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DTSTART;TZID=Europe/Stockholm:20211012T113000
DTEND;TZID=Europe/Stockholm:20211013T140000
DTSTAMP:20260403T213301
CREATED:20260305T085613Z
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SUMMARY:StorM Retreat 2026
DESCRIPTION:Welcome to the 2026 years STorM retreat \n\n\n\nAugust 26-27 \n\n\n\nVenue: Linköping University and Ekoxen Hotel\, Linköping\, Sweden \n\n\n\nThe Swedish Tumor Microenvironment (STorM) network leverages the power of internationally leading research groups in the field spanning across the entire country. The overarching aim of the program is to identify novel communication pathways within the tumor microenvironment that can be exploited as cancer drug targets and biomarkers. The program will foster cross-disciplinary studies which optimally combines experimental studies in cell and animal models\, correlative analyses of clinical samples\, and cutting-edge technology. \n\n\n\nRegistration deadline: April 19 \n\n\n\n\nRegister here\n\n\n\n\n\n\n\n\nProgram\n\n\n\n6th SToRM retreat programDownload\n\n\n\nSuggestions for accommodation (not covered by STorM) \n\n\n\nQuality Hotel Exoxen (location of the meeting\, close to LiU medical campus and hospital) \n\n\n\nElite Stora Hotellet (very central between railway station and meeting location\, walking distance) \n\n\n\nAnd Hotel (less central\, few min walking to meeting location\, closest to dinner location) \n\n\n\nPartners \n\n\n\nCancerfonden\, SciLifeLab Linköping\, Linköping University \n\n\n\nOrganizing committee \n\n\n\n \n\n\nLinda Bojmar\, Assistant Professor\, Docent\, Linköping University (Chair) \nCarolin Jönsson\, Research Engineer\, Linköping University \nJosefine Sandström\, Research Coordinator\, SciLifeLab\, Linköping University \nIkuan Sam\, Postdoctoral fellow\, Lund University \nDaniel Reed\, Postdoctoral fellow\, Lund University \nAnastasia Knyazeva\, Postdoctoral Fellow\, Umeå University \nHong Qian\, Professor\, Karolinska Institute
URL:https://www.scilifelab.se/event/storm-retreat-2026/
LOCATION:Quality Hotel Ekoxen\, Linköping\, Klostergatan 68\, Linköping\, 582 23\, Sweden
CATEGORIES:Community
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20211014T130000
DTEND;TZID=Europe/Stockholm:20211014T140000
DTSTAMP:20260403T213301
CREATED:20210903T121248Z
LAST-MODIFIED:20210929T143622Z
UID:10000428-1634216400-1634220000@www.scilifelab.se
SUMMARY:Campus Solna Seminar Series: Su Wang and Petter Sätterskog
DESCRIPTION:Welcome to join the Campus Solna Seminar Series – an  initiative to promote the fantastic science ongoing at Campus Solna and hopefully forge more internal communication and collaboration between within Campus Solna. The format consists of two 15 min talks (One speaker from the Alpha-building and one from the Gamma-building respectively)\, with an additional 5 min of questions. Presentation of ongoing (unpublished) projects is strongly encouraged. \n\n\n\nThe seminars are held Thursdays 13:00-13:50 and following current regulations\, they will be broadcast via zoom. \n\n\n\n \n\n\n\nThis week\n\n\n\nRevealing the radial organization of mitotic chromosomes by mGPSeqSu Wang (Magda Bienko\, Alpha 4) \n\n\n\nA generative model of a tumor microenvironmentPetter Sätterskog (Jean Hausser\, Alpha 5) \n\n\n\nRegistration\n\n\n\nRegister to receive the zoom-link. The same zoom link applies for all Campus Solna Seminar Series\, i.e. only one registration is necessary.
URL:https://www.scilifelab.se/event/campus-solna-seminar-series-su-wang-and-petter-satterskog/
CATEGORIES:Community
ORGANIZER;CN="SciLifeLab Solna PhD & Postdoc Council":MAILTO:phd-council@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20211015T090000
DTEND;TZID=Europe/Stockholm:20211015T093000
DTSTAMP:20260403T213301
CREATED:20210921T171433Z
LAST-MODIFIED:20211014T114429Z
UID:10000450-1634288400-1634290200@www.scilifelab.se
SUMMARY:Clinical Talks: Playing your way to healthy life
DESCRIPTION:On October 15\, it’s our great pleasure to host Professor Emma Lundberg once again. This time she will focus her Talk on her innovative company Mindforce GameLab. With the Fig platform\, patients can via gamification transform into “playtients”\, people with medical conditions who enjoy playing games with a purpose to establish healthy habits. Fig guides you on the journey to better health\, including improved behavioral administration of medicals for intended and sustainable use. \n\n\n\nEmma Lundberg SciLifeLab. \nFoto © Daniel Roos\n\n\n\nEmma is a Professor in cell biology proteomics at KTH Royal Institute of Technology\, Sweden\, and Director of the Cell Atlas\, part of the Human Protein Atlas program. She spent two and half sabbatical years as visiting Associate Professor at Stanford School of Medicine and the Chan-Zuckerberg Biohub. In the interface between bioimaging\, proteomics and artificial intelligence her research aims to define the spatiotemporal organization of the human proteome at a subcellular level\, with the goal to understand how variations and deviations in protein expression patterns can contribute to cellular function and disease.  \n\n\n\nShe also has a keen interest\, passion\, and fascination in the use of gaming for science and health applications. This led Emma to start her own company in 2017\, Skellefteå based Mindforce Game Lab\, with the goal to unleash the powerful potential gamification could offer medical healthcare. Simply phrased\, medicines will not work if people do not take them. Despite this\, only every other person takes their medication as prescribed. This is a fundamental challenge for treating many chronic diseases\, in terms of patient outcomes\, as well as the overall burden on healthcare systems. Although there are products that help patients with extrinsic motivations\, such as reminders and notifications\, Mindforce Game Lab focuses on intrinsic motivations; designing games that build in feelings of companionship\, belonging and purpose. Patients learn how healthy routines\, such as sleeping well\, eating well\, exercising regularly\, and adhering to prescribed medication\, can improve feelings of well-being. This builds an inner driving force to want to change behaviour and to maintain a healthy lifestyle. In late 2020 Mindforce Game Lab joined the AstraZeneca BioVentureHub and relocated the development team to Gothenburg. \n\n\n\nRegister to receive zoom link\n\n\n\n\n\n\n\nAfter our recent planning hiatus\, we now have the great pleasure to announce that “Clinical Talks” has been renewed for yet another exciting\, innovative\, and enlightening season. This season will focus on sustainable innovations within Life Sciences\, that have the potential to contribute to a better climate friendly future for our future generations. Also new this year is that the seminar is co-organized in a collaboration between SciLifeLab and KI Innovations. \n\n\n\nRead more
URL:https://www.scilifelab.se/event/playing-your-way-to-healthy-life/
LOCATION:Online event via Zoom
CATEGORIES:Event
ATTACH;FMTTYPE=image/jpeg:https://www.scilifelab.se/wp-content/uploads/2021/09/ClinicalTalks_Emma-Lundberg_1024-1.jpg
ORGANIZER;CN="Clinical Talks":MAILTO:precisionmedicine@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20211015T093000
DTEND;TZID=Europe/Stockholm:20211015T113000
DTSTAMP:20260403T213301
CREATED:20210922T144136Z
LAST-MODIFIED:20210922T173935Z
UID:10000451-1634290200-1634297400@www.scilifelab.se
SUMMARY:Virtual coffee drop in session - COVID-19 Data &  Code Reuse Competition 
DESCRIPTION:Location: Online via Zoom\n\n\n\nThe Swedish COVID-19 Data Portal invites you to join us for a Virtual coffee drop-in session and discussion about COVID-19 Data & Code Reuse Competition submissions. Take this opportunity to get support and ask questions about your ideas\, planned or  already started project for the competition. Drop-in for a chat with us and other participants\, we look forward to meet you. \n\n\n\nAbout the COVID-19 Data & Code Reuse Competition \n\n\n\nThe Swedish COVID-19 Data Portal invites researchers and general public to take part in the COVID-19 Data & Code Reuse Competition. Participants should complete small-scale projects that make use of publicly shared data and/or code to combat the COVID-19 pandemic or any future pandemics. \n\n\n\nWe welcome various types of project. The projects could\, for example\, involve the re-analysis of existing publicly available data using a different method\, or focus on a different aim\, or reuse publicly shared code to process a new set of data. Other possibilities include projects that produce individual visualizations\, dashboards presenting publicly shared data in a novel way or web-services devoted to data and analysis. The emphasis of the projects submitted should be to maximize the utility of existing data and/or code. \n\n\n\n\n\n\n\nRegister before October 14 to receive the Zoom link and allow planning of resources \n\n\n\nContact: SciLifeLab Data Centre\, datacentre@scilifelab.se \n\n\n\nRegister here
URL:https://www.scilifelab.se/event/virtual-coffee-drop-in-session-covid-19-data-code-reuse-competition/
LOCATION:Online event via Zoom
CATEGORIES:Event
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20211018T080000
DTEND;TZID=Europe/Stockholm:20211022T170000
DTSTAMP:20260403T213301
CREATED:20210602T093819Z
LAST-MODIFIED:20210602T094321Z
UID:10000395-1634544000-1634922000@www.scilifelab.se
SUMMARY:Python programming with applications to bioinformatics - ONLINE
DESCRIPTION:National course open for PhD students\, postdocs\, researchers and other employees in need of fundamental Python skills within all Swedish universities. \n\n\n\n\n\n\n\n\nApplication\n\n\n\n\n\n\n\n\nImportant dates \n\n\n\nApplication opens: June 21Application closes: September 4Confirmation to accepted students: September 8Responsible teachers: Nina Norgren\, Dimitris Bampalikis \n\n\n\nIf you do not receive information according to the above dates please contact: Nina Norgren (edu.intro-python@nbis.se) \n\n\n\nCourse fee \n\n\n\nNo course fee will be invoiced for online courses. However\, if you accept a position at the course and do not participate (no-show) you will be invoiced 2000 SEK.*Please note that NBIS cannot invoice individuals \n\n\n\nCourse description \n\n\n\nThis course provides a practical introduction to the writing of Python programs for the complete novice. Participants are led through the core aspects of Python illustrated by a series of example programs. Upon completion of the course\, attentive participants will be able to write simple Python programs from scratch and to customize more complex code to fit their needs. \n\n\n\nCourse content \n\n\n\nCore concepts about Python syntax: Data types\, blocks and indentation\, variable scoping\, iteration\, functions\, methods and argumentsDifferent ways to control program flow using loops and conditional testsRegular expressions and pattern matchingWriting functions and best-practice ways of making them usableReading from and writing to filesCode packaging and Python librariesHow to work with biological data using external libraries.\n\n\n\n\n\n\n\nLearning outcomes \n\n\n\nDescribe and apply basic concepts in Python\, such as:LoopsIf/else statementsFunctionsReading/writing to filesBeing able to edit and run Python codeWrite file-processing Python programs that produce output to the terminal and/or external filesCreate stand-alone python programs to process biological dataKnow how to develop your skills in Python after the course (including debugging)\n\n\n\nFormat \n\n\n\nPresentations and demonstrations. Practical exercises (either in the lab with assistants or on your own). Presentations will be given online\, mixed with exercises where teaching assistants will be available online to help with the exercises. \n\n\n\nEntry requirements \n\n\n\nThe course is suitable for complete beginners and assumes no prior programming experience (beyond the ability to use a text editor). A very basic knowledge of UNIX would be an advantage\, such as navigating through folders and issuing commands at a shell prompt. We will not teach UNIX in detail: Other courses are available at SciLifeLab for it. Make sure your laptop has python installed for the practical exercises. \n\n\n\nDue to limited space the course can accommodate a maximum of 30 participants. If we receive more applications\, participants will be selected based on several criteria. Selection criteria include correct entry requirements\, motivation to attend the course as well as gender and geographical balance. \n\n\n\nPlease note that NBIS training events do not provide any formal university credits. The training content is estimated to correspond to a certain number of credits\, however the estimated credits are just guidelines. If formal credits are crucial\, the student needs to confer with the home department before submitting a course application in order to establish whether the course is valid for formal credits or not.
URL:https://www.scilifelab.se/event/python-programming-with-applications-to-bioinformatics-online/
CATEGORIES:Course
ORGANIZER;CN="NBIS - National Bioinformatics Infrastructure Sweden":MAILTO:education@nbis.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20211018T151500
DTEND;TZID=Europe/Stockholm:20211018T161500
DTSTAMP:20260403T213301
CREATED:20210916T151516Z
LAST-MODIFIED:20210927T100311Z
UID:10000448-1634570100-1634573700@www.scilifelab.se
SUMMARY:The Svedberg seminar series: Ass. Prof. Prashant Singh
DESCRIPTION:SciLifeLab Fellow at Uppsala University \n\n\n\nLINK TO SEMINAR \n\n\n\n\n\n\n\n\n\nPrashant Singh is a SciLifeLab fellow and Assistant Professor hosted by the Division of Scientific Computing\, Department of Information Technology\, Uppsala University. His research interests involve developing machine learning and optimization methods to enable fast\, data-efficient analysis and processing of scientific data\, particularly in the domain of life sciences. \n\n\n\nScalable Likelihood-Free Parameter Inference of Stochastic Biochemical Reaction Networks\n\n\n\nAbstract: Parameter inference of stochastic time series models\, such as gene regulatory networks in the likelihood-free setting is a challenging task\, particularly when the number of parameters to be inferred is large. Recently\, data-driven machine learning models (neural networks in particular) have delivered encouraging results towards addressing the scalability\, efficiency and parameter inference quality of the likelihood-free parameter inference pipeline. In particular\, this talk will present a detailed discussion on neural networks as trainable\, expressive and scalable summary statistics of high-dimensional time series for parameter inference tasks. \n\n\n\nReference: \n\n\n\nM. Akesson\, P. Singh\, F. Wrede and A. Hellander\, “Convolutional Neural Networks as Summary Statistics for Approximate Bayesian Computation\,” in IEEE/ACM Transactions on Computational Biology and Bioinformatics\, doi: 10.1109/TCBB.2021.3108695. \n\n\n\nHost: Prof. Elisabeth Larsson\, Uppsala University
URL:https://www.scilifelab.se/event/the-svedberg-seminar-series-assoc-prof-prashant-singh/
LOCATION:Online event via Zoom
CATEGORIES:Event
ORGANIZER;CN="The Svedberg Seminar Series":MAILTO:thesvedberg@scilifelab.uu.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20211019T143000
DTEND;TZID=Europe/Stockholm:20211022T183000
DTSTAMP:20260403T213301
CREATED:20210524T143123Z
LAST-MODIFIED:20211007T121821Z
UID:10000392-1634653800-1634927400@www.scilifelab.se
SUMMARY:International Advisory Board meeting 2021
DESCRIPTION:The site visit has become a digital Zoom meeting. We welcome the International Advisory Board (IAB) of SciLifeLab to a 4-day meeting on October 19-22\, 2021. During the meeting\, we will discuss and seek guidance about SciLifeLab and its future plans. A background report\, prepared by the SciLifeLab management\, is sent to the IAB members. \n\n\n\n \n\n\n\n\nIAB Program\n\n\n\n\n\n\n\n\n\n\n\n\nPicture taken during the IAB visit in 2019. Left to right\, back to front row: Svante Pääbo\, Jonathan Knowles\, Yoshihide Hayashizaki\, Jo Bury\, Carl-Henrik Heldin\, Jan Ellenberg\, Annika Jenmalm Jensen\, Olli Kallioniemi\, Sarah Teichmann\, Sirpa Jalkanen\, Janet Jansson and Sören Brunak.
URL:https://www.scilifelab.se/event/international-advisory-board-meeting-2021/
CATEGORIES:Event
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20211020T080000
DTEND;TZID=Europe/Stockholm:20211022T170000
DTSTAMP:20260403T213301
CREATED:20210714T131729Z
LAST-MODIFIED:20210714T133644Z
UID:10000405-1634716800-1634922000@www.scilifelab.se
SUMMARY:Cryo-EM sample preparation and data collection
DESCRIPTION:The purpose of the course is to prepare and train Cryo-EM unit users in sample preparation methods\, introduce users to the image data acquisition workflow\, expand knowledge about cryo-EM methods among researchers and show that everyone can learn how to use cryo-EM for structure and cell biology. \n\n\n\nThe course is open for unit users or potential unit users\, such as PhD students\, postdocs\, and researchers within the life sciences who are curious and will profit from cryo-EM skills. Swedish and international course participants are welcome. To attend\, the course participants must have experience in basic electron microscopy and be familiar with structure or cell biology. \n\n\n\nThis course is supported by SciLifeLab\, CryoNET and Umeå University and organized by the SciLifeLab Cryo-EM unit\, both UmU and SU nodes together. \n\n\n\nImportant dates\n\n\n\nApplication should be submitted before September 17\, 2021 \n\n\n\nConfirmation to accepted participants: September 22\, 2021(If you don’t receive information about your application before September 27\, please contact hussein.haggag@umu.se \n\n\n\n\n\n\n\n\nCourse website\n\n\n\nApplication\n\n\n\n\n\n\n\n\nCourse organizers\n\n\n\nCamilla Holmlund and Michael Hall \n\n\n\nTeachers and course instructors\n\n\n\nLinda SandbladMichael HallLars-Anders CarlsonCamilla HolmlundAdditional teachers t.b.a\n\n\n\nSocial program\n\n\n\nA social program depending on the current corona restrictions will be communicated to the participants after acceptance.  \n\n\n\nCourse fee\n\n\n\nA course fee of 800 SEK\, including coffee and lunches\, will be invoiced to accepted participants after acceptance. \n\n\n\nCourse content\n\n\n\nThis course will cover practical aspects of cryo-EM sample preparation and data acquisition. \n\n\n\nTopics covered: \n\n\n\nBasic theory of vitreous water\, how to handle a cryo sample and consequencesPlunge freezing methods\, tools and cryo-transferSample and instrument requirements for single particle and tomography methodsImage data acquisition\, concept of low dose and the cryo-specific workflowIntroduction to automatic data acqui­sition software\, EPU\, TomographyIntroduction to cryo-EM image processing methods\n\n\n\nThe course consists of lectures\, cryo lab work\, demonstrations and practical exercises for all participants\, hands-on experiences of microscopy operation and discussions. A detailed schedule will be provided to accepted participant. \n\n\n\nCourse literature\n\n\n\nHandouts and material online. \n\n\n\nEntry requirements\n\n\n\nPriority will be given to researchers involved in project where the use of cryo-EM is needed\, which are to be briefly described upon application. \n\n\n\nThe course will be held at an advanced level\, assuming that participants have a master’s degree or equivalent in a technical life science discipline. It aims to be relevant for a broad research community\, also to participants not working in research environments using cryo-EM today. \n\n\n\nA maximum of 15 participants will be admitted. Selection criteria include correct entry requirements\, motivation to attend the course as well as gender balance. \n\n\n\nExamination \n\n\n\nParticipation in all parts of the course\, lectures\, lab\, microscopy demonstrations and evaluation are mandatory. SciLifeLab and Umeå University will provide successful participants with a course certificate and a recommendation for 1 ECTS \n\n\n\nPlease note that SciLifeLab training courses do not provide any formal university credits.The course content is estimated to correspond to a certain number of credits\, however the estimated credits are just guidelines.If formal credits are crucial\, the student needs to confer with the home department before course application\, whether the course is valid for formal credits or not.
URL:https://www.scilifelab.se/event/cryo-em-sample-preparation-and-data-collection/
CATEGORIES:Course
ORGANIZER;CN="UCEM Ume%C3%A5":MAILTO:hussein.haggag@umu.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20211021T130000
DTEND;TZID=Europe/Stockholm:20211021T140000
DTSTAMP:20260403T213301
CREATED:20210903T121706Z
LAST-MODIFIED:20211005T092652Z
UID:10000429-1634821200-1634824800@www.scilifelab.se
SUMMARY:Campus Solna Seminar Series: Wen Zhong and Oskar Kviman
DESCRIPTION:Welcome to join the Campus Solna Seminar Series – an  initiative to promote the fantastic science ongoing at Campus Solna and hopefully forge more internal communication and collaboration between within Campus Solna. The format consists of two 15 min talks (One speaker from the Alpha-building and one from the Gamma-building respectively)\, with an additional 5 min of questions. Presentation of ongoing (unpublished) projects is strongly encouraged. \n\n\n\nThe seminars are held Thursdays 13:00-13:50 and following current regulations\, they will be broadcast via zoom. \n\n\n\n \n\n\n\nThis week\n\n\n\nNext-generation plasma proteome profiling to monitor health and diseaseWen Zhong (Linn Fagerberg\, alpha 6)  \n\n\n\n \n\n\n\nEnsembles of Variational ApproximationsOskar Kviman (Jens Lagergren\, gamma 6) \n\n\n\nRegistration\n\n\n\nRegister to receive the zoom-link. The same zoom link applies for all Campus Solna Seminar Series\, i.e. only one registration is necessary.
URL:https://www.scilifelab.se/event/campus-solna-seminar-series-wen-zhong-and-oskar-kviman/
CATEGORIES:Community
ORGANIZER;CN="SciLifeLab Solna PhD & Postdoc Council":MAILTO:phd-council@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20211021T143000
DTEND;TZID=Europe/Stockholm:20211021T151500
DTSTAMP:20260403T213301
CREATED:20211005T093455Z
LAST-MODIFIED:20211005T093615Z
UID:10000461-1634826600-1634829300@www.scilifelab.se
SUMMARY:[Big Talks] – Transposon Genomics — From Single Loci To Single Cells
DESCRIPTION:Invited speaker \n\n\n\nMolly Gale Hammell\, Associate Professor\, Cold Spring Harbor Laboratory\, USA \n\n\n\n \n\n\n\nAbstract\n\n\n\nTransposable Elements (TEs) are sequences in the human genome that have (or once had) the ability to mobilize from one location in the genome to another. Most of the TEs that currently exist in the human genome are fixed and unable to mobilize\, but many of these sequences have some residual level of functionality. These residual functions might include: the ability to bind DNA- or RNA-binding factors and act as regulatory elements\, the ability to generate RNA transcripts\, and/or the ability to encode proteins. Because TEs are extremely abundant in the human genome\, covering nearly 45% of the sequence space\, active TEs can have a large\, and often deleterious\, impact on host cell function. Multiple studies have shown aberrant elevation of TE expression in aging-associated diseases\, such as neurodegeneration and cancer. However\, establishing a causal role for TE activity in these contexts requires tracking down the individual TE loci that are active\, and distinguishing these from the thousands of other TE loci that are silent and/or non-functional. This is still an unsolved problem in the field of transposon genomics\, but new tools and technologies are making the problem more tractable. These include long-read technologies\, and improved statistical methods for analyzing TE expression and integrating TE multi-omics datasets. Once aberrantly active TE loci are identified\, it’s often important to know which cell type is harboring these activated TEs\, and whether certain cells are more vulnerable to TE activity than others. Integrating TE expression analysis into single-cell genomics workflows is crucial to understanding how these elements contribute to human disease. I will present recent results from my lab that tackle these issues in the context of neurodegeneration\, where elevated transposons are thought to contribute to neurotoxicity\, and may also contribute to neuroinflammation.  \n\n\n\nBiography\n\n\n\n\n\n\n\nThe Gale Hammell lab uses a combination of computational and experimental methods to understand how gene regulatory networks are perturbed in human disease. This includes an emphasis on developing novel tools for the statistical analysis of high-throughput data\, developing novel algorithms for modeling the flow of signals through genetic pathways\, and importantly\, testing these models using the tools of molecular genetics. One particular focus of the M. Hammell lab is to apply these novel statistical analysis methods to better understand how transposable elements are normally controlled. Mounting evidence has implicated transposon activity in a host of human diseases\, with particular evidence for activation in several neurodegenerative diseases\, including Amyotrophic lateral sclerosis (ALS)\, Fronto-Temporal Dementia (FTD)\, and Alzheimer’s Disease (AD). By combining the power of systems-level\, high-throughput data analysis with patient-derived ALS\, FTD\, and AD tissue samples\, the lab aims to better understand how these viral-like sequences contribute to cell death and disease. \n\n\n\n\n\n\n\nHost: Louella Vasquez\, NBIS Lund (louella.vasquez@scilifelab.se) \n\n\n\nDate: October 21\, 14:30 – 15:15 CET online on YouTube \n\n\n\nBroadcast link (live event): SBW YouTube channelThe talk will also be available afterwards on the SciLifeLab YouTube channel.More information about the Swedish Bioinformatics Workshop here.
URL:https://www.scilifelab.se/event/big-talks-transposon-genomics-from-single-loci-to-single-cells/
CATEGORIES:Event
ORGANIZER;CN="Swedish Bioinformatics Workshop":MAILTO:louella.vasquez@scilifelab.se
LOCATION:https://www.scilifelab.se/event/big-talks-transposon-genomics-from-single-loci-to-single-cells/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20211021T170000
DTEND;TZID=Europe/Stockholm:20211021T173000
DTSTAMP:20260403T213301
CREATED:20210928T135950Z
LAST-MODIFIED:20211005T094033Z
UID:10000457-1634835600-1634837400@www.scilifelab.se
SUMMARY:Clinical Talks: Writing the Future
DESCRIPTION:Writing the Future\n\n\n\nOn October 21\, Dr. Emily Leproust will talk about her mission with co-founding Twist Bioscience\, and how their revolutionary oligosynthesis plattform is writing the future with DNA.  \n\n\n\nTwist Bioscience’s innovative silicon-based DNA Synthesis Platform is empowering our customers to realise their research goals faster. Twist offers DNA synthesis at an unmatched scale and price point\, without compromising on precision or quality. Here we discuss how DNA synthesis at scale can make traditional molecular biology approaches redundant in labs working with plasmid vectors; can power massive\, explicit diversity in CRISPR and antibody variant libraries; and can underpin NGS Target Enrichment Solutions with exceptional performance and unmatched speed in customisation. We’ll look at how these tools are helping drive innovation in a variety of research and application areas including cancer research\, drug discovery\, infectious disease and even data storage. \n\n\n\nAs an early pioneer in the high-throughput synthesis and sequencing of DNA\, Dr. Leproust is disrupting markets to enable the exponential growth of DNA-based applications including chemicals/materials\, diagnostics\, therapeutics\, food and digital data storage. In 2020\, BIO presented her with the Rosalind Franklin Award for Leadership. Foreign Policy named her one of their 100 Leading Global Thinkers and Fast Company named her one of the Most Creative People in Business. Prior to Twist Bioscience\, she held escalating positions at Agilent Technologies where she architected the successful SureSelect product line that lowered the cost of sequencing and elucidated mechanisms responsible for dozens of Mendelian diseases. She also developed the Oligo Library Synthesis technology\, where she initiated and led product and business development activities for the team. Dr. Leproust designed and developed multiple commercial synthesis platforms to streamline microarray manufacturing and fabrication. She serves on the Board of Directors of CM Life Sciences and is a co-founder of Petri\, an accelerator for start-ups at the forefront of engineering and biology. Dr. Leproust has published over 30 peer-reviewed papers – many on applications of synthetic DNA\, and is the author of numerous patents. She earned her Ph.D. in Organic Chemistry from University of Houston and her M.Sc. in Industrial Chemistry from the Lyon School of Industrial Chemistry. \n\n\n\nregistration\n\n\n\n\n\n\n\nSeason 5\, will be held September until December 2021 with scheduled Talks\, during Friday mornings 09-09:30 am via ZOOM (with some time-zone friendly adjustments for our international speakers). Each session consists of a talk given by our invited speaker followed by Q&A. The seminar is an open educational seminar series for our ever-expanding Life Science community. \n\n\n\nAfter our recent planning hiatus\, we now have the great pleasure to announce that “Clinical Talks” has been renewed for yet another exciting\, innovative\, and enlightening season. This season will focus on sustainable innovations within Life Sciences\, that have the potential to contribute to a better climate friendly future for our future generations. Also new this year is that the seminar is co-organized in a collaboration between SciLifeLab and KI Innovations. \n\n\n\nRead more
URL:https://www.scilifelab.se/event/clinical-talks-writing-the-future/
LOCATION:Online event via Zoom
CATEGORIES:Event
ATTACH;FMTTYPE=image/jpeg:https://www.scilifelab.se/wp-content/uploads/2021/09/ClinicalTalks_Season5_twitter_1024.jpg
ORGANIZER;CN="Clinical Talks":MAILTO:precisionmedicine@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20211025T080000
DTEND;TZID=Europe/Stockholm:20211029T170000
DTSTAMP:20260403T213301
CREATED:20210524T095145Z
LAST-MODIFIED:20211027T085846Z
UID:10000391-1635148800-1635526800@www.scilifelab.se
SUMMARY:Epigenomics Data Analysis: from Bulk to Single Cell (ONLINE)
DESCRIPTION:National workshop open for PhD students\, postdocs\, researchers and other employees within Swedish academia. This course is run by the National Bioinformatics Infrastructure Sweden (NBIS) \n\n\n\n \n\n\n\n\nCourse website\n\n\n\nApplication\n\n\n\n\nImportant dates\n\n\n\nApplication opens:  nowApplication closes: 2021-10-10Confirmation to accepted students:  2021-10-14 \n\n\n\nResponsible teachers\n\n\n\nAgata Smialowska\, Olga Dethlefsen\, Jakub WestholmPlease contact edu.epigenomics@nbis.se for course specific questions. \n\n\n\nWorkshop fee\n\n\n\nThis online training event has no fee. However\, if you accept a position at the workshop and do not participate (no-show) you will be invoiced 2000 SEK.  \n\n\n\n*Please note that NBIS cannot invoice individuals. \n\n\n\nWorkshop content\n\n\n\nThis workshop aims to introduce the best practice bioinformatics methods for processing\, analyses and integration of epigenomics and functional genomics data. \n\n\n\nTopics covered include\n\n\n\nData processing and analyses for differential methylation with Illumina EPIC arrays and Bisulfite-seq;ChIP-seq and ATAC-seq: peak calling\, peak independent/dependent quality metrics\, differential binding and differential accessibility analysis; motif enrichment;Functional analysis\, including finding nearest genes and custom features\, over-represented GO terms and Reactome pathways;Advanced ChIP methods: CUT&RUN\, CUT&Tag\, use of spike-ins in ChIP-seq;Integrative visualisations of epigenomics datasets;Introduction to nf-core pipelines for processing and analysis of epi- and functional genomics data.Basic multi-omics exploration and integration;Introduction to analysis of single cell functional genomics data (scATAC-seq). \n\n\n\nEntry requirements\n\n\n\nRequired for being able to follow the workshop and complete the computer exercises: \n\n\n\nBYOL\, bring your own laptop with R and RStudio installed;Basic knowledge in Linux;Basic programming experience\, preferably in R.\n\n\n\nDesirable \n\n\n\nExperience working on the SNIC center Uppmax or another HPC. We encourage participants to run the linked Uppmax tutorial before the workshop;Previous experience with NGS data analyses;Completing NBIS workshops “Introduction to Bioinformatics using NGS data” and “R Programming Foundations for Life Scientists” or equivalent.\n\n\n\nDue to limited capacity the workshop can accommodate maximum of 25 participants. If we receive more applications\, participants will be selected based on several criteria. Selection criteria include correct entry requirements\, motivation to attend the workshop as well as gender and geographical balance. \n\n\n\nPlease note that NBIS training events do not provide any formal university credits. \n\n\n\nThe training content is estimated to correspond to a certain number of credits\, however the estimated credits are just guidelines.If formal credits are crucial\, the student needs to confer with the home department before course application\, whether the course is valid for formal credits or not.
URL:https://www.scilifelab.se/event/epigenomics-data-analysis-from-bulk-to-single-cell-online/
CATEGORIES:Course
ORGANIZER;CN="NBIS - National Bioinformatics Infrastructure Sweden":MAILTO:education@nbis.se
LOCATION:
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20211026T110000
DTEND;TZID=Europe/Stockholm:20211026T115000
DTSTAMP:20260403T213301
CREATED:20211014T073033Z
LAST-MODIFIED:20211110T152453Z
UID:10000463-1635246000-1635249000@www.scilifelab.se
SUMMARY:Uppsala PhD&Postdoc seminars: Simone Fouché & Jana Immenschuh
DESCRIPTION:Welcome to the very first SciLifeLab Uppsala PhD&Postdoc seminars!We are very happy to host exciting talks by PhD students and Postdocs from a great variety of fields within SciLifeLab. \n\n\n\nThe seminars will take place every Tuesday from 11:00 to 11:50 \n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\nFor this very first occasion the seminars will be:\n\n\n\nTowards unravelling the mystery of germline-restricted chromosomesSimone Fouché\, Postdoc at the Suh Group\, Dept. of Organismal Biology – Systematic BiologyMapping and characterization of aromatase gene expression in the male and female young adult rat brainJana Immenschuh\, PhD student at the Neuropsychopharmacology Group\, Dept. of Neuroscience \n\n\n\nAbstracts\n\n\n\nTitle: Towards unravelling the mystery of germline-restricted chromosomes \n\n\n\nSummary:Not all cells in eukaryotic organisms contain the same genome\, but rather programmed DNA elimination occurs extensively across the Tree of Life\, whereby fragments of the genome or entire chromosomes are removed during germline-soma differentiation. In zebra finch\, a massive chromosome\, the germline-restricted chromosome (GRC) is present in the germline and absent in the soma. Cytogenetic data suggest GRCs are widely distributed among songbirds. Despite the wide occurrence of programmed DNA elimination\, the mechanisms of programmed DNA elimination\, the function and the evolutionary significance of the phenomenon\, are poorly understood. At present we are working on a reference assembly for the GRC in zebra finch in order to shed some light on the emergence and evolution of this enigmatic chromosome. Specifically we would like show whether: 1. Whether the GRC is always maternally inherited? 2. What is the population level variation and are some regions maintained by selection? 3. Which regions of the genome are more likely to be copied to the GRC\, regions with functions related to development or highly recombining regions of regular chromosomes? \n\n\n\nTitle: Mapping and characterization of aromatase gene expression in the male and female young adult rat brain \n\n\n\nSummary:The enzyme aromatase (Cyp19a1 gene) catalyzes the biosynthesis of estrogens from androgens. Besides several peripheral tissues\, it is expressed in specific brain regions that are of relevance to emotional and cognitive functions in mammalian species\, including rats and humans. Of interest\, aromatase seems to be involved in non-reproductive functions in the brain\, such as regulation of neurogenesis\, synaptic transmission and neuroprotection and might be expressed in a sex-dependent manner. Investigation of its expression throughout the brain has shown to be outdated and imprecise\, and is lacking the identification of sub regions with known sexual dimorphisms or functions related to sex differences in both males and females. Additionally\, little is known about the identity of the neurons expressing aromatase. The present study sought to map the expression pattern of Cyp19a1 throughout the brain of young adult rats of both sexes and elucidate sex differences\, as well as characterize in an exploratory fashion the cell types expressing this gene. The findings will advance the knowledge on aromatase and its role in the brain. As gonadal hormones affect the brain as well as mental health in a profound manner\, this study might shed light on some of the underlying molecular underpinnings.
URL:https://www.scilifelab.se/event/scilifelab-uppsala-phdpostdoc-seminars-simone-fouche-jana-immenschuh/
LOCATION:Online event via Zoom
CATEGORIES:Community
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20211026T130000
DTEND;TZID=Europe/Stockholm:20211026T160000
DTSTAMP:20260403T213301
CREATED:20210928T124945Z
LAST-MODIFIED:20211018T141735Z
UID:10000456-1635253200-1635264000@www.scilifelab.se
SUMMARY:DNP inauguration ceremony
DESCRIPTION:We are very happy to announce the unique collaboration between AstraZeneca and University of Gothenburg on advanced NMR technology\, manifested in the inauguration ceremony of our new DNP-NMR instrument! \n\n\n\nWelcome to the DNP inauguration ceremony to celebrate the DNP-NMR instrument investment at the Swedish NMR Centre\, University of Gothenburg! \n\n\n\nThe ceremony will take place between 13.00 – 16.00 on October 26 in lecture hall Birgit Thilander\, Medicinaregatan 3\, Gothenburg. \n\n\n\nInvited guest speaker professor Lyndon Emsley from EPFL Lausanne will close the ceremony by giving a lecture between 15.00 – 16.00. \n\n\n\nPlease respond before October 16. \n\n\n\nregistration\n\n\n\nProgram\n\n\n\n13.00Welcome remarksWelcome – Göran Karlsson\, Director Swedish NMR Centre\, and Staffan Schantz\, APS AstraZenecaGothenburg ecosystem view – Matti Ahlqvist\, AstraZeneca Gothenburg Executive Site DirectorPharmaceutical development – Piet van den Oetelaar\, Head OPD/AstraZenecaUniversity Research Infrastructures – Göran Hilmersson\, Dean\, The Faculty of Science\, University of Gothenburg.13.45Tour to the new DNP-NMR instrumentArthur Pinon\, SNC14.30Light snacks & refreshments15.00Structure Activity Relations in Materials from DNP-NMRLyndon Emsley\, EPFL Lausanne16.00Closing\n\n\n\n \n\n\n\nOn behalf of the inauguration ceremony team\, \n\n\n\nStaffan Schantz\, AstraZeneca\, Göran Karlsson\, University of Gothenburg\, Ulrika Brath\, University of Gothenburg Nina Berg\, AstraZeneca 
URL:https://www.scilifelab.se/event/dnp-inauguration-ceremony/
LOCATION:Birgit Thilander Lecture Hall\, Medicinaregatan 3\, Göteborg
CATEGORIES:Event
ATTACH;FMTTYPE=image/jpeg:https://www.scilifelab.se/wp-content/uploads/2021/09/image001.jpg
ORGANIZER;CN="Swedish NMR Centre":MAILTO:info@nmr.gu.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20211027T080000
DTEND;TZID=Europe/Stockholm:20211029T170000
DTSTAMP:20260403T213301
CREATED:20210906T122129Z
LAST-MODIFIED:20210906T122916Z
UID:10000439-1635321600-1635526800@www.scilifelab.se
SUMMARY:nf-core hackathon
DESCRIPTION:Mark your calendars to join us for the October 2021 nf-core hackathon! \n\n\n\nWith the recent release of the new nf-core template for Nextflow’s DSL2\, in this event we will be going full-steam ahead with conversion of nf-core pipelines from DSL1 to DSL2. The main objectives of this hackathon will be adding nf-core modules and rewriting existing pipelines to the new Nextflow language format. \n\n\n\nFor Nextflow novices\, we will be looking for help in writing Nextflow modules of commonly used bioinformatics tools. \n\n\n\nFor more experienced developers we hope for contributions to writing subworkflows and pipeline code. \n\n\n\nIn the spirit of collaboration and knowledge sharing\, we plan to pair up both novices and experienced developers in pair programming to help get newcomers up to speed on writing and contributing nf-core modules through a pair-programming session for a limited number of participants. Make sure to sign up by September 27\, 2021 to participate in pair-programming! \n\n\n\nThis event is entirely virtual and we are attempting to support people in all timezones. Do get in touch with us if you’d like to help us out! \n\n\n\nRead more and sign up
URL:https://www.scilifelab.se/event/nf-core-hackathon/
CATEGORIES:Event
ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2021/09/nf-core-logo.png
LOCATION:https://www.scilifelab.se/event/nf-core-hackathon/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20211027T151500
DTEND;TZID=Europe/Stockholm:20211027T164500
DTSTAMP:20260403T213301
CREATED:20211011T121542Z
LAST-MODIFIED:20211012T094117Z
UID:10000462-1635347700-1635353100@www.scilifelab.se
SUMMARY:SciLifeLab COVID-19 seminars: Aaron Bivins and Anna Székely
DESCRIPTION:The third seminar in this series starts with Aaron Bivins\, Post-Doctoral Research Associate\, Department of Civil & Environmental Engineering & Earth Sciences\, University of Notre Dame\, who will talk about Wastewater surveillance for COVID-19 in a vaccinated world.  \n\n\n\nAnna Székely\, Associate Professor\, Researcher at the Department of Aquatic Sciences and Assessment; Section for Ecology and Biodiversity\, Swedish University of Agricultural Sciences (SLU)\, then continues the seminar by talking about Experiences and challenges of Swedish wastewater measurements: from research project to national monitoring \n\n\n\nHost:  Zeynep Cetecioglu Gurol\, KTH \n\n\n\n\n\n\n\nRegistration is mandatory to get the Zoom link for the event \n\n\n\n\n\n\n\n\n\n\n\n\nREGISTRATION\n\n\n\n\n\n\n\n\n\nBIOS and ABSTRACTS\n\n\n\n\n\n\n\n\n\n\n\n\nProgram\n\n\n\n15:15Wastewater surveillance for COVID-19 in a vaccinated world Aaron Bivins\, Post-Doctoral Research Associate\, University of Notre Dame  16:00Experiences and challenges of Swedish wastewater measurements: from research project to national monitoring Anna Székely\, Associate Professor\, Researcher\, SLU
URL:https://www.scilifelab.se/event/scilifelab-covid-19-seminars-aaron-bivins-and-anna-szekely/
LOCATION:Online event via Zoom
CATEGORIES:Event
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20211028T130000
DTEND;TZID=Europe/Stockholm:20211028T140000
DTSTAMP:20260403T213301
CREATED:20210903T121919Z
LAST-MODIFIED:20211014T094043Z
UID:10000430-1635426000-1635429600@www.scilifelab.se
SUMMARY:Campus Solna Seminar Series: Benilde Bonnefille and Deike Omnus
DESCRIPTION:Welcome to join the Campus Solna Seminar Series – an  initiative to promote the fantastic science ongoing at Campus Solna and hopefully forge more internal communication and collaboration between within Campus Solna. The format consists of two 15 min talks (One speaker from the Alpha-building and one from the Gamma-building respectively)\, with an additional 5 min of questions. Presentation of ongoing (unpublished) projects is strongly encouraged. \n\n\n\nThe seminars are held Thursdays 13:00-13:50 and following current regulations\, they will be broadcast via zoom. \n\n\n\n \n\n\n\nThis week\n\n\n\nNontarget analysis of river surface samples from Bangladesh: preliminary resultsBenilde Bonnefille (Jonathan Martin\, alpha 2)  \n\n\n\n \n\n\n\nA novel heat shock protein activates the Lon protease at the onset of proteotoxic stressDeike Omnus (Kristina Jonas\, gamma 5) \n\n\n\nRegistration\n\n\n\nRegister to receive the zoom-link. The same zoom link applies for all Campus Solna Seminar Series\, i.e. only one registration is necessary.
URL:https://www.scilifelab.se/event/campus-solna-seminar-series-benilde-bonnefille-and-deike-omnus/
CATEGORIES:Community
ORGANIZER;CN="SciLifeLab Solna PhD & Postdoc Council":MAILTO:phd-council@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20211028T130000
DTEND;TZID=Europe/Stockholm:20211028T140000
DTSTAMP:20260403T213301
CREATED:20210930T150158Z
LAST-MODIFIED:20211014T151926Z
UID:10000459-1635426000-1635429600@www.scilifelab.se
SUMMARY:[Drug Discovery Seminars] Targeting the oncogenic TGFβ signaling pathway in cancer to inhibit invasion and metastasis
DESCRIPTION:Maréne Landström \n\n\n\nOctober 28\, 13:00-14:00 \n\n\n\n \n\n\n\nregistration\n\n\n\nWelcome to join this Drug Discovery Seminar hosted by the Drug Discovery and Development Platform. \n\n\n\nPresenter: \n\n\n\nProfessor Maréne Landström\, M.D.\, PhD \n\n\n\nDept. Medical Biosciences\, Umeå University \n\n\n\nMaréne Landström is a professor in Pathology at Department of Medical Biosciences\, Umeå University\, Sweden. She has made her postdoctoral training at the Ludwig Institute of Cancer Research\, Uppsala Branch and have also been a group leader at Department of Immunology\, Genetics and Pathology\, Uppsala University before taking on her current position. \n\n\n\nAbstract: \n\n\n\nTransforming growth factor beta (TGFb) is frequently overexpressed in several forms of cancer including prostate cancer and this has been shown to correlate with poor prognosis. TGFb is transducing its canonical and non-canonical signals via its transmembrane TGFb Type II and Type I receptors (TbRII/TbRI) which are serine-threonine kinases. We have found that the TbRI undergoes proteolytic cleavage in cancer cells in a manner dependent on the ubiquitin-ligase tumor necrosis factor (TNF) receptor-associated factor 6 (TRAF6). The intracellular domain of TbRI (TbRI-ICD) is released from the cell membrane\, soluble and is transported to the nucleus in some specific forms of cancer to promote expression of genes causing invasion and metastatic growth. In collaboration with SciLifeLab DDD we have generated potential therapeutic antibodies to target this pathway which we are investigating the function of\, in our established preclinical models for prostate cancer.
URL:https://www.scilifelab.se/event/drug-discovery-seminars-targeting-the-oncogenic-tgf%ce%b2-signaling-pathway-in-cancer-to-inhibit-invasion-and-metastasis/
LOCATION:Online event via Zoom
CATEGORIES:Event
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20211028T163000
DTEND;TZID=Europe/Stockholm:20211028T180000
DTSTAMP:20260403T213301
CREATED:20211019T131708Z
LAST-MODIFIED:20211027T090347Z
UID:10000469-1635438600-1635444000@www.scilifelab.se
SUMMARY:Meet the Community Committees of SciLifeLab Campus Solna
DESCRIPTION:Committees of SciLifeLab warmly welcome you to the Networking event at SciLifeLab on 28th of October\, 16:30\, Gamma 2 kitchen. \n\n\n\nYou will meet committees of ScilifeLab: \n\n\n\n    – Phd and Postdoc Council \n\n\n\n    – Diversity\, Equity and Inclusion Committee \n\n\n\n    – Public Outreach and Engagement Committee \n\n\n\nYou will learn what we are doing and how you can contribute and participate! \n\n\n\nAfterwards – SciLifeLab Pub. \n\n\n\nLooking forward to meet you! \n\n\n\nBest regards\,Committees of SciLifeLab 
URL:https://www.scilifelab.se/event/meet-the-committees-of-scilifelab-28th-oct-1630/
LOCATION:Gamma 2 Lunchroom\, SciLifeLab\, Tomtebodavägen 23\, Solna\, Sweden
CATEGORIES:Community
ORGANIZER;CN="SciLifeLab Solna PhD & Postdoc Council":MAILTO:phd-council@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20211029T090000
DTEND;TZID=Europe/Stockholm:20211029T093000
DTSTAMP:20260403T213301
CREATED:20211014T115257Z
LAST-MODIFIED:20211028T115510Z
UID:10000464-1635498000-1635499800@www.scilifelab.se
SUMMARY:Clinical Talks: Blood-based methods for predicting the day of labor
DESCRIPTION:On October 29\, we will host a dual presentation with Dr. Ina Stelzer and Associate Professor Brice Gaudillière. At the Stanford School of Medicine Clinical Gaudillière laboratory\, Ina and Brice have developed a groundbreaking multi-omics approach to track the maternal metabolome\, proteome and immunome to predict exact labor onset. Estimating the time of delivery is of high clinical importance to minimize pre- and post-term deviations causing complications and suffering with ultimately more streamlined use of medical resources for a sustainable future. \n\n\n\n \n\n\n\nRead more about clinical talks\n\n\n\n\n\n\n\nIna is a molecular biologist and immunologist with an extensive background in pregnancy immunology. She obtained her PhD in Immunology 2017 from the University Medical Center Hamburg-Eppendorf (part of the University of Hamburg). Her work then focused on the immunology of pregnancy and feto-maternal immune crosstalk with a focus on fetal origin of disease development later in life. Ina is currently pursuing her postdoctoral research at Stanford University in the Gaudillière laboratory. Building on her expertise in preclinical (mouse) models of pregnancy and translational systems immunology\, her research leverages state-of-the-art single cell proteomic techniques (suspension and imaging mass cytometry) to study feto-maternal immune adaptations in healthy and pathological pregnancies with the goal to improving the health of mothers and their children. Her current K99/R00-funded work investigates the neuro-immune axis in normal pregnancy and the pathogenesis of pregnancy complications. While at Stanford during 2021\, Ina also recently completed the prestigious Stanford University Graduate School of Business organized Stanford Ignite certificate program. \n\n\n\n\n\n\n\nAssociate Professor Brice Gaudillière initially studied Engineering at Ecole Polytechnique in Paris before completing an MD-PhD degree from the Harvard-MIT Health Sciences and Technology program in 2009. During his postdoctoral fellowship at Stanford University in Dr. Garry Nolan’s laboratory\, he developed and standardized a pipeline to implement CyTOF in clinical studies. Brice is also a Board Certified Anesthesiologist and works clinically in the operating room 25% of his time. \n\n\n\nGaudilliere’s research group combines high parameter mass cytometry (suspension and imaging mass cytometry) with other proteomics approaches to study how the human immune system responds and adapts to physiological or pathological stressors. Ongoing studies in the Gaudilliere lab focus on several clinical scenarios including\, 1) surgical recovery and traumatic injury (NIGMS R35\, Stanford ITI\, Anesthesia department FIDL\, 2) pregnancy and preterm birth (Doris Duke Foundation\, Stanford Prematurity Center grants from the Bill and Melinda Gates and the March of Dimes Foundation\, 3) Host immune response to COVID-19 infection (FAST grant)\, 4) neurocognitive recovery after stroke (PHIND grant). \n\n\n\nregister here
URL:https://www.scilifelab.se/event/blood-based-methods-for-predicting-the-day-of-labor/
LOCATION:Online event via Zoom
CATEGORIES:Event
ATTACH;FMTTYPE=image/jpeg:https://www.scilifelab.se/wp-content/uploads/2021/09/ClinicalTalks_Season5_twitter_1024.jpg
ORGANIZER;CN="Clinical Talks":MAILTO:precisionmedicine@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20211102T090000
DTEND;TZID=Europe/Stockholm:20211102T100000
DTSTAMP:20260403T213301
CREATED:20210902T060701Z
LAST-MODIFIED:20211019T152930Z
UID:10000425-1635843600-1635847200@www.scilifelab.se
SUMMARY:BioImage Informatics Call4Help Webinar: CellPose
DESCRIPTION:For our next Call4Help session we are organizing a tool-presentation seminar about CellPose\, a generalist algorithm for cell and nuclei segmentation. CellPose is a deep learning-based segmentation method trained on a wide range of image types. It can be applied to both 2D and 3D images.  \n\n\n\nDuring this seminar we will explore different ways to run CellPose\, including demos powered by the ImJoy server which aim to make it easier for users to analyse large datasets in computing clusters. The webinar will be given by Gisele Miranda (BIIF) and Wei Ouyang (KTH\, developer of ImJoy) and will take place on November 2nd\, 09:00-10:00. There will be time for questions and discussion\, so we hope this event to be very interactive. Please register here. \n\n\n\nregistration\n\n\n\nImportant links\n\n\n\nhttps://github.com/MouseLand/cellposehttps://imjoy.io/
URL:https://www.scilifelab.se/event/bioimage-informatics-call4help-5/
CATEGORIES:Event
ORGANIZER;CN="Bioimage Informatics Unit":MAILTO:biif@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20211103T151500
DTEND;TZID=Europe/Stockholm:20211103T164500
DTSTAMP:20260403T213301
CREATED:20211021T083636Z
LAST-MODIFIED:20211027T132303Z
UID:10000472-1635952500-1635957900@www.scilifelab.se
SUMMARY:SciLifeLab COVID-19 seminars: Lars Juhl Jensen and Sonja Aits
DESCRIPTION:The fourth seminar in this series starts with Lars Juhl Jensen\, Professor\, Novo Nordisk Foundation Center for Protein Research\, Faculty of Health and Medical Sciences\, University of Copenhagen\, who will talk about From intraspecies protein networks to host–pathogen networks.  \n\n\n\nSonja Aits\, Associate senior lecturer at Cell Death\, Lysosomes and Artificial Intelligence\, Lund University\, then continues the seminar with a talk on Text mining for COVID-19 knowledge extraction \n\n\n\n\n\n\n\n Registration is mandatory to get the Zoom link for the event  \n\n\n\n\nREGISTRATION\n\n\n\nBIOS & ABSTRACTS
URL:https://www.scilifelab.se/event/scilifelab-covid-19-seminars-lars-juhl-jensen-and-sonja-aits/
LOCATION:Online event via Zoom
CATEGORIES:Event
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20211104T130000
DTEND;TZID=Europe/Stockholm:20211104T140000
DTSTAMP:20260403T213301
CREATED:20210903T122106Z
LAST-MODIFIED:20211019T152007Z
UID:10000431-1636030800-1636034400@www.scilifelab.se
SUMMARY:Campus Solna Seminar Series: Eva Gracia Villacampa and Lilit Nersisyan
DESCRIPTION:Welcome to join the Campus Solna Seminar Series – an  initiative to promote the fantastic science ongoing at Campus Solna and hopefully forge more internal communication and collaboration between within Campus Solna. The format consists of two 15 min talks (One speaker from the Alpha-building and one from the Gamma-building respectively)\, with an additional 5 min of questions. Presentation of ongoing (unpublished) projects is strongly encouraged. \n\n\n\nThe seminars are held Thursdays 13:00-13:50 and following current regulations\, they will be broadcast via zoom. \n\n\n\n \n\n\n\nThis week\n\n\n\nGenome-wide Spatial Expression Profiling in FFPE tissuesEva Gracia Villacampa (Joakim Lundeberg\, alpha 3)  \n\n\n\n \n\n\n\nRNA degradation analysis reveals ribosome dynamics in complex microbiome samplesLilit Nersisyan (Vicent Pelechano\, gamma 5) \n\n\n\nRegistration\n\n\n\nRegister to receive the zoom-link. The same zoom link applies for all Campus Solna Seminar Series\, i.e. only one registration is necessary.
URL:https://www.scilifelab.se/event/campus-solna-seminar-series-eva-gracia-villacampa-and-lilit-nersisyan/
CATEGORIES:Community
ORGANIZER;CN="SciLifeLab Solna PhD & Postdoc Council":MAILTO:phd-council@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20211108T093000
DTEND;TZID=Europe/Stockholm:20211108T103000
DTSTAMP:20260403T213301
CREATED:20210609T090521Z
LAST-MODIFIED:20210826T100254Z
UID:10000400-1636363800-1636367400@www.scilifelab.se
SUMMARY:Career path discussions with Jennifer Lippincott-Schwartz
DESCRIPTION:Jennifer Lippincott-Schwartz from the Howard Hughes Medical Institute will give an account of her career path and discuss with students and postdocs at 09.30 in the SciLifeLab Air&Fire auditorium. Since the number of places is limited\, please register below to participate in this session. \n\n\n\n\n\n\n\nRegister\n\n\n\n\n\n\n\nUsing cutting-edge\, superresolution imaging technology to visualize cellular activity at the nano-scale\, Lippincott-Schwartz lab has redefined how we look at protein dynamics in the cell. When describing her mentorship philosophy\, Jennifer comments that she encourages her group members to develop their own projects. It is only when a colleague feels that he or she “owns” the project that real dedication\, determination\, and creativity emerge. In developing projects\, she considers it is important to build on the strengths and interests of students and postdocs\, rather than focusing exclusively on a group leader’s specific interests at the time. \n\n\n\nThe annual lecture series is set up in the recognition of the development of electron microscopy and will be delivered by eminent scientists in the field of structural biology and molecular visualisation. The event is open to anyone. The main lecture will take place at 4.00pm in the Biomedicum Lecture Theatre. \n\n\n\nContact \n\n\n\nAlexey Amunts\, amunts@scilifelab.se
URL:https://www.scilifelab.se/event/career-path-discussions-with-jennifer-lippincott-schwartz/
LOCATION:Air&Fire\, SciLifeLab Stockholm\, Tomtebodavägen 23A\, Solna\, Sweden
CATEGORIES:Event
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20211108T151500
DTEND;TZID=Europe/Stockholm:20211108T163000
DTSTAMP:20260403T213301
CREATED:20211005T080424Z
LAST-MODIFIED:20211005T080541Z
UID:10000460-1636384500-1636389000@www.scilifelab.se
SUMMARY:The Svedberg seminar series: Ass. Prof. Maria Kasper
DESCRIPTION:Karolinska Institutet\, Department of Cell and Molecular Biology\, Sweden \n\n\n\nLINK TO SEMINAR   \n\n\n\n\n\n\n\n\n\nMaria Kasper is Associate Professor at the Karolinska Institutet in Stockholm\, Department of Cell and Molecular Biology. She received her PhD at the University of Salzburg in genetics\, with the majors in human genetics and molecular tumor biology. She came to Sweden in 2007\, where she spent a fruitful postdoctoral time in Rune Toftgårds lab\, and in 2013 she started her own lab focusing on skin\, stem cell biology and single-cell RNA sequencing. In 2016\, her lab pioneered the use of single-cell transcriptomics in the organ skin and has overall contributed with important work in skin biology and regenerative medicine. Maria has received a number of national recognitions such as the Framtidens Forskningsledare from SSF\, Ragnar Söderberg Fellow in Medicine and the CIMED young investigator award\, as well as the prestigious international LEO Foundation Gold Award for outstanding skin research. Since 2020\, she also coordinates together with Fiona Watt the Human Cell Atlas bionetwork for the organ skin. \n\n\n\nDecoding the molecular anatomy of skin\n\n\n\nSkin architecture and its function are determined by a rich variety of epithelial\, mesenchymal and immune cells that together orchestrate skin homeostasis\, including cyclical hair growth and barrier function. Previously\, my lab generated a comprehensive molecular and spatial atlas of epithelial and stromal cells during hair growth and rest. These studies revealed underlying molecular programs during progenitor-cell commitment and lineage differentiation\, as well as spatiotemporal fibroblast heterogeneity and potential epithelial-stromal interactions. The importance of cell-type specific signaling during homeostasis\, and the unrecognized potential of cell-type restricted signaling-changes were exemplified by our recent discovery of how to induce new hair follicles in adult mouse skin by modulating a single signaling pathway. Building on the molecular knowledge and computational skills gained\, our ongoing work uncovers new insights in the molecular orchestration of embryonic hair follicle development\, as well as the coordination of adult skin stem cell differentiation by tissue resident immune cells.Host: Gabriella Lindgren\, SLU
URL:https://www.scilifelab.se/event/the-svedberg-seminar-series-ass-prof-maria-kasper/
LOCATION:Online event via Zoom
CATEGORIES:Event
ORGANIZER;CN="The Svedberg Seminar Series":MAILTO:thesvedberg@scilifelab.uu.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20211108T160000
DTEND;TZID=Europe/Stockholm:20211108T170000
DTSTAMP:20260403T213301
CREATED:20210609T090256Z
LAST-MODIFIED:20210826T100440Z
UID:10000399-1636387200-1636390800@www.scilifelab.se
SUMMARY:Annual lecture in structural biology by Jennifer Lippincott-Schwartz
DESCRIPTION:Jennifer Lippincott-Schwartz from the Howard Hughes Medical Institute will give the lecture entitled ‘Emerging Imaging Technologies to Study Cell Architecture\, Dynamics\, and Function’ on November 8\, 2021 at 4.00pm in the Biomedicum lecture theatre. Using cutting-edge\, superresolution imaging technology to visualize cellular activity at the nano-scale\, Lippincott-Schwartz lab has redefined how we look at protein dynamics in the cell. \n\n\n\nThe annual lecture series is set up in the recognition of the development of electron microscopy and will be delivered by eminent scientists in the field of structural biology and molecular visualisation. The event is open to anyone. A holder of the lectureship will particularly spend time with students and postdocs. Therefore\, Jennifer will also give an account of her career path and discuss with students and postdocs at 09.30am in the SciLifeLab Air&Fire auditorium. \n\n\n\nAbout Jennifer Lippincott-Schwartz \n\n\n\nResearch in Lippincott-Schwartz lab is aimed at developing live cell imaging to elucidate the dynamics inside eukaryotic cells. She pioneered photobleaching and photoactivation techniques which allow investigation of subcellular localization\, turnover and trafficking of important cellular proteins related to membrane compartmentalization. Her work on photoactivatable GFP led to the development of one of the first super-resolution imaging technologies\, photoactivation localization microscopy. Jennifer then used her methods to assess organelles dynamics and interactions revealing a novel picture of how the peripheral endoplasmic reticulum is structured. In addition\, the Golgi apparatus is central to Jennifer’s studies\, where her team demonstrated a novel pathway of enzymes recycling important for the organelle’s biogenesis and maintenance. Together\, the obtained findings have provided insights into how genetic diseases affect proteins that help shape the endoplasmic reticulum. \n\n\n\nIn 2016\, Lippincott-Schwartz initiated the Neuronal Cell Biology Program at Janelia. She is Fellow of the American Academy of Arts and Sciences Fellow\, and also Honorary Fellow of the Royal Microscopical Society.  \n\n\n\nBackground information \n\n\n\nThe annual lecture in structural biology is named in honour of Fritiof Sjöstrand\, who pioneered the electron microscopy in Sweden. In the early 1950’s he developed an advanced microtome for thin sectioning\, and by applying it for structural analysis of mitochondria produced a major breakthrough with the determination of the double membrane system. He then engineered a next generation of microtomes using electrical heating of the specimen to advance it toward the knife\, and the instrument became known as the ‘‘Sjöstrand Ultramicrotome”. In 1959\, Fritiof Sjöstrand moved to UCLA\, where his research focused on mitochondrial membranes and retinal synapses. Fritiof Sjöstrand founded and was Editor in Chief of the Journal of Structural Biology for 33 years. Lectures in the previous years were given by Venki Ramakrishnan and Jennifer Doudna. \n\n\n\nContact \n\n\n\nAlexey Amunts\, amunts@scilifelab.se
URL:https://www.scilifelab.se/event/emerging-imaging-technologies-to-study-cell-architecture-dynamics-and-function/
LOCATION:Biomedicum\, Solnavägen 9\, Solna
CATEGORIES:Event
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20211109T100000
DTEND;TZID=Europe/Stockholm:20211109T110000
DTSTAMP:20260403T213301
CREATED:20211102T153126Z
LAST-MODIFIED:20211102T153315Z
UID:10000478-1636452000-1636455600@www.scilifelab.se
SUMMARY:The curious case of a leak channel that never wants to be open
DESCRIPTION:Stephan Pless\, PhD \n\n\n\nProfessor of Molecular and Cellular PharmacologyUniversity of Copenhagen\, Denmark \n\n\n\nThe Pless lab is interested in the molecular function and pharmacology of ion channels. These complex membrane proteins regulate cellular excitability by controlling the flux of ions across cell membranes in response to a diverse set of stimuli. Their dysfunction is associated with numerous diseases\, resulting in an ever-increasing demand for new drugs targeting these fascinating molecules. \n\n\n\n\n\n\n\nDownload
URL:https://www.scilifelab.se/event/the-curious-case-of-a-leak-channel-that-never-wants-to-be-open/
LOCATION:Air&Fire\, SciLifeLab Stockholm\, Tomtebodavägen 23A\, Solna\, Sweden
CATEGORIES:Event
ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2021/11/Skärmavbild-2021-11-02-kl.-16.27.31.png
ORGANIZER;CN="Molecular Biophysics Stockholm":MAILTO:join-mbp@scilifelab.se.
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20211109T150000
DTEND;TZID=Europe/Stockholm:20211109T160000
DTSTAMP:20260403T213301
CREATED:20211101T085537Z
LAST-MODIFIED:20211101T085648Z
UID:10000476-1636470000-1636473600@www.scilifelab.se
SUMMARY:Insights into EMBO’s Fellowship Programme
DESCRIPTION:Kelly Sheehan-Rooney\, Head of the Fellowship Programme at EMBO\, will give an overview of the eligibility and evaluation criteria of EMBO’s Postdoctoral Fellowships\, Scientific Exchange Grants\, and the New Venture Fellowships. She will also give some top tips for grant writing\, and an insight into her career move from academic research to international research development. \n\n\n\nKelly Sheehan-Rooney is Head of the Fellowship Programme at EMBO. She obtained her PhD in Developmental Biology from the University of Manchester\, UK\, before carrying out a three-year postdoctoral position at the University of Texas in Austin\, USA. Now with 10 years’ experience in international research development\, Kelly has worked with thousands of scientists across the world; supporting them in their various careers\, building collaborative networks\, and fostering a research environment where scientists can achieve their best work. \n\n\n\nResearchers in all stages of their career are welcome to attend and could find the talk useful. The fellowships are a great opportunity for early-stage researchers as well as for group leaders to further their research interests and consider new avenues to expand into high quality research ideas. \n\n\n\nMeeting Flyer
URL:https://www.scilifelab.se/event/insights-into-embos-fellowship-programme/
LOCATION:Online event via Zoom
CATEGORIES:Event
ORGANIZER;CN="SciLifeLab Solna PhD & Postdoc Council":MAILTO:phd-council@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20211110T140000
DTEND;TZID=Europe/Stockholm:20211110T150000
DTSTAMP:20260403T213301
CREATED:20211014T151000Z
LAST-MODIFIED:20211020T130718Z
UID:10000466-1636552800-1636556400@www.scilifelab.se
SUMMARY:[Drug Discovery Seminar] How protein degradation led to faculty entrepreneurship at Yale: A personal Perspective
DESCRIPTION:SciLifeLab Drug Discovery Seminars\, hosted by the DDD platform\, is a series of educational lectures about recent developments\, technologies\, and trends in drug discovery and development that aims to enlighten\, and spark a discussion\, within the Swedish drug discovery community. \n\n\n\nCraig Crews\n\n\n\n\n\n\n\n \n\n\n\nJohn C. Malone Professor of Molecular\, Cellular\, and Developmental Biology and Professor of Chemistry\, of Pharmacology\, and of Management; Executive Dirictor\, Yale Center for Molecular Discovery\, Yale University \n\n\n\nAbstract \n\n\n\nProf. Crews is the 2021 recipient of the Scheele prize from the Swedish Pharmaceutical Society for his seminal work on protein degradation. In this talk Prof. Crews will discuss his efforts to translate research from his lab into new biopharma ventures.  To date\, these entrepreneurial  efforts have resulted in a FDA approved drug (Kyprolis) and a new therapeutic modality (PROTACs).  While each of his four companies has been launched based on different science\, they have all followed a similar business model and Prof. Crews will discuss efforts at Yale to ’systematize’ faculty entrepreneurism via a core ‘biotech accelerator’ facility. \n\n\n\nregistration\n\n\n\nBiography \n\n\n\nCrews is the John C. Malone Professor of Molecular\, Cellular and Developmental Biology and holds joint appointments in the departments of Chemistry and Pharmacology at Yale University. He graduated from the U.Virginia with a B.A. in Chemistry and received his Ph.D. from Harvard University in Biochemistry. Dr. Crews has a foothold in both the academic and biotech arenas; on the faculty at Yale since 1995\, his laboratory has pioneered the use of small molecules to control intracellular protein levels.  \n\n\n\nIn 2003\, he co-founded Proteolix\, Inc.\, whose proteasome inhibitor\, Kyprolis™ received FDA approval for the treatment of multiple myeloma. Since Proteolix’s purchase by Onyx Pharmaceuticals in 2009\, Dr. Crews has focused on a new drug development technology\, which served as the founding intellectual property for his latest New Haven-based biotech venture\, Arvinas\, Inc.  \n\n\n\nCurrently\, Dr. Crews serves on several editorial boards and was Editor of Cell Chemical Biology (2008-2018). In addition\, he has received numerous awards and honors\, including the 2013 CURE Entrepreneur of the Year Award\, 2014 Ehrlich Award for Medicinal Chemistry\, 2015 Yale Cancer Center Translational Research Prize\, a NIH R35 Outstanding Investigator Award (2015)\, the AACR Award for Chemistry in Cancer Research (2017)\, Khorana Prize from the Royal Society of Chemistry (2018)\, Pierre Fabre Award for Therapeutic Innovation (2018)\, the Pharmacia-ASPET Award for Experimental Therapeutics (2019)\, the Heinrich Wieland Prize (2020) and the Scheele Prize (2021). In 2019\, he was named an American Cancer Society Professor.
URL:https://www.scilifelab.se/event/drug-discovery-seminar-faculty-entrepreneurship-at-yale-a-personal-perspective/
LOCATION:Air&Fire\, SciLifeLab Stockholm\, Tomtebodavägen 23A\, Solna\, Sweden
CATEGORIES:Event
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20211111T130000
DTEND;TZID=Europe/Stockholm:20211111T140000
DTSTAMP:20260403T213301
CREATED:20210903T122243Z
LAST-MODIFIED:20211101T124236Z
UID:10000432-1636635600-1636639200@www.scilifelab.se
SUMMARY:Campus Solna Seminar Series: Michael Hawgood and Akshay Sridhar
DESCRIPTION:Welcome to join the Campus Solna Seminar Series – an  initiative to promote the fantastic science ongoing at Campus Solna and hopefully forge more internal communication and collaboration between within Campus Solna. The format consists of two 15 min talks (One speaker from the Alpha-building and one from the Gamma-building respectively)\, with an additional 5 min of questions. Presentation of ongoing (unpublished) projects is strongly encouraged. \n\n\n\nThe seminars are held Thursdays 13:00-13:50 and following current regulations\, they will be broadcast via zoom. \n\n\n\n \n\n\n\nThis week\n\n\n\nExploring DNA Replication Using Super Resolution and Expansion MicroscopyMichael Hawgood (Jiri Bartek\, alpha 5)  \n\n\n\n \n\n\n\nLipid modulation of membrane protein functionAkshay Sridhar (Lucie Delemotte/Erik Lindahl) \n\n\n\nRegistration\n\n\n\nRegister to receive the zoom-link. The same zoom link applies for all Campus Solna Seminar Series\, i.e. only one registration is necessary.
URL:https://www.scilifelab.se/event/campus-solna-seminar-series-michael-hawgood-and-akshay-sridhar/
CATEGORIES:Community
ORGANIZER;CN="SciLifeLab Solna PhD & Postdoc Council":MAILTO:phd-council@scilifelab.se
END:VEVENT
END:VCALENDAR