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BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20231206T080000
DTEND;TZID=Europe/Stockholm:20231208T170000
DTSTAMP:20260404T104101
CREATED:20231002T115541Z
LAST-MODIFIED:20231002T115646Z
UID:10000980-1701849600-1702054800@www.scilifelab.se
SUMMARY:DDLS Biomarker Discovery: from theory to real world examples
DESCRIPTION:National workshop open for PhD students\, postdocs\, researchers and other employees in all Swedish universities\, in need of understanding biomarker research and methods. \n\n\n\nWorkshop location:  SciLifeLab\, Tomtebodavägen 23A\, Solna \n\n\n\nVenue:  Air&Fire (G2690) and Milky Way (A2631) \n\n\n\n\n\n\n\nImportant dates and information\n\n\n\nApplication opens: 2023-10-01 \n\n\n\nApplication closes: 2023-10-30 \n\n\n\nConfirmation to accepted students: 2023-11-15 \n\n\n\n \n\n\n\nCourse Leaders and teachers: Animesh Acharjee\, Clemens Wittenbecher\, Markus Mayrhofer\, Mun-Gwan Hong\, Paul Pyl\, Prasoon Agarwal \n\n\n\nplease contact edu.biomarkers@nbis.se for course-specific questions \n\n\n\n\n\n\n\nApplication\n\n\n\n\n\n\n\nWorkshop fee\n\n\n\nA course fee* of 2000 SEK will be invoiced to accepted participants. The fee includes lunch and coffee. \n\n\n\n*Please note that NBIS cannot invoice individuals \n\n\n\n\n\n\n\nWorkshop content\n\n\n\nThe main purpose of this workshop is to provide a good overview of biomarkers and biomarker studies. This workshop will explore recent research\, showcasing diverse biomarker applications within clinical trials. Methods employed to identify biomarkers through various omics datasets will be reviewed. Participants will engage in discussion on biomarker studies and data analysis exercises that encompass approaches like machine learning methods and other integrative omics strategies used in biomarker discovery. \n\n\n\nTopics covered will include: \n\n\n\n\nBiomarker study design for “context of use”\n\n\n\nTypes of biomarkers\, diagnostic\, prognostic\, and wellness\n\n\n\nBiomarkers are in use for various diseases such as cancer\, cardiovascular diseases\n\n\n\nBiomarker discovery from various omics data including proteome\, microbiome\n\n\n\nBiomarker and multi-omics data integration\n\n\n\nMachine learning methods\, lasso logistic regression and random forest\, to identify biomarkers\n\n\n\nPerformance indicators\, e.g. sensitivity and specificity\n\n\n\nInternal/external validation\n\n\n\n\n\n\n\n\nEntry requirements\n\n\n\nThe following is a list of skills required to be able to follow the workshop and complete the exercises: \n\n\n\n\nAbility to bring your own laptop with R installed for the practical exercises\n\n\n\nBasic Programming/scripting experience in R\n\n\n\nor took an R course NBIS prepared.\n\n\n\n\nDesirable\, but not essential\, skills increasing the output of the course\, include: \n\n\n\n\nSome basic knowledge of biostatistics\n\n\n\nPrevious experience in biomarker-related studies\n\n\n\n\nDue to limited space\, the course can accommodate a maximum of 20 participants. If we receive more applications\, participants will be selected based on selection criteria\, including (but not limited to) correct entry requirements\, motivation to attend the course\, as well as gender and geographical balance.
URL:https://www.scilifelab.se/event/ddls-biomarker-discovery-from-theory-to-real-world-examples/
LOCATION:Air&Fire\, SciLifeLab Stockholm\, Tomtebodavägen 23A\, Solna\, Sweden
CATEGORIES:Course
ORGANIZER;CN="NBIS - National Bioinformatics Infrastructure Sweden":MAILTO:education@nbis.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20231206T090000
DTEND;TZID=Europe/Stockholm:20231206T160000
DTSTAMP:20260404T104101
CREATED:20231025T125024Z
LAST-MODIFIED:20231124T132106Z
UID:10001008-1701853200-1701878400@www.scilifelab.se
SUMMARY:Integrated Structural Biology users meeting
DESCRIPTION:We invite Structural Biologists in Sweden to participate in 2023 Integrated Structural Biology Users meeting\, held in Solna on Dec 6\, 9-16\, see program below.  \n\n\n\nPlease register before November 30 \n\n\n\nregistration\n\n\n\nAll PhD students and post docs within areas such as Cryo-EM\, Structural Proteomics\, NMR\, protein production and other relevant areas are welcome and encouraged to send an abstract and be provided a time slot for a flash talk. If traveling to Solna is needed\, we will pay for travel and one hotel night (December 5). If more applicants than time slots\, we will distribute nationally and from different areas. \n\n\n\nProgram\n\n\n\nISB-User-MeetingDownload
URL:https://www.scilifelab.se/event/isb-users-meeting/
LOCATION:Wangari\, Widerströmska building\,\, Tomtebodavägen 18\, Solna\, Sweden
CATEGORIES:Event
ORGANIZER;CN="Integrated Structural Biology Platform at SciLifeLab":MAILTO:cecilia.persson@nmr.gu.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20231206T100000
DTEND;TZID=Europe/Stockholm:20231206T130000
DTSTAMP:20260404T104101
CREATED:20231120T114459Z
LAST-MODIFIED:20231120T114502Z
UID:10001036-1701856800-1701867600@www.scilifelab.se
SUMMARY:Introducing Molecular Pixelation - Spatial proteomics of single cells by Next Generation Sequencing
DESCRIPTION:We are pleased to invite you to our Spatial Proteomics Seminar organized together with SNP&SEQ Technology Platform/National Genomics Infrastructure (NGI). We will take you beyond the use of flow cytometry and focal microscopy into the intriguing and dynamic world of the cell-surface proteome of single cells through next-generation sequencing. \n\n\n\nFollowing the seminar\, we will serve sandwiches and refreshments. \n\n\n\nDate: Wednesday\, December 6\, 2023Time: 10:00 to 13:00 CETLocation: SciLifeLab Uppsala (Navet)Uppsala Biomedicinska CentrumHusargatan 3\, entrance C11\,752 37 Uppsala \n\n\n\nMolecular Pixelation\n\n\n\nBy simultaneously analyzing changes in the dynamic protein architecture of cellmembranes across 1000s of single cells\, a new chapter has unfolded. This allows us toassess how subtle alterations in the spatial orchestration of proteins impact the immunesystem\, disease outcomes\, and responses to treatment. \n\n\n\nAgenda\n\n\n\n10:00 – 10:05 WelcomeAnnaLotta Schiller\, Pixelgen10:05 – 10:35 Introducing Molecular PixelationSimon Fredriksson\, Pixelgen10:35 – 10:55 Mapping individual drug responses using Molecular PixelationJessica Nordlund\, SciLifeLab\, NGI\, UU10:55 – 11:05 Sequencing single cells at the SciLifeLab National Genomics InfrastructureHenrik Gezelius\, SciLifeLab\, NGI\, UU11:05 – 11:35 Panel discussion including Q&ASimon\, Jessica & Henrik11:35 – 13.00 Sandwiches & Cake \n\n\n\nThe seminar will be accessible in both in-person and virtual formats \n\n\n\nReserve Your Spot\n\n\n\nTo secure your place for the lunch seminar\, register on the link below\, specifying your attendance and lunch preferences. All participants must register including the speakers as well as both in person and virtual attendees \n\n\n\nRegister here
URL:https://www.scilifelab.se/event/introducing-molecular-pixelation-spatial-proteomics-of-single-cells-by-next-generation-sequencing/
LOCATION:Navet\, SciLifeLab Uppsala\, SciLifeLab Uppsala\, BMC C11\, Husargatan 3\, Uppsala\, 75237\, Sweden
CATEGORIES:Event
ORGANIZER;CN="National Genomics Infrastructure (NGI)":MAILTO:support@ngisweden.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20231206T140000
DTEND;TZID=Europe/Stockholm:20231206T163000
DTSTAMP:20260404T104101
CREATED:20231011T092741Z
LAST-MODIFIED:20231129T101253Z
UID:10000998-1701871200-1701880200@www.scilifelab.se
SUMMARY:Joined DanioReadout\, Local SciLifeLab Service Facility and CIV Zebrafish Core Facility information meeting
DESCRIPTION:Zebrafish model focused afternoon with useful information on newly opened\, cutting-edge Uppsala University Zebrafish Core Facility (CIV) and DanioReadout Service Facility (Local SciLifeLab Facility)\, dedicated for researchers interested in zebrafish model and its applications \n\n\n\n\n\n\n\nHost: Aristidis Moustakas (SciLifeLab Scientific Director\, Uppsala University) \n\n\n\nOrganizer: Beata Filipek-Gorniok (DanioReadout Operational Director) \n\n\n\nContact: danioreadout@uu.se \n\n\n\n\n\n\n\nProgram\n\n\n\n14:00WelcomeAristidis Moustakas\, SciLifeLab-Uppsala Scientific Director14:15OpeningKaska Koltowska\, DanioReadout Scientific Director\, and Joakim Holmdal\,CIV Director14:30Zebrafish Core FacilityTiffany Klingström\, zebrafish facility manager14:40Inspirational talk15:10Coffee Break15:30DanioReadout service facilityBeata Filipek-Gorniok and Amin Allalou15:50How do I utilize zebrafish model in my project?short presentations by zebrafish researchers16:30Wrap up\n\n\n\n \n\n\n\n\n\n\n\n\n\nRegistration\n\n\n\nDeadline 2023-11-30 \n\n\n\n\n\nMore about DanioReadout services
URL:https://www.scilifelab.se/event/joined-danioreadout-local-scilifelab-servicefacility-and-civ-zebrafish-core-facility-information-meeting/
LOCATION:Navet\, SciLifeLab Uppsala\, SciLifeLab Uppsala\, BMC C11\, Husargatan 3\, Uppsala\, 75237\, Sweden
CATEGORIES:Event
ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2023/10/Zebrafish.png
ORGANIZER;CN="DanioReadout%2C local SciLifeLab Service Facility at Uppsala University":MAILTO:danioreadout@uu.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20231207T120000
DTEND;TZID=Europe/Stockholm:20231207T130000
DTSTAMP:20260404T104101
CREATED:20230711T121042Z
LAST-MODIFIED:20231127T101044Z
UID:10000939-1701950400-1701954000@www.scilifelab.se
SUMMARY:Campus Solna Seminar Series: Cenk Gurdap
DESCRIPTION:Welcome to join the Campus Solna Seminar Series – an  initiative to promote the fantastic science ongoing at Campus Solna and hopefully forge more internal communication and collaboration between within Campus Solna. The format consists of two 15 min talks (One speaker from the Alpha-building and one from the Gamma-building respectively)\, with an additional 5 min of questions. Presentation of ongoing (unpublished) projects is strongly encouraged. \n\n\n\nThe seminars are held Thursdays 12:00-13:00. You can bring your lunch to the seminar. \n\n\n\nThis week:\n\n\n\n\n\n\nCenk Gurdap\n\n\n\nErdinc Sezgin – gamma 3 \n\n\n\nSpectral biophysical cytometry with smart probes: high-throughput and multi-parametric cell phenotyping \n\n\n\n\n\n\n\n\n\n \n\n\n\n\n\n\nWe have only one talk this week in order to have enough time to go to the Nobel Prize lectures in physiology or medicine at Aula Medica\, Nobels väg 6\, Karolinska institutet\, Campus Solna \n\n\n\nThis seminar series is organized by the PhD & Postdoc Council. For more information about the Council and other events check our page.
URL:https://www.scilifelab.se/event/campus-solna-seminar-series-dec-7-2/
LOCATION:Milkyway SciLifeLab Solna\, Tomtebodavägen 23\, Solna
CATEGORIES:Community
ATTACH;FMTTYPE=image/jpeg:https://www.scilifelab.se/wp-content/uploads/2022/09/IMG_20221103_120135408_HDR-scaled.jpg
ORGANIZER;CN="SciLifeLab Solna PhD & Postdoc Council":MAILTO:phd-council@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20231207T131500
DTEND;TZID=Europe/Stockholm:20231207T140000
DTSTAMP:20260404T104101
CREATED:20231204T135638Z
LAST-MODIFIED:20231204T135723Z
UID:10001058-1701954900-1701957600@www.scilifelab.se
SUMMARY:Multi Omics Data Integration - A translational perspective
DESCRIPTION:The forefront of deriving valuable insights into cellular functions involves the analysis of multi-omics data along with clinical  information. The integration of multi-omics data\, which encompasses information from diverse biomolecular layers\, holds promise for systematically and comprehensively understanding complex biology. Integrated approaches involve combining individual omics data either sequentially or simultaneously\, offering a means to explore the intricate interplay of molecules. This method proves valuable in assessing the flow of information across omics levels\, thereby bridging the gap from genotype to phenotype. Integrative approaches\, through their holistic examination of biological phenomena\, have the potential to enhance prognostic and predictive accuracy for disease phenotypes. Consequently\, they stand to contribute significantly to improved treatment and prevention strategies. In this talk I will show multiple approaches to integrate diverse data types and how we can use them in a translational medicine. \n\n\n\njoin zoom meeting\n\n\n\nAnimesh Acharjee\, PhDAssistant Professor\, Institute of Cancer and Genomic Sciences\, University of Birmingham\, United Kingdom \n\n\n\nBiography \n\n\n\n\n\n\n\nDr. Acharjee’s research interests encompass integrative data analytics\, predictive biomarker discovery\, bioinformatics methods for diagnostics\, and network biology. His multidisciplinary approach reflects his commitment to bridging the gap between computational methodologies and biological insights. Throughout his illustrious career\, Dr. Acharjee has been recognized with numerous fellowships\, including those from the British Council\, the  Dutch Government\, and Newton fellowships. These accolades underscore his dedication to advancing scientific knowledge and his contributions to the fields of bioinformatics\, data analytics\, and biostatistics. Dr. Acharjee’s journey continues to be marked by a relentless pursuit of excellence in research and a commitment to unraveling the intricacies of metabolicdiseases through innovative methodologies.
URL:https://www.scilifelab.se/event/multi-omics-data-integration-a-translational-perspective/
LOCATION:Online event via Zoom
CATEGORIES:Event
ORGANIZER;CN="NBIS - National Bioinformatics Infrastructure Sweden":MAILTO:education@nbis.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20231208T151500
DTEND;TZID=Europe/Stockholm:20231208T161500
DTSTAMP:20260404T104101
CREATED:20231124T084624Z
LAST-MODIFIED:20231124T084626Z
UID:10001040-1702048500-1702052100@www.scilifelab.se
SUMMARY:[The Svedberg seminar] - Engineered Salmonella for drug delivery to solid tumors
DESCRIPTION:Neil Forbes \n\n\n\nProfessor of Chemical EngineeringUniversity of Massachusetts\, USA \n\n\n\n \n\n\n\n\n\n\n\nBio\n\n\n\nNeil Forbes is a Professor of Chemical Engineering at the University of Massachusetts\, Amherst. He is an adjunct member of the Molecular and Cell Biology Program and a member of the Institute for Applied Life Sciences. He received a BS in Chemical Engineering from Case Western Reserve University\, received a PhD in Chemical Engineering from the University of California at Berkeley (with Harvey Blanch and Douglas Clark)\, and was a postdoctoral fellow (with Rakesh Jain) in Radiation Oncology at Harvard Medical School / Massachusetts General Hospital. \n\n\n\nEngineered Salmonella for drug delivery to solid tumors\n\n\n\nAbstract: Engineered bacteria have the potential to overcome the limitations that cause cancer therapies to fail. We have created intracellular delivering Salmonella that accumulate in tumors over healthy tissue and deposit deliver therapeutic payloads directly into the cytoplasm of cancer cells. Bacterial delivery of constitutively active caspase-3 blocks the growth of hepatocellular carcinoma and lung metastases\, and increases survival in mice. Salmonella delivery of an exogenous antigen\, such as from a childhood vaccine\, marks cancer cells as foreign\, and triggers a cytotoxic\, antigen-specific CD8 T cell responses. In mice\, intracellular antigen delivery clears established pancreatic tumors\, increases survival\, and prevents tumor re-implantation by establishing new immunity to intrinsic tumor antigens. This tunable platform could deliver an array of protein drugs to target many hard-to-treat intracellular pathways. As an off-the-shelf therapy\, these bacteria are not dependent on intrinsic tumor characteristics and would be effective for a broad range of cancer patients. \n\n\n\n \n\n\n\n\n\n\n\nHost: Mia Phillipson mia.phillipson@mcb.uu.se\, UU
URL:https://www.scilifelab.se/event/the-svedberg-seminar-neil-forbes/
LOCATION:BMC Room C4:301\, Husargatan 3\, entrance C1\, Uppsala\, Sweden
CATEGORIES:Event
ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2022/02/Picture1-The-Svedberg.png
ORGANIZER;CN="The Svedberg Seminar Series":MAILTO:thesvedberg@scilifelab.uu.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20231211T113000
DTEND;TZID=Europe/Stockholm:20231211T140000
DTSTAMP:20260404T104101
CREATED:20231102T140108Z
LAST-MODIFIED:20231128T134645Z
UID:10001017-1702294200-1702303200@www.scilifelab.se
SUMMARY:Re-Imaging and Re-Imagining Science
DESCRIPTION:As part of the 10th anniversary celebration of the Science & SciLifeLab Prize for young researchers\, we have got  the honour to host a lunch seminar with Shirley Malcom who is senior advisor and director of SEA Change at the American Association for the Advancement of Science (AAAS). For more than 40 years at AAAS she has worked to improve the quality and increase access to education and careers in STEMM for all.  \n\n\n\nFor the SciLifeLab audience\, Shirley will not only give an inspiring lecture. She will also take part of a panel discussion and attend an open discussion/networking session.  \n\n\n\nDo not miss out on this opportunity! \n\n\n\nQuestions to be discussed; \n\n\n\n\nHow we can look critically at what is being done and not being done regarding inclusion?\n\n\n\nHow do we support excellence and what do we want research to look like?\n\n\n\nWhat kind of engagement do we want?\n\n\n\nHow do we bring assets into science and take advantage of people’s differences?\n\n\n\n\n\n\n\n\nRegister\n\n\n\nProgram\n\n\n\n11.30Lunch is served11.55Welcome\, Ylva Engström\, president SciLifeLab board12.00Re-Imaging and Re-Imagining Science\, Shirley Malcom AAAS12.30Panel discussion with Shirley Malcom\, DEI-committe\, Public Engagement\, Code of Conduct and Coaching in Science Initiativechair: Erdinc Sezgin13.05Concluding remarks\, Per Ljungdahl\, director Campus Solna SciLifeLab13.15Coffee\, Exhibition and Open Discussion in Gamma 2 lunchroom\n\n\n\nRead more\n\n\n\nShirley Malcom biography\n\n\n\nSEA Change \n\n\n\nCoaching in Science Initiative \n\n\n\nSciLifeLab Code of Conduct
URL:https://www.scilifelab.se/event/shirley-malcom-lunch-seminar/
LOCATION:Air&Fire\, SciLifeLab Stockholm\, Tomtebodavägen 23A\, Solna\, Sweden
CATEGORIES:Event
ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2023/10/Thumbnail-.png
ORGANIZER;CN="Science/AAAS and SciLifeLab":MAILTO:events@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20231212T090000
DTEND;TZID=Europe/Stockholm:20231212T133000
DTSTAMP:20260404T104101
CREATED:20231005T101319Z
LAST-MODIFIED:20241115T085813Z
UID:10000977-1702371600-1702387800@www.scilifelab.se
SUMMARY:Science & SciLifeLab Prize Symposium 2023
DESCRIPTION:Welcome to the Scientific Symposium presenting the winners of the 2023 Science & SciLifeLab Prize for Young Scientists.  \n\n\n\n\nN.b. This page concerns the Science & SciLifeLab Prize Symposium 2023. To learn about the 2024 event – please click the button below. \n\n\n\nRead about the science & SciLifeLab Prize symposium 2024\n\n\n\n\nScience\, the American Association for the Advancement of Science (AAAS)\, and SciLifeLab joined forces in 2013\, creating the Science & SciLifeLab Prize for Young Scientists to recognize excellence amongst young researchers from around the world. A global Prize aimed at rewarding scientists at an early stage of their careers\, this year celebrating its 10th anniversary. \n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n \n\n\n\nThe Science & SciLifeLab Prize for Young Scientists is an international prize\, awarded annually to four young scientists for outstanding life science research based on a doctoral degree earned in the previous two years.The grand prize-winning essay will be published in Science\, and essays from the three category winners will be published in online issue. \n\n\n\nAll four winners of the Science & SciLifeLab Prize for Young Scientists are invited to Sweden December 9-14 to participate in a unique week filled with events in honor of science. They will have the opportunity to meet with leading scientists in their field of research and create life-long connections to support their careers.  \n\n\n\nThe four winners 2023 are \n\n\n\nZuzanna Kozicka\n\n\n\nMolecular Medicine\, Grand Prize WinnerEssay: Gluing the pieces together: Illuminating the path to degrading troublesome proteins \n\n\n\nRachel Kratofil\n\n\n\nCell and Molecular BiologyEssay: Working up an appetite to promote repair: Immune-derived hunger hormones restore tissue post-infection \n\n\n\nYodai Takei\n\n\n\nGenomics\, Proteomics\, and Systems Biology ApproachesEssay: Imaging nuclear architecture in single cells: Multiplexed imaging technologies uncover precise 3D maps of single nuclei \n\n\n\nJessica Kendall-Bar\n\n\n\nEcology and EnvironmentEssay: Lessons from sleep in the deep: Records of seal sleep at sea reveal extreme sleep duration flexibility \n\n\n\nFor the 10th anniversary of Science and SciLifeLab Prize\, we have invited 2014 year’s category winner Chelsea Wood to give a keynote lecture with the title; Is the world wormier than it used to be? Answers from a new subdiscipline: the historical ecology of parasitism. \n\n\n\nProgram\n\n\n\nProgram flyer_Prize_A4_01 (2)Download\n\n\n\n\n\n\n\nChelsea Wood – Bio\n\n\n\nRead more About the Prize\n\n\n\nPlease contact events@scilifelab.se if you have any questions.
URL:https://www.scilifelab.se/event/science-scilifelab-prize-symposium-2023/
LOCATION:Beijersalen\, Kungl. Vetenskapakademien\, Lilla Frescativägen 4A\, Stockholm\, Sweden
CATEGORIES:Event
ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2023/10/Thumbnail-.png
ORGANIZER;CN="Science/AAAS and SciLifeLab":MAILTO:events@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20231213T133000
DTEND;TZID=Europe/Stockholm:20231213T153000
DTSTAMP:20260404T104101
CREATED:20231124T121410Z
LAST-MODIFIED:20231211T115110Z
UID:10001041-1702474200-1702481400@www.scilifelab.se
SUMMARY:Stronger together; Making space on Team Science for Diverse Career Paths
DESCRIPTION:Science & SciLifeLab Webinar \n\n\n\nBy harnessing different types of expertise and offering several diverse career paths in research\, the definition of what it means to be a life scientist can be broadened and inclusive of a wide array of skill-sets. In this panel discussion\, broadcasted live by Science\, the panel will explore how life scientists can foster a future that maximizes the potential of each researcher and the field overall. \n\n\n\nIn this discussion\, participants will \n\n\n\n\nLearn about how career paths can be diversified and how diverse backgrounds bring value to research excellence\, innovation\, and problem-solving.\n\n\n\nGain insights into why team science is key for multidisciplinary research and collaboration. \n\n\n\nHear how universities and other employers can support individuals pursuing non-traditional career paths in science and build inclusive research communities.\n\n\n\nTake part in shaping the future of research incentives and other drivers of open science.\n\n\n\n\n\n\n\n\nProgram\n\n\n\n\n13.30 Coffee and mingle at IVA conference center \n\n\n\n14.15 Everyone seated in the Wallenberg lecture hall \n\n\n\n14.30 Panel discussion \n\n\n\n15.15 Q&A from the audience \n\n\n\n\nPanel\n\n\n\nAnnika Jenmalm Jensen\, Infrastructure director at SciLifeLab \n\n\n\nChelsea Wood\, Associate professor University of Washington and Science & SciLifeLab Prize Winner 2014 \n\n\n\nDavid Seekell\, Head of Sustainable Investing at Atle and Science & SciLifeLab Prize Winner 2016 \n\n\n\nErik Lindahl\, professor Stockholm University \n\n\n\nModerator\n\n\n\nSacha Vignieri\, Deputy Editor for Research at AAAS/Science magazine \n\n\n\nRegistration
URL:https://www.scilifelab.se/event/stronger-together-making-space-on-team-science-for-diverse-career-paths/
LOCATION:IVA Conference center\, Grev Turegatan 16\, Stockholm
CATEGORIES:Event
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ORGANIZER;CN="Science/AAAS and SciLifeLab":MAILTO:events@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20231213T153000
DTEND;TZID=Europe/Stockholm:20231213T163000
DTSTAMP:20260404T104101
CREATED:20231129T164303Z
LAST-MODIFIED:20231129T164314Z
UID:10001052-1702481400-1702485000@www.scilifelab.se
SUMMARY:Molecular Design of the Kidney Filtration Barrier
DESCRIPTION:Prof. Thomas Benzing\, University Hospital ofCologne\, Germany \n\n\n\nProf. Thomas Benzing will in this talk describe how his group has over the past years made novel discoveries regarding the molecular mechanisms of kidney filtration. Many of these findings are the result of a collaboration with researchers at SciLifeLab/KTH.  \n\n\n\nMost welcome!
URL:https://www.scilifelab.se/event/molecular-design-of-the-kidneyfiltration-barrier/
LOCATION:Air&Fire\, SciLifeLab Stockholm\, Tomtebodavägen 23A\, Solna\, Sweden
CATEGORIES:Event
ORGANIZER;CN="David Unnersj%C3%B6 Jess":MAILTO:david.unnersjojess@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20231215T140000
DTEND;TZID=Europe/Stockholm:20231215T143000
DTSTAMP:20260404T104101
CREATED:20231108T101940Z
LAST-MODIFIED:20231108T102100Z
UID:10001016-1702648800-1702650600@www.scilifelab.se
SUMMARY:CSI Seminar: ‘Moving our Mental Roadblocks’
DESCRIPTION:We are excited to host a new Coaching in Science Initiative (CSI) Seminar titled: ‘Moving our Mental Roadblocks’ \n\n\n\nIn this CSI seminar\, we will raise awareness about mental obstacles and barriers that keep us from the change we want. We will explore Why sustainable change has yet to happen for us\, How we can change that\, and What tools we can use to make it happen! \n\n\n\nThis seminar will be helpful for when we want to make changes in our life\, and yet they don’t happen\, e.g.\, New Year’s resolutions we keep promising ourselves. Starting on that thing\, which we have procrastinated for quite some time. Beginning on a project task early instead of at the last minute. Forming healthy new habits\, such as flossing our teeth or a 30 min walk every day. When we mean to plan rest into our schedule to reduce the stress in our lives\, but – it just does not happen. \n\n\n\nWith our Moving Mental Roadblocks Model\, we will explore why the change we want has yet to happen\, and introduce our mental tool\, the Emotion-Thought-Action (ETA) ladder\, which can be used to enact sustainable change effectively. \n\n\n\nDate: 15/12/2023Time: 14:00 – 14:30Zoom link: https://kth-se.zoom.us/j/69311596145On-site location: Gamma 2 lunch room \n\n\n\nWe will begin with a ~ 20 min talk\, held in Solna and over zoom. Then proceed with a reflection and discussion held only on-site. We encourage other sites to form watch parties\, by listening in together to the talk and then hold their own discussion afterwards. Hopefully seeding many local chapters of CSI. \n\n\n\nTo help facilitate discussion and reflection\, consider the follow starter questions: \n\n\n\nAwareness: where do we experience mental roadblocks in our lives?Analysis: how well do I currently handle mental roadblocks?Alternative: how can we relate to mental roadblocks\, in ourselves and others?Action: how will knowledge of mental roadblocks change my decisions going forward? \n\n\n\nPlease forward this to friends and colleagues! \n\n\n\nYours sincerely\,The CSI Team
URL:https://www.scilifelab.se/event/csi-seminar-moving-our-mental-roadblocks/
LOCATION:Hybrid event in Gamma 2 lunchroom and zoom\, Tomtebodavägen 23 B\, Solna\, 17165\, Sweden
CATEGORIES:Community
ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2023/11/CSI_logo_text-1.png
ORGANIZER;CN="Coaching in Science Initiative (CSI)":MAILTO:sami.saarenpaa@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20231215T140000
DTEND;TZID=Europe/Stockholm:20231215T160000
DTSTAMP:20260404T104101
CREATED:20231208T154608Z
LAST-MODIFIED:20231214T142842Z
UID:10001065-1702648800-1702656000@www.scilifelab.se
SUMMARY:Activity-regulated organization of neuronal protein at the molecular scale
DESCRIPTION:Mini symposium on “Activity-regulated organization of neuronal protein at the molecular scale” \n\n\n\nFor attendees without SciLifeLab access\, we will meet you at the reception of SciLifeLab at 1.50 pm. \n\n\n\n\n\n\n\n \n\n\n\nProgram\n\n\n\n2.00 – 3.00 PM \n\n\n\nMolecular function of Arc in brain plasticity: from hub protein to retroviral-like capsid \n\n\n\nClive Bramham\, University of Bergen\, Norway \n\n\n\n3.00 – 4.00 PM \n\n\n\nDeciphering the spatiotemporal and mechanical regulation of adhesive and cytoskeletal structures at the nanoscale \n\n\n\nGrégory Giannone\, CNRS\, University of Bordeaux\, UMR5297\, Interdisciplinary Institute for Neuroscience\, France \n\n\n\n\n\n\n\n \n\n\n\n \n\n\n\nEvent_Bramham-and-Giannone_locationDownload
URL:https://www.scilifelab.se/event/activity-regulated-organization-of-neuronal-protein-at-the-molecular-scale/
LOCATION:Air&Fire\, SciLifeLab Stockholm\, Tomtebodavägen 23A\, Solna\, Sweden
CATEGORIES:Event
ORGANIZER;CN="Mariline Silva":MAILTO:mariline.silva@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20231218T151500
DTEND;TZID=Europe/Stockholm:20231218T161500
DTSTAMP:20260404T104101
CREATED:20231123T133956Z
LAST-MODIFIED:20231123T134046Z
UID:10001039-1702912500-1702916100@www.scilifelab.se
SUMMARY:[The Svedberg seminar] - Describing tissue pathogenesis with spatial technologies
DESCRIPTION:Sanja Vickovic \n\n\n\nWallenberg Academy Fellow and SciLifeLab FellowDepartment of Immunology\, Genetics and Pathology at Uppsala University \n\n\n\n \n\n\n\n\n\n\n\nBio\n\n\n\nDr. Vickovic is currently a Wallenberg Academy Fellow and SciLifeLab Fellow at the Department of Immunology\, Genetics and Pathology at Uppsala University. Dr. Vickovic received her PhD in Gene Technology from the Royal Institute of Technology in Stockholm. Following her graduate work\, Dr. Vickovic joined the Broad Institute of MIT and Harvard\, Columbia University and the New York Genome Center before continuing in her current role as Assistant Professor at Uppsala University. Dr. Vickovic has extensively worked on pioneering novel spatially resolved transcriptomics and genomics methods that enable massively parallel in situ profiling of intact tissue samples.  \n\n\n\nDescribing tissue pathogenesis with spatial technologies\n\n\n\nAbstract: Spatial and molecular characteristics determine tissue function\, yet high-resolution methods to capture both concurrently are lacking. In recent years\, we developed high-definition spatial transcriptomics and multi-omics technologies\, which captures RNA\, protein information or microbiota from histological tissue sections on spatially barcoded arrays. Today\, I will present how these different technologies were developed and are applied in different biological settings. \n\n\n\n \n\n\n\n\n\n\n\nHost: Ulf Landegren ulf.landegren@igp.uu.se\, UU
URL:https://www.scilifelab.se/event/the-svedberg-seminar-sanja-vickovic/
LOCATION:BMC Room C8:301\, Husargatan 3\, Uppsala\, Sweden
CATEGORIES:Event
ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2022/02/Picture1-The-Svedberg.png
ORGANIZER;CN="The Svedberg Seminar Series":MAILTO:thesvedberg@scilifelab.uu.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20240112T110000
DTEND;TZID=Europe/Stockholm:20240112T120000
DTSTAMP:20260404T104101
CREATED:20231206T165224Z
LAST-MODIFIED:20231207T151005Z
UID:10001062-1705057200-1705060800@www.scilifelab.se
SUMMARY:Calls for new project support in chemical biology and drug discovery
DESCRIPTION:The chemical biology unit (CBCS) and the Drug discovery and development (DDD) platform at SciLifeLab have calls out for projects – see https://anubis.scilifelab.se \n\n\n\nCBCS is looking for projects in Chemical Biology which includes assay development for small molecule screening and profiling\, as well as enabling chemistry. For more information\, please visit www.cbcs.se. \n\n\n\nThe DDD platform has a call looking for new project proposals for drug discovery. All therapeutic modalities that can be developed in collaboration with the DDD platform at SciLifeLab are of interest\, including small molecules\, antibodies\, oligonucleotides and new modalities. \n\n\n\nSome users and projects are at the intersection between chemical biology and drug discovery. We believe this webinar will help you to find out were your project fits in best. \n\n\n\nsign up here\n\n\n\nProgram: \n\n\n\n1. Presentation of CBCS offerings2. Presentation of the DDDp offerings3. Q&A \n\n\n\nOrganizer: the Chemical Biology Consortium Sweden and the Drug Discovery & Development platform
URL:https://www.scilifelab.se/event/calls-for-new-project-support-in-chemical-biology-and-drug-discovery-2/
LOCATION:Online event via Zoom
CATEGORIES:Event
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20240112T130000
DTEND;TZID=Europe/Stockholm:20240112T140000
DTSTAMP:20260404T104101
CREATED:20231220T101638Z
LAST-MODIFIED:20240112T114300Z
UID:10001072-1705064400-1705068000@www.scilifelab.se
SUMMARY:DDLS Data Science Node information
DESCRIPTION:Welcome to a brief update on the status of the Data Science Node (DSN) for Cell and Molecular Biology (CMB) and information about a community survey that will open after this meeting. Data Science Node management\, Sverker Holmgren and Thomas Svensson will describe the survey and answer questions. The event is open to everyone. Please register to get the Zoom link in your mailbox.  You can pre-send input or questions regarding the DSN in CMB to Sverker and Thomas in the registration form. \n\n\n\n\n\n\n\n\n \n\n\n\nRegistration\n\n\n\n\n\nSurvey\n\n\n\nLink to Survey\n\n\n\n\nRead more about DDLS Data Science Nodes
URL:https://www.scilifelab.se/event/ddls-data-science-node-information/
CATEGORIES:Event
ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2023/03/CMB_web.png
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20240115T150000
DTEND;TZID=Europe/Stockholm:20240115T160000
DTSTAMP:20260404T104101
CREATED:20231227T115931Z
LAST-MODIFIED:20231227T120134Z
UID:10001077-1705330800-1705334400@www.scilifelab.se
SUMMARY:Genomics\, Imaging and AI - three technologies which are changing biological research and clinical practice
DESCRIPTION:Prof. Ewan Birney is Deputy Director General of EMBL and Joint Director of EMBL-EBI. Prof. Birney will come to Stockholm to give a talk on Jan 15 from 15:00 to 16:00 at Biomedicum\, KI Campus Solna. Come and listen to an exciting talk about the next steps in medical research! \n\n\n\nJan 15 at 15:00 – 16:00 \n\n\n\nEva & Georg Klein Conference hall\, Biomedicum\, Solnavägen 9 \n\n\n\nWelcome! \n\n\n\nProf. Ewan Birney flyer Jan 15Download flyer
URL:https://www.scilifelab.se/event/genomics-imaging-and-ai-three-technologies-which-are-changing-biological-research-and-clinical-practice/
LOCATION:Eva & Georg Klein lecture hall\, Biomedicum\, Karolinska Institutet\, Solnavägen 9\, Solna\, Solnavägen 9\, Solna
CATEGORIES:Event
ATTACH;FMTTYPE=image/jpeg:https://www.scilifelab.se/wp-content/uploads/2022/09/SciLifeLab_EMBL-e1678190893272.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20240118T090000
DTEND;TZID=Europe/Stockholm:20240118T150000
DTSTAMP:20260404T104101
CREATED:20231208T120428Z
LAST-MODIFIED:20231208T120459Z
UID:10001064-1705568400-1705590000@www.scilifelab.se
SUMMARY:Opening of the Lightsheet 7 at the Centre for Cellular Imaging
DESCRIPTION:The Centre for Cellular Imaging is pleased to announce the purchase and installation of the Lightsheet 7 fluorescence microscopemicroscope. \n\n\n\nLight sheet fluorescence microscopy (LSFM) uses a thin sheet of light to excite only fluorophores within the focal volume. It is ideal for fast and gentle imaging of whole living model organisms\, tissues\, and cells as they develop – over extended periods of time. Furthermore\, the Lightsheet 7 is designed to handle large optically cleared specimens with subcellular resolution. Dedicated optics\, sample chambers\, and holders allow adaption to the refractive index of the chosen clearing method. \n\n\n\nThe Lightsheet 7 is now installed at the Centre for Cellular Imaging and to celebrate this we will host an “Opening Day” with seminars and demos\, where you can learn about this technology and other types of equipment available at the CCI.Please join us on January 18th to explore what is possible with this new instrumentation! \n\n\n\nRegistration deadline: January 11th \n\n\n\nregistration
URL:https://www.scilifelab.se/event/opening-of-the-lightsheet-7-at-the-centre-for-cellular-imaging/
LOCATION:Birgit Thilander Lecture Hall\, Medicinaregatan 3\, Göteborg
CATEGORIES:Event
ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2023/12/banner-ls7.png
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20240118T120000
DTEND;TZID=Europe/Stockholm:20240118T130000
DTSTAMP:20260404T104101
CREATED:20230711T120215Z
LAST-MODIFIED:20240108T102321Z
UID:10000938-1705579200-1705582800@www.scilifelab.se
SUMMARY:Campus Solna Seminar Series: Samu Himanen & Donal Barrett
DESCRIPTION:Welcome to join the Campus Solna Seminar Series – an  initiative to promote the fantastic science ongoing at Campus Solna and hopefully forge more internal communication and collaboration between within Campus Solna. The format consists of two 15 min talks (One speaker from the Alpha-building and one from the Gamma-building respectively)\, with an additional 5 min of questions. Presentation of ongoing (unpublished) projects is strongly encouraged. \n\n\n\nThe seminars are held Thursdays 12:00-13:00. You can bring your lunch to the seminar. \n\n\n\nThis week:\n\n\n\n\n\n\nSamu Himanen\n\n\n\nAnniina Vihervaara – alpha 3 \n\n\n\nTracking Pol II modifications and nascent trascription by Pol I-III complexes at single-nucleotide resolution \n\n\n\n\n\nDonal Barrett\n\n\n\nVicent Pelechano – gamma 5 \n\n\n\nRapid electronic quantification of clinical pathogens using novel DNA nanoballs \n\n\n\n\n\n\nThis seminar series is organized by the PhD & Postdoc Council. For more information about the Council and other events check our page.
URL:https://www.scilifelab.se/event/campus-solna-seminar-series-dec-7/
LOCATION:Air&Fire\, SciLifeLab Stockholm\, Tomtebodavägen 23A\, Solna\, Sweden
CATEGORIES:Community
ATTACH;FMTTYPE=image/jpeg:https://www.scilifelab.se/wp-content/uploads/2022/09/IMG_20221103_123412496_HDR2-scaled.jpg
ORGANIZER;CN="SciLifeLab Solna PhD & Postdoc Council":MAILTO:phd-council@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20240119T100000
DTEND;TZID=Europe/Stockholm:20240119T110000
DTSTAMP:20260404T104101
CREATED:20240115T114456Z
LAST-MODIFIED:20240116T094413Z
UID:10001107-1705658400-1705662000@www.scilifelab.se
SUMMARY:AICell Lab -- Building AI Systems for Human Cell Modeling and Simulation
DESCRIPTION:NBIS\, Scilifelab’s Bioinformatics platform\, arranges an open AI and IO Seminar Series aimed at knowledge-sharing about Artificial Intelligence and Integrative Omics (AI & IO) analysis and applications in the Life Science community. The seminar series is open to everyone. The seminar is run over Zoom on the third Friday of the month during academic terms\, typically between 10 and 11 am\, with ca. 45 min long presentation and 15 min discussion. \n\n\n\nFor further info\, please see this website. \n\n\n\n \n\n\n\n\n\n\n\nAICell Lab — Building AI Systems for Human Cell Modeling and Simulation\n\n\n\nWei Ouyang\, DDLS fellow\, Royal Institute of Technology\, KTH \n\n\n\nThe AICell Lab is a newly founded group by the Data-Driven Life Science fellows program at the department of applied physics at KTH. The lab is dedicated to building artificial intelligence (AI) systems for cell and molecular biology\, with the ultimate goal of modeling the human cell and building human cell simulators using powerful AI models. The lab’s approach to this grand challenge involves not only innovations in data analysis and modeling\, but also in data generation\, specifically the creation of an automated imaging farm equipped with multiple microscopes\, robotic arms\, liquid handling robots\, and automatic incubators. The lab’s AI software infrastructure enables real-time augmentation of microscopy views\, generating artificial labels and annotations\, and optimizing experimental conditions to capture rare events in live cells. The long-term goal of the AICell Lab is to create large-scale whole human cell models trained on existing multi-omics datasets and new data generated by the imaging farm\, which have the potential to revolutionize in-silico cell experimentation and drug discovery while contributing to a holistic and systematic understanding of the human cell. \n\n\n\nClick here to join zoom conference
URL:https://www.scilifelab.se/event/ai-approach-to-cell-and-molecular-biology/
LOCATION:Online event via Zoom
CATEGORIES:Event
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20240119T130000
DTEND;TZID=Europe/Stockholm:20240119T140000
DTSTAMP:20260404T104101
CREATED:20240110T132404Z
LAST-MODIFIED:20240110T132648Z
UID:10001102-1705669200-1705672800@www.scilifelab.se
SUMMARY:Webinar: SiMSen-seq\, new tool for ultrasensitive detection of circulating tumor DNA in childhood malignancies
DESCRIPTION:Next up on the Clinical Genomics Webinar Series: \n\n\n\nClinical Genomics Gothenburg has organised an exciting new webinar to be held on Friday 19th January 2024 at 13:00 on Zoom (click here to join). \n\n\n\nIn the seminar: “SiMSen-seq: A new tool for ultrasensitive detection of circulating tumor DNA in childhood malignancies”\, focuses on ultrasensitive sequencing\, Martin Dalin\, sheds light on a clinical application of SiMSen-seq. \n\n\n\nIf you have questions\, please contact the host Marcela Davila (marcela.davila@gu.se) or CG vicePCO Esther González-Padilla (esther.gonzalez-padilla@scilifelab.se). \n\n\n\nEveryone is welcome so feel free to spread the details with anyone who might be interested. \n\n\n\nMartin Dalin is a professor at Sahlgrenska Center for Cancer Research\, Wallenberg Centre for Molecular and Translational Medicine\, the Institute of Clinical Sciences\, Sahlgrenska Academy at University of Gothenburg
URL:https://www.scilifelab.se/event/webinar-simsen-seq-new-tool-for-ultrasensitive-detection-of-circulating-tumor-dna-in-childhood-malignancies/
LOCATION:Online event via Zoom
CATEGORIES:Event
ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2024/01/SiMSen-sec_webinar.png
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20240122T151500
DTEND;TZID=Europe/Stockholm:20240122T161500
DTSTAMP:20260404T104101
CREATED:20231211T083458Z
LAST-MODIFIED:20240110T165531Z
UID:10001067-1705936500-1705940100@www.scilifelab.se
SUMMARY:[The Svedberg seminar] - Nucleosomes for all: histone-based chromatin in noneukaryotic organisms
DESCRIPTION:Karolin Luger \n\n\n\nProfessor University of Colorado\, USA \n\n\n\nPLEASE NOTE: This seminar will be given both in Uppsala\, BMC at January 22:nd and additionally in Solna at January 23\, 14:00\, George and Eva Klein\, Biomedicum\, Solnavägen 9\, Stockholm \n\n\n\n\n\n\n\nBio\n\n\n\nKarolin Luger is a distinguished professor and the Jennie Smoly Caruthers Endowed Chair of Biochemistry at the University of Colorado in Boulder\, and an investigator for the Howard Hughes Medical Institute. She is recognized for her work on nucleosome structure and interacting proteins. The lab also studies the DNA damage recognition protein PARP1 and its interactions with chromatin\, with the aim of developing novel PARP inhibitors for cancer therapy. The group explores histone-based DNA organization in non-eukaryotic organisms\, to gain insight into the evolutionary origin of the nucleosome. \n\n\n\nLuger was born in Austria and obtained a degree in Biochemistry from the University of Innsbruck. She obtained her Ph.D. in biophysics from the Biocenter Basel\, then moved to a postdoc at the ETH Zuerich in 1990. She started her independent career at Colorado State University in 1999\, and in 2015 moved to the University of Colorado at Boulder. She is a fellow of the Biophysical Society\, a member of the National Academy of Science; the American Academy of Arts and Science; and EMBO. In 2023\, she was awarded the World Laureate Association (WLA) Prize in Life Science or Medicine for her groundbreaking work on nucleosome structure. \n\n\n\n \n\n\n\nNucleosomes for all: histone-based chromatin in noneukaryotic organisms\n\n\n\nAll eukaryotes organize their DNA into nucleosomes\, consisting of an octamer of the four core histone proteins H2A\, H2B\, H3\, and H4\, around which 147 base pairs of DNA are wrapped in two tight superhelical turns. Histones were an early acquisition in eukaryogenesis that allowed for massive genome expansion\, a prerequisite for the complexity observed in modern-day eukaryotes. Histones are the targets of epigenetic modifications through the incorporation of histone variants and histone post-translational modifications\, and require elaborate assembly and remodeling machinery for gene regulation. Who provided the chromatin starter kit to the early eukaryote? Many archaea organize their genomes with single\, non-diversified histones that form slinky-like structures\, without the requirement for additional machinery to assemble and disassemble nucleosomal structures.  A subclass of giant viruses (ancient double-stranded DNA viruses that infect amoebae) also encode their own histones\, and these form meta-stable nucleosome-like structures with distinct features. Unexpectedly\, we recently discovered that histones are sporadically present in the bacterial domain of life. In a stunning reversal of ‘histone logic’\, these small histones encase straight DNA rather than wrapping it around them.  As such\, histones are no longer a prerogative of eukaryotes but appear to be an ancient DNA packaging principle that has adapted to varying constraints in different domains of life. \n\n\n\n \n\n\n\n\n\n\n\nHost: Sebastian Deindl sebastian.deindl@icm.uu.se UU\, Simon Elsässer simon.elsasser@scilifelab.se\, KI
URL:https://www.scilifelab.se/event/the-svedberg-seminar-karolin-luger/
LOCATION:BMC Trippelrummet\, Husargatan 3\, entrance C11\, Uppsala\, Sweden
CATEGORIES:Event
ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2022/02/Picture1-The-Svedberg.png
ORGANIZER;CN="The Svedberg Seminar Series":MAILTO:thesvedberg@scilifelab.uu.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20240123T140000
DTEND;TZID=Europe/Stockholm:20240123T150000
DTSTAMP:20260404T104101
CREATED:20240116T142015Z
LAST-MODIFIED:20240122T170453Z
UID:10001111-1706018400-1706022000@www.scilifelab.se
SUMMARY:Spotlight seminar - Nucleosomes for all: histone-based chromatin in noneukaryotic organisms
DESCRIPTION:Karolin Luger\n\n\n\nUniversity of Colorado\, USA \n\n\n\n\n\n\n\nPLEASE NOTE: This seminar will be given both in Uppsala\, BMC Trippelrummet at January 22 15.15-16.15 and additionally in Solna at January 23\, 14:00\, George and Eva Klein\, Biomedicum\, Solnavägen 9\, Stockholm \n\n\n\nBio\n\n\n\nKarolin Luger is a distinguished professor and the Jennie Smoly Caruthers Endowed Chair of Biochemistry at the University of Colorado in Boulder\, and an investigator for the Howard Hughes Medical Institute. She is recognized for her work on nucleosome structure and interacting proteins. The lab also studies the DNA damage recognition protein PARP1 and its interactions with chromatin\, with the aim of developing novel PARP inhibitors for cancer therapy. The group explores histone-based DNA organization in non-eukaryotic organisms\, to gain insight into the evolutionary origin of the nucleosome. \n\n\n\nLuger was born in Austria and obtained a degree in Biochemistry from the University of Innsbruck. She obtained her Ph.D. in biophysics from the Biocenter Basel\, then moved to a postdoc at the ETH Zuerich in 1990. She started her independent career at Colorado State University in 1999\, and in 2015 moved to the University of Colorado at Boulder. She is a fellow of the Biophysical Society\, a member of the National Academy of Science; the American Academy of Arts and Science; and EMBO. In 2023\, she was awarded the World Laureate Association (WLA) Prize in Life Science or Medicine for her groundbreaking work on nucleosome structure. \n\n\n\nNucleosomes for all: histone-based chromatin in noneukaryotic organisms\n\n\n\nAll eukaryotes organize their DNA into nucleosomes\, consisting of an octamer of the four core histone proteins H2A\, H2B\, H3\, and H4\, around which 147 base pairs of DNA are wrapped in two tight superhelical turns. Histones were an early acquisition in eukaryogenesis that allowed for massive genome expansion\, a prerequisite for the complexity observed in modern-day eukaryotes. Histones are the targets of epigenetic modifications through the incorporation of histone variants and histone post-translational modifications\, and require elaborate assembly and remodeling machinery for gene regulation. Who provided the chromatin starter kit to the early eukaryote? Many archaea organize their genomes with single\, non-diversified histones that form slinky-like structures\, without the requirement for additional machinery to assemble and disassemble nucleosomal structures.  A subclass of giant viruses (ancient double-stranded DNA viruses that infect amoebae) also encode their own histones\, and these form meta-stable nucleosome-like structures with distinct features. Unexpectedly\, we recently discovered that histones are sporadically present in the bacterial domain of life. In a stunning reversal of ‘histone logic’\, these small histones encase straight DNA rather than wrapping it around them.  As such\, histones are no longer a prerogative of eukaryotes but appear to be an ancient DNA packaging principle that has adapted to varying constraints in different domains of life. \n\n\n\nHost: Simon Elsässer simon.elsasser@scilifelab.se\, KI and Sebastian Deindl sebastian.deindl@icm.uu.se UU
URL:https://www.scilifelab.se/event/spotlight-seminar-nucleosomes-for-all-histone-based-chromatin-in-noneukaryotic-organisms/
LOCATION:Eva & Georg Klein lecture hall\, Biomedicum\, Karolinska Institutet\, Solnavägen 9\, Solna\, Solnavägen 9\, Solna
CATEGORIES:Event
ATTACH;FMTTYPE=image/jpeg:https://www.scilifelab.se/wp-content/uploads/2023/10/Campus-solna-seminar-picture.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20240125T120000
DTEND;TZID=Europe/Stockholm:20240125T130000
DTSTAMP:20260404T104101
CREATED:20240102T093939Z
LAST-MODIFIED:20240111T085934Z
UID:10001078-1706184000-1706187600@www.scilifelab.se
SUMMARY:Campus Solna Seminar Series: João Varela & Björn Hammarström
DESCRIPTION:Welcome to join the Campus Solna Seminar Series – an  initiative to promote the fantastic science ongoing at Campus Solna and hopefully forge more internal communication and collaboration between within Campus Solna. The format consists of two 15 min talks (One speaker from the Alpha-building and one from the Gamma-building respectively)\, with an additional 5 min of questions. Presentation of ongoing (unpublished) projects is strongly encouraged. \n\n\n\nThe seminars are held Thursdays 12:00-13:00. You can bring your lunch to the seminar. \n\n\n\nThis week:\n\n\n\n\n\n\nJoão Varela\n\n\n\nAman Russon – alpha 4 \n\n\n\nFiber-based approach to Cancer Cell-picking for Diagnostric Applications \n\n\n\n\n\nBjörn Hammarström\n\n\n\nMartin Viklund – gamma 3 \n\n\n\n \n\n\n\n\n\n\nThis seminar series is organized by the PhD & Postdoc Council. For more information about the Council and other events check our page.
URL:https://www.scilifelab.se/event/campus-solna-seminar-series-joao-varela-bjorn-hammarstrom/
LOCATION:Air&Fire\, SciLifeLab Stockholm\, Tomtebodavägen 23A\, Solna\, Sweden
CATEGORIES:Community
ATTACH;FMTTYPE=image/jpeg:https://www.scilifelab.se/wp-content/uploads/2022/09/IMG_20221103_120135408_HDR-scaled.jpg
ORGANIZER;CN="SciLifeLab Solna PhD & Postdoc Council":MAILTO:phd-council@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20240125T120000
DTEND;TZID=Europe/Stockholm:20240125T133000
DTSTAMP:20260404T104101
CREATED:20231221T131449Z
LAST-MODIFIED:20240125T112047Z
UID:10001076-1706184000-1706189400@www.scilifelab.se
SUMMARY:Drug discovery & development possibilities for industry at SciLifeLab NMR unit and MAX IV BioMAX beamline
DESCRIPTION:Welcome to this webinar directed to life science companies and researchers in drug discovery and development. Learn about support available from Swedish research infrastructures. Gain insights from companies that have used the NMR units at SciLifeLab and the BioMAX beamline at MAX IV Laboratory  for their drug discovery and development projects. \n\n\n\nBreak out rooms for specific questions on each technique will be arranged in the end. \n\n\n\nIn collaboration with InfraLife partners SwedenBIO and The Swedish Association of the Pharmaceutical Industry\, LIF. \n\n\n\nTopics and Speakers\n\n\n\nThe BioMAX beamline in drug discoveryAna Gonzales\, MAX IV \n\n\n\nLeveraging X-ray crystallographic data through advanced infrastructuresBjörn Walse CEO\, SARomics Biostructures \n\n\n\nSciLifeLab NMR in drug discovery & developmentCecilia Persson\, ISB Platform coordinator\, SciLifeLab NMR Centre \n\n\n\nQuality testing of biosimilars using NMRCarl Diehl\, Manager of NMR Services\, SARomics Biostructures \n\n\n\nBreak out rooms for further questions and discussionNMR-break out room with Cecilia P and Carl DBioMAX-break out room with Ana G and Björn W \n\n\n\n \n\n\n\nUseful Links\n\n\n\n\nIndustry case: The Swedish NMR-Centre\, part of SciLifeLab – a Crucial Asset for SARomics Biostructures’ Drug Discovery ServicesR Centre\n\n\n\nSwedish NMR Centre\n\n\n\nBiomax at MAX IV Laboratory\n\n\n\nInfraLife\n\n\n\n\n\n\n\n\nregistration
URL:https://www.scilifelab.se/event/drug-discovery-development-possibilities-for-industry-at-scilifelab-and-max-iv/
LOCATION:Online event via Zoom
CATEGORIES:Event
ATTACH;FMTTYPE=image/jpeg:https://www.scilifelab.se/wp-content/uploads/2021/05/Infralife-square.jpg
ORGANIZER;CN="InfraLife":MAILTO:events@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20240126T080000
DTEND;TZID=Europe/Stockholm:20240126T190000
DTSTAMP:20260404T104101
CREATED:20231129T153110Z
LAST-MODIFIED:20240117T102834Z
UID:10001051-1706256000-1706295600@www.scilifelab.se
SUMMARY:Complex Diseases Conference
DESCRIPTION:Precision health around the corner – deciphering complex diseases \n\n\n\nIt is our pleasure to announce the second conference for Genomic Medicine Sweden (GMS) – Complex Diseases. The event aims at bringing together researchers and clinicians to accelerate the clinical implementation of precision medicine of complex diseases. The meeting is open to everyone with professional interest in the field. \n\n\n\nRead more\n\n\n\nRegistration\n\n\n\nProgram\n\n\n\nGMS-Complex-diseases-conference-1Download\n\n\n\n \n\n\n\nDate: January 26th\, 2024Time: 9 am – 7 pmWhere: Wenner-Gren Center\, Stockholm
URL:https://www.scilifelab.se/event/complex-diseases-conference/
LOCATION:Wenner-Gren Center\, Sveavägen 166\, Stockholm\, 113 46\, Sweden
CATEGORIES:Event
ATTACH;FMTTYPE=image/jpeg:https://www.scilifelab.se/wp-content/uploads/2023/11/GMS.jpg
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BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20240126T150000
DTEND;TZID=Europe/Stockholm:20240126T160000
DTSTAMP:20260404T104101
CREATED:20240112T110052Z
LAST-MODIFIED:20240112T110206Z
UID:10001105-1706281200-1706284800@www.scilifelab.se
SUMMARY:From human population variation to ligand binding sites via SARS-CoV-2
DESCRIPTION:Talk by\n\n\n\nGeoff Barton\, Professor of Bioinformatics and Head of Division of Computational Biology School of Life Sciences University of Dundee\, Dundee\, Scotland\, UK. \n\n\n\nTitle\n\n\n\nFrom human population variation to ligand binding sites via SARS-CoV-2 \n\n\n\nAbstract\n\n\n\nIn this talk I will present an analysis that compares publicly available variation data for human with variation seen across all available protein sequences regardless of species.  The analysis confirms patterns of variation in human are consistent with protein structural features (e.g. a-helix and b-strand) but highlights structurally and functionally important sites in around 15\,000 human protein domains that are not found by conventional sequence analysis methods. The identified sites are enriched in disease-associated variants\, ligand binding residues and protein-protein interaction sites. \n\n\n\nI will explain the method and illustrate the new analysis with examples including the Nuclear Receptor Ligand Binding Domains and G-protein coupled receptors (GPCRs) which are important therapeutic targets. \n\n\n\nThe study makes heavy use of the popular Jalview (www.jalview.org) sequence analysis program developed since 1996 in my group\, so I will also give a brief update on Jalview’s new features for exploring nsSNPs on alignments and three-dimensional structures.  \n\n\n\nA preprint describing some aspects of this work was deposited on bioRxiv MacGowan et al\, 2017: https://doi.org/10.1101/127050) and a specific application to the Ankyrin Repeats was published: Utgés et al\, 2021 https://doi.org/10.1371/journal.pcbi.1009335  More recent work applies the methods to ligand binding sites: Utgés et al\, 2023:  https://www.researchsquare.com/article/rs-3185838/v1 \n\n\n\nI will also give a brief summary of our work on SARS-CoV-2 that builds on our experience of analysing human population data MacGowan et al\, 2020: https://doi.org/10.1101/2020.05.03.074781\,MacGowan et al\, 2022:  https://doi.org/10.1371/journal.pcbi.1009922\, Barton\, M. I. et al\, 2021: https://doi.org/10.1101/2021.05.18.444646 \n\n\n\nRead more
URL:https://www.scilifelab.se/event/from-human-population-variation-to-ligand-binding-sites-via-sars-cov-2/
LOCATION:Air&Fire\, SciLifeLab Stockholm\, Tomtebodavägen 23A\, Solna\, Sweden
CATEGORIES:Event
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20240129T151500
DTEND;TZID=Europe/Stockholm:20240129T161500
DTSTAMP:20260404T104101
CREATED:20240109T110554Z
LAST-MODIFIED:20240109T135707Z
UID:10001101-1706541300-1706544900@www.scilifelab.se
SUMMARY:[The Svedberg seminar] - The Impossibility of Whales: somatic evolution across the tree of life
DESCRIPTION:Alex Cagan \n\n\n\nAssistant ProfessorUniversity of Cambridge\, UK \n\n\n\n \n\n\n\n\n\n\n\nBio\n\n\n\nAlex Cagan is an Assistant Professor at the Departments of Genetics\, Pathology and Veterinary Medicine at the University of Cambridge and affiliate of the Programme for Cancer\, Ageing and Somatic Mutation at the Wellcome Sanger Institute. He obtained his PhD in comparative genomics with Svante Pääbo at the Max Planck Institute for Evolutionary Anthropology before doing a post-doc with Inigo Martincorena at the Wellcome Sanger Institute to develop methods to study somatic evolution. His work focuses on the development and application of methods to study somatic evolutionary processes across species to gain insights into cancer\, ageing and environmental monitoring. Alex is also enthusiastic about science illustration and communication. \n\n\n\n \n\n\n\nThe Impossibility of Whales: somatic evolution across the tree of life\n\n\n\nSomatic mutations accumulate in cells throughout life. They underpin the development of cancer and may contribute to ageing. Studying these mutations in healthy tissues has been challenging due to the difficulty of detecting mutations present in single cells or small clones in a tissue. Recent technical advances are enabling their study\, revealing how cells accumulate mutations at different rates and how clonal expansions of mutant cells colonise tissues. Yet little is known about how these processes operate in non-human species. We performed whole-genome sequencing of 208 intestinal crypts from 56 individuals to study the landscape of somatic mutation across 16 mammalian species. This comparative analysis of somatic mutagenesis shed light on the diversity of mutagenic processes across species\, and on long-standing questions regarding the evolution of somatic mutation rates and their role in cancer and ageing. We are now developing methods to enable the study of somatic evolution across any cell type in any species. These approaches aim to provide insights into the evolutionary origin of somatic mutational processes and the mechanisms that underlie cancer resistance in species where cancer is rare.   \n\n\n\n \n\n\n\n\n\n\n\nHost: Matthew Webster matthew.webster@imbim.uu.se\, UU
URL:https://www.scilifelab.se/event/the-svedberg-seminar-alex-cagan/
LOCATION:BMC Room C8:301\, Husargatan 3\, Uppsala\, Sweden
CATEGORIES:Event
ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2022/02/Picture1-The-Svedberg.png
ORGANIZER;CN="The Svedberg Seminar Series":MAILTO:thesvedberg@scilifelab.uu.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20240201T120000
DTEND;TZID=Europe/Stockholm:20240201T130000
DTSTAMP:20260404T104101
CREATED:20240102T094048Z
LAST-MODIFIED:20240115T094340Z
UID:10001079-1706788800-1706792400@www.scilifelab.se
SUMMARY:Campus Solna Seminar Series: Meng Yuan & Claudia Alleva
DESCRIPTION:Welcome to join the Campus Solna Seminar Series – an  initiative to promote the fantastic science ongoing at Campus Solna and hopefully forge more internal communication and collaboration between within Campus Solna. The format consists of two 15 min talks (One speaker from the Alpha-building and one from the Gamma-building respectively)\, with an additional 5 min of questions. Presentation of ongoing (unpublished) projects is strongly encouraged. \n\n\n\nThe seminars are held Thursdays 12:00-13:00. You can bring your lunch to the seminar. \n\n\n\nThis week:\n\n\n\n\n\n\nMeng Yuan\n\n\n\nAdil Mardinoglu – alpha 6 \n\n\n\nDiscovering drug candidates for pancreatic ductal adenocarcinoma with a system biology-based drug repositioning approach \n\n\n\n\n\nClaudia Alleva\n\n\n\nLucie Delemotte – gamma 3 \n\n\n\nTowards a computational characterization of proton coupling in a bacterial sugar transporter \n\n\n\n\n\n\nThis seminar series is organized by the PhD & Postdoc Council. For more information about the Council and other events check our page.
URL:https://www.scilifelab.se/event/campus-solna-seminar-series-meng-yuan-claudia-alleva/
LOCATION:Air&Fire\, SciLifeLab Stockholm\, Tomtebodavägen 23A\, Solna\, Sweden
CATEGORIES:Community
ATTACH;FMTTYPE=image/jpeg:https://www.scilifelab.se/wp-content/uploads/2022/09/IMG_20221103_124630107_HDR-scaled.jpg
ORGANIZER;CN="SciLifeLab Solna PhD & Postdoc Council":MAILTO:phd-council@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20240202T100000
DTEND;TZID=Europe/Stockholm:20240202T110000
DTSTAMP:20260404T104101
CREATED:20231207T150409Z
LAST-MODIFIED:20240122T160625Z
UID:10001063-1706868000-1706871600@www.scilifelab.se
SUMMARY:Practical intro to GPU programming in Python and Julia
DESCRIPTION:This event is part of the Tools for AI/ML research in life sciences event series arranged by the SciLifeLab Data Centre. This webinar is organized in collaboration with the EuroHPC National Competence Centre Sweden (ENCCS) as well as the National Supercomputer Centre\, LiU. \n\n\n\nTitle: Practical intro to GPU programming in Python & Julia \n\n\n\nSpeaker: Yonglei Wang\, PhD\, Research Software Engineer and HPC application expert\, ENCCS \n\n\n\nWhere and when: February 2\, 2024 at 10:00-11:00 Stockholm time\, online. Registration is open till February 2 at 9:00.  \n\n\n\nAbstract: Availability of Graphics Processing Units (GPUs) has transformed the way we work with machine learning and data science challenges in life sciences. The parallel processing capabilities of GPUs have allowed training of ever more complex models\, allowing researchers to analyze large biological datasets with unprecedented efficiency. However\, in order to make use of the potential that GPUs offer we need be able to write fitting machine learning model code and analysis pipelines. In this webinar ENCCS will present some practical tips about what to keep in mind and how to optimize your code when running analyses on GPU hardware. This webinar will be most useful to researchers who already work with large datasets and would like to improve their understanding of how to work with GPUs. At the end\, the participants will also be given an overview of online materials and in-person courses where researchers can learn about this topic in depth.  \n\n\n\nRegister to join the event\n\n\n\nMore about the event series: \n\n\n\nTools for AI/ML research in life sciences is an event series by the SciLifeLab Data Centre aimed at life science researchers who use machine learning methods in their work. The goal of the events in this series is to provide introductions to different tools for ML research but also to foster discussions around our practices and how they can be improved. The events takes place virtually (over Zoom) and are open to researchers in Sweden and beyond. Each event is scheduled for 60 minutes\, consisting of a talk and an extended discussion. Follow the page of the event series to learn about future seminars. \n\n\n\nFor questions about the events please contact the organizing team by emailing  serve@scilifelab.se  \n\n\n\n \n\n\n\nScientific lead: Prof. Ola Spjuth\, SciLifeLab Data Centre and Uppsala University and DDLS \n\n\n\nContact information: serve@scilifelab.se
URL:https://www.scilifelab.se/event/practical-intro-to-gpu-programming-in-python-and-julia/
LOCATION:Online event via Zoom
CATEGORIES:Event
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