the images that allow analysis afterwards. We will discuss different analysis approaches using mainly open-source software (Fiji\, CellProfiler\, QuPath\, Ilastik\, KNIME)\, but also commercial systems\, if needed (Imaris). \n\n\n\nThe Call4Help session format has been introduced to the BioImage Analysis community by NEUBIAS and ScopeM. \n\n\n\nHow to participate? \n\n\n\nWe prefer if you prepare a short presentation and upload it together with some example images according to the steps 1 and 2 below. This makes it easier for us when we have to prioritize between projects and allows us to prepare for the meeting. But if time permits\, we can also accept participants without this info. \n\n\n\nStep1: \n\n\n\nPrepare a short presentation (5-7 min)  – use the following template for your presentation: \n\n\n\nhttp://bit.ly/BIIF_C4H_slideTemplate \n\n\n\nSlide template by NEUBIAS/ScopeM \n\n\n\nStep2: \n\n\n\na) Upload your presentation \n\n\n\nUpload your presentation to a drive of your choice. You can also use our Call4Help google drive. Note that files shared on our Call4Help drive will be available to everyone until the session is over. \n\n\n\nhttp://bit.ly/BIIF_C4H_Drive \n\n\n\nb) Upload example images for testing. \n\n\n\nUpload example images for testing either to the drive of your choice or our Call4Help google drive above. \n\n\n\nhttp://bit.ly/BIIF_C4H_Drive \n\n\n\n \n\n\n\nc) Register by filling out the registration form: \n\n\n\nhttp://bit.ly/BIIF_C4H_Registration \n\n\n\nStep 3: \n\n\n\nJoin the zoom-session. \n\n\n\nIf your problem is selected for presentation\, you will get a time-slot of 30 – 60 minutes within the session. \n\n\n\nWhat are the Deadlines \n\n\n\nSubmission of a problem and upload of example data: Friday the week before the session. \n\n\n\nNotification about participation: The day before the session. \n\n\n\nNext Call4Help session \n\n\n\nTuesday\, December 7\, 2021\, 9.00-12.00. Deadline for application: Friday\, December 3\, 2021.
URL:https://www.scilifelab.se/event/bioimage-informatics-call4help-6/
CATEGORIES:Event
ORGANIZER;CN="Bioimage Informatics Unit":MAILTO:biif@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20211207T130000
DTEND;TZID=Europe/Stockholm:20211207T150000
DTSTAMP:20260404T143105
CREATED:20211118T134208Z
LAST-MODIFIED:20211201T145409Z
UID:10000490-1638882000-1638889200@www.scilifelab.se
SUMMARY:Affinity proteomics Uppsala present a seminar about the latest developments of the in situ proximity ligation assay
DESCRIPTION:Topic: Navinci in Situ Proximity ligation assay\, new developments\, applications\, and user presentations. \n\n\n\nSciLifeLab Affinity Proteomics Uppsala offer full service of in situ proximity ligation assays (PLA) in fixed cells or tissue sections to image\, with enhanced specificity\, the presence of specific proteins\, interactions and/or post-translational modifications to e.g. characterise acts of protein signaling in tumor tissues\, or to evaluate effects of drug treatment. Our latest addition is the PLA technology offered by Navinci and we would like to present this technology together with research presentations by users in a hybrid event (in-person and online). After the event there will be time for questions and refreshments at Mötestorget in Navet. \n\n\n\nWelcome! \n\n\n\n \n\n\n\n\n\n\n\nRegister here\n\n\n\n\n\n\n\nAgenda\n\n\n\nSeminar 13:00 – 15:00\, SciLifeLab\, Trippelrummet and Zoom \n\n\n\n13:00 Welcome and introduction (Mikael Åberg\, SciLifeLab Affinity Proteomics and Robert Gunnarsson\, Navinci) \n\n\n\n13:15 Agata Zieba Wicher\, Navinci: Introduction to Navinci technology \n\n\n\n13:40 Amanda Lindberg\, Uppsala University: Detection of activated PDGFRb receptor in NSCLC using NaveniFlex combined with a TSA-based detection method  \n\n\n\n14:00 Nicolle Heinzl\, Oncolabs 14:00 Nicolle Heinzl\, Oncolabs: “p53 prions” – A new promising cancer biomarker meets a disruptive technology \n\n\n\n14:20 Johan Heldin\, Uppsala University: Differential impact of lipid raft depletion on platelet-derived growth factor (PDGF)-induced ERK1/2 MAP-kinase and AKT signaling \n\n\n\n14:40 Brian Perrino\, University of Nevada : TBD \n\n\n\n15:00 – 17:00 Mingle with bubbles and canapés and open house with a vernissage at Navinci\, SciLifeLab Navet\, Mötestorget/ Navinci facilities 
URL:https://www.scilifelab.se/event/navinci-scilifelab-collaboration-seminar-navinci-open-house-and-vernissage/
LOCATION:Navet\, SciLifeLab Uppsala\, SciLifeLab Uppsala\, BMC C11\, Husargatan 3\, Uppsala\, 75237\, Sweden
CATEGORIES:Event
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20211208T093000
DTEND;TZID=Europe/Stockholm:20211208T150000
DTSTAMP:20260404T143105
CREATED:20211103T133810Z
LAST-MODIFIED:20211208T062219Z
UID:10000479-1638955800-1638975600@www.scilifelab.se
SUMMARY:Symposium: Science & SciLifeLab Prize for Young Scientists
DESCRIPTION:SciLifeLab and AAAS/Science magazine have joined forces in creating the Science & SciLifeLab Prize for Young Scientists to promote young scientists early in their careers. The Prize is awarded annually to four recent Ph.D. graduates for outstanding life science research.  \n\n\n\nJoin us\, to celebrate the 2020 and 2021 winners of the Science & SciLifeLab Prize for Young Scientists at the Scientific Symposium\, December 8\, 09:30-15:00.  \n\n\n\nThe bus from Tomtebodavägen 23 to Humanistiska Teatern departs at 07:45 and from Uppsala to Solna at 15:15. \n\n\n\nHybrid event\n\n\n\nOn-site\, Humanistiska Teatern\, Uppsala: The Symposium will include the Prize winner’s presentations\, a keynote lecture\, lunch\, and coffee with the possibility to meet and mingle with the winners and your SciLifeLab colleagues. Many people are interested in meeting IRL again but the seats are limited (100p). Register today! First-comes first served! Please cancel if you can’t come so that the spot can be available for someone else. We have bus transportation from Tomtebodavägen 23 at 07:45. \n\n\n\nWe need you to register for the on-site event by November 30\, at the latest for catering reasons. The registration will be open until we reach the maximum participants (100p)\, but we cannot guarantee lunch or coffee after November 30. If you have questions\, please contact events@scilifelab.se. \n\n\n\nRegistration\n\n\n\nProgram\n\n\n\nRemote: The event will be broadcasted on the SciLifeLab YouTube channel. You don’t have to register for the YouTube broadcast. But if you do\, you will get a reminder and a direct link to the event. Don’t miss this scientific symposium where you will meet the 2020 and 2021 year´s laureates and hear about their award-winning research.  \n\n\n\n \n\n\n\nThe Prize is awarded in the following categories: \n\n\n\n\n\nCell and Molecular BiologyResearch in this category includes cellular and molecular processes at levels ranging from single molecule to single cell to tissue and organ systems.Genomics\, Proteomics and Systems BiologyResearch in this category focuses on genomics\, proteomics\, integrative omics and systems biology approaches to facilitate comprehensive understanding of living cells\, organisms and species.Ecology and EnvironmentResearch in this category encompasses interactions between organisms and their environment\, and how these processes are influenced by human activity.Molecular MedicineResearch in this category aims at building on the molecular understanding of disease in humans to develop preventive\, diagnostic and therapeutic approaches\, including individualized medicine.\n\n\n\n\n\n\n\n\n\nShort facts: \n\n\n\nDate: December 8\, 2021 \n\n\n\nTime: 09:30-15:00 \n\n\n\nVenue: Humanistiska teatern\, Engelska Parken\, Uppsala and streaming to SciLifeLab YouTube channel. \n\n\n\nRegistration deadline For lunch and coffee\, register by November 30\, at the latest. Limited seats on site\, unlimited participants online \n\n\n\n \n\n\n\nAbout the Prize\n\n\n\nScience/AAAS and SciLifeLab\, have joined forces in creating the Science & SciLifeLab Prize for Young Scientists. Both Science/AAAS and SciLifeLab recognize that global economic health is dependent upon a vibrant research community and we need to incent our best and brightest to continue in their chosen fields of research. Considering the difficult economic environment\, we feel it is important to provide extra encouragement to young scientists as they begin their scientific careers. Each year\, the grand prize winner will receive a prize of US$30\,000; each of the three category winners will receive US$10\,000. The grand prize winning essay will be published in Science and essays from the three category winners will be published online. The prize is jointly operated by Science and SciLifeLab and is generously sponsored by the Knut and Alice Wallenberg Foundation.  \n\n\n\nRead more about the prize here. \n\n\n\n\n\n\n\nWatch this video to hear from the 2020 Grand Prize Winner and Category Winners!\n\n\n\n\n\n\n\n\n\n\n\n\n\nAbout Science/AAAS\n\n\n\nThe American Association for the Advancement of Science (AAAS) is the world’s largest general scientific society\, and publisher of the journals\, Science\, Science Translational Medicine\, Science Signaling\, Science Advances\, Science Immunology\, and Science Robotics. AAAS was founded in 1848\, and includes some 254 affiliated societies and academies of science\, serving 10 million individuals. Science\, founded by Thomas Edison\, has the largest paid circulation of any peer-reviewed general science journal in the world\, with an estimated total readership of 570\,400. \n\n\n\nThe non-profit AAAS—www.aaas.org—is open to all and fulfills its mission to “advance science and serve society” through initiatives in science policy\, international programs\, science education\, and more. Science further participates in various efforts to provide free access for scientists in the world’s poorest countries. \n\n\n\nAbout SciLifeLab\n\n\n\nAs a national hub for molecular biosciences in Sweden\, SciLifeLab develops and maintains unique research infrastructure\, services and data resources for life science. SciLifeLab coordinates research communities in health and environmental science\, recruitment and training of young scientists\, and fosters collaboration with industry\, health care\, public research organizations and international partners. The overall aim of SciLifeLab is to facilitate cutting-edge\, multi-disciplinary life science research and promote its translation to the benefit of society. \n\n\n\nSciLifeLab is jointly operated by its four founder universities: KTH Royal Institute of Technology\, Karolinska Institutet\, Stockholm University and Uppsala University. About 200 research groups\, 1500 researchers and 40 national infrastructure units are associated with SciLifeLab. The two main research centers are located in Stockholm and Uppsala\, but national SciLifeLab units exist at all major Swedish universities.
URL:https://www.scilifelab.se/event/symposium-science-scilifelab-prize-for-young-scientists/
LOCATION:Humanities Theater\, Engelska parken\, Uppsala\, 75238\, Sweden
CATEGORIES:Event
ATTACH;FMTTYPE=image/jpeg:https://www.scilifelab.se/wp-content/uploads/2020/11/winner-photos-2020_270x170_prizepicture_black-scaled.jpg
ORGANIZER;CN="Science/AAAS and SciLifeLab":MAILTO:events@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20211208T140000
DTEND;TZID=Europe/Stockholm:20211208T150000
DTSTAMP:20260404T143105
CREATED:20211124T131507Z
LAST-MODIFIED:20211206T105940Z
UID:10000491-1638972000-1638975600@www.scilifelab.se
SUMMARY:SciLifeLab Drug Discovery Seminar & DDD Exit event: Thomas Helleday
DESCRIPTION:Pharmacological targeting of MTHFD2 suppresses acute myeloid leukemia by inducing thymidine depletion and replication stress\n\n\n\n\n\n\n\nProfessor Thomas Helleday\, Karolinska Institutet \n\n\n\nSciLifeLab Drug Discovery Seminars\, hosted by the DDD platform\, is a series of educational lectures about recent developments\, technologies\, and trends in drug discovery and development that aims to enlighten\, and spark a discussion\, within the Swedish drug discovery community. \n\n\n\nAbstract \n\n\n\nThe folate metabolism enzyme MTHFD2 is consistently overexpressed in cancer but its roles are not fully characterized and current candidate inhibitors have limited potency for clinical development. Here we demonstrate a role for MTHFD2 in DNA replication and genomic stability in cancer cells\, and present optimised potent and selective nanomolar MTHFD2 inhibitors (MTHFD2i); protein co-crystal structures demonstrated binding to the active site of MTHFD2 and target engagement and that works in vitro and in vivo. \n\n\n\nThe results demonstrate a functional link between MTHFD2-dependent cancer metabolism and replication stress that can be exploited therapeutically with this new class of inhibitors. The work\, done in collaboration with the SciLifeLab DDD platform\, is accepted in the journal Nature Cancer and is the base for the creation of a new company: One-carbon therapeutics AB.  \n\n\n\nregistration
URL:https://www.scilifelab.se/event/scilifelab-drug-discovery-seminar-ddd-exit-event/
LOCATION:Air&Fire\, SciLifeLab Stockholm\, Tomtebodavägen 23A\, Solna\, Sweden
CATEGORIES:Event
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20211209T090000
DTEND;TZID=Europe/Stockholm:20211209T160000
DTSTAMP:20260404T143105
CREATED:20211110T201313Z
LAST-MODIFIED:20211125T070823Z
UID:10000488-1639040400-1639065600@www.scilifelab.se
SUMMARY:FAIR principles in life science research practice 
DESCRIPTION:Location: Online via Zoom\n\n\n\nThis online workshop will showcase how to put the FAIR principles into practice and is specifically designed to cater to life science researchers at all career stages. It is organised by SciLifeLab Data Centre and NBIS and include international speakers\, presenters from the SciLifeLab community and optional hands-on exercises guided by experts from NBIS and SciLifeLab Data Centre.  \n\n\n\nThe workshop aims to highlight some of the strongest motivators for adopting the FAIR principles and demonstrate how to operationalise them in your projects’ data management practices. While the intended audience is the full spectrum of researchers from experienced principal investigators to early career PhDs the registration open to everyone involved in life science research. To serve participants with varying roles and priorities the day is divided into two companion sessions and you can sign up for one or both at your leisure. The morning session covers the principles and a selection of case studies on how to operationalise them. The afternoon session is based on practical exercises and will provide an opportunity to gain hands-on experience of making research data FAIR. \n\n\n\nThe overall issues that the sessions aim to address is the fact that an increasing number of policymakers and funders are expecting research projects to adopt the FAIR principles for scientific data management. While the acronym is composed of words that are commonly associated with assessing secondary data—that is that they are Findable\, Accessible\, Interoperable\, and Reusable—it might not be obvious how to prepare your data to be FAIR. \n\n\n\nAcceptance to this workshop is on a first come\, first served basis. Registration is required to receive the Zoom link. The afternoon session is limited to 20 participants. \n\n\n\nMorning session (09:00–12:00)\n\n\n\nInvited speakers include international experts on supporting research projects in adopting the FAIR principles and a selection of projects from the SciLifeLab community that illustrate aspects of putting FAIR in practice. \n\n\n\nErik Schultes – Lead FAIR Implementation at the GO FAIR Foundation and a member of the Leiden Center for Data Science.Rob Hooft – Technical Coordinator for the Dutch ELIXIR Node and Programme Manager Data Stewardship at the Dutch Techcentre for Life Sciences (DTL).\n\n\n\nAfternoon session (13:00-16:00)\n\n\n\nJoin the local data management experts from SciLifeLab’s national bioinformatics support platform (NBIS) and SciLifeLab Data Centre in guided\, hands-on exercises on data organisation\, reproducibility and good data management practices that you can apply in your own projects. \n\n\n\nRegister here\n\n\n\nView the full agenda here
URL:https://www.scilifelab.se/event/fair-principles-in-life-science-research-practice/
LOCATION:Online event via Zoom
CATEGORIES:Event
ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2020/09/cropped-SciLifeLab_symbol_green.png
ORGANIZER;CN="SciLifeLab Data Centre":MAILTO:datacentre@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20211209T133000
DTEND;TZID=Europe/Stockholm:20211209T143000
DTSTAMP:20260404T143105
CREATED:20211207T081725Z
LAST-MODIFIED:20211207T083446Z
UID:10000498-1639056600-1639060200@www.scilifelab.se
SUMMARY:Validating antibodies for research applications
DESCRIPTION:Will Howat\, Senior director of Antibody Validation and Characterization at Abcam \n\n\n\nAbstract\n\n\n\nValidation of antibodies for use in scientific research is a tricky and time-consuming process which can stifle scientific progress. During this seminar\, I will demonstrate why we need validation and the tools that are available to help. \n\n\n\nBiography\n\n\n\nWill Howat leads Abcam’s approach to product validation and technical quality globally as Senior Director of Antibody Validation & Characterization. Prior to joining Abcam in 2018\, he worked at AstraZeneca as Team Leader of its Molecular Pathology Group\, where his team developed biomarker assays for preclinical\, Phase 1 and Phase 2 clinical trials. Before that he was at the Cancer Research UK’s Cambridge Institute\, where he set up and ran the Histopathology/ISH core facility for 9 years. He has also worked at the Wellcome Sanger Institute on the Atlas of Protein Expression and was responsible for R & D within the Immunohistochemistry group. \n\n\n\nWill has a BSc (Hons) in Immunology & Pharmacology from the University of Strathclyde and a PhD in Pathology from the University of Southampton. His publications span key journals such as The Lancet\, Nature\, Science\, Nature Genetics\, American Journal of Pathology\, and the Journal of Pathology. \n\n\n\nHosts\n\n\n\nFabio Socciarelli MD\, Henrik J. Johansson PhD
URL:https://www.scilifelab.se/event/validating-antibodies-for-research-applications/
LOCATION:Online event via Zoom
CATEGORIES:Event
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20211213T090000
DTEND;TZID=Europe/Stockholm:20211214T153000
DTSTAMP:20260404T143105
CREATED:20211104T100412Z
LAST-MODIFIED:20211210T140942Z
UID:10000480-1639386000-1639495800@www.scilifelab.se
SUMMARY:Cryo-EM 2021 user meeting  & Integrated Structural Biology user day
DESCRIPTION:The Integrated Structural Biology welcomes you to these two events. You can join either event – or both – and you can choose to participate online or on site in Air&Fire at SciLifeLab Campus Solna.  \n\n\n\nWe invite you to either or both of our events: \n\n\n\n3rd Cryo-EM Facility National Meeting – December 131st Integrated Structural Biology platform user meeting – December 14\n\n\n\n3rd Cryo-EM Facility National Meeting \n\n\n\nWelcome to join this meeting with users to discuss results and needs from the community. \n\n\n\nProgram – December 13 \n\n\n\n9.00News from the Cryo-EM facility nodes in Stockholm and Umeå10.00Fika10.20PReSTO for Cryo-EM\, Torben Rasmussen\, Linköping10.40Chameleon sample preparation for cryo-EM\,Sacha de Carlo\, SPT Labtech11:00Recent advances in the field of CryoEM Gaurav Sharma\, Thermo Fisher Scientific.11:20Structural proteomics for studying protein interactions and dynamicsSimon Ekström\, Lund University11:40Big and dynamic – An ancient and universal NMP kinaseTobias Sparrman12:00Lunch13:00Cryo-EM user discussion\, previous in-person meeting (drop-in service\, booking system\, cryoScreeeNET) and sensing the interest for potentiating new applications (electron diffraction\, FIB cryoET\, cryo-CLEM)15:00Wrap-up16:00End of Meeting\n\n\n\nRegister to attend this event\n\n\n\n\n\n\n\n1st Integrated Structural Biology platform user meeting \n\n\n\nThe purpose of this meeting is to show complementary techniques available at SciLifeLab Infrastructure and to encourage interactions. \n\n\n\nProgram – December 14 \n\n\n\n8:45General introduction to ISB platform9.00Presentation of Protein Production Sweden (PPS)Malin Bäckström9.15MicroED for structure determination of biomolecules\,  Laura Pacoste\, SU9.35NMR studies on VIM-2\, Hermina Wieske\, Uppsala University9.55Proteome-wide crosslinking mass spectrometry of host-pathogen interactions\, Lotta Happonen\, Lund University10.15Coffee Break11.00Structure and dynamics of the chromatin remodeler ALC1 bound to a PARylated nucleosome\, Luka Bacic\, Uppsala University11.20Structural basis of DegP-protease temperature-dependent activation\, Darius Šulskis\, University of Gothenburg11.40The interface study of M1-protein and M1-specific IgG via structural mass spectrometry\, TX-MS and HDX-MS\, Di Tang\, Lund University12.00Lunch13.00Cryo-EM structural study of the P5-type ATPases” Ping Li\, Kopenhagen University\, LU13.20Characterizing proteins in their native environment: Advances in in situ NMR\, Johannes Thoma\, University of Gothenburg13.40Unravelling the molecular basis of cell protection by Bcl-2 proteins\, Gerhard Gröbner\, Umeå University14.00Bruker on UF-MAS and structural biology14.30Discussion – user feed back15.20Final notes15:30End of Day\n\n\n\nRegister to attend this event
URL:https://www.scilifelab.se/event/cryo-em-and-isb-day-2021/
LOCATION:Air&Fire\, SciLifeLab Stockholm\, Tomtebodavägen 23A\, Solna\, Sweden
CATEGORIES:Event
ORGANIZER;CN="Integrated Structural Biology Platform at SciLifeLab":MAILTO:cecilia.persson@nmr.gu.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20211213T150000
DTEND;TZID=Europe/Stockholm:20211213T160000
DTSTAMP:20260404T143105
CREATED:20211209T160326Z
LAST-MODIFIED:20220330T154146Z
UID:10000500-1639407600-1639411200@www.scilifelab.se
SUMMARY:RNA Medicine\, the Next Frontier: Therapeutic Targeting of Non-Coding RNAs
DESCRIPTION:Anders NäärDepartment of Nutritional Sciences & Toxicology\, University of California\, Berkeley  \n\n\n\nBiography/Talk content\n\n\n\n\n\n\n\nAnders M. Näär is a Professor of Metabolic Biology in the Department of Nutritional Sciences & Toxicology at the University of California\, Berkeley. He was a postdoctoral research fellow with Robert Tjian at UC Berkeley/HHMI\, where he discovered the human Mediator transcriptional co-activator complex. Dr. Näär was a Professor in the Department of Cell Biology\, Harvard Medical School and the Massachusetts General Hospital Cancer Center. A major focus of his lab is to understand transcriptional and microRNA regulatory mechanisms controlling metabolic homeostasis to guide novel therapeutic strategies for the treatment of cardiovascular disease\, obesity\, Type 2 diabetes\, non-alcoholic fatty liver diseases (NAFLD/NASH)\, age-related macular degeneration (AMD)\, Duchenne muscular dystrophy (DMD)\, multi-drug resistant fungal infections\, and numerous types of cancer. His work resulted in a number of impactful studies\, patents and foundation of companies. In his talk\, Anders will broadcast his latest ventures in using RNA therapeutics in combating human diseases. \n\n\n\nDate: 13 December 2021Time: 3pm \n\n\n\nVenue (format hybrid): SciLifeLab\, lunchroom\, y2The ZOOM link is: https://ki-se.zoom.us/j/68353175106?pwd=bHZVYjFTMDR2YTN2ZzU1Nzk4eUZWdz09 \n\n\n\nMeeting ID: 683 5317 5106Passcode: 306128
URL:https://www.scilifelab.se/event/rna-medicine-the-next-frontier-therapeutic-targeting-of-non-coding-rnas/
LOCATION:Gamma 2 Lunchroom\, SciLifeLab\, Tomtebodavägen 23\, Solna\, Sweden
CATEGORIES:Event
ORGANIZER;CN="SciLifeLab Event":MAILTO:events@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20211215T130000
DTEND;TZID=Europe/Stockholm:20211215T170000
DTSTAMP:20260404T143105
CREATED:20211019T142541Z
LAST-MODIFIED:20211215T092421Z
UID:10000470-1639573200-1639587600@www.scilifelab.se
SUMMARY:Symposium on the ABC study: Biomarkers of Clinical Relevance – The ABC Risk Scores in Cardiovascular Diseases (CANCELLED)
DESCRIPTION:NOTE! Due to the current situation with the pandemic\, in combination with several of the invited speakers being ill\, this symposia has unfortunately been cancelled. The symposia will take place during the spring of 2022 and more details will come regarding a date and venue \n\n\n\n\n\n\n\nIn the ABC Risk Score project new tools for precision medicine in cardiovascular diseases have been developed. At this half-day symposium achievements obtained within the project will be presented and discussed. The ABC Risk Score project has been financed for 5 years by the Swedish Foundation for Strategic Research. \n\n\n\nThe symposium is free of charge\, including coffee and some light refreshments. For attending the coffee break and evening mingle\, please register by December 8. \n\n\n\nOrganizers\n\n\n\nAgneta Siegbahn: SciLifeLab\, Uppsala University\, department of Medical Sciences and Uppsala Clinical Research Center (UCR)  Lars Lind\, Jonas Oldgren and Lars Wallentin:  Uppsala University\, department of Medical Sciences and Uppsala Clinical Research Center (UCR) \n\n\n\n\n\n\n\n\nREGISTRATION\n\n\n\nPROGRAM
URL:https://www.scilifelab.se/event/symposium-on-the-abc-study-biomarkers-of-clinical-relevance-the-abc-risk-scores-in-cardiovascular-diseases/
LOCATION:Fåhræussalen\, Rudbecklaboratoriet\, Dag Hammarskjölds väg 20\, Uppsala\, -\, Sweden
CATEGORIES:Event
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220110T091500
DTEND;TZID=Europe/Stockholm:20220110T120000
DTSTAMP:20260404T143105
CREATED:20220104T120442Z
LAST-MODIFIED:20220104T124039Z
UID:10000503-1641806100-1641816000@www.scilifelab.se
SUMMARY:Data Driven Life Science Seminars at Gothenburg University - Precision medicine and diagnostics
DESCRIPTION:Welcome to attend the first open\, digital seminar as part of the recruitment process given by the top candidates for the two group leader positions in data driven life science (DDLS) at University of Gothenburg. \n\n\n\nThe SciLifeLab and Wallenberg National Program for Data-Driven Life Science (DDLS) is a 12-year initiative funded with a total of 3.1 billion SEK from the KAW.  \n\n\n\n\n\n\n\nRead more about the Seminar
URL:https://www.scilifelab.se/event/data-driven-life-science-seminars-fellows-at-gothenburg-university-precision-medicine-and-diagnostics/
CATEGORIES:Event
ATTACH;FMTTYPE=image/jpeg:https://www.scilifelab.se/wp-content/uploads/2022/01/Bild1-e1641298402677.jpg
ORGANIZER;CN="Data-Driven Life Science @ SciLifeLab":MAILTO:ddls@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220113T100000
DTEND;TZID=Europe/Stockholm:20220113T121500
DTSTAMP:20260404T143105
CREATED:20220104T123540Z
LAST-MODIFIED:20220104T123818Z
UID:10000504-1642068000-1642076100@www.scilifelab.se
SUMMARY:Data Driven Life Science Seminars at Gothenburg University - Epidemiology and infection biology
DESCRIPTION:Welcome to attend the second open\, digital seminar as part of the recruitment process given by the top candidates for the two group leader positions in data-driven life science (DDLS) at University of Gothenburg. \n\n\n\nThe SciLifeLab and Wallenberg National Program for Data-Driven Life Science (DDLS) is a 12-year initiative funded with a total of 3.1 billion SEK from the KAW.  \n\n\n\n\n\n\n\nRead more about the Seminar
URL:https://www.scilifelab.se/event/data-driven-life-science-seminars-at-gothenburg-university-epidemiology-and-infection-biology/
CATEGORIES:Event
ATTACH;FMTTYPE=image/jpeg:https://www.scilifelab.se/wp-content/uploads/2022/01/Bild1-e1641298402677.jpg
ORGANIZER;CN="Data-Driven Life Science @ SciLifeLab":MAILTO:ddls@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220118T083000
DTEND;TZID=Europe/Stockholm:20220118T113000
DTSTAMP:20260404T143105
CREATED:20220110T151719Z
LAST-MODIFIED:20220112T123959Z
UID:10000505-1642494600-1642505400@www.scilifelab.se
SUMMARY:DDLS Fellow candidate seminar at Umeå University
DESCRIPTION:Adjacent to the recruitment process for a group leader position in Data-Driven Life Science (DDLS) in precision medicine and diagnostics at Umeå University\, the top candidates will present at a seminar.  \n\n\n\nThe seminar will be held on Zoom\, January 18 2022 08:30 – 11:30. \n\n\n\n \n\n\n\nRead more\n\n\n\n\n\n\n\n \n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\nRead more
URL:https://www.scilifelab.se/event/ddls-fellow-candidate-seminar-at-umea-university/
CATEGORIES:Event
ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2021/06/DDLS-landing-page-images.png
ORGANIZER;CN="Data-Driven Life Science @ SciLifeLab":MAILTO:ddls@scilifelab.se
LOCATION:https://www.scilifelab.se/event/ddls-fellow-candidate-seminar-at-umea-university/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220119T100000
DTEND;TZID=Europe/Stockholm:20220119T140000
DTSTAMP:20260404T143105
CREATED:20220113T114132Z
LAST-MODIFIED:20220113T120355Z
UID:10000506-1642586400-1642600800@www.scilifelab.se
SUMMARY:DDLS Fellow candidates seminar at the Swedish Museum of Natural History (NRM)
DESCRIPTION:The Swedish Museum of Natural History (NRM) is hiring a tenure-track researcher in Data-Driven Life Science (DDLS)\, within the field of biodiversity and evolution. \n\n\n\nThe research position is funded by the SciLifeLab and Wallenberg National Program for Data-Driven Life Science (DDLS)\, which is a 12-year initiative funded with a total of 3.1 billion SEK from the Knut and Alice Wallenberg Foundation (for more details\, see www.scilifelab.se/data-driven). The DDLS Fellows will be recruited as independent group leaders at the respective host institution\, and will have the opportunity to link up with other local research groups as well as the within the national DDLS programme. \n\n\n\nAs a part of the recruitment process\, the top-ranked candidates for the NRM position will give digital seminars that are open for the general public.  \n\n\n\n \n\n\n\nSchedule of presentations: \n\n\n\n10:00 Nicolas Dussex \n\n\n\n10:30 Michael Westbury \n\n\n\n11:00 Tom van der Valk \n\n\n\n11:30 Break \n\n\n\n13:00 Elin Videvall \n\n\n\n13:30 Benjamin Vernot \n\n\n\n \n\n\n\nOrganizers: NRM DDLS Recruitment Committee
URL:https://www.scilifelab.se/event/ddls-fellow-candidates-seminar-at-the-swedish-museum-of-natural-history-nrm/
LOCATION:Online event via Zoom
CATEGORIES:Event
END:VEVENT
END:VCALENDAR