BEGIN:VCALENDAR VERSION:2.0 PRODID:-//SciLifeLab - ECPv6.15.20//NONSGML v1.0//EN CALSCALE:GREGORIAN METHOD:PUBLISH X-WR-CALNAME:SciLifeLab X-ORIGINAL-URL:https://www.scilifelab.se X-WR-CALDESC:Events for SciLifeLab REFRESH-INTERVAL;VALUE=DURATION:PT1H X-Robots-Tag:noindex X-PUBLISHED-TTL:PT1H BEGIN:VTIMEZONE TZID:Europe/Stockholm BEGIN:DAYLIGHT TZOFFSETFROM:+0100 TZOFFSETTO:+0200 TZNAME:CEST DTSTART:20230326T010000 END:DAYLIGHT BEGIN:STANDARD TZOFFSETFROM:+0200 TZOFFSETTO:+0100 TZNAME:CET DTSTART:20231029T010000 END:STANDARD BEGIN:DAYLIGHT TZOFFSETFROM:+0100 TZOFFSETTO:+0200 TZNAME:CEST DTSTART:20240331T010000 END:DAYLIGHT BEGIN:STANDARD TZOFFSETFROM:+0200 TZOFFSETTO:+0100 TZNAME:CET DTSTART:20241027T010000 END:STANDARD BEGIN:DAYLIGHT TZOFFSETFROM:+0100 TZOFFSETTO:+0200 TZNAME:CEST DTSTART:20250330T010000 END:DAYLIGHT BEGIN:STANDARD TZOFFSETFROM:+0200 TZOFFSETTO:+0100 TZNAME:CET DTSTART:20251026T010000 END:STANDARD BEGIN:DAYLIGHT TZOFFSETFROM:+0100 TZOFFSETTO:+0200 TZNAME:CEST DTSTART:20260329T010000 END:DAYLIGHT BEGIN:STANDARD TZOFFSETFROM:+0200 TZOFFSETTO:+0100 TZNAME:CET DTSTART:20261025T010000 END:STANDARD END:VTIMEZONE BEGIN:VEVENT DTSTART;TZID=Europe/Stockholm:20240226T151500 DTEND;TZID=Europe/Stockholm:20240226T161500 DTSTAMP:20260502T080510 CREATED:20240207T162516Z LAST-MODIFIED:20240207T162519Z UID:10001149-1708960500-1708964100@www.scilifelab.se SUMMARY:[The Svedberg seminar] - Spatial biodiversity modeling with remote sensing and AI DESCRIPTION:Tobias Andermann \n\n\n\nAssistant Professor\, DDLS fellowUppsala University \n\n\n\n \n\n\n\n\n\n\n\nBio\n\n\n\nTobias Andermann is a biodiversity researcher dedicated to providing data and computatio- nal tools for combating the global biodiversity crisis. His group\, the Biodiversity Data Lab\, is working on the intersection of molecular biology\, spatial ecology\, and machine learning\, with the mission to provide a more comprehensive view on the distribution of biodiversity\, including hidden diversity of inconspicuous and even undescribed species through the use of environmental DNA. \n\n\n\n \n\n\n\nSpatial biodiversity modeling with remote sensing and AI\n\n\n\nThere is an ever-increasing need for developing standardized ways of quantifying the biodiversity value of a site. This need arises from international and local policies (e.g. the COP15 UN Biodiversity agreement) as well as from the independent investments of companies world-wide in developing biodiversity-positive profiles\, motivated by their public perception. This momentum provides an unprecedented opportunity to efficiently protect biodiversity on a large scale to turn around the alarmingly negative biodiversity trends of the recent decades and centuries. While individual biodiversity assessments for specific sites can be done through targeted inventories\, either through taxonomic experts or increasingly through the use of environmental DNA\, we also need ways of scaling up such biodiversity evaluations to larger scales\, covering entire regions or countries. AI models provide a unique tool to leverage complex biodiversity and remote sensing data to make predictions of biodiversity on large spatial scales\, while at the same time providing high spatial resolution. In this talk I will present some of these models from my ongoing research and discuss their utility\, as well as their current shortcomings and limitations. \n\n\n\n \n\n\n\n\n\n\n\nHost: Joëlle Rüegg joelle.ruegg@ebc.uu.se\, UU URL:https://www.scilifelab.se/event/the-svedberg-seminar-tobias-andermann/ LOCATION:BMC Room C8:301\, Husargatan 3\, Uppsala\, Sweden CATEGORIES:Event ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2022/02/Picture1-The-Svedberg.png ORGANIZER;CN="The Svedberg Seminar Series":MAILTO:thesvedberg@scilifelab.uu.se END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Stockholm:20240312T080000 DTEND;TZID=Europe/Stockholm:20240315T170000 DTSTAMP:20260502T080510 CREATED:20231215T124733Z LAST-MODIFIED:20240304T133407Z UID:10001071-1710230400-1710522000@www.scilifelab.se SUMMARY:Nordic Oikos 2024 - New perspectives in ecological and evolutionary research DESCRIPTION:The Planetary Biology Capability is organizing a session on “Exploring and understanding biodiversity” that will count on the participation of Prof. Davis Wardle (Umeå University)\, Prof. Katherine McMahon (University of Wisconsin-Madison) and Prof. Mark Blaxter (Sanger Institute). The DDLS research area\, Evolution\, and Biodiversity\, is organizing a session on the importance of data-driven life science in ecology and evolution. The DDLS Fellow Kelly Swarts is one of the Plenary speakers. \n\n\n\nSciLifeLab related sessions:\n\n\n\n\nPlanetary Biology pre-conference session: Towards the efficient use of molecular approaches and infrastructure to accelerate research in the field of Planetary Biology\n\n\n\n\nThis session aims to enhance connections between SciLifeLab\, the Planetary Biology Capability\, and the PB research community in Lund. Discussions will address challenges and opportunities for the efficient use of SciLifeLab’s services to support and accelerate research in the field of Planetary Biology.  \n\n\n\n12th March from 15:00 to 17:00. Venue: Room Heden G110\, Ecology Building\, Sölvegatan 37\, Lund. \n\n\n\nProgram for the session \n\n\n\n15:00-15:20:     Introduction to the PB concept and capability leads. \n\n\n\n15:20-15:40:    Overview of PB research in Lund. Bengt Hansson\, Lund University \n\n\n\n15:40 – 15:50:   Presentation of SciLifeLab Lund and facilities. \n\n\n\n15:50 – 16:00:   Break \n\n\n\n16:00 – 17:00:   Presentation of SciLifeLab Platforms and PB-related projects. Discussion on needs and challenges for using SciLifeLab services. \n\n\n\nRegister\n\n\n\n\nPlanetary biology: exploring and understanding biodiversity (S1)\n\n\n\n\nBiodiversity at local to global scales is a key feature that constrains and controls ecosystem function and key biogeochemical processes. In this session\, we welcome contributions addressing various aspects of biodiversity\, including how to assess it\, key drivers affecting biodiversity\, and the consequences of change (and loss) of biodiversity. We particularly encourage presentations that emphasize large-scale patterns and processes that move beyond the local scale. \n\n\n\n\nDDLS: the importance of data-driven life science in ecology and evolution (S13)\n\n\n\n\nThe importance of data-driven science in Ecology and Evolution” will spotlight innovative research methodologies and findings utilizing computational techniques and massive data streams to explore ecological dynamics. This session could encompass presentations on leveraging high-throughput sequencing\, remote sensing\, machine learning\, and AI to investigate biodiversity patterns\, ecosystem functioning\, species interactions\, and the impact of environmental changes on ecosystems\, fostering discussions on cutting-edge approaches shaping the future of ecological and evolution research within the Nordic scientific community and beyond. \n\n\n\n\n\n\n\nWe are delighted to invite you to the upcoming biennial meeting of the Nordic Society Oikos​ 12-15th of March 2024 with the theme New perspectives in ecological and evolutionary research. The meeting will be jointly organised by the Nordic Society Oikos and the European Ecological Federation​ (EEF). The conference will be held at AF Borgen​ in the picturesque area Lundagård​ in Lund\, southern Sweden. \n\n\n\nThe meeting provides a platform for researchers engaged in all aspects of ecology and evolutionary biology. We have a broad set of session themes covering a diverse range of topics in basic and applied research\, and we warmly welcome submissions for both oral- and poster presentations exploring these themes. Data Driven Life Science​\, Planetary Biology​\, Biodiversity and Ecosystem services in a Changing Climate​ (BECC) will be organizing theme sessions ensuring the representation of a diverse set of perspectives. Registration and abstract submission will open October 17th. Registration will close February 1\, 2024 at 00:00 \n\n\n\nRegister\n\n\n\nAt the Nordic Society 2024 meeting\, you can anticipate: \n\n\n\n\nEngaging plenary speakers and thematic sessions\, delivering insightful perspectives\n\n\n\nTwo dedicated poster sessions\n\n\n\nVibrant discussions and ample opportunities for social interaction throughout the meeting\n\n\n\nSocial events\, conference dinner and excursion to foster inspiration and facilitate networking with fellow participants\n\n\n\n\nWe hope you join us in Lund to exchange knowledge\, forge new connections\, and explore new frontiers in ecological and evolutionary biology. \n\n\n\nWe are looking forward to welcome you in Lund! \n\n\n\nLocal organizing committee:\n\n\n\nLund University \n\n\n\nAnna Runemark – Biodiversity \n\n\n\nCaroline Isaksson – Evolutionary Ecology \n\n\n\nSusana Garcia Dominguez – Evolutionary Ecology \n\n\n\nRichard Walters – Centre for Environmental and Climate Science \n\n\n\nPetronella Wessman – Biodiversity \n\n\n\nMargot Knapen – Physical Geography and Ecosystem Science \n\n\n\nSwedish University of Agricultural Sciences\, Alnarp \n\n\n\nÅsa Lankinen – Integrated Plant Protection \n\n\n\nKristina Karlsson Green – Chemical Ecology Agriculture \n\n\n\nNordic Society Oikos \n\n\n\nJohan Nilsson  \n\n\n\nÅsa Langefors \n\n\n\nMichael Tobler URL:https://www.scilifelab.se/event/nordic-oikos-2024-new-perspectives-in-ecological-and-evolutionary-research/ LOCATION:AF Borgen\, Sandgatan 2\, Lund\, Sweden CATEGORIES:Event END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Stockholm:20240408T130000 DTEND;TZID=Europe/Stockholm:20240409T153000 DTSTAMP:20260502T080510 CREATED:20240402T125022Z LAST-MODIFIED:20240402T153433Z UID:10001224-1712581200-1712676600@www.scilifelab.se SUMMARY:Data Driven Life Science Seminars: "Data driven research in evolution and biodiversity" DESCRIPTION:Data Driven Life Science Seminars. On the topic of “Data driven research in evolution and biodiversity “. \n\n\n\nWelcome to attend the open\, digital seminars as part of the recruitment process given by the top candidates for the group leader position in data driven life science (DDLS). \n\n\n\nLink to join the webinar\, password: 526883 \n\n\n\nRead more on the event website \n\n\n\nApril 8th\n\n\n\n13.00-14.00: Malin Olofsson\, Swedish University of Agricultural Sciences\, SLU. Combining multiple data to enhance understanding of phytoplankton evolution and biodiversity \n\n\n\n14.30-15.30: Mariana Pires Braga\, Swedish University of Agricultural Sciences\, SLU. Biotic interactions: teasing apart evolutionary processes from data biases \n\n\n\nApril 9th\n\n\n\n13.00-14.00: Harith Farooq\, University of Copenhagen\, Denmark. Biodiversity Data to guide Macroecology and Conservation \n\n\n\n14.30-15.30: Pooja Choksi\, University of Minnesota\, USA. tbd URL:https://www.scilifelab.se/event/data-driven-life-science-seminars-data-driven-research-in-evolution-and-biodiversity/ LOCATION:Loftets bankettsal\, Ultuna\, Duhrevägen 8\, Uppsala CATEGORIES:Event END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Stockholm:20240418T100000 DTEND;TZID=Europe/Stockholm:20240418T110000 DTSTAMP:20260502T080510 CREATED:20240328T075011Z LAST-MODIFIED:20240404T101946Z UID:10001214-1713434400-1713438000@www.scilifelab.se SUMMARY:Leveraging supercomputers for data-driven life science research: examples from Berzelius DESCRIPTION:This event is part of the Tools for AI/ML research in life sciences event series arranged by the SciLifeLab Data Centre. This webinar is organized in collaboration with the National Supercomputer Centre\, LiU as well as the EuroHPC National Competence Centre Sweden (ENCCS). \n\n\n\nTitle: Leveraging supercomputers for data-driven life science research: examples of use cases and introduction to Berzelius \n\n\n\nSpeaker: Soumi Chaki and Xuan Gu (National Supercomputer Centre\, Linköping University)\, Kimmo Kartasalo (Karolinska Institute)\, Claudio Mirabello (Linköping University). \n\n\n\nWhere and when: April 18\, 2024 at 10:00-11:00 Stockholm time\, online. Registration is open till April 18 at 9:00. \n\n\n\nAbstract: \n\n\n\nAgenda:10:00-10:05 – Introduction to supercomputers and Berzelius10:05-10:20 – Developing computational pathology AI models for improved prostate cancer diagnostics and prognostics using Berzelius (Kimmo Kartasalo\, Post-doctoral researcher\, Karolinska Institute)10:20-10:35 – Modelling large protein complexes on Berzelius (Claudio Mirabello\, Principal Research Engineer\, Docent\, Linköping University)10:35-10:50 – Resource allocation procedure and user support available on Berzelius10:50-11:00 – Q&A session \n\n\n\nPowerful GPU supercomputers allow to carry out large-scale experiments in a fraction of time that it would otherwise take as well as pursue research projects that would otherwise not be possible. Life science researchers at Swedish universities can apply and make use of the Berzelius AI/ML cluster at the National Supercomputer Center in Linköping. In this one hour long webinar two researchers will present how they use Berzelius in their work and what research it allows them to carry out. In addition\, we will present the technical specifications of Berzelius\, the resource allocation procedure\, as well as the available user support. We will give a short demonstration on how to request GPU resources on Berzelius and run scripts/software on the allocated GPU(s). This webinar is particularly tailored for researchers interested in and working with AI/ML methods. \n\n\n\nRegister to join the event\n\n\n\nMore about the event series: \n\n\n\nTools for AI/ML research in life sciences is an event series by the SciLifeLab Data Centre aimed at life science researchers who use machine learning methods in their work. The goal of the events in this series is to provide introductions to different tools for ML research but also to foster discussions around our practices and how they can be improved. The events takes place virtually (over Zoom) and are open to researchers in Sweden and beyond. Each event is scheduled for 60 minutes\, consisting of a talk and an extended discussion. Follow the page of the event series to learn about future seminars. \n\n\n\nFor questions about the events please contact the organizing team by emailing serve@scilifelab.se \n\n\n\n \n\n\n\nScientific lead: Prof. Ola Spjuth\, SciLifeLab Data Centre and Uppsala University and DDLS \n\n\n\nContact information: serve@scilifelab.se URL:https://www.scilifelab.se/event/leveraging-supercomputers/ LOCATION:Online event via Zoom CATEGORIES:Event END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Stockholm:20240419T100000 DTEND;TZID=Europe/Stockholm:20240419T110000 DTSTAMP:20260502T080510 CREATED:20240115T121853Z LAST-MODIFIED:20240115T121929Z UID:10001109-1713520800-1713524400@www.scilifelab.se SUMMARY:Model-guided ML approaches to integrative omics analyses DESCRIPTION:NBIS\, Scilifelab’s Bioinformatics platform\, arranges an open AI and IO Seminar Series aimed at knowledge-sharing about Artificial Intelligence and Integrative Omics (AI & IO) analysis and applications in the Life Science community. The seminar series is open to everyone. The seminar is run over Zoom on the third Friday of the month during academic terms\, typically between 10 and 11 am\, with ca. 45 min long presentation and 15 min discussion. \n\n\n\nFor further info\, please see this website. \n\n\n\n \n\n\n\n\n\n\n\nModel-guided ML approaches to integrative omics analyses\n\n\n\nCemal Erdem\, DDLS fellow\, Umeå University \n\n\n\nClick here to join zoom conference URL:https://www.scilifelab.se/event/model-guided-ml-approaches-to-integrative-omics-analyses/ LOCATION:Online event via Zoom CATEGORIES:Event END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Stockholm:20240425T113000 DTEND;TZID=Europe/Stockholm:20240426T170000 DTSTAMP:20260502T080510 CREATED:20231221T105648Z LAST-MODIFIED:20240425T193524Z UID:10001075-1714044600-1714150800@www.scilifelab.se SUMMARY:Cell and Molecular Biology - DDLS symposium DESCRIPTION:Welcome to the Cell and Molecular Biology Symposium\, starting with lunch at Restaurant Lyktan from 11:30. The conference then takes place in the Birgit Thilander Lecture Hall in Academicum. The program includes presentations from local and national experts within data driven life science research – and a keynote lecture by Prof. Edda Klipp from the Humboldt University in Berlin. \n\n\n\nDay two\, on April 26\, takes place in the AstraZeneca facilities in Mölndal. Here we will meet with the exciting BioVenture Hub and learn about how AstraZeneca works with data driven life science in a clinical setting. Bus transfer from Clarion Hotel Post leaves at 07:30 directly to Astra Zeneca. \n\n\n\n\nPractical information\n\n\n\n\n\nPublic Transport to Medicinareberget \n\n\n\nThursday\, April 27 \n\n\n\nPlease note that due to construction work\, there are disturbances in the tram operations at nearby stops Medicinaregatan and Sahlgrenska Huvudentrén. \n\n\n\nFind your best route through the Västtrafik website or app. \n\n\n\n\n\nCoach to Astra Zeneca \n\n\n\nFriday\, April 26 \n\n\n\nA chartered bus will depart from Clarion Post Hotel at 07:30\, directly to the Astra Zeneca Conference Center (PGN Entrance).  \n\n\n\n\n\nGuidelines for Self-Transport Arrivals to Astra Zeneca \n\n\n\nFriday\, April 26 \n\n\n\nWhether you’re arriving by public transport\, bike\, or car\, kindly make your way to the KC-entrance at Pepparedsleden 1. \n\n\n\nPlease be punctual at 08:00\, as you’ll be guided from the entrance to the conference area. \n\n\n\n\n\n\nProgram\n\n\n\nClick to expand and see the program \n\n\n\nThursday\, April 25\nApril 2510:30Expert Group meeting11:30LunchRestaurant Lyktan13:00Welcome WordsMargit Mahlapuu\, University of GothenburgSverker Holmgren\, ChalmersOla Engkvist\, AstraZeneca13:10Precision Glycomics: How AI and advanced mass spectrometry are changing the gameDaniel Bojar\, University of Gothenburg13:40Towards a universal molecular framework for structure prediction and designPatrick Bryant\, SciLifeLab/Stockholm University (DDLS Fellow)Protein-ligand docking is an established tool in drug discovery and development to narrow down potential therapeutics for experimental testing. However\, a high-quality protein structure is required and often the protein is treated as fully or partially rigid. Here we develop an AI system that can predict the fully flexible all-atom structure of protein-ligand complexes directly\, given a multiple sequence alignment representation of the protein\, protein pocket information\, and a SMILES string representing the ligand.14:10Integrating single-cell transcriptomics with cellular phenotypesJoan Camuñas\, University of Gothenburg14:40Thermodynamics-informed modeling of biochemical reaction and regulation networksEdda Klipp\, Humboldt-Universität zu Berlin15:20Coffee Break15:50Tumor biology using multiomicsAnders Ståhlberg\, University of Gothenburg16:10Multiomics – state of art data generation and analysis at NGIMattias Ormestad and Franziska Bonath\, National Genomics InfrastructureMultiomics projects can span over long time frames\, sometimes years\, until all data is created. Often sequencing is an integral part and is outsourced to a core facility like NGI. For projects in which data generation is performed by different groups\, it is crucial that important information about library preparation\, sequencing and analysis is recorded and available to all other participants. Therefore\, NGI applies quality control measures and reports important metadata to ensure that our users can use our data with confidence even years after data generation.16:30Data-Driven Microscopy: the automation of end-to-end imaging workflowsElisabet Carlsohn and Rafael Camacho\, SciLifeLab/University of GothenburgBiological complexity mandates comprehensive imaging for statistically significant results. Manual operation impedes large dataset acquisition\, affecting reproducibility. Smart microscopy\, integrating image analysis and computer-controlled microscopes\, streamlines workflows. At GU’s Centre for Cellular Imaging\, we offer open-access “smart microscopy” services optimizing data management with next-gen file formats\, ome-zarr\, community-driven visualization tools\, napari\, and collaborative platforms\, webknossos. This ensures efficient resource utilization in the era of data-driven life sciences.17:00Tour to SciLifeLab units in Gothenburg Optional\, sign up in registration form18:00Dinner for CMB fellows and experts\, and speakers\n\n\n\n \n\n\n\n\nFriday\, April 26\nApril 2607:30Bus transport to Astra Zeneca Conference Centre in Mölndal08:00Visitor registration Astra Zeneca Conference Centre in Mölndal08:25IntroductionOla Engkvist\, AstraZeneca & Margit Mahlapuu\, University of Gothenburg08:30Empowering data-driven innovations in Life Sciences: A journey with GU VenturesKlementina Österberg\, GU Ventures & Carl-Peter Mattsson\, GU VenturesKlementina Österberg CEO & Carl-Peter Mattsson Investment director at GU Ventures will present their experiences and the journeys to create successful new business in collaborations with investors\, industry and the eco system. They will also show some examples of these journeys with their companies.09:15BioVentureHub – an antidote to the incubent’s curseMagnus Björsne\, AstraZeneca BioVentureHub10:00Coffee Break10:30Precision Medicine from the start – using omic data to deliver actionable insight to drug discovery and developmentDaniel Muthas\, AstraZeneca11:15Data driven life sciences in a clinical settingJesper Havsol\, AstraZeneca12:00Networking lunch12:40Tour – “The Amazing Journey the story about Astra Zeneca in Mölndal”Optional\, sign up in registration form\n\n\n\n \n\n\n\n\nSymposium Program for Download and PrintDownload\n\n\n\nData-driven Life Science\n\n\n\nThe future of life science is data-driven\, providing major new opportunities to explore and understand biology\, human health and changing ecosystems. The SciLifeLab & Wallenberg National Program for Data-Driven Life Science (DDLS) is set up to make use of these opportunities. URL:https://www.scilifelab.se/event/ddls-symposium-cell-and-molecular-biology/ LOCATION:Birgit Thilander Lecture Hall\, Medicinaregatan 3\, Göteborg CATEGORIES:Event END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Stockholm:20240516T141500 DTEND;TZID=Europe/Stockholm:20240516T163500 DTSTAMP:20260502T080510 CREATED:20240429T090516Z LAST-MODIFIED:20240429T091240Z UID:10001246-1715868900-1715877300@www.scilifelab.se SUMMARY:Uppsala University DDLS Fellows - public seminars with candidates DESCRIPTION:Welcome to a data driven-rich afternoon of scientific presentations by 4 candidates for the DDLS program fellow position on Data-driven Precision Medicine and Diagnostics and Biträdande Universitets Lektor position at Uppsala University. \n\n\n\nMeeting details\n\n\n\nMonday\, May 6\, 2024 14:15-16:35 \n\n\n\nZoom link >>   \n\n\n\nMötes-ID: 640 7985 9903 \n\n\n\nSchedule\n\n\n\n14:15-14:50     \n\n\n\nSergi Sayols Baixeras\, Uppsala University\, Dep. of Medical Sciences\, Sweden \n\n\n\nNovel Insights fromZMetagenomics and Metabolomics on Atherosclerotic Disease \n\n\n\n14:50-15:25      \n\n\n\nQiaoli Wang\, Harvard University Medical School\, Cambridge\, USA \n\n\n\nAnticipatory Detection of Upper-Gastrointestinal Cancers: Staying One Step Ahead with a Dash of Wit \n\n\n\n15:25-16:00      \n\n\n\nMuhammad Arif\, National Institute on Alcohol Abuse and Alcoholism\, Rockville\, USA \n\n\n\nIntegrative Multi-Omics Frameworks for Understanding the Molecular Mechanism of Progressive Diseases \n\n\n\n16:00-16:35      \n\n\n\nFilipe Barata\, Centre for Digital Health Interventions\, ETH Zurich\, Switzerland & Stanford University\, Palo Alto\, USA.  \n\n\n\nAdvancing Personalized Healthcare Through Digital Biomarkers URL:https://www.scilifelab.se/event/uppsala-university-ddls-fellows-public-seminars-with-candidates/ CATEGORIES:Event ORGANIZER;CN="SciLifeLab Event":MAILTO:events@scilifelab.se END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Stockholm:20240517T100000 DTEND;TZID=Europe/Stockholm:20240517T110000 DTSTAMP:20260502T080510 CREATED:20240311T123125Z LAST-MODIFIED:20240311T123126Z UID:10001199-1715940000-1715943600@www.scilifelab.se SUMMARY:Digital twins and integrative systems biology DESCRIPTION:NBIS\, Scilifelab’s Bioinformatics platform\, arranges an open AI and IO Seminar Series aimed at knowledge-sharing about Artificial Intelligence and Integrative Omics (AI & IO) analysis and applications in the Life Science community. The seminar series is open to everyone. The seminar is run over Zoom on the third Friday of the month during academic terms\, typically between 10 and 11 am\, with ca. 45 min long presentation and 15 min discussion. \n\n\n\nFor further info\, please see this website. \n\n\n\n \n\n\n\n\n\n\n\nDigital twins and integrative systems biology\n\n\n\nGunnar Cedersund\, Linköping University \n\n\n\nClick here to join zoom conference URL:https://www.scilifelab.se/event/digital-twins-and-integrative-systems-biology/ LOCATION:Online event via Zoom CATEGORIES:Event END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Stockholm:20240521T103000 DTEND;TZID=Europe/Stockholm:20240521T120000 DTSTAMP:20260502T080510 CREATED:20240515T074909Z LAST-MODIFIED:20240515T074909Z UID:10001259-1716287400-1716292800@www.scilifelab.se SUMMARY:Uppsala University DDLS Fellows - public seminars with candidates - part II DESCRIPTION:Welcome to the second data driven-rich morning of scientific presentations by 2 candidates for the DDLS program fellow position on Data-driven Precision Medicine and Diagnostics and Biträdande Universitets Lektor position at Uppsala University. \n\n\n\nSchedule \n\n\n\nMeeting details\n\n\n\nTuesday\, May 21\, 2024 10:30-12:00 \n\n\n\nZoom link >>   \n\n\n\nMötes-ID: 663 2681 5420 \n\n\n\nSchedule\n\n\n\n10:30-11:05     \n\n\n\nMarcel Tarbier\, Karolinska Institutet\, Stockholm\, Sweden \n\n\n\nInto the Single-Verse: Inferring complex gene and cell features from gene expression – and an excursion through space and time \n\n\n\n11:05-11:40      \n\n\n\nMuhammad Arif\, National Institute on Alcohol Abuse and Alcoholism\, Rockville\, USA \n\n\n\nIntegrative Multi-Omics Frameworks for Understanding the Molecular Mechanism of Progressive Diseases URL:https://www.scilifelab.se/event/uppsala-university-ddls-fellows-public-seminars-with-candidates-part-ii/ CATEGORIES:Event ORGANIZER;CN="SciLifeLab Event":MAILTO:events@scilifelab.se END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Stockholm:20240619T090000 DTEND;TZID=Europe/Stockholm:20240619T120000 DTSTAMP:20260502T080510 CREATED:20240614T151702Z LAST-MODIFIED:20240614T151815Z UID:10001276-1718787600-1718798400@www.scilifelab.se SUMMARY:Uppsala University DDLS Fellows - public seminars with candidates DESCRIPTION:Evolution and Biodiversity in the light of massive data details\n\n\n\nMeeting details\n\n\n\nWednesday\, June 19\, 2024 9:00-12:00 \n\n\n\nLocation: Lindahl-hall\, EBC Uppsala University. The meeting will also be on Zoom. Join us on: Zoom link >>   \n\n\n\nPasscode: DDLS \n\n\n\nSchedule\n\n\n\n9.00-9.15 Welcome9.15-9.45 Jennifer James: Investigating proteome trends: Evolution over huge timescales10.00-10.30 Julia V. Tavares: Forest sensitivity and resilience to climatic and hydrological changes10.45-11.15 Laura Antao: Elucidating biodiversity change in the Anthropocene11.30-12.00 Darrin Schultz: Chromosome structure as an evolutionary ledger URL:https://www.scilifelab.se/event/uppsala-university-ddls-fellows-public-seminars-with-candidates-evolution-and-biodiversity-in-the-light-of-massive-data/ CATEGORIES:Event ORGANIZER;CN="SciLifeLab Event":MAILTO:events@scilifelab.se END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Stockholm:20240827T120000 DTEND;TZID=Europe/Stockholm:20241001T120000 DTSTAMP:20260502T080510 CREATED:20240615T115304Z LAST-MODIFIED:20240615T115305Z UID:10001278-1724760000-1727784000@www.scilifelab.se SUMMARY:Data-Driven Life Sciences Course 2024 (Online) DESCRIPTION:Welcome to the Data-driven Life Sciences 2024 course\, where you will explore the intersection of data science\, artificial intelligence\, and life sciences to drive innovation and discovery. This fully online course culminates in an in-person hackathon\, fostering a vibrant community that gathers the DDLS and SciLifeLab members. \n\n\n\nThe 6 modules aim to introduce learners to computer-driven life sciences\, covering application areas in data-driven life sciences. Guest lecturers (DDLS Fellows\, SciLifeLab fellows\, and SciLifeLab facility training providers) will teach topics including technologies and analysis of data sets from proteomics\, transcriptomics\, biomolecular structure\, molecular dynamics simulations\, and various imaging techniques. These modules present\, analyze\, and discuss models of biological phenomena and related scientific breakthroughs based on such data analysis. \n\n\n\nRegistration\n\n\n\nAs prerequisites for the course\, we recommend that you have a look at the following resources: \n\n\n\n\nPlease have a look at the SciLifeLab Data-Driven Life Science (DDLS) initiative website to understand what data-driven life sciences are\, and how Sweden is investing in this area. Focus in particular on the concept of the data life cycle\, which is central in this class.\n\n\n\nWe will use Python as the main programming language in the computer lab\, so please make sure you know the basics of Python. \n\n\n\n\nFor the computer lab\, you will need a computer with internet access\, and make sure you have the following set up: \n\n\n\n\nInstall the latest browser\, e.g. Chrome\n\n\n\nRegister a Google account for the Google Colab access and use the Google Drive\n\n\n\nRegister a ChatGPT account (Note: No need to subscribe to the paid version of ChatGPT\, using the free version is sufficient for this course)\n\n\n\nRegister a Github account for versioning of the code\n\n\n\n\nLearning objectives:  \n\n\n\n\nDescribe the field of data-driven life sciences\n\n\n\nPresent an overview of various application areas\n\n\n\nProvide examples of applications and their associated analysis methods\n\n\n\nApply statistical and machine learning analysis to biological data sets\n\n\n\nFormulate models of biological phenomena\n\n\n\nPresent and review scientific literature in computer-driven life sciences\n\n\n\nReflect on the ethical consequences of data-driven life sciences\n\n\n\nPractice good data management\, including collection\, handling\, sharing\, and analysis\n\n\n\n\nFor questions\, contact the course leader Wei Ouyang at weio@kth.se URL:https://www.scilifelab.se/event/data-driven-life-sciences-course-2024-online/ LOCATION:Online event via Zoom CATEGORIES:Course END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Stockholm:20240924T120000 DTEND;TZID=Europe/Stockholm:20240925T120000 DTSTAMP:20260502T080510 CREATED:20240507T151251Z LAST-MODIFIED:20240925T061816Z UID:10001257-1727179200-1727265600@www.scilifelab.se SUMMARY:The Disruptive Role of Data and AI in the Life Sciences DESCRIPTION:A Joint Conference between DDLS\, WASP and WASP-HS\n\n\n\n\n\nThe conference will focus on different aspects of research where collaboration over scientific domains is essential and will explore the following topics: \n\n\n\n\nHow data- and AI-driven research is shaping the future of life science\n\n\n\nDevelopment of new approaches to human-in-the-loop technologies and their use\n\n\n\nThe need for studies at the intersection of society\, AI\, and data driven life sciences\n\n\n\n\n\n\n\n\nParticipants will have the opportunity to network\, be inspired by excellent international keynotes\, and take part of the latest research in Sweden. In addition to plenary keynotes\, the program will offer parallel sessions\, panel discussions\, mingle and poster sessions. \n\n\n\nPractical Details\n\n\n\nDates and times  \n\n\n\nSeptember 24\, 12:00 – September 25\, 12:30Registration is open from 11:00 on September 24. \n\n\n\nVenue: Wallenberg Conference Center\, Medicinaregatan 20 A\, Gothenburg \n\n\n\nInformation for registered poster \n\n\n\n• size of poster 90x 120 cm portrait format• posters can be hung on the 24th of September from 11:00 and should be done by 12:00• poster should be removed after the end of the conference on the 25th. You are responsible for your poster. Forgotten posters will not be saved.During the poster session 17:15-19 on the 24th of September we would appreciate if you are available by your poster for discussions and questions. During the Magnet mingle on the 25th you are also welcome to be by your poster. \n\n\n\nRegistration to the Conference\n\n\n\nRegister here \n\n\n\nThe registration is open until September 6. \n\n\n\nContact: ddls@scilifelab.se or info@wasp-sweden.org \n\n\n\nProgram\n\n\n\n24 September\n\n\n\n11:00 Registration opensPosters are to be hung up from 11:00 and should be done by 12:00. \n\n\n\n12:00 – 13:00 Lunch \n\n\n\nStart of conference \n\n\n\n13:00 – 13:15 Opening Program DirectorsChristofer Edling\, WASP-HSOlli Kallioniemi\, DDLSAnders Ynnerman\, WASPChair\, Rebecka Jörnsten WASP \n\n\n\n13:15-14:00 Keynote speaker Sunduz KelesIntegrative Approaches to Single-Cell Genomics for Personalized MedicineChair\, Rebecka Jörnsten WASP \n\n\n\n14:05- 14:50 Keynote speaker Ross KingThe Automation of ScienceChair\, Rebecka Jörnsten WASP \n\n\n\n14:50-15:20 Coffee \n\n\n\n15:20-16:20 Project presentation WASP DDLS (4 *15 min)Christopher Sprague\, Incorporating Stability Into Flow MatchingBjörn Wallner\, Improved protein structure prediction by adding noise at  inferenceHedvig Kjällström\, Unraveling the secrets of nature’s high-performance fiberAlexander Schliep and Pär Mattsson Molecular simulation and machine learning to delineate target binding of therapeutic oligonucleotidesChair\, Päivi Östling \n\n\n\n16:20-17:05 Project presentation WASP-HS DDLS (3* 15 min)Harald Hammarström\, Linguistic Diversity Through the Prism of BiodiversityStanley Greenstein\, AI in the Health Care Sector – Legal ChallengesSonja Aits\, Mapping the Nexus of Biodiversity\, Climate Change\, Human Society and Health using Large Language Models and other Data Science ApproachesChair\, Stefan Larsson \n\n\n\n17:15: – 19:00 Finger food and poster session \n\n\n\n25 September\n\n\n\n08:30-9:30 Project presentation WASP DDLS (4*15 min)Ingrid Hotz\, Tino Ebbers\, Characterization and visualization of cardiac spectral imaging dataSebastian Westenhoff\, cryoSPHERE: Single-particle heterogeneousreconstruction from cryo EMAndreas Kerren\, Visual Analytics for Enhancing Quality and Trust in Genome-wide Expression Clustering and AnnotationMinh Hoang Vu\, Anonymization of Data in Precision Medicine ResearchChair\, Olli Kallioniemi \n\n\n\n09:30-10:45 Magnet mingle including coffeeChair\, Rebecka Jörnsten and Christofer Edling \n\n\n\n10:45-11:30 Keynote Speaker: Klaus HøyerAll the data from everywhere all at once: data integration\, AI imaginaries\, and their unpredictable outcomesChair\, Christofer Edling \n\n\n\n11:30-12:15 Panel on common research challengesSunduz Keles\, Ross King\, Klaus Hoyer\, Andreas Kerren\, Tino EbbersModerators\, Rebecka Jörnsten and Stefan Larsson \n\n\n\n12:15 Closing remarks\, Program DirectorsChristofer Edling\, WASP-HSOlli Kallioniemi\, DDLSRebecka Jörnsten WASP \n\n\n\n12:30 Lunch to go \n\n\n\nKeynote Speakers\n\n\n\nSunduz Keles\n\nTitle: Integrative Approaches to Single-Cell Genomics for Personalized MedicineBio: Dr. Keles obtained her Ph.D. in Biostatistics from the University of California at Berkeley. After a year-long postdoctoral appointment at UC Berkeley\, she joined the Department of Biostatistics and Medical Informatics and the Department of Statistics at the University of Wisconsin\, Madison. She has twenty years of experience in developing statistical and computational methods for genomics\, including serving as an ENCODE PI\, and pioneering foundational statistical models for leveraging multi-mapping reads in high throughput sequencing data analysis (ChIP-seq\, Hi-C). \n\n\nHer research interests span developing statistical and computational methods for denoising and signal extraction from sequencing data and modeling of high dimensional data. Her computational approaches led to fundamental contributions on how GATA factors mediate transcriptional regulation in HSPCs and erythroid cells. Dr. Keles is an elected fellow of the American Statistical Association. \n\n\n\n\n\nKlaus Lindgaard Høyer\nTitle: All the data from everywhere all at once: data integration\, AI imaginaries\, and their unpredictable outcomesBio: Klaus Hoeyer is professor of Medical Science and Technology Studies at the Centre for Medical Science and Technology Studies\, University of Copenhagen. His research focuses on the links between policy\, practice and experience in relations to medical research and clinical practice. In recent years\, he has focused mainly on what he calls intensified data sourcing in healthcare and how it interacts with and changes the health services. This research is primarily financed by the European Research Council. \n\n\n\n\nRoss D. King\nTitle: The automation of scienceBio: Ross D. King did his PhD on applying machine learning to predicting protein structure at the Turing Institute in Glasgow. He has joint positions at Chalmers Institute of Technology\, and the University of Cambridge. He is one of the most experienced machine learning researchers in Europe. \n\n\n\nHis main research interest is the interface between computer science and science. He originated the idea of a ‘Robot Scientist’: integrating AI and laboratory robotics to physically implement closed-loop scientific discovery. His Robot Scientist ‘Adam’ was the first machine to autonomously discover scientific knowledge. His Robot Scientist ‘Eve’ is currently searching for drugs against neglected tropical diseases\, and COVID.  His other core research interest is DNA computing. \n\n\n\n\nProject Presenters\n\n\n\nAlexander Schliep\nTitle: Molecular simulation and machine learning to delineate target binding of therapeutic oligonucleotides \n\n\n\nBio: Alexander Schliep is the chair for Medical Bioinformatics at the Faculty of Health Sciences Brandenburg at Brandenburg Technical University Cottbus-Senftenberg\, with a secondary appointment at the University of Gothenburg and member of the WASP (Wallenberg AI\, Autonomous Systems and Software Program) research collegium. \n\n\n\nHis current research program is focused on machine learning and algorithmics for analyses of genomic data and nucleic acid-based therapeutics\, including machine learning for pan-genome graph analyses\, efficient analysis algorithms for large genomic datasets\, and federated\, privacy-preserving methods for training ML/AI models for oligonucleotide therapeutics. \n\n\n\n\nAndreas Kerren\nTitle: Visual Analytics for Enhancing Quality and Trust in Genome-wide Expression Clustering and Annotation \n\n\n\nBio: Prof. Dr. Andreas Kerren received his PhD degree in Computer Science from Saarland University\, Saarbrücken\, Germany. In 2008\, he achieved his habilitation (docent competence) from Växjö University\, Sweden. \n\n\n\nDr. Kerren is currently a Full Professor of Information Visualization\, Linköping University (LiU) and Linnaeus University (LNU)\, Sweden. He holds the Chair of Information Visualization at LiU and is head of the research group Information and Software Visualization at LNU. In addition\, he is an ELLIIT professor supported by the Excellence Center at Linköping–Lund in Information Technology and key researcher of the Linnaeus University Centre for Data Intensive Sciences and Applications. \n\n\n\nHis main research interests include several areas of information visualization and visual analytics\, especially visual network analytics\, text visualization\, and the use of visual analytics for explainable AI. \n\n\n\nHe has been editorial board member of a number of journals such as Information Visualization or Computer Graphics Forum\, has served as organizer/program chair at numerous conferences such as IEEE VISSOFT 2013/2018 or GD 2018\, and has edited a number of successful books on human-centered visualization. Dr. Kerren has published more than 200 peer-reviewed papers\, articles\, and book chapters. \n\n\n\n\nBjörn Wallner\nTitle: Improved protein structure prediction by adding noise at inference \n\n\n\nBio: Björn Wallner has been a faculty member at Linköping University since 2011 and a Professor in Bioinformatics since 2019. He obtained his Ph.D. in Bioinformatics from Stockholm University in 2005 and did postdoctoral work at the University of Washington from 2006-2008. \n\n\n\nHis research interests include protein structure prediction\, protein-protein interactions\, protein function\, disorder\, flexibility\, and dynamics. \n\n\n\n\nChristopher Sprague\nTitle: Incorporating Stability Into Flow Matching \n\n\n\nBio: Christopher Iliffe Sprague is a postdoctoral researcher at KTH Royal Institute of Technology and SciLifeLab\, working with Arne Elofsson and Hossein Azizpour on deep learning approaches for protein-protein interactions. He earned his PhD in robotics from KTH\, where he focused on developing efficient and trustworthy AI for critical robotic systems. \n\n\n\nCurrently\, as a postdoc\, Christopher is leveraging his robotics expertise to enhance inductive biases in deep generative models\, particularly for equilibrium generation tasks like molecular docking. His research interests include flow-based generative models\, hybrid dynamical systems\, and drug design \n\n\n\n\nHarald Hammarström\nTitle: Linguistic Diversity Through the Prism of Biodiversity \n\n\n\nBio: Harald Hammarström is Professor of General Linguistics atUppsala University. He has a background in both Computer Science andLinguistics. \n\n\n\nHe has a very broad linguistic interest spanning allareas of the world but specializing in minority languages in Papua\,Africa and South America. His research activities span fromdocumentary fieldwork in Papua\, Indonesia\, classical linguisticanalytic work\, typological databases\, and NLP for lesser-knownlanguages. \n\n\n\nHe is currently focussing on large-scale empirical andcomputational approaches to linguistic diversity\, genealogical/arealrelationships and language universals. \n\n\n\n\nHedvig Kjellström \nTitel: Unraveling the secrets of nature’s high-performance fiber \n\n\n\nBio: Hedvig Kjellström is a Professor in the Division of Robotics\, Perception and Learning at KTH Royal Institute of Technology\, Sweden\, and also affiliated with Swedish University of Agricultural Sciences\, Swedish e-Science Research Centre\, and Max Planck Institute for Intelligent Systems\, Germany. She received an MSc in Engineering Physics and a PhD in Computer Science from KTH in 1997 and 2001\, respectively\, and thereafter worked at the Swedish Defence Research Agency\, before returning to a faculty position at KTH. Her present research focuses on methods for enabling artificial agents to interpret human and animal behavior. These ideas are applied in the study of human aesthetic bodily expressions such as in music and dance\, modeling and interpreting human communicative behavior\, and the understanding of animal behavior and experiences. In order to accomplish this\, methods are developed for agents to perceive the world and build representations of it through vision. \n\n\n\nHedvig has received several prizes for her research\, including the 2010 Koenderink Prize for fundamental contributions in computer vision. She has written around 150 papers in the fields of computer vision\, machine learning\, robotics\, information fusion\, cognitive science\, speech\, and human-computer interaction. She is mostly active within computer vision\, where she is an Editor-in-Chief for CVIU\, a Program Chair for CVPR 2025\, and regularly serves as Area Chair for the major conferences.  \n\n\n\n\nIngrid Hotz\nTitle: Characterization and visualization of cardiac spectral imaging data \n\n\n\nBio: Ingrid Hotz is a professor at Linköping University in Sweden\, leading the Scientific Visualization group in the Department of Science and Technology. She holds an M.S. in theoretical physics from Ludwig Maximilian University\, Munich\, and a Ph.D. in computer science from the University of Kaiserslautern. Hotz has held research positions at the Institute for Data Analysis and Visualization (IDAV) at UC Davis\, the Zuse Institute Berlin\, and the German Aerospace Center (DLR). Since 2015\, she has been a professor at Linköping University and was named the Dr. Ram Kumar IISc Distinguished Visiting Chair Professor at the Indian Institute of Science in 2022. \n\n\n\nHer research focuses on scientific visualization and topological data analysis\, aiming to develop advanced visual analysis tools for complex datasets across various fields\, including engineering\, physics\, chemistry\, and medicine. She integrates methods from computer science and mathematics\, such as computer graphics and computational topology\, with a participatory design approach to ensure practical and relevant solutions. \n\n\n\n\nMinh Hoang Vu\nTitle: Anonymization of Data in Precision Medicine Research \n\n\n\nBio: Minh Vu is a postdoctoral researcher at IceLab\, Umeå University\, working under the supervision of Martin Rosvall and Beatrice Melin. Their research focuses on anonymizing and visualizing biobank data to facilitate meaningful insights and discoveries in disease understanding and treatment development. \n\n\n\n\nPär Matsson\nTitle: Molecular simulation and machine learning to delineate target binding of therapeutic oligonucleotides \n\n\n\nBio: Pär Matsson is Professor of Pharmacokinetics at the Sahlgrenska Academy\, University of Gothenburg\, and Scientific Director of OligoNova Hub – the SciLifeLab infrastructure for development of therapeutic oligonucleotides. \n\n\n\nHis research is centered on elucidating the molecular mechanisms of cellular and subcellular drug disposition\, and how they influence therapeutic effect. A particular focus is on the cellular disposition and effects of non-traditional drug modalities\, including therapeutic oligonucleotides and targeted protein degraders (PROTACs). \n\n\n\n\nSonja Aits\nTitle: Mapping the Nexus of Biodiversity\, Climate Change\, Human Society and Health using Large Language Models and other Data Science Approaches \n\n\n\nBio: Sonja Aits leads the “Cell Death\, Lysosomes and Artificial Intelligence” group at the Faculty of Medicine\, Lund University\, which works at the intersection of data\, life and sustainability science. Her group develops computational tools such as large language models for scientific text mining and computer vision models for histology and high-content microscopy and uses them to identify biological pathways and disease mechanisms in humans and other species as well as intervention strategies that promote human health\, biodiversity and sustainability. \n\n\n\nSonja helps coordinate AI Lund\, Lund University’s umbrella organization for AI-related research\, outreach and education\, and the profile area “Nature-based future solutions”. In addition\, she serves as study director of the COMPUTE research school\, where she has developed the PhD course program “AI in Medicine and Life Science”. She is also deeply engaged in open education and public outreach. \n\n\n\n\nStanley Greenstein\nTitle: AI in the Health Care Sector – Legal Challenges \n\n\n\nBio: Stanley Greenstein (Jur. Dr.) is an Associate Professor (Docent) in Law and Information Technology\, Faculty of Law\, Stockholm University. He is Chairman of the Board\, Swedish Law and Informatics Research Institute (IRI\, https://irilaw.org/)\, Chairman of the Board\, Foundation for Legal Information (Stiftelsen för rättsinformation) and a Digital Futures faculty member (https://www.digitalfutures.kth.se/about/). \n\n\n\nStanley’s primary academic focus is cross-disciplinary in nature and addresses the regulation of emerging digital technologies\, especially artificial intelligence (AI). His teaching\, research and participation in externally funded projects has revolved around the subject areas of ethics\, data protection\, sustainability and legal design. \n\n\n\n\nTino Ebbers\nTitle: Characterization and visualization of cardiac spectral imaging data \n\n\n\nBio: Tino Ebbers is a professor of physiological measurements at Linköping University\, with a focus on cardiac imaging\, modeling\, and simulation. He holds an MSc in Electrical Engineering from the University of Twente and a PhD in Biomedical Engineering from Linköping University. After completing his PhD\, he worked at Philips Medical Systems before returning to academia. He also served as a visiting professor at the University of California\, San Francisco. \n\n\n\nWith over 100 publications in leading scientific journals and numerous contributions to international conferences\, Tino Ebbers has made a significant impact through his multidisciplinary approach to merging technical research with clinical applications. He is best known for pioneering 4D flow MRI\, a breakthrough technology now widely used to study cardiovascular blood flow in both research and clinical settings. His contributions have greatly advanced cardiovascular imaging and led to major innovations in the diagnosis\, treatment\, and management of cardiovascular diseases. \n\n\n\n\nBackground\n\n\n\nSince 2021 the Wallenberg AI\, Autonomous Systems and Software Program (WASP) and the SciLifeLab and Wallenberg National Program for Data-Driven Life Science (DDLS) are collaborating through joint research projects with the ultimate goal of solving ground-breaking research questions across disciplines. In line with this\, the programs will now host the first\, joint annual conference where common research topics are highlighted. Additionally\, the increasingly important humanity and societal aspects of the research will be addressed through participation of the WASP-HS program (Wallenberg AI\, Autonomous Systems and Software Program- Humanity and Society). Read more about the different research programs here: \n\n\n\nDDLS\n\n\n\nWASP\n\n\n\nWASP-HS \n\n\n\nOpen Calls\n\n\n\nThe conference is an opportunity to find collaborators for the two open calls: \n\n\n\nWASP-DDLS: NEST projects https://wasp-sweden.org/calls/call-for-joint-wasp-and-ddls-nests/  \n\n\n\nWASP-HS-DDLS: Research Initiation Grants for Data-Driven Life Sciences and Society https://wasp-hs.org/open-call-research-initiation-grants-for-data-driven-life-sciences-and-society/  \n\n\n\n \n\n\n\n \n\n\n\n\n\n\n\n \n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n \n\n\n\nRead more\n\n\n\nRead more\n\n\n\nRead more URL:https://www.scilifelab.se/event/the-disruptive-role-of-data-and-ai-in-the-life-sciences/ LOCATION:Conference Centre Wallenberg\, Medicinaregatan 20A\, Gothenburg\, 413 90\, Sweden CATEGORIES:Event ATTACH;FMTTYPE=image/jpeg:https://www.scilifelab.se/wp-content/uploads/2024/05/DDLS_WASP_WP-1536x864-1.jpg END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Stockholm:20241007T120000 DTEND;TZID=Europe/Stockholm:20241008T150000 DTSTAMP:20260502T080510 CREATED:20240620T093344Z LAST-MODIFIED:20241003T140306Z UID:10001284-1728302400-1728399600@www.scilifelab.se SUMMARY:DDLS Symposium on Data-Driven Environmental Monitoring of Infectious Diseases DESCRIPTION:The DDLS research area Epidemiology and Biology of Infection invites you to its second in-person symposium. (The event is fully in-person only). The symposium will focus on promoting and enhancing data-driven environmental assessment for infectious diseases (including antibiotic-resistant bacteria) across various settings using diverse approaches. \n\n\n\nThe symposium will feature both local and international high-profile speakers in the field and will cover topics ranging from sewage surveillance\, monitoring of airborne infectious agents\, as well as environmental and animal disease monitoring for pathogens\, antimicrobial resistance and harmful substances. The symposium will also include more technical aspects of implementations as well as data-driven advancements and challenges. \n\n\n\nThere will also be a possibility to submit abstracts for short talks! \n\n\n\nPlease join us for this one-and-a-half-day symposium on 7-8 October 2024\, in Navet\, SciLifeLab’s meeting place in Uppsala\, to meet the research area Fellows\, the Expert Group and excellent researchers of the area. Engage in discussions\, enjoy refreshments\, and network with experts across a range of infectious disease monitoring topics! \n\n\n\nWelcome! \n\n\n\nScientific committeeAnna Székely (SLU)Johan Bengtsson-Palme (Chalmers) \n\n\n\nRegistration\n\n\n\nDeadline for abstract submission: 23 September (Extended deadline)Deadline to register to attend: 25 September \n\n\n\nIf seats are available and you register after September 25\, we can not accommodate allergies or special requirements and you will write your name tag upon arrival to the venue.. \n\n\n\nRegistration\n\n\n\n\n\n\n\nProgram\n\n\n\nDDLS symposium EBI_PROGRAM_3Download\n\n\n\n\n\n\n\n\n\nMembers of The Data-driven Epidemiology and biology of infection expert group:\n\n\n\nTom Britton\, Stockholm UniversityJoakim Dillner\, Karolinska Institutet and Karolinska Univ. HospitalTove Fall\, Uppsala UniversityBirgitta Henriques-Normark\, Karolinska InstitutetErik Kristiansson\, Chalmers University of TechnologyPatrik Medstrand\, Lund UniversityStaffan Svärd\, Uppsala UniversityOliver Billker\, chair (DDLS SG member) URL:https://www.scilifelab.se/event/ddls-symposium-on-data-driven-environmental-monitoring-of-infectious-diseases/ LOCATION:BMC Trippelrummet\, Husargatan 3\, entrance C11\, Uppsala\, Sweden CATEGORIES:Event ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2023/03/EBI_Icon.png END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Stockholm:20241009T090000 DTEND;TZID=Europe/Stockholm:20241011T163000 DTSTAMP:20260502T080510 CREATED:20240909T104734Z LAST-MODIFIED:20240910T082733Z UID:10001350-1728464400-1728664200@www.scilifelab.se SUMMARY:Data-Driven Life Sciences Hackathon DESCRIPTION:Join us at the DDLS Hackathon in person at SciLifeLab in Solna\, where participants will choose and collaborate on a range of provided projects. With the support of teaching assistants in a hands-on environment\, groups will innovate and develop solutions in the dynamic field of data-driven life science. \n\n\n\nDuring the three day hackathon\, participants will select a dataset and apply the skills and knowledge gained during the course (see link above for each module) to create AI models\, analyze the data\, and produce meaningful insights. At the end of the hackathon\, teams will present their achievements. \n\n\n\nEveryone affiliated with the DDLS programme or interested in data-driven life science is welcome to join–from PIs\, PhD students\, postdocs\, and facility experts/trainers. Participants will form pairs or small groups of 2-3 people on-site to work on projects\, exchange ideas and experiences\, and engage in pair programming. This collaborative environment will foster innovation and provide a unique opportunity to apply the concepts learned throughout the course to real-world problems in data-driven life sciences. \n\n\n\nWhat will you gain attending the hackathon?If you are to be selected to participate you will get the opportunity not only to work hands-on on a data-driven life science project\, but also to network with experts within the field of data-driven life science\, researchers and research infrastructure experts \n\n\n\nRegistration deadline:Monday\, September 30th\, 2024 \n\n\n\n \n\n\n\nRegistration\n\n\n\nThis hackathon is part of the 2024 DDLS course and will gather data-driven life science researchers (MSc students\, PhD students\, post-docs\, staff-scientists\, experts and group leaders). \n\n\n\n \n\n\n\nFor questions\, contact Wei Ouyang at weio@kth.se or traininghub@scilifelab.se URL:https://www.scilifelab.se/event/data-driven-life-sciences-hackathon/ LOCATION:Gamma 7 Lunchroom\, Tomtebodavägen 23A\, Solna\, 17121 CATEGORIES:Event END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Stockholm:20241017T090000 DTEND;TZID=Europe/Stockholm:20241017T170000 DTSTAMP:20260502T080510 CREATED:20240314T102017Z LAST-MODIFIED:20241011T115004Z UID:10001207-1729155600-1729184400@www.scilifelab.se SUMMARY:SciLifeLab Uppsala Site Day DESCRIPTION:The SciLifeLab site in Uppsala welcomes you to a full day of vibrant and inspiring science. During this event\, SciLifeLab Uppsala will highlight the research and infrastructure located in Uppsala. \n\n\n\nExperience the wide variety of research infrastructures at SciLifeLab Uppsala. Listen to talks from SciLifeLab/DDLS fellows. Join the panel discussion with the nationwide capability programs in Planetary Biology\, Precision Medicine\, and Pandemic Laboratory Preparedness. Enjoy poster sessions and exhibitions from SciLifeLab facilities. \n\n\n\nThe SciLifeLab Uppsala Site Day aims to foster discussions and interaction among participants. The event will be held exclusively on-site in Sal X\, which has a seating capacity of 221 people\, and will be streamed to Sal IX\, which can accommodate 141 people. Since the seats are limited\, remember to cancel if you cannot attend. \n\n\n\nAll attendees are invited to enjoy fika\, lunch\, and mingling sessions. Please note that no Zoom link will be available. \n\n\n\nRegistration\n\n\n\nRegistration closes on October 14 at 09:00. \n\n\n\nRegistration\n\n\n\nIf you have questions\, please contact events@scilifelab.se \n\n\n\n\n\n\n\nProgram\n\n\n\nSciLifeLab Day Uppsala_Program_v4.0Download\n\n\n\n\n\n\n\nExhibition List\n\nU-Print\, 3D printing facility Paul O’Callaghan\n\n\n\nDanioReadout Beata Filipek-Gorniok\n\n\n\nNMR-UppsalaRuisheng Xiong\n\n\n\nMicrofluidicsMaria Tenje\n\n\n\nAffinity Proteomics UppsalaMikael Åberg\n\n\n\nGenomics PlatformSusanne Hellstedt Kerje\n\n\n\nBioImage Informatics Anna KlemmBioinformatics (NBIS/ELEXIR-SE)\,Bengt Persson\n\n\n\nChemical Biology Consortium Sweden Uppsala Jordi Carreras Puigvert\n\n\n\nClinical Genomics UppsalaMalin Melin\n\n\n\nDrug Discovery and Development Platform Rebecka Klintenberg\n\n\n\nSpatial Mass SpectrometryAnna Nilsson\n\n\n\nUppsala International HubCharlotte Walker\n\n\n\nTesta CenterAlexandra Patriksson\n\n\n\nSciLifeLab CapabilitiesPrecision Medicine Capability\, Eva Berglund. Pandemic Laboratory Preparedness Capability\, Alice Sollazzo. Planetary Biology Capability\, Anabella Aguilera\n\n\n\nEATRIS Ulrika BäckmanInnovation coaching Kerstin Ekelöf\, UU Innovation\, Liza Nilsson\, UU Innovation\n\n\n\nUppsala Clinical Research Center (UCR)\, Maria Sörby\n\n\n\nSciLifeLab Data Centre and Data Science Node in Evolution and Biodiversity\, Angela Fuentes Pardo\n\n\n\nSciLifeLab\, Training Hub\, Data-driven Life Science Program (DDLS) supported by KAW and SciLifeLab\, Hampus Pehrsson Ternström\n\n\n\n\n\nPosters and Flash Talks\nWe have reserved space for selected SciLifeLab/DDLS fellow PhD students\, eSSENCE PhD students to bring a scientific poster. Four submitted abstracts have been selected for a 5-minute Flash Talk. The selected Flash Talks are highlighted. \n\n\n\nInstructions \n\n\n\nMount your poster during the Coffee & Registration at 08:30-09:00\, poster presentation during the lunch mingle. \n\n\n\nThe poster screens are portrait oriented\, 103×143 cm. \n\n\n\nPoster #Poster title and presenter1Investigating Islet Vasculature Alterations in Type I DiabetesCasian-Simon Aioanei – FLASH TALK2Optimal effect estimation in genome-wide association studies with censored biomarker measurements in large-scale biobanksYaqi Deng – FLASH TALK3Loss of chromogranin A and catestatin affect islet composition and neurotransmitters in the pancreasDali Epremidze – FLASH TALK4Chemoselective Primer Extension for Sequencing in Fixed and Living CellsChengxiang Yuan5Unraveling the Alzheimer’s Puzzle: The Role of ApoE4\, Mitochondria\, and Lipid Metabolism in neuronal settingSona Hakhverdyan6Adaptive Robust Learning using Latent Bernoulli VariablesAleksandr Karakulev7Deep Learning with Big Data for Genetic EpidemiologyMax Kovalenko8Strained Cyclooctynes with Photocages for Subcellular 3D Photolithographic BarcodingAlfred Larsson9The evolution of gene CNVs in C. rubellaFreja Lindstedt10Variational Approaches for Simulation-Based InferenceMayank Nautiyal11Deep Learning-driven Survival Prediction In Non-small Cell Lung Cancer Using Multiplex Immunofluorescent ImagingLove Nordling12Detection of protein-protein interactions by bio-orthogonal fluorogenic proximity probesAndreas Torell – FLASH TALK13Copy number variations and adaptation along environmental gradients in Picea abies and P. obovataQiujie Zhou\n\n\n\n\n \n\n\n\nOrganizers\n\n\n\n\nEva Tiensuu Janson\, chair SciLifeLab Uppsala committee\, Integration Director\n\n\n\nAristidis Moustakas\, SciLifeLab Uppsala committee\n\n\n\nMikael Widersten\, SciLifeLab Uppsala committee\n\n\n\nJenny Alfredsson\, SciLifeLab Uppsala committee\n\n\n\nAnna Dimberg\, SciLifeLab Uppsala committee\n\n\n\nTitti Ekegren\, project coordinator\, SciLifeLab Uppsala committee URL:https://www.scilifelab.se/event/scilifelab-day-uppsala/ LOCATION:University Main Building\, Biskopsgatan 3\, Uppsala\, 75310 CATEGORIES:Event ATTACH;FMTTYPE=image/jpeg:https://www.scilifelab.se/wp-content/uploads/2024/02/C13089-scaled.jpg END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Stockholm:20241024T100000 DTEND;TZID=Europe/Stockholm:20241024T123000 DTSTAMP:20260502T080510 CREATED:20241002T123645Z LAST-MODIFIED:20241004T071259Z UID:10001367-1729764000-1729773000@www.scilifelab.se SUMMARY:Discover services for data-driven life science DESCRIPTION:Welcome to join SciLifeLab Data Centre and SciLifeLab Data Management for “Discover services for data-driven life science“-  an overview of data-driven services\, tools\, and support aimed at the fellows community. The event will also include a feedback session to help SciLifeLab Data Centre best support your specific research needs. Share your views about your current and future research needs\, e.g. state-of-the-art services that would further your research or the general research of your field\, currently not available on the SciLifeLab Data Platform. \n\n\n\nWhen: Oct 24\, 10-12.30 CET (Zoom)Target group: Scilifelab Fellows\, DDLS Fellows\, and interested participants \n\n\n\n \n\n\n\nAgenda \n\n\n\n10.00-10.10   Welcome   Johan Rung\, Head of SciLifeLab Data Centre \n\n\n\n10.10-10.35   Open Science 101 Chris Erdmann\, Head of Open Science \n\n\n\n10.35-11.00   SciLifeLab Data Management services and support Angela Fuertes-Pardo\, Data Steward\, SciLifeLab Data Centre \n\n\n\n11.00-11.05  Coffee break \n\n\n\n11.05-11.30   How to get access to Compute\, Storage\, and Hosting to support your research\, speaker TBA \n\n\n\n11.30-12.30   Feedback session: Share your needs for data-driven life science services and tools. Moderators: Johan Rung\, Head of SciLifeLab Data Centre\, and Niclas Jareborg\, NBIS \n\n\n\n \n\n\n\nFor additional information please contact SciLifeLab Data Centre at datacentre@scilifelab.se URL:https://www.scilifelab.se/event/discover-services-for-data-driven-life-science-2/ CATEGORIES:Event LOCATION:https://uu-se.zoom.us/j/63809262140 END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Stockholm:20241105T103000 DTEND;TZID=Europe/Stockholm:20241105T170000 DTSTAMP:20260502T080510 CREATED:20240426T130948Z LAST-MODIFIED:20241024T073225Z UID:10001244-1730802600-1730826000@www.scilifelab.se SUMMARY:Postponed! New hybrid approaches to Precision Medicine: machine learning\, generative AI\, and digital twins DESCRIPTION:Workshop postponed to the spring – date to be decided!\n\n\n\n \n\n\n\nIf you have questions or suggestions regarding symposia program\, please feel free to contact the chair of the program committee at gunnar.cedersund@liu.se. \n\n\n\nWe look forward to welcoming you to Linköping in the spring 2025! \n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\nMembers of The Data-driven Precision Medicine & Diagnostics expert group:Gunnar Cedersund\, Linköping UniversitySven Nelander\, Uppsala UniversityLars Klareskog\, Karolinska InstitutetJohan Trygg\, Umeå UniversityPatrik Georgii-Hemming\, Karolinska InstitutetPäivi Östling\, KI (adj. SciLifeLab Precision Medicine Capability lead)Francis Lee (adj. WASP-HS representative in DDLS)David Gisselsson Nord (adjunct as GMS representant)Janne Lehtiö\, chair (DDLS SG member) URL:https://www.scilifelab.se/event/new-hybrid-approaches-to-precision-medicine-machine-learning-generative-ai-and-digital-twins/ CATEGORIES:Event ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2024/04/PMD_web.png END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Stockholm:20241108T140000 DTEND;TZID=Europe/Stockholm:20241108T150000 DTSTAMP:20260502T080510 CREATED:20241028T075658Z LAST-MODIFIED:20250115T125101Z UID:10001387-1731074400-1731078000@www.scilifelab.se SUMMARY:Swedish Reference Genome Portal Launch DESCRIPTION:Join us for the official launch of the Swedish Reference Genome Portal. This free service is developed and maintained by the DDLS Data Science Node in Evolution and Biodiversity (DSN-EB) team as part of the SciLifeLab Data Platform\, operated by the SciLifeLab Data Centre. At this event\, we will demonstrate how the Genome Portal reduces barriers to the visualisation and interpretation of genome data studied in Sweden\, while facilitating collaboration\, showcasing researchers’ work\, and promoting Open Science and FAIR data sharing. \n\n\n\nThe Swedish Reference Genome Portal is a web platform for showcasing\, aggregating\, and visualising non-human eukaryotic genome assemblies and genome annotations (co-)produced by researchers affiliated with Swedish institutions. The Genome Portal aims to: \n\n\n\n\nHighlight and showcase genome research conducted in Sweden.\n\n\n\nLower barriers to accessing\, visualising\, and interpreting genome data.\n\n\n\nPromote the publication of genomic annotations\, which are rarely shared.\n\n\n\nEnsure all data displayed on the Genome Portal aligns with FAIR principles and is available in public repositories.\n\n\n\n\nThe DSN-EB team comprises system developers\, data stewards\, and bioinformaticians affiliated with SciLifeLab Data Centre and the National Bioinformatics Infrastructure Sweden (NBIS)\, based at Uppsala University and the Swedish Museum of Natural History. \n\n\n\nThis service is supported by SciLifeLab and the Knut and Alice Wallenberg Foundation through the Data-Driven Life Science (DDLS) program\, as well as by the Swedish Foundation for Strategic Research (SSF). \n\n\n\nRegistration\n\n\n\n \n\n\n\nAgenda\n\n\n\n2:00-2:10 pmWelcome and introduction\, Henrik Lantz\, NBIS2:10-2:45 pmOverview of the Swedish Reference Genome Portal Introduction and live demo\, Daniel Brink\, SciLifeLab Data CentreTechnical implementation\, Rory Crean\, SciLifeLab Data CentreFeatures that boost and facilitate researchers’ work\, Angela P. Fuentes-Pardo\, SciLifeLab Data Centre2:45-3:00 pmQ&A\n\n\n\nRegistration will be open until the day of the event (November 8th\, 2024) at 12:00 CEST. \n\n\n\nThis event will be recorded and made available on the SciLifeLab Youtube channel. \n\n\n\nFor more information\, please contact dsn-eb@scilifelab.se. URL:https://www.scilifelab.se/event/swedish-reference-genome-portal-launch/ LOCATION:Online event via Zoom CATEGORIES:Event END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Stockholm:20241114T133000 DTEND;TZID=Europe/Stockholm:20241114T153000 DTSTAMP:20260502T080510 CREATED:20240904T150417Z LAST-MODIFIED:20241014T130734Z UID:10001342-1731591000-1731598200@www.scilifelab.se SUMMARY:DDLS Annual Conference 2024 workshops DESCRIPTION:During the second day of the DDLS Annual conference 2024 participants will have an opportunity to attend one of the workshops. The workshops are directed at researchers in data-driven life science in all career stages. \n\n\n\nEach workshop has a limited number of seats\, on the first come first served basis. Those registered after the limit is reached will be placed on the waiting list. \n\n\n\nThe workshops will take place in various rooms of the main venue of the conference – Hilton Slussen. All workshops start at 13:30 but end at various times. Coffee/tea and fika will be served during the workshops. \n\n\n\nFeel free to email datacentre@scilifelab.se with any questions. \n\n\n\nWorkshops\n\n\n\nHands-on with Large Language Models\n\n\n\nHeld by: Ola Spjuth (UU\, SciLifeLab) and AI data engineers at SciLifeLab Data Centre \n\n\n\nWhere and when: November 14\, 2024 at 13:30-15:00\, room Sofokles \n\n\n\nDescription: Tools based on Large Language Models (LLMs) such as ChatGPT\, Microsoft Copilot\, Perplexity\, etc. are now widely used in various tasks such as drafting and editing texts\, analyzing data\, writing and troubleshooting code\, creating images\, etc. This workshop is aimed at researchers who never used or only recently started using LLM-based tools and would like to learn more. We will start with a theoretical introduction of how LLMs work and in which tasks they can be especially useful. Workshop participants can then choose from a number of hands-on exercises that they can complete on their own laptops. We will be available to help and answer questions. \n\n\n\n\n\n\n\nPackaging and sharing data science applications as Docker container images\n\n\n\nHeld by: Data Engineers at the SciLifeLab Data Centre. \n\n\n\nWhere and when: November 14\, 2024 at 13:30-15:30\, room Platon \n\n\n\nDescription: This workshop is aimed at life science researchers who want to share data science applications such as apps built with R Shiny\, Plotly Dash\, Gradio\, Streamlit etc. publicly or with colleagues. Docker container images are a powerful tool for packaging and sharing applications and analyses widely used in both industry and academia. During the workshop we will first present the basics of Docker and how to build Docker container images. Building on this knowledge participants will then carry out hands-on exercises on their own laptops while we will be available to help. Finally\, we will also demonstrate how to publish applications packaged as Docker images on SciLifeLab Serve (https://serve.scilifelab.se) and make them available on the web with a URL (for example\, to be used in research papers or other output). SciLifeLab Serve is a service available free of charge to all life science researchers in Sweden. The participants are welcome to bring their own data science applications\, and we can help packaging them on the spot. \n\n\n\n\n\n\n\nHow to boost your career using Open Science\n\n\n\nHeld by: Joanna Sendecka\, Suné Joubert\, & Parul Tewatia\, SciLifeLab Data Center; Ineke Luijten\, SciLifeLab Training Hub \n\n\n\nWhere and when: November 14\, 2024 at 13:30-15:30\, room Eros \n\n\n\nDescription: Over the past years\, the evaluation of researchers by institutions\, journals\, and funders has been expanded to encompass more than just publication metrics. This workshop is aimed at researchers that want to learn how to use new researcher evaluation criteria to boost their careers by increasing visibility of and gaining credit for all of their research outputs. In this workshop\, we will discuss past\, current\, and future evaluation criteria\, and will then provide hands-on exercises to demonstrate how researchers can get and give credit for a range of research outputs\, including datasets\, software\, code\, public engagement\, and training. We will do this in adherence with DORA and CoARA principles\, and the use of a variety of tools\, such as CRediT taxonomy and ORCID. \n\n\n\n\n\n\n\nRegistration\n\n\n\nSince there is a limited number of seats in each workshop please sign up only if you intend to attend. \n\n\n\nRegister to join workshops URL:https://www.scilifelab.se/event/ddls-annual-conference-2024-workshops/ LOCATION:Hilton Slussen\, Guldgränd 8\, 104 65\, Stockholm CATEGORIES:Event ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2023/03/New_Clower_black_English.png ORGANIZER;CN="SciLifeLab Data Centre":MAILTO:datacentre@scilifelab.se END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Stockholm:20250113T130000 DTEND;TZID=Europe/Stockholm:20250115T140000 DTSTAMP:20260502T080510 CREATED:20240626T141219Z LAST-MODIFIED:20250109T070825Z UID:10001290-1736773200-1736949600@www.scilifelab.se SUMMARY:Evolution in Sweden 2025 DESCRIPTION:Evolution in Sweden is a biannual meeting\, which broadly gathers evolutionary biologists working in Sweden. \n\n\n\nThe meeting is aimed to be a broad meeting on every aspect of evolutionary biology and all forms of life on earth. However\, please note that the meeting is primarily (though not exclusively) for scientists active in Swedish academic departments. We also actively encourage younger researchers active in Sweden to present their research in this forum. \n\n\n\nThe Evolution in Sweden conference is organized together with the DDLS Evolution and Biodiversity research area\, within the Data-driven Life Science (DDLS) program\, part of a 12-year SEK 3.1 billion initiative from the Knut and Alice Wallenberg Foundation. We encourage researchers working with analysis of large data sets in the fields of evolution and biodiversity to attend.  \n\n\n\nStarts on January 13 at 13:00 and ends on January 15 at 14:00 \n\n\n\nVenue: Room C4\, C building\, Campus Valla\, Linköping University\, Hans Meijers väg 12\, Linköping. \n\n\n\nRegistration is from 9.30 until 13.00 outside the lecture hall on the 13th January. \n\n\n\n\n\n\n\nImportant information to participants: \n\n\n\nWelcome Reception \n\n\n\nRegistration and check-in from 09:30 to 13:00 on Monday\, January 13\, followed by lunch. Lunch is paid for by the attendees\, but we have booked a restaurant next to the venue. There is no registration fee\, but fika will be provided. Lunch\, Dinner\, and Hotel are not included in the registration. \n\n\n\nPoster presenters \n\n\n\nWe kindly ask you to hang your poster in the foyer-area outside C4 during the registration; pins will be provided. Make sure to stand by your poster during the odd or even poster session depending on your abstract/poster number. Odd abstract numbers on Jan 13 and even numbers on Jan 14. The size of each poster space is 85 x 190 cm\, so posters can be up to the standard A0 format (1189 x 841 mm) in size. \n\n\n\nOral presenters \n\n\n\nPlease upload your talk to the Dropbox directory you will be invited to in a separate email. Please ensure your presentation is uploaded by the evening before your scheduled talk. Name the file using the following format: Day_Time of your slot_Name.pdf (or .ppt). Example: Tuesday_1345_Berger.pdf. \n\n\n\nTechnical Considerations: The lecture hall computers run on Windows. If you are using a Mac\, we recommend saving your presentation in .pdf format to avoid formatting issues. A manned table will be set up near the registration desk outside the conference hall\, where you can check your presentation in advance (fonts\, animations etc). \n\n\n\nLunch \n\n\n\nThe cost of lunch is at everyone’s own expense. Lunch venue is booked at the University restaurant Kårallen\, situated in the next building down from the C-building (two minutes walk from the lecture hall). \n\n\n\nSocial activities \n\n\n\nWe have a poster session on the 13th and 14th outside the lecture theatre\, and have also highlighted a conference pub in town (O’Leary’s). This was picked because of its size\, but we don’t have any actual reservations (but it is pretty huge on the inside). It is located in the main square (Storatorget)\, and several other pubs are also located on the main square or on the next street (Ågatan) for those who want to meet for a drink in the evenings. \n\n\n\nWelcome! \n\n\n\nThe Evolution in Sweden Linköping organizing committee \n\n\n\nDominic Wright (chair)\, Rie Henriksen\, Per Jensen\, Urban Friberg and Krzysztof Bartoszek \n\n\n\nProgram\n\n\n\nProgram\n\n\n\nConference book\n\n\n\nAbstract book Evolution in Sweden 2025 v6Download\n\n\n\nRegistration\n\n\n\nRegister here\n\n\n\nTo avoid empty seats\, registration will remain open until the event begins. If we reach full capacity\, a waiting list will be activated. Sign up for the waiting list\, and you will automatically receive an email when a spot becomes available. You must accept within 24h to secure the spot. If you decline\, the offer will go to the next person on the waiting list. \n\n\n\nMake sure to cancel your registration if you cannot attend the conference. To cancel: Search for “Confirmation: Evolution in Sweden 2025” in your inbox and cancel via that Cancellation link in your individual Confirmation letter. \n\n\n\n \n\n\n\nPlenary speakers\n\n\n\nTom Gilbert – Domestication hologenomics – how did our ancestors tame the wolf?\nUniversity of Copenhagen\, Denmark \n\n\n\nComparisons of the genomes of contemporary domestic animals and plants with those of their wild relatives\, have provided a wealth of insights into not only when and where our ancestors started the process\, but also what specific genetic variants are key to modern phenotypes. Furthermore\, once coupled to palaeogenomic data\, such datasets can also even reveal the order in which such variants arose\, shedding further insights into the process itself. However\, while there is no doubt that we have learnt much about domestication in general\, and indeed for most domestic species we can clearly document the genetic basis of why the end product differs from the start\, I argue that there may be certain processes that were involved that have been largely overlooked\, in particular related to the so-called hologenome. \n\n\n\nBiography: \n\n\n\nTom Gilbert is Professor of Palaeogenomics at the University of Copenhagen\, Professor II at NTNU University Museum\, and Director of the DNRF Center for Evolutionary Hologenomics. He holds a PhD in the study of ancient DNA from the University of Oxford\, and has been active in both trying to develop methods to both expand the potential of ancient DNA to our understanding of the past\, as well as more recently leading research aimed at revisiting our understanding of ecological and evolutionary processes using hologenomic techniques – ie the integrative approach of combining host genomes with those of their microbiome. \n\n\n\n\nKees Van Oers – The epigenetics of Animal Personality\nNetherlands Institute of Ecology/ Wageningen University\, The Netherlands \n\n\n\nEpigenetic mechanisms are those molecular mechanisms that affect gene expression without changing the DNA sequence. The value of epigenetic mechanisms is increasingly recognized\, also in relation to questions in ecology and evolution. However\, epigenetic research related to behavioural variation in the natural habitat is still in its infancy. The flexible nature of epigenetic marks opens the possibility that such changes are adaptive\, while at the same time may simply be the consequence of environmental variation. Hence\, changes in epigenetic marks can function as switches in order to help an organism develop\, as signals of aging via accumulation of methylation over time\, but they also may aid organisms to cope with changing circumstances throughout their lifetime. In this presentation\, I use data of our great tit system to show examples of how tissue and cell-specific epigenetic patterns\, mainly focusing on DNA methylation\, may affect behavioral phenotypes such as exploratory behavior and reversal learning performance. I discuss what the role is of epigenetic mechanisms for behavioral adaptation to changing environments. \n\n\n\nBiography: \n\n\n\nKees van Oers is an evolutionary behavioural ecologist. He currently holds a chair in Animal Personality at Wageningen University and is senior scientist at the Netherlands Institute of Ecology (NIOO-KNAW). His research focuses on explaining the causes and consequences of individual variation in animal behaviour\, mainly cognitive and animal personality traits. He does this from an ecological and evolutionary point of view\, at the crossroads between behavioural ecology and behaviour genetics. His goal is to find answers to fundamental and strategic questions related to individual responses to changing environments. This is relevant since the world and therefore the environment is constantly changing partly due to human influences affecting biodiversity at all functional levels. \n\n\n\n\nSusan Johnston – The causes and consequences of sex differences in recombination rates.\nInstitute of Ecology and Evolution\, School of Biology\, The University of Edinburgh\, UK \n\n\n\nThe rate of meiotic recombination often shows large differences between the sexes. It can be strongly female-biased (humans)\, strongly male-biased (macaques/sheep) or somewhere in between. Understanding why this happens is key to understanding the evolution of recombination rates\, yet the causes and consequences of this phenomenon remain unknown. This talk will focus on our most recent work in house sparrows (Passer domesticus)\, with broader context from work in mammals and fish. We use genomic data in large pedigrees to characterise individual recombination rates and landscapes to: (a) investigate the heritability and genomic basis of variation in recombination rates; (b) identify genomic correlates with fine-scale sex-differences in recombination landscapes; and (c) use genomic prediction approaches to understand the relationship between recombination and fitness within each sex. Our work provides a foundation for broader understanding of the vast diversity of recombination rates in eukaryotic genomes. \n\n\n\nBiography: \n\n\n\nSusan Johnston is an evolutionary quantitative geneticist based at the University of Edinburgh\, Scotland\, where she is a Senior Lecturer and Royal Society University Research Fellow. Her research centres on using genomic information to understand selection and evolution in both wild and domesticated populations. At the moment\, her group focusses on questions related to genomic signatures of sexual conflict\, the maintenance of genetic variation in immunity\, and the causes and consequence of recombination landscape variation. She does this by taking advantage of long-term ecological datasets and deep pedigrees with genomic data in mammals\, birds and fish. \n\n\n\n\nIf you have questions\, feel free to contact the organizer\, Dominic Wright\, dominic.wright@liu.se\, Professor in Genetics\, IFM Biology\, Linköping University. Regarding DDLS-related issues\, you can ask Matthews Webster or events@scilifelab.se. URL:https://www.scilifelab.se/event/evolution-in-sweden-2025/ LOCATION:Linköping University\, Campus Valla\, Hans Meijers väg 12\, 583 29\, Linköping CATEGORIES:Event ATTACH;FMTTYPE=image/jpeg:https://www.scilifelab.se/wp-content/uploads/2024/06/EvoInSwedenSmallLogo.jpg END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Stockholm:20250203T080000 DTEND;TZID=Europe/Stockholm:20250204T170000 DTSTAMP:20260502T080510 CREATED:20240529T070047Z LAST-MODIFIED:20250911T092745Z UID:10001269-1738569600-1738688400@www.scilifelab.se SUMMARY:Infection Biology Across Scales DESCRIPTION:An EMBL-SciLifeLab-MIMS workshop on infection\n\n\n\nThe European Molecular Biology Laboratory (EMBL)\, SciLifeLab and the Laboratory for Molecular Infection Medicine Sweden (MIMS) invite you to an in-person workshop on infection biology on 3-4 February 2025 in Umeå.  \n\n\n\nThe workshop will focus on exploring complementary platforms and capabilities of the three organizations in light of the most important scientific challenges facing infection research. We are also eager to foster exchange between EMBL and Swedish scientists more widely\, with a particular emphasis on the next generation of future research leaders from Swedish excellence initiatives who are at a similar career stage as EMBL group leaders.  \n\n\n\nPlease join us for this one-and-a-half-day workshop to meet the researchers\, engage in discussions\, network with experts across a range of infectious disease research and related services and platforms\, accompanied by refreshments!  \n\n\n\nzoom link\n\n\n\nregister\n\n\n\nProgram\n\n\n\n3 February 2025\, Rotundan 11:30Soft landing with lunch\, Brashörnan13:00Welcome and opening wordsOliver Billker\, MIMS Director\, Jan Ellenberg\, SciLifeLab Director\, and Maria Bernabeu\, EMBL\, Infection Biology Transversal Theme13:15Session I: From pathogen genomes to pandemic preparedness  Chairs: Stefan Bertilsson\, SciLifeLab/SLU and John Lees\, Uppsala UniversityIntroductionStefan Bertilsson\, SciLifeLab/SLU and John Lees\, Uppsala University13:20Resources for assembly and annotation of metagenomes    Rob Finn\, EMBL-EBI Tools for modelling and epidemiology of pathogens John Lees\, EMBL-EBI 13:45Resolving microbial genomes in complex communities at the single-cell level  Laura Carroll\, SciLifeLab/Umeå University and MIMS 14:05Coffee Break14:20Functional annotation of malaria parasite genomes at scaleEllen Bushell\, Umeå University and MIMS14:40A Large Language Model for studying bacterial genome architecture\, population structure and epidemiologySam Horsfield\, EMBL-EBI 15:00Viral metagenomicsTobias Allander\, Karolinska Institutet/SciLifeLab15:20Meet the facilities & infrastructures  Venue: Galaxen. Coffee and cake served. 16:00Session II: Imaging infection – from organisms to structure  Chairs: Maria Bernabeu and Lars-Anders Carlson IntroductionBreaking and entering: capturing T. gondii invasion by multi-modal imaging Simone Mattei\, EMBL16:25Bioengineered models for malaria pathogenesis researchMaria Bernabeu\, EMBL16:40Resolving Enterobacterial Pathogenesis by Gut Organoid ImagingMikael Sellin\, SciLifeLab/Uppsala University16:55Coffee Break17:10Structural Biology with Neutrons at the European Spallation SourceEsko Oksanen\, European Spallation Source (ESS) and Lund University17:30Replication organelles of arboviruses through the lens of a cryo-electron microscopeLars-Anders Carlson\, Umeå University and MIMS17:50Mechanistic insight into mycobacterial Type VII SecretionMatthias Wilmanns\, EMBL 18:15Bus transfer to Bildmuseet (contemporary art museum) for social activity; guided introduction followed by walk to see exhibition 20:00Dinner in Bildmuseet\n\n\n\n4 February 2025\, Rotundan 08:30Soft landing with coffee09:00Session III: Microbiome  Chairs: Luisa Hugerth\, SciLifeLab/Uppsala University and Rob Finn\, EMBL-EBIIntroduction Leveraging large human cohorts to understand links between the gut microbiome and healthTove Fall\,  Uppsala University09:25Systems ecology of the human microbiome in health and disease: from molecules to mechanismsPaul Wilmes\, University of Luxemburg09:50Facilitating Microbial Research with High-Throughput Approaches & Automation Alexandra Koumousti\, EMBL 10:05Coffee Break10:20The effects of bugs and drugs during early lifeNele Brusselaers\, Karolinska Institutet10:35Drug resistance and metabolism of gut commensals at strain resolutionMariia Beliaeva\, EMBL   10:50Dietary suppression of Muc2-dependent host-microbiota mutualism in the small intestineGeorge Birchenough\, University of Gothenburg11:05Mechanistic insight into diet-dependent mucus modulation by the gut microbiotaBjörn Schröder\, Umeå University and MIMS  11:20Lunch  12:15Session IV: Antimicrobial resistance  Chairs: Nassos Typas and Linus Sandegren12:20Heteroresistance – a complex and insidious antibiotic resistance phenotypeDan Andersson\, Uppsala University12:45Rapid imaging-based antibiotic susceptibility testing for UTI\, sepsis\, and tuberculosisJohan Elf\, SciLifeLab/Uppsala University13:10Coffee Break13:25Breaking intrinsic antibiotic resistance by targeting bacterial defense mechanismsMichaela Wenzel\, Chalmers13:45Gut microbiota (counter)-selects for antibiotic resistant strains at a personalized mannerMichael Knopp\, EMBL14:05Reflection and Closing wordsAudience\, Session Chairs\, and Oliver Billker\, MIMS14:30Departure\n\n\n\nOrganizers\n\n\n\n\nSciLifeLab \n\n\n\nSciLifeLab Pandemic Laboratory Preparedness Capability\n\n\n\nSciLifeLab & Wallenberg National Program for Data-Driven Life Science\n\n\n\nMIMS\n\n\n\nEMBL\n\n\n\n\nCommittee\n\n\n\nMaria Bernabeu\, EMBLNassos Typas\, EMBLOliver Billker\, Nordic EMBL Partnership\, Umeå University\, MIMS\, DDLSUlf Ribacke\, Karolinska Institutet\, SciLifeLab Pandemic Laboratory Preparedness URL:https://www.scilifelab.se/event/infection-biology-across-scales-an-embl-scilifelab-mims-workshop-on-infection/ LOCATION:Rotundan\, Umeå University\, Universums Gränd 4\, Umeå\, Sweden CATEGORIES:Event END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Stockholm:20250306T100000 DTEND;TZID=Europe/Stockholm:20250306T160000 DTSTAMP:20260502T080510 CREATED:20250114T125459Z LAST-MODIFIED:20250304T151829Z UID:10001453-1741255200-1741276800@www.scilifelab.se SUMMARY:Automation of research processes with LLMs and AI DESCRIPTION:SciLifeLab is thrilled to invite you to the symposium ‘Automation of research processes with LLMs and AI’\, to be held on March 6 at Eva & Georg Klein lecture hall\, Biomedicum\, Karolinska Institutet Campus Solna. \n\n\n\nThe purpose of the symposium is practical knowledge sharing\, inspiration\, and reflection on the future of scientific processes in life sciences and health research. Academic\, healthcare\, and industry researchers working within the broad life sciences are welcome to attend. \n\n\n\nMore and more AI-based tools are currently being integrated in scientific research processes\, from simple academic text editing tools to automated labs empowered by large language models (LLMs) running experiments and making scientific conclusions. For researchers in life sciences and health\, developments in the AI technologies are important because of the high potential\, large monetary investments\, but also expectations about future breakthroughs.This one-day event offers an opportunity for the researchers to hear about specific examples of incorporating Large Language Models (LLMs) and other recent developments in foundational AI models in research workflows as well as to discuss the future of scientific research processes with this new technology present. \n\n\n\nWe will start the morning with inspirational talks about new advances in research workflow automation. During lunch\, there will be a possibility to network and discuss different perspectives with other attendees. After lunch we plan to have interactive sessions where the audience will have an opportunity to share and discuss visions and expectations\, including spontaneous flash/pop-up talks by the attendees. \n\n\n\nThe talks will be livestreamed through Zoom. The rest of the event is on-site in Biomedicum only. \n\n\n\nRegistration\n\n\n\nRegistration \n\n\n\nParticipation is free of charge on the first-come first-served basis. Refreshments and lunch will be served for the on-site participants. Unfortunately\, we cannot accommodate allergies or dietary preferences for those who register after March 1. If you register to listen to livestreamed talks on Zoom\, you will receive a link on the day of the event. The talks will not be recorded and saved\, only streamed live on the day. \n\n\n\nRegister to attend\n\n\n\nWaiting List \n\n\n\nTo avoid empty seats\, registration will remain open until the event begins. If we reach full capacity\, a waiting list will be activated. Sign up for the waiting list\, and you will automatically receive an email when a spot becomes available. You must accept to secure the spot. If you decline\, the offer will go to the next person on the waiting list. \n\n\n\nCancellation \n\n\n\nTo minimize empty seats and especially food waste\, you must cancel your registration if you are unable to attend the event. If a waiting list is activated\, your spot will go to someone else. Otherwise\, your cancellation will result in us covering the cost of your refreshments and lunch. \n\n\n\nIf you have questions\, please contact datacentre@scilifelab.se \n\n\n\n\n\n\n\n\n\n\n\nSpeakers\n\n\n\nOlli Kallioniemi (KI/FIMM) – AI-Empowered Life Science: How Can You Benefit Today and in the Future?\nNobel prizes\, huge tech investments\, generative AI and AI agents\, multidisciplinary expertise\, expectations on emerging superhuman intelligence\, and 1\,000+ AI-powered approved medical devices all highlight AI’s transformative potential for life scientists. Yet\, many researchers remain unaware or skeptical\, often due to limited exposure. This talk will cover AI’s current and future impact in life sciences\, highlighting how it can empower every scientist\, boost research productivity\, and foster innovative approaches. \n\n\n\nOlli Kallioniemi is the Founding Director of the SciLifeLab & Wallenberg Data-Driven Life Science (DDLS) Program and served as Director of SciLifeLab from 2015 to 2024. He is a Professor of Molecular Precision Medicine at Karolinska Institute (OnkPat) and holds a joint appointment at the Institute for Molecular Medicine Finland (FIMM) at the University of Helsinki. He has recently focused on exploring and explaining the opportunities that AI offers for life science research and how AI can benefit every researcher. \n\n\n\n\nMelissa Harrison (EMBL-EBI) – How Europe PMC uses and supports LLM development for research workflows\nEurope PubMed Central (Europe PMC)\, developed by EMBL-EBI\, is a free\, open-access literature database containing over 45 million life science literature outputs; over 10 million of which are full text. This includes almost a million preprints from 34 different servers. Associated research outputs\, such as data\, are linked to the literature\, which is also enriched with additional persistent identifiers\, text mined funding information\, and text mined annotations of the articles and supplementary files. Annotations are dictionary-based and are being transitioned to a machine learning approach. This talk will discuss the potential of this transition and will explore how Europe PMC plans to leverage machine learning in the future while maintaining the community’s trust in its curated\, open dataset as a reliable resource for scientific research. Words of caution about AI and ghost workers\, including biocurators\, will also be mentioned. \n\n\n\nMelissa Harrison is the Lead of Literature Services at EMBL’s European Bioinformatics Institute (EMBL-EBI). After completing a biology degree at King’s College London she worked in scientific publishing for two decades. In her previous role at eLife she honed her skills in open science policy and implementation and has been instrumental in the propagation of open persistent identifiers and metadata. \n\n\n\n\n Aasa Feragen (DTU) – AI fairness — it doesn’t have to be hard\nAasa Feragen is a Professor in Medical Image Analysis at the Technical University of Denmark (DTU). \n\n\n\n\nMartin Eklund (KI) – Limitations of foundation models for achieving optimal performance\nFoundation models are undoubtedly highly useful. But are they a panacea for advancing performance of deep learning systems? If not\, what are their limitations? In the presentation\, we explore these questions using large and rich digitized prostate pathology data as an example. \n\n\n\nMartin Eklund is professor of epidemiology at the Department of Medical Epidemiology and Biostatistics where he focusses his research on reducing the mortality of prostate cancer as well as the negative side effects of today’s imprecise diagnostics and treatment selection. He works a lot on development of AI systems for clinical decision making. \n\n\n\n\nPrashant Singh (UU) – AI and Optimization for Science: Principles and Pitfalls\nData-driven science has emerged as a modern pillar of science\, complementing theory\, experiments and computational approaches. Scientific workflows – from design of experiments to data analysis\, have greatly benefited from tools and techniques from various fields including optimization\, statistics\, computational science\, etc. In this talk\, we will motivate principled approaches for various stages of the scientific research pipeline\, from traditional foundations such as optimization\, to recent AI-based advances such as large-language models. \n\n\n\nPrashant is an Assistant Professor\, and a SciLifeLab fellow hosted at the Department of Information Technology\, Science for Life Laboratory\, Uppsala University. His research interests involve developing machine learning and optimization methods to enable fast\, data-efficient analysis and processing of scientific data\, particularly in the domain of life sciences. \n\n\n\n\nPhil Ewels (Seqera) – Building and testing scientific workflows with LLMs and AI agents\nNextflow has become the leading tool for scientific workflows in bioinformatics\, but writing workflows can be challenging. This talk introduces Seqera AI\, a new tool that helps generate Nextflow pipelines either from scratch\, from existing scripts\, or even other workflow languages. I’ll discuss how Seqera AI is able to generate best-practice DSL2 code that follows nf-core guidelines\, and how we go beyond just code generation: creating and running test suites with AI agents\, streamlining development while improving code quality and validation. \n\n\n\nPhil Ewels is Senior Product Manager for Open Source at Seqera\, working with Nextflow\, MultiQC\, nf-core and Wave. Before joining Seqera in 2022\, Phil worked at the National Genomics Infrastructure (NGI) at SciLifeLab in Stockholm\, Sweden. It was through this work that Phil became involved with Nextflow and eventually co-founded the nf-core community. Phil’s career has spanned many disciplines from lab work and bioinformatics research in epigenetics\, through to software development and community engagement. He is the author of MultiQC\, SRA-Explorer\, QCFail.com\, and has a PhD in Molecular Biology from the University of Cambridge\, UK. \n\n\n\n\nProgram\n\n\n\nAutomation_of_research_workflows_March_6_programmeDownload URL:https://www.scilifelab.se/event/automation/ LOCATION:Eva & Georg Klein lecture hall\, Biomedicum\, Solnavägen 9\, 171 65 Solna\, Solna\, 171 65\, Sweden CATEGORIES:Event ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2025/01/circos_cropped.png END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Stockholm:20250317T120000 DTEND;TZID=Europe/Stockholm:20250318T150000 DTSTAMP:20260502T080510 CREATED:20241204T083941Z LAST-MODIFIED:20250312T072352Z UID:10001415-1742212800-1742310000@www.scilifelab.se SUMMARY:Imaging in Cell and Molecular Biology DESCRIPTION:The DDLS research area symposia series aims to engage and build a strong national scientific community around the DDLS research themes. Each of the four areas arranges two symposia per year. Everyone interested in data-driven research is welcome to take part. We want to bring together researchers\, industry\, and healthcare to foster collaboration and push the frontiers of data-driven life science. \n\n\n\nThe DDLS research area Expert Group in Cell and Molecular Biology invites all interested in Data-driven life science to meet\, present\, interact\, and discuss Imaging in Cell and Molecular Biology. \n\n\n\nThe event will take place at Ångström Laboratory in Uppsala and will include presentations from international and national invited speakers and selected abstracts. The event is free of charge. \n\n\n\nDate: March 17 – 18\, 2025 \n\n\n\nStart: at 12:00 on March 17\, with lunch and registration. \n\n\n\nEnd: with lunch 12:20-13:15 on March 18. \n\n\n\nVenue: Room Heinz-Otto Kreiss\, Ångström Laboratory\, Lägerhyddsvägen 1\, 752 37 Uppsala. Find your way – Maze map link here! \n\n\n\nFind your way: From Uppsala Central Station\, take buss № 4 (place B4) to Polacksbacken (find timetables for Uppsala City buses here). \n\n\n\nPoster session\n\n\n\nThe poster session starts at 17:10 with networking and refreshments. Find the poster list and abstracts below. \n\n\n\nFor accepted Posters\, if you have registered for: \n\n\n\n\nPaper/canvas poster: Hang your poster during the coffee break in Room 101136 (Evelyn Sokolowski). \n\n\n\nDigital poster: Display your presentation in Room 101142 (next to Evelyn Sokolowski).\n\n\n\n\nPins will be available\, and the poster boards will be marked with poster numbers. \n\n\n\nList Posters Abstract v6Download\n\n\n\nCompany Exhibition\n\n\n\nYou will have the opportunity to meet with the following companies during the symposia: \n\n\n\n\nCarl Zeiss AB\n\n\n\nBioNordika AB\n\n\n\nTdB Labs AB\n\n\n\nMicromedic AB\n\n\n\nBruker Nordic AB\n\n\n\n10x Genomics Sweden\n\n\n\n\nCompany contact Erika Erkstam\, erika.erkstam@SciLifeLab.uu.se. \n\n\n\nIn compliance with GDPR regulations\, conference participants may not be added to company newsletters\, mailing lists\, or similar subscriptions without their explicit consent. \n\n\n\nRegistration\n\n\n\nThe registration deadline is March 3. To avoid empty seats\, registration will remain open until the event begins\, BUT registering after March 3 requires you to write your name on a name tag at the on-site registration. Unfortunately\, we cannot accommodate allergies or dietary preferences for those who register after March 3. \n\n\n\nMarch 4: The event has reached full capacity\, so a waiting list has been activated. If you sign up for the waiting list\, you will automatically receive an email when a spot becomes available. You must accept within 24 hours to secure the spot. If you decline\, the offer will go to the next person on the waiting list. \n\n\n\nRegistration\n\n\n\nCancellation\n\n\n\nTo minimize empty seats and food waste\, you must cancel your registration if you are unable to attend the symposia. Cancel via the Confirmation email or send an email to events@scilifelab.se. \n\n\n\n\n\n\n\nInvited speakers\n\n\n\nDownload the Speaker abstracts: \n\n\n\nDDLS CMB SpeakersDownload\n\n\n\nMarta Carroni\, SU\nTitle of talk: Structural basis for bacterial protein disaggregation and proteolysis  \n\n\n\nAbstract: Protein homeostasis is meticulously maintained across all cells\, spanning from archaea to humans. Any deviation from the equilibrium of the proteome\, induced by stress or cellular aging\, leads to the accumulation of misfolded proteins\, contributing to cellular toxicity. A complex proteostasis network actively manages misfolded proteins through processes such as refolding\, degradation\, or sequestration into intracellular inclusions. Integral to this protein quality control system are ATPases from the AAA+ superfamily (ATPases Associated to a variety of cellular Activities). \n\n\n\nThese AAA+ proteins\, universally present in organisms\, share a common structural fold for ATP hydrolysis\, but each possesses distinct function-specific domains\, enabling specialization in particular cellular activities and interactions with regulatory protein partners. \n\n\n\nOur work focuses on the structural investigation of bacterial Hsp100 AAA+ chaperones involved in protein quality control. We aim at understanding their fine-tuned regulation\, which is absolutely required by the bacterium to survive harsh environment conditions and useful for us in the effort of killing pathogenic bacterial strains. Using cryo-EM in combination with biochemical functional assays\, we can describe the molecular tuning mechanisms used by bacteria to assure the disaggregation or proteolysis of toxic protein species only\, while leaving intact functional protein molecules. \n\n\n\nBio: Marta Carroni is the Head of the Swedish National Cryo-EM Facility at SciLifeLab in Stockholm\, whose start and development she drove since its institution in 2016. She is a trained structural biologist and more specifically an expert in cryo electron microscopy (cryo-EM)\, technique on which she received extensive training since 2007 first at Imperial College London and then at Birkbeck College London\, under the supervision of Helen Saibil. Marta Carroni has initiated and trained in electron microscopy and image processing a large number of researchers in Sweden and abroad; she is often invited as teacher at cryoEM symposia and workshops. For this contribution\, she has been named one of the female innovators by the Italian Association of Women Inventors and Innovators in 2018 and awarded the Hugo Theorell price in 2023. Since 2020\, she is also the director of the Cellular and Molecular Imaging platform at SciLifeLab where she oversees the integration between different imaging modalities. Since 2022\, thanks to fundings form KAW\, SSF and support from Stockholm University\, she can run independent research projects with her group\, composed of 2 PhD students and 2 postdocs\, mainly looking at AAA+ molecular motors and their regulatory mechanisms in bacterial and human systems. The group often hosts master and Erasmus students and\, while developing an independent research path\, fosters many collaborations in Sweden and abroad.  \n\n\n\n\nJan Ellenberg\, Director SciLifeLab\nTitle of talk: Quantitative Imaging of Protein Networks and Genome Structure in Single Human Cells and an Outlook on Alpha Cell \n\n\n\nAbstract: The rapid development of new imaging technologies allows unprecedented insights into the molecular machinery inside living cells and organisms. For the first time\, light and electron microscopy have molecular sensitivity and resolving power in situ\, and\, if used together\, can connect structural detail with molecular dynamics of the whole cell. Aided by machine learning driven image analysis powered by open sharing of image data\, this provides unprecedented opportunities for new insights into the molecular mechanisms that drive life’s core functions at the scale of the cell. \n\n\n\nI will present the progress we have made to study one of life’s most fundamental functions\, cell division\, by mapping the dynamic protein network\, assembly of individual protein complexes and genome re-folding that drive it. Our work has studied cell division in human cancer cells and early mammalian embryos using advanced cross-scale imaging methods\, including light-sheet\, quantitative fluorescence correlation spectroscopy (FCS)-calibrated\, super-resolution and correlative light and electron microscopy. The quantitative integrated molecular data that these new technologies deliver\, allow us to better understand how the molecular machinery functions in space and time to ensure faithful cell division and prevent the errors that underlie congenital disease\, infertility and cancer. \n\n\n\nBio: Since July 2024\, Professor Ellenberg is appointed Director of SciLifeLab. Jan Ellenberg is distinguished for many contributions to the cell biology and imaging field. The majority of these were made at the European Molecular Biology Laboratory (EMBL) where he is Senior Scientist and Head of the Cell Biology and Biophysics Unit. His major research contributions cover several aspects of the cell division cycle and nuclear organization\, including systematic analysis of mitosis\, nuclear pore complex structure and assembly\, as well as chromatin organization and formation and segregation of mitotic and meiotic chromosomes.His goal has been to obtain structural and functional measures of the required molecular machinery inside cells using quantitative 4D imaging\, single molecule spectroscopy\, as well as light sheet and super-resolution microscopy\, which his group is constantly developing and automating to address all molecular components comprehensively. \n\n\n\n\nAnja Hauser\, DRFZ\, Germany\nTitle of talk: Functional\, multidimensional optical microscopy to analyze the function of myeloid cells during bone regeneration \n\n\n\nAbstract: Focusing on bone regeneration after injury\, we aim to understand how the tissue microenvironment affects the metabolism of myeloid cells in the bone marrow over time\, and how that impacts on cell function. We previously demonstrated that CX3CR1+ myeloid cells act as trailblazers for osteogenic type H vessels in the bone marrow. In order to analyze this process in 3D\, we developed a tissue clearing\, staining and light sheet fluorescence microscopy imaging pipeline called MarShie\, optimized to image the entire intact femur at subcellular resolution down to the deepest bone marrow regions. To analyze the three-dimensional dataset\, we applied a machine learning approach\, enabling us to segment thousands of cells. We find that during homeostasis CX3CR1+ myeloid cells localize in perivascular niches\, whereas CD169+ myeloid cells are dispersed in the parenchyma. After injury\, CX3CR1+ myeloid cells relocate and sequester the injury site prior to vascularization. Analysis of the femur after full osteotomy reveals that vessel sprouting is initiated at periosteal regions.Phenotypes and functions of immune cells are tightly linked to their metabolic profiles\, which in turn is affected by changes in the tissue microenvironment. We developed a lens implant for longitudinal intravital imaging of the mouse femur\, to enable micro-endoscopic fluorescence lifetime imaging (FLIM) for metabolic profiling at the same tissue region over the whole time course of bone healing. Using a reference system of fluorescence lifetimes derived from the ubiquitous metabolic co-enzymes NADH and NADPH (NAD(P)H)\, we can determine enzymatic activities in vivo. This approach allows us to identify a high degree of dynamics in dominant metabolic pathways for energy production. Additionally\, we distinguish pathways associated to cellular function and cellular state\, i.e. oxidative burst (NADPH oxidase activity) and dormancy or death. Under in vivo conditions\, myeloid cells with various metabolic profiles\, i.e. using other pathways for energy production than the anaerobic pathway associated with pro-inflammatory cells\, perform the oxidative burst necessary for phagocytosis. This demonstrates that a high metabolic flexibility of myeloid cells in vivo. \n\n\n\nBio: Anja Hauser holds the Professorship for Immune Dynamics at Charité – Universitätsmedizin Berlin\, and is head of Program Area “Cell and Tissue Immunology” at Deutsches Rheuma-Forschungszentrum Berlin\, Germany.Anja is a trained veterinarian who received her degree at the Tierärztliche Hochschule Hannover\, Germany. During her PhD thesis\, she investigated microenvironmental conditions that promote plasma cell longevity in tissues and became interested in the spatial organization of immune cells. Her postdoctoral work at Yale University School of Medicine focused on the dynamics of germinal center B cells\, which she analyzed by intravital microscopy. Since founding her own laboratory\, she has broadened her focus from the analysis of B cells to other adaptive and innate immune cells\, with a particular focus on the analysis of immune-stroma interactions and the signals that maintain chronic inflammation.Thus\, her work is centered around the basic concept that the immune system is organized in a spatial and temporal manner. To that end\, she develops and applies advanced imaging technologies. Anja is founding member of the European Society for Spatial Biology. \n\n\n\n \n\n\n\n \n\n\n\n\nSverker Holmgren\, Data Science Node\, Chalmers\nTitle of talk: National Data Services for Imaging in Cell and Molecular Biology \n\n\n\nAbstract: The Gothenburg DDLS Data Science Node is developing and deploying national services for managing and analyzing images in CMB. The node works together with the SciLifeLab Data Center\, and the areas covered are selected jointly with the DDLS Expert Group in CMB. Currently\, a national Open Microscopy Environment service (OMERO) for image data management and storage is being deployed\, and this will be connected to High Performance Computing resources for analysis\, using e.g. AI models\, and later also to image repositories for preservation and open sharing. In the next phase\, the underlying work setting up this national service is used to develop and deploy two other sets of prioritized services. \n\n\n\nBio: Sverker Holmgren is the Director of Chalmers e-Commons at Chalmers University of Technology\, where he is also a Professor of Scientific Computing. Chalmers e-Commons is Chalmers’ digital infrastructure for research\, providing integrated support to Chalmers researchers with a focus on data management\, analysis\, and data publication. Together with Chalmers Facility for Computational Systems Biology\, Chalmers e-Commons hosts the Gothenburg DDLS Data Science Node in Cell and Molecular Biology. Chalmers e-Commons is also the Chalmers node in other selected national and international digital infrastructures and initiatives\, e.g. the National Academic Infrastructure for Supercomputing (NAISS)\, the Swedish National Data Service (SND)\, and the National Research Infrastructure for Data Visualization (InfraVis). \n\n\n\nHolmgren has a long history of engaging in data and large-scale computing infrastructures locally\, nationally\, and internationally. Besides leading the local effort at Chalmers\, he is a member of national and international reference groups and initiatives on data management. Holmgren is a permanent Expert in the Swedish Delegation to the European Strategic Forum for Research Infrastructure (ESFRI)\, a member of the ESFRI IG\, and a Swedish Delegate in the European e-Infrastructure Reflections Group (e-IRG). Earlier\, Holmgren held a professorship at Uppsala University where he also served as the Dean of Mathematics and Computer Science for six years. \n\n\n\n\nRasmus Krogh Norrild\, DTU\, Denmark\nTitle of talk: High-throughput experimental approaches for quantifying the thermodynamics of biomolecular condensate formation \n\n\n\nAbstract: Biomolecular condensates (BMCs) are phase-separated and membraneless compartments enriched in specific biomolecules\, playing key roles in biological function and disease. Understanding how BMC formation depends on solution conditions\, amino acid sequence\, and nucleotide sequence is crucial\, particularly for applications in drug discovery. High-throughput methods are therefore highly valuable for large-scale screening and for elucidating the fundamental driving forces of condensate formation. In this seminar\, I will present Condensate Partitioning by mRNA-Display (CPmD)\, a novel high-throughput approach based on mRNA display (Norrild et al.\, bioRxiv 2024). CPmD enables the simultaneous analysis of partitioning behaviour for tens of thousands of peptides and their corresponding synthetic mRNAs within BMCs\, offering new insights into the thermodynamics of condensate formation. To validate CPmD\, we employed two microfluidics-based methods\, Capflex (Stender\, Ray\, Norrild et al.\, Nat. Commun. 2021) and TDIPS (Norrild et al.\, Angew. Chem. Int. Ed. 2024)\, both leveraging the commercially available FIDA1 microcapillary system. These methods demonstrate how proteome-scale CPmD data on peptide partitioning can directly inform on biomolecular condensate formation of the proteins from which the peptides originate. \n\n\n\nBio: I am a postdoctoral researcher at the Technical University of Denmark (DTU)\, specializing in protein biophysics. I have a MSc in Biochemistry from the University of Copenhagen and I did my PhD in Biophysics at DTU on Biophysics. My research focuses on understanding how protein structure\, stability\, and phase behavior contribute to cellular function and disease. I combine experimental and data-driven computational approaches to study and engineer dynamic proteins\, especially intrinsically disordered regions of these. My goal is to integrate quantitative biophysics with cell biology to uncover new insights into protein function in complex biological systems. \n\n\n\n\nWei Ouyang\, DDLS Fellow\, KTH\nTitle of talk: Unleash the Power of Generative AI for Data-Driven Cell Biology \n\n\n\nAbstract: This talk presents the ongoing work of AICell Lab (https://aicell.io) focusing on developing generative AI\, diffusion models for human cell modeling\, and AI-driven automation in microscopy and robotics. We focus on the development of the REEF Microscopy Imaging Farm\, which aims to create fully automated imaging systems that generate high-quality datasets for cell simulation. We are also building scalable platforms like ImJoy and Hypha\, which power the BioImage Model Zoo—a community-driven repository enabling easy AI model testing. Additionally\, our BioImage Chatbot\, an AI agent built on a bioimaging knowledge base\, is being extended for automated scientific discovery. These efforts converge in the Hypha platform\, connecting hardware\, AI models\, and users to advance whole-cell modeling and redefine in-silico research and drug discovery. \n\n\n\n\nErdinc Sezgin\, KI\nTitle of talk: Physical properties of cells and nanoscale bioparticles as new biomarkers of health and disease \n\n\n\nAbstract: Remodelling of our cells as response to environmental changes is essential for their survival and function. Although numerous studies aimed at finding protein markers during such cellular processes\, there is a major gap in our understanding of how collective biophysical properties of the cells (such as stiffness\, membrane fluidity\, viscosity etc) alter during these crucial biological processes. Similarly\, our understanding of how biophysical properties of cells change in diseases is also limited. To gain a thorough mechanistic perception of cellular processes and diseases\, it is essential to fill this gap and have a clear and quantitative picture of biophysical remodelling of the cells.We and others have made extensive effort to unravel the biophysical aspects of cells in a quantitative manner. To achieve this\, we developed advanced imaging approaches that could reveal the molecular details with very high spatiotemporal resolution. These technologies allowed us to see how biophysical properties of cells play crucial roles for signalling from molecular to cellular level. Although these technologies were extremely useful to study biophysical aspects of cellular life at the molecular level\, their low sampling (one cell at a time) has been a major obstacle to apply them to medical problems that require measuring thousands of cells. This can be overcome with high throughput methodologies that can robustly report on the ensemble biophysical properties of cells which require reliable reporters and instruments. Thus\, while developing advanced instrumentation\, we also develop reliable probes to quantify different biophysical properties of cells. Here\, I will discuss our approach from probe development to high throughput biophysical analysis \n\n\n\nBio: Erdinc Sezgin studied Genetics and Bioengineering at the Yeditepe University\, Istanbul Turkey. He next joined International Max Planck Research School for PhD in Dresden\, Germany. After graduation\, he obtained EMBO\, Marie Curie and Newton fellowships to perform his postdoctoral research in immunology and imaging at University of Oxford. Since 2020\, he has been leading his independent lab as an Associate Professor at Karolinska Institutet and SciLifeLab. He is currently an EMBO Young Investigator and a Visiting Faculty at University of Oxford. \n\n\n\n\nEduardo Villablanca\, KI\nTitle of talk: Unraveling the Molecular Architecture of the Intestinal Barrier: Insights from Spatial Transcriptomics \n\n\n\nAbstract: The complex cellular network that constitutes the intestinal barrier is crucial for maintaining health and preventing diseases. In this talk\, I will present the remarkable capabilities of spatial transcriptomics (ST) in unveiling the molecular organization of the entire colonic tissue during mucosal healing and tumorigenesis. By leveraging ST\, we revealed a previously undiscovered regionalization of the colon’s transcriptomic landscape under steady state conditions\, which undergoes dramatic changes during mucosal healing. We identified spatially organized transcriptional programs that define compartmentalized mucosal healing\, including regions exhibiting dominant wired pathways. Furthermore\, I will discuss the translational potential of our findings by mapping transcriptomic modules associated with human diseases. \n\n\n\nBio: Dr. Villablanca is a developmental biologist turned immunologist with expertise in cell migration and mucosal immunology. He began his research using zebrafish as an in vivo model before shifting his focus to immunology during his PhD in Molecular Medicine at San Raffaele University in Milan\, Italy. His interest in intestinal leukocyte trafficking led him to Harvard Medical School\, where he trained as a postdoctoral fellow in Dr. Rodrigo Mora’s lab. After four years\, he was promoted to Instructor in Medicine and joined Dr. Xavier’s lab to study inflammatory bowel disease (IBD) risk genes and their role in intestinal immune homeostasis.In late 2014\, Dr. Villablanca was recruited to establish his own laboratory at the Karolinska Institute’s Division of Immunology and Respiratory Medicine in Sweden. Now a Professor of Gastrointestinal Immunology\, Wallenberg Fellow\, and ERC awardee\, he leads a research team integrating developmental biology\, mucosal immunology\, and systems biology to uncover how intestinal homeostasis is maintained and how its disruption contributes to disease.Visit the Villablanca lab webpage here or watch the research video summary here.BsKy: @ejvillablanca.bsky.social \n\n\n\n\nFor questions about the Program\, please contact the Scientific Committee: \n\n\n\n\nIda-Maria Sintorn\, UU\n\n\n\nMarc Friedländer\, SU\n\n\n\n\nAbout the event\, please contact Project leader: Erika Erkstam\, Operations office\, SciLifeLab \n\n\n\nProgram\n\n\n\nDDLS-Symposium-PROGRAM-NY2Download\n\n\n\nMore information about the Data-driven Life Science Research area\n\n\n\n\n\n\n\nDDLS Cell and Molecular Biology URL:https://www.scilifelab.se/event/imaging-in-cell-and-molecular-biology/ LOCATION:Ångström Laboratory\, Lägerhyddsvägen 1\, Uppsala\, Sweden CATEGORIES:Event ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2023/03/CMB_web.png END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Stockholm:20250318T150000 DTEND;TZID=Europe/Stockholm:20250321T140000 DTSTAMP:20260502T080510 CREATED:20250109T082032Z LAST-MODIFIED:20250318T173404Z UID:10001427-1742310000-1742565600@www.scilifelab.se SUMMARY:DDLS Research School Annual Meeting DESCRIPTION:The first DDLS Research School Annual Meeting for PhDs and PIs\, including DDLS fellows. This meeting is by invitation only. DDLS PhD students are invited to participate the entire duration of the meeting (18-21 March)\, while their supervisors are invited to participate 18-19 March (afternoon-to-lunch) \n\n\n\n \n\n\n\nProgram\n\n\n\nTuesday March 18: \n\n\n\n14:30-15:30Registration and coffeeLilla Kongressen15:30-16:30Welcome and introduction to the DDLS Research SchoolLilla Kongressen16:30-17:15– PIs: meeting with DDLS Research School Directors                               – PhD students: group activity– Room 7E – Lilla Kongressen17:30-18:3017:30-19:00– PIs: questions and answers with DDLS RS Directors – PhD students: Social activity – Lilla Kongressen– House 9\, Stora Kongressen19:00Welcome drinkLobby\, main building19:30DinnerRestaurant\, main building\n\n\n\n\n\n\n\nWednesday March 19:  \n\n\n\n07:00   Breakfast opens08:30-10:10PI presentations: CMB & EBI Stora Kongressen10:10-10:40Coffee with Group PhotoStora Kongressen10:40-12:30PI presentations: EB & PMD Stora Kongressen12:45– Lunch – Set up your poster in Stora KongressenMain building13:45Bus departure for PIs Outside main building14:00-16:30 Workshop led by Maja Neiman\, SwedenBioStora Kongressen16:30-18:30Poster session with refreshmentsStora Kongressen19:00  Dinner Restaurant\, main building\n\n\n\n\n\n\n\nThursday March 20:     \n\n\n\n08:30-17:00Course: Open science in the Swedish contextLilla Kongressen11:30LunchRestaurant\, main building17:00-18:30Free time18:30 Dinner Restaurant\, main building20:00 Music quiz House 9\, Bar\n\n\n\n\n\n\n\nFriday March 21:    \n\n\n\n09:00-10:00Introduction to upcoming DDLS Research School coursesLilla Kongressen10:00-10:30CoffeeLilla Kongressen10:30-11:30Group work: future courses in the DDLS Research SchoolLilla Kongressen11:30-12:00Summary of the Annual Meeting [RS directors]Lilla Kongressen12:00 Lunch. Annual Meeting ends.Restaurant\, main building13:15 Bus departureOutside main building\n\n\n\n\n\n\n\nBustransfer\n\n\n\nDetails regarding bus transfer will be sent by email to those who have signed up for bus in their registration \n\n\n\n18 March Bus from Uppsala at 13:15from Stockholm at 13:00 \n\n\n\n19 March From Djurönäset to Stockholm and Uppsala 13:45 \n\n\n\n21 March From Djurönäset to Stockholm and Uppsala 13:15 URL:https://www.scilifelab.se/event/ddls-research-school-annual-meeting/ LOCATION:Djurönäset\, Seregårdsvägen 1\, Djurhamn CATEGORIES:Community END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Stockholm:20250425T100000 DTEND;TZID=Europe/Stockholm:20250425T110000 DTSTAMP:20260502T080510 CREATED:20250403T100003Z LAST-MODIFIED:20250403T100224Z UID:10001522-1745575200-1745578800@www.scilifelab.se SUMMARY:Towards an interpretable deep learning model of cancer cells. DESCRIPTION:Avlant Nilsson\, DDLS fellow\, Karolinska Institutet \n\n\n\nNBIS and SciLifeLab Data Centre arrange an open SciLifeLab AI Seminar Series aimed at knowledge-sharing about Artificial Intelligence and applications in the Life Science community. The seminar series is open to everyone. The seminar is run over Zoom on the third Friday of the month during academic terms\, typically between 10 and 11 am\, with approx. 45 min presentation and 15 min discussion. \n\n\n\nAbstract \n\n\n\nCancer emerges from complex molecular interactions that drive pathological cells states. To model these interactions\, we develop deep learning frameworks of cellular signaling\, gene regulation\, and metabolism. Our approach embeds prior knowledge networks into a recurrent architecture\, allowing us to capture cellular dynamics by training on omics data across different perturbations and conditions.At the core of our modeling is a propagator function that predicts the next cell state based on the current state\, enabling the simulation of molecular state transitions over time. To ensure biological plausibility\, we employ a technic based on feature embedding and superposition that encodes molecular identities in a structured feature space while restricting the predictive input for each molecular state to its direct network connections. These structured embeddings facilitate the use of a universal function allowing generalization across different molecules\, cell types\, and experimental settings.By constraining learned representations to known molecular entities\, our framework maintains interpretability while enabling data-driven inference. Ultimately\, we aim to integrate our models into a unified representation of cellular behavior. Bridging mechanistic understanding with predictive modeling\, this work lays the foundation for AI-driven precision medicine\, offering new tools to simulate and control cancer cell states. URL:https://www.scilifelab.se/event/towards-an-interpretable-deep-learning-model-of-cancer-cells/ LOCATION:Online event via Zoom CATEGORIES:Event END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Stockholm:20250429T150000 DTEND;TZID=Europe/Stockholm:20250429T160000 DTSTAMP:20260502T080510 CREATED:20250409T152618Z LAST-MODIFIED:20250409T152810Z UID:10001526-1745938800-1745942400@www.scilifelab.se SUMMARY:Unlocking Innovation: Best Practices for Corporate-Academic Partnerships DESCRIPTION:SwedenBIO’s IP Task force is inviting you to an engaging seminar on how to level up your academic collaborations. We will present our Term Sheet Checklist\, a tool designed to simplify and secure successful agreements between industry and academia in the Life Science sector. You’ll also get an exclusive look at the Data Driven Life Science (DDLS) program\, showcasing their unique training and research opportunities for industry PhD students. \n\n\n\nKey Topics: \n\n\n\nIntroduction of the Data Driven Life Science program (DDLS) \n\n\n\nUnlocking Innovation and collaboration \n\n\n\nLaunch of Term Sheet Checklist \n\n\n\nVenue\n\n\n\nStockholmCirio Advokatbyrå AB\, Biblioteksgatan 9View mapGothenburgGoCo Health Innovation City\, Entreprenörsstråket 10View mapJoin OnlineYou will get an invitation when the event is close \n\n\n\nRead more and Register here URL:https://www.scilifelab.se/event/unlocking-innovation/ CATEGORIES:Event END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Stockholm:20250505T120000 DTEND;TZID=Europe/Stockholm:20250506T130000 DTSTAMP:20260502T080510 CREATED:20241220T130709Z LAST-MODIFIED:20250504T184509Z UID:10001423-1746446400-1746536400@www.scilifelab.se SUMMARY:Infectious disease epidemiology: surveillance\, forecasting and modelling DESCRIPTION:Join the Data-driven Epidemiology and Biology of Infection research area for an inspiring Lunch-to-lunch meeting filled with science\, networking\, and discussions. \n\n\n\nThis event is arranged by the Data-driven Life Science program (DDLS)\, hosted by SciLifeLab and Knut and Alice Wallenberg Foundation. \n\n\n\nThe DDLS research area symposia series aims to engage and build a strong national scientific community around the DDLS research themes. Each of the four areas arranges two symposia per year. Everyone interested in data-driven research is welcome to take part. We want to bring together researchers\, industry\, and healthcare to foster collaboration and push the frontiers of data-driven life science. \n\n\n\nDate: May 5 – 6\, 2025 \n\n\n\nTime: Lunch to Lunch \n\n\n\nVenue: PÄRLAN – Albano – Hus 1 / Plan 6\, See map. \n\n\n\n \n\n\n\nRegistration\n\n\n\nThe event has reached full capacity. \n\n\n\n\n\n\n\nProgram\n\n\n\nDDLS EBI program_May 2025_v3Download\n\n\n\nPractical information\n\n\n\nDirections: Albano is between the main campus of Frescati and Roslagstull. You can either walk from T: Tekniska högskolan (exit Körsbärsvägen) or T: Universitet. By bus you can either take bus 50 from T-Odenplan (direction Universitetet) or from T-Universitetet (direction Odenplan) and get off at Albano. It is easiest to enter the buildings from the main road Roslagsvägen – then you are on level 2. \n\n\n\nStart: at 12:00 with Lunch or 13:00 in the Lecture hall on May 5. \n\n\n\nRegistration: We’ll begin with Registration (from 11:45) and Lunch\, 12:00-12:45 at Restaurant Proviant Albano located in House 2 on Level 4. You need to register with your name or QR code (sent by email on May 5) at the SciLifeLab table outside the Restaurant to get a lunch coupon and a name badge before eating lunch. The Lecture hall is a short walk from the lunch restaurant. \n\n\n\nPlease be seated in Pärlan at 13:00 to start the Symposium. If you do not attend lunch\, you can register and get your name badge in the Lecture room. \n\n\n\nLecture hall: Pärlan. Located on floor 6 in House 1. \n\n\n\nImportant: The room is only accessible by elevator. Be sure to find the correct elevator\, which is located deep inside the building\, heading towards House 2. The code to the door and the elevator will be written on your name badge and communicated in the Welcome emails. \n\n\n\n \n\n\n\nmap_albanoDownload\n\n\n\nOrganizing committee:\n\n\n\n\nTom Britton\, Stockholm University\n\n\n\nStefan Engblom\, Uppsala University\n\n\n\nLaura Carroll\, Umeå University\n\n\n\nTove Fall\, Uppsala University\n\n\n\n\nQuestions can be answered by the Organizing Committee or events@scilifelab.se \n\n\n\nRead more about the Research area URL:https://www.scilifelab.se/event/ddls-ebi-symposium/ LOCATION:PÄRLAN – Albano – Hus 1 / Plan 6\, Roslagsvägen 26\, Stockholm\, 114 19 CATEGORIES:Event ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2023/03/EBI_web.png END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Stockholm:20250520T080000 DTEND;TZID=Europe/Stockholm:20250521T170000 DTSTAMP:20260502T080510 CREATED:20250414T144013Z LAST-MODIFIED:20250520T071639Z UID:10001501-1747728000-1747846800@www.scilifelab.se SUMMARY:Data Management in Life Science DESCRIPTION:Navigate Repositories\, GDPR\, and Support Networks with Confidence\n\n\n\nDiscover how to effectively manage\, share\, and safeguard your research data through practical guidance from both local and national experts. Engage in discussions on best practices grounded in the FAIR principles and Open Science. \n\n\n\nThis event is co-organized by the SciLifeLab Data Centre\, NBIS\, SciLifeLab Gothenburg\, the Swedish National Data Service (SND)\, and local support teams at the University of Gothenburg and Chalmers. \n\n\n\nWe warmly welcome life science researchers at all career stages—from master’s students to principal investigators—as well as data stewards\, technical staff\, and infrastructure experts based in Gothenburg. \n\n\n\nProgram\n\n\n\nMay 20 – Europa\, Conference Centre Wallenberg\, Medicinaregatan 20A \n\n\n\n10:00 – 10:30 “Fika” and registration \n\n\n\n10:30-12:00 Good Data Management Practices – available services and support\nGood data management practices are essential to increase the scientific and societal impact of your research. By adhering to the Open Science principles\, and by making your research more FAIR – findable\, accessible\, interoperable\, and reusable – you will increase the value of your research work. Doing this is easier than you might think\, and there is a lot of research support available to guide you. \n\n\n\nDuring this presentation you will get to know more about the different research support groups in Gothenburg (University of Gothenburg\, and Chalmers University)\, and the national research support groups (SciLifeLab Data Centre\, NBIS\, and SND)\, who are available to help you during all phases of your research project. \n\n\n\nThis Open Lecture is for everyone working in academia or healthcare\, who works with handling research data or would like to know more about this topic. \n\n\n\n\n12:00 – 17:00 The DDLS Precision Medicine Diagnostics (PMD) Minisymposium 2025 \nPioneering Data-Driven Precision Medicine and Diagnostics\, will take place at the same venue immediately following the Data Management Seminar. We warmly encourage you to take the opportunity to attend both events! \n\n\n\n\nMay 20 – Birgit Thilander\, Academicum\, Medicinaregatan 3 \n\n\n\n13:00 – 16:00 Network Event – Connecting Service Providers\nIf you want to join\, please reach out to us at gothenburg@scilifelab.se. \n\n\n\n\n\n\n\n\nMay 21 – Birgit Thilander\, Academicum\, Medicinaregatan 3 \n\n\n\n9:00-10:00 FAIR breakfast; An open forum for PhD students\, Postdocs and Master Students\n\n\nHere\, young scientists gather for breakfast and discussions on FAIR principles and best practices for research data management. \n\n\n\nFAIR stands for Findable\, Accessible\, Interoperable\, and Reusable — key principles that ensure data is well-organized and reusable. Understanding and applying good data management from the start of a project is not only a requirement for many funders and journals\, but also a valuable asset for researchers throughout their projects and beyond. \n\n\n\n\n\n\n\n\n\n\n\n\n10:15-12:00 Workshop 1 – Data submission to public repositories. \n\n\nBring your laptop! \n\n\n\nMaking the data underlying your research accessible to others—whether openly or with restrictions—is a fundamental part of a FAIR research process. When data are properly described and shared via a trusted data repository\, they can be re-used by you and others\, enabling collaboration and ensuring transparency and long-term preservation. Research data repositories allow data to be shared as open as possible\, as restricted as necessary\, fulfilling FAIR while meeting legal\, ethical\, or contractual requirements. \n\n\n\nThis workshop will give you the why\, where and how of data sharing via repository submission\, including a hands-on exercise. No prior knowledge is required in order to attend this workshop. \n\n\n\nLearning outcomes: \n\n\n\n\nKnow the benefits of data sharing\n\n\n\nKnow how to find a suitable repository for different types of data\n\n\n\nHave experience of a repository submission\n\n\n\n\n\n\n\n\n\n\n\n\n\n13:15-15:00 Workshop 2 – GDPR for life science research\nBring your laptop! \n\n\n\n\n\nThe General Data Protection Regulation (GDPR) must be followed whenever personal data is processed. This workshop will introduce the fundamental concepts in the regulation and discuss what impact the regulation has on day-to-day research activities in the life sciences. \n\n\n\nLearning outcomes: \n\n\n\n\nHave a basic understanding of what GDPR is and what the purposes the regulation has\n\n\n\nHave a basic understanding of central concepts in GDPR (for example personal data\, special category (“sensitive”) data\, data processing\, data subject\, data controller\, data processor\, lawful grounds and data protection principles)\n\n\n\nUnderstand how GDPR is relevant to life science research (including for example how to prevent re-identification)\n\n\n\nProvide some examples of best practices for how to comply with GDPR\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\nRegistration\n\n\n\n\nLate registrations are still possible\, but we cannot guarantee meals for those registering after May 15\, 2025. URL:https://www.scilifelab.se/event/data-management-in-life-science-2/ LOCATION:Birgit Thilander Lecture Hall\, Medicinaregatan 3\, Göteborg CATEGORIES:Event ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2021/03/data_life_cycle_9.png ORGANIZER;CN="SciLifeLab Gothenburg":MAILTO:gothenburg@scilifelab.se END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Stockholm:20250520T120000 DTEND;TZID=Europe/Stockholm:20250520T170000 DTSTAMP:20260502T080510 CREATED:20250221T095041Z LAST-MODIFIED:20250514T144157Z UID:10001493-1747742400-1747760400@www.scilifelab.se SUMMARY:Pioneering Data-Driven Precision Medicine and Diagnostics DESCRIPTION:DDLS Precision Medicine Diagnostics (PMD) Minisymposium 2025 \n\n\n\nWe are delighted to invite doctoral students\, postdoctoral researchers\, clinicians\, and professionals at all career stages to the DDLS PMD Minisymposium 2025 – an interdisciplinary event designed to showcase cutting-edge research and foster collaborative innovation in precision medicine and diagnostics. Join us in Gothenburg for an engaging and insightful experience. \n\n\n\nEvent Details: \n\n\n\nDate: May 20\, 2025 \n\n\n\nLocation: Hall Europa\, Wallenberg Conference Center\, Gothenburg \n\n\n\nCapacity: 100 participants \n\n\n\nAt this exclusive minisymposium\, you will have the opportunity to: \n\n\n\n\nEngage with Fellow Researchers: Hear from experts in data-driven life science and precision medicine through keynote presentations and visionary talks.\n\n\n\nParticipate in Interactive Sessions: Contribute to dynamic panel discussions addressing current challenges and future directions\, and experience rapid-fire talks by early-career researchers and postdoctoral fellows.\n\n\n\nShowcase and Discover Innovations: Explore groundbreaking research at our poster session that bridges the gap between clinical practice and translational science.\n\n\n\nNetwork and Collaborate: Connect with peers\, senior researchers\, and clinical experts to foster collaborative projects and exchange innovative ideas.\n\n\n\n\nThis event is tailored for professionals passionate about advancing precision medicine and diagnostics through data integration and interdisciplinary research. Whether you are leading groundbreaking projects or embarking on your scientific journey\, the DDLS PMD Minisymposium offers a platform to inspire\, innovate\, and shape the future of healthcare. \n\n\n\nRegister now to secure your place and join us in exploring new horizons in precision medicine and diagnostics. \n\n\n\nCollaboration and outreach flash talks \n\n\n\n2 min\, 1-2 slides max.\, do not present your research\, but present your needs or offers (are you looking for -or- can offer a specific kind of data or expertise\, are you looking for a tool to solve a specific -or- can you offer a tool to others and are looking for testers or users) \n\n\n\nRegistration\n\n\n\nSpeakers\n\n\n\n\nPaulo Czarnewski\, Precisium AI\n\n\n\nSara Hansson\, AstraZeneca\n\n\n\nLars Klareskog\, Senior Professor of Rheumatology\, Karolinska Institutet\n\n\n\nKimmo Kartasalo\, Assistant Professor\, DDLS Fellow\, Karolinska Institutet\n\n\n\nAntonio Lentini\, Assistant Professor\, DDLS Fellow\, Linköping University\n\n\n\nAbhishek Niroula\, Assistant Professor\, DDLS Fellow\, University of Gothenburg\n\n\n\nRichard Rosenquist Brandell\, Genomic Medicine Sweden\, Karolinska Institutet\n\n\n\n\nProgram\n\n\n\n12:00Registration & Poster set-upWallenberg Conference Center\, Gothenburg12:10Lunch Served in the restaurant Norden on the second floor13:00Scientific presentationsModerators: Annika Polster\, Qiaoli WangWelcome and Introduction to Precision Medicine and Diagnostics Research AreaJanne Lehtiö\, SciLifeLab/Karolinska Institutet13:10Use of Sweden’s national quality of care registers and affiliated biobanks for  large scale data-driven Precision Medicine researchLars Klareskog\, Karolinska Institutet13:35Identifying new markers of CH and predicting risk of hematologic malignanciesAbhishek Niroula\, SciLifeLab/University of Gothenburg13:50Foundation Models – A Panacea for Artificial Intelligence in Pathology?Kimmo Kartasalo\, SciLifeLab/Karolinska Institutet14:05Flash TalksModerators: Marcel Tabier and Muhammad Arif14:25Coffee Break with Matchmaking & Poster session15:10Scientific presentationsModerators: Avlant Nilsson\, Fulya Taylan15:10Harnessing atlas-level data for precision medicine applicationsPaulo Czarnewski\, Precisium AI15:35Transcriptional regulation of aneuploidyAntonio Lentini\, SciLifeLab/Linköping University16:00Implementing Precision Medicine in Drug DevelopmentSara Hansson\, Astra Zeneca16:30Precision Omics Initiative Sweden (PROMISE) – the design phaseRichard Rosenquist Brandell\, Genomic Medicine Sweden/Karolinska Institutet16:55Wrap-upJanne Lehtiö\, SciLifeLab/Karolinska Institutet URL:https://www.scilifelab.se/event/pioneering-data-driven-precision-medicine-and-diagnostics/ LOCATION:Europasalen\, Konferenscentrum Wallenberg\, Gothenburg\, Medicinaregatan 20\, Göteborg\, 413 90\, Sweden CATEGORIES:Event ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2025/03/PM4_BG.png END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Stockholm:20250526T090000 DTEND;TZID=Europe/Stockholm:20250526T170000 DTSTAMP:20260502T080510 CREATED:20250507T092724Z LAST-MODIFIED:20250523T065343Z UID:10001540-1748250000-1748278800@www.scilifelab.se SUMMARY:SciLifeLab Uppsala Spring Mini-Symposium DESCRIPTION:We’re thrilled to invite you to our first-ever SciLifeLab and DDLS Fellow/Alumni organized SciLifeLab Uppsala Spring Mini-Symposium in Navet\, BMC\, on the 26th of May. A full day dedicated to inspiring scientific talks\, meaningful interactions\, and collaborative discussions. \n\n\n\nJoin us as we explore how shared science can help strengthen connections across departments and universities. (Spots are limited to 90p.) \n\n\n\nPhD students and postdocs are especially encouraged to attend – it’s an excellent opportunity to expand your network and spark future collaborations! \n\n\n\nPhD/Postdoc\, you are welcome to present a poster. Reusing a recent poster is OK! \n\n\n\n \n\n\n\nWelcome! \n\n\n\nThe organizing team \n\n\n\nWojciech Michno\, Luisa Hugerth and Marcel Tarbier \n\n\n\nRegistration\n\n\n\nSchedule SciLifeLab Uppsala Spring Mini-Symposium v2Download URL:https://www.scilifelab.se/event/scilifelab-uppsala-spring-mini-symposium/ LOCATION:Navet\, SciLifeLab Uppsala\, SciLifeLab Uppsala\, BMC C11\, Husargatan 3\, Uppsala\, 75237\, Sweden CATEGORIES:Community ATTACH;FMTTYPE=image/jpeg:https://www.scilifelab.se/wp-content/uploads/2020/05/w2a5147-scaled.jpg ORGANIZER;CN="SciLifeLab Uppsala Fellows":MAILTO:events@scilifelab.se END:VEVENT END:VCALENDAR