Inaugural Sjöstrand Lecture in structural biology by Venki Ramakrishnan

Venki Ramakrishnan will give the lecture entitled ’Termination of translation in bacteria and eukaryotes’ on Monday 27th August 2018 at 4.00pm in the Biomedicum Lecture Theatre.

The annual lecture series is set up in the recognition of Fritiof Sjöstrand’s contribution to the development of electron microscopy and will be delivered by eminent scientists in the field. The event is organised by SciLifeLab, Karolinska Institutet and the Journal of Structural Biology and open to anyone. A holder of the lectureship will particularly spend time with students and postdocs.

Venki will give an account of his career path and discuss with students and postdocs at 10.00am in the SciLifeLab Air&Fire auditorium. Since the number of places is limited, please register here to participate in this session.

About Venki Ramakrishnan

Research in Ramakrishnan’s laboratory is aimed at understanding the molecular mechanism of protein synthesis. His lab was the first to determine atomic structures of the ribosome in different functional states and in complexes with several antibiotics. More recently, he has been using cryo-EM to visualise ribosomes in action in higher organisms. This work has yielded fundamental biological insights into how the genetic information is read to synthesise proteins from amino acids.

Venki received the Nobel Prize in Chemistry for his work on ribosomal structure and was knighted in 2012. In 2015, he was elected as President of the Royal Society.

Background information

The annual lecture in structural biology is named in honour of Fritiof Sjöstrand, who pioneered the electron microscopy in Sweden in the 1950’s.

Fritiof Sjöstrand was born in Stockholm in 1912. He studied medicine in Karolisnka Institutet, and became engaged in research on biological applications of electron microscopy. In 1943 he recorded skeletal muscle fibres for the first time. In the early 1950’s Fritiof developed an advanced microtome for thin sectioning and by applying it for structural analysis of mitochondria produced a major breakthrough with the determination of the double membrane system. He then engineered a next generation of microtomes using electrical heating of the specimen to advance it toward the knife. This instrument became known as the ‘‘Sjöstrand Ultramicrotome”, and about 500 units were sold worldwide. In 1959 he moved to UCLA, where his research focused on mitochondrial membranes and retinal synapses. Fritiof Sjöstrand founded and was Editor in Chief of the Journal of Structural Biology for 33 years.

Contact person
: Alexey Amunts,