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BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220502T080000
DTEND;TZID=Europe/Stockholm:20220506T170000
DTSTAMP:20260404T065701
CREATED:20220224T100439Z
LAST-MODIFIED:20220224T131919Z
UID:10000535-1651478400-1651856400@www.scilifelab.se
SUMMARY:Spatial analysis of gene expression in tissues
DESCRIPTION:Single-cell genomics technologies have become widely used to study heterogeneous and dynamic biological systems. In order to meet the growing demand for a deeper understanding of tissue profiling\, a number of different spatial transcriptomics approaches have been developed and applied successfully. \n\n\n\nThe goal of this practical course is to provide participants with an overview of the different spatially resolved transcriptome mapping techniques\, learn about the differences and advantages of each technique\, and how to choose and employ the techniques when designing their study. \n\n\n\nThe course includes practical work with hands-on wet-lab work and imaging sessions as well as primary data analysis for three technologies in two practical formats: Visium/Spatial Transcriptomics (ST) as an unbiased method\, and In Situ Sequencing (ISS)/Scrinshot as targeted methods. \n\n\n\nThe lectures will cover the following topics: Visium/ST\, ISS/Scrinshot\, osmFISH\, seqFISH+\, Slide-seqV2\, MERFISH\, CellPhoneDB as well as Human Cell Atlas. \n\n\n\nThe course is aimed at the graduate student and postdoctoral level\, but applications from scientists at all levels are welcome.Registration deadline: 18 March \n\n\n\nRead more and register\n\n\n\n\n\n\n\nCourse Flyer
URL:https://www.scilifelab.se/event/spatial-analysis-of-gene-expression-in-tissues/
LOCATION:Air&Fire\, SciLifeLab Stockholm\, Tomtebodavägen 23A\, Solna\, Sweden
CATEGORIES:Course
ORGANIZER;CN="Joakim Lundeberg":MAILTO:joakim.lundeberg@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220502T151500
DTEND;TZID=Europe/Stockholm:20220502T161500
DTSTAMP:20260404T065701
CREATED:20220422T104856Z
LAST-MODIFIED:20220422T111337Z
UID:10000590-1651504500-1651508100@www.scilifelab.se
SUMMARY:The use of systems biology in treatment of liver diseases
DESCRIPTION:Adil Mardinoglu\, Assoc. Prof.KTH SwendenKing s College London\, UK\n\n\n\n \n\n\n\nRegister here to get the zoom link\n\n\n\nAssoc. Prof. Adil Mardinoglu is an expert in the field of Systems Medicine\, Systems Biology\, Computational Biology and Bioinformatics. He lead a team of 25 researchers working in the area of computational biology\, experimental biology and drug development to develop new treatment strategies for Metabolic diseases\, Neurodegenerative diseases and certain type of cancers  \n\n\n\n Abstract: Biological networks can provide a scaffold for studying biological pathways operating in the liver in connection with disease development in a systematic manner. In my presentation\, I will present our recent work where biological networks have been employed to identify the reprogramming in liver physiology in response to NASH/NAFLD. I will further discuss how this mechanistic modelling approach can contribute to the discovery of biomarkers and identification of drug targets which may lead to design of targeted and effective personalized medicine. \n\n\n\nWebpage: https://sysmedicine.com/
URL:https://www.scilifelab.se/event/adil-mardinoglu/
LOCATION:Online event via Zoom
CATEGORIES:Event
ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2022/02/Picture1-The-Svedberg.png
ORGANIZER;CN="The Svedberg Seminar Series":MAILTO:thesvedberg@scilifelab.uu.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220503T090000
DTEND;TZID=Europe/Stockholm:20220503T120000
DTSTAMP:20260404T065701
CREATED:20220121T160156Z
LAST-MODIFIED:20220121T160157Z
UID:10000514-1651568400-1651579200@www.scilifelab.se
SUMMARY:BioImage Analysis support - Call4Help
DESCRIPTION:Every 1st week of the month (mainly on Tuesdays\, but there might be exceptions) the BioImage Informatics Facility together with microscopy expert Sylvie Le Guyader (LCI\, Karolinska Institutet) organizes a Call4Help session. The aim is to offer combined expertise towards microscopy and bioimage analysis. All researchers from Swedish institutes can participate. \n\n\n\nThe ideal timepoint to join the Call4Help session is when a researcher has performed pilot experiments and has tried out first analysis approaches – but before having recorded hundreds of images. Combining BIIF’s expertise in BioImage Analysis with microscopy expertise we can discuss ways to record the images that allow analysis afterwards. We will discuss different analysis approaches using mainly open-source software (Fiji\, CellProfiler\, QuPath\, Ilastik\, KNIME)\, but also commercial systems\, if needed (Imaris). \n\n\n\nThe Call4Help session format has been introduced to the BioImage Analysis community by NEUBIAS and ScopeM. \n\n\n\nHow to participate? \n\n\n\nStep1: \n\n\n\nPrepare a short presentation (5-7 min)  – use the following template for your presentation: \n\n\n\nhttp://bit.ly/BIIF_C4H_slideTemplate \n\n\n\nSlide template by NEUBIAS/ScopeM \n\n\n\nStep2: \n\n\n\na) Upload your presentation \n\n\n\nUpload your presentation to a drive of your choice. You can also use our Call4Help google drive. Note that files shared on our Call4Help drive will be available to everyone until the session is over. \n\n\n\nhttp://bit.ly/BIIF_C4H_Drive \n\n\n\nb) Upload example images for testing. \n\n\n\nUpload example images for testing either to the drive of your choice or our Call4Help google drive above. \n\n\n\nhttp://bit.ly/BIIF_C4H_Drive \n\n\n\nc) Register by filling out the registration form: \n\n\n\nhttp://bit.ly/BIIF_C4H_Registration \n\n\n\nStep 3: \n\n\n\nJoin the zoom-session. \n\n\n\nIf your problem is selected for presentation\, you will get a time-slot of 30 – 60 minutes within the session. \n\n\n\nWhat are the Deadlines \n\n\n\nSubmission of a problem and upload of example data: Friday the week before the session. \n\n\n\nNotification about participation: The day before the session. \n\n\n\nNext Call4Help session \n\n\n\nTuesday\, May 3\, 2022\, 9.00-12.00. Deadline for application: Friday\, April 29\, 2022.
URL:https://www.scilifelab.se/event/bioimage-analysis-support-call4help-4/
LOCATION:Online event via Zoom
CATEGORIES:Event
ORGANIZER;CN="Bioimage Informatics Unit":MAILTO:biif@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220504T120000
DTEND;TZID=Europe/Stockholm:20220504T130000
DTSTAMP:20260404T065701
CREATED:20220503T132158Z
LAST-MODIFIED:20220503T132207Z
UID:10000600-1651665600-1651669200@www.scilifelab.se
SUMMARY:Campus Solna Seminar: Karl Olofson
DESCRIPTION:Welcome to the Campus Solna Seminar Series – an initiative to promote the fantastic science ongoing at Campus Solna and hopefully forge more internal communication and collaboration between the alpha and gamma buildings. The format will be 2 short 15 min talks (1 speaker from alpha and 1 from gamma)\, with an additional 5 min of questions. Presentation of ongoing (unpublished) projects is strongly encouraged. \n\n\n\nThe seminars are held Thursdays 12:00-12:50 and in Air&Fire\, SciLifeLab Stockholm. \n\n\n\n\n\n\nKarl Olofson\n\n\n\n \n\n\n\nMartin Viklund/Björn Önfelt\, gamma 3 \n\n\n\nUltrasound-based particle manipulation in microcavities.
URL:https://www.scilifelab.se/event/campus-solna-seminar-karl-olofson/
LOCATION:Air&Fire\, SciLifeLab Stockholm\, Tomtebodavägen 23A\, Solna\, Sweden
CATEGORIES:Community
ORGANIZER;CN="SciLifeLab Solna PhD & Postdoc Council":MAILTO:phd-council@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220505T130000
DTEND;TZID=Europe/Stockholm:20220505T170000
DTSTAMP:20260404T065701
CREATED:20211202T101312Z
LAST-MODIFIED:20220504T152450Z
UID:10000495-1651755600-1651770000@www.scilifelab.se
SUMMARY:γδSTO workshop -  Mini-symposium of Stockholm’s γδ T cell community
DESCRIPTION:A workshop on the May 5\, on gamma delta T cells for our scientific community in Stockholm. Different labs from SciLifeLab\, KI (Solna and Fleminsberg) and Stockholm University are invited. \n\n\n\nregister to attend\n\n\n\nProgram: \n\n\n\nγδSTO-workshop-programDownload
URL:https://www.scilifelab.se/event/%ce%b3%ce%b4sto-workshop/
LOCATION:Air&Fire\, SciLifeLab Stockholm\, Tomtebodavägen 23A\, Solna\, Sweden
CATEGORIES:Community,Event
ORGANIZER;CN="Patrick Sandoz":MAILTO:patrick.sandoz@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220505T150000
DTEND;TZID=Europe/Stockholm:20220505T160000
DTSTAMP:20260404T065701
CREATED:20220428T154038Z
LAST-MODIFIED:20220428T154048Z
UID:10000597-1651762800-1651766400@www.scilifelab.se
SUMMARY:BAM Seminar: From memes to wordplay – How to add humor to your science communication
DESCRIPTION:‘First make people laugh\, and then make them think’. Humor can be a powerful way to attract attention and convey your message. However\, it is also challenging to find the right balance between funny quips and scientific content. In this talk\, Jente Ottenburghs will share some tips and tricks on how he has managed to blend stand-up comedy and science communication. \n\n\n\nJente Ottenburghs\, is a lecturer at University of Wageningen. He worked as a Postdoc at Karolinska Institutet and Uppsala University after he obtained his PhD from University of Wageningen. Throughout his career\, he experimented with different ways of Science communication and also did stand-up comedy.  \n\n\n\nResearchers in all stages of their career\, who want to spice up their talks\, are welcome to attend and could find the talk useful. Branching out in the ways to present one’s research can make talks more interesting and memorable and can help to convey the messages to the audience.  
URL:https://www.scilifelab.se/event/from-memes-to-wordplay-how-to-add-humor-to-your-science-communication/
LOCATION:Online event via Zoom
CATEGORIES:Event
ORGANIZER;CN="SciLifeLab Solna PhD & Postdoc Council":MAILTO:phd-council@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220506T090000
DTEND;TZID=Europe/Stockholm:20220506T093000
DTSTAMP:20260404T065701
CREATED:20220217T115711Z
LAST-MODIFIED:20220331T141218Z
UID:10000531-1651827600-1651829400@www.scilifelab.se
SUMMARY:[Clinical Talks] iCAN and developing a national precision cancer medicine program
DESCRIPTION:On May 6\, Professor Tomi Mäkelä at the University of Helsinki Faculty of Medicine will talk about his work as executive officer of the iCAN Digital Precision Cancer Medicine flagship. iCAN is one of the Academy of Finland national research and innovation flagships for 2019-2026\, with the goal to develop a nucleus of scientific excellence into competence clusters for discoveries\, innovations\, and societal and economic impact. The founding hosts are the University of Helsinki and HUS Helsinki University Hospital with a goal for national reach within the National Cancer Center FICAN. While executed as a public-private-patient-partnership\, iCAN brings together academic research\, healthcare system\, life science industry partners and patients. The active participation of patients at all levels is a key element of the flagship\, ensuring impact and benefits to the patients. Partnerships with companies from pharma\, biotech\, and AI sectors are critical and enable the inclusion of early drug leads\, new technologies\, and new competencies. Furthermore\, iCAN leverages the unique strengths that Finland has in the areas of top-level cancer research\, health registries\, biobanks\, and digital health to provide solutions for the global cancer challenge. \n\n\n\nRegistration\n\n\n\nTomi Mäkelä\, MD\, PhD\, is a Professor of Biochemistry and Molecular Biology at the University of Helsinki Faculty of Medicine\, and the Executive Officer of the Finish iCAN Digital Precision Cancer Medicine flagship program. He obtained an MD and PhD in Oncology and Cancer Biology during his studies in the late 80\, early 90s at the University of Helsinki. He then pursued his postdoctoral studies at the prestigious Whitehead Institute\, Cambridge Massachusetts 1993-1995\, and in 2002 became a Professor at the University of Helsinki. Since\, then he has held various leadership positions at the University\, including\, Director of the Institute of Biotechnology (2009-2014)\, Director of HiLIFE Helsiniki Institute of Life Science (2015-2019)\, Director of Biomedicum Helsinki (2017-present). Prof. Mäkelä is also the current Executive Manager of The Finnish Cancer Institute (since 2012)\, and a panelist and panel chair of the European Research Council since 2011. \n\n\n\nThe iCAN Digital Precision Cancer Medicine flagship is one of six national flagships in Finland 2019-2026 aiming to develop nuclei of scientific excellence into competence clusters for discoveries\, innovations\, and societal and economic impact. In iCAN a platform joining Precision Cancer Medicine (PCM) with Digital Health is established for discoveries and improved treatments. iCAN is hosted by the University of Helsinki and Helsinki University Hospital HUS and with a goal for national reach within the National Cancer Center FICAN. Leveraging the unique strengths that Finland has in the areas of top-level cancer research\, health registries\, biobanks\, and digital health to provide solutions for the global cancer challenge. iCAN is furthermore organized as a partnership between academic research\, healthcare system\, life science industry partners and patients. It is a public-private-patient-partnership\, forming a competence cluster with significant economic\, educational\, and societal impact. The active participation of patients at all levels is a key element of the flagship\, ensuring impact and benefits to the patients. Partnerships with companies from pharma\, biotech\, and AI sectors are critical and enable the inclusion of early drug leads\, new technologies\, and new competencies. \n\n\n\nThese ambitious goals are accomplished via the unique iCAN digital precision cancer medicine platform\, enabling the integration of cutting-edge molecular profiling information from tumors with rich longitudinal health data available in Finland\, by eg. addressing tumor development in the context of the immune system or development of treatment resistance. The iCAN discovery platform links molecular profiling of tumors with broader health data of cancer patients\, acting as a catalyst for breakthrough research and technologies.The scale of data – 15\,000 samples across different cancer types will be profiled by 2026 – enables real impact and broad studies across different cancer types. The platform will enable an improved understanding of the complex interplay between cancer cells and the host.The pan-cancer research project already has ongoing studies in colorectal\, gastric\, pancreatic\, breast\, lung\, ovarian\, renal\, prostate\, bladder\, melanoma\, and pediatric solid cancers as well as myeloid leukemias\, lymphomas and multiple myeloma. \n\n\n\nRead more\n\n\n\n\n\n\n\n\n“Clinical Talks” has been renewed for yet another exciting\, innovative\, and enlightening season. This season will focus on sustainable innovations within Life Sciences\, that have the potential to contribute to a better climate friendly future for our future generations. Also new this year is that the seminar is co-organized in a collaboration between SciLifeLab and KI Innovations . \n\n\n\nSeason 5\, will be held September 2021 until March 2022 with scheduled Talks\, during Friday mornings 09-09:30 am via ZOOM (with some time-zone friendly adjustments for our international speakers). Each session consists of a talk given by our invited speaker followed by Q&A. The seminar is an open educational seminar series for our ever-expanding Life Science community.
URL:https://www.scilifelab.se/event/clinical-talks-ican-and-developing-a-national-precision-cancer-medicine-program/
LOCATION:Online event via Zoom
CATEGORIES:Event
ORGANIZER;CN="Clinical Talks":MAILTO:precisionmedicine@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220509T090000
DTEND;TZID=Europe/Stockholm:20220509T110000
DTSTAMP:20260404T065701
CREATED:20220315T124100Z
LAST-MODIFIED:20220715T121447Z
UID:10000554-1652086800-1652094000@www.scilifelab.se
SUMMARY:Open science & Reproducibility Services at SciLifeLab
DESCRIPTION:Time: 09:00-11:00Format: Zoom meeting will be recorded \n\n\n\nSciLifeLab Data Centre invites you to a 2-hour event on May 9th 2022 focusing on services available at SciLifeLab for researchers regarding Open Science and Reproducibility.  \n\n\n\nIn the event we will showcase a variety of tools and services to facilitate open and reproducible practices in data-driven research.  \n\n\n\nSpeakers: \n\n\n\nErik Fasterius\, NBISStephan Nylinder\, NBIS Data Management teamAnna Asklöf\, SciLifeLab Data Centre teamOla Spjuth\, prof.\, SciLifeLab\n\n\n\n\n\n\n\nRegister here\n\n\n\n\n\n\n\nDon’t forget to register to the afternoon event: \n\n\n\nexploring Open Science Pathways in the Earth\, Space\, and Life Sciences
URL:https://www.scilifelab.se/event/open-science-reproducibility-at-scilifelab/
LOCATION:Online event via Zoom
CATEGORIES:Event
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220509T120000
DTEND;TZID=Europe/Stockholm:20220509T170000
DTSTAMP:20260404T065701
CREATED:20220315T080000Z
LAST-MODIFIED:20220509T065057Z
UID:10000552-1652097600-1652115600@www.scilifelab.se
SUMMARY:Open Science Pathways in the Earth\, Space\, and Life Sciences
DESCRIPTION:SciLifeLab Data Centre and the American Geophysical Union (AGU) invite you to a half-day event on May 9th 2022 focusing on Open Science and Reproducibility.  \n\n\n\nTime: 12:00-17:00 Format: Zoom Webinar will be recorded. \n\n\n\nThis event will feature a number of speakers all addressing these themes on Open Science from various perspectives on a national and international level:  \n\n\n\nThe Path to Open\, Reproducible Science – Stories from the Research CommunityHow to Open Science – Practical Use Cases\, Lessons Learned from the Research CommunityOpen Science from a Broader Context – What Open Science Means from the National and International Perspectives\n\n\n\nSpeakerTitleTime in CESTJohan Rung- SciLifeLab-Data CentreIntroduction12:00Shelly Stall- American Geophysical UnionYour Journey Towards Open Science12:10-12:35Q&A12:35-12:40Sara El-Gebali- SciLifeLab-Data CentreThe road beyond open12:40-13:05Q&A13:05-13:10Break13:10-13:25Fredrik Ronquist- Swedish Museum of Natural History\, SciLifeLabFAIR and Open Science in the biodiversity research community13:25-13:50Q&A13:50-13:55David Diez del Molino- Swedish Museum of Natural HistoryGenome Erosion Pipeline13:55-14:20Q&A14:20-14:25Yuhan Douglas Rao- Cooperative Institute for Satellite and Earth System Studies / NC State University“If It Ain’t Broke\, Why Fix it?” – Open Science Lessons Learned in the Field14:25-14:50Q&A14:50-14:55Break14.55-15.10Daniel Bangert- Digital Repository of Ireland\, Royal Irish AcademyIreland’s national agenda for open research15:10-15:35Q&A15:35-15:40Christine Kirkpatrick- SDSC: San Diego SuperComputing CenterAn Open Science Future: National and International Perspectives15:40-16:05Q&A16:05-16:10Chelle Gentemann- NASAOpening up to Open Science16:10-16:35Q&A16:35-16:40Shelley StallClosing Remarks16:40-17:00\n\n\n\nRegister here
URL:https://www.scilifelab.se/event/agu-scilifelab/
LOCATION:Online event via Zoom
CATEGORIES:Event
ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2022/03/Artboard-1-1.png
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220509T151500
DTEND;TZID=Europe/Stockholm:20220509T160000
DTSTAMP:20260404T065701
CREATED:20220502T101150Z
LAST-MODIFIED:20220502T101852Z
UID:10000598-1652109300-1652112000@www.scilifelab.se
SUMMARY:The Svedberg seminar: Daniel Fürth
DESCRIPTION:Assistent Professor\, SciLifeLab Fellow at Uppsala University \n\n\n\nHybrid event: Trippelrummet\, Navet\, BMC and Online \n\n\n\n\n\n\n\n\n\nRegister here\n\n\n\nDr. Daniel Fürth completed his Ph.D. in neuroscience at Karolinska Institutet\, working on mesoscale connectomics using modified rabies virus tracing\, then postdoctoral work in RNA biology and method development at Cold Spring Harbor Laboratory\, Cancer Center\, New York. At Cold Spring Harbor he focused on enabling functional RNA genomics in situ at subcellular single-molecule resolution. Dr. Fürth’s expertise as a leader in both wet and dry lab neuroscience is internationally recognized with a Brain & Behavior Research Foundation NARSAD Young Investigator Award and computational funding from the Chan Zuckerberg Initiative. Dr. Fürth’s lab studies how information is stored\, processed and transmitted between cells. The focus is to find hitherto unknown mechanisms that can transfer symbolic information between cells. Identification of such transmission would enable us to read and write those messages.  \n\n\n\nTitle of the seminar: From in situ to in vivo sequencing\n\n\n\nUnbiased investigation of subcellular RNA localization and its control in vivo remains challenging. Current hybridization-based methods cannot differentiate small regulatory variants\, whilein situ sequencing is limited by short reads. We solved these problems using a bidirectional sequencing chemistry to efficiently image transcript-specific barcodes in situ\, which are then extracted and assembled into longer reads using NGS. Specific cis-regulatory elements usually found in mRNA 3′UTRs mediate RNA localization. Reverse transcription was primed towards the 3’UTR/polyA-tail junction in developing Drosophila and we discovered that in situ cDNA synthesis stalls just downstream of RNA-binding protein crosslink sites\, resulting in truncated cDNAs near RNA-binding protein motifs. We utilized these stop signatures to spatially map cis-regulatory motifs in specific alternative polyadenylation (APA) isoforms. A subset of genes displayed expression of two or more APA isoforms with distinct localization in situ\, to which we could identify their putative trans-acting partners. We validated our findings using both iCLIP-seq and targeted clampFISH probes. Our platform\, therefore\, provides a powerful way to discover novel RNA variants and protein interactions and their localization in situ. Lastly\, I’ll present recent developments of a fluorogenic and non-enzymatic sequencing chemistry capable of sequencing single molecules directly in live cells with subcellular precision.
URL:https://www.scilifelab.se/event/the-svedberg-seminar-daniel-furth/
LOCATION:Navet\, SciLifeLab Uppsala\, SciLifeLab Uppsala\, BMC C11\, Husargatan 3\, Uppsala\, 75237\, Sweden
CATEGORIES:Event
ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2022/04/Picture1-The-Svedberg-edited.png
ORGANIZER;CN="The Svedberg Seminar Series":MAILTO:thesvedberg@scilifelab.uu.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220510T084500
DTEND;TZID=Europe/Stockholm:20220510T170000
DTSTAMP:20260404T065701
CREATED:20220428T081405Z
LAST-MODIFIED:20220428T092504Z
UID:10000596-1652172300-1652202000@www.scilifelab.se
SUMMARY:Spatial and Single Cell Biology Platform Retreat
DESCRIPTION:Welcome to this meeting for the Spatial and Single Cell Biology Platform. Please note that this is an internal event for staff and members of the SSCB platform management group and invited members of the associated research groups of the SSCB Platform Scientific Directors. \n\n\n\nSign up here if you are an sSCB platform Employee\n\n\n\n\n\n\n\nProgram\n\n\n\n8:45 – 9.00 Coffee and registration \n\n\n\n9.00 – 9.20 Welcome and short introduction of platform (Charlotte/Mats) \n\n\n\nHU/PI presentation (≈10+10 min interactive presentations/discussion) \n\n\n\n9.20 – 9:40 PI/HU presentation 1 – In situ sequencing/Nilsson Lab \n\n\n\n9.40 – 10.00 PI presentation 2 – Spatial Proteomics/Lundberg Lab \n\n\n\n10.00- 10.20 PI presentation 3 – Spatial Transcriptomics/Lundeberg Lab \n\n\n\n10:20 – 10.40 PI presentation 4 – Advanced FISH Technologies/Bienko Lab \n\n\n\n10.40 – 11.40 Round tour of units \n\n\n\n11:40 – 12:30 Lunch and networking in Gamma 2 Lobby \n\n\n\n12.45 – 13.10 PI presentation 5 – Spatial Mass Spectrometry/ Andrén Lab \n\n\n\n13.10 – 13.30 PI presentation 6 – Eukaryotic sc genomics/Sandberg Lab \n\n\n\n13:40 – 15.00 Platform operation discussions/questions in groups of ≈ 5 in small meeting rooms ( \n\n\n\nFrom 13.30 Coffee and fika to bring to the small group discussions \n\n\n\nFocus on topics that involve everyone and not only the HU: \n\n\n\nHow to work closer together?Biggest challenges?Workflow from project start to delivery. How divide tasks within the team?User fee models? How to charge customer?How to prioritize projects?Queue?Unit Cross-over projects?\n\n\n\n15:00 – 16:30 Mingle with drinks and snacks and PI driven Panel discussion (whole group) – (Mats) \n\n\n\nLooking forward to see you all on May 10!
URL:https://www.scilifelab.se/event/sscb-platform-retreat/
LOCATION:Air&Fire\, SciLifeLab Stockholm\, Tomtebodavägen 23A\, Solna\, Sweden
CATEGORIES:Community
ORGANIZER;CN="SSCB Platform":MAILTO:charlotte.stadler@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220510T110000
DTEND;TZID=Europe/Stockholm:20220510T113000
DTSTAMP:20260404T065701
CREATED:20220505T144221Z
LAST-MODIFIED:20220505T145612Z
UID:10000602-1652180400-1652182200@www.scilifelab.se
SUMMARY:SciLifeLab Uppsala PhD&Postdoc seminar
DESCRIPTION:Welcome to SciLifeLab Uppsala PhD&Postdoc seminars! \n\n\n\nWe are very happy to host exciting talks by PhD students and Postdocs from a great variety of fields within SciLifeLab. \n\n\n\nSpeaker: Jinlin Li\, Researcher at the Heparan Sulfate Biology group (Jinlin Li’s lab)\, Dept. of Medical Biochemistry and MicrobiologyTitle: Heparanase attenuates ZIKV infection by impeding the stability of viral protein \n\n\n\nSummary: Heparanase (Hpa) is the only endoglycosidase enzyme in mammalian cells capable of cleaving heparan sulfate. In addition to the well-known functions in the regulation of glycosaminoglycans integrity\, accumulating evidence indicate Hpa plays vital roles in virus infection\, while the mechanisms are not yet fully understood\, especially in RNA virus infection. In this study\, we found Zika virus (ZIKV) reduced the expression of Hpa at the late life cycle of viral infection. Overexpression of wild-type Hpa but not the inactive enzymatic mutant (Hpa-DM) in Huh7 cells dramatically decreased the production of infectious virions. These findings were further confirmed by the results from Mouse Embryonic Fibroblasts (MEF) cells that knock-out of Hpa enhanced ZIKV production\, while overexpression of Hpa suppressed the production of virions. Further investigations indicated that overexpression of Hpa in Huh7 cells exhibited no obvious effects on ZIKV’s attachment/entry and replication steps\, but resulted in a significant downregulation of ZIKV envelope protein (E). Hpa was also shown to specifically degrade E protein when performed co-transfection of plasmids encoding Hpa and viral proteins in HEK-293T cells. Altogether\, our study discovered an unrecognized role of Hpa in virus infection and demonstrated that Hpa serves as a restriction factor for ZIKV infection.
URL:https://www.scilifelab.se/event/campus-uppsala-phd-postdoc-seminars/
LOCATION:Online event via Zoom
CATEGORIES:Community
ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2022/05/SciLifeLab-PhDPostdoc-conuncil-poster_landscape_May_10.png
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220510T120000
DTEND;TZID=Europe/Stockholm:20220510T130000
DTSTAMP:20260404T065701
CREATED:20220428T075520Z
LAST-MODIFIED:20220428T075524Z
UID:10000595-1652184000-1652187600@www.scilifelab.se
SUMMARY:National NMR Infrastructure at KBC. What can we do for you?
DESCRIPTION:In the frame of the “SciLifeLab Site Umeå / KBC Infrastructure Seminar Series”\, the seminars will be organised every second Tuesday during spring 2022 in turn with IceLab Lunch Pitches. The seminars will be held in a hybrid format IRL in Glasburen\, KBC\, and online via Zoom. Take the chance to get information on facilities\, possibilities and services that infrastructure\, both SciLifeLab-associated and local\, can offer! Learn more about the seminar series and Schedule for Spring 2022 here. \n\n\n\nOn May 10th\, 12:00-13:00\, SciLifeLab Site Umeå / KBC Infrastructure Seminar Series presents:  \n\n\n\n“National NMR Infrastructure at KBC. What can we do for you?” \n\n\n\nby Gerhard Gröbner\, Platform Director\, Professor\, Department of Chemistry\, Umeå University andJürgen Schleucher\, Platform Director\, Professor\, Department of Medical Biochemistry and Biophysics\, Umeå University \n\n\n\nSeminar description: The KBC based central NMR facility(Homepage) provides access to one of the most powerful liquid and solid-state NMR infrastructures in the Nordic countries and expertise for all researchers in the KBC and Campus environment. The facility serves large user groups spanning a remarkably wide range of fields\, such as materials science\, chemical biology\, organic synthesis\, structural biology\, plant- and environmental sciences\, biogeochemistry and medical metabolomics. Local researchers profit strongly from the facility’s status as a national infrastructure and different structural biology facilities and expertise (“Integrated Structure Biology”) at UMU. Fragment-based screening is also offered as national support in collaboration with CBCS/LCBU\, including comprehensive substance libraries. The facility is also closely linked to large research initiatives at the campus such as MIMS\, UCMP\, Bio4Energy\, UPSC\, the Swedish Metabolomics Center (SMC) and with SLU through collaborations and by offering service. \n\n\n\nActivities: If required\, a short guided tour to the NMR facility and drop-in discussions with NMR people about potential projects could be organised after the seminar. \n\n\n\nRegistration: \n\n\n\nSign up (latest by May 9th\, 10 a.m.) for on-site attendance to reserve your free lunch sandwich: \n\n\n\nor follow online via Zoom (registration is not required): https://umu.zoom.us/j/63138997026 . \n\n\n\nOrganisers: SciLifeLab Site Umeå and Chemical Biological Centre (KBC)
URL:https://www.scilifelab.se/event/national-nmr-infrastructure-at-kbc-what-can-we-do-for-you/
LOCATION:Glasburen Seminar Room\, Chemical Biological Centre (KBC) Building\, Umeå University\, Umeå\, 901 87\, Sweden
CATEGORIES:Event
ORGANIZER;CN="SciLifeLab Ume%C3%A5":MAILTO:umea@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220510T120000
DTEND;TZID=Europe/Stockholm:20220513T160000
DTSTAMP:20260404T065701
CREATED:20220224T125406Z
LAST-MODIFIED:20220302T073938Z
UID:10000536-1652184000-1652457600@www.scilifelab.se
SUMMARY:Nordic ELIXIR-GOBLET Train-the-Trainer - Online
DESCRIPTION:This course offers guidance\, ideas and tips for designing training/teaching\, development and delivery on training activities\, all based on research-driven educational principles. This course will cover 4 main topics: \n\n\n\nLearning principles and how they apply to training and teachingDesign and plan session\, course\, materialsTeaching techniques to enhance learner engagement and participationAssessment and feedback in training and teaching\n\n\n\n\n\n\n\nNote! The course is highly interactive and hence it is important that you\, as a participant\, actively contribute to all sessions and elements of the course \n\n\n\nThis course will be delivered through Canvas learning management system.  \n\n\n\nCourse Time: 12:00 – 16:00 CETCourse Format: Online via Zoom and it will include breakout sessions \n\n\n\n\n\n\n\nContact\n\n\n\nFor queries\, please don’t hesitate to contact us at education@nbis.se \n\n\n\n\n\n\n\n\nCOURSE WEBSITE AND PROGRAM\n\n\n\nREGISTRATION\n\n\n\n\n\n\n\n\nDeadline for applying to the course is 3rd of April. You will receive notification regarding acceptance to the course or if you are on the reserve list no later than one week after the closing of the registration. \n\n\n\n\n\n\n\nCourse fee\n\n\n\nThere is no course attendance fee. \n\n\n\nNote! If you are accepted and decide not to attend without communicating the reason for the no-show with us\, we will invoice a no-show-fee of 200 Euros. \n\n\n\nThe invoicing information needs to be included in the registration in order to guarantee your spot in the training event\, if you are to be accepted. By giving the invoice information you hereby confirm that the group leader/PI/manager has given a consent regarding your possible participation in the Training event. NOTE – Uppsala University cannot invoice individuals. \n\n\n\n\n\n\n\nCourse content\n\n\n\nLearning Objectives: \n\n\n\nTo get acquainted with Learning principles and how they apply to trainingTo be able to select and use training techniques that can help enhance learner engagement and participationTo learn how to use assessment and feedback in trainingTo learn about session\, course\, and materials design\n\n\n\nLearning Outcome: \n\n\n\nBy the end of this course\, learners will be able to: \n\n\n\nName learning principles that a good teacher/instructor should have in mindDescribe at least three training techniques\, drawing on learning principlesDesign a training session and a courseDevelop assessment questionnairesEnumerate types of materials needed for each part of a training session or course\n\n\n\n\n\n\n\nTarget audience\n\n\n\nWhoever is interested in becoming a trainer/instructor\, or improving your training skills. If you have questions like the following ones\, this course may be very helpful to you. \n\n\n\nHow learning works?How do I use learning principles and theories to improve my teaching/training?How do I make my teaching/training more engaging and effective?How should I adjust my teaching/training to different types of learners?How do I ensure learning progress?How can I assess whether my students are actually understanding my lessons? Are they actually learning?What is the best balance between theory and practice?How can I best assess whether learning is occurring and/or has occurred?What works in a classroom and what doesn’t?\n\n\n\n\n\n\n\nSelection criteria\n\n\n\nWe will accept a maximum of 20 participants. Priority will be given to applicants from institutes and organisations across the Nordic research community and to participants from Nordic ELIXIR nodes. \n\n\n\n\n\n\n\nCourse team\n\n\n\nInstructors: \n\n\n\nJessica Lindvall (ELIXIR-SE Training Coordinator\, NBIS\, Sweden \n\n\n\nNina Norgren (ELIXIR-SE\, Training Coordinator\, NBIS\, Sweden) \n\n\n\nNazeefa Fatima (ELIXIR-NO\, Data Steward\, UiO\, Norway) \n\n\n\nErik Hjerde (ELIXIR-NO\, Training Coordinator\, UiT\, Norway) \n\n\n\nPriit Adler (ELIXIR-EE\, Trainer\, UT\, Estonia) \n\n\n\nAllegra Via (ELIXIR-IT\, Training Coordinator\, IBPM-CNR\, IT) \n\n\n\nPatricia Palagi (ELIXIR-CH\, Training coordinator\, SIB) \n\n\n\nOrganisers: \n\n\n\nELIXIR-SE \n\n\n\nELIXIR-NO \n\n\n\nELIXIR-FI \n\n\n\nELIXIR-EE
URL:https://www.scilifelab.se/event/nordic-elixir-goblet-train-the-trainer-online/
LOCATION:Online event via Zoom
CATEGORIES:Course
ORGANIZER;CN="NBIS - National Bioinformatics Infrastructure Sweden":MAILTO:education@nbis.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220511T110000
DTEND;TZID=Europe/Stockholm:20220511T160000
DTSTAMP:20260404T065701
CREATED:20220425T081942Z
LAST-MODIFIED:20220427T142909Z
UID:10000593-1652266800-1652284800@www.scilifelab.se
SUMMARY:Spatial Biology Tour
DESCRIPTION:The Spatial proteomics unit together with Lunaphore invite you to a workshop to learn about their new instrument and service with the COMET platform. The Spatial proteomics unit is the first lab in Sweden to offer multiplexed protein detection with the COMET platform\, which relies on sequential indirect immunofluorescence using off the shelf primary antibodies. The workshop also allows for a guideed tour of the lab and an instrument demonstration. Lunch will be served for registered participants.  \n\n\n\nplease sign up here to attend
URL:https://www.scilifelab.se/event/spatial-biology-tour/
LOCATION:Air&Fire\, SciLifeLab Stockholm\, Tomtebodavägen 23A\, Solna\, Sweden
CATEGORIES:Event
ORGANIZER;CN="Spatial Proteomics Unit":MAILTO:spatial.proteomics@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220511T140000
DTEND;TZID=Europe/Stockholm:20220511T153000
DTSTAMP:20260404T065701
CREATED:20220426T132422Z
LAST-MODIFIED:20220507T113616Z
UID:10000594-1652277600-1652283000@www.scilifelab.se
SUMMARY:Decoding the development of the human spinal cord by multi-omics
DESCRIPTION:Decoding the development of the human spinal cord by multi-omics \n\n\n\nXiaofei Li and Erik Sundström \n\n\n\nHDCA Seminar Series 2022 | Spinal cord \n\n\n\nThe human spinal cord has highly diverse cell types\, which are generated during development\, governed by a series of temporal and spatial events for proper spinal cord assembly and function. However\, the molecular regulation of cell fate specification in the human developing spinal cord remains largely unknown. Here\, by performing single-cell RNA sequencing\, spatial transcriptomics and in situ sequencing\, we integrate the datasets and provide a comprehensive single-cell and spatial transcriptomic atlas of the developing human spinal cord of the first trimester\, from postconceptional week 5 to 12. We observe that all major cell populations in human adult spinal cord have been specified within the first trimester with abundant cell states\, and identify the key genes associated with cell fate choices and their spatial expression. Unexpectedly\, we find that during early cell fate specification\, many human neural progenitor cells have lost their self-renewal capacity. Further the the expression of gliogensis genes is much higher in human compared to the correspondent rodents at the early stage\, suggesting earlier gliogenesis in human. Finally\, we demonstrate how to use our developmental map for molecular cues that direct sequential cellular differentiation and define cells and locations associated to both normal development and spinal cord diseases. \n\n\n\nsign up to attend\n\n\n\nPlease register also if you want to participate in the digital broadcast. The Zoom link will be sent out through the registration system.  \n\n\n\n– \n\n\n\nHuman developmental cell atlas (HDCA) is the Swedish effort within the human cell atlas (HCA)\, one of the largest international scientific projects. The project aim is to create a comprehensive molecular atlas of human prenatal development at the molecular resolution using state-of-the-art multi-omic technologies such as single-cell RNA-seq\, Spatial Transcriptomics\, in situ sequencing in order to provide deeper insight into how variations and deviations contribute to health and disease. \n\n\n\nThe HDCA Seminar Series 2022 invites you to join us on a journey of early human organogenesis of several organs at the single-cell and spatial resolution. Seminars will be held at SciLifeLab Gamma building on Wednesdays at 14:00 or 15:00 and also via Zoom. After each seminar\, we will have up to 30 min round up discussions with the speaker on how you can contribute to the atlas! \n\n\n\nWarm Welcome!
URL:https://www.scilifelab.se/event/decoding-the-development-of-the-human-spinal-cord-by-multi-omics/
LOCATION:Gamma 2 Lunchroom\, SciLifeLab\, Tomtebodavägen 23\, Solna\, Sweden
CATEGORIES:Event
ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2022/04/hdca_logo.png
ORGANIZER;CN="The Human Developmental Cell Atlas":MAILTO:hdca-sweden@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220511T141500
DTEND;TZID=Europe/Stockholm:20220511T154500
DTSTAMP:20260404T065701
CREATED:20220502T110248Z
LAST-MODIFIED:20220504T075959Z
UID:10000599-1652278500-1652283900@www.scilifelab.se
SUMMARY:SciLifeLab COVID-19 seminar: Lilly Schwieler and Elham Rostami
DESCRIPTION:Topic: Neurological implication of COVID \n\n\n\nThe third SciLifeLab COVID-19 seminar this spring starts with Lilly Schwieler\, Associate Professor\, Physiology and Pharmacology\, Karolinska Institutet\,talking about Peripheral and central levels of kynurenine metabolites in COVID-19 patients. Elham Rostami\, Associate Professor\, Neurosurgery\, Uppsala university\,then continues the seminar with her talk on COVID19 and neurological complication. \n\n\n\nSchedule\n\n\n\n14:15-15:00Peripheral and central levels of kynurenine metabolites in COVID-19 patients.Lilly Schwieler\, Associate Professor\, Physiology and Pharmacology\, Karolinska Institutet15:00-15:45COVID19 and neurological complicationElham Rostami\, Associate Professor\, Neurosurgery\, Uppsala University\n\n\n\n\n\n\n\nRegistration is mandatory to get the Zoom link for the event  \n\n\n\n\nREGISTRATION\n\n\n\nBIOS & ABSTRACTS
URL:https://www.scilifelab.se/event/scilifelab-covid-19-seminar-lilly-schwieler-and-elham-rostami/
LOCATION:Online event via Zoom
CATEGORIES:Event
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220516T080000
DTEND;TZID=Europe/Stockholm:20220517T170000
DTSTAMP:20260404T065701
CREATED:20220309T093342Z
LAST-MODIFIED:20220512T143421Z
UID:10000548-1652688000-1652806800@www.scilifelab.se
SUMMARY:Planetary Biology Workshop
DESCRIPTION:EMBL-SciLifeLab workshop on the theme Planetary Biology \n\n\n\nThe purpose of the workshop is to enhance connectivity between researchers at both\, SciLifeLab and EMBL\, to identify new collaboration ideas\, and to promote joint technology and infrastructure resource development within Planetary Biology. \n\n\n\nThis is one of many workshops that will follow the conclusion of the MoU between SciLifeLab and EMBL in 2021. \n\n\n\nThe workshop is a hybrid event. Physical location is the EMBL Heidelberg campus\, where in-person attendance is limited. Allocation of spaces is on a first-come first-served basis.  \n\n\n\nPlease note: there are two separate registration links for on-site or virtual participation. In case you sign up for on-site participation but your availability changes\, please make sure to inform the responsible contacts. \n\n\n\nThe workshop will include talks on a broad set of themes including: \n\n\n\nBiodiversity Genomics & Reference Genome SequencingEcology & EvolutionBiogeochemistry & EcosystemsData-driven Planetary Biology\,\n\n\n\nAs well as invited keynote speakers and panel discussions. \n\n\n\nread more and sign up here\n\n\n\nDay 1\, Monday 16th May\, 2022 \n\n\n\n13:00Welcome and opening remarksEdith HeardDirector General of EMBLOlli KallioniemiDirector of SciLifeLab13:10Introduction and overview of Planetary BiologyDetlev ArendtPlanetary Biology Co-Chair\, Senior Scientist\, Group Leader\, EMBLOlga Vinnere Pettersson & Stefan BertilssonCo-Leads Planetary Biology Capability\, SciLifeLab13:30Session 1: Biodiversity Genomics & Reference Genome Sequencing (15 mins + 5 mins Q&A per speaker in each session)ModeratorPeter Harrison\, Genome Analysis Team Leader\, EMBL-EBISpeakersFergal Martin\, Vertebrate Annotation Coordinator\, EMBL-EBIKerstin Lindblad Toh (remote)\, Professor in Comparative Genomics\, Uppsala University\, Scientific Director of Vertebrate Genome Biology\, Broad InstituteDetlev Arendt\, Planetary Biology Co-Chair\, Senior Scientist\, Group Leader\, EMBLOve Nilsson\, Group Leader Control of Flowering Time and Tree Phenology\, Umeå Plant Science Center14:50 Coffee break15:10Session 2: Ecology and EvolutionModeratorOlga Vinnere Pettersson\, Co-Lead Planetary Biology Capability\, SciLifeLabSpeakersLove Dalén\, Professor of Evolutionary Genetics\, Swedish Museum of Natural History\, Research Leader at Center for Palaeogenetics\, StockholmMichael Dorrity\, Group Leader Structural and Computational Biology\, EMBLJames Sharpe (remote) \, Head of EMBL Barcelona\, Group Leader in Tissue Biology and Disease ModellingAnna Rosling\, Group Leader Ecology and Evolution in Soil Fungi\, Uppsala University16:30Keynote by Mark BlaxterWellcome Sanger Institute17:15Summary and Q&A\n\n\n\nDay 2\, Tuesday 17th May\, 2022 \n\n\n\n09:00Arrival and Coffee09:30Keynote by Martin PolzUniversity of Vienna10:20Session 3: Biogeochemistry & Ecosystems(15 mins + 5 mins Q&A per speaker in each session)ModeratorStefan Bertilsson\, Co-Lead Planetary Biology Capability\, SciLifeLabSpeakersMichael Zimmermann\, Group Leader in Structural and Computational Biology\, EMBLFlora Vincent\, Incoming Group Leader in Developmental Biology; Post Doctoral Fellow at Weizmann Institute of Science\, RehovotSara Hallin\, Professor at the Department of Forest Mycology and Plant Pathology\, Swedish University of Agricultural SciencesMark Dopson\, Professor at the Department of Biology and Environmental Science\, Linnaeus University11:40 Break12:40Session 4: Data-driven Planetary BiologyModeratorOliver Stegle\, Associate Group Leader in Genome Biology\, EMBLSpeakersTomas Roslin (remote)\, Professor at the Department of Ecology\, Swedish University of Agricultural SciencesPeer Bork\, Director of EMBL Heidelberg\, Group Leader in Structural and Computational Biology\, EMBLAnders Andersson\, Group Leader in Environmental Genomics\, Royal Institute of TechnologyAnna Kreshuk\, Group Leader in Cell Biology and Biophysics14:00Summary and Q&A14:15Coffee break14:45Panel Discussion 1: Technological Infrastructure Needs for PB ResearchModeratorStefan Bertilsson\, Co-Lead Planetary Biology Capability\, SciLifeLabPanelistsYannick Schwab\, Team Leader Volume Correlative Light and Electron Microscopy and Head of Electron Microscopy Core Facility\, EMBLTimo Zimmermann\, Team Leader Advanced Light Microscopy Technology Development and Service Provision\, EMBLLinda Sandblad\, Scientific Platform Director Cellular and Molecular Imaging\, Umeå University\, SciLifeLabOlga Vinnere Pettersson\, Project coordinator at Department of Immunology\, Genetics and Pathology\, Uppsala University; Co-Lead Planetary Biology Capability\, SciLifeLabAnnika Johansson\, Head of Swedish Metabolomics Centre\, Umeå University\, SciLifeLab16:00Short break16:10Panel Discussion 2: Data Collection in PB ResearchModeratorOlga Vinnere Pettersson\, Co-Lead Planetary Biology Capability\, SciLifeLabPanelistsRainer Pepperkok\, Director of Scientific Core Facilities and Scientific Services\, Team Leader Membrane traffic and Organelle Biogenesis\, EMBLStefan Bertilsson\, Professor in Functional Ecology of Freshwaters\, Swedish University of Agricultural Sciences; Director of the Swedish Infrastructure for Ecosystem Science (SITES); Co-Lead Planetary Biology Capability\, SciLifeLabFredrik Ronqvist\, Professor in the Department of Bioinformatics and Genetics\, Swedish Museum of Natural History; Swedish Biodiversity Data Infrastructure (SBDI)16:40Panel Discussion 3: Data Management and Processing in PB ResearchModeratorFergal Martin\, Eukaryotic Annotation Team Leader\, EMBL-EBIPanelistsGuy Cochrane (remote)\, Team Leader Data Coordination and Archiving\, EMBL-EBIBlokeshwaran Manoharan\, Expert in Metagenomics; National Bioinformatics Infrastructure Sweden (NBIS)Johan Rung\, Head of Data Center\, SciLifeLab17:00Conclusion and Closing Remarks\n\n\n\n \n\n\n\n \n\n\n\n \n\n\n\n \n\n\n\n \n\n\n\nScientific committee SciLifeLab\n\n\n\nStefan Bertilsson\, SLUOlga Vinnere Pettersson\, Uppsala University
URL:https://www.scilifelab.se/event/planetary-biology-workshop/
LOCATION:EMBL Heidelberg\, Meyerhofstraße 1\, Heidelberg\, Germany
CATEGORIES:Event
ATTACH;FMTTYPE=image/jpeg:https://www.scilifelab.se/wp-content/uploads/2021/12/AdobeStock_421805105_Planetary_biology_WP.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220516T091500
DTEND;TZID=Europe/Stockholm:20220516T163000
DTSTAMP:20260404T065701
CREATED:20220321T154432Z
LAST-MODIFIED:20220323T125900Z
UID:10000564-1652692500-1652718600@www.scilifelab.se
SUMMARY:AI / Data-driven life science
DESCRIPTION:Life science research is becoming increasingly dependent on data\, and never before has so much data been generated today. The amount and complexity increase exponentially\, and when this data becomes open to researchers around the world\, more scientific discoveries are made possible. The rapid technological development in life sciences\, combined with innovations in computing and AI\, will play an increasingly important role in research and development and affect virtually all areas of medicine and science. \n\n\n\nDuring this day\, you will meet prominent international and local researchers\, take part in current research\, and discuss open data\, AI\, ethics\, and visualization related to life science.  \n\n\n\nContacts: Carolina Wählby and Bent Persson. \n\n\n\nVenue: Ångströmslaboratoriet\, Lägerhyddsvägen 1\, Uppsala \n\n\n\nRegistration opens at the end of March.  \n\n\n\nProgram and registration will be published here! \n\n\n\n\n\n\n\nThe event is part of Uppsala University’s multidisciplinary theme week in technology and science from May 16 to 20\, at the Ångström Laboratory. During the week\, you will be able to take part in current research in AI / Data-driven life science\, the universe and mathematical physics\, materials\, energy\, and climate change.
URL:https://www.scilifelab.se/event/ai-data-driven-life-science/
LOCATION:Ångströmlaboratoriet\, Lägerhyddsvägen 1\, Uppsala\, Sweden
CATEGORIES:Event
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220516T171500
DTEND;TZID=Europe/Stockholm:20220516T181500
DTSTAMP:20260404T065701
CREATED:20220422T112304Z
LAST-MODIFIED:20220505T130333Z
UID:10000591-1652721300-1652724900@www.scilifelab.se
SUMMARY:The Svedberg seminar: Simon Elsässer
DESCRIPTION:Register and get the link here\n\n\n\n\n\nSimon Elsässer is  Associate Professor at Karolinska Institutet\, Department of Medical Biochemistry and Biophysics. He has studied at University of Tübingen and Harvard University\, and received his Ph.D. from The Rockefeller University in 2012. He has performed postdoctoral research at MRC Laboratory of Molecular Biology and was recruited to Karolinska Institutet as a SciLifeLab Fellow in 2015. His research combines synthetic biology methods to probe and manipulate proteins in the living cell with quantitative ‘omics readouts\, focusing on stem cells\, gene expression regulation and epigenomics. \n\n\n\nTitle of the seminar: Exploring the dynamics of the pluripotent epigenome and lineage choice in development\n\n\n\n \n\n\n\nShort Abstract: \n\n\n\nThe first lineage choice made in human embryo development separates trophectoderm from the inner cell mass\, which proceeds to form the pluripotent epiblast and primitive endoderm. We discovered that Polycomb repressive complex 2 (PRC2) maintains naïve pluripotency and restricts an intrinsic capacity of pre-implantation pluripotent stem cells to give rise to extraembryonic lineages. Through quantitative ChIP-seq and single-cell transcriptomics\, we demonstrate that PRC2-mediated repression provides a highly adaptive mechanism to restrict lineage potential during early human development.Webpage: http://www.elsaesserlab.org
URL:https://www.scilifelab.se/event/simon-elsasser/
LOCATION:Online event via Zoom
CATEGORIES:Event
ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2022/04/Picture1-The-Svedberg-edited.png
ORGANIZER;CN="The Svedberg Seminar Series":MAILTO:thesvedberg@scilifelab.uu.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220518T090000
DTEND;TZID=Europe/Stockholm:20220519T130000
DTSTAMP:20260404T065701
CREATED:20220408T121642Z
LAST-MODIFIED:20220408T130957Z
UID:10000578-1652864400-1652965200@www.scilifelab.se
SUMMARY:Handling Pandemic Omics Data in the Nordics
DESCRIPTION:Dates: 18 & 19th May (9:00-13:00)\n\n\n\nLocation: online via Zoom\n\n\n\nThe current COVID-19 pandemic has understandably received considerable attention worldwide over the last few years. As it spread across the globe\, the pandemic posed significant challenges for society\, governmental bodies\, healthcare systems\, and research communities. Unprecedented efforts were necessary to  generate\, handle\, and report the sheer amount of complex data required to be able to understand how SARS-CoV-2 was spreading\, and develop efficient policies to fight the pandemic. \n\n\n\nSciLifeLab Data Centre\, ELIXIR Norway and ELIXIR Estonia have organised an online event exploring how Nordic countries handled omics data related to the SARS-CoV-2 pandemic. We invite bioinformaticians\, data stewards\, research scientists\, and anyone else interested in this topic to attend. We will focus in particular on how sequencing efforts were coordinated\, how data was managed and shared\, and how data was used and communicated to different groups. We will also discuss the importance of the FAIR principles in pandemic data management\, and which tools and pipelines facilitated efforts. We hope that this will shed light on best practices that could be adopted across the Nordics for future pandemics\, and how we might best prepare for them. We also hope to identify key resources that have wider applicability and can be reused further. \n\n\n\nThe programme is available at:  \n\n\n\nhttps://nordic-compbio.iscbsc.org/omics-data. \n\n\n\nFor any queries about the meeting\, please email nazeefaf@uio.no \n\n\n\n \n\n\n\nRegister Here
URL:https://www.scilifelab.se/event/handling-pandemic-omics-data-in-the-nordics/
LOCATION:Online event via Zoom
CATEGORIES:Event
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220519T120000
DTEND;TZID=Europe/Stockholm:20220519T130000
DTSTAMP:20260404T065701
CREATED:20220513T080446Z
LAST-MODIFIED:20220513T080631Z
UID:10000606-1652961600-1652965200@www.scilifelab.se
SUMMARY:Campus Solna Seminar
DESCRIPTION:Seminars are back in person! \n\n\n\nThe speakers for Thursday 19 May: \n\n\n\n1) Erik Wernersson (Magda Bienko’s group\, alpha4):“deconwolf: free and open source deconvolution for widefield microscopy.” \n\n\n\n2) Carlos Gallardo Dodd (Claudia Kutter’s group\, gamma5):“Cell type-specific deployment of codons and anticodons in mammals.” \n\n\n\nTime: 12:00-13:00 \n\n\n\nPlace: Air&Fire\, SciLifeLab Campus Solna
URL:https://www.scilifelab.se/event/campus-solna-seminar/
LOCATION:Air&Fire\, SciLifeLab Stockholm\, Tomtebodavägen 23A\, Solna\, Sweden
CATEGORIES:Community
ORGANIZER;CN="SciLifeLab Solna PhD & Postdoc Council":MAILTO:phd-council@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220519T140000
DTEND;TZID=Europe/Stockholm:20220519T180000
DTSTAMP:20260404T065701
CREATED:20220330T154729Z
LAST-MODIFIED:20220330T154904Z
UID:10000576-1652968800-1652983200@www.scilifelab.se
SUMMARY:Towards characterizing the human 3D-proteome - Nobel Symposium
DESCRIPTION:Public keynote lectures: 14:00-18:00 \n\n\n\nNo registration necessary\, but when the room is full\, it is full \n\n\n\nRead more\n\n\n\n\n\n\n\nProgram\n\n\n\n14:00 Introduction – Arne Elofsson14:15 Demis Hassabis\, DeepMind\, Using AI to model biology14:45 Sarah Teichmann\, Wellcome Sanger Institute\, TBD15:15 Sergey Ovchinnikov\, Harvard\, Inverting protein structure prediction models to solve problems in biology.For this talk I’ll describe some exciting applications of protein structure prediction models such as TrRosetta\, RoseTTAFold and AlphaFold. More specifically\, I’ll describe how we can invert these models for protein design\, generation of multiple sequence alignments and navigating the conformational landscape to predict structure(s) from single sequence\n\n\n\n15:45-16:15 Coffee \n\n\n\n16:15 Debora Marks\, Harvard\, TBD16:45 Alice Y Ting\, Stanford\, Spatial proteomics and transcriptomics via enzyme-catalyzed proximity labelingWhere a protein is localized in the cell exerts tremendous influence over its function\, interaction partners\, dynamics\, and modifications. Enzyme-catalyzed proximity labeling (PL) has emerged as a powerful and generalizable method to map the locations and interactions of endogenous proteins in the context of living cells\, applicable to even membraneless organelles and transient interactions that are inaccessible to traditional methods such as affinity purification. I will give a brief account of PL method development\, including directed evolution of the PL enzymes APEX and TurboID\, and then describe new efforts to extend PL to RNA and proteome trafficking.\n\n\n\n17:15 John Jumper\, DeepMind\, TBD17:45 Final Comments\n\n\n\nThe Nobel Foundation’s symposium activities were initiated in 1965. Over the years\, they have achieved a high international standing. The symposia are devoted to science areas where breakthroughs are occurring. \n\n\n\nThis symposium aims to bring together experts from various fields with the explicit goal of outlining a joint worldwide strategy to obtain a structural map of the human proteome. In addition to determining the structure and composition of all human proteins and their interactions\, it would also require understanding the flexible and dynamic supra-molecular structures in living cells\, such as multi-component membraneless organelles. A few key findings from the last years make us believe that this goal is achievable. First\, detailed knowledge of composition (splice forms\, PTMs) and expression levels in different cells are becoming available. Secondly\, Cryo-EM has revolutionized the structural determination of large protein complexes. Finally\, using co-evolution and advances in deep learning\, it is now possible to predict the structure of many individual proteins and complexes directly using no other information than the sequences and their evolutionary history. In the next few years\, combining the progress in these three areas will provide an opportunity to provide unprecedented molecular insights into the function of cells. Theoretical methods combined with ever-increasing sequence information will enable an understanding sequence and structural variation within populations\, both in humans and in disease-causing organisms.
URL:https://www.scilifelab.se/event/towards-characterizing-the-human-3d-proteome/
LOCATION:Beijersalen\, Kungl. Vetenskapakademien\, Lilla Frescativägen 4A\, Stockholm\, Sweden
CATEGORIES:Event
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220523T151500
DTEND;TZID=Europe/Stockholm:20220523T161500
DTSTAMP:20260404T065701
CREATED:20220422T114620Z
LAST-MODIFIED:20220523T063854Z
UID:10000592-1653318900-1653322500@www.scilifelab.se
SUMMARY:The Svedberg seminar: Tanja Slotte
DESCRIPTION:Tanja Slotte\, Assoc. Prof.Stockholm University\, Sweden \n\n\n\nRegister and get the Link\n\n\n\nAssoc. Prof. Tanja Slotte is a population geneticist who is interested in the genetic causes and genomic consequences of plant mating system shifts and the evolution of mating system supergenes. She received her PhD from Uppsala University in 2007\, followed by a postdoc at University of Toronto. She started her own group at Uppsala University in 2010 and moved to Stockholm University to take up a SciLifeLab Fellow position in 2014. She is currently Associate Professor in Ecological Genomics at Stockholm University. \n\n\n\nTitle of the seminar: Sequencing the supergene that governs Darwin’s different forms of flower\n\n\n\nSupergenes are responsible for a wide variety of balanced polymorphisms in nature\, yet our understanding of their origins and evolution remains incomplete. The reciprocal placement of stigmas and anthers in pin and thrum floral morphs of distylous species constitutes an iconic example of a balanced polymorphism governed by a supergene. Recent studies have shown that the Primula distyly S-locus supergene is hemizygous due to structural variation at the supergene. If this genetic architecture is common to other distyly supergenes\, it could have major implications for the evolution and loss of distyly. To shed further light on this question we have characterized the genetic architecture and evolution of the distyly supergene in Linum\, one of the plant systems where Dawin first described distyly. We have generated multiple high-quality genome assemblies of Linum species as a genomic framework for evolutionary studies. Here\, we leverage this framework to identify the distyly S-locus supergene and study its evolution and expression. Our results show that hemizygosity and thrum-specific expression are major features of the Linum distyly supergene\, and suggest that the supergene has arisen in a stepwise manner. Our findings demonstrate remarkable convergence in the genetic architecture\, origin and evolution of the distyly supergene among systems with independently derived distyly\, and shed light on the evolution of the classic supergene that governs Darwin’s “different forms of flowers”.
URL:https://www.scilifelab.se/event/the-svedberg-seminar-tanja-slotte/
LOCATION:Online event via Zoom
CATEGORIES:Event
ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2022/04/Picture1-The-Svedberg-edited.png
ORGANIZER;CN="The Svedberg Seminar Series":MAILTO:thesvedberg@scilifelab.uu.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220524T100000
DTEND;TZID=Europe/Stockholm:20220524T110000
DTSTAMP:20260404T065701
CREATED:20220504T155131Z
LAST-MODIFIED:20220504T155220Z
UID:10000601-1653386400-1653390000@www.scilifelab.se
SUMMARY:Solid tumours as dynamic cellular ecosystems
DESCRIPTION:Dr. Alex Swarbrick\, Garvan Institute for Medical Research\, Australia \n\n\n\nLocation: Air/FireDate: 10.00 24th of May \n\n\n\nAbstract: A well-established principle in developmental biology is that cellular context governs cell fate\, differentiation\, proliferation and survival. There is emerging evidence that solid tumours are also complex cellular systems\, or ecosystems\, in which interactions between neoplastic\, stromal and immune cells govern the natural history of disease and response to treatment. In this seminar Dr Swarbrick will discuss his latest research applying cellular genomics to understanding breast cancer ecosystems\, with the aim of making new discoveries relevant to disease stratification and treatment.
URL:https://www.scilifelab.se/event/solid-tumours-as-dynamic-cellular-ecosystems/
LOCATION:Air&Fire\, SciLifeLab Stockholm\, Tomtebodavägen 23A\, Solna\, Sweden
CATEGORIES:Event
ORGANIZER;CN="Joakim Lundeberg":MAILTO:joakim.lundeberg@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220524T110000
DTEND;TZID=Europe/Stockholm:20220524T115000
DTSTAMP:20260404T065701
CREATED:20220520T144620Z
LAST-MODIFIED:20220520T145411Z
UID:10000613-1653390000-1653393000@www.scilifelab.se
SUMMARY:SciLifeLab Uppsala PhD&Postdoc seminar
DESCRIPTION:Welcome to SciLifeLab Uppsala PhD&Postdoc seminars! \nWe are very happy to host exciting talks by PhD students and Postdocs from a great variety of fields within SciLifeLab. \n\n \n\n\n\nSpeaker 1: Hongxing Zhao\, Researcher at Ulf Landegren Lab (Molecular Tools)\, Dept. of Immunology\, Genetics and Pathology\n\n\n\nTitle: Detection of SARS-CoV-2 antibodies from dried blood spots of vaccine individuals by proximity extension assay Summary: We have developed a solution-phase assay for sensitive detection of SARS-CoV-2 antibodies in serum or dried blood spots (DBS) from infected or vaccinated individuals. Detection probes were prepared by conjugating the recombinant S1-RBD or nucleocapsid (NC) to either of a pair of oligonucleotides. Upon incubation with COVID-19 patient serum or DBS from vaccinated individuals\, the multivalency of the antibodies brings pairs of oligonucleotides that have been conjugated to the viral proteins in proximity. The oligonucleotides can then undergo enzymatic DNA extension via a proximity extension assay (PEA)\, and the resulting amplicons are sensitively detected by real-time PCR or end-point read out using ELISA mechine. This antibody PEA (AbPEA) test uses only 1 µl neat or diluted serum or one ø1.2 mm disc cut from a DBS. All 100 investigated sera and 21 DBS collected prior to the COVID-19 outbreak were negative\, demonstrating a 100% specificity. The sensitivity of the assay for infected patient after 10 days symptom reached 99.8% [95% confidence interval: 0.9935-1]. Anti-S1 antibodies could be detected directly in punched-out discs from self-sampled DBS 11 days after vaccination\, and it reached a maximum at 3 weeks after a first inoculation. Examination of a serially collected DBS from 14 individuals all showed similar trends of antibody responses after both a first and second vaccination\, although antibody levels varied between individuals. \n\n\n\nSpeaker 2: Manon Dubol\, PhD. Postdoctoral Researcher at Erika Comasco Neuropsychopharmacology Group\, Dept. of Women and Children’s Health\n\n\n\n\n\n\n\nTitle: Grey matter morphometry and MRI data-driven classification of premenstrual dysphoric disorder (PMDD) Summary: Premenstrual dysphoric disorder (PMDD) is recognized in the DSM-5 as a hormone-related depressive disorder\, specific to women’s mental health 1. Women who suffer from PMDD experience affective\, cognitive\, and physical symptoms that peak during the late luteal phase of the menstrual cycle\, and remit shortly in the beginning of the next cycle 2. The key affective symptoms of PMDD point to anatomical and functional brain impairment\, suggesting an impaired top-down inhibitory process involving limbic brain structures 3. However\, very little is known about brain morphological alterations in PMDD. The present study aimed at investigating the grey matter structures that distinguish women with PMDD from healthy controls\, by use of multiscale structural MRI analyses. Differences in grey matter structure between the groups were investigated by use of Voxel- and Surface Based Morphometry. Furthermore\, machine learning and multivariate pattern analysis was performed using a leave-one-fold-out cross-validation procedure\, to test whether MRI measures (volume\, thickness\, gyrification\, sulcal depth and cortical complexity) could distinguish women with PMDD from healthy controls. The findings point to PMDD-specific grey matter structure in regions of corticolimbic networks\, in line with the hypothesis of an impaired top-down inhibitory circuit involving limbic structures in PMDD. Furthermore\, the results include widespread cortical regions and cerebellar areas\, suggesting the involvement of distinct networks in PMDD pathophysiology. These effects prominently involved volumetric and cortical thickness measures\, as further highlighted by multivariate pattern classification analyses. Such differences in brain structure may help explaining the variations in brain function previously reported in women with PMDD during the symptomatic phase.
URL:https://www.scilifelab.se/event/scilifelab-uppsala-phdpostdoc-seminar/
LOCATION:Online event via Zoom
CATEGORIES:Event
ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2022/05/SciLifeLab-PhDPostdoc-conuncil-poster_landscape_May_24.png
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220524T120000
DTEND;TZID=Europe/Stockholm:20220524T130000
DTSTAMP:20260404T065701
CREATED:20220519T081250Z
LAST-MODIFIED:20220519T081441Z
UID:10000611-1653393600-1653397200@www.scilifelab.se
SUMMARY:NGS at NGI
DESCRIPTION:In the frame of the “SciLifeLab Site Umeå / KBC Infrastructure Seminar Series”\, the seminars will be organised every second Tuesday during spring 2022 in turn with IceLab Lunch Pitches. The seminars will be held in a hybrid format IRL in Glasburen\, KBC\, and online via Zoom. Take the chance to get information on facilities\, possibilities and services that infrastructure\, both SciLifeLab-associated and local\, can offer! Learn more about the seminar series and Schedule for Spring 2022 here. \n\n\n\nOn May 24th\, 12:00-13:00\, you are welcome to participate in the seminar \n\n\n\nNGS at NGI \n\n\n\nby Kristina Benevides\, Project coordinator\, National Genomics Infrastructure (NGI)\, SciLifeLab\, and research engineer in bioinformatics and sequencing\, UPSC Bioinformatics Facility\, Department of Plant Physiology\, Umeå University \n\n\n\nSeminar description\n\n\n\nGot samples? We’ve got the sequencing! NGI(https://ngisweden.scilifelab.se/) is one of the largest platforms at SciLifeLab and provides both established and cutting-edge genomics technologies to diverse user groups across Sweden and internationally. There’s a wide range of applications as NGI is equipped with both short- and long read technologies\, as well as SNP genotyping- and DNA methylation arrays. The platform assists users in project design\, data generation\, analysis and management of data in order to support genomics research in all subject areas. \n\n\n\nPrepare for your next (generation) sequencing experiment as we’ll get into the nitty-gritty of some different methods\, sample types and requirements. \n\n\n\nThere will be a fun online science quiz at the end – participate to win some swag! \n\n\n\nRegistration\n\n\n\nSign up (latest by May 23rd\, 10 a.m.) for on-site attendance to reserve your free lunch sandwich: \n\n\n\nsign up\n\n\n\nor follow online via Zoom: https://umu.zoom.us/j/63138997026 (registration is not required). \n\n\n\nOrganisers\n\n\n\nSciLifeLab Site Umeå and Chemical Biological Centre (KBC)
URL:https://www.scilifelab.se/event/ngs-at-ngi/
LOCATION:Glasburen Seminar Room\, Chemical Biological Centre (KBC) Building\, Umeå University\, Umeå\, 901 87\, Sweden
CATEGORIES:Event
ORGANIZER;CN="SciLifeLab Ume%C3%A5":MAILTO:umea@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220525T130000
DTEND;TZID=Europe/Stockholm:20220525T140000
DTSTAMP:20260404T065701
CREATED:20220507T134201Z
LAST-MODIFIED:20220510T114934Z
UID:10000603-1653483600-1653487200@www.scilifelab.se
SUMMARY:A novel\, antibody-based radiopharmaceutical for advanced thyroid cancer
DESCRIPTION:Presenter: Dr Marika Nestor\, Department of Immunology\, genetics and pathology\, Uppsala University\, Sweden \n\n\n\nMolecular radiotherapy is increasingly becoming a powerhouse in the field of cancer- and radiation therapy. By targeting a structure that is abundant on tumor cells but scarce in healthy tissues\, a cancer-targeting molecule labeled with a therapeutic radionuclide can mediate the delivery of radioactivity specifically to cancer cells. This creates a targeted\, localized form of radiotherapy that combines the advantages of systemic therapy with therapeutically effective radiation. \n\n\n\nIn a collaboration with the Drug Discovery & Development platform at Science for Life Laboratory\, we have developed an antibody-based radiopharmaceutical for molecular radiotherapy of advanced thyroid carcinoma. The project spans over the whole early development chain; from preclinical innovation in the lab\, dosimetry and proof-of-concept in animal models\, to upscaled production and preparations for first-in-man studies. \n\n\n\nDr Nestor in her presentation will discuss the process from innovation to implementation of the project\, both from a research and a commercialization perspective. \n\n\n\nsign up here\n\n\n\nMarika Nestor leads a translational research group at the Department of Immunology\, Genetics and Pathology\, Uppsala University. Her research group focuses on radionuclide targeting and radiosensitization of cancer cells. She obtained her PhD at Uppsala University in 2006\, and became an Associate Professor in 2012. In 2013 she was awarded the Göran Gustafsson prize for young scientists\, in 2016 the Junior Investigator Award from the Swedish Cancer Society\, and in 2020 the Senior Investigator Award. In 2019\, she was awarded a grant from Sweden’s innovation agency VINNOVA to facilitate clinical translation of her findings\, as well as an Attractive Innovation Award by UU Innovation.
URL:https://www.scilifelab.se/event/a-novel-antibody-based-radiopharmaceutical-for-advanced-thyroid-cancer/
LOCATION:Online event via Zoom
CATEGORIES:Event
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220530T080000
DTEND;TZID=Europe/Stockholm:20220610T170000
DTSTAMP:20260404T065701
CREATED:20220203T142206Z
LAST-MODIFIED:20220210T134248Z
UID:10000520-1653897600-1654880400@www.scilifelab.se
SUMMARY:New Imaging and Fluctuation Methods: Super-Resolution\, Light-Sheet\, STED-FCS and FRET-FCS
DESCRIPTION:Web-based PhD-level course\, 3 hp credits\, by the ALM facility at Scilifelab. \n\n\n\nFlyer_220119\n\n\n\nLight-Sheet Imaging\n\n\n\nLong time-lapse imaging of live modelorganisms with low phototoxicityCombined light-sheet andsuper-resolution\n\n\n\nSuper-Resolution Imaging in Living Cells – MoNaLISA\n\n\n\nSmart probes50 nm resolution at 1-2 Hz100 x 100 um field of view time lapse imaging\n\n\n\n \n\n\n\nSTED-FCS\n\n\n\nFluctuation spectroscopy with 30 nm resolutionSub-diffraction dynamics in living cells\n\n\n\n \n\n\n\nFRET-FCS\n\n\n\nEasy detection of protein-protein interactions in living cellsHighly sensitive detection of rare oligomers in living cells\n\n\n\nLecturers\n\n\n\nAndreas BodénErdinc SezginIlaria TestaStefan Wennmalm\, stewen@kth.se \n\n\n\nRegistration\n\n\n\nPlease register by sending an e-mail with your contact details to: stewen@kth.se.Registration deadline: May 20\, 2022
URL:https://www.scilifelab.se/event/new-imaging-and-fluctuation-methods-super-resolution-light-sheet-sted-fcs-and-fret-fcs/
LOCATION:Online event via Zoom
CATEGORIES:Course
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220530T160000
DTEND;TZID=Europe/Stockholm:20220530T170000
DTSTAMP:20260404T065701
CREATED:20220421T091500Z
LAST-MODIFIED:20220421T112618Z
UID:10000588-1653926400-1653930000@www.scilifelab.se
SUMMARY:FAIRPoints-Enhancing Sample Provenance and Experimental Reproducibility
DESCRIPTION:Location: Online via Zoom \n\n\n\n\n\nSee Event in your Time Zone \n\n\n\nSpeaker: Rory Macneil  \n\n\n\nLack of reliable information about sample usage\, location\, provenance\, metadata and experimental use is a core barrier to experimental reproducibility and general FAIRification of data. This presentation will describe how these issues are being addressed in the design and development of a sample management module within the RSpace electronic lab notebook\, focusing on three specific challenges: (1) Incorporating sample data into experimental documentation; (2) Associating PIDS like IGSNs and RRIDS into sample metadata; and (3) Export of sample metadata in required formats to different domain repositories and databases.  \n\n\n\nFAIRPoints is an event series highlighting pragmatic measures developed by the community towards the implementation of the FAIR (Findable\, Accessible\, Interoperable\, Reusable) data principles\, in collaboration with GoFAIR US\, SDSC\, AGU\, and SciLifeLab Data Centre. \n\n\n\nSpeaker bio: \n\n\n\nRory Macneil is CEO of Research Space\, which provides RSpace\, an electronic lab notebook and research data management platform\, and host of the FAIR Data Podcast.  In these roles\, and through participation in organizations and forums like the Research Data Alliance\, numerous conferences and events\, and conversations with researchers\, research data managers\, policy makers\, funders\, and tools developers\, he enjoys exploring practical ways in which FAIRification of data can be advanced. \n\n\n\n\n\n\n\nRegister here\n\n\n\nSign up for future events here \n\n\n\nTwitter: @FAIR_Points
URL:https://www.scilifelab.se/event/fairpoints-sample-provenance/
LOCATION:Online event via Zoom
CATEGORIES:Event
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