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X-WR-CALDESC:Events for SciLifeLab
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BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220914T140000
DTEND;TZID=Europe/Stockholm:20220914T150000
DTSTAMP:20260404T102931
CREATED:20220905T092055Z
LAST-MODIFIED:20220906T122905Z
UID:10000667-1663164000-1663167600@www.scilifelab.se
SUMMARY:Systems Analysis of Human Metabolism for Identification of Drug Targets and Biomarkers
DESCRIPTION:Systems Analysis of Human Metabolism for Identification of Drug Targets and Biomarkers \n\n\n\nWelcome to a lecture by Professor Jens Nielsen\, \n\n\n\nBioinnovation Institute\, Copenhagen\, Denmark. \n\n\n\n \n\n\n\n \n\n\n\n\n\n\n\nJens Nielsen is MSc in Chemical Engineering and PhD (1989) in Biochemical Engineering from the Danish Technical University (DTU). Fulbright visiting professor at MIT in 1995-1996. Professor at DTU in 1998. In 2008 he was recruited as Professor to Chalmers University of Technology\, Sweden. In 2015 he was founding Head of the Department of Biology and Biological Engineering\, which now encompass more than 200 people. Jens Nielsen was also a co-founder of the Novo Nordisk Foundation Center for Biosustainability that now have more than 300 people affiliated\, for which he served as CSO 2013-2018. From 2019 CEO of the BioInnovation Institute in Denmark\, which is a new institute financed by USD0.5B that fosters translational research and support new spin-out companies in life sciences. He has trained more than 280 scientists in his research group and published >850 publications that have been cited more than 98\,000 times (current H-factor 142). Inventor of >50 patents and founder of seven biotech companies. Has received numerous awards\, including the ENI Award\, the Eric and Sheila Samson Prime Minister Prize for Transportation Fuels\, the Novozymes Prize\, and the Gold Medal from the Royal Swedish Academy of Engineering Sciences. Member of 12 academies\, including NAS\, NAE\, Chinese Academy of Engineering\, EMBO and Royal Swedish Academy of Science. He will discuss the challenges of using systems medicine for advancing the development of personalized and precision medicine\, and it will be illustrated how the concept of genome-scale metabolic models can be used for integrative analysis of big data with the objective of identifying novel biomarkers that are foundational for personalized and precision medicine. \n\n\n\nThis keynote lecture is part of the FEBS Advanced Course – Exploring the Human Proteome
URL:https://www.scilifelab.se/event/systems-analysis-of-human-metabolism-for-identification-of-drug-targets-and-biomarkers/
LOCATION:Air&Fire\, SciLifeLab Stockholm\, Tomtebodavägen 23A\, Solna\, Sweden
CATEGORIES:Event
ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2022/04/FEBS-Advanced-course.png
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220915T103000
DTEND;TZID=Europe/Stockholm:20220916T133000
DTSTAMP:20260404T102931
CREATED:20220620T071511Z
LAST-MODIFIED:20220831T142048Z
UID:10000628-1663237800-1663335000@www.scilifelab.se
SUMMARY:SciLifeLab Genomics platform retreat
DESCRIPTION:Very welcome to this event for the Genomics platform. We look forward to fun days with time to interact with new and old colleagues\, discuss science and our operation\, and get the latest information on the development of SciLifeLab and our platform. The meeting will take place at beautiful Haga Slott\, just outside of Enköping. \n\n\n\nThere will be buses that leave from BMC\, Uppsala and SciLifeLab Campus Solna at 09:00 on Sept. 15\, and return from Haga Slott at 13:30 on Sept. 16. \n\n\n\nRegistration has closed. \n\n\n\n\n\n\n\nFor questions about the program and participation\, contact magnus.lundgren@scilifelab.uu.se \n\n\n\nFor information about the venue\, see https://hagaslott.se/en/haga-castle/ \n\n\n\n\n\n\n\nProgram\n\n\n\nSeptember 1509:00 Buses depart from SciLifeLab Solna and BMC (Uppsala)10:00 Arrival Haga Slott and coffee10:30 The SciLifeLab Genomics platform: status\, plans and visions11:15 Scientific keynote “DeepTime genomics”\, Love Dalén\, Professor at Department of Zoology\, Stockholm University12:00 Lunch13:00 SciLifeLab national nodes: opportunities for synergies14:00 Check-in14:30 Coffee15:00 Social activity\, bring clothes and shoes suitable for being outside16:30 Free time for spa\, gym\, sauna swimming\, etc.18:00 Drinks reception19:00 DinnerSeptember 1609:00 Introduction to group discussion09:15 Group discussions\, including coffee break11:00 Summary of group discussions and meeting wrap-up12:00 Lunch13:30 Buses depart for SciLifeLab Solna and BMC (Uppsala)
URL:https://www.scilifelab.se/event/scilifelab-genomics-platform-retreat/
LOCATION:Haga slott\, Haga slott\, Enköping\, 745 93\, Sweden
CATEGORIES:Community
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220915T120000
DTEND;TZID=Europe/Stockholm:20220915T130000
DTSTAMP:20260404T102931
CREATED:20220818T145429Z
LAST-MODIFIED:20220907T191107Z
UID:10000648-1663243200-1663246800@www.scilifelab.se
SUMMARY:Campus Solna Seminar Series: Christoffer Mattsson Langseth
DESCRIPTION:Welcome to join the Campus Solna Seminar Series – an  initiative to promote the fantastic science ongoing at Campus Solna and hopefully forge more internal communication and collaboration between within Campus Solna. The format consists of two 15 min talks (One speaker from the Alpha-building and one from the Gamma-building respectively)\, with an additional 5 min of questions. Presentation of ongoing (unpublished) projects is strongly encouraged. \n\n\n\nThe seminars are held Thursdays 12:00-13:00. You can bring your lunch to the seminar. \n\n\n\nThis week:\n\n\n\n\n\n\nTBD\n\n\n\nTBD \n\n\n\n\n\nChristoffer Mattsson Langseth\n\n\n\nMats Nilsson – gamma 4 \n\n\n\nSpatial mapping of oligodendroglial\, neuronal and immune cell-type heterogeneity in a model of multiple sclerosis \n\n\n\n\n\n\nThis seminar series is organized by the PhD & Postdoc Council. For more information about the Council and other events check our page.
URL:https://www.scilifelab.se/event/campus-solna-seminar-series-sep-15/
LOCATION:Milkyway SciLifeLab Solna\, Tomtebodavägen 23\, Solna
CATEGORIES:Community
ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2022/08/logo_PhD_Postdoc_Council.png
ORGANIZER;CN="SciLifeLab Solna PhD & Postdoc Council":MAILTO:phd-council@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220915T180000
DTEND;TZID=Europe/Stockholm:20220915T190000
DTSTAMP:20260404T102931
CREATED:20220906T122422Z
LAST-MODIFIED:20220906T122503Z
UID:10000672-1663264800-1663268400@www.scilifelab.se
SUMMARY:Molecular analysis of human diversity and its impact on drug discovery using iPS cells
DESCRIPTION:Molecular analysis of human diversity and its impact on drug discovery using iPS cells \n\n\n\n \n\n\n\nWelcome to a lecture by Professor Angus I. Lamond\, \n\n\n\nUniversity of Dundee\, UK. \n\n\n\n16.00-17.00 Thursday September 15 \n\n\n\nAir & Fire (Gamma 2) or via zoom https://kth-se.zoom.us/s/69393882589 \n\n\n\n\n\n\n\nProfessor Lamond has over thirty years of experience as a Principal Investigator\, studying molecular mechanisms regulating gene expression and pre-mRNA splicing. This includes major contributions to the biochemical analysis of the human splicing machinery and to the study of functional compartments and subnuclear bodies in mammalian cells. The AIL group have developed new methods and technical approaches in these fields that have advanced mechanistic studies at the molecular and cellular levels\, spanning biochemical\, microscopy and MS-based proteomics technologies. During the past fifteen years\, the AIL laboratory has developed and applied state of the art mass spectrometry-based proteomic approaches in research projects studying molecular mechanisms regulating gene expression in both human cells and model organisms. This includes\, specifically\, integrated poly-omics analyses of human induced pluripotent stem cells (hiPSCs)\, derived from both healthy donors and patient cohorts with inherited disorders. Other studies have focused on proteome dynamics in the context of biological response mechanisms and ongoing studies identifying and characterizing small molecule modulators of alternative splicing and analysis of how splicing mechanisms affect cell proteomes\, protein isoform expression and resulting cell phenotypes. He will describe the progress in using both quantitative\, MS-based proteomics and high throughput imaging technologies to characterize libraries of human induced pluripotent stem cell (iPSC) lines\, derived from hundreds of different donors\, and show how comparisons of such iPSC lines can provide a novel approach for assessing mechanisms of variable drug response and help to deliver more safe new drugs that cater for the needs of diverse human populations. \n\n\n\nThis keynote lecture is part of the FEBS Advanced Course – Exploring the Human Proteome
URL:https://www.scilifelab.se/event/molecular-analysis-of-human-diversity-and-its-impact-on-drug-discovery-using-ips-cells/
LOCATION:Air&Fire\, SciLifeLab Stockholm\, Tomtebodavägen 23A\, Solna\, Sweden
CATEGORIES:Event
ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2022/04/FEBS-Advanced-course.png
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220919T100000
DTEND;TZID=Europe/Stockholm:20220919T110000
DTSTAMP:20260404T102931
CREATED:20220823T174147Z
LAST-MODIFIED:20220823T174148Z
UID:10000652-1663581600-1663585200@www.scilifelab.se
SUMMARY:Ribosome heterogeneity and specialization during temperature acclimation in plants
DESCRIPTION:Seidel\, Max Planck Institute of Molecular Plant Physiology\, Potsdam\, GermanyDate: Monday 19 September 2022Time: 10.00 – 11.00Location: Gamma“Ribosome heterogeneity and specialization during temperature acclimation in plants”Host: Alexey Amunts
URL:https://www.scilifelab.se/event/ribosome-heterogeneity-and-specialization-during-temperature-acclimation-in-plants/
LOCATION:Becquerel\, SciLifeLab\, Tomtebodavägen 23\, Solna
CATEGORIES:Community
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220921T110000
DTEND;TZID=Europe/Stockholm:20220922T120000
DTSTAMP:20260404T102931
CREATED:20220825T104709Z
LAST-MODIFIED:20220902T094832Z
UID:10000653-1663758000-1663848000@www.scilifelab.se
SUMMARY:AIDA-SciLifeLab days
DESCRIPTION:Welcome to AIDA-SciLifeLab days in Uppsala\, September 21-22\n\n\n\nAnalytic Imaging Diagnostics Arena\, AIDA\, is a national arena for research and innovation around artificial intelligence\, AI\, for medical image analysis. Here\, academia\, healthcare and industry meet to translate technological advances in AI technology into patient benefits in the form of clinically useful tools. AIDA is an initiative within the Strategic Innovation Program Medtech4Health\, a joint venture of VINNOVA\, Formas and the Energy Agency. AIDA offers funding\, technical infrastructure and a broad expert community. The community meets in regular intervals at AIDA-days; seminar days with current medical imaging themes. \n\n\n\n\n\n\n\nThe AIDA days are on tour\, our first stop was Stockholm KTH\, and this time we are happy to visit Uppsala. SciLifeLab and Carolina Wählby are kindly hosting the event. We will now have the great opportunity to get an insight into the work on AI in medical imaging in Uppsala – focus areas and ongoing projects. We can look forward to presentations in quantitative microscopy\, image classification\, image registration and the European Big Picture project (a central repository for digital pathology slides). In addition\, we will listen to two final AIDA project presentations by the research groups of Robin Strand – MRI guided real-time adaptive radiotherapy and Joel Kullberg – Advanced Body Composition Analysis in SCAPIS. Each AIDAday will end with a study visit: at the radiology department (MR-Linac) and the pathology department\, respectively.  \n\n\n\n\n\n\n\nRegistration\n\n\n\n\n\n\n\nProgram September 21\n\n\n\nProgram September 22\n\n\n\n\n\n\n\nShort Program\n\n\n\n \n\n\n\n\n\nSEPT. 21:Venue: Nya Ångström\, lecture hall 101136 B (floor1)11:00Internal meeting for AIDA members only 12:00Lunch (recommendation “Rullan”\, Nya Ångström)13:00Official program17:00End of program19:00After Work at Stationen (optional)SEPT. 22:Venue: SciLifeLab Navet\, Trippelrummet\, BMC\, entrance C1109:00Official program12:00End of program\n\n\n\n\n\n\n\n\nLunch and AW at your own expense. \n\n\n\n\n\n\nFor those who are not able to attend the AIDAdays physically\, a Zoom link will be distributed to registered participants prior to the meeting. Please register here! \n\n\n\nMost Welcome!
URL:https://www.scilifelab.se/event/aida-scilifelab-days/
CATEGORIES:Event
ATTACH;FMTTYPE=image/jpeg:https://www.scilifelab.se/wp-content/uploads/2022/08/image001.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220922T120000
DTEND;TZID=Europe/Stockholm:20220922T130000
DTSTAMP:20260404T102931
CREATED:20220818T153954Z
LAST-MODIFIED:20220912T093259Z
UID:10000649-1663848000-1663851600@www.scilifelab.se
SUMMARY:Campus Solna Seminar Series: Yuying Cheng and Osheen Sharma
DESCRIPTION:Welcome to join the Campus Solna Seminar Series – an  initiative to promote the fantastic science ongoing at Campus Solna and hopefully forge more internal communication and collaboration between within Campus Solna. The format consists of two 15 min talks (One speaker from the Alpha-building and one from the Gamma-building respectively)\, with an additional 5 min of questions. Presentation of ongoing (unpublished) projects is strongly encouraged. \n\n\n\nThe seminars are held Thursdays 12:00-13:00. You can bring your lunch to the seminar. \n\n\n\nThis week:\n\n\n\n\n\n\nYuying Cheng\n\n\n\nSimon Elsässer – alpha 4 \n\n\n\nDefining histone variant H3.3 dynamics using pulse-chase experiment and computational modeling \n\n\n\n\n\nOsheen Sharma\n\n\n\nBrinton Seashore-Ludlow – alpha 4 \n\n\n\nImage based Drug Mechanism of Action Clustering using Deep Neural Networks \n\n\n\n\n\n\nThis seminar series is organized by the PhD & Postdoc Council. For more information about the Council and other events check our page.
URL:https://www.scilifelab.se/event/campus-solna-seminar-series-sep-22/
LOCATION:Air&Fire\, SciLifeLab Stockholm\, Tomtebodavägen 23A\, Solna\, Sweden
CATEGORIES:Community
ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2022/08/logo_PhD_Postdoc_Council.png
ORGANIZER;CN="SciLifeLab Solna PhD & Postdoc Council":MAILTO:phd-council@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220926T080000
DTEND;TZID=Europe/Stockholm:20220930T170000
DTSTAMP:20260404T102931
CREATED:20220523T075158Z
LAST-MODIFIED:20220523T100120Z
UID:10000614-1664179200-1664557200@www.scilifelab.se
SUMMARY:Introduction to bioinformatics using NGS data
DESCRIPTION:This is a national workshop open to PhD students\, post-docs\, and other researchers affiliated to Swedish academia and healthcare. The workshop is organised by the National Bioinformatics Infrastructure Sweden (NBIS) and National Genomics Infrastructure (NGI). \n\n\n\nThis intense one-week workshop provides an introduction to the analysis of next generation sequencing data. Lectures on the theory of concepts will be paired with practical computational exercises in the Linux environment. The practical exercises will focus on data from the Illumina platform\, but we will discuss other sequencing platforms and the advantages and challenges to using their data during the lectures. \n\n\n\nNBIS training events do not provide any formal university credits. Attendees with full attendance and completion of tasks will be issued a certificate of participation indicating topics covered and duration of the workshop. For more detailed information about workshop syllabus\, learning outcomes and entry requirements\, please visit the workshop website. \n\n\n\nImportant dates\n\n\n\nWorkshop: 26-Sep-2022 – 30-Sep-2022 \n\n\n\nApplication opens: 23-May-2022 \n\n\n\nApplication closes: 19-Aug-2022 \n\n\n\nConfirmation to accepted students: 26-Aug-2022 \n\n\n\nCourse fee\n\n\n\nThis on-site training event costs 2000 SEK invoiced to the participant’s organisation. If you accept a position and do not participate (no-show) you will still be invoiced 2000 SEK. Please note that NBIS cannot invoice individuals. \n\n\n\nContact\n\n\n\nnbis.se \n\n\n\nMalin Larsson\, Martin Dahlö\, Roy Francis \n\n\n\n\n\n\n\n\nWorkshop Website\n\n\n\nApplication
URL:https://www.scilifelab.se/event/introduction-to-bioinformatics-using-ngs-data/
LOCATION:Navet\, SciLifeLab Uppsala\, SciLifeLab Uppsala\, BMC C11\, Husargatan 3\, Uppsala\, 75237\, Sweden
CATEGORIES:Course
ORGANIZER;CN="NBIS - National Bioinformatics Infrastructure Sweden":MAILTO:education@nbis.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220926T090000
DTEND;TZID=Europe/Stockholm:20220926T100000
DTSTAMP:20260404T102931
CREATED:20220923T132853Z
LAST-MODIFIED:20220923T132926Z
UID:10000689-1664182800-1664186400@www.scilifelab.se
SUMMARY:Multiscale Modelling of Cancer Cell Motility and Tumour Evolution
DESCRIPTION:Paul Bates\, Cricks institute\, UK\n\n\n\n \n\n\n\n \n\n\n\n \n\n\n\nMultiscale Modelling of Cancer Cell Motility and Tumour Evolution \n\n\n\nSince Inhibiting metastasis is as crucial as minimising tumour growth for efficient treatment of cancer\, we constructed a multiscale model of cancer cell motility\, with our primary focus being on amoeboid type cell motility of metastasising tumour cells in the extracellular matrix (ECM).  Our model covered a wide parameter space and provided a deeper understanding of the conditions governing the motility of the cell at multiscale levels. Both the extracellular conditions (e.g. ECM density) and intrinsic cell properties (e.g. relative distribution of contractile and expanding regions of the cell membrane) were investigated.  The aim was to identify the combination of intrinsic properties metastasising cells are more likely to use under different extracellular conditions. After extensive benchmarking of the computational model using in vitro data\, we were able to predict cancer cell motility in vivo and under a number of different combinations of motility inhibitory\, such as key kinase inhibitors. We have also developed multiscale computer models to investigate how tumours evolve based upon Intra-tumour genetic heterogeneity (ITH)\, which fuels ongoing clonal evolution. Despite clarified clonal structure and acknowledged role of ITH in disease progression within our recent tumour study\, investigating clear-cell renal cell carcinomas (ccRCCs)\, there lacks characterisation of ongoing evolution that may inform future risk. By the combination of computer modelling and experimental analysis\, we investigated spatial features of narrow-scale clone diversity (microdiversity) and parallel evolution on the impact of spatial tumour growth. We observed frequent microdiversity hotspots and parallel evolution near the tumour margin and uncovered a scaling relationship between the area spanned by a genomic alteration and the number of subclones within that area\, in simulated tumours of 66 ccRCCs. Furthermore\, in-silico time-course studies showed that different modes of spatial growth caused varying extents and tempos of subclonal diversification.  Interestingly\, evolutionary trajectories were often predictable early\, suggesting that spatially resolved sampling combined with sequencing may enable identification of evolutionary potential in early-stage tumours.
URL:https://www.scilifelab.se/event/multiscale-modelling-of-cancer-cell-motility-and-tumour-evolution/
LOCATION:Air&Fire\, SciLifeLab Stockholm\, Tomtebodavägen 23A\, Solna\, Sweden
CATEGORIES:Event
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220927T100000
DTEND;TZID=Europe/Stockholm:20220927T113000
DTSTAMP:20260404T102931
CREATED:20220919T131401Z
LAST-MODIFIED:20220920T053525Z
UID:10000682-1664272800-1664278200@www.scilifelab.se
SUMMARY:Next-Generation Cytogenomics with Optical Genome Mapping
DESCRIPTION:Clinical Genomics Stockholm has acquired a Saphyr optical mapper from Bionano Genomics and it will be available as a national service. We would like to provide more information on the instrument and applications by giving a seminar. \n\n\n\nClick here to sign up\n\n\n\nFlyer\n\n\n\nFlyer_symposium_stockholm-1Download
URL:https://www.scilifelab.se/event/next-generation-cytogenomics-with-optical-genome-mapping/
LOCATION:Wangari\, Widerströmska building\,\, Tomtebodavägen 18\, Solna\, Sweden
CATEGORIES:Event
ORGANIZER;CN="Clinical Genomics Platform":MAILTO:marcela.davila@gu.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220928T090000
DTEND;TZID=Europe/Stockholm:20220928T150000
DTSTAMP:20260404T102931
CREATED:20220629T154628Z
LAST-MODIFIED:20220715T122018Z
UID:10000638-1664355600-1664377200@www.scilifelab.se
SUMMARY:SciLifeLab symposium in superresolution microscopy
DESCRIPTION:We cordially welcome you to a symposium teaching applications of superresolution fluorescence microscopy from world leading experts in the field.  \n\n\n\nRegistration to hans.blom@scilifelab.se \n\n\n\n \n\n\n\n\n\n\n\nProgram\n\n\n\n09:00OpeningDr Hans Blom – SciLifeLab\, Campus Solna09:05Superresolution microbiology using PALMProf Ulrike Endesfelder – University of Bonn\, Germany09:50The axonal architecture at the nanoscale revealed by STORMDr Christophe Leterrier – CNRS – Aix Marseille University\, FranceCoffee break11:00Characterization of organelle dynamics with live-cell STEDDr Giovanna Coceano – SciLifeLab\, Campus Solna11:45MINFLUX in practiceDr Daniel Jans – University Medical Center Göttingen\, GermanyPhD-students/Postdocs may also sign up for one-on-one project discussions with the experts (1:45 – 3:00 pm)
URL:https://www.scilifelab.se/event/scilifelab-symposium-in-superresolution-microscopy/
LOCATION:Air&Fire\, SciLifeLab Stockholm\, Tomtebodavägen 23A\, Solna\, Sweden
CATEGORIES:Event
ORGANIZER;CN="Advanced Light Microscopy Unit":MAILTO:stewen@kth.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220929T120000
DTEND;TZID=Europe/Stockholm:20220929T130000
DTSTAMP:20260404T102931
CREATED:20220823T124133Z
LAST-MODIFIED:20220916T080422Z
UID:10000650-1664452800-1664456400@www.scilifelab.se
SUMMARY:Campus Solna Seminar Series: Koeun Shong and Hanna Van Ooijen
DESCRIPTION:Welcome to join the Campus Solna Seminar Series – an  initiative to promote the fantastic science ongoing at Campus Solna and hopefully forge more internal communication and collaboration between within Campus Solna. The format consists of two 15 min talks (One speaker from the Alpha-building and one from the Gamma-building respectively)\, with an additional 5 min of questions. Presentation of ongoing (unpublished) projects is strongly encouraged. \n\n\n\nThe seminars are held Thursdays 12:00-13:00. You can bring your lunch to the seminar. \n\n\n\nThis week:\n\n\n\n\n\n\nKoeun Shong\n\n\n\nAdil Mardinoglu – alpha 6 \n\n\n\nNovel treatment for sarcopenia in vitro model by activating pyruvate kinase \n\n\n\n\n\nHanna Van Ooijen\n\n\n\nBjörn Önfelt – gamma 3 \n\n\n\nA thermoplastic microwell chip for 2D and 3D microscopy-based cellular assays \n\n\n\n\n\n\nThis seminar series is organized by the PhD & Postdoc Council. For more information about the Council and other events check our page.
URL:https://www.scilifelab.se/event/campus-solna-seminar-series-sep-29/
LOCATION:Air&Fire\, SciLifeLab Stockholm\, Tomtebodavägen 23A\, Solna\, Sweden
CATEGORIES:Community
ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2022/08/logo_PhD_Postdoc_Council.png
ORGANIZER;CN="SciLifeLab Solna PhD & Postdoc Council":MAILTO:phd-council@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220929T140000
DTEND;TZID=Europe/Stockholm:20220929T150000
DTSTAMP:20260404T102931
CREATED:20220913T160723Z
LAST-MODIFIED:20220913T161924Z
UID:10000681-1664460000-1664463600@www.scilifelab.se
SUMMARY:Context crosstalk of macrophages in cardiovascular disease
DESCRIPTION:Erik A.L. Biessen\, Maastricht University\, the Netherlands \n\n\n\n\n\n\n\n\n\n\nIn this paper\, Biessen et al. introduce a novel approach that integrates 15-plex multispectral immunofluorescent microscopy with mass spectrometry imaging to reveal murine atherosclerotic plaque myeloid heterogeneity. It maps the phenotypes’ tissue localization while allowing their further histological characterization and correlations with their cellular and molecular microenvironmental contexts. \nProf. Erik Biessen graduated in Biophysical Chemistry at Groningen University\, Netherlands (1985). He joined the Division of Biopharmaceutics of Leiden University (Prof. Dr. Th.J.C. Van Berkel) as a post-doctoral fellow and was selected for the prestigious Netherlands Heart Foundation (NHF) funded Molecular Cardiology Program to become Established Investigator in 2001. Dr. Biessen received an innovational research incentive premium of N.W.O in 2001 (VIDI/VICI precursor)\, acquired a second Established Investigatorship of the NHF in 2004\, and was appointed Professor in Therapeutic Gene Modulation at Leiden University in 2005. Since 2007 he is heading the Experimental Vascular Pathology group of CARIM (MUMC). Dr. Biessen has a part-time affiliation at the Institute for Molecular cardiovascular research of RWTH Aachen\, Germany since 2015. Dr. Biessen is/has been a board member of NHS-CVON ( 2010- 2013)\, Dutch Atherosclerosis Society (>2008)\, ZonMW TOP grant committee\, FWO Med6 Expert panel of FWO\, and Ph.D. assessment board of IWT (both Belgium). He is a scientific adviser of VantageView (St Louis\, USA)\, associate editor of Cardiovascular Research and Atherosclerosis\, and participates in several European research programs (e.g. ERA-CVD-AtheroMacHete\, 3 H2020 ITNs (Intricare\, Evolution\, CareSYAN)\, Interreg-EMR Healthy Ageing and EurLipids). Dr. Biessen aims for curiosity-driven cross-disciplinary research with an open eye for the valorization of findings. Through the years his focus has shifted from biophysical chemistry\, via medicinal chemistry and drug targeting to pathomechanistic studies of cardiovascular diseases (>2001)\, with a main emphasis on inflammation.
URL:https://www.scilifelab.se/event/context-crosstalk-of-macrophages-in-cardiovascular-disease/
LOCATION:Air&Fire\, SciLifeLab Stockholm\, Tomtebodavägen 23A\, Solna\, Sweden
CATEGORIES:Event
ORGANIZER;CN="SysMedicine":MAILTO:cheng.zhang@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20220930T160000
DTEND;TZID=Europe/Stockholm:20220930T180000
DTSTAMP:20260404T102931
CREATED:20220829T074202Z
LAST-MODIFIED:20220912T073805Z
UID:10000655-1664553600-1664560800@www.scilifelab.se
SUMMARY:FAIRPoints-FAIR & Open Research 4Beginners
DESCRIPTION:Location: Online via Zoom \n\n\n\n\n\nFuture generations of scientists will benefit from early introduction of Open and FAIR principles. By providing a general understanding of sound\, open\, transparent\, and reproducible research principles and inspiring students we will gain a positive and real change in the academic culture ultimately leading to better research. \n\n\n\n\n\nIntroducing these concepts to the public can also help demystify the research process\, allay public fears about data misuse through inappropriate sharing\, and educate and inform the public about what it really means to work Openly and Reproducibly. \n\n\n\nIt can also be used to persuade the public to support ongoing efforts for Open and FAIR research in order to get the most out of taxpayer funds and garner more interest in participation in citizen science projects. \n\n\n\n \n\n\n\n\n\nWhat we want to do\n\n\n\nWe call for the inclusion of Open and FAIR principles at earlier time points e.g. in the school curriculum to young adults at school and undergraduate students. Together with Edinburgh ReproducibiliTea community we would like to develop training materials for that purpose. \n\n\n\nThe training material should encourage students to reflect on more general values such as transparency and openness in research\,  and motivate them to conduct methodologically sound research avoiding pitfalls associated with a lack of transparency and reproducibility. \n\n\n\nThis is a community led effort towards developing training material which is supported by the offer of a mentorship program provided by Open Life Science (OLS) to encourage individuals who might be interested in learning how to apply open principles in their work and in taking a leading role. \n\n\n\nHow to get involved\n\n\n\nThis is a first of a series of events designed to bring the community together to co-create material needed in different formats\, e.g. training slides\, guidebooks\, video/animations\, infographics etc… \n\n\n\nWe will facilitate the interactions via a series of community check-ins occurring between 4 to 6 weeks intervals\, we also offer biweekly co-working sessions and communications via slack for those who would like to stay in touch while working asynchronously. \n\n\n\nWe welcome all sorts of contributions e.g. input and suggestions\, reviewing\, spreading the word and advertising\, copy editing\, art work! You name it!!  \n\n\n\nJoin us at the kick-off to learn more about our plans and how you can contribute. \n\n\n\nRegister here\n\n\n\nSee event in your TimeZone \n\n\n\n\n\n\n\nAbout FAIRPoints\n\n\n\nFAIRPoints is an event series highlighting pragmatic measures developed by the community towards the implementation of the FAIR (Findable\, Accessible\, Interoperable\, Reusable) data principles\, in collaboration with GoFAIR US\, SDSC\, AGU\, and SciLifeLab Data Centre. \n\n\n\n \n\n\n\nSign up for future events here \n\n\n\nTwitter: @FAIR_Points
URL:https://www.scilifelab.se/event/fairpoints-fair-open-research-4beginners/
LOCATION:Online event via Zoom
CATEGORIES:Event
ORGANIZER;CN="SciLifeLab Data Centre":MAILTO:datacentre@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20221003T120000
DTEND;TZID=Europe/Stockholm:20221003T130000
DTSTAMP:20260404T102931
CREATED:20220919T163016Z
LAST-MODIFIED:20220919T163018Z
UID:10000684-1664798400-1664802000@www.scilifelab.se
SUMMARY:Vibrational Spectroscopy Core Facility - What’s in it for you?
DESCRIPTION:In the frame of the “SciLifeLab Site Umeå / KBC Infrastructure Seminar Series”\, the seminars will be organised every second Tuesday during autumn 2022\, in turn with IceLab Lunch Pitches. The seminars will be held in a hybrid format IRL in Glasburen\, KBC\, and online via Zoom. Take the chance to get information on facilities\, possibilities and services that infrastructure\, both SciLifeLab-associated and local\, can offer! Learn more about the seminar series and the schedule for autumn 2022 here. \n\n\n\nOn October 3rd\, 12:00-13:00\, you are welcome to participate in the seminar \n\n\n\nVibrational Spectroscopy Core Facility – What’s in it for you?\n\n\n\nby Andras Gorzsas\, ViSp facility manager and Senior research engineer at the Department of Chemistry \n\n\n\nSeminar description: The Vibrational Spectroscopy Core Facility provides in situ\, non-destructive\, label-free chemical compositional analysis in the form of FTIR and Raman spectroscopy and imaging. It is an open-access facility with many years of experience in a very broad spectrum of research areas\, from plant sciences and medicine to environmental and material sciences. \n\n\n\nJoin this lunch seminar to see some examples of what this facility can provide for your research\, ask questions and discuss possibilities. \n\n\n\nA tour to the instruments is available after the seminar for those interested. \n\n\n\nRegistration: To register your physical attendance and reserve your free sandwich\, please go to the registration Form \n\n\n\nRead more
URL:https://www.scilifelab.se/event/vibrational-spectroscopy-core-facility-whats-in-it-for-you/
LOCATION:Glasburen Seminar Room\, Chemical Biological Centre (KBC) Building\, Umeå University\, Umeå\, 901 87\, Sweden
CATEGORIES:Event
ORGANIZER;CN="SciLifeLab Ume%C3%A5":MAILTO:umea@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20221003T120000
DTEND;TZID=Europe/Stockholm:20221003T130000
DTSTAMP:20260404T102931
CREATED:20220927T093745Z
LAST-MODIFIED:20220927T102722Z
UID:10000692-1664798400-1664802000@www.scilifelab.se
SUMMARY:Meet the SciLifeLab Göteborg Site
DESCRIPTION:The SciLifeLab national site in Gothenburg\n\n\n\nMaria Smedh\, Site Coordinator\, SciLifeLab Göteborg \n\n\n\nAn overview of the national infrastructure SciLifeLab and the site in Gothenburg. \n\n\n\nSciLifeLab is a national infrastructure within life science with a wide range of advanced technology and expertise. The newly started SciLifeLab site in Gothenburg includes units at both the University of Gothenburg and Chalmers University of Technology and has a strongconnection to Sahlgrenska University Hospital. This seminar series is started with an overview of the site\, followed by presentations by the individual units. \n\n\n\nA light lunch will be offered during the talks for those joining on site. Online participation via Zoom is also available\, please click the zoom-link below to join the event at the appointed time. \n\n\n\nVenue\n\n\n\nAssembly Room Birgit Thilander\, Medicinaregatan 3
URL:https://www.scilifelab.se/event/meet-the-scilifelab-goteborg-site/
LOCATION:Birgit Thilander Lecture Hall\, Medicinaregatan 3\, Göteborg
CATEGORIES:Event
ORGANIZER;CN="SciLifeLab Gothenburg":MAILTO:gothenburg@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20221004T080000
DTEND;TZID=Europe/Stockholm:20221006T170000
DTSTAMP:20260404T102931
CREATED:20220831T141423Z
LAST-MODIFIED:20220912T074844Z
UID:10000662-1664870400-1665075600@www.scilifelab.se
SUMMARY:Swedish NMR meeting 2022
DESCRIPTION:The Swedish Nuclear Magnetic Resonance Spectroscopy (NMR) Meeting 2022 is held in Gothenburg between Oct 4 and 6\, hosted by the Swedish NMR Centre and the VR-funded SwedNMR network. \n\n\n\nRead more and register\n\n\n\nDeadlines:September 16 Registration for Poster Abstracts considered for oral presentationSeptember 28Registration for regular attendance \n\n\n\nRegistration fee and payment informationStudents & postdocs 1000 kr (1250 kr incl VAT)Academic 1500 kr (1875 kr incl VAT)Regular 2000 kr (2500 kr incl VAT)
URL:https://www.scilifelab.se/event/swedish-nmr-meeting-2022/
LOCATION:Conference Centre Wallenberg\, Medicinaregatan 20A\, Gothenburg\, 413 90\, Sweden
CATEGORIES:Event
ORGANIZER;CN="Swedish NMR Centre":MAILTO:info@nmr.gu.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20221006T120000
DTEND;TZID=Europe/Stockholm:20221006T130000
DTSTAMP:20260404T102931
CREATED:20220830T080624Z
LAST-MODIFIED:20220922T120218Z
UID:10000657-1665057600-1665061200@www.scilifelab.se
SUMMARY:Campus Solna Seminar Series: Shaghayegh Bayati and Franziska Ragaller
DESCRIPTION:Welcome to join the Campus Solna Seminar Series – an  initiative to promote the fantastic science ongoing at Campus Solna and hopefully forge more internal communication and collaboration between within Campus Solna. The format consists of two 15 min talks (One speaker from the Alpha-building and one from the Gamma-building respectively)\, with an additional 5 min of questions. Presentation of ongoing (unpublished) projects is strongly encouraged. \n\n\n\nThe seminars are held Thursdays 12:00-13:00. You can bring your lunch to the seminar. \n\n\n\nThis week:\n\n\n\n\n\n\nShaghayegh Bayati\n\n\n\nPeter Nilsson – alpha 2 \n\n\n\nAutoantibody Profiling in Vasculitis and Systemic Sclerosis \n\n\n\n\n\nFranziska Ragaller\n\n\n\nErdinc Sezgin – gamma 3 \n\n\n\nMechanisms of environment sensitivity of smart probes for quantitative assessment of membrane properties \n\n\n\n\n\n\nThis seminar series is organized by the PhD & Postdoc Council. For more information about the Council and other events check our page.
URL:https://www.scilifelab.se/event/campus-solna-seminar-series-oct-6/
LOCATION:Air&Fire\, SciLifeLab Stockholm\, Tomtebodavägen 23A\, Solna\, Sweden
CATEGORIES:Community
ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2022/08/logo_PhD_Postdoc_Council.png
ORGANIZER;CN="SciLifeLab Solna PhD & Postdoc Council":MAILTO:phd-council@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20221007T090000
DTEND;TZID=Europe/Stockholm:20221007T093000
DTSTAMP:20260404T102931
CREATED:20220831T144618Z
LAST-MODIFIED:20220928T142055Z
UID:10000663-1665133200-1665135000@www.scilifelab.se
SUMMARY:[Clinical Talks] Implementing Precision Medicine from a global perspective
DESCRIPTION:Joanne M. Hackett\n\n\n\nHead of Genomic and Precision Medicine at IQVIA \n\n\n\n\n\n\n\nDr Hackett is a clinical academic\, entrepreneur\, investor\, and a strategic\, creative visionair with global experience spanning successful start-ups to Fortune 500 companies. Aside from her curious passion for life and positivity\, Joanne is known for building innovation\, driving personalised medicine and leading through fast paced\, complex changing ecosystems and integrations. Joanne’s goal is to contribute to bringing the world novel\, cost effective and simple health care solutions\, and she is particularly keen on building the case for prevention\, open science and citizen genomics. She has extensive global experience across academic\, business and clinical institutions\, and enjoys sharing her experiences with the Boards she sits on as well as companies she provides strategic advice to. \n\n\n\nJoanne has been publicly recognised for her relentless pursuit of revolutionising healthcare and has been named one of the top six Influential Leaders in Healthcare by CIO Look\, the Accenture Life Science Leader of the year\, Freshfields Top 100 Most Influential Women\, One HealthTech Top 70 Women in the NHS\, Pharmaceutical Market Europe’s 30 women leaders in UK healthcare and BioBeat Top 50 Women in Biotech Award. Joanne believes in human courage and perseverance against the odds\, and demonstrates that positive change\, whether in a company or in one’s personal life\, can be carved out from even the greatest of trials. As a believer of ‘health = wealth’\, Joanne is an internationally known yoga instructor. \n\n\n\nregister to receive zoom link\n\n\n\nModerator: Richard Rosenquist Brandell\, Genomic Medicine Sweden \n\n\n\nIQVIA Inc.\n\n\n\nIQVIA is a leading global provider of advanced analytics\, technology solutions\, and clinical research services to the life sciences industry. IQVIA creates intelligent connections across all aspects of healthcare through its analytics\, transformative technology\, big data resources and extensive domain expertise. IQVIA Connected Intelligence™ delivers powerful insights with speed and agility — enabling customers to accelerate the clinical development and commercialization of innovative medical treatments that improve healthcare outcomes for patients. With approximately 82\,000 employees\, IQVIA conducts operations in more than 100 countries. \n\n\n\nIQVIA is a global leader in protecting individual patient privacy. The company uses a wide variety of privacy-enhancing technologies and safeguards to protect individual privacy while generating and analyzing information on a scale that helps healthcare stakeholders identify disease patterns and correlate with the precise treatment path and therapy needed for better outcomes. IQVIA’s insights and execution capabilities help biotech\, medical device and pharmaceutical companies\, medical researchers\, government agencies\, payers and other healthcare stakeholders tap into a deeper understanding of diseases\, human behavior and scientific advances\, in an effort to advance their path toward cures. To learn more\, visit www.iqvia.com. \n\n\n\n \n\n\n\nClinical Talks\n\n\n\nClinical Talks is back for more! With a brand new and shiny Season 6. After successfully completing 5 seasons with > 70 enthusiastic Clinical Talkers to our record\, we have barely scratched the surface of all the amazing work our clinical\, academic and industry Life Science community has to offer. More about the upcoming events is available here. \n\n\n\nThese events are co-organized by Karolinska Institutet Innovations AB and SciLifeLab\, and brought to you by Colibri Ventures.
URL:https://www.scilifelab.se/event/clinical-talks-implementing-precision-medicine-from-a-global-perspective/
LOCATION:Online event via Zoom
CATEGORIES:Event
ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2022/08/Square-500x500-Clinical-Talks@4x.png
ORGANIZER;CN="Clinical Talks":MAILTO:precisionmedicine@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20221010T090000
DTEND;TZID=Europe/Stockholm:20221014T170000
DTSTAMP:20260404T102931
CREATED:20220621T081729Z
LAST-MODIFIED:20220621T081841Z
UID:10000631-1665392400-1665766800@www.scilifelab.se
SUMMARY:Python programming with applications to bioinformatics
DESCRIPTION:National course open for PhD students\, postdocs\, researchers and other employees in need of fundamental Python skills within all Swedish universities \n\n\n\nResponsible teachers: Nina Norgren\, Dimitris Bampalikis\, Jeanette Tångrot \n\n\n\nContact information: edu.intro-python@nbis.se \n\n\n\n\n\n\n\nVenue\n\n\n\nSciLifeLab Uppsala\, BMC\, Navet (Trippelrummet) \n\n\n\nUmeå University\, KBC building\, room KBG201 \n\n\n\n\n\n\n\nImportant dates\n\n\n\nApplication open: June 21 \n\n\n\nApplication deadline: September 4 \n\n\n\nConfirmation to accepted participants: September 8 \n\n\n\n\n\n\n\nCourse fee\n\n\n\n A course fee* of 2000 SEK will be invoiced to accepted participants. This includes lunches\, coffee and snacks\, and course dinner \n\n\n\n*Please note that NBIS cannot invoice individuals \n\n\n\n\n\n\n\n\n\nCourse website\n\n\n\n\n\nApplication\n\n\n\n\n\n\n\n\n\n\n\n\n\nCourse description\n\n\n\n This course provides a practical introduction to the writing of Python programs for the complete novice. Participants are led through the core aspects of Python illustrated by a series of example programs. Upon completion of the course\, attentive participants will be able to write simple Python programs from scratch and to customize more complex code to fit their needs. \n\n\n\nFormat \n\n\n\nThis course runs in parallel both on-site in Uppsala and in Umeå. Lectures will be streamed online from our Uppsala site to the Umeå site. Several teaching assistants will be present both in the Umeå and Uppsala classroom all week to help with exercises and questions. When registering you will be asked to which site you apply. \n\n\n\nThe course consists of a mix of presentations\, demonstrations\, and practical exercises (either in the lab with assistants or on your own). Prior to the course\, you can read a companion book “Programming Python”\, or “Learning Python”. Such a book will also prove useful for your programming tasks\, after the course is over. It is however not required\, and material will be presented in class. \n\n\n\n\n\n\n\nCourse content\n\n\n\nCore concepts about Python syntax: Data types\, blocks and indentation\, variable scoping\, iteration\, functions\, methods and argumentsDifferent ways to control program flow using loops and conditional testsRegular expressions and pattern matchingWriting functions and best-practice ways of making them usableReading from and writing to filesCode packaging and Python librariesHow to work with biological data using external libraries.\n\n\n\n\n\n\n\nLearning outcomes\n\n\n\nDescribe and apply basic concepts in Python\, such as:LoopsIf/else statementsFunctionsReading/writing to filesBeing able to edit and run Python codeWrite file-processing Python programs that produce output to the terminal and/or external filesCreate stand-alone python programs to process biological dataKnow how to develop your skills in Python after the course (including debugging)\n\n\n\n\n\n\n\nEntry requirements\n\n\n\n The course is suitable for complete beginners and assumes no prior programming experience (beyond the ability to use a text editor). A very basic knowledge of UNIX would be an advantage\, such as navigating through folders and issuing commands at a shell prompt. We will not teach UNIX in detail: Other courses are available at SciLifeLab for it. Make sure your laptop has python installed for the practical exercises. \n\n\n\n\n\n\n\nSelection criteria\n\n\n\nDue to limited space the course can accommodate a maximum of 25 participants in Uppsala and 15 in Umeå. If we receive more applications\, participants will be selected based on several criteria. Selection criteria include correct entry requirements\, motivation to attend the course as well as gender and geographical balance. Please note that NBIS training events do not provide any formal university credits. The training content is estimated to correspond to 1.5 hp credits\, however the estimated credits are just recommendations. If formal credits are crucial\, the student needs to confer with the home department before submitting a course application in order to establish whether the course is valid for formal credits or not
URL:https://www.scilifelab.se/event/python-programming-with-applications-to-bioinformatics/
CATEGORIES:Course
ORGANIZER;CN="NBIS - National Bioinformatics Infrastructure Sweden":MAILTO:education@nbis.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20221011T080000
DTEND;TZID=Europe/Stockholm:20221013T170000
DTSTAMP:20260404T102931
CREATED:20220912T161617Z
LAST-MODIFIED:20220912T161619Z
UID:10000680-1665475200-1665680400@www.scilifelab.se
SUMMARY:Cryo-EM sample preparation and data collection course
DESCRIPTION:The purpose of the course is to prepare and train Cryo-EM facility users in sample preparation methods\, introduce users to the image data acquisition workflow\, expand knowledge about cryo-EM methods among researchers and show that everyone can learn how to use cryo-EM for structure and cell biology. \n\n\n\nThe course is open for facility users or potential facility users\, such as PhD students\, postdocs\, and researchers within the life sciences who are curious and will profit from cryo-EM skills. Swedish and international course participants are welcome. To attend\, the course participants must have experience in basic electron microscopy and be familiar with structure or cell biology. \n\n\n\nThis course is supported by SciLifeLab\, CryoNET and Umeå University and organized by the SciLifeLab Cryo-EM facility\, both UmU and SU nodes together. \n\n\n\nApplication deadlineApplication should be submitted before September 16\, 2022 \n\n\n\nRead more\n\n\n\nCourse organizersCamilla Holmlund and Michael Hall \n\n\n\nLocationUCEM and Chemical Biological Centre (KBC) BuildingUmeå UniversityLinnaeus väg 6 \n\n\n\nTeachers and course instructors \n\n\n\nLinda SandbladMichael HallLars-Anders CarlsonCamilla HolmlundAdditional teachers t.b.a\n\n\n\nSocial programA social program depending on the current corona restriction will be communicated to the participants after acceptance. \n\n\n\nCourse feeA course fee of 800 SEK\, including coffee and lunches\, will be invoiced to accepted participants after acceptance. \n\n\n\nCourse contentThis course will cover practical aspects of cryo-EM sample preparation and data acquisition.Topics covered: \n\n\n\nBasic theory of vitreous water\, how to handle a cryo sample and consequencesPlunge freezing methods\, tools and cryo-transferSample and instrument requirements for single particle and tomography methodsImage data acquisition\, concept of low dose and the cryo-specific workflowIntroduction to automatic data acqui­sition software\, EPU\, TomographyIntroduction to cryo-EM image processing methods\n\n\n\nThe course consists of lectures\, cryo lab work\, demonstrations and practical exercises for all participants\, hands-on experiences of microscopy operation and discussions. A detailed schedule will be provided to accepted participant. \n\n\n\nCourse literatureHandouts and material online. \n\n\n\nEntry requirementsPriority will be given to researchers involved in project where the use of cryo-EM is needed\, which are to be briefly described upon application. \n\n\n\nThe course will be held at an advanced level\, assuming that participants have a master’s degree or equivalent in a technical life science discipline. It aims to be relevant for a broad research community\, also to participants not working in research environments using cryo-EM today. \n\n\n\nA maximum of 15 participants will be admitted. Selection criteria include correct entry requirements\, motivation to attend the course as well as gender balance. \n\n\n\nExamination Participation in all parts of the course\, lectures\, lab\, microscopy demonstrations and evaluation are mandatory. SciLifeLab and Umeå University will provide successful participants with a course certificate and a recommendation for 1 ECTS
URL:https://www.scilifelab.se/event/cryo-em-sample-preparation-and-data-collection-course/
CATEGORIES:Course
ORGANIZER;CN="SciLifeLab Ume%C3%A5":MAILTO:umea@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20221011T090000
DTEND;TZID=Europe/Stockholm:20221011T120000
DTSTAMP:20260404T102931
CREATED:20220920T161925Z
LAST-MODIFIED:20220927T123606Z
UID:10000686-1665478800-1665489600@www.scilifelab.se
SUMMARY:BioImage Analysis support – Call4Help
DESCRIPTION:Every month (mainly on Tuesdays\, but there might be exceptions) the BioImage Informatics Facility together with microscopy expert Sylvie Le Guyader (LCI\, Karolinska Institutet) organizes a Call4Help session. The aim is to offer combined expertise towards microscopy and bioimage analysis. All researchers from Swedish institutes can participate. \nThe ideal timepoint to join the Call4Help session is when a researcher has performed pilot experiments and has tried out first analysis approaches – but before having recorded hundreds of images. Combining BIIF’s expertise in BioImage Analysis with microscopy expertise we can discuss ways to record the images that allow analysis afterwards. We will discuss different analysis approaches using mainly open-source software (Fiji\, CellProfiler\, QuPath\, Ilastik\, KNIME)\, but also commercial systems\, if needed (Imaris). \nThe Call4Help session format has been introduced to the BioImage Analysis community by NEUBIAS and ScopeM. \n  \nHow to participate? \nStep1: \nPrepare a short presentation (5-7 min)  – use the following template for your presentation: \nhttp://bit.ly/BIIF_C4H_slideTemplate \nSlide template by NEUBIAS/ScopeM \nStep2: \n\na) Upload your presentation \n\n  \nUpload your presentation to a drive of your choice. You can also use our Call4Help google drive. Note that files shared on our Call4Help drive will be available to everyone until the session is over. \nhttp://bit.ly/BIIF_C4H_Drive \n\nb) Upload example images for testing. \n\nUpload example images for testing either to the drive of your choice or our Call4Help google drive above. \nhttp://bit.ly/BIIF_C4H_Drive \n\nc) Register by filling out the registration form: \n\nhttp://bit.ly/BIIF_C4H_Registration \nStep 3: \nJoin the zoom-session. \nIf your problem is selected for presentation\, you will get a time-slot of 30 – 60 minutes within the session. \n  \nWhat are the Deadlines \nSubmission of a problem and upload of example data: Friday the week before the session. \nNotification about participation: The day before the session. \nNext Call4Help session: Tuesday\, October 11\, 2022\, 9.00-12.00 \nDeadline for application: Friday\, October 7\, 2022
URL:https://www.scilifelab.se/event/bioimage-analysis-support-call4help-7/
LOCATION:Online event via Zoom
CATEGORIES:Event
ORGANIZER;CN="Bioimage Informatics Unit":MAILTO:biif@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20221011T090000
DTEND;TZID=Europe/Stockholm:20221013T170000
DTSTAMP:20260404T102931
CREATED:20220621T074909Z
LAST-MODIFIED:20220831T075512Z
UID:10000630-1665478800-1665680400@www.scilifelab.se
SUMMARY:Introduction to Data Management Practices
DESCRIPTION:National course open for PhD students\, postdocs\, researchers and other employees within all Swedish universities. This course will introduce important aspects of Research Data Management through a series of lectures and hands-on computer exercises. The course is intended for researchers that want to take the first steps towards a more systematic and reproducible approach to analysing and managing research data. \n\n\n\nNote: We follow the recommendations and guidelines from Swedish authorities and Folkhälsomyndigheten. The course is designed to be an interactive face-to-face event. However\, we follow the situation carefully and will deliver the course online if needed. \n\n\n\nContact: edu.intro-dm@nbis.se \n\n\n\n\n\n\n\nImportant dates\n\n\n\nApplication opens:  open now \n\n\n\nApplication closes:  2022-09-09 \n\n\n\nConfirmation to accepted students:  2022-09-13 \n\n\n\n\n\n\n\n\n\nCourse Website\n\n\n\n\n\nApplication\n\n\n\n\n\n\n\n\n\n\n\n\n\nCourse fee\n\n\n\n1500 SEK paid by invoice to NBIS. This includes lunches\, coffee and snacks. Please note that NBIS cannot invoice individuals. \n\n\n\nDue to limited space the course can accommodate a maximum of 25 participants. If we receive more applications\, participants will be selected based on several criteria. Selection criteria include correct entry requirements\, motivation to attend the course as well as gender and geographical balance. \n\n\n\n\n\n\n\nCourse content\n\n\n\nTopics covered will include \n\n\n\n• Open Science and FAIR in practice \n\n\n\n• Organising data\, files and folders in research projects \n\n\n\n• Versioning data\, documents and scripts with Git \n\n\n\n• Describing data with metadata \n\n\n\n• Cleaning tabular data and metadata with OpenRefine \n\n\n\n• Submitting data to public data repositories \n\n\n\n• Writing basic recipes for data analysis and visualisation with R \n\n\n\n\n\n\n\nLearning objectives \n\n\n\n• To get acquainted with\, and reflect upon\, the principles of Open Science and FAIR \n\n\n\n• To understand the importance of metadata\, and how it affects “FAIRness” \n\n\n\n• To learn how to organise files to make project work more efficient \n\n\n\n• To learn to clean up messy tabular data and metadata \n\n\n\n• To learn how to find\, and submit to\, relevant public repositories for data publication \n\n\n\n• To learn to apply simple version control practices on files \n\n\n\n• To learn to start using R to analyse data \n\n\n\n\n\n\n\nEntry requirements\n\n\n\nNo previous programming experience is required but you are required to bring your own laptop with the required software pre-installed. Installation instructions will be provided before the course starts.
URL:https://www.scilifelab.se/event/introduction-to-data-management-practices-3/
LOCATION:Air&Fire\, SciLifeLab Stockholm\, Tomtebodavägen 23A\, Solna\, Sweden
CATEGORIES:Course
ORGANIZER;CN="NBIS - National Bioinformatics Infrastructure Sweden":MAILTO:education@nbis.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20221011T120000
DTEND;TZID=Europe/Stockholm:20221011T130000
DTSTAMP:20260404T102931
CREATED:20220927T104040Z
LAST-MODIFIED:20220927T104229Z
UID:10000693-1665489600-1665493200@www.scilifelab.se
SUMMARY:Clinical Genomics Gothenburg - Infrastructure and Research services
DESCRIPTION:Clinical Genomics Gothenburg – Infrastructure and Research services\n\n\n\nMeena Kanduri\, Clinical Genomics\, SciLifeLab Göteborg \n\n\n\nJoin us to learn more about the NGS-based services and the bioinformatic support that we offer at Clinical Genomics Gothenburg (CGG) unit with a focus towards translational and clinical research. \n\n\n\nSciLifeLab is a national infrastructure within life science with a wide range of advanced technology and expertise. The newly started SciLifeLab site in Gothenburg includes units at both the University of Gothenburg and Chalmers University of Technology and has a strongconnection to Sahlgrenska University Hospital. This seminar series is started with an overview of the site\, followed by presentations by the individual units. \n\n\n\nA light lunch will be offered during the talks for those joining on site. Online participation via Zoom is also available\, please click the zoom-link below to join the event at the appointed time. \n\n\n\nVenue\n\n\n\nAssembly Room Birgit Thilander\, Medicinaregatan 3
URL:https://www.scilifelab.se/event/clinical-genomics-gothenburg-infrastructure-and-research-services/
LOCATION:Birgit Thilander Lecture Hall\, Medicinaregatan 3\, Göteborg
CATEGORIES:Event
ORGANIZER;CN="SciLifeLab Gothenburg":MAILTO:gothenburg@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20221013T120000
DTEND;TZID=Europe/Stockholm:20221013T130000
DTSTAMP:20260404T102931
CREATED:20220830T080828Z
LAST-MODIFIED:20220927T110646Z
UID:10000658-1665662400-1665666000@www.scilifelab.se
SUMMARY:Campus Solna Seminar Series: Aditi Shenoy and Jean Froment
DESCRIPTION:Welcome to join the Campus Solna Seminar Series – an  initiative to promote the fantastic science ongoing at Campus Solna and hopefully forge more internal communication and collaboration between within Campus Solna. The format consists of two 15 min talks (One speaker from the Alpha-building and one from the Gamma-building respectively)\, with an additional 5 min of questions. Presentation of ongoing (unpublished) projects is strongly encouraged. \n\n\n\nThe seminars are held Thursdays 12:00-13:00. You can bring your lunch to the seminar. \n\n\n\nThis week:\n\n\n\n\n\n\nAditi Shenoy\n\n\n\nArne Elofsson – alpha 6 \n\n\n\nEvaluation of AlphaFold-Multimer predictions – edge cases and exploring its utility for binding-site prediction \n\n\n\n\n\nJean Froment\n\n\n\nJonathan Martin – gamma 5 \n\n\n\nWhy is the air toxic? Virtual effects-directed analysis (vEDA) of fine particulate matter (PM2.5) \n\n\n\n\n\n\nThis seminar series is organized by the PhD & Postdoc Council. For more information about the Council and other events check our page.
URL:https://www.scilifelab.se/event/campus-solna-seminar-series-oct-13/
LOCATION:Air&Fire\, SciLifeLab Stockholm\, Tomtebodavägen 23A\, Solna\, Sweden
CATEGORIES:Community
ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2022/08/logo_PhD_Postdoc_Council.png
ORGANIZER;CN="SciLifeLab Solna PhD & Postdoc Council":MAILTO:phd-council@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20221013T150000
DTEND;TZID=Europe/Stockholm:20221013T160000
DTSTAMP:20260404T102931
CREATED:20221005T141602Z
LAST-MODIFIED:20221005T141605Z
UID:10000708-1665673200-1665676800@www.scilifelab.se
SUMMARY:Structural proteogenomics analyses of circulating antibody repertoires
DESCRIPTION:We showcase a novel structural proteogenomics workflow to decipher the properties of circulating antibody repertories relating to immunity against bacteria and viruses. \n\n\n\nProf. Johan Malmström\, Lund University \n\n\n\nOctober 13th\, 15:00-16:00 SciLifeLab Gamma-2 lunchroom
URL:https://www.scilifelab.se/event/structural-proteogenomics-analyses-of-circulating-antibody-repertoires/
LOCATION:Gamma 2 Lunchroom\, SciLifeLab\, Tomtebodavägen 23\, Solna\, Sweden
CATEGORIES:Event
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20221013T151500
DTEND;TZID=Europe/Stockholm:20221013T163000
DTSTAMP:20260404T102931
CREATED:20221005T112555Z
LAST-MODIFIED:20221005T113202Z
UID:10000707-1665674100-1665678600@www.scilifelab.se
SUMMARY:[The Svedberg seminar] Prof. Jay Hinton
DESCRIPTION:University of Liverpool\, UK \n\n\n\nTime: 15:15Venue: C8:305\, BMC\, Uppsala \n\n\n\nHost: Siv Andersson\, Uppsala University \n\n\n\nProf. Jay Hinton is Professor of Microbial Pathogenesis at the University of Liverpool. Prof. Prof. Hinton has developed RNA-seq-based approaches for studying gene expression of in vitro-grown and intra-macrophage bacteria. He is currently using functional genomics methods to understand how new Salmonella pathovariants are causing endemic bloodstream infections across sub-Saharan Africa. This disease has killed around 500\,000 people over the last decade. \n\n\n\nTitle of the talk: How has Salmonella become so dangerous in Africa?\n\n\n\nWith 3.4 million infections each year\, invasive non-Typhoidal Salmonella (iNTS) is a major cause of illness worldwide. In Sub-Saharan Africa\, bloodstream infections involving iNTS Salmonella enterica serovar Typhimurium are causing ~49\,000 deaths annually. Co-infection with HIV or malaria in adults\, and a young age (<5 years) are known risk factors. The main causative agent of iNTS is a pathovariant of Salmonella Typhimurium called ST313\, which is multi-drug resistant and closely-related to the ST19 type of Salmonella responsible for gastroenteritis globally. \n\n\n\nUsing a combination of comparative genomics and comparative transcriptomics\,we discovered phenotypic differences that distinguish African from global Salmonella pathovariants (Canals et al.\, 2019; Honeycutt et al.\, 2020). \n\n\n\nOur analysis led us to identify a single core genome SNP responsible for the up-regulation of a single promoter in strain D23580 that controlled the expression of a Salmonella virulence factor (Hammarlöf et al.\, 2018)\, and offers part of the explanation of the pan-African epidemic of bloodstream infection.All of the Salmonella transcriptomic data we have generated are now available online in a user-friendly website that allows intra-strain and inter-strain comparisons of gene expression between African and global pathovariants ofS. Typhimurium: https://tinyurl.com/SalComD23580 \n\n\n\nMost recently\, we used the combined power of genomics and epidemiology and thousands of historical and contemporary Salmonella isolates to understand the precise evolutionary trajectory of the S. Typhimurium ST313 pathogen in Africa. We identified a series of novel genome degradation events that impacted upon the function of Salmonella genes required for colonisation of the mammalian gut\, providing evidence of niche adaptation and the continuing evolution of ST313 (Pulford et al.\, 2021). \n\n\n\nI will summarise the evolutionary pathway of invasive S. Typhimurium across Africa\, and explain the value of an integrated functional genomic analysis for understanding how bacterial pathogens cause disease. \n\n\n\nReferencesCanals et al. (2019) Adding function to genome of African Salmonella Typhimurium ST313. PLoS Biology 17(1): e3000059. DOI: 10.1371/journal.pbio.3000059 \n\n\n\nHammarlöf et al. (2018) Role of a single noncoding nucleotide in the evolution of an epidemic African clade of Salmonella. PNAS 115: E2614 – E2623. \n\n\n\nDOI: 10.1073/pnas.1714718115 \n\n\n\nHoneycutt et al. Genetic variation in the MacAB-TolC efflux pump influences pathogenesis of invasive Salmonella isolates from Africa. PLoS Pathog. 2020 16:e1008763. DOI: 10.1371/journal.ppat.1008763 \n\n\n\nPulford et al. (2021) Stepwise evolution of Salmonella Typhimurium ST313 causing bloodstream infection in Africa. Nature Microbiology 6: 327–338. \n\n\n\nDOI:10.1038/s41564-020-00836-1
URL:https://www.scilifelab.se/event/the-svedberg-seminar-prof-jay-hinton/
CATEGORIES:Event
ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2022/02/Picture1-The-Svedberg.png
ORGANIZER;CN="The Svedberg Seminar Series":MAILTO:thesvedberg@scilifelab.uu.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20221014T153000
DTEND;TZID=Europe/Stockholm:20221014T170000
DTSTAMP:20260404T102931
CREATED:20221010T171937Z
LAST-MODIFIED:20221010T172151Z
UID:10000711-1665761400-1665766800@www.scilifelab.se
SUMMARY:The Dark Side of Science: Misconduct in Biomedical Research
DESCRIPTION:Researchers in all stages of their career are welcome to attend and could find the talk useful. Kindly feel free to extend the invitation to your home universities.  \n\n\n\nFlyer-BAM-Elisabeth-BikDownload\n\n\n\nScience builds upon science. Even after peer-review and publication\, science papers could still contain images or other data of concern. If not addressed post-publication\, papers containing incorrect or even falsified data could lead to wasted time and money spent by other researchers trying to reproduce those results. Several high-profile science misconduct cases have been described\, but many more cases remain undetected. Elisabeth Bik is an image forensics detective who left her paid job in industry to search for and report biomedical articles that contain errors or data of concern. She has done a systematic scan of 20\,000 papers in 40 journals and found that about 4% of these contained inappropriately duplicated images. In her talk she will present her work and show several types of inappropriately duplicated images and other examples of research misconduct. In addition\, she will show how to report scientific papers of concern\, and how journals and institutions handle such allegations. \n\n\n\nElisabeth Bik\, PhD is a Dutch-American microbiologist who has worked for 15 years at Stanford University and 2 years in industry. Since 2019\, she is a science integrity volunteer and consultant who scans the biomedical literature for images or other data of concern and has reported over 6\,000 scientific papers.  Her work has resulted in over 900 retracted and almost 1\,000 corrected papers.  \n\n\n\nWho the event is aimed at i.e.\, who will attend:  Researchers in all stages of their career are welcome to attend and could find the talk useful. Kindly feel free to extend the invitation to your home universities.  \n\n\n\nSpeakers: Dr. Elisabeth Bik
URL:https://www.scilifelab.se/event/the-dark-side-of-science-misconduct-in-biomedical-research/
LOCATION:Online event via Zoom
CATEGORIES:Event
ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2022/08/logo_PhD_Postdoc_Council.png
ORGANIZER;CN="SciLifeLab Solna PhD & Postdoc Council":MAILTO:phd-council@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20221017T100000
DTEND;TZID=Europe/Stockholm:20221018T140000
DTSTAMP:20260404T102931
CREATED:20220622T085908Z
LAST-MODIFIED:20221128T095930Z
UID:10000634-1666000800-1666101600@www.scilifelab.se
SUMMARY:Facility Forum
DESCRIPTION:Facility Forum is a two-day event exclusively for the SciLifeLab infrastructure community\, including platform and unit leadership\, staff\, and administrative personnel\, as well as central management and support teams.  \n\n\n\nThe event aims to bring everyone updated on what is cooking at SciLifeLab\, promote cross-platform and cross-unit interactions\, and enable discussions on urgent topics related to infrastructure operations. We offer inspiring talks\, network activities\, discussions in parallel sessions\, and dinner with entertainment in the evening on day one. The second day is devoted to platform-wise activities and ends with a joint lunch. We have a maximum number of participants (400p). \n\n\n\nYour participation includes the following: \n\n\n\n\nBus from/to Cityterminalen\, Tomtebodavägen Solna or BMC Uppsala\n\n\n\nConference program\n\n\n\nLunches and coffee breaks\n\n\n\nTeamwork activity\n\n\n\nConference dinner\n\n\n\nOvernight stay in a single/double room (only for participants of Day 1+2)\n\n\n\n\n\n\n\n\nBus transport to Djurönäset\, Oct 17\n\n\n\nDeparture from BMC Uppsala at exactly 07:15 \n\n\n\nDeparture from Tomtebodavägen 23\, Solna at exactly 08:00 \n\n\n\nDeparture from Cityterminalen\, Stockholm at exactly 08:30(Gate number is shown on the digital screens inside the terminal building\, 30 minutes before departure) \n\n\n\nBus transport from Djurönäset\, Oct 18\n\n\n\n14:00 Busses to Cityterminalen\, BMC Uppsala\, and Tomtebodavägen departs from Djurönäset \n\n\n\n\n\n\n\nBus transport to Fågelbrohus\, evening Oct 17 and morning Oct 18\n\n\n\nThe event is fully booked\, and accommodation (single room) at Fågelbrohus (about 10 minutes by bus) has been arranged for the latest registered participants. The Fågelbrohus residents are welcome to use the SPA at Djurönäset before dinner.  \n\n\n\n22:00 Bus departs to Fågelbrohus \n\n\n\n23:30 Bus departs to Fågelbrohus \n\n\n\n08:30 Bus departs to Djurönäset from Fågelbrohus \n\n\n\n\n\n\n\nProgram\n\n\n\n\nDownload Program\n\n\n\n\n\n\n\n\nProgram\nOctober 17\n\n\n\n09:00Coffee\, sandwich\, and registration10:00Welcome. SciLifeLab talk show with guests\, Stora KongressenShort break 11:00-11:30 and 12:00-12:10 12:45Conference lunch13:45Drop-in Poster session and coffee\, Stora Kongressen14:30Teamwork activity\, instructions from the stage\, Stora KongressenCoffeeCheck-in15:30Parallel sessions (see Workshops A-G below) 17:00Free time\, SPA available18:15Aperitif and music\, Lounge\, main building19:00Conference dinner and entertainment\n\n\n\nOctober 18\n\n\n\n09:00Platform-wise program09:00 Platform-wise programClinical Genomics\, House 7\, Room Lilla KongressenOperations office/SISU\, Room 1K+1ASpatial and Single Cell Biology\, Room 2AGenomics\, Room 3ADDD\, Room\, 4ABioinformatics\, Room 5AClinical Proteomics and Immunomonitoring\, Room 6ACBGE\, Room 1ECellular and Molecular Imaging\, Room 2EIntegrated Structural Biology\, Room 3EMetabolomics\, Room 4EData center\, Room 5E09:30Coffee is served in the lounge\, outside the meeting rooms from 09:30-11:00. Special requirements in House 6.12:45Conference lunch14:00Bus transfer\n\n\n\n \n\n\n\n\n\n\n\n\nWorkshops\n\n\n\nSciLifeLab Training Hub\nMeet the team for the SciLifeLab Training Hub to discuss how training\, courses\, lifelong learning\, and education of the infrastructure users should be organized in a nationally coordinated model to optimally serve both the platforms and the Swedish life science research community.  \n\n\n\nLocation: ROOM 6A \n\n\n\nWorkshop leader\n\n\n\nJessica Lindvall \n\n\n\n\nHow do you reach out? – Improve your communication skills\nReflections and advice on reaching out to target groups outside science with a focus on presentation techniques. \n\n\n\nContents include \n\n\n\n\nFive core principles of effective communication\n\n\n\nPopularizing science – some hands-on advice\n\n\n\nThe Five Ps: Planning\, Preparing and Performing Persuasive Presentations\n\n\n\nPreparing an elevator pitch – a walkthrough\n\n\n\nPractical advice for connecting with the audience\n\n\n\n\nLocation: ROOM 2A \n\n\n\nWorkshop leader\n\n\n\nOlle Bergman \n\n\n\n\nHow to serve academic vs non-academic infrastructure users and the work towards harmonized SciLifeLab models\nMeet the SciLifeLab External Relations Office and SciLifeLab/KTH lawyer to discuss models to interact with different user categories\, user fee policies\, priorities\, contracts\, legal aspects\, and intellectual property rights.  \n\n\n\nLocation: ROOM 4A \n\n\n\nWorkshop Leader\n\n\n\nJosefin Lundgren Gawell \n\n\n\n\nIT and data management services for SciLifeLab infrastructure\nMeet representatives from SciLifeLab Data Centre to find out about services available for your platform/unit and to discuss future needs. Learn about the Data Centre plans and how to get involved in testing of upcoming systems and services.  \n\n\n\nLocation: ROOM 3A \n\n\n\nWorkshop leader\n\n\n\nHanna Kultima \n\n\n\n\nPrecision medicine at SciLifeLab\nHow can the infrastructure contribute to implementation of precision medicine into routine clinical care in Sweden? An interactive workshop and discussion with representatives from the SciLifeLab Precision Medicine team.  \n\n\n\nLocation: ROOM LILLA KONGRESSEN\, 7A \n\n\n\nWorkshop leader\n\n\n\nÅsa Johansson \n\n\n\n\nQuality aspects of infrastructure operations\, data handling and scientific output\nIn the light of the recommendations from our International Advisory Board\, this workshop will focus on discussions on how to increase the quality of the research that is facilitated by the infrastructure. This involves among other things aspects of the service repertoire\, modes of operation\, cross-platform interactions\, and data handling.  \n\n\n\nLocation: ROOM 1A \n\n\n\nWorkshop leader\n\n\n\nAnnika Jenmalm Jensen \n\n\n\n\nPlanetary Biology – understanding ecosystems from molecular to planetary scale\nMeet the scientific leads of the recently launched Planetary Biology capability at SciLifeLab and find out more about the mission and vision. Brainstorm with us about what technologies and methods in the SciLifeLab infrastructure toolbox could be of value to the target research community in visionary and forward-looking discussions.  \n\n\n\nLocation: ROOM 5A \n\n\n\nWorkshop Leaders\n\n\n\nStefan Bertilsson & Olga Vinnare Pettersson \n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\nImportant information\n\n\n\nRegistration: Registration has closed\, and we have a waiting list. We have 400 p. registered for Facility Forum. \n\n\n\nCancellations: In the unfortunate case that you need to cancel your participation\, send an email to infra@scilifelab.se ASAP so we can have someone from the waiting list take your place. \n\n\n\nParallel sessions: All the participants have been granted their first choice of workshop.  \n\n\n\nOvernight stay: Only participants of Day 2 are allowed the overnight stay. We have exceeded the number of rooms available at Djurönäset\, så the last registered persons will stay at Hotel Fågelbrohus. A bus transfer from/to Djurönäset (about 10 minutes) will be provided in the evening and the morning. We have used the first-come-first-served principle\, and a large number of people are accommodated with a roommate. All double rooms have separate beds. If you can stay in a double room\, let us know your room mate. \n\n\n\nConference dinner: If necessary\, priority will be given to people participating for two days. \n\n\n\nGetting there by public transport: Visit www.sl.se and make a query for your journey – e.g. from T-centralen to Djurönäset. Bus 433 and bus 434 departs regularly from Slussen to Djurönäset. \n\n\n\nFor questions about Facility Forum\, please contact infra@scilifelab.se \n\n\n\n \n\n\n\nOrganizing committee\n\n\n\nChair: Annika Jenmalm Jensen\, SciLifeLab Infrastructure Director \n\n\n\nOperations office: Erika Bergqvist Erkstam\, project leader\, Maria Bäckström\, David Gotthold\, Lars Johansson\, Alice Sollazzo\, Samuel Avraham\, Charlotte Stadler\, Björn Nystedt\, and with fantastic support from the Platform Coordination Officers.
URL:https://www.scilifelab.se/event/facility-forum/
LOCATION:Djurönäset\, Seregårdsvägen 1\, Djurhamn
CATEGORIES:Community
ATTACH;FMTTYPE=image/jpeg:https://www.scilifelab.se/wp-content/uploads/2022/06/ff_temabild-scaled.jpg
ORGANIZER;CN="Operations office":MAILTO:events@SciLifeLab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20221017T151500
DTEND;TZID=Europe/Stockholm:20221017T161500
DTSTAMP:20260404T102931
CREATED:20221009T184510Z
LAST-MODIFIED:20221009T185208Z
UID:10000710-1666019700-1666023300@www.scilifelab.se
SUMMARY:[The Svedberg] - Manfred Schartl
DESCRIPTION:Developmental Biochemistry\, University of Würzburg\, Germany \n\n\n\nTime: 15:15Venue: C8:305\, BMC\, Uppsala \n\n\n\nHost: Leif Andersson\, Uppsala University \n\n\n\nTitle of the talk: Evolution of sex determination and sex chromosomes in fish \n\n\n\nBio: Prof. Manfred Schartl studied Biology and Chemistry at the University of Giessen\, Germany\, and graduated in Genetics. After postdoctoral research in Giessen and at the NIH in Bethesda he was team leader of a research group from 1985 to 1991 at the Gene Center of the Max Planck Institute for Biochemistry in Martinsried\, Germany. Until 2019 he was full professor and chairman of Physiological Chemistry at the Biocenter of the University of Würzburg. Currently\, he heads a research group as senior professor at the Biocenter and works as scholar in residence at the Xiphophorus Genetic Stock Center at Texas State University in San Marcos. He is member of the German Academy of Sciences\, Leopoldina\, and the European Academy of Sciences\, Academia Europea. He holds an honorary doctorate from the University of Bergen\, Norway.He uses the small aquarium fish biomedical models Xiphophorus and Medaka to understand molecular processes of organ development and their malfunction in disease with a focus on pigment cells and melanoma and another one on sex determination and gonad development. Key to his research is taking an evolutionary perspective to answer these questions on the basis of comparative genomics and molecular biology experimental studies. \n\n\n\nAbstract: Sex determination (SD) is unique biological process in showing an astonishing plasticity of mechanisms. Fish present the greatest variability of SD amongst vertebrates. In the case of genetic SD this is linked to a similarly high variability of sex chromosome differentiation. While in a handful of species with genetic SD the master SD genes have been identified\, their molecular function in directing the development of the bipotential gonad primordium towards testis or ovary is unclear in many cases or incompletely known in the others. To obtain a deeper understanding of this diversity we need a better knowledge of the molecular basis of SD mechanisms and the structure and genetic organization of sex chromosomes across a broad diversity of fish. To identify sex chromosomes and primary SD genes\, we use high throughput RAD-tag marker mapping\, transcriptomics\, Pool-Seq and whole genome sequencing to identify sex-specific chromosomal regions and candidate SD genes in sharks\, sturgeons and teleosts. This led to the identification of sex-specific markers\, allowing to delineate the extent of recombination suppression\, which turned out to be highly variable between species. We identified several species with clear cut XX/XY or ZZ/ZW monofactorial systems but also species with more complex sex-determination systems including species with a mix of genetic SD and environmental SD and species with potential polygenic systems. In species with available genomic resources\, sex-specific markers could be used to assign scaffolds to regions that are supposed to contain the primary SD gene. We identified candidate genes in several species and find that most of them belong to already known factors of the primary SD regulatory network including candidate genes that have not been found so far as being SD genes. We also find that many species harbor very poorly differentiated sex-chromosomes. The SD variety does not follow a phylogenetic pattern\, and turnovers of the genetic SD system from male to female heterogamety and vice versa are frequent in some groups\, making the evolutionary instability of SD a spectacular trait whose biological meaning is not yet understood.
URL:https://www.scilifelab.se/event/the-svedberg-manfred-schartl/
CATEGORIES:Event
ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2022/02/Picture1-The-Svedberg.png
ORGANIZER;CN="The Svedberg Seminar Series":MAILTO:thesvedberg@scilifelab.uu.se
END:VEVENT
END:VCALENDAR