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X-WR-CALDESC:Events for SciLifeLab
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DTSTART;TZID=Europe/Stockholm:20220907T140000
DTEND;TZID=Europe/Stockholm:20220907T150000
DTSTAMP:20260407T214910
CREATED:20220826T140811Z
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UID:10000654-1662559200-1662562800@www.scilifelab.se
SUMMARY:Single-cell and spatial atlases of the adult and developing human brain
DESCRIPTION:Recently\, we have generated single-cell atlases of the adult and developing human brain using a combination of single-cell RNA sequencing and spatial transcriptomics. In the adult\, we found an unexpectedly high diversity of neuronal types especially in the midbrain and hindbrain\, with conservatively more than 3000 distinct types. In the developing human brain\, we revealed highly refined trajectories of differentiation of cortical neurons. We further found that astrocytes and oligodendrocytes were regionally patterned\, and that these region-specific types persisted in the adult. These findings may provide a basis for the brain region-specific occurrence of pediatric brain tumors. \n\n\n\n– \n\n\n\nSpeaker\n\n\n\nSten LinnarssonResearch Division of Molecular Neurobiology\, Karolinska Institutet\, Stockholm\, Sweden  \n\n\n\nHuman Developmental Dell Atlas (HDCA) is the Swedish effort within the human cell atlas (HCA)\, one of the largest international scientific projects. The project aim is to create a comprehensive molecular atlas of human prenatal development at the molecular resolution using state-of-the-art multi-omic technologies such as single-cell RNA-seq\, Spatial Transcriptomics\, in situ sequencing in order to provide deeper insight into how variations and deviations contribute to health and disease. \n\n\n\nThe HDCA Seminar Series 2022 invites you to join us on a journey of early human organogenesis of several organs at the single-cell and spatial resolution. Seminars will be held at SciLifeLab Gamma building on Wednesdays at 14:00 or 15:00 and also via Zoom. After each seminar\, we will have up to 30 min round up discussions with the speaker on how you can contribute to the atlas! \n\n\n\naccess zoom meeting
URL:https://www.scilifelab.se/event/single-cell-and-spatial-atlases-of-the-adult-and-developing-human-brain/
LOCATION:Gamma 2 Lunchroom\, SciLifeLab\, Tomtebodavägen 23\, Solna\, Sweden
CATEGORIES:Event
ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2022/08/logo_hdca.png
ORGANIZER;CN="The Human Developmental Cell Atlas":MAILTO:hdca-sweden@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220908T080000
DTEND;TZID=Europe/Stockholm:20220908T120000
DTSTAMP:20260407T214910
CREATED:20220906T102938Z
LAST-MODIFIED:20220906T103014Z
UID:10000671-1662624000-1662638400@www.scilifelab.se
SUMMARY:SciLifeLab Symposium in Microscale Acoustofluidics for Life Sciences
DESCRIPTION:SciLifeLab Symposium in Microscale Acoustofluidics for Life Sciences\, Sept. 8th 2022Organizers: Martin Wiklund (KTH) and Thomas Laurell (Lund University) \n\n\n\nLocation: Scilifelab\, Air/Fire\, Gamma-2\, Tomtebodavägen 23\, Solna \n\n\n\nProgram\n\n\n\n \n\n\n\nSession 1 (Air/Fire) \n\n\n\n08:20-08:30 Opening by Martin Wiklund\, KTH-Biophysics \n\n\n\n08.30-08.45 Cecilia Magnusson\, Lund\, ”Acoustic label-free isolation of circulating tumor cells in metastatic prostate cancer” \n\n\n\n08.45-09.00 Megan Havers\, Lund\, ”Silica seed particles improves performance in acoustic nanoparticle trapping” \n\n\n\n09.00-09.15 Axel Broman\, Lund\, ”Acoustic trapping for isolation of extracellular vesicles” \n\n\n\n09.15-09.30 Björn Hammarström\, KTH\, ”Acoustic focusing of protein crystals for improved sample delivery in serial crystallography” \n\n\n\n09.30-09.45 Thierry Baasch\, Lund\, ”High-throughput acoustic particle separation” \n\n\n\n09.45-10.00 Wei Qiu\, Lund\, ”High-performance bulk-wave-acoustophoresis devices using side actuation” \n\n\n\n10.00-10.30 coffee break (lobby outside Air/Fire) \n\n\n\nSession 2 (Air/Fire) \n\n\n\n10.30-10.45 Po-yin Chen\, Lund\, ”Microfluidic droplet shooter as a sample injection interface for MS” \n\n\n\n10.45-11.00 Niklas Sandström\, KTH\, ”Microwells for live cell assays” \n\n\n\n11.00-11.15 Valentina Carannante\, KTH-KI\, ”Multiplexed high-content screening of drug and immune sensitivity in microwells” \n\n\n\n11.15-11.30 Karl Olofsson\, KTH\, ”Multicellular tumor diskoids: A solid tumor model optimized for imaging” \n\n\n\n11.30-11.45 Giovanni Marinaro\, Lund\, “Design of acoustically-controlled ultrasmall droplet ejection in a microfluidic chip”
URL:https://www.scilifelab.se/event/scilifelab-symposium-in-microscale-acoustofluidics-for-life-sciences-sept-8th-2022/
LOCATION:Air&Fire\, SciLifeLab Stockholm\, Tomtebodavägen 23A\, Solna\, Sweden
CATEGORIES:Event
ORGANIZER;CN="Martin Viklund":MAILTO:martin.wiklund@biox.kth.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220908T120000
DTEND;TZID=Europe/Stockholm:20220909T120000
DTSTAMP:20260407T214910
CREATED:20220616T150853Z
LAST-MODIFIED:20220915T092128Z
UID:10000626-1662638400-1662724800@www.scilifelab.se
SUMMARY:Data-Driven Evolution and Biodiversity Research
DESCRIPTION:Mini-symposium \n\n\n\nWelcome to the first mini-symposium in data-driven evolution and biodiversity research sponsored by the Data-Driven Life Science (DDLS) program! At the mini-symposium\, the first group of DDLS Fellows in evolution and biodiversity will present themselves and their research plans. There will be several inspiring keynote talks\, presentations of the Swedish infrastructure for data-driven research in evolution and biodiversity\, and discussions of the future of the DDLS program. \n\n\n\nJoin us for an inspiring lunch-to-lunch meeting\, and help shape the future of data-driven evolution and biodiversity research in Sweden! \n\n\n\n\n\n\n\nHybrid event\n\n\n\nParticipate on site: New venue! Europasalen\, Konferenscentrum Wallenberg\, Medicinaregatan 20A\, Gothenburg\, Sweden. \n\n\n\nParticipate online: Online participation info\, e.g\, zoom link will be sent out upon registration \n\n\n\n\n\n\n\nDownload the Program here (PDF)  \n\n\n\nRegistration\n\n\n\n\n\n\n\nShort program\n\n\n\nThursday\, September 8\n\n\n\n12:00Lunch13:00Symposium starts (first day)17:00End of first day19:00SYMPOSIUM DINNER at Koks\, Vasagatan 9\, GothenburgAttendance is optional and the cost is the participant’s responsibility.\n\n\n\nFriday\, September 9\n\n\n\n08:30Symposium starts (second day)12:00Lunch\, end of the symposium\n\n\n\n\n\nPractical information\n\n\n\nIT support and adaptors will be available for presentersDeadline for onsite registration is August 29 (due to catering). Zoom registrations can be done until the event starts day 2.Lodging for September 8th is the attendee’s responsibility\, and there are many different kinds of options nearby the site. The speakers are booked at Hotel Poseidon.
URL:https://www.scilifelab.se/event/data-driven-evolution-and-biodiversity-research/
LOCATION:Europasalen\, Konferenscentrum Wallenberg\, Gothenburg\, Medicinaregatan 20\, Göteborg\, 413 90\, Sweden
CATEGORIES:Event
ATTACH;FMTTYPE=image/jpeg:https://www.scilifelab.se/wp-content/uploads/2022/06/AdobeStock_280363678-scaled.jpeg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220912T160000
DTEND;TZID=Europe/Stockholm:20220912T170000
DTSTAMP:20260407T214910
CREATED:20220905T092433Z
LAST-MODIFIED:20220914T005440Z
UID:10000669-1662998400-1663002000@www.scilifelab.se
SUMMARY:Clinical (phospho)-proteomics for precision medicine
DESCRIPTION:Clinical (phospho)proteomics for precision medicine \n\n\n\nWelcome to a lecture by Professor Connie R Jimenez\, Amsterdam University Medical Center\, Netherlands \n\n\n\n16.00-17.00 Monday September 12Air & Fire (Gamma 2) or via zoom https://kth-se.zoom.us/s/69393882589\n\n\n\n\n\n\n\nConnie Jimenez is Professor of Translational OncoProteomics at the Amsterdam University Medical Center in The Netherlands\, where she is heading the OncoProteomics Laboratory as well as the Proteomics Core Facility. \n\n\n\nShe is a molecular/cellular biologist with focus on the global analysis of the functional building blocks of life\, i.e.\, the proteins which activity and functions are highly deranged in disease. Her lab’s mission is to apply innovative mass spectrometry-based proteomics and data analysis to obtain systems biology insights into disease and to improve early diagnostics and treatment\, most notably of cancer and neurodegenerative disease. \n\n\n\nDuring her graduate studies at the Vrije Universiteit in Amsterdam (1993-1997)\, she pioneered single cell peptide profiling by mass spectrometry. During her post-doc in the Burlingame lab at UCSF\, San Francisco ((1997-1999)\, she applied proteomics to study neuron differentiation. In 2006\, she founded the OncoProteomics Laboratory (www.oncoproteomics.nl) with a start-up grant of the Cancer Center Amsterdam. \n\n\n\nTo date\, Dr. Jimenez (co)authored > 200 scientific peer reviewed articles. Underscoring her (inter)national esteem\, she founded the Netherlands Proteomics Platform in 2000 and is member of its steering board; she is general council member of the European Proteomics Association since 2005 and elected Vice-President since 2021; she is member of the steering committee of the Cancer HPP project of the Human Proteome Organisation. Finally\, she is editorial board member of several leading proteomics journals. \n\n\n\nThis keynote lecture is part of the FEBS Advanced Course – Exploring the Human Proteome
URL:https://www.scilifelab.se/event/clinical-phosphoproteomics-for-precision-medicine/
LOCATION:Air&Fire\, SciLifeLab Stockholm\, Tomtebodavägen 23A\, Solna\, Sweden
CATEGORIES:Event
ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2022/04/FEBS-Advanced-course.png
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220913T130000
DTEND;TZID=Europe/Stockholm:20220913T150000
DTSTAMP:20260407T214910
CREATED:20220622T110134Z
LAST-MODIFIED:20220912T074601Z
UID:10000635-1663074000-1663081200@www.scilifelab.se
SUMMARY:Spatial and Single Cell Biology Webinar
DESCRIPTION:The Spatial and Single Cell Biology Platform at SciLifeLab invites you to a virtual event where you can learn about the service we provide within the field of spatial and single cell omics. Take the opportunity to learn about cutting edge methods including spatial transcriptomics with Visium\, in situ sequencing\, spatial proteomics using highly multiplexed imaging\, spatial metabolomics with MALDI imaging and advanced FISH technologies. The presentations will be given by our experts in there respective methods\, working within the platform.  \n\n\n\nThe event is open for anyone to attend\, who are interested in including spatial omics in their research projects or with a general interest to learn about the methods. \n\n\n\nregister here\n\n\n\n\n\n\n\nProgram\n\n\n\n13:00 Short introduction to the Spatial and Single Cell Biology platform13:10 Single cell sequencing  Anja Mezger13:25Spatial Transcriptomics  Xesus Abalo13:40In situ sequencing  Chika Yokota13:55Spatial Proteomics (multiplexed IF) Charlotte Stadler14:10Advanced FISH Technologies Quentin Verron14:25Spatial Mass Spectrometry Anna Nilsson14:40Additional Q&A and end of webinar
URL:https://www.scilifelab.se/event/spatial-and-single-cell-biology-webinar/
LOCATION:Online event via Zoom
CATEGORIES:Event
ORGANIZER;CN="Spatial and Single Cell Biology Platform":MAILTO:charlotte.stadler@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220913T150000
DTEND;TZID=Europe/Stockholm:20220913T164500
DTSTAMP:20260407T214910
CREATED:20220630T181908Z
LAST-MODIFIED:20220818T095034Z
UID:10000639-1663081200-1663087500@www.scilifelab.se
SUMMARY:SciLifeLab Navet Open House
DESCRIPTION:Welcome to SciLifeLab Navet Open House on September 13 from 15:00 to learn more about SciLifeLab and the possibility to book meetings in Navet. Take the chance to network and talk science! \n\n\n\n\n\nSome of the activities:• General presentation of SciLifeLab 15:30\, E10:1309\, Jenny Alfredsson\, Acting Head of Operations• A Quiz tour as a walk around Navet’s meeting rooms 15:00 – 16:00. Price ceremony at 16:15• SciLifeLab poster exhibition• Mingle photographer on site• Relaxed networking with the opportunity to meet several SciLifeLab representatives on site \n\n\n\nIf SciLifeLab representatives want to participate in the poster exhibition\, please contact lokalbokning@SciLifeLab.uu.se. \n\n\n\n\n\n\n\nFor catering reasons\, please Register here
URL:https://www.scilifelab.se/event/scilifelab-navet-open-house/
LOCATION:Navet\, SciLifeLab Uppsala\, SciLifeLab Uppsala\, BMC C11\, Husargatan 3\, Uppsala\, 75237\, Sweden
CATEGORIES:Event
ATTACH;FMTTYPE=image/jpeg:https://www.scilifelab.se/wp-content/uploads/2022/06/Navet-fasad-innegård-scaled.jpg
ORGANIZER;CN="Operations office":MAILTO:events@SciLifeLab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220913T160000
DTEND;TZID=Europe/Stockholm:20220913T170000
DTSTAMP:20260407T214910
CREATED:20220905T092248Z
LAST-MODIFIED:20220914T005216Z
UID:10000668-1663084800-1663088400@www.scilifelab.se
SUMMARY:Mass spectrometry-based proteomics: technological advances and their application to plasma and single cell type resolved tissue proteo
DESCRIPTION:Mass spectrometry-based proteomics: technological advances and their application to plasma and single cell type resolved tissue proteomics \n\n\n\nWelcome to a lecture by Professor Matthias Mann\, Max Planck Institute\, Germany. \n\n\n\n16.00-17.00 Tuesday September 13Air & Fire (Gamma 2) or via zoom https://kth-se.zoom.us/s/69393882589\n\n\n\n\n\n\n\nMatthias Mann obtained his PhD in chemical engineering at Yale\, contributing to the Nobel Prize for his supervisor John Fenn for electrospray ionization. He is a director at the Max Planck Institute of Biochemistry\, Munich and also director of the Department of Proteomics\, Novo Nordisk Foundation Center for Protein Research at the University of Copenhagen. He has obtained numerous prizes and is one of the most cited scientists with an h-factor of 250 and 300\,000 total citations (Google Scholar). He has pioneered advances in sample preparation\, chromatography\, mass spectrometry and computer algorithms\, making mass spectrometry applicable to molecular biology. Apart from proteomics technology development\, the team works on biological questions in systems biology. Today\, the main focus is on clinically relevant topics\, especially the analysis of the blood plasma proteome and cancer tissues at the single-cell level. \n\n\n\nThis keynote lecture is part of the FEBS Advanced Course – Exploring the Human Proteome
URL:https://www.scilifelab.se/event/mass-spectrometry-based-proteomics-technological-advances-and-their-application-to-plasma-and-single-cell-type-resolved-tissue-proteo/
LOCATION:Air&Fire\, SciLifeLab Stockholm\, Tomtebodavägen 23A\, Solna\, Sweden
CATEGORIES:Event
ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2022/04/FEBS-Advanced-course.png
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220914T130000
DTEND;TZID=Europe/Stockholm:20220914T140000
DTSTAMP:20260407T214910
CREATED:20220905T091153Z
LAST-MODIFIED:20220906T122803Z
UID:10000666-1663160400-1663164000@www.scilifelab.se
SUMMARY:Mapping the development and regeneration of reproductive tissues
DESCRIPTION:Mapping the development and regeneration of reproductive tissues \n\n\n\nWelcome to a lecture by Roser Vento-Tormo\, Wellcome Sanger Institute\, UK. \n\n\n\n13.00-14.00 Wednesday September 14Air & Fire (Gamma 2) or via zoom https://kth-se.zoom.us/s/69393882589\n\n\n\n\n\n\n\nVento-Tormo’s research interest is to understand the influence of cellular microenvironments on individual cellular identities and responses\, in the context of development and immunity. Her team employs single-cell and spatial transcriptomics methods to deconstruct the cell signals in human organs and tissues\, and utilise this information to inform the reconstruction of novel in vitro models. Essential for this work\, is the novel computational tools her team develops to build cell–cell interactions networks from transcriptomics data. In her predoctoral research\, she studied the interplay between cell signalling and epigenetic machinery key to regulating cellular fate decisions in myeloid cells. She pursued her postdoctoral studies in the Teichmann laboratory as an EMBO / HFSP fellow\, where she developed CellPhoneDB.org\, a computational tool to study cell-cell communication from single-cell transcriptomics data. She used CellPhoneDB to disentangle the complex communication between maternal and fetal cells in the uterine-placental interface during early human pregnancy. Vento-Tormo work has been funded by many recognised international agencies (H2020\, MRC\, CZI\, Wellcome-LEAP)\, and she has recently obtained the Early Career Research Award from the Biochemistry Society (2021). \n\n\n\nThis keynote lecture is part of the FEBS Advanced Course – Exploring the Human Proteome
URL:https://www.scilifelab.se/event/mapping-the-development-and-regeneration-of-reproductive-tissues/
LOCATION:Air&Fire\, SciLifeLab Stockholm\, Tomtebodavägen 23A\, Solna\, Sweden
CATEGORIES:Event
ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2022/04/FEBS-Advanced-course.png
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220914T140000
DTEND;TZID=Europe/Stockholm:20220914T150000
DTSTAMP:20260407T214910
CREATED:20220905T092055Z
LAST-MODIFIED:20220906T122905Z
UID:10000667-1663164000-1663167600@www.scilifelab.se
SUMMARY:Systems Analysis of Human Metabolism for Identification of Drug Targets and Biomarkers
DESCRIPTION:Systems Analysis of Human Metabolism for Identification of Drug Targets and Biomarkers \n\n\n\nWelcome to a lecture by Professor Jens Nielsen\, \n\n\n\nBioinnovation Institute\, Copenhagen\, Denmark. \n\n\n\n \n\n\n\n \n\n\n\n\n\n\n\nJens Nielsen is MSc in Chemical Engineering and PhD (1989) in Biochemical Engineering from the Danish Technical University (DTU). Fulbright visiting professor at MIT in 1995-1996. Professor at DTU in 1998. In 2008 he was recruited as Professor to Chalmers University of Technology\, Sweden. In 2015 he was founding Head of the Department of Biology and Biological Engineering\, which now encompass more than 200 people. Jens Nielsen was also a co-founder of the Novo Nordisk Foundation Center for Biosustainability that now have more than 300 people affiliated\, for which he served as CSO 2013-2018. From 2019 CEO of the BioInnovation Institute in Denmark\, which is a new institute financed by USD0.5B that fosters translational research and support new spin-out companies in life sciences. He has trained more than 280 scientists in his research group and published >850 publications that have been cited more than 98\,000 times (current H-factor 142). Inventor of >50 patents and founder of seven biotech companies. Has received numerous awards\, including the ENI Award\, the Eric and Sheila Samson Prime Minister Prize for Transportation Fuels\, the Novozymes Prize\, and the Gold Medal from the Royal Swedish Academy of Engineering Sciences. Member of 12 academies\, including NAS\, NAE\, Chinese Academy of Engineering\, EMBO and Royal Swedish Academy of Science. He will discuss the challenges of using systems medicine for advancing the development of personalized and precision medicine\, and it will be illustrated how the concept of genome-scale metabolic models can be used for integrative analysis of big data with the objective of identifying novel biomarkers that are foundational for personalized and precision medicine. \n\n\n\nThis keynote lecture is part of the FEBS Advanced Course – Exploring the Human Proteome
URL:https://www.scilifelab.se/event/systems-analysis-of-human-metabolism-for-identification-of-drug-targets-and-biomarkers/
LOCATION:Air&Fire\, SciLifeLab Stockholm\, Tomtebodavägen 23A\, Solna\, Sweden
CATEGORIES:Event
ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2022/04/FEBS-Advanced-course.png
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220915T180000
DTEND;TZID=Europe/Stockholm:20220915T190000
DTSTAMP:20260407T214910
CREATED:20220906T122422Z
LAST-MODIFIED:20220906T122503Z
UID:10000672-1663264800-1663268400@www.scilifelab.se
SUMMARY:Molecular analysis of human diversity and its impact on drug discovery using iPS cells
DESCRIPTION:Molecular analysis of human diversity and its impact on drug discovery using iPS cells \n\n\n\n \n\n\n\nWelcome to a lecture by Professor Angus I. Lamond\, \n\n\n\nUniversity of Dundee\, UK. \n\n\n\n16.00-17.00 Thursday September 15 \n\n\n\nAir & Fire (Gamma 2) or via zoom https://kth-se.zoom.us/s/69393882589 \n\n\n\n\n\n\n\nProfessor Lamond has over thirty years of experience as a Principal Investigator\, studying molecular mechanisms regulating gene expression and pre-mRNA splicing. This includes major contributions to the biochemical analysis of the human splicing machinery and to the study of functional compartments and subnuclear bodies in mammalian cells. The AIL group have developed new methods and technical approaches in these fields that have advanced mechanistic studies at the molecular and cellular levels\, spanning biochemical\, microscopy and MS-based proteomics technologies. During the past fifteen years\, the AIL laboratory has developed and applied state of the art mass spectrometry-based proteomic approaches in research projects studying molecular mechanisms regulating gene expression in both human cells and model organisms. This includes\, specifically\, integrated poly-omics analyses of human induced pluripotent stem cells (hiPSCs)\, derived from both healthy donors and patient cohorts with inherited disorders. Other studies have focused on proteome dynamics in the context of biological response mechanisms and ongoing studies identifying and characterizing small molecule modulators of alternative splicing and analysis of how splicing mechanisms affect cell proteomes\, protein isoform expression and resulting cell phenotypes. He will describe the progress in using both quantitative\, MS-based proteomics and high throughput imaging technologies to characterize libraries of human induced pluripotent stem cell (iPSC) lines\, derived from hundreds of different donors\, and show how comparisons of such iPSC lines can provide a novel approach for assessing mechanisms of variable drug response and help to deliver more safe new drugs that cater for the needs of diverse human populations. \n\n\n\nThis keynote lecture is part of the FEBS Advanced Course – Exploring the Human Proteome
URL:https://www.scilifelab.se/event/molecular-analysis-of-human-diversity-and-its-impact-on-drug-discovery-using-ips-cells/
LOCATION:Air&Fire\, SciLifeLab Stockholm\, Tomtebodavägen 23A\, Solna\, Sweden
CATEGORIES:Event
ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2022/04/FEBS-Advanced-course.png
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220921T110000
DTEND;TZID=Europe/Stockholm:20220922T120000
DTSTAMP:20260407T214910
CREATED:20220825T104709Z
LAST-MODIFIED:20220902T094832Z
UID:10000653-1663758000-1663848000@www.scilifelab.se
SUMMARY:AIDA-SciLifeLab days
DESCRIPTION:Welcome to AIDA-SciLifeLab days in Uppsala\, September 21-22\n\n\n\nAnalytic Imaging Diagnostics Arena\, AIDA\, is a national arena for research and innovation around artificial intelligence\, AI\, for medical image analysis. Here\, academia\, healthcare and industry meet to translate technological advances in AI technology into patient benefits in the form of clinically useful tools. AIDA is an initiative within the Strategic Innovation Program Medtech4Health\, a joint venture of VINNOVA\, Formas and the Energy Agency. AIDA offers funding\, technical infrastructure and a broad expert community. The community meets in regular intervals at AIDA-days; seminar days with current medical imaging themes. \n\n\n\n\n\n\n\nThe AIDA days are on tour\, our first stop was Stockholm KTH\, and this time we are happy to visit Uppsala. SciLifeLab and Carolina Wählby are kindly hosting the event. We will now have the great opportunity to get an insight into the work on AI in medical imaging in Uppsala – focus areas and ongoing projects. We can look forward to presentations in quantitative microscopy\, image classification\, image registration and the European Big Picture project (a central repository for digital pathology slides). In addition\, we will listen to two final AIDA project presentations by the research groups of Robin Strand – MRI guided real-time adaptive radiotherapy and Joel Kullberg – Advanced Body Composition Analysis in SCAPIS. Each AIDAday will end with a study visit: at the radiology department (MR-Linac) and the pathology department\, respectively.  \n\n\n\n\n\n\n\nRegistration\n\n\n\n\n\n\n\nProgram September 21\n\n\n\nProgram September 22\n\n\n\n\n\n\n\nShort Program\n\n\n\n \n\n\n\n\n\nSEPT. 21:Venue: Nya Ångström\, lecture hall 101136 B (floor1)11:00Internal meeting for AIDA members only 12:00Lunch (recommendation “Rullan”\, Nya Ångström)13:00Official program17:00End of program19:00After Work at Stationen (optional)SEPT. 22:Venue: SciLifeLab Navet\, Trippelrummet\, BMC\, entrance C1109:00Official program12:00End of program\n\n\n\n\n\n\n\n\nLunch and AW at your own expense. \n\n\n\n\n\n\nFor those who are not able to attend the AIDAdays physically\, a Zoom link will be distributed to registered participants prior to the meeting. Please register here! \n\n\n\nMost Welcome!
URL:https://www.scilifelab.se/event/aida-scilifelab-days/
CATEGORIES:Event
ATTACH;FMTTYPE=image/jpeg:https://www.scilifelab.se/wp-content/uploads/2022/08/image001.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220926T090000
DTEND;TZID=Europe/Stockholm:20220926T100000
DTSTAMP:20260407T214910
CREATED:20220923T132853Z
LAST-MODIFIED:20220923T132926Z
UID:10000689-1664182800-1664186400@www.scilifelab.se
SUMMARY:Multiscale Modelling of Cancer Cell Motility and Tumour Evolution
DESCRIPTION:Paul Bates\, Cricks institute\, UK\n\n\n\n \n\n\n\n \n\n\n\n \n\n\n\nMultiscale Modelling of Cancer Cell Motility and Tumour Evolution \n\n\n\nSince Inhibiting metastasis is as crucial as minimising tumour growth for efficient treatment of cancer\, we constructed a multiscale model of cancer cell motility\, with our primary focus being on amoeboid type cell motility of metastasising tumour cells in the extracellular matrix (ECM).  Our model covered a wide parameter space and provided a deeper understanding of the conditions governing the motility of the cell at multiscale levels. Both the extracellular conditions (e.g. ECM density) and intrinsic cell properties (e.g. relative distribution of contractile and expanding regions of the cell membrane) were investigated.  The aim was to identify the combination of intrinsic properties metastasising cells are more likely to use under different extracellular conditions. After extensive benchmarking of the computational model using in vitro data\, we were able to predict cancer cell motility in vivo and under a number of different combinations of motility inhibitory\, such as key kinase inhibitors. We have also developed multiscale computer models to investigate how tumours evolve based upon Intra-tumour genetic heterogeneity (ITH)\, which fuels ongoing clonal evolution. Despite clarified clonal structure and acknowledged role of ITH in disease progression within our recent tumour study\, investigating clear-cell renal cell carcinomas (ccRCCs)\, there lacks characterisation of ongoing evolution that may inform future risk. By the combination of computer modelling and experimental analysis\, we investigated spatial features of narrow-scale clone diversity (microdiversity) and parallel evolution on the impact of spatial tumour growth. We observed frequent microdiversity hotspots and parallel evolution near the tumour margin and uncovered a scaling relationship between the area spanned by a genomic alteration and the number of subclones within that area\, in simulated tumours of 66 ccRCCs. Furthermore\, in-silico time-course studies showed that different modes of spatial growth caused varying extents and tempos of subclonal diversification.  Interestingly\, evolutionary trajectories were often predictable early\, suggesting that spatially resolved sampling combined with sequencing may enable identification of evolutionary potential in early-stage tumours.
URL:https://www.scilifelab.se/event/multiscale-modelling-of-cancer-cell-motility-and-tumour-evolution/
LOCATION:Air&Fire\, SciLifeLab Stockholm\, Tomtebodavägen 23A\, Solna\, Sweden
CATEGORIES:Event
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220927T100000
DTEND;TZID=Europe/Stockholm:20220927T113000
DTSTAMP:20260407T214910
CREATED:20220919T131401Z
LAST-MODIFIED:20220920T053525Z
UID:10000682-1664272800-1664278200@www.scilifelab.se
SUMMARY:Next-Generation Cytogenomics with Optical Genome Mapping
DESCRIPTION:Clinical Genomics Stockholm has acquired a Saphyr optical mapper from Bionano Genomics and it will be available as a national service. We would like to provide more information on the instrument and applications by giving a seminar. \n\n\n\nClick here to sign up\n\n\n\nFlyer\n\n\n\nFlyer_symposium_stockholm-1Download
URL:https://www.scilifelab.se/event/next-generation-cytogenomics-with-optical-genome-mapping/
LOCATION:Wangari\, Widerströmska building\,\, Tomtebodavägen 18\, Solna\, Sweden
CATEGORIES:Event
ORGANIZER;CN="Clinical Genomics Platform":MAILTO:marcela.davila@gu.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220928T090000
DTEND;TZID=Europe/Stockholm:20220928T150000
DTSTAMP:20260407T214910
CREATED:20220629T154628Z
LAST-MODIFIED:20220715T122018Z
UID:10000638-1664355600-1664377200@www.scilifelab.se
SUMMARY:SciLifeLab symposium in superresolution microscopy
DESCRIPTION:We cordially welcome you to a symposium teaching applications of superresolution fluorescence microscopy from world leading experts in the field.  \n\n\n\nRegistration to hans.blom@scilifelab.se \n\n\n\n \n\n\n\n\n\n\n\nProgram\n\n\n\n09:00OpeningDr Hans Blom – SciLifeLab\, Campus Solna09:05Superresolution microbiology using PALMProf Ulrike Endesfelder – University of Bonn\, Germany09:50The axonal architecture at the nanoscale revealed by STORMDr Christophe Leterrier – CNRS – Aix Marseille University\, FranceCoffee break11:00Characterization of organelle dynamics with live-cell STEDDr Giovanna Coceano – SciLifeLab\, Campus Solna11:45MINFLUX in practiceDr Daniel Jans – University Medical Center Göttingen\, GermanyPhD-students/Postdocs may also sign up for one-on-one project discussions with the experts (1:45 – 3:00 pm)
URL:https://www.scilifelab.se/event/scilifelab-symposium-in-superresolution-microscopy/
LOCATION:Air&Fire\, SciLifeLab Stockholm\, Tomtebodavägen 23A\, Solna\, Sweden
CATEGORIES:Event
ORGANIZER;CN="Advanced Light Microscopy Unit":MAILTO:stewen@kth.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220929T140000
DTEND;TZID=Europe/Stockholm:20220929T150000
DTSTAMP:20260407T214910
CREATED:20220913T160723Z
LAST-MODIFIED:20220913T161924Z
UID:10000681-1664460000-1664463600@www.scilifelab.se
SUMMARY:Context crosstalk of macrophages in cardiovascular disease
DESCRIPTION:Erik A.L. Biessen\, Maastricht University\, the Netherlands \n\n\n\n\n\n\n\n\n\n\nIn this paper\, Biessen et al. introduce a novel approach that integrates 15-plex multispectral immunofluorescent microscopy with mass spectrometry imaging to reveal murine atherosclerotic plaque myeloid heterogeneity. It maps the phenotypes’ tissue localization while allowing their further histological characterization and correlations with their cellular and molecular microenvironmental contexts. \nProf. Erik Biessen graduated in Biophysical Chemistry at Groningen University\, Netherlands (1985). He joined the Division of Biopharmaceutics of Leiden University (Prof. Dr. Th.J.C. Van Berkel) as a post-doctoral fellow and was selected for the prestigious Netherlands Heart Foundation (NHF) funded Molecular Cardiology Program to become Established Investigator in 2001. Dr. Biessen received an innovational research incentive premium of N.W.O in 2001 (VIDI/VICI precursor)\, acquired a second Established Investigatorship of the NHF in 2004\, and was appointed Professor in Therapeutic Gene Modulation at Leiden University in 2005. Since 2007 he is heading the Experimental Vascular Pathology group of CARIM (MUMC). Dr. Biessen has a part-time affiliation at the Institute for Molecular cardiovascular research of RWTH Aachen\, Germany since 2015. Dr. Biessen is/has been a board member of NHS-CVON ( 2010- 2013)\, Dutch Atherosclerosis Society (>2008)\, ZonMW TOP grant committee\, FWO Med6 Expert panel of FWO\, and Ph.D. assessment board of IWT (both Belgium). He is a scientific adviser of VantageView (St Louis\, USA)\, associate editor of Cardiovascular Research and Atherosclerosis\, and participates in several European research programs (e.g. ERA-CVD-AtheroMacHete\, 3 H2020 ITNs (Intricare\, Evolution\, CareSYAN)\, Interreg-EMR Healthy Ageing and EurLipids). Dr. Biessen aims for curiosity-driven cross-disciplinary research with an open eye for the valorization of findings. Through the years his focus has shifted from biophysical chemistry\, via medicinal chemistry and drug targeting to pathomechanistic studies of cardiovascular diseases (>2001)\, with a main emphasis on inflammation.
URL:https://www.scilifelab.se/event/context-crosstalk-of-macrophages-in-cardiovascular-disease/
LOCATION:Air&Fire\, SciLifeLab Stockholm\, Tomtebodavägen 23A\, Solna\, Sweden
CATEGORIES:Event
ORGANIZER;CN="SysMedicine":MAILTO:cheng.zhang@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220930T160000
DTEND;TZID=Europe/Stockholm:20220930T180000
DTSTAMP:20260407T214910
CREATED:20220829T074202Z
LAST-MODIFIED:20220912T073805Z
UID:10000655-1664553600-1664560800@www.scilifelab.se
SUMMARY:FAIRPoints-FAIR & Open Research 4Beginners
DESCRIPTION:Location: Online via Zoom \n\n\n\n\n\nFuture generations of scientists will benefit from early introduction of Open and FAIR principles. By providing a general understanding of sound\, open\, transparent\, and reproducible research principles and inspiring students we will gain a positive and real change in the academic culture ultimately leading to better research. \n\n\n\n\n\nIntroducing these concepts to the public can also help demystify the research process\, allay public fears about data misuse through inappropriate sharing\, and educate and inform the public about what it really means to work Openly and Reproducibly. \n\n\n\nIt can also be used to persuade the public to support ongoing efforts for Open and FAIR research in order to get the most out of taxpayer funds and garner more interest in participation in citizen science projects. \n\n\n\n \n\n\n\n\n\nWhat we want to do\n\n\n\nWe call for the inclusion of Open and FAIR principles at earlier time points e.g. in the school curriculum to young adults at school and undergraduate students. Together with Edinburgh ReproducibiliTea community we would like to develop training materials for that purpose. \n\n\n\nThe training material should encourage students to reflect on more general values such as transparency and openness in research\,  and motivate them to conduct methodologically sound research avoiding pitfalls associated with a lack of transparency and reproducibility. \n\n\n\nThis is a community led effort towards developing training material which is supported by the offer of a mentorship program provided by Open Life Science (OLS) to encourage individuals who might be interested in learning how to apply open principles in their work and in taking a leading role. \n\n\n\nHow to get involved\n\n\n\nThis is a first of a series of events designed to bring the community together to co-create material needed in different formats\, e.g. training slides\, guidebooks\, video/animations\, infographics etc… \n\n\n\nWe will facilitate the interactions via a series of community check-ins occurring between 4 to 6 weeks intervals\, we also offer biweekly co-working sessions and communications via slack for those who would like to stay in touch while working asynchronously. \n\n\n\nWe welcome all sorts of contributions e.g. input and suggestions\, reviewing\, spreading the word and advertising\, copy editing\, art work! You name it!!  \n\n\n\nJoin us at the kick-off to learn more about our plans and how you can contribute. \n\n\n\nRegister here\n\n\n\nSee event in your TimeZone \n\n\n\n\n\n\n\nAbout FAIRPoints\n\n\n\nFAIRPoints is an event series highlighting pragmatic measures developed by the community towards the implementation of the FAIR (Findable\, Accessible\, Interoperable\, Reusable) data principles\, in collaboration with GoFAIR US\, SDSC\, AGU\, and SciLifeLab Data Centre. \n\n\n\n \n\n\n\nSign up for future events here \n\n\n\nTwitter: @FAIR_Points
URL:https://www.scilifelab.se/event/fairpoints-fair-open-research-4beginners/
LOCATION:Online event via Zoom
CATEGORIES:Event
ORGANIZER;CN="SciLifeLab Data Centre":MAILTO:datacentre@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20221003T120000
DTEND;TZID=Europe/Stockholm:20221003T130000
DTSTAMP:20260407T214910
CREATED:20220919T163016Z
LAST-MODIFIED:20220919T163018Z
UID:10000684-1664798400-1664802000@www.scilifelab.se
SUMMARY:Vibrational Spectroscopy Core Facility - What’s in it for you?
DESCRIPTION:In the frame of the “SciLifeLab Site Umeå / KBC Infrastructure Seminar Series”\, the seminars will be organised every second Tuesday during autumn 2022\, in turn with IceLab Lunch Pitches. The seminars will be held in a hybrid format IRL in Glasburen\, KBC\, and online via Zoom. Take the chance to get information on facilities\, possibilities and services that infrastructure\, both SciLifeLab-associated and local\, can offer! Learn more about the seminar series and the schedule for autumn 2022 here. \n\n\n\nOn October 3rd\, 12:00-13:00\, you are welcome to participate in the seminar \n\n\n\nVibrational Spectroscopy Core Facility – What’s in it for you?\n\n\n\nby Andras Gorzsas\, ViSp facility manager and Senior research engineer at the Department of Chemistry \n\n\n\nSeminar description: The Vibrational Spectroscopy Core Facility provides in situ\, non-destructive\, label-free chemical compositional analysis in the form of FTIR and Raman spectroscopy and imaging. It is an open-access facility with many years of experience in a very broad spectrum of research areas\, from plant sciences and medicine to environmental and material sciences. \n\n\n\nJoin this lunch seminar to see some examples of what this facility can provide for your research\, ask questions and discuss possibilities. \n\n\n\nA tour to the instruments is available after the seminar for those interested. \n\n\n\nRegistration: To register your physical attendance and reserve your free sandwich\, please go to the registration Form \n\n\n\nRead more
URL:https://www.scilifelab.se/event/vibrational-spectroscopy-core-facility-whats-in-it-for-you/
LOCATION:Glasburen Seminar Room\, Chemical Biological Centre (KBC) Building\, Umeå University\, Umeå\, 901 87\, Sweden
CATEGORIES:Event
ORGANIZER;CN="SciLifeLab Ume%C3%A5":MAILTO:umea@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20221003T120000
DTEND;TZID=Europe/Stockholm:20221003T130000
DTSTAMP:20260407T214910
CREATED:20220927T093745Z
LAST-MODIFIED:20220927T102722Z
UID:10000692-1664798400-1664802000@www.scilifelab.se
SUMMARY:Meet the SciLifeLab Göteborg Site
DESCRIPTION:The SciLifeLab national site in Gothenburg\n\n\n\nMaria Smedh\, Site Coordinator\, SciLifeLab Göteborg \n\n\n\nAn overview of the national infrastructure SciLifeLab and the site in Gothenburg. \n\n\n\nSciLifeLab is a national infrastructure within life science with a wide range of advanced technology and expertise. The newly started SciLifeLab site in Gothenburg includes units at both the University of Gothenburg and Chalmers University of Technology and has a strongconnection to Sahlgrenska University Hospital. This seminar series is started with an overview of the site\, followed by presentations by the individual units. \n\n\n\nA light lunch will be offered during the talks for those joining on site. Online participation via Zoom is also available\, please click the zoom-link below to join the event at the appointed time. \n\n\n\nVenue\n\n\n\nAssembly Room Birgit Thilander\, Medicinaregatan 3
URL:https://www.scilifelab.se/event/meet-the-scilifelab-goteborg-site/
LOCATION:Birgit Thilander Lecture Hall\, Medicinaregatan 3\, Göteborg
CATEGORIES:Event
ORGANIZER;CN="SciLifeLab Gothenburg":MAILTO:gothenburg@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20221004T080000
DTEND;TZID=Europe/Stockholm:20221006T170000
DTSTAMP:20260407T214910
CREATED:20220831T141423Z
LAST-MODIFIED:20220912T074844Z
UID:10000662-1664870400-1665075600@www.scilifelab.se
SUMMARY:Swedish NMR meeting 2022
DESCRIPTION:The Swedish Nuclear Magnetic Resonance Spectroscopy (NMR) Meeting 2022 is held in Gothenburg between Oct 4 and 6\, hosted by the Swedish NMR Centre and the VR-funded SwedNMR network. \n\n\n\nRead more and register\n\n\n\nDeadlines:September 16 Registration for Poster Abstracts considered for oral presentationSeptember 28Registration for regular attendance \n\n\n\nRegistration fee and payment informationStudents & postdocs 1000 kr (1250 kr incl VAT)Academic 1500 kr (1875 kr incl VAT)Regular 2000 kr (2500 kr incl VAT)
URL:https://www.scilifelab.se/event/swedish-nmr-meeting-2022/
LOCATION:Conference Centre Wallenberg\, Medicinaregatan 20A\, Gothenburg\, 413 90\, Sweden
CATEGORIES:Event
ORGANIZER;CN="Swedish NMR Centre":MAILTO:info@nmr.gu.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20221007T090000
DTEND;TZID=Europe/Stockholm:20221007T093000
DTSTAMP:20260407T214910
CREATED:20220831T144618Z
LAST-MODIFIED:20220928T142055Z
UID:10000663-1665133200-1665135000@www.scilifelab.se
SUMMARY:[Clinical Talks] Implementing Precision Medicine from a global perspective
DESCRIPTION:Joanne M. Hackett\n\n\n\nHead of Genomic and Precision Medicine at IQVIA \n\n\n\n\n\n\n\nDr Hackett is a clinical academic\, entrepreneur\, investor\, and a strategic\, creative visionair with global experience spanning successful start-ups to Fortune 500 companies. Aside from her curious passion for life and positivity\, Joanne is known for building innovation\, driving personalised medicine and leading through fast paced\, complex changing ecosystems and integrations. Joanne’s goal is to contribute to bringing the world novel\, cost effective and simple health care solutions\, and she is particularly keen on building the case for prevention\, open science and citizen genomics. She has extensive global experience across academic\, business and clinical institutions\, and enjoys sharing her experiences with the Boards she sits on as well as companies she provides strategic advice to. \n\n\n\nJoanne has been publicly recognised for her relentless pursuit of revolutionising healthcare and has been named one of the top six Influential Leaders in Healthcare by CIO Look\, the Accenture Life Science Leader of the year\, Freshfields Top 100 Most Influential Women\, One HealthTech Top 70 Women in the NHS\, Pharmaceutical Market Europe’s 30 women leaders in UK healthcare and BioBeat Top 50 Women in Biotech Award. Joanne believes in human courage and perseverance against the odds\, and demonstrates that positive change\, whether in a company or in one’s personal life\, can be carved out from even the greatest of trials. As a believer of ‘health = wealth’\, Joanne is an internationally known yoga instructor. \n\n\n\nregister to receive zoom link\n\n\n\nModerator: Richard Rosenquist Brandell\, Genomic Medicine Sweden \n\n\n\nIQVIA Inc.\n\n\n\nIQVIA is a leading global provider of advanced analytics\, technology solutions\, and clinical research services to the life sciences industry. IQVIA creates intelligent connections across all aspects of healthcare through its analytics\, transformative technology\, big data resources and extensive domain expertise. IQVIA Connected Intelligence™ delivers powerful insights with speed and agility — enabling customers to accelerate the clinical development and commercialization of innovative medical treatments that improve healthcare outcomes for patients. With approximately 82\,000 employees\, IQVIA conducts operations in more than 100 countries. \n\n\n\nIQVIA is a global leader in protecting individual patient privacy. The company uses a wide variety of privacy-enhancing technologies and safeguards to protect individual privacy while generating and analyzing information on a scale that helps healthcare stakeholders identify disease patterns and correlate with the precise treatment path and therapy needed for better outcomes. IQVIA’s insights and execution capabilities help biotech\, medical device and pharmaceutical companies\, medical researchers\, government agencies\, payers and other healthcare stakeholders tap into a deeper understanding of diseases\, human behavior and scientific advances\, in an effort to advance their path toward cures. To learn more\, visit www.iqvia.com. \n\n\n\n \n\n\n\nClinical Talks\n\n\n\nClinical Talks is back for more! With a brand new and shiny Season 6. After successfully completing 5 seasons with > 70 enthusiastic Clinical Talkers to our record\, we have barely scratched the surface of all the amazing work our clinical\, academic and industry Life Science community has to offer. More about the upcoming events is available here. \n\n\n\nThese events are co-organized by Karolinska Institutet Innovations AB and SciLifeLab\, and brought to you by Colibri Ventures.
URL:https://www.scilifelab.se/event/clinical-talks-implementing-precision-medicine-from-a-global-perspective/
LOCATION:Online event via Zoom
CATEGORIES:Event
ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2022/08/Square-500x500-Clinical-Talks@4x.png
ORGANIZER;CN="Clinical Talks":MAILTO:precisionmedicine@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20221011T090000
DTEND;TZID=Europe/Stockholm:20221011T120000
DTSTAMP:20260407T214910
CREATED:20220920T161925Z
LAST-MODIFIED:20220927T123606Z
UID:10000686-1665478800-1665489600@www.scilifelab.se
SUMMARY:BioImage Analysis support – Call4Help
DESCRIPTION:Every month (mainly on Tuesdays\, but there might be exceptions) the BioImage Informatics Facility together with microscopy expert Sylvie Le Guyader (LCI\, Karolinska Institutet) organizes a Call4Help session. The aim is to offer combined expertise towards microscopy and bioimage analysis. All researchers from Swedish institutes can participate. \nThe ideal timepoint to join the Call4Help session is when a researcher has performed pilot experiments and has tried out first analysis approaches – but before having recorded hundreds of images. Combining BIIF’s expertise in BioImage Analysis with microscopy expertise we can discuss ways to record the images that allow analysis afterwards. We will discuss different analysis approaches using mainly open-source software (Fiji\, CellProfiler\, QuPath\, Ilastik\, KNIME)\, but also commercial systems\, if needed (Imaris). \nThe Call4Help session format has been introduced to the BioImage Analysis community by NEUBIAS and ScopeM. \n  \nHow to participate? \nStep1: \nPrepare a short presentation (5-7 min)  – use the following template for your presentation: \nhttp://bit.ly/BIIF_C4H_slideTemplate \nSlide template by NEUBIAS/ScopeM \nStep2: \n\na) Upload your presentation \n\n  \nUpload your presentation to a drive of your choice. You can also use our Call4Help google drive. Note that files shared on our Call4Help drive will be available to everyone until the session is over. \nhttp://bit.ly/BIIF_C4H_Drive \n\nb) Upload example images for testing. \n\nUpload example images for testing either to the drive of your choice or our Call4Help google drive above. \nhttp://bit.ly/BIIF_C4H_Drive \n\nc) Register by filling out the registration form: \n\nhttp://bit.ly/BIIF_C4H_Registration \nStep 3: \nJoin the zoom-session. \nIf your problem is selected for presentation\, you will get a time-slot of 30 – 60 minutes within the session. \n  \nWhat are the Deadlines \nSubmission of a problem and upload of example data: Friday the week before the session. \nNotification about participation: The day before the session. \nNext Call4Help session: Tuesday\, October 11\, 2022\, 9.00-12.00 \nDeadline for application: Friday\, October 7\, 2022
URL:https://www.scilifelab.se/event/bioimage-analysis-support-call4help-7/
LOCATION:Online event via Zoom
CATEGORIES:Event
ORGANIZER;CN="Bioimage Informatics Unit":MAILTO:biif@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20221011T120000
DTEND;TZID=Europe/Stockholm:20221011T130000
DTSTAMP:20260407T214910
CREATED:20220927T104040Z
LAST-MODIFIED:20220927T104229Z
UID:10000693-1665489600-1665493200@www.scilifelab.se
SUMMARY:Clinical Genomics Gothenburg - Infrastructure and Research services
DESCRIPTION:Clinical Genomics Gothenburg – Infrastructure and Research services\n\n\n\nMeena Kanduri\, Clinical Genomics\, SciLifeLab Göteborg \n\n\n\nJoin us to learn more about the NGS-based services and the bioinformatic support that we offer at Clinical Genomics Gothenburg (CGG) unit with a focus towards translational and clinical research. \n\n\n\nSciLifeLab is a national infrastructure within life science with a wide range of advanced technology and expertise. The newly started SciLifeLab site in Gothenburg includes units at both the University of Gothenburg and Chalmers University of Technology and has a strongconnection to Sahlgrenska University Hospital. This seminar series is started with an overview of the site\, followed by presentations by the individual units. \n\n\n\nA light lunch will be offered during the talks for those joining on site. Online participation via Zoom is also available\, please click the zoom-link below to join the event at the appointed time. \n\n\n\nVenue\n\n\n\nAssembly Room Birgit Thilander\, Medicinaregatan 3
URL:https://www.scilifelab.se/event/clinical-genomics-gothenburg-infrastructure-and-research-services/
LOCATION:Birgit Thilander Lecture Hall\, Medicinaregatan 3\, Göteborg
CATEGORIES:Event
ORGANIZER;CN="SciLifeLab Gothenburg":MAILTO:gothenburg@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20221013T150000
DTEND;TZID=Europe/Stockholm:20221013T160000
DTSTAMP:20260407T214910
CREATED:20221005T141602Z
LAST-MODIFIED:20221005T141605Z
UID:10000708-1665673200-1665676800@www.scilifelab.se
SUMMARY:Structural proteogenomics analyses of circulating antibody repertoires
DESCRIPTION:We showcase a novel structural proteogenomics workflow to decipher the properties of circulating antibody repertories relating to immunity against bacteria and viruses. \n\n\n\nProf. Johan Malmström\, Lund University \n\n\n\nOctober 13th\, 15:00-16:00 SciLifeLab Gamma-2 lunchroom
URL:https://www.scilifelab.se/event/structural-proteogenomics-analyses-of-circulating-antibody-repertoires/
LOCATION:Gamma 2 Lunchroom\, SciLifeLab\, Tomtebodavägen 23\, Solna\, Sweden
CATEGORIES:Event
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20221013T151500
DTEND;TZID=Europe/Stockholm:20221013T163000
DTSTAMP:20260407T214910
CREATED:20221005T112555Z
LAST-MODIFIED:20221005T113202Z
UID:10000707-1665674100-1665678600@www.scilifelab.se
SUMMARY:[The Svedberg seminar] Prof. Jay Hinton
DESCRIPTION:University of Liverpool\, UK \n\n\n\nTime: 15:15Venue: C8:305\, BMC\, Uppsala \n\n\n\nHost: Siv Andersson\, Uppsala University \n\n\n\nProf. Jay Hinton is Professor of Microbial Pathogenesis at the University of Liverpool. Prof. Prof. Hinton has developed RNA-seq-based approaches for studying gene expression of in vitro-grown and intra-macrophage bacteria. He is currently using functional genomics methods to understand how new Salmonella pathovariants are causing endemic bloodstream infections across sub-Saharan Africa. This disease has killed around 500\,000 people over the last decade. \n\n\n\nTitle of the talk: How has Salmonella become so dangerous in Africa?\n\n\n\nWith 3.4 million infections each year\, invasive non-Typhoidal Salmonella (iNTS) is a major cause of illness worldwide. In Sub-Saharan Africa\, bloodstream infections involving iNTS Salmonella enterica serovar Typhimurium are causing ~49\,000 deaths annually. Co-infection with HIV or malaria in adults\, and a young age (<5 years) are known risk factors. The main causative agent of iNTS is a pathovariant of Salmonella Typhimurium called ST313\, which is multi-drug resistant and closely-related to the ST19 type of Salmonella responsible for gastroenteritis globally. \n\n\n\nUsing a combination of comparative genomics and comparative transcriptomics\,we discovered phenotypic differences that distinguish African from global Salmonella pathovariants (Canals et al.\, 2019; Honeycutt et al.\, 2020). \n\n\n\nOur analysis led us to identify a single core genome SNP responsible for the up-regulation of a single promoter in strain D23580 that controlled the expression of a Salmonella virulence factor (Hammarlöf et al.\, 2018)\, and offers part of the explanation of the pan-African epidemic of bloodstream infection.All of the Salmonella transcriptomic data we have generated are now available online in a user-friendly website that allows intra-strain and inter-strain comparisons of gene expression between African and global pathovariants ofS. Typhimurium: https://tinyurl.com/SalComD23580 \n\n\n\nMost recently\, we used the combined power of genomics and epidemiology and thousands of historical and contemporary Salmonella isolates to understand the precise evolutionary trajectory of the S. Typhimurium ST313 pathogen in Africa. We identified a series of novel genome degradation events that impacted upon the function of Salmonella genes required for colonisation of the mammalian gut\, providing evidence of niche adaptation and the continuing evolution of ST313 (Pulford et al.\, 2021). \n\n\n\nI will summarise the evolutionary pathway of invasive S. Typhimurium across Africa\, and explain the value of an integrated functional genomic analysis for understanding how bacterial pathogens cause disease. \n\n\n\nReferencesCanals et al. (2019) Adding function to genome of African Salmonella Typhimurium ST313. PLoS Biology 17(1): e3000059. DOI: 10.1371/journal.pbio.3000059 \n\n\n\nHammarlöf et al. (2018) Role of a single noncoding nucleotide in the evolution of an epidemic African clade of Salmonella. PNAS 115: E2614 – E2623. \n\n\n\nDOI: 10.1073/pnas.1714718115 \n\n\n\nHoneycutt et al. Genetic variation in the MacAB-TolC efflux pump influences pathogenesis of invasive Salmonella isolates from Africa. PLoS Pathog. 2020 16:e1008763. DOI: 10.1371/journal.ppat.1008763 \n\n\n\nPulford et al. (2021) Stepwise evolution of Salmonella Typhimurium ST313 causing bloodstream infection in Africa. Nature Microbiology 6: 327–338. \n\n\n\nDOI:10.1038/s41564-020-00836-1
URL:https://www.scilifelab.se/event/the-svedberg-seminar-prof-jay-hinton/
CATEGORIES:Event
ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2022/02/Picture1-The-Svedberg.png
ORGANIZER;CN="The Svedberg Seminar Series":MAILTO:thesvedberg@scilifelab.uu.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20221014T153000
DTEND;TZID=Europe/Stockholm:20221014T170000
DTSTAMP:20260407T214910
CREATED:20221010T171937Z
LAST-MODIFIED:20221010T172151Z
UID:10000711-1665761400-1665766800@www.scilifelab.se
SUMMARY:The Dark Side of Science: Misconduct in Biomedical Research
DESCRIPTION:Researchers in all stages of their career are welcome to attend and could find the talk useful. Kindly feel free to extend the invitation to your home universities.  \n\n\n\nFlyer-BAM-Elisabeth-BikDownload\n\n\n\nScience builds upon science. Even after peer-review and publication\, science papers could still contain images or other data of concern. If not addressed post-publication\, papers containing incorrect or even falsified data could lead to wasted time and money spent by other researchers trying to reproduce those results. Several high-profile science misconduct cases have been described\, but many more cases remain undetected. Elisabeth Bik is an image forensics detective who left her paid job in industry to search for and report biomedical articles that contain errors or data of concern. She has done a systematic scan of 20\,000 papers in 40 journals and found that about 4% of these contained inappropriately duplicated images. In her talk she will present her work and show several types of inappropriately duplicated images and other examples of research misconduct. In addition\, she will show how to report scientific papers of concern\, and how journals and institutions handle such allegations. \n\n\n\nElisabeth Bik\, PhD is a Dutch-American microbiologist who has worked for 15 years at Stanford University and 2 years in industry. Since 2019\, she is a science integrity volunteer and consultant who scans the biomedical literature for images or other data of concern and has reported over 6\,000 scientific papers.  Her work has resulted in over 900 retracted and almost 1\,000 corrected papers.  \n\n\n\nWho the event is aimed at i.e.\, who will attend:  Researchers in all stages of their career are welcome to attend and could find the talk useful. Kindly feel free to extend the invitation to your home universities.  \n\n\n\nSpeakers: Dr. Elisabeth Bik
URL:https://www.scilifelab.se/event/the-dark-side-of-science-misconduct-in-biomedical-research/
LOCATION:Online event via Zoom
CATEGORIES:Event
ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2022/08/logo_PhD_Postdoc_Council.png
ORGANIZER;CN="SciLifeLab Solna PhD & Postdoc Council":MAILTO:phd-council@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20221017T151500
DTEND;TZID=Europe/Stockholm:20221017T161500
DTSTAMP:20260407T214910
CREATED:20221009T184510Z
LAST-MODIFIED:20221009T185208Z
UID:10000710-1666019700-1666023300@www.scilifelab.se
SUMMARY:[The Svedberg] - Manfred Schartl
DESCRIPTION:Developmental Biochemistry\, University of Würzburg\, Germany \n\n\n\nTime: 15:15Venue: C8:305\, BMC\, Uppsala \n\n\n\nHost: Leif Andersson\, Uppsala University \n\n\n\nTitle of the talk: Evolution of sex determination and sex chromosomes in fish \n\n\n\nBio: Prof. Manfred Schartl studied Biology and Chemistry at the University of Giessen\, Germany\, and graduated in Genetics. After postdoctoral research in Giessen and at the NIH in Bethesda he was team leader of a research group from 1985 to 1991 at the Gene Center of the Max Planck Institute for Biochemistry in Martinsried\, Germany. Until 2019 he was full professor and chairman of Physiological Chemistry at the Biocenter of the University of Würzburg. Currently\, he heads a research group as senior professor at the Biocenter and works as scholar in residence at the Xiphophorus Genetic Stock Center at Texas State University in San Marcos. He is member of the German Academy of Sciences\, Leopoldina\, and the European Academy of Sciences\, Academia Europea. He holds an honorary doctorate from the University of Bergen\, Norway.He uses the small aquarium fish biomedical models Xiphophorus and Medaka to understand molecular processes of organ development and their malfunction in disease with a focus on pigment cells and melanoma and another one on sex determination and gonad development. Key to his research is taking an evolutionary perspective to answer these questions on the basis of comparative genomics and molecular biology experimental studies. \n\n\n\nAbstract: Sex determination (SD) is unique biological process in showing an astonishing plasticity of mechanisms. Fish present the greatest variability of SD amongst vertebrates. In the case of genetic SD this is linked to a similarly high variability of sex chromosome differentiation. While in a handful of species with genetic SD the master SD genes have been identified\, their molecular function in directing the development of the bipotential gonad primordium towards testis or ovary is unclear in many cases or incompletely known in the others. To obtain a deeper understanding of this diversity we need a better knowledge of the molecular basis of SD mechanisms and the structure and genetic organization of sex chromosomes across a broad diversity of fish. To identify sex chromosomes and primary SD genes\, we use high throughput RAD-tag marker mapping\, transcriptomics\, Pool-Seq and whole genome sequencing to identify sex-specific chromosomal regions and candidate SD genes in sharks\, sturgeons and teleosts. This led to the identification of sex-specific markers\, allowing to delineate the extent of recombination suppression\, which turned out to be highly variable between species. We identified several species with clear cut XX/XY or ZZ/ZW monofactorial systems but also species with more complex sex-determination systems including species with a mix of genetic SD and environmental SD and species with potential polygenic systems. In species with available genomic resources\, sex-specific markers could be used to assign scaffolds to regions that are supposed to contain the primary SD gene. We identified candidate genes in several species and find that most of them belong to already known factors of the primary SD regulatory network including candidate genes that have not been found so far as being SD genes. We also find that many species harbor very poorly differentiated sex-chromosomes. The SD variety does not follow a phylogenetic pattern\, and turnovers of the genetic SD system from male to female heterogamety and vice versa are frequent in some groups\, making the evolutionary instability of SD a spectacular trait whose biological meaning is not yet understood.
URL:https://www.scilifelab.se/event/the-svedberg-manfred-schartl/
CATEGORIES:Event
ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2022/02/Picture1-The-Svedberg.png
ORGANIZER;CN="The Svedberg Seminar Series":MAILTO:thesvedberg@scilifelab.uu.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20221018T120000
DTEND;TZID=Europe/Stockholm:20221018T130000
DTSTAMP:20260407T214910
CREATED:20221011T110401Z
LAST-MODIFIED:20221011T110403Z
UID:10000712-1666094400-1666098000@www.scilifelab.se
SUMMARY:The Protein Expertise Platform - a Core Facility at the KBC and a node of PPS
DESCRIPTION:In the frame of the “SciLifeLab Site Umeå / KBC Infrastructure Seminar Series”\, the seminars will be organised every second Tuesday during autumn 2022. The seminars will be held in a hybrid format IRL in Glasburen\, KBC\, and online via Zoom. Take the chance to get information on facilities\, possibilities and services that infrastructure\, both SciLifeLab-associated and local\, can offer! Learn more about the seminar series and the schedule for autumn 2022 here: https://www.umu.se/en/research/infrastructure/medicinska-fakulteten/u/umea-centre-for-electron-microscopy-ucem/scilifelab-in-umea/scilifelab-site-umea–kbc-infrastructure-seminar-series/ \n\n\n\nOn October 18th\, 12:00-13:00\, you are welcome to participate in the seminar \n\n\n\nThe Protein Expertise Platform – a Core Facility at the KBC and a node of PPS \n\n\n\nby Uwe Sauer\, Associate professor\, PEP coordinator\, Department of Chemistry\, Umeå University \n\n\n\nRead more\n\n\n\nSeminar description: Proteins play a central role for most cellular processes. In order to study such processes\, Swedish Life-Science researchers rely on high-quality protein reagents for their research. At the Protein Expertise Platform (PEP) at the Dept. of Chemistry and the KBC\, we work with the custom production of recombinant proteins in E. coli and plant cell suspensions. We have teamed up with six other Swedish protein production platforms and\, since 2022\, are part of Protein Production Sweden (PPS)\, a national research infrastructure for protein production (www.gu.se/pps) funded by VR and the local Universities. PPS provides expert competence in a variety of expression systems\, including E. coli\, insect cells\, P. pastoris\, plant cells and cell-free translation. The PPS nodes collaborate in the form of a national distributed research infrastructure and provide expertise in gene and vector design\, production and purification of the proteins\, as well as methods for quality control. PPS can also produce proteins with different labels. \n\n\n\nResearchers can apply for project support through a common application portal found on the PPS website. \n\n\n\nRegistration: To register your physical attendance and reserve your free sandwich\, please go to the registration Link: https://www.umu.se/en/chemical-biological-centre/kbc_events/registration-form-infrastructure-seminar/ \n\n\n\nRegistration deadline: Monday\, 17 October\, 10:00. \n\n\n\nOnline attendance: You can also join the seminar on Zoom\, https://umu.zoom.us/j/63138997026 (registration is not required) \n\n\n\nMore information about PEP: https://www.umu.se/en/research/infrastructure/pep/ \n\n\n\nOrganisers: SciLifeLab Site Umeå and Chemical Biological Centre (KBC)
URL:https://www.scilifelab.se/event/the-protein-expertise-platform-a-core-facility-at-the-kbc-and-a-node-of-pps/
LOCATION:Glasburen Seminar Room\, Chemical Biological Centre (KBC) Building\, Umeå University\, Umeå\, 901 87\, Sweden
CATEGORIES:Event
ORGANIZER;CN="SciLifeLab Ume%C3%A5":MAILTO:umea@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20221020T093000
DTEND;TZID=Europe/Stockholm:20221020T163000
DTSTAMP:20260407T214910
CREATED:20220620T082646Z
LAST-MODIFIED:20221020T060635Z
UID:10000629-1666258200-1666283400@www.scilifelab.se
SUMMARY:The 8th RIKEN-KI-SciLifeLab Symposium
DESCRIPTION:Preparing for the next pandemic \n\n\n\n\n\nCOVID-19 pandemic responses were organized by countries according to their needs. The preparations for responses to potential future pandemics are currently addressed by organizations including RIKEN\, Karolinska Institutet and SciLifeLab with prominent roles in Japan and Sweden\, respectively. This symposium event\, which is part of the RIKEN-KI-SciLifeLab Symposium Series\, addresses the political\, organizational and practical aspects of preparedness for potentially upcoming pandemics with focus on Japan and Sweden.  \n\n\n\nThis symposium is co-organized and sponsored by JSPS Stockholm Office. \n\n\n\n\n\n\n\nDate and location 2022-10-20 (THU)  \n\n\n\n09:30-16:30 Symposium  \n\n\n\n16:30-18:00 Social mingle  \n\n\n\n \n\n\n\n\n\n\n\n\nDownload Program (PDF)\n\n\n\n\n\n\n\n\nRegistration\n\n\n\n\n\n\n\nSymposium history\n\n\n\nEach symposium of the series is centered on one specific topic. Topics from previous years are: Molecular Imaging and Genomics (2014)\, Structural Biology for Drug Discovery (2015)\, Decoding Health and Disease with a) Imaging & Disease\, b) RNA & Disease\, c) Single\, Rare and Stem cells & Disease (2016)\, Life Science Frontiers in Health\, Disease and Aging\, with sessions a) Gene Expression in Disease and Aging\, b) Neural Function\, Disease and Therapy\, c) Molecular Aspects of Health\, Disease and Aging\, d) Visualizing Health\, Disease and Aging\, e) Molecular Network Control (2017)\, Artificial Intelligence meet Life Sciences (2018)\, and Biomedical Data for Artificial Intelligence (2019\, 2020).
URL:https://www.scilifelab.se/event/the-8th-riken-ki-scilifelab-symposium/
LOCATION:Air&Fire\, SciLifeLab Stockholm\, Tomtebodavägen 23A\, Solna\, Sweden
CATEGORIES:Event
ATTACH;FMTTYPE=image/jpeg:https://www.scilifelab.se/wp-content/uploads/2022/06/IMG_6802.jpeg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20221021T090000
DTEND;TZID=Europe/Stockholm:20221021T093000
DTSTAMP:20260407T214910
CREATED:20220831T154039Z
LAST-MODIFIED:20220928T142401Z
UID:10000664-1666342800-1666344600@www.scilifelab.se
SUMMARY:[Clinical Talks] Stanford Ignite: Lessons learned from teaching entrepreneurs
DESCRIPTION:Yossi Feinberg\n\n\n\nThe Adams Distinguished Professor of Management and Professor of Economics at Stanford Graduate School of Business (GSB) \n\n\n\n\n\n\n\nYossi Feinberg received his PhD in Mathematics from the Hebrew University in Jerusalem in 1997. His thesis studied how differing prior beliefs of decision makers can be expressed by their disagreement on current (posterior) events. After completing his dissertation under the supervision of Nobel Laureate Professor Robert J. Aumann\, Yossi began teaching economics at Kellogg Graduate School of Management. Yossi joined Stanford GSB in 1998. \n\n\n\nYossi’s teaching interests include Economics of Organization\, Managerial Economics\, Strategy\, Information Markets\, Game Theory and Applied Decision Making. In 2003 he received the MBA distinguished teaching award. \n\n\n\nYossi’s recent research interests include\, for example\, the analysis and implication of strategic decision making in the face of unawareness. He has modeled games with unawareness and their solutions. In these games each decision maker can reason about the extent to which others may only have a limited perception of the full scale of the economic interaction at hand. Yossi was an Associate Editor of the Journal of Economic Theory and is serving as a referee for all major microeconomics journals. He has given numerous invited seminars as well as multiple plenary talks at academic conferences. \n\n\n\nHe has been consulting in a wide range of industries including hi-tech\, media and healthcare as well as giving invited talks on topics such as pricing\, the sub-prime crisis\, in-house vs. outsourcing\, allocating decision power in organizations and strategic interactions. \n\n\n\nHe is the faculty director of Stanford Ignite\, a global innovation program running on the Stanford Campus. \n\n\n\nregister to receive zoom link\n\n\n\nStanford Ignite\n\n\n\nStanford Ignite grew out of a new kind of entrepreneurial educational program initiated in 2006 and spearheaded by Professor Yossi Feinberg. In aggregate\, about 1\,600 past participants have started more than 100 successful companies since the program was introduced. \n\n\n\nStanford Ignite is a certificate program that provides the business fundamentals necessary to succeed at any entrepreneurial or intrapreneurial venture. Business concepts learned in the classroom span core business skills and functional skills\, and are reinforced through practical application with team venture projects\, where participants work by project-based learning approach\, in teams of five or six to develop a new product or service for an existing organization or a new venture.Previous participants include graduate students currently pursuing a master’s\, MD\, PhD\, or post-doc program in a nonbusiness field\, with a strong representation from the Life Sciences area. A key attribute to of the success of the program is the close academic experience it offers. Participants engage directly with the same renowned faculty that teach in the Stanford MBA Program. Participation in real-time lectures\, case evaluations\, Q&A sessions\, small group discussions\, workshops\, panels\, and team projects. The program also features guest speakers from leading companies\, many of whom become venture-project mentors. \n\n\n\nKey Benefits\n\n\n\nStanford Ignite –is a certificate program that provides the business fundamentals to succeed at any entrepreneurial ventures. \n\n\n\nLearn fundamental business concepts from core business frameworks to tactical skills.Reinforce and apply lessons learned by working on a team to develop a new product or service.Improve communication\, elevator pitch\, and presentation skills in a daylong communications bootcamp.Present your idea and get robust feedback from venture capitalists\, angel investors\, industry experts\, and experienced entrepreneurs.\n\n\n\n \n\n\n\nClinical Talks\n\n\n\nClinical Talks is back for more! With a brand new and shiny Season 6. After successfully completing 5 seasons with > 70 enthusiastic Clinical Talkers to our record\, we have barely scratched the surface of all the amazing work our clinical\, academic and industry Life Science community has to offer. More about the upcoming events is available here. \n\n\n\nThese events are co-organized by Karolinska Institutet Innovations AB and SciLifeLab\, and brought to you by Colibri Ventures.
URL:https://www.scilifelab.se/event/clinical-talks-yossi-feinberg/
LOCATION:Online event via Zoom
CATEGORIES:Event
ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2022/08/Square-500x500-Clinical-Talks@4x.png
ORGANIZER;CN="Clinical Talks":MAILTO:precisionmedicine@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20221021T110000
DTEND;TZID=Europe/Stockholm:20221021T120000
DTSTAMP:20260407T214910
CREATED:20221004T164130Z
LAST-MODIFIED:20221004T164133Z
UID:10000706-1666350000-1666353600@www.scilifelab.se
SUMMARY:3D-Equivariant Graph Neural Networks for Refining and Evaluating Protein Structures
DESCRIPTION:Speaker: \n\n\n\nJianlin Cheng\, Department of Electrical Engineering and Computer Science at the University of Missouri\, Columbia\, USA. \n\n\n\nTitle3D-Equivariant Graph Neural Networks for Refining and Evaluating Protein Structures \n\n\n\nAbstract \n\n\n\nDeep learning is revolutionizing the prediction of protein structure and is close to solve this grand challenge hanging over the scientific world for many years. In this talk\, I will describe how this technology emerged in the field\, how it overcame various technical hurdles to reach a high accuracy of predicting protein structures as demonstrated by AlphaFold2\, and where it is going now. I will present our latest work of applying 3D-equivariant graph neural networks with self- attention to evaluate and refine protein structural models. Our experiments demonstrate that 3D-equivariant graph network networks that are robust against the rotation and translation of 3D objects can evaluate and improve the quality of protein structures more effectively than the existing methods.
URL:https://www.scilifelab.se/event/3d-equivariant-graph-neural-networks-for-refining-and-evaluating-protein-structures/
LOCATION:Online event via Zoom
CATEGORIES:Event
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END:VCALENDAR