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DTSTART;TZID=Europe/Stockholm:20240416T083000
DTEND;TZID=Europe/Stockholm:20240418T150000
DTSTAMP:20260407T145459
CREATED:20231130T105230Z
LAST-MODIFIED:20240409T082417Z
UID:10001053-1713256200-1713452400@www.scilifelab.se
SUMMARY:IEC meeting
DESCRIPTION:SciLifeLab Infrastructure welcomes the International Evaluation Committee (IEC) to Uppsala\, Sweden\, on April 16-18 for a panel meeting during the Evaluation of the SciLifeLab Infrastructure. This international evaluation\, part of a series conducted every four years\, plays a crucial role in guiding SciLifeLab’s strategic development. \n\n\n\nThe international evaluation of the SciLifeLab infrastructure 2024 consists in short of  \n\n\n\ni. individual pre-evaluation done by each IEC member  \n\n\n\nii. the IEC meeting in Uppsala  \n\n\n\niii. the IEC report\, a joint evaluation report from IEC with consensus grades and assessments. In addition\, we would like input and recommendations in the IEC report on the centrally coordinated SciLifeLab functions Precision Medicine\, Planetary Biology and Pandemic Laboratory Preparedness\, Training Hub and Data Centre.  \n\n\n\n The IEC meeting in Uppsala provides an opportunity for in-depth discussions and evaluation of each platform and unit.  \n\n\n\nProgram\n\n\n\nProgram-IEC-2024Download\n\n\n\n\n\nMembers of the International Evaluation Committee\n\n\n\nIEC-membersDownload\n\n\n\n\n\n\n\nBiosketch IEC members\n\n\n\nBIOSKETCH-IECDownload
URL:https://www.scilifelab.se/event/iec-site-visit/
LOCATION:Navet\, SciLifeLab Uppsala\, SciLifeLab Uppsala\, BMC C11\, Husargatan 3\, Uppsala\, 75237\, Sweden
CATEGORIES:Event
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END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20240416T121500
DTEND;TZID=Europe/Stockholm:20240416T130000
DTSTAMP:20260407T145459
CREATED:20240409T072912Z
LAST-MODIFIED:20240409T072914Z
UID:10001226-1713269700-1713272400@www.scilifelab.se
SUMMARY:InfraVis\, a National Research Infrastructure For Data Visualization
DESCRIPTION:In the frame of the “SciLifeLab Site Umeå / KBC Infrastructure Seminar Series”\, the seminars will be organised every second Tuesday during spring 2024. The seminars will be held in a hybrid format – IRL in Glasburen\, KBC\, Umeå\, and online via Zoom. Learn more about the seminar series and Schedule for Spring 2024 here. \n\n\n\nOn 16 April\, at 12:15\, SciLifeLab Site Umeå / KBC Infrastructure Seminar Series presents: \n\n\n\nInfraVis\, a National Research Infrastructure For Data Visualization\n\n\n\nSpeakers: \n\n\n\nKarin Danielsson\, Associate Professor at the Department of Informatics\, Director of Humlab at the Faculty of Arts and Humanities\, and a member of InfraVis Steering Committee \n\n\n\nEvelina Liliequist\, Associate Professor at Humlab\, researcher at Centre for Regional Science at Umeå University\, and the node coordinator for UmU/Humlab in InfraVis \n\n\n\nDescription: The seminar will be a presentation of InfraVis\, a National Research Infrastructure For Data Visualization funded by VR. InfraVis aims to significantly improve data analysis support\, address new challenges involving large and complex data and create competitive advantages for researchers associated with Swedish universities or research institutes. \n\n\n\nInfraVis assists individual researchers\, research teams and research projects to visualize their research data from any scientific domain. Our definition of the term “visualization” includes all stages of data analysis in the visualization pipeline. Statistics\, machine learning\, and other tools are a part of the InfraVis arsenal. The data-driven analysis produces results that\, through methodical design\, have visual representations. These visual representations\, when interactive\, are visualizations that exploit the extraordinary ability of the human brain to detect\, classify\, and relate patterns and anomalies visually. InfraVis experts give access to state-of-the-art visualization competence\, support\, equipment\, training\, and methods. \n\n\n\nWe aim for more researchers at UmU to take advantage of the support InfraVis can bring. During the seminar we will explain further the possibilities with the infrastructure\, visualization expertise available\, and present some examples of InfraVis visualizations. \n\n\n\nLink to website: https://infravis.se \n\n\n\nRegistration: Sign up for the IRL seminar and reserve your free lunch (sandwich\, drink\, and little sweet snack) by Monday\, 15 April\, 10:00 a.m.: \n\n\n\n\nhttps://www.umu.se/en/chemical-biological-centre/kbc_events/registration-form-infrastructure-seminar2\n\n\n\n\nor follow online (registration is not required): \n\n\n\nMeeting URL: https://umu.zoom.us/j/67909354528Meeting ID: 679 0935 4528 \n\n\n\nOrganisers: SciLifeLab Site Umeå and Chemical Biological Centre (KBC)\, Umeå
URL:https://www.scilifelab.se/event/infravis-a-national-research-infrastructure-for-data-visualization/
LOCATION:Glasburen Seminar Room\, Chemical Biological Centre (KBC) Building\, Umeå University\, Umeå\, 901 87\, Sweden
CATEGORIES:Event
ORGANIZER;CN="SciLifeLab Ume%C3%A5":MAILTO:umea@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20240416T140000
DTEND;TZID=Europe/Stockholm:20240416T143000
DTSTAMP:20260407T145459
CREATED:20240405T094913Z
LAST-MODIFIED:20240405T094916Z
UID:10001225-1713276000-1713277800@www.scilifelab.se
SUMMARY:CSI Seminar: Practical Tools for Mental Fitness
DESCRIPTION:We are excited to host a new Coaching in Science Initiative (CSI) Seminar titled: ‘Practical Tools for Mental Fitness’ \n\n\n\nIn today’s fast-paced world\, maintaining mental well-being is essential. Join us as we delve into practical strategies and techniques to strengthen your mental resilience\, lower stress and process emotions. We will equip you with actionable tools to navigate life’s challenges\, including exercises in: mindfulness\, cognitive reframing and simple physical practices that can be done anywhere. \n\n\n\nDate: 16/04/2024 \n\n\n\nTime: 14:00 – 14:30 \n\n\n\nZoom link: https://kth-se.zoom.us/j/66943463637 \n\n\n\nOn-site location: Gamma 2 lunch room \n\n\n\nWe will begin with a ~ 20 min talk\, held in Solna and over zoom. Then proceed with a reflection and discussion held only on-site. We encourage other sites to form watch parties\, by listening in together to the talk and then hold their own discussion afterwards. Hopefully seeding many local chapters of CSI. \n\n\n\nTo help facilitate discussion and reflection\, consider the following starter questions: \n\n\n\nAwareness: where do we experience mental fitness in our lives? \n\n\n\nAnalysis: how well do I currently engage in mental fitness practices? \n\n\n\nAlternative: how could we relate to mental fitness\, in ourselves and others? \n\n\n\nAction: how will knowledge of mental fitness change my decisions going forward? \n\n\n\nPlease forward this to friends and colleagues! \n\n\n\nYours sincerely\, \n\n\n\nThe CSI Team \n\n\n\nhttps://www.thecoachinginscienceinitiative.org/\n\n\n\nhttps://www.youtube.com/@TheCoachinginScienceInitiative
URL:https://www.scilifelab.se/event/csi-seminar-practical-tools-for-mental-fitness/
LOCATION:Gamma 2 Lunchroom\, SciLifeLab\, Tomtebodavägen 23\, Solna\, Sweden
CATEGORIES:Event
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ORGANIZER;CN="Coaching in Science Initiative (CSI)":MAILTO:sami.saarenpaa@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20240416T150000
DTEND;TZID=Europe/Stockholm:20240416T160000
DTSTAMP:20260407T145459
CREATED:20240305T103431Z
LAST-MODIFIED:20240326T124907Z
UID:10001188-1713279600-1713283200@www.scilifelab.se
SUMMARY:Sequenceable DNA tools for Medicine: Transcriptomics and Antibody alternatives
DESCRIPTION:Spotlight Seminar series presents Erik Benson\, SciLifeLab Fellow at Karolinska Institutet \n\n\n\nErik Benson is a SciLifeLab Fellow at the department of Microbiology\, Tumor and Cell Biology at KI since January 2024. He is working on combining DNA structures with sequencing and selection. He previously held postdoc positions at the department of Physics\, University of Oxford and the department of Gene Technology at KTH. He did his PhD at Karolinska Institute and MSc in medical physics in Lund. \n\n\n\nHost: Jean Hausser\, KI
URL:https://www.scilifelab.se/event/sequenceable-dna-tools-for-medicine-transcriptomics-and-antibody-alternatives/
LOCATION:Air&Fire\, SciLifeLab Stockholm\, Tomtebodavägen 23A\, Solna\, Sweden
CATEGORIES:Event
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ORGANIZER;CN="Spotlight Seminar Series":MAILTO:events@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20240417T100000
DTEND;TZID=Europe/Stockholm:20240417T110000
DTSTAMP:20260407T145459
CREATED:20240326T154451Z
LAST-MODIFIED:20251204T144742Z
UID:10001218-1713348000-1713351600@www.scilifelab.se
SUMMARY:Research involving human data - what do I need to think of as a researcher?
DESCRIPTION:This seminar will focus on collecting and using personal data in research. We will guide you through the different phases of a typical research project and discuss some commonly asked questions. We will\, for example\, talk about practical aspects of the ethical review\, GDPR\, and how to share sensitive data. This is the third event in the SciLifeLab Data Management seminar series Spring 2024. \n\n\n\nWhen: Wednesday April 17\, 10-11 CEST (Zoom) \n\n\n\nSpeakers: Markus Englund and Erik Hedman\, Data Stewards\, NBIS. \n\n\n\nRegister\n\n\n\nSciLifeLab Data Management seminar series is an event series by the SciLifeLab Data Centre and NBIS joint Data Management team aimed at both the life science research community and infrastructure\, and others with an interest in research data management in life sciences. The events will showcase how to put the FAIR principles\, and good data management into practice. The goal of the events in this seminar series is to provide interesting seminars around topics related to research data management in general but also to foster discussions around best practices and how they can be improved. The events takes place virtually (over Zoom) and are open to everyone (researchers\, staff\, RDM professionals etc.) working at or affiliated with a Swedish research institute or university. Each event is scheduled for 60 minutes\, including 15 minutes for discussions and Q & A. The videos will be published openly after the seminars at the SciLifeLab YouTube channel.More information about SciLifeLab Data Centre and NBIS joint Data Management team: https://data-guidelines.scilifelab.se/ \n\n\n\nWelcome! \n\n\n\nOrganisers: SciLifeLab Data Centre and NBIS National Bioinformatics Infrastructure SwedenFor more information or inquiries please contact: data-management@scilifelab.se
URL:https://www.scilifelab.se/event/research-involving-human-data-what_to-think_of/
CATEGORIES:Event
ORGANIZER;CN="Open Science Seminar Series":MAILTO:data-management@scilifelab.se
LOCATION:
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20240418T100000
DTEND;TZID=Europe/Stockholm:20240418T110000
DTSTAMP:20260407T145459
CREATED:20240328T075011Z
LAST-MODIFIED:20240404T101946Z
UID:10001214-1713434400-1713438000@www.scilifelab.se
SUMMARY:Leveraging supercomputers for data-driven life science research: examples from Berzelius
DESCRIPTION:This event is part of the Tools for AI/ML research in life sciences event series arranged by the SciLifeLab Data Centre. This webinar is organized in collaboration with the National Supercomputer Centre\, LiU as well as the EuroHPC National Competence Centre Sweden (ENCCS). \n\n\n\nTitle: Leveraging supercomputers for data-driven life science research: examples of use cases and introduction to Berzelius \n\n\n\nSpeaker: Soumi Chaki and Xuan Gu (National Supercomputer Centre\, Linköping University)\, Kimmo Kartasalo (Karolinska Institute)\, Claudio Mirabello (Linköping University). \n\n\n\nWhere and when: April 18\, 2024 at 10:00-11:00 Stockholm time\, online. Registration is open till April 18 at 9:00.  \n\n\n\nAbstract:  \n\n\n\nAgenda:10:00-10:05 – Introduction to supercomputers and Berzelius10:05-10:20 – Developing computational pathology AI models for improved prostate cancer diagnostics and prognostics using Berzelius (Kimmo Kartasalo\, Post-doctoral researcher\, Karolinska Institute)10:20-10:35 – Modelling large protein complexes on Berzelius (Claudio Mirabello\, Principal Research Engineer\, Docent\, Linköping University)10:35-10:50 – Resource allocation procedure and user support available on Berzelius10:50-11:00 – Q&A session \n\n\n\nPowerful GPU supercomputers allow to carry out large-scale experiments in a fraction of time that it would otherwise take as well as pursue research projects that would otherwise not be possible. Life science researchers at Swedish universities can apply and make use of the Berzelius AI/ML cluster at the National Supercomputer Center in Linköping. In this one hour long webinar two researchers will present how they use Berzelius in their work and what research it allows them to carry out. In addition\, we will present the technical specifications of Berzelius\, the resource allocation procedure\, as well as the available user support. We will give a short demonstration on how to request GPU resources on Berzelius and run scripts/software on the allocated GPU(s). This webinar is particularly tailored for researchers interested in and working with AI/ML methods. \n\n\n\nRegister to join the event\n\n\n\nMore about the event series: \n\n\n\nTools for AI/ML research in life sciences is an event series by the SciLifeLab Data Centre aimed at life science researchers who use machine learning methods in their work. The goal of the events in this series is to provide introductions to different tools for ML research but also to foster discussions around our practices and how they can be improved. The events takes place virtually (over Zoom) and are open to researchers in Sweden and beyond. Each event is scheduled for 60 minutes\, consisting of a talk and an extended discussion. Follow the page of the event series to learn about future seminars. \n\n\n\nFor questions about the events please contact the organizing team by emailing  serve@scilifelab.se  \n\n\n\n \n\n\n\nScientific lead: Prof. Ola Spjuth\, SciLifeLab Data Centre and Uppsala University and DDLS \n\n\n\nContact information: serve@scilifelab.se
URL:https://www.scilifelab.se/event/leveraging-supercomputers/
LOCATION:Online event via Zoom
CATEGORIES:Event
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20240419T100000
DTEND;TZID=Europe/Stockholm:20240419T110000
DTSTAMP:20260407T145459
CREATED:20240115T121853Z
LAST-MODIFIED:20240115T121929Z
UID:10001109-1713520800-1713524400@www.scilifelab.se
SUMMARY:Model-guided ML approaches to integrative omics analyses
DESCRIPTION:NBIS\, Scilifelab’s Bioinformatics platform\, arranges an open AI and IO Seminar Series aimed at knowledge-sharing about Artificial Intelligence and Integrative Omics (AI & IO) analysis and applications in the Life Science community. The seminar series is open to everyone. The seminar is run over Zoom on the third Friday of the month during academic terms\, typically between 10 and 11 am\, with ca. 45 min long presentation and 15 min discussion. \n\n\n\nFor further info\, please see this website. \n\n\n\n \n\n\n\n\n\n\n\nModel-guided ML approaches to integrative omics analyses\n\n\n\nCemal Erdem\, DDLS fellow\, Umeå University \n\n\n\nClick here to join zoom conference
URL:https://www.scilifelab.se/event/model-guided-ml-approaches-to-integrative-omics-analyses/
LOCATION:Online event via Zoom
CATEGORIES:Event
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20240423T120000
DTEND;TZID=Europe/Stockholm:20240423T130000
DTSTAMP:20260407T145459
CREATED:20240418T072500Z
LAST-MODIFIED:20240418T072503Z
UID:10001232-1713873600-1713877200@www.scilifelab.se
SUMMARY:Building capacity to upskill the community: How the SciLifeLab Training Hub can help
DESCRIPTION:In the frame of the “SciLifeLab Site Umeå / KBC Infrastructure Seminar Series”\, the seminars will be organised every second Tuesday during spring 2024. The seminars will be held in a hybrid format – IRL in Glasburen\, KBC\, Umeå\, and online via Zoom. Learn more about the seminar series and Schedule for Spring 2024 here. \n\n\n\n \n\n\n\nOn 23 April\, at 12:00\, SciLifeLab Site Umeå / KBC Infrastructure Seminar Series presents: \n\n\n\nBuilding capacity to upskill the community: How the SciLifeLab Training Hub can help\n\n\n\nPresenter: \n\n\n\nNina Norgren\, Training Manager\, Umeå University. \n\n\n\nDescription: Come join us for a session that is all about boosting skills and training the community with the Scilifelab Training Hub. We will be presenting how the Training Hub can support your platform/unit in designing and delivering training to your users. Whether you are just starting out or looking to level up your skills\, we have resources and support to help you along the way. Everyone interested in training is welcome! \n\n\n\nMore about SciLifeLab Training Hub: https://www.scilifelab.se/training/ \n\n\n\nVisit the new Training Portal to see all our courses and materials: https://training.scilifelab.se/ \n\n\n\nRegistration: Sign up for the IRL seminar and reserve your free lunch (sandwich\, drink\, and little sweet snack) by Monday\, 22 April\, 10:00 a.m.: \n\n\n\n\nhttps://www.umu.se/en/chemical-biological-centre/kbc_events/registration-form-infrastructure-seminar\n\n\n\n\nor follow online (registration is not required): \n\n\n\nMeeting URL: https://umu.zoom.us/j/67909354528Meeting ID: 679 0935 4528 \n\n\n\nOrganisers: SciLifeLab Site Umeå and Chemical Biological Centre (KBC)\, Umeå \n\n\n\nOrganizer:KBC \n\n\n\nEvent type:Seminar
URL:https://www.scilifelab.se/event/building-capacity-to-upskill-the-community-how-the-scilifelab-training-hub-can-help/
LOCATION:Glasburen Seminar Room\, Chemical Biological Centre (KBC) Building\, Umeå University\, Umeå\, 901 87\, Sweden
CATEGORIES:Event
ATTACH;FMTTYPE=image/jpeg:https://www.scilifelab.se/wp-content/uploads/2024/04/SciLifeLab-Site-Umea-seminar-scaled.jpg
ORGANIZER;CN="SciLifeLab Ume%C3%A5":MAILTO:umea@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20240425T113000
DTEND;TZID=Europe/Stockholm:20240426T170000
DTSTAMP:20260407T145459
CREATED:20231221T105648Z
LAST-MODIFIED:20240425T193524Z
UID:10001075-1714044600-1714150800@www.scilifelab.se
SUMMARY:Cell and Molecular Biology - DDLS symposium
DESCRIPTION:Welcome to the Cell and Molecular Biology Symposium\, starting with lunch at Restaurant Lyktan from 11:30. The conference then takes place in the Birgit Thilander Lecture Hall in Academicum. The program includes presentations from local and national experts within data driven life science research – and a keynote lecture by Prof. Edda Klipp from the Humboldt University in Berlin. \n\n\n\nDay two\, on April 26\, takes place in the AstraZeneca facilities in Mölndal. Here we will meet with the exciting BioVenture Hub and learn about how AstraZeneca works with data driven life science in a clinical setting. Bus transfer from Clarion Hotel Post leaves at 07:30 directly to Astra Zeneca. \n\n\n\n\nPractical information\n\n\n\n\n\nPublic Transport to Medicinareberget \n\n\n\nThursday\, April 27 \n\n\n\nPlease note that due to construction work\, there are disturbances in the tram operations at nearby stops Medicinaregatan and Sahlgrenska Huvudentrén. \n\n\n\nFind your best route through the Västtrafik website or app. \n\n\n\n\n\nCoach to Astra Zeneca \n\n\n\nFriday\, April 26 \n\n\n\nA chartered bus will depart from Clarion Post Hotel at 07:30\, directly to the Astra Zeneca Conference Center (PGN Entrance).  \n\n\n\n\n\nGuidelines for Self-Transport Arrivals to Astra Zeneca \n\n\n\nFriday\, April 26 \n\n\n\nWhether you’re arriving by public transport\, bike\, or car\, kindly make your way to the KC-entrance at Pepparedsleden 1. \n\n\n\nPlease be punctual at 08:00\, as you’ll be guided from the entrance to the conference area. \n\n\n\n\n\n\nProgram\n\n\n\nClick to expand and see the program \n\n\n\nThursday\, April 25\nApril 2510:30Expert Group meeting11:30LunchRestaurant Lyktan13:00Welcome WordsMargit Mahlapuu\, University of GothenburgSverker Holmgren\, ChalmersOla Engkvist\, AstraZeneca13:10Precision Glycomics: How AI and advanced mass spectrometry are changing the gameDaniel Bojar\, University of Gothenburg13:40Towards a universal molecular framework for structure prediction and designPatrick Bryant\, SciLifeLab/Stockholm University (DDLS Fellow)Protein-ligand docking is an established tool in drug discovery and development to narrow down potential therapeutics for experimental testing. However\, a high-quality protein structure is required and often the protein is treated as fully or partially rigid. Here we develop an AI system that can predict the fully flexible all-atom structure of protein-ligand complexes directly\, given a multiple sequence alignment representation of the protein\, protein pocket information\, and a SMILES string representing the ligand.14:10Integrating single-cell transcriptomics with cellular phenotypesJoan Camuñas\, University of Gothenburg14:40Thermodynamics-informed modeling of biochemical reaction and regulation networksEdda Klipp\, Humboldt-Universität zu Berlin15:20Coffee Break15:50Tumor biology using multiomicsAnders Ståhlberg\, University of Gothenburg16:10Multiomics – state of art data generation and analysis at NGIMattias Ormestad and Franziska Bonath\, National Genomics InfrastructureMultiomics projects can span over long time frames\, sometimes years\, until all data is created. Often sequencing is an integral part and is outsourced to a core facility like NGI. For projects in which data generation is performed by different groups\, it is crucial that important information about library preparation\, sequencing and analysis is recorded and available to all other participants. Therefore\, NGI applies quality control measures and reports important metadata to ensure that our users can use our data with confidence even years after data generation.16:30Data-Driven Microscopy: the automation of end-to-end imaging workflowsElisabet Carlsohn and Rafael Camacho\, SciLifeLab/University of GothenburgBiological complexity mandates comprehensive imaging for statistically significant results. Manual operation impedes large dataset acquisition\, affecting reproducibility. Smart microscopy\, integrating image analysis and computer-controlled microscopes\, streamlines workflows. At GU’s Centre for Cellular Imaging\, we offer open-access “smart microscopy” services optimizing data management with next-gen file formats\, ome-zarr\, community-driven visualization tools\, napari\, and collaborative platforms\, webknossos. This ensures efficient resource utilization in the era of data-driven life sciences.17:00Tour to SciLifeLab units in Gothenburg Optional\, sign up in registration form18:00Dinner for CMB fellows and experts\, and speakers\n\n\n\n \n\n\n\n\nFriday\, April 26\nApril 2607:30Bus transport to Astra Zeneca Conference Centre in Mölndal08:00Visitor registration Astra Zeneca Conference Centre in Mölndal08:25IntroductionOla Engkvist\, AstraZeneca & Margit Mahlapuu\, University of Gothenburg08:30Empowering data-driven innovations in Life Sciences: A journey with GU VenturesKlementina Österberg\, GU Ventures & Carl-Peter Mattsson\, GU VenturesKlementina Österberg CEO & Carl-Peter Mattsson Investment director at GU Ventures will present their experiences and the journeys to create successful new business in collaborations with investors\, industry and the eco system. They will also show some examples of these journeys with their companies.09:15BioVentureHub – an antidote to the incubent’s curseMagnus Björsne\, AstraZeneca BioVentureHub10:00Coffee Break10:30Precision Medicine from the start – using omic data to deliver actionable insight to drug discovery and developmentDaniel Muthas\, AstraZeneca11:15Data driven life sciences in a clinical settingJesper Havsol\, AstraZeneca12:00Networking lunch12:40Tour –  “The Amazing Journey the story about Astra Zeneca in Mölndal”Optional\, sign up in registration form\n\n\n\n \n\n\n\n\nSymposium Program for Download and PrintDownload\n\n\n\nData-driven Life Science\n\n\n\nThe future of life science is data-driven\, providing major new opportunities to explore and understand biology\, human health and changing ecosystems. The SciLifeLab & Wallenberg National Program for Data-Driven Life Science (DDLS) is set up to make use of these opportunities.
URL:https://www.scilifelab.se/event/ddls-symposium-cell-and-molecular-biology/
LOCATION:Birgit Thilander Lecture Hall\, Medicinaregatan 3\, Göteborg
CATEGORIES:Event
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20240502T090000
DTEND;TZID=Europe/Stockholm:20240502T093000
DTSTAMP:20260407T145459
CREATED:20240130T122610Z
LAST-MODIFIED:20240502T063112Z
UID:10001131-1714640400-1714642200@www.scilifelab.se
SUMMARY:Cancelled: The role of diagnostics in precision cancer medicine
DESCRIPTION:This event has been cancelled. We apologize for the inconvenience. \n\n\n\n \n\n\n\n \n\n\n\nClinical Talks \n\n\n\nClinical Talks is an educational seminar series open to everyone. It is organized by the SciLifeLab Precision Medicine Capability\, and invites a mixture of speakers that are experts with a clinical perspective on topics concerning rare diseases\, cancer\, microbiology and bioinformatics. \n\n\n\nHealth is individual and patients can benefit greatly from personalized treatments\, tailored for their specific molecular disposition. This rapidly emerging field\, known as Precision Medicine\, relies on technology development and requires close collaboration between scientists and healthcare professionals. SciLifeLab aims to bring cutting-edge technologies\, first-class expertise and data infrastructure to build the foundation of tomorrow’s Precision Medicine.
URL:https://www.scilifelab.se/event/the-role-of-diagnostics-in-precision-cancer-medicine/
LOCATION:Online event via Zoom
CATEGORIES:Event
ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2024/01/Clinical-Talks-sq.png
ORGANIZER;CN="Clinical Talks":MAILTO:precisionmedicine@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20240502T090000
DTEND;TZID=Europe/Stockholm:20240503T170000
DTSTAMP:20260407T145459
CREATED:20240313T114938Z
LAST-MODIFIED:20240404T123511Z
UID:10001205-1714640400-1714755600@www.scilifelab.se
SUMMARY:Protistology Nordics Meeting 2024
DESCRIPTION:The Protistology Nordics 2024 will be held in Uppsala\, providing an opportunity for scientists in Nordic countries to come together and showcase their research on the genetics\, cell biology\, ecology\, and evolution of protists.The meeting is designed to facilitate vibrant discussions about the latest research in protistology\, social interaction\, and networking with fellow participants. \n\n\n\nThis meeting is sponsored by the Planetary Biology Capability. Apart from assisting the organizers\, the Capability is coordinating an interactive session to discuss opportunities and challenges to use SciLifeLab platforms. \n\n\n\n\n\n\n\nBrief Program\n\n\n\n2 May 2024Workshop for Early Career Researchers\, and Pub NightA workshop for Masters students\, PhD students\, and postdocs!3 May 2024Symposium on Protist Cell Biology\, Ecology\, and Evolution \n\n\n\nImportant dates\n\n\n\nRegistration and Abstract Submission Deadline: 25 March 2024Selected abstracts/Participants Will Be Notified By: 2 April 2024 \n\n\n\n\n\n\n\nRegister here!\n\n\n\nConference website
URL:https://www.scilifelab.se/event/protistology-nordics-meeting-2024/
LOCATION:Evolutionsbiologiskt centrum (EBC)\, Norbyvägen 18\, Uppsala\, Sweden
CATEGORIES:Event
ORGANIZER;CN="SciLifeLab Planetary Biology Strategic Area":MAILTO:anabella.aguilera@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20240502T161500
DTEND;TZID=Europe/Stockholm:20240502T170000
DTSTAMP:20260407T145459
CREATED:20240430T103634Z
LAST-MODIFIED:20240430T103635Z
UID:10001248-1714666500-1714669200@www.scilifelab.se
SUMMARY:Biology is predictable!
DESCRIPTION:Seminar by Professor Lucas Pelkmans from the University of Zurich. \n\n\n\nRead more
URL:https://www.scilifelab.se/event/biology-is-predictable/
LOCATION:Air&Fire\, SciLifeLab Stockholm\, Tomtebodavägen 23A\, Solna\, Sweden
CATEGORIES:Event
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20240506T151500
DTEND;TZID=Europe/Stockholm:20240506T161500
DTSTAMP:20260407T145459
CREATED:20240409T150217Z
LAST-MODIFIED:20240411T124823Z
UID:10001227-1715008500-1715012100@www.scilifelab.se
SUMMARY:[The Svedberg seminar] Genetics of Type 2 Diabetes: Advances\, Prospects\, and Challenges
DESCRIPTION:Benjamin F. Voight \n\n\n\nAssociate Professor\, Pharmacology and GeneticsUniversity of Pennsylvania – Perelman School of Medicine\, USA \n\n\n\n \n\n\n\n\n\n\n\nBio\n\n\n\nBen Voight received his PhD from the University of Chicago\, with postdoctoral training at Massachusetts General Hospital\, staying on at the Broad Institute as a research scientist. He is currently an Associate Professor at the University of Pennsylvania in the Department of Systems Pharmacology and Translational Therapeutics\, and the Department of Genetics. As a human geneticist\, research from his group focuses on understanding the genetic\, biological\, and evolutionary basis of metabolic phenotypes in human populations\, particularly diabetes\, cardiovascular\, and liver disease. Recent data scientific efforts focus on new association studies for discovery using biobank-scale data (e.g.\, the Million Veteran Program)\, post-association study analyses to understand the genetic architecture of disease and ultimately the underlying causal variants\, and quantitative trait locus mapping for expression and chromatic accessibility using primary pancreas and liver data sets. \n\n\n\n \n\n\n\nGenetics of Type 2 Diabetes: Advances\, Prospects\, and Challenges\n\n\n\n \n\n\n\nType 2 diabetes is a heterogeneous disease that develops through diverse pathophysiological processes and molecular mechanisms. Elucidating the processes and mechanisms by identifying new loci associated with disease\, the underlying causal variants and genes\, and the cell types of action are areas of current focus by the research community. I will describe recent contributions by the Type 2 Diabetes Global Genomic Initiative\, our newly minted consortium focused on expanding locus discovery across diverse ancestries\, understanding physiological mechanism and prediction of susceptibility to complications through genetic subtyping\, and nomination of putative causal genes and mechanism through statistical colocalization. I will also briefly discuss prospects for exciting potential advances in the near term from new data types and improved computational methods\, as well as my perceptions of open challenges and potential thoughts on how to take those on – ultimately to understand disease etiology and to generate prospects for therapeutic intervention. \n\n\n\n \n\n\n\n\n\n\n\nHost: Marcel den Hoed marcel.den_hoed@igp.uu.se UU
URL:https://www.scilifelab.se/event/the-svedberg-seminar-benjamin-voight/
LOCATION:BMC Room C8:301\, Husargatan 3\, Uppsala\, Sweden
CATEGORIES:Event
ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2022/02/Picture1-The-Svedberg.png
ORGANIZER;CN="The Svedberg Seminar Series":MAILTO:thesvedberg@scilifelab.uu.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20240507T120000
DTEND;TZID=Europe/Stockholm:20240507T130000
DTSTAMP:20260407T145459
CREATED:20240424T062341Z
LAST-MODIFIED:20240424T062500Z
UID:10001239-1715083200-1715086800@www.scilifelab.se
SUMMARY:Advanced Technologies for Spatial Omics
DESCRIPTION:SciLifeLab Site Umeå / KBC Infrastructure Seminar Series presents: \n\n\n\nAdvanced Technologies for Spatial Omics\n\n\n\nPresenter: \n\n\n\nKatarina Tiklova\, PhD\, Head of the in situ sequencing unit\, Science for Life Laboratory \n\n\n\nDescription: The seminar will present In situ sequencing technology\, which is part of SciLifeLab’s spatial platform. \n\n\n\nThe advancements of single cell spatial imaging analysis provided by In Situ Sequencing gives scientists the capability to view their samples with subcellular resolution\, by profiling up to 1\,000s of targets\, each in the context of their spatial localization patterns. This type of analysis enables studies to not only locate and type cells within their biological context\, but also address questions about cell–cell communication\, profile cellular microenvironments\, and identify rare cell infiltration. \n\n\n\nMore about In Situ Sequencing Infrastructure Unit: https://www.scilifelab.se/units/in-situ-sequencing/ \n\n\n\nRegistration: Sign up for the IRL seminar and reserve your free lunch (sandwich\, drink\, and little sweet snack) by Monday\, 6 May\, 10:00 a.m.:https://www.umu.se/en/chemical-biological-centre/kbc_events/registration-form-infrastructure-seminar2/ \n\n\n\nor follow online (registration is not required):Meeting URL: https://umu.zoom.us/j/67909354528Meeting ID: 679 0935 4528 \n\n\n\nOrganisers: SciLifeLab Site Umeå and Chemical Biological Centre (KBC)\, Umeå \n\n\n\n\n\n\n\nIn the frame of the “SciLifeLab Site Umeå / KBC Infrastructure Seminar Series”\, the seminars will be organised every second Tuesday during spring 2024. The seminars will be held in a hybrid format – IRL in Glasburen\, KBC\, Umeå\, and online via Zoom. Learn more about the seminar series and Schedule for Spring 2024 here.
URL:https://www.scilifelab.se/event/advanced-technologies-for-spatial-omics/
LOCATION:Glasburen Seminar Room\, Chemical Biological Centre (KBC) Building\, Umeå University\, Umeå\, 901 87\, Sweden
CATEGORIES:Event
ATTACH;FMTTYPE=image/jpeg:https://www.scilifelab.se/wp-content/uploads/2024/04/SciLifeLab-Site-Umea-seminar-1-scaled.jpg
ORGANIZER;CN="SciLifeLab Ume%C3%A5":MAILTO:umea@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20240508T090000
DTEND;TZID=Europe/Stockholm:20240508T163000
DTSTAMP:20260407T145459
CREATED:20231221T084645Z
LAST-MODIFIED:20240502T094429Z
UID:10001074-1715158800-1715185800@www.scilifelab.se
SUMMARY:Aiming for the clinics
DESCRIPTION:– Strengthened interactions in translational medicine\n\n\n\n\n\nWelcome to this symposium in translational medicine jointly organized by the Drug Discovery and Development Platform at SciLifeLab and Uppsala Clinical Research Center. \n\n\n\n \n\n\n\n\nDate: May 8\, 2024Time: 09:00-16:30Venue: Lecture hall IX\, University Main Building\, Uppsala (Universitetshuset) \n\n\n\n\nThere is a large gap between basic scientific research and translation to novel therapeutics\, and to bridge this gap\, translational research and knowledge need to be strengthened. In this seminar\, we aim to bring preclinical and clinical expertise together by highlighting and discussing some of the hurdles to overcome in order to progress from preclinical to clinical studies and make novel drugs available to the patients. We will show some of the resources available within SciLifeLab and the broader community\, and there will be ample time for inspirational case studies that have succeeded in bringing academic as well as small biotech discoveries into clinical phase. These cases include different modalities and the differences in ways to move forward depending on drug modality will be shown. Concrete expert and scientific advice will be given in different areas of preclinical and clinical trials including biostatistics and national regulatory guidelines. There will also be time for networking and interaction between academic researchers\, scientists from the SciLifeLab infrastructure as well as the broader community. \n\n\n\n \n\n\n\nMeet the experts from: \n\n\n\nRISE (Research Institutes of Sweden)\, Testa Center\, SciLifeLab Drug Discovery & Development\, Uppsala University Innovation\, The Swedish Drug Delivery Center (SweDeliver)\, CCRM Nordic\, Uppsala Clinical Research Center (UCR)\, ATMP-Center Uppsala\, UU samverkan and Uppsala Preclinical Cancer Treatment Center\, Precisionsmedicinskt centrum Uppsala (PMCU)\, NorthX Biologics and The Swedish Medical Products Agency (Läkemedelsverket). \n\n\n\nRegister for the Conference\n\n\n\nRegistration closed May 1. If you want to register\, please contact erika.erkstam@scilifelab.uu.se. We may have seats available in case of late cancellations.  \n\n\n\nFor late cancellations\, please follow the cancellation link in your personal confirmation letter so we can let someone else take your place. \n\n\n\nRead more about the DDD Platform\n\n\n\nProgram\n\n\n\nupdated 2024-04-29 \n\n\n\nConference_UCR_SciLifeLab-DDD_agenda_240429Download\n\n\n\nFlyer\n\n\n\nAiming-for-the-clinics_2024_extended-final-1Download
URL:https://www.scilifelab.se/event/aiming-for-the-clinics/
LOCATION:University Main Building\, Biskopsgatan 3\, Uppsala\, 75310
CATEGORIES:Event
ATTACH;FMTTYPE=image/jpeg:https://www.scilifelab.se/wp-content/uploads/2023/12/Universitetshuset-vinter.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20240513T080000
DTEND;TZID=Europe/Stockholm:20240514T170000
DTSTAMP:20260407T145459
CREATED:20240418T072721Z
LAST-MODIFIED:20240422T114352Z
UID:10001233-1715587200-1715706000@www.scilifelab.se
SUMMARY:SciLifeLab Research Data Management Roadshow 2024
DESCRIPTION:SciLifeLab Data Centre and NBIS\, in collaboration with SciLifeLab Umeå\, welcome you to join a 2-day event with presentations\, workshops\, & networking. \n\n\n\nSciLifeLab Data Management is a collaborative activity between SciLifeLab Data Centre and NBIS Data Management team. Together we support and collaborate with the Swedish life sciences research community and infrastructure. Our aims are to: maximize the value of life science data\, highlight and disseminate information about Open Science\, FAIR\, and good RDM practices\, offer services\, tools\, and support\, and offer courses and training. \n\n\n\nSciLifeLab Research Data Management Roadshow will visit all SciLifeLab sites during 2024 and 2025. \n\n\n\nDuring the Roadshow Umeå\, the following activities are offered: \n\n\n\n(1) Lunch seminar “Overview of Research Data Management services and support available locally and from SciLifeLab”\, 13 May 12:00-13:00\, Stora Fokusrummet (KB.G3.01)\, KBC \n\n\n\nThe seminar will be organised in the frame of the “SciLifeLab Site Umeå / KBC Infrastructure Seminar Series” \n\n\n\nTarget group: PhD students\, postdocs\, researchers and infrastructure staff \n\n\n\n(2) FAIR Frukost\, 14 May\, 9:00-10:00\, Glasburen\, KBC\n\n\n\nTarget group: PhD students and postdocs \n\n\n\n(3) Workshop\, 14 May\, Stora Fokus rummet (KB.F3.01)\n\n\n\nPart I: Data Management Plans\, 14 May\, 10:00-12:00 \n\n\n\nPart II: Data submission to public repositories\, 14 May\, 13:00-15:00 \n\n\n\nTarget group: PhD students\, postdocs\, researchers and infrastructure staff \n\n\n\nFind more information and register: https://www.umu.se/en/chemical-biological-centre/kbc_events/rdm-roadshow-2024/ \n\n\n\nRegistration deadline: 6 May
URL:https://www.scilifelab.se/event/scilifelab-research-data-management-roadshow-2024/
LOCATION:KBC Building Umeå\, Linneaus Väg 6\, Umeå
CATEGORIES:Event
ATTACH;FMTTYPE=image/jpeg:https://www.scilifelab.se/wp-content/uploads/2024/04/240513-240514_Umea-digital-sign-RDM-roadshow.jpg
ORGANIZER;CN="SciLifeLab Ume%C3%A5":MAILTO:umea@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20240513T090000
DTEND;TZID=Europe/Stockholm:20240514T160000
DTSTAMP:20260407T145459
CREATED:20240110T084457Z
LAST-MODIFIED:20240110T084615Z
UID:10001103-1715590800-1715702400@www.scilifelab.se
SUMMARY:Harnessing AI Transforms Research: Smart Strategies for Advanced Productivity
DESCRIPTION:SciLifeLab Gothenburg invites you to a hands-on workshop during two days led by PD Dr. Daniel Mertens\, who is a biochemist and group leader at the German Cancer Research Center (DKFZ) and at the University of Ulm. He is both a successfull scientist\, with more than 100 publications within life science that have been cited more than 5000 times (Daniel Mertens – Web of Science Core Collection) and an experienced lecturer\, who has been training scientists\, physicians\, administrators and other staff in different transferable skills (www.scientistsneedmore.de). So far\, more than 4000 participants have taken part in his international workshops around the world. Take the chance to learn more about how to use AI to increase your scientific productivity and quality in this instructive hands-on workshop lead by Dr. Mertens! \n\n\n\nThe workshop will cover these topics: \n\n\n\n\nWhy use AI? Productivity and quality increase.\n\n\n\nHow do LLMs work?\n\n\n\nPrompting like a Pro\n\n\n\nUsing AI for structuring text\, and telling a story\n\n\n\nUsing AI for brainstorming of experiments and projects\n\n\n\nUsing AI for decision making\, introspection\, career development and for training of interpersonal interactions\n\n\n\nGood Scientific Practice using AI Assistants: plagiarism\, copyright\, usage for brainstorming\, publishing and for grant writing\n\n\n\n\n\n\n\n\nmore information and registration
URL:https://www.scilifelab.se/event/harnessing-ai-transforms-research-smart-strategies-for-advanced-productivity/
LOCATION:Conference Centre Wallenberg\, Medicinaregatan 20A\, Gothenburg\, 413 90\, Sweden
CATEGORIES:Event
ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2024/01/AIworkshop8.png
ORGANIZER;CN="SciLifeLab Gothenburg":MAILTO:gothenburg@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20240513T110000
DTEND;TZID=Europe/Stockholm:20240513T120000
DTSTAMP:20260407T145459
CREATED:20240430T071038Z
LAST-MODIFIED:20240513T045222Z
UID:10001247-1715598000-1715601600@www.scilifelab.se
SUMMARY:New insights into the lateral organization of biological membranes: Investigating the role of membrane dipole potential and the midplane interface
DESCRIPTION:Seminar by Frederick A. Heberle\, Department of Chemistry\, University of Tennessee\, Knoxville\, TN\, USA \n\n\n\nAbstract\n\n\n\nCells can dynamically alter the spatial organization of lipids and proteins in the plasma membrane to regulate processes including cell signaling. The size and morphology of membrane domains\, and how these depend on lipid composition\, have drawn attention as potentially key variables in these processes. Model membrane studies have proven invaluable for elucidating the influence of phospholipid chains and headgroups\, as well as cholesterol concentration\, on membrane properties and phase behavior. Using this kind of bottom-up approach\, my group employs a diverse set of biophysical techniques including fluorescence microscopy and spectroscopy\, small-angle neutron scattering\, and cryogenic electron microscopy to characterize the phase behavior of lipid bilayer mixtures. In this talk\, I will show how two important yet poorly understood features of lipid membranes—namely\, the membrane dipole potential and the midplane interface of a compositionally asymmetric bilayer—can profoundly affect lateral lipid organization. \n\n\n\nZoom link
URL:https://www.scilifelab.se/event/new-insights-into-the-lateral-organization-of-biological-membranes-investigating-the-role-of-membrane-dipole-potential-and-the-midplane-interface/
LOCATION:Air&Fire\, SciLifeLab Stockholm\, Tomtebodavägen 23A\, Solna\, Sweden
CATEGORIES:Event
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20240515T150000
DTEND;TZID=Europe/Stockholm:20240515T154500
DTSTAMP:20260407T145459
CREATED:20240507T093945Z
LAST-MODIFIED:20240507T094614Z
UID:10001255-1715785200-1715787900@www.scilifelab.se
SUMMARY:Catalyzing Confidence: A Novel Strategy for Enhancing DEL Hit Validation in Drug Discovery
DESCRIPTION:Drug Discovery Seminars: Catalyzing Confidence: A Novel Strategy for Enhancing DEL Hit Validation in Drug Discovery \n\n\n\nPresenter: Dr Stefan Geschwindner\, PhD\, Director Biophysics\, AstraZeneca\, Mölndal\, Sweden \n\n\n\nHost: Pauliina Turunen\, Unit Target Protein Engineering (TPE)\, SciLifeLab DDD \n\n\n\n\n\n\n\nAbstract\n\n\n\nIn the realm of drug discovery\, validating hits derived from DNA-encoded library (DEL) screening is an indispensable step. This process necessitates the resynthesis and retesting of compounds to ascertain the consistency of observed activity while mitigating experimental artifacts. However\, the complexity arises from the fact that DNA barcodes in DEL libraries encode synthetic routes rather than chemical structures. This intricacy often leads to challenges in identifying genuine actives\, primarily due to incomplete chemical transformations during encoding\, resulting in low validation rates. \n\n\n\nIn response\, we will present a novel strategy for DEL hit validation. We will elucidate our approach\, which prominently features on-DNA compound resynthesis\, mirroring the methods employed during initial library synthesis. This seamlessly integrates with subsequent hit validation endeavors by using highly sensitivity surface-based biosensing in combination with a novel assay format. We will illustrate affinity correlations between on-DNA and off-DNA compounds\, offer insights into assay development\, and emphasize the utilization of enhanced sensitivity to allow us to detect low-abundancy on-DNA compounds. We will describe a systematic framework for DEL hit validation\, enhancing the identification of genuine binders with unwavering confidence and heightened sensitivity for drug discovery. \n\n\n\nSpeakers biography\n\n\n\nDr. Stefan Geschwindner is currently a Director at AstraZeneca R&D Gothenburg in Sweden where he is heading the Biophysics department within Discovery Sciences. He obtained his Ph.D. at the University of Frankfurt/Germany working predominantly with NMR to elucidate protein structures. After his Ph.D. he joined the Astra Structural Chemistry Laboratory with focus on protein engineering and characterization and helped to implement a variety of different biophysical methods and technologies in the early drug discovery process. Before moving into his current role\, he had different roles as Team leader in Protein Engineering and as Principal Scientist in Biophysics. His over 50 peer-reviewed publications are frequently cited leading to an h-index of 26.
URL:https://www.scilifelab.se/event/catalyzing-confidence-a-novel-strategy-for-enhancing-del-hit-validation-in-drug-discovery/
LOCATION:https://uu-se.zoom.us/j/65812174262
CATEGORIES:Event
ATTACH;FMTTYPE=image/jpeg:https://www.scilifelab.se/wp-content/uploads/2020/02/pills_600x200px.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20240516T141500
DTEND;TZID=Europe/Stockholm:20240516T163500
DTSTAMP:20260407T145459
CREATED:20240429T090516Z
LAST-MODIFIED:20240429T091240Z
UID:10001246-1715868900-1715877300@www.scilifelab.se
SUMMARY:Uppsala University DDLS Fellows - public seminars with candidates
DESCRIPTION:Welcome to a data driven-rich afternoon of scientific presentations by 4 candidates for the DDLS program fellow position on Data-driven Precision Medicine and Diagnostics and Biträdande Universitets Lektor position at Uppsala University. \n\n\n\nMeeting details\n\n\n\nMonday\, May 6\, 2024 14:15-16:35 \n\n\n\nZoom link >>   \n\n\n\nMötes-ID: 640 7985 9903 \n\n\n\nSchedule\n\n\n\n14:15-14:50     \n\n\n\nSergi Sayols Baixeras\, Uppsala University\, Dep. of Medical Sciences\, Sweden \n\n\n\nNovel Insights fromZMetagenomics and Metabolomics on Atherosclerotic Disease \n\n\n\n14:50-15:25      \n\n\n\nQiaoli Wang\, Harvard University Medical School\, Cambridge\, USA \n\n\n\nAnticipatory Detection of Upper-Gastrointestinal Cancers: Staying One Step Ahead with a Dash of Wit \n\n\n\n15:25-16:00      \n\n\n\nMuhammad Arif\, National Institute on Alcohol Abuse and Alcoholism\, Rockville\, USA \n\n\n\nIntegrative Multi-Omics Frameworks for Understanding the Molecular Mechanism of Progressive Diseases \n\n\n\n16:00-16:35      \n\n\n\nFilipe Barata\, Centre for Digital Health Interventions\, ETH Zurich\, Switzerland & Stanford University\, Palo Alto\, USA.  \n\n\n\nAdvancing Personalized Healthcare Through Digital Biomarkers
URL:https://www.scilifelab.se/event/uppsala-university-ddls-fellows-public-seminars-with-candidates/
CATEGORIES:Event
ORGANIZER;CN="SciLifeLab Event":MAILTO:events@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20240517T100000
DTEND;TZID=Europe/Stockholm:20240517T110000
DTSTAMP:20260407T145459
CREATED:20240311T123125Z
LAST-MODIFIED:20240311T123126Z
UID:10001199-1715940000-1715943600@www.scilifelab.se
SUMMARY:Digital twins and integrative systems biology
DESCRIPTION:NBIS\, Scilifelab’s Bioinformatics platform\, arranges an open AI and IO Seminar Series aimed at knowledge-sharing about Artificial Intelligence and Integrative Omics (AI & IO) analysis and applications in the Life Science community. The seminar series is open to everyone. The seminar is run over Zoom on the third Friday of the month during academic terms\, typically between 10 and 11 am\, with ca. 45 min long presentation and 15 min discussion. \n\n\n\nFor further info\, please see this website. \n\n\n\n \n\n\n\n\n\n\n\nDigital twins and integrative systems biology\n\n\n\nGunnar Cedersund\, Linköping University \n\n\n\nClick here to join zoom conference
URL:https://www.scilifelab.se/event/digital-twins-and-integrative-systems-biology/
LOCATION:Online event via Zoom
CATEGORIES:Event
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20240520T151500
DTEND;TZID=Europe/Stockholm:20240520T161500
DTSTAMP:20260407T145459
CREATED:20240409T150428Z
LAST-MODIFIED:20240409T150428Z
UID:10001213-1716218100-1716221700@www.scilifelab.se
SUMMARY:[The Svedberg seminar] - Multilevel drift and selection in the evolution of prokaryotic plasmids
DESCRIPTION:Tal Dagan \n\n\n\nProfessorInstitute of general microbiology\, Kiel University\, Germany. \n\n\n\n \n\n\n\n\n\n\n\nBio\n\n\n\nProf. Tal Dagan graduated her PhD in 2005 and moved to Germany for her postdoctoral studies. Since 2013 she is a professor of microbiology at Kiel University. Her main research interest is microbial genome evolution via lateral gene transfer with a focus on the evolution of prokaryotic plasmids \n\n\n\n \n\n\n\nMultilevel drift and selection in the evolution of prokaryotic plasmids\n\n\n\nPlasmids are an extrachromosomal genetic elements that populate prokaryote cells. Due to their interaction with a hosting cell\, drift and selection operate on plasmid alleles at two hierarchical levels: the collective of plasmids within the host and the collective of cells within the host population. The effect of these two levels on plasmid evolution remains understudied. Using experimental evolution approach integrated with phylogenomic reconstruction we found that: i) drift and selection at the level of the host population leads to contrasting effects on the plasmid fitness and ii) segregational drift of plasmid alleles during cell division constrains the rate of plasmid evolution. Our findings may apply for the evolution of other extrachromosomal genetic elements having a similar population structure. Focusing on plasmids\, our research thus uncovers general principles in the evolution of autonomously replicating genetic elements. \n\n\n\n \n\n\n\n\n\n\n\nHost: Maliheh Mehrshad maliheh.mehrshad@slu.se\, SLU and Helen Wang helen.wang@imbim.uu.se  UU
URL:https://www.scilifelab.se/event/the-svedberg-seminar-tal-dagan/
LOCATION:BMC Room C8:301\, Husargatan 3\, Uppsala\, Sweden
CATEGORIES:Event
ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2022/02/Picture1-The-Svedberg.png
ORGANIZER;CN="The Svedberg Seminar Series":MAILTO:thesvedberg@scilifelab.uu.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20240521T103000
DTEND;TZID=Europe/Stockholm:20240521T120000
DTSTAMP:20260407T145459
CREATED:20240515T074909Z
LAST-MODIFIED:20240515T074909Z
UID:10001259-1716287400-1716292800@www.scilifelab.se
SUMMARY:Uppsala University DDLS Fellows - public seminars with candidates - part II
DESCRIPTION:Welcome to the second data driven-rich morning of scientific presentations by 2 candidates for the DDLS program fellow position on Data-driven Precision Medicine and Diagnostics and Biträdande Universitets Lektor position at Uppsala University. \n\n\n\nSchedule \n\n\n\nMeeting details\n\n\n\nTuesday\, May 21\, 2024 10:30-12:00 \n\n\n\nZoom link >>   \n\n\n\nMötes-ID: 663 2681 5420 \n\n\n\nSchedule\n\n\n\n10:30-11:05     \n\n\n\nMarcel Tarbier\, Karolinska Institutet\, Stockholm\, Sweden \n\n\n\nInto the Single-Verse: Inferring complex gene and cell features from gene expression – and an excursion through space and time \n\n\n\n11:05-11:40      \n\n\n\nMuhammad Arif\, National Institute on Alcohol Abuse and Alcoholism\, Rockville\, USA \n\n\n\nIntegrative Multi-Omics Frameworks for Understanding the Molecular Mechanism of Progressive Diseases
URL:https://www.scilifelab.se/event/uppsala-university-ddls-fellows-public-seminars-with-candidates-part-ii/
CATEGORIES:Event
ORGANIZER;CN="SciLifeLab Event":MAILTO:events@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20240521T120000
DTEND;TZID=Europe/Stockholm:20240521T130000
DTSTAMP:20260407T145459
CREATED:20240507T095644Z
LAST-MODIFIED:20240507T100517Z
UID:10001256-1716292800-1716296400@www.scilifelab.se
SUMMARY:3D/4D X-ray Microtomography: Insight into materials critical for the green transition
DESCRIPTION:In the frame of the “SciLifeLab Site Umeå / KBC Infrastructure Seminar Series”\, the seminars will be organised every second Tuesday during spring 2024. The seminars will be held in a hybrid format – IRL in Glasburen\, KBC\, Umeå\, and online via Zoom. \n\n\n\nRead more about the Seminar Series\n\n\n\nOn 21 May\, at 12:00\, SciLifeLab Site Umeå / KBC Infrastructure Seminar Series presents: \n\n\n\n3D/4D X-ray Microtomography: Insight into materials critical for the green transition\n\n\n\nPresenter: Fredrik Forsberg\, Senior Lecturer\, Luleå University of Technology\, Div. Fluid and Experimental Mechanics \n\n\n\nDescription: A seminar about high-resolution x-ray microtomography (XCT) and how it can be used for 3D/4D material and process characterisation to support the green transition. During the seminar selected applications will be presented from studies at the X-ray Microtomography Lab at LTU (using a Zeiss Xradia 620 Versa XRM) and using synchrotron tomography. For example\, studies of modified wood for increased moisture resistance\, studies on hydrogen and CO2 storage in porous bedrock\, and studies of minerals critical for the green transition. The seminar ends with a look at future possibilities with Dynamic and Spectral XCT – a new XCT system that soon will be available at LTU. \n\n\n\nRead more and Register
URL:https://www.scilifelab.se/event/3d-4d-x-ray-microtomography-insight-into-materials-critical-for-the-green-transition/
CATEGORIES:Event
ATTACH;FMTTYPE=image/jpeg:https://www.scilifelab.se/wp-content/uploads/2024/05/SciLifeLab-Site-Umea-seminar-scaled.jpg
ORGANIZER;CN="SciLifeLab Ume%C3%A5":MAILTO:umea@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20240521T150000
DTEND;TZID=Europe/Stockholm:20240521T160000
DTSTAMP:20260407T145459
CREATED:20240426T121443Z
LAST-MODIFIED:20240513T043915Z
UID:10001242-1716303600-1716307200@www.scilifelab.se
SUMMARY:Architecture of Active Human Enhancers and Molecular Features That Drive\, Long-Range\, Highly-regulated Transcription
DESCRIPTION:Campus Solna Spotlight Seminar series welcomes Professor John Lis from Cornell university to Stockholm to present his outstanding work. \n\n\n\nJohn Lis is a Professor in the Department of Molecular Biology and Genetics. He did his graduate research at Brandeis University and received his Ph.D. in Biochemistry in 1975. His postdoctoral work focused on Drosophila gene regulation and chromosome structure at Stanford University\, during which time he was supported by a fellowship from the Helen Hay Whitney Foundation. Dr. Lis joined the faculty at Cornell in 1978. His research program has been supported by the National Institutes of Health\, including a MERIT Award\, March of Dimes\, American Cancer Society\, Cornell Biotechnology Institute\, and a Proctor and Gamble University Exploratory Research Grant. \n\n\n\nAbstract\n\n\n\nMechanisms of Transcriptional Regulation of Drosophila & Mammalian Genomes \n\n\n\nTranscription by RNA Polymerase II (Pol II)\, the enzyme responsible for all mRNA synthesis\, is highly regulated by protein factors at multiple steps in the transcription cycle. Two critical regulatory steps\, whose regulatory integration is critical for the sophisticated gene regulation seen in multicellular eukaryotes\, are 1) the recruitment of Pol II to promoters where it rapidly initiates transcription and can enter into a promoter-proximal\, paused state 20-50 base pairs from the initiation site; and 2) the release of paused Pol II into productive elongation. Promoter-proximal pausing is dependent on protein complexes DSIF (DRB Sensitivity Inducing Factor) and NELF (Negative Elongation Factor) bind to Pol II early in transcription to stabilize pausing. Pause release occurs upon phosphorylation of Pol II\, DSIF and NELF by the Cdk9\, Cyclin T1 heterodimer P-TEFb (Positive Transcription Elongation Factor b). Several elongation factors\, e.g.\, PAF1 and Spt6\, engage with Pol II in its transition from its promoter-proximal pause to productive elongation. Although Pol II pausing is a key step in transcription regulation and has been extensively studied\, the molecular mechanisms of pausing and pause release to productive elongation are far from being completely understood. Furthermore\, recent studies have led to competing molecular mechanisms on the role of promoter-proximal pausing in the control of transcription. In this seminar\, I will describe the evolution of our understanding of transcription regulation as well as describe our latest efforts to advance and resolve this understanding using a variety of state-of-the-art genomic and optical methods in Drosophila and mammals.
URL:https://www.scilifelab.se/event/architecture-of-active-human-enhancers-and-molecular-features-that-drive-long-range-highly-regulated-transcription/
LOCATION:Air&Fire\, SciLifeLab Stockholm\, Tomtebodavägen 23A\, Solna\, Sweden
CATEGORIES:Event
ATTACH;FMTTYPE=image/jpeg:https://www.scilifelab.se/wp-content/uploads/2023/10/Campus-solna-seminar-picture.jpg
ORGANIZER;CN="Spotlight Seminar Series":MAILTO:events@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20240522T090000
DTEND;TZID=Europe/Stockholm:20240522T173000
DTSTAMP:20260407T145459
CREATED:20240503T110350Z
LAST-MODIFIED:20240503T110351Z
UID:10001250-1716368400-1716399000@www.scilifelab.se
SUMMARY:Karolinska Institutet - SciLifeLab Symposium
DESCRIPTION:Welcome to the joint KI-SciLifeLab symposium\, with the goal to foster and highlight the exciting science going on at KI and SciLifeLab\, featuring popular science writer and journalist Karin Bojs\, exciting science talks by Drs. Anna Wedell\, Maria Kasper\, Kasper Karlsson\, Oscar Fernandez-Capetillo\, our very own SciLifeLab trainees\, and more! The day will finish with a poster/mingle session at SciLifeLab where you can discuss science over drinks and snacks.   \n\n\n\nIt will be an exciting day !   \n\n\n\nRead more and Register here
URL:https://www.scilifelab.se/event/karolinska-institutet-scilifelab-symposium/
LOCATION:Jacob Berzelius salen\, KI\, Berzelius väg 3\, Solna\, 171 65\, Sweden
CATEGORIES:Event
ORGANIZER;CN="Other events by SciLifeLab Committee at KI":MAILTO:adina.feldman@ki.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20240522T151500
DTEND;TZID=Europe/Stockholm:20240522T161500
DTSTAMP:20260407T145459
CREATED:20240503T151406Z
LAST-MODIFIED:20240503T151408Z
UID:10001252-1716390900-1716394500@www.scilifelab.se
SUMMARY:[The Svedberg seminar] Mechanisms of Transcriptional Regulation of Drosophila & Mammalian Genomes
DESCRIPTION:John Lis \n\n\n\nProfessor of Molecular Biology and GeneticsCornell  University\, USA \n\n\n\n \n\n\n\n\n\n\n\nBio\n\n\n\nDr\, Lis received his B.S degree in Chemistry from Fairfield University\, and his Ph.D. in Biochemistry from Brandeis University. His postdoctoral work at Stanford University focused on molecular genetics and was supported by a Helen Hay Whitney Foundation Fellowship. Dr. Lis joined the faculty at Cornell in 1978 and served as Chairman of the Section of Biochemistry\, Molecular & Cell Biology in the 1990s. He is now the Barbara McClintock Professor of Molecular Biology and Genetics and a member of the American Academy of Arts and Sciences and the National Academy of Sciences. Dr. Lis’ group develops new approaches to study the molecular mechanisms of transcription regulation\, and he uses these newly developed and existing technologies in both focused studies of highly-regulated genes and in comprehensive analyses of gene regulation of Drosophila and human genomes. A Harvey Lecture at Rockefeller University summarizes some of his past work that can be accessed using the following link. https://harveysociety.org/videos/video.php?series=114&lecture=1&wvideo=7810nzrdc0 \n\n\n\n \n\n\n\nMechanisms of Transcriptional Regulation of Drosophila & Mammalian Genomes \n\n\n\nTranscription by RNA Polymerase II (Pol II)\, the enzyme responsible for all mRNA synthesis\, is highly regulated by protein factors at multiple steps in the transcription cycle. Two critical regulatory steps\, whose regulatory integration is critical for the sophisticated gene regulation seen in multicellular eukaryotes\, are 1) the recruitment of Pol II to promoters where it rapidly initiates transcription and can enter into a promoter-proximal\, paused state 20-50 base pairs from the initiation site; and 2) the release of paused Pol II into productive elongation. Promoter-proximal pausing is dependent on protein complexes DSIF (DRB Sensitivity Inducing Factor) and NELF (Negative Elongation Factor) bind to Pol II early in transcription to stabilize pausing. Pause release occurs upon phosphorylation of Pol II\, DSIF and NELF by the Cdk9\, Cyclin T1 heterodimer P-TEFb (Positive Transcription Elongation Factor b). Several elongation factors\, e.g.\, PAF1 and Spt6\, engage with Pol II in its transition from its promoter-proximal pause to productive elongation. Although Pol II pausing is a key step in transcription regulation and has been extensively studied\, the molecular mechanisms of pausing and pause release to productive elongation are far from being completely understood. Furthermore\, recent studies have led to competing molecular mechanisms on the role of promoter-proximal pausing in the control of transcription. In this seminar\, I will describe the evolution of our understanding of transcription regulation as well as describe our latest efforts to advance and resolve this understanding using a variety of state-of-the-art genomic and optical methods in Drosophila and mammals \n\n\n\n \n\n\n\n\n\n\n\nHost: Anniina Vihervaara anniina.vihervaara@scilifelab.se
URL:https://www.scilifelab.se/event/the-svedberg-seminar-john-lis/
LOCATION:BMC Room C8:301\, Husargatan 3\, Uppsala\, Sweden
CATEGORIES:Event
ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2022/02/Picture1-The-Svedberg.png
ORGANIZER;CN="The Svedberg Seminar Series":MAILTO:thesvedberg@scilifelab.uu.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20240522T160000
DTEND;TZID=Europe/Stockholm:20240522T170000
DTSTAMP:20260407T145459
CREATED:20240402T112908Z
LAST-MODIFIED:20240402T112910Z
UID:10001223-1716393600-1716397200@www.scilifelab.se
SUMMARY:Insights into Human Atherosclerosis using novel tools for Spatial biology
DESCRIPTION:Sikander Hayat\, Translational Data Science\, Uniklinik Aachen \n\n\n\nInsights into Human Atherosclerosis using novel tools for Spatial biology \n\n\n\nSingle-cell and spatial technologies are paving the way to understand human health\, disease and aging at unprecedented resolution. How can we best leverage diverse multi-omics data to generate testable hypothesis and contribute to developing optimal precision therapies and biomarkers for human disease conditions? \n\n\n\nHayat lab is a new and interdisciplinary computational lab at the Institute of Experimental Medicine and Systems Biology\, UniKlinik Aachen. Our group focuses on developing computational tools for systematically analyzing\, interpreting and visualizing data from single-cell technologies such as single-cell transcriptomics\, spatial transcriptomics and high-content imaging. \n\n\n\nA key theme in our lab is to develop scalable and efficient tools to leverage data from millions of single-cells to understand disease\, health and aging. Some of the research areas we are working on include:   \n\n\n\n\nIdentifying novel targets and biomarkers for fibrosis in kidney and heart\,\n\n\n\nUnderstand mechanisms of heart failure at single-cell resolution\,\n\n\n\nElucidate processes involved in aging at single-cell resolution\,\n\n\n\nPrioritize high-impact mutations in cardio-renal disease\,\n\n\n\nDevelop tools for automated cell-type annotation\, multi-omics data integration\, and interactive data visualization\n\n\n\n\nWe work in very close collaboration with medical doctors and experimentalists in the Krammanlab (www.kramannlab.com) at UniKlinik RWTH Aachen.
URL:https://www.scilifelab.se/event/insights-into-human-atherosclerosis-using-novel-tools-for-spatial-biology/
LOCATION:Air&Fire\, SciLifeLab Stockholm\, Tomtebodavägen 23A\, Solna\, Sweden
CATEGORIES:Event
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20240524T090000
DTEND;TZID=Europe/Stockholm:20240524T093000
DTSTAMP:20260407T145459
CREATED:20240130T123401Z
LAST-MODIFIED:20240311T091702Z
UID:10001132-1716541200-1716543000@www.scilifelab.se
SUMMARY:To solve the unsolved and phenotype the solved rare diseases
DESCRIPTION:Ann Nordgren\, Karolinska Institutet \n\n\n\n \n\n\n\nregistration\n\n\n\nClinical Talks \n\n\n\nClinical Talks is an educational seminar series open to everyone. It is organized by the SciLifeLab Precision Medicine Capability\, and invites a mixture of speakers that are experts with a clinical perspective on topics concerning rare diseases\, cancer\, microbiology and bioinformatics. \n\n\n\nHealth is individual and patients can benefit greatly from personalized treatments\, tailored for their specific molecular disposition. This rapidly emerging field\, known as Precision Medicine\, relies on technology development and requires close collaboration between scientists and healthcare professionals. SciLifeLab aims to bring cutting-edge technologies\, first-class expertise and data infrastructure to build the foundation of tomorrow’s Precision Medicine.
URL:https://www.scilifelab.se/event/rare-diseases/
LOCATION:Online event via Zoom
CATEGORIES:Event
ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2024/01/Clinical-Talks-sq.png
ORGANIZER;CN="Clinical Talks":MAILTO:precisionmedicine@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20240527T151500
DTEND;TZID=Europe/Stockholm:20240527T161500
DTSTAMP:20260407T145459
CREATED:20240515T140213Z
LAST-MODIFIED:20240515T140214Z
UID:10001261-1716822900-1716826500@www.scilifelab.se
SUMMARY:[The Svedberg seminar] - Following spatial and temporal chemical changes in neurobiology
DESCRIPTION:Wojciech Michno \n\n\n\nAssistant Professor\, SciLifeLab FellowUppsala University \n\n\n\n \n\n\n\n\n\n\n\nBio\n\n\n\nWojciech Michno is a neurochemistry researcher whose work focuses on studying spatial and temporal chemical changes in the brain to aid the understanding of neurological diseases. He obtained his PhD at the University of Gothenburg\, followed by three years as a postdoctoral researcher\, at University College London\, and Stanford University\, before joining the Department of Public Health and Caring Sciences\, at Uppsala University. His group works at the intersection of stem cell biology and analytical chemistry\, to understand how pathology-related local microenvironments and cell-specific phenotype changes contribute to the development and progression of neurological diseases\, such as neurodegeneration and cancer. \n\n\n\n \n\n\n\nFollowing spatial and temporal chemical changes in neurobiology\n\n\n\n \n\n\n\nUnderstanding “What’s happening in the human brain”\, has always been challenging. For a long time\, this has hampered our strategies to address diverse neurological conditions ranging from neurodevelopment to neurodegeneration\, but also cancer. Yet recent advances in stem cell-derived complex 3D models of the brain\, genetic engineering\, and state-of-the-art molecular and chemical imaging techniques open a new path to understanding the human brain. These approaches allow us to not only capture the end stages of diseases such as Alzheimer’s disease but also follow them over time. For the first time\, we can study the cellular phenotypes associated with cell-specific interactions from the spatial as well as temporal standpoint. This allows us to understand both the short- and the long-term consequences of genetically or environmentally induced insults to brain homeostasis.  \n\n\n\nIn this talk\, I will present some of the work related to revisiting the core of neuropathological changes associated with Alzheimer’s disease\, and how chemical imaging techniques can be leveraged to understand the previously inaccessible events in the pathology development. I will also address opportunities and limitations of combining cutting-edge stem cell biology and chemistry\, in studying the mechanism underlying environmentally associated pathological changes in Alzheimer’s disease and beyond. \n\n\n\n \n\n\n\n \n\n\n\n\n\n\n\nHost: Stina Syvänen stina.syvanen@pubcare.uu.se
URL:https://www.scilifelab.se/event/the-svedberg-seminar-wojciech-michno/
LOCATION:BMC Room C8:305
CATEGORIES:Event
ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2022/02/Picture1-The-Svedberg.png
END:VEVENT
END:VCALENDAR