BEGIN:VCALENDAR VERSION:2.0 PRODID:-//SciLifeLab - ECPv6.15.18//NONSGML v1.0//EN CALSCALE:GREGORIAN METHOD:PUBLISH X-ORIGINAL-URL:https://www.scilifelab.se X-WR-CALDESC:Events for SciLifeLab REFRESH-INTERVAL;VALUE=DURATION:PT1H X-Robots-Tag:noindex X-PUBLISHED-TTL:PT1H BEGIN:VTIMEZONE TZID:Europe/Stockholm BEGIN:DAYLIGHT TZOFFSETFROM:+0100 TZOFFSETTO:+0200 TZNAME:CEST DTSTART:20240331T010000 END:DAYLIGHT BEGIN:STANDARD TZOFFSETFROM:+0200 TZOFFSETTO:+0100 TZNAME:CET DTSTART:20241027T010000 END:STANDARD BEGIN:DAYLIGHT TZOFFSETFROM:+0100 TZOFFSETTO:+0200 TZNAME:CEST DTSTART:20250330T010000 END:DAYLIGHT BEGIN:STANDARD TZOFFSETFROM:+0200 TZOFFSETTO:+0100 TZNAME:CET DTSTART:20251026T010000 END:STANDARD BEGIN:DAYLIGHT TZOFFSETFROM:+0100 TZOFFSETTO:+0200 TZNAME:CEST DTSTART:20260329T010000 END:DAYLIGHT BEGIN:STANDARD TZOFFSETFROM:+0200 TZOFFSETTO:+0100 TZNAME:CET DTSTART:20261025T010000 END:STANDARD END:VTIMEZONE BEGIN:VEVENT DTSTART;TZID=Europe/Stockholm:20250408T140000 DTEND;TZID=Europe/Stockholm:20250408T160000 DTSTAMP:20260404T104059 CREATED:20250317T085043Z LAST-MODIFIED:20250318T154905Z UID:10001508-1744120800-1744128000@www.scilifelab.se SUMMARY:Innovation Through Collaboration DESCRIPTION:Innovation Through Collaboration:AstraZeneca Open Innovation & Collaborative Insights from Malin Wickström & Arne Östman from Karolinska InstitutetBjörn Tyberg\, PhD and PIpresents AstraZeneca Open Innovation \n\n\n\nTOPICS TO BE COVERED \n\n\n\n\nCoSolve challenges\n\n\n\nPreclinical compound sharing\n\n\n\nCompound screening collaborations: Diversity screens\, Phenotypic screens\, Bespoke library screens and Secretome & other libraries\n\n\n\n\nTime will be given afterwards for 1:1 project discussions with interested investigators. To book a time slot\, please contact per.moberg@ki.se \n\n\n\nWe will meet up with individuals who do not have access to SciLifeLab at the reception at 13:55 \n\n\n\nTo book a time slot\, please contact per.moberg@ki.se URL:https://www.scilifelab.se/event/innovation-through-collaboration/ LOCATION:Gamma 2 Lunchroom\, SciLifeLab\, Tomtebodavägen 23\, Solna\, Sweden CATEGORIES:Event END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Stockholm:20250410T090000 DTEND;TZID=Europe/Stockholm:20250411T170000 DTSTAMP:20260404T104059 CREATED:20241119T120851Z LAST-MODIFIED:20250407T185455Z UID:10001406-1744275600-1744390800@www.scilifelab.se SUMMARY:Clinical Genomics 10th Anniversary Symposium – Genomic technologies transforming precision diagnostics DESCRIPTION:Celebrate a Decade of Innovation in Clinical Genomics!\n\n\n\nWe’re thrilled to invite you to the 10th Anniversary Symposium of the SciLifeLab Clinical Genomics Platform. This milestone event\, themed “Genomic Technologies Transforming Precision Diagnostics\,” will be held April 10–11\, 2025\, at the Conference Centre Wallenberg in Gothenburg\, Sweden. \n\n\n\nThis symposium marks ten years of progress in personalized medicine and genomic research. It will gather leading experts to explore groundbreaking advancements and discuss the future of clinical genomics\, oncology\, and precision diagnostics. \n\n\n\nThis event offers an excellent chance to engage with thought leaders\, exchange ideas\, and gain insights into the innovations shaping the future of medicine. Save the dates and join us in Gothenburg this April to celebrate a decade of progress and discovery! \n\n\n\nKey Topics\n\n\n\n\nCurrent and Emerging Next-Generation Sequencing Technologies\n\n\n\nTranslational Single Cell and Spatial Omics\n\n\n\nGenomics for Pathogen Detection and Pandemic Preparedness\n\n\n\nDiagnostic Analytics and Informatics\n\n\n\nThe Future of Genome-Based Diagnostics and Medicine\n\n\n\n\nThe event will also feature exhibitions and presentations by leading companies in genomic technologies\, showcasing their innovations and expertise. \n\n\n\nProgram\n\n\n\nCG_10years_ProgramDownload\n\n\n\nConference booklet\n\n\n\nCG10Y_ConferenceBooklet_digitalDownload\n\n\n\nConfirmed speakers\n\n\n\nView speakers\n\n\nAnnika Jenmalm Jensen\n\n\n\n\n\nInfrastructure Director at SciLifeLab and researcher at Karolinska Institutet. \n\n\n\n\n\n\n\n\n\n\n\n\n\nHelene Cederroth\n\n\n\n\n\nCo-founder and president of the Wilhelm Foundation. Board member of the Undiagnosed Diseases Network International \n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\nValtteri Wirta\n\n\n\n\n\nPlatform Scientific Director at Clinical Genomics Stockholm. Head of Office\, Department of Microbiology\, Tumor and Cell Biology\, Karolinska Institutet. \n\n\n\n\n\n\n\n\n\n\n\n\n\nLars Feuk\n\n\n\n\n\nCo-Director of the SciLifeLab National Genomics Infrastructure and Professor at Uppsala University. \n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\nLars Engstrand\n\n\n\n\n\nProfessor and senior physician at Karolinska Institutet\, directs the Centre for Translational Microbiome Research. \n\n\n\n\n\n\n\n\n\n\n\n\n\nRichard Rosenquist Brandell\n\n\n\n\n\nProfessor of Clinical Genetics at Karolinska Institutet and Senior Physician at Karolinska University Hospital\, Director of Genomic Medicine Sweden. \n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\nJoakim Lundeberg\n\n\n\n\n\nProfessor of molecular biotechnology at KTH Royal Institute of Technology\, renowned for developing Spatial Transcriptomics. \n\n\n\n\n\n\n\n\n\n\n\n\n\nOlli Dufva\n\n\n\n\n\nPhysician-scientist and postdoctoral fellow at the Wellcome Sanger Institute\, with expertise in computational analysis and functional genomics. \n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\nMikael Benson\n\n\n\n\n\nPrincipal researcher at Karolinska Institutet\, leading the Medical Digital Twin Research Group. \n\n\n\n\n\n\n\n\n\n\n\n\n\nMatt Brown\n\n\n\n\n\nProfessor at King’s College London and Chief Scientific Officer at Genomics England \n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\nAnders Ståhlberg\n\n\n\n\n\nProfessor in Clinical Genomics at the University of Gothenburg. Principal investigator at the Sahlgrenska Center for Cancer Research and the Wallenberg Centre for Molecular and Translational Medicine. \n\n\n\n\n\n\n\n\n\n\n\n\n\nTatjana Pandzic\n\n\n\n\n\nClinical laboratory geneticist and researcher at Uppsala University Hospital. Co-leads the hematology work package at Clinical Genomics Uppsala. \n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\nRene Kaden\n\n\n\n\n\nAssociate Professor at Uppsala University’s Department of Medical Sciences\, specializing in Clinical Microbiology. \n\n\n\n\n\n\n\n\n\n\n\n\n\nSofia Brunet\n\n\n\n\n\nPhD student at Sahlgrenska University Hospital\, with a background in clinical microbiology. \n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\nGöran Jönsson\n\n\n\n\n\nProfessor of molecular oncology at Lund University\, specializing in melanoma research. \n\n\n\n\n\n\n\n\n\n\n\n\n\nJessica Nordlund\n\n\n\n\n\nResearcher at Uppsala University’s Department of Medical Sciences\, where she leads the Molecular Precision Medicine research group. \n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\nAraz Rawshani\n\n\n\n\n\nAssociate professor at the University of Gothenburg’s Institute of Medicine and a resident physician in cardiology at Sahlgrenska University Hospital. \n\n\n\n\n\n\n\n\n\n\n\n\n\nMarcin Kierzcak\n\n\n\n\n\nBioinformatics data scientist at the National Bioinformatics Infrastructure Sweden (NBIS) and associate professor in bioinformatics at Uppsala University. \n\n\n\n\n\n\n\n\n\n\n\n\n\n\nConfirmed exhibitors\n\n\n\nView confirmed exhibitors\nGold Exhibitors\n\n\n\n\nillumina\n\n\n\nIntegrated DNA Technologies\n\n\n\nOxford Nanopore Technologies\n\n\n\nRoche Diagnostics Scandinavia\n\n\n\n\nSilver Exhibitors\n\n\n\n\nParse BioSciences\n\n\n\nTechtum Lab\n\n\n\nTriolab\n\n\n\n\nBronze Exhibitors\n\n\n\n\n10x Genomics\n\n\n\nBioNordika and their supplier New England Biolabs\n\n\n\nBruker Spatial Biology\n\n\n\nHamilton Nordic AB\n\n\n\nNordic Biolabs AB and their supplier Promega\n\n\n\nProteintech Europe\n\n\n\nSaveen & Werner\n\n\n\nTakara Bio\n\n\n\nThermo Fisher Scientific\n\n\n\n\n\nOrganizing committee\n\n\n\nView organizing committee\nThoas Fioretos\, Platform Director\, Clinical Genomics (until Dec 31\, 2024); Lund University \n\n\n\nLucia Cavelier\, Platform Co-Director\, Clinical Genomics (until Dec 31\, 2024); Uppsala University \n\n\n\nColum Walsh\, Platform Director\, Clinical Genomics (from Jan 1\, 2025);  Linköping University \n\n\n\nMalin Melin\, Platform Co-Director\, Clinical Genomics (from Jan 1\, 2025); Uppsala University \n\n\n\nMarcela Davila\, Platform Coordination Officer\, Clinical Genomics; University of Gothenburg \n\n\n\nEva Berglund\, Platform Strategy and External Relations Officer\, Clinical Genomics; Uppsala University \n\n\n\nMaria Smedh\, Site Coordinator; University of Gothenburg \n\n\n\n\nAccommodation\n\n\n\nA block of rooms has been reserved for symposium attendees at Elite Park Avenue Hotel\nElite Park Avenue Hotel\, is a centrally located hotel on Gothenburg’s main boulevard\, Avenyn (Kungsportsavenyn)\, for the nights of April 9 and 10. \n\n\n\nIf you wish to stay at this hotel\, please email reservations.gbgpark@elite.se and use “CG10years” as the booking code. If you prefer to pay by invoice\, be sure to provide complete invoicing details\, including information for e-invoicing. The room rates follow the governmental agreements (Kammarkollegiet). \n\n\n\nThe reserved rooms will be available until the end of March (5 weeks before arrival). After that\, unbooked rooms will be gradually released\, with all remaining reservations canceled 1 week before arrival. \n\n\n\n\nGetting There\n\n\n\nThe easiest way to travel within Gothenburg is by tram\,\nand the most convenient way to pay is by using the Västtrafik ToGo app\, which also includes a travel planner. \n\n\n\nFrom the Elite Park Avenue Hotel\n\n\n\nTo reach the conference center from the hotel\, take tram no. 7 from Valand (Track B) to Medicinaregatan. During rush hours\, tram 7 departs every 6 minutes. You can download the timetable here. The total journey\, including walking\, takes approximately 20 minutes. \n\n\n\nFrom Gothenburg Central Station\n\n\n\nTo get from the central train station to the conference center\, take tram no. 1\, 2\, or 7 from Centralstationen (Track C) to Medicinaregatan. During rush hours\, trams run every 2–4 minutes. The total journey\, including walking\, takes approximately 20 minutes. \n\n\n\n\n\n\n\n\n\nRegistration\n\n\n\n\nRegistration deadline: March 31\, 2025 URL:https://www.scilifelab.se/event/clinical-genomics-10th-anniversary-symposium-genomic-technologies-transforming-precision-diagnostics/ LOCATION:Conference Centre Wallenberg\, Medicinaregatan 20A\, Gothenburg\, 413 90\, Sweden CATEGORIES:Event ATTACH;FMTTYPE=image/jpeg:https://www.scilifelab.se/wp-content/uploads/2024/12/about_Mision_vision_2-1024x373_crop.jpg ORGANIZER;CN="Clinical Genomics Platform":MAILTO:marcela.davila@gu.se END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Stockholm:20250410T120000 DTEND;TZID=Europe/Stockholm:20250410T130000 DTSTAMP:20260404T104059 CREATED:20250109T102417Z LAST-MODIFIED:20250401T075412Z UID:10001439-1744286400-1744290000@www.scilifelab.se SUMMARY:Campus Solna Seminar Series: Emil Johansson & Solveig Thiele DESCRIPTION:Welcome to join the Campus Solna Seminar Series – an initiative to promote the fantastic science ongoing at Campus Solna and hopefully forge more internal communication and collaboration between within Campus Solna. The format consists of two 20 min talks (One speaker from the Alpha-building and one from the Gamma-building respectively)\, with an additional 5 min of questions. Presentation of ongoing (unpublished) projects is strongly encouraged. \n\n\n\nThe seminars are held Thursdays 12:00-13:00. You can bring your lunch to the seminar. \n\n\n\nPhD students that are attending the Campus Solna Seminar lectures will have the opportunity to gain credits. For the syllabus and instructions on how to obtain these credits\, read this document. Please contact your own department at your host University to confirm.See here the full schedule for this semester. \n\n\n\nThis week:\n\n\n\n\n\n\nEmil Johansson\n\n\n\nFredrik Edfors – alpha 6 \n\n\n\nThe blood plasma proteome in cardiovascular diseases \n\n\n\n\n\nSolveig Thiele\n\n\n\nJonathan Martin – gamma 5 \n\n\n\nReaching higher throughput for chemical exposomics of human serum with phospholipid removal and LC-HRMS \n\n\n\n\n\n\nThis seminar series is organized by the PhD & Postdoc Council. For more information about the Council and other events check our page. URL:https://www.scilifelab.se/event/campus-solna-seminar-series-leo-dahl-solveig-thiele/ LOCATION:Milkyway SciLifeLab Solna\, Tomtebodavägen 23\, Solna CATEGORIES:Community ATTACH;FMTTYPE=image/jpeg:https://www.scilifelab.se/wp-content/uploads/2022/09/IMG_20221103_123412496_HDR2-scaled.jpg ORGANIZER;CN="SciLifeLab Solna PhD & Postdoc Council":MAILTO:phd-council@scilifelab.se END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Stockholm:20250410T120000 DTEND;TZID=Europe/Stockholm:20250410T130000 DTSTAMP:20260404T104059 CREATED:20250326T125539Z LAST-MODIFIED:20250326T125540Z UID:10001515-1744286400-1744290000@www.scilifelab.se SUMMARY:Innovation through collaboration DESCRIPTION:AstraZeneca Open Innovation and Collaborative Insights from Mikael Elofsson\, UMU \n\n\n\n\nSpeakers: Björn Tyrberg and Hannah Semple present Open Innovation\, AstraZeneca\, covering: \n\n\n\n– CoSolve challenges– Preclinical compound sharing– Compound screening collaborations:–> Diversity screens–> Phenotypic screens–> Bespoke library screens–> Secretome and other libraries \n\n\n\n\nThe presentation will be given in Galaxen (Sirius)\, found on the ground floor of the Universum building\, at Umeå University. Find your way to the venue: MazeMap link. \n\n\n\nTime will be given afterwards for 1:1 project discussions with interested investigators. \n\n\n\nRegister to come to the presentation and reserve your lunch\, as well as book a 1:1 project discussion by Tuesday\, 8 April at 10:00.  \n\n\n\nRead more and register here URL:https://www.scilifelab.se/event/innovation-through-collaboration-2/ LOCATION:Galaxen (Sirius)\, Universum\, Umeå\, Universitetstorget 4\, Umeå\, 90187\, Sweden CATEGORIES:Event ATTACH;FMTTYPE=image/jpeg:https://www.scilifelab.se/wp-content/uploads/2022/05/AdobeStock_108274229_DNA_WP.jpg ORGANIZER;CN="SciLifeLab Ume%C3%A5":MAILTO:umea@scilifelab.se END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Stockholm:20250410T140000 DTEND;TZID=Europe/Stockholm:20250410T143000 DTSTAMP:20260404T104059 CREATED:20250328T132737Z LAST-MODIFIED:20250328T133332Z UID:10001516-1744293600-1744295400@www.scilifelab.se SUMMARY:CSI Seminar: Navigating Rejection in Academia DESCRIPTION:Rejection is an unavoidable part of academic life – whether it’s a rejected manuscript\, an unsuccessful grant application\, or job market setbacks. But while rejection is common\, it can still feel deeply personal and discouraging. Why does rejection sting so much\, and how can we navigate the emotions and self-doubt that come with it? In this seminar\, we’ll explore how common rejection in academia is\, the psychological impact of academic rejection\, strategies for maintaining resilience\, and ways to reframe setbacks as opportunities for growth. \n\n\n\nWe will begin with a ~ 20 min talk\, held in Solna and over zoom. Then proceed with a reflection and discussion held on-site. We encourage other sites to form watch parties\, by listening in together to the talk and then hold their own discussion afterwards. Hopefully seeding many local chapters of CSI. \n\n\n\nTo help facilitate discussion and reflection\, consider the following starter questions: \n\n\n\nAwareness: where do we experience rejection in our lives already? \n\n\n\nAnalysis: how well do I currently interact with rejection? \n\n\n\nAlternative: how could we relate to rejection in academia\, for ourselves and others? \n\n\n\nAction: how will knowledge of rejection in academia change my decisions going forward? URL:https://www.scilifelab.se/event/csi-seminar-navigating-rejection-in-academia/ LOCATION:Gamma 2 Lunchroom\, SciLifeLab\, Tomtebodavägen 23\, Solna\, Sweden CATEGORIES:Event ORGANIZER;CN="Coaching in Science Initiative (CSI)":MAILTO:sami.saarenpaa@scilifelab.se END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Stockholm:20250414T133000 DTEND;TZID=Europe/Stockholm:20250416T170000 DTSTAMP:20260404T104059 CREATED:20241128T105115Z LAST-MODIFIED:20250131T134602Z UID:10001412-1744637400-1744822800@www.scilifelab.se SUMMARY:SciLifeLab Train the Trainer Course DESCRIPTION:This course offers guidance\, ideas and tips for designing training/teaching\, development and delivery on training activities\, all based on research-driven educational principles. This course will cover the following topics: \n\n\n\n\nLearning principles and how they apply to training and teaching\n\n\n\nDesign and plan session\, course\, materials\n\n\n\nTeaching techniques to enhance learner engagement and participation\n\n\n\nAssessment and feedback in training and teaching\n\n\n\nCreating and maintaining engagement\n\n\n\n\nThis course is directed towards anyone who is interested in becoming a trainer/instructor\, or improving your training skills. If you have questions like the following ones\, this course may be very helpful to you. \n\n\n\n\nHow learning works?\n\n\n\nHow do I use learning principles and theories to improve my teaching/training?\n\n\n\nHow do I make my teaching/training more engaging and effective?\n\n\n\nHow should I adjust my teaching/training to different types of learners?\n\n\n\nHow do I ensure learning progress?\n\n\n\nHow can I assess whether my students are actually understanding my lessons? Are they actually learning?\n\n\n\nWhat is the best balance between theory and practice?\n\n\n\nHow can I best assess whether learning is occurring and/or has occurred?\n\n\n\nWhat works in a classroom and what doesn’t?\n\n\n\n\nImportant dates and information\n\n\n\nApplication open: November 25\, 2024Application closes: February 28\, 2025Confirmation to accepted applicants: March 7\, 2025 \n\n\n\nThe course will run:April 14: 13:30-16:30April 15: 09:00-16.30April 16: 09:00-16.30 \n\n\n\nNote: The course is highly interactive and hence it is important that you\, as a participant\, actively contribute to all sessions and elements of the course. \n\n\n\nRegistration\n\n\n\nTo preview the course content\, you can take a look at the 2024 Train the Trainer (Online) Course website \n\n\n\nLearning Objectives and Learning Outcomes\n\n\n\nLearning Objectives \n\n\n\n\nTo get acquainted with Learning principles and how they apply to training\n\n\n\nTo be able to select and use training techniques that can help enhance learner engagement and participation\n\n\n\nTo learn how to use assessment and feedback in training\n\n\n\nTo learn about session\, course\, and materials design as well as strategies for making learning engaging\n\n\n\n\nLearning Outcomes \n\n\n\nBy the end of this course\, learners will be able to: \n\n\n\n\nName learning principles that a good teacher/instructor should have in mind\n\n\n\nDescribe at least three training techniques\, drawing on learning principles\n\n\n\nDesign a training session and a course\n\n\n\nDevelop assessment questionnaires\n\n\n\nEnumerate types of materials needed for each part of a training session or course\n\n\n\nDescribe strategies to promote engagement amongst learners\n\n\n\n\nTarget Audience\n\n\n\nThis course is directed towards anyone who is interested in becoming a trainer/instructor\, or improving your training skills. \n\n\n\nCourse fee:\n\n\n\nNone. The course includes lunches\, coffee/tea and snacks. \n\n\n\nDue to limited space the course can accommodate a maximum of 25 participants. If we receive more applications\, participants will be selected based on selection criteria: Priority will be given to applicants from SciLifeLab infrastructures\, institutes and organizations across the Nordic research community\, and to participants from Nordic ELIXIR nodes. URL:https://www.scilifelab.se/event/scilifelab-train-the-trainer-course-2025/ LOCATION:BMC – Biomedical Centre (Lund)\, Sölvegatan 19\, Lund\, 22362\, Sweden CATEGORIES:Course ORGANIZER;CN="Training Hub":MAILTO:traininghub@scilifelab.se END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Stockholm:20250416T103000 DTEND;TZID=Europe/Stockholm:20250416T113000 DTSTAMP:20260404T104059 CREATED:20250411T070207Z LAST-MODIFIED:20250411T070749Z UID:10001527-1744799400-1744803000@www.scilifelab.se SUMMARY:Bringing Cells to Life of the Computer: Whole-Cell Modeling from Minimal Bacteria to Human Cells DESCRIPTION:Speaker\n\n\n\nZane R Thornburg\, PhD \n\n\n\nChemical Imaging and Structures Laboratory  \n\n\n\nUniversity of Illinois Urbana-Champaign \n\n\n\nAbstract\n\n\n\nThe goal of whole-cell modeling is to computationally predict the temporal progression of cell states. To simulate minutes to hours of biological time\, we sacrifice atomic resolution and instead use coarse-grained hybrid simulations. In these models\, large structures like membranes are projected onto a 3D cubic lattice\, macromolecules like proteins are individual particles\, and small molecules like metabolites are tracked as dynamic concentrations. Our most complete model is the genetically minimal bacterium in which we successfully simulate an entire cell cycle from start to division in 3D including the entire metabolic network and expression of its 493 genes. Organisms of more practical interest are significantly more complicated\, and many challenges still need to be discovered and overcome to model them. I will present two ongoing efforts in the areas of cell metabolism and mRNA splicing. One of the greatest challenges in metabolic modelling is determining a set of kinetic parameters. We present a method to determine sets of thermodynamically realistic kinetic parameters for enzymatic reactions in whole-cell metabolic models. The fate of a eukaryotic cell depends on proper maturation of its pre-mRNA through splicing. Variations in splicing of pre-mRNA from a single gene (alternative splicing) result in multiple isoforms of mature mRNA\, each producing a different protein with distinct biological activities. We model the kinetics of splicing to predict the frequencies at which the isoforms occur and demonstrate the model’s capabilities and limitations using known splicing isoforms from the human genome. \n\n\n\nContact: Erik Lindahl (erik.lindahl@scilifelab.se) URL:https://www.scilifelab.se/event/bringing-cells-to-life-of-the-computer-whole-cell-modeling-from-minimal-bacteria-to-human-cells/ LOCATION:Air&Fire\, SciLifeLab Stockholm\, Tomtebodavägen 23A\, Solna\, Sweden CATEGORIES:Event END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Stockholm:20250417T120000 DTEND;TZID=Europe/Stockholm:20250417T130000 DTSTAMP:20260404T104059 CREATED:20250109T102528Z LAST-MODIFIED:20250413T200859Z UID:10001440-1744891200-1744894800@www.scilifelab.se SUMMARY:Campus Solna Seminar Series: Ernest Cheng-De Liu & David Unnersjö-Jess DESCRIPTION:Welcome to join the Campus Solna Seminar Series – an initiative to promote the fantastic science ongoing at Campus Solna and hopefully forge more internal communication and collaboration between within Campus Solna. The format consists of two 20 min talks (One speaker from the Alpha-building and one from the Gamma-building respectively)\, with an additional 5 min of questions. Presentation of ongoing (unpublished) projects is strongly encouraged. \n\n\n\nThe seminars are held Thursdays 12:00-13:00. You can bring your lunch to the seminar. \n\n\n\nPhD students that are attending the Campus Solna Seminar lectures will have the opportunity to gain credits. For the syllabus and instructions on how to obtain these credits\, read this document. Please contact your own department at your host University to confirm.See here the full schedule for this semester. \n\n\n\nThis week:\n\n\n\n\n\n\nErnest Cheng-De Liu\n\n\n\nKasper Karlsson – alpha 5 \n\n\n\nEnhancing Neuroblastoma Organoid Diversity with Single-Cell Transcriptomics Heterogeneity Measurement \n\n\n\n\n\nDavid Unnersjö-Jess\n\n\n\nHjalmar Brismar – gamma 3 \n\n\n\nNanoscale Imaging with Advanced Image Analysis for Patient Stratification\, Drug Development\, and Diagnostics \n\n\n\n\n\n\nThis seminar series is organized by the PhD & Postdoc Council. For more information about the Council and other events check our page. URL:https://www.scilifelab.se/event/campus-solna-seminar-series-ernest-cheng-de-liu-david-unnersjo-jess/ LOCATION:Air&Fire\, SciLifeLab Stockholm\, Tomtebodavägen 23A\, Solna\, Sweden CATEGORIES:Community ATTACH;FMTTYPE=image/jpeg:https://www.scilifelab.se/wp-content/uploads/2022/09/IMG_20221103_124630107_HDR-scaled.jpg ORGANIZER;CN="SciLifeLab Solna PhD & Postdoc Council":MAILTO:phd-council@scilifelab.se END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Stockholm:20250422T100000 DTEND;TZID=Europe/Stockholm:20250422T110000 DTSTAMP:20260404T104059 CREATED:20250325T095113Z LAST-MODIFIED:20251125T145403Z UID:10001514-1745316000-1745319600@www.scilifelab.se SUMMARY:“It just works with my software” – How to adopt the FAIR principles in life science research at any career stage DESCRIPTION:This seminar will explain why funders promote the FAIR principles and showcase how the principles are useful to you in projects and collaborations of any size. The FAIR principles are intended to support effective data sharing up to the degree that you can assert “It just works with my software”. But they apply equally well to the social aspects of data sharing and can serve as a guide to help you address the question “If I leave the lab today\, how can my colleagues understand\, find and use my data?”. \n\n\n\nWhat you’ll learn: \n\n\n\n\nUnderstand the FAIR principles (Findable\, Accessible\, Interoperable\, and Reusable) and their importance in research.\n\n\n\nDiscover how adopting these principles can improve data sharing\, collaboration\, and long-term research impact.\n\n\n\nLearn practical strategies to make your data FAIR—valuable and usable for years to come.\n\n\n\n\nWho should attend? \n\n\n\nResearchers and professionals at any career stage who aim to optimize their data management practices. \n\n\n\nWhy attend? \n\n\n\nThis seminar offers actionable insights to help you align with funder expectations\, enhance research reproducibility\, and maximize the value of your data. \n\n\n\nPresenters: Wolmar Nyberg Åkerström and Niclas Jareborg (NBIS\, SciLifeLab) \n\n\n\nLink to the recording on YouTube. \n\n\n\nLink to the presentation slides. \n\n\n\nMore info\nThis event is part of the SciLifeLab Data Management seminar series\, an event series by the SciLifeLab Data Centre and NBIS joint Data Management team. \n\n\n\nThe goal of the events in this seminar series is to provide interesting interactive seminars around topics related to Research Data Management and Open Science in general\, and to foster discussions around best practices. \n\n\n\nThe events are open to everyone working at or affiliated with a Swedish research institute or university. We welcome all researchers\, educational professionals\, staff\, RDM professionals\, and others with an interest in life sciences\, from all university levels. The events are informal and inclusive\, so feel welcome to join and participate in our interesting discussions! \n\n\n\nThe events will be recorded and published openly after the seminars on the SciLifeLab YouTube channel. \n\n\n\nLink to the recording on will follow after the presentation. \n\n\n\nLink to the presentation slides will follow after the presentation.More information about SciLifeLab Data Centre and NBIS joint Data Management seminar series: https://www.scilifelab.se/data/scilifelab-data-management-seminar-series/ \n\n\n\nFor more information or inquiries\, please contact: data-management@scilifelab.se URL:https://www.scilifelab.se/event/datamanagement-fair-principles/ LOCATION:Online event via Zoom CATEGORIES:Event ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2024/02/DC_seminar-series_background1-1.png ORGANIZER;CN="Open Science Seminar Series":MAILTO:data-management@scilifelab.se END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Stockholm:20250422T151500 DTEND;TZID=Europe/Stockholm:20250422T161500 DTSTAMP:20260404T104059 CREATED:20250409T070149Z LAST-MODIFIED:20250409T070826Z UID:10001525-1745334900-1745338500@www.scilifelab.se SUMMARY:[The Svedberg seminar]-The origins and functional evolution of amniote sex chromosomes DESCRIPTION:Henrik Kaessmann \n\n\n\nProfessor of Evolutionary Genomics at Heidelberg \, Germany \n\n\n\nBio\n\n\n\nDr. Henrik Kaessmann is Professor of Evolutionary Genomics at Heidelberg University. His research focuses on the molecular foundations of mammalian phenotypic evolution\, leveraging various comparative and functional genomics approaches. After earning his Ph.D. at the Max Planck Institute for Evolutionary Anthropology\, he conducted postdoctoral research at the University of Chicago as an EMBO Fellow. His interdisciplinary lab\, which he initially established in Lausanne (Switzerland)\, has pioneered large-scale studies of gene expression changes and their phenotypic implications across various biological dimensions\, including organs\, species\, developmental stages\, gene expression layers\, coding and noncoding gene types\, splicing isoforms\, and sexes. Prof. Kaessmann has published extensively in leading journals and has received numerous prestigious honors\, including three ERC grants\, EMBO membership\, the Friedrich Miescher Award\, and the Cloëtta Prize. Beyond his research\, he teaches and mentors at Heidelberg University and maintains active collaborations with clinical researchers and major scientific institutions worldwide.Collectively\, Henrik Kaessmann’s transformative work has profoundly advanced our understanding of the molecular foundations of mammalian phenotypic evolution and the driving forces of natural selection. The remarkable scope of his lab‘s major findings demonstrates how large-scale genomics approaches can yield fundamental biological insights and test key hypotheses. Notably\, his interdisciplinary research has had far-reaching impact beyond evolution and development\, as evidenced by extensive citations across diverse fields. His findings\, including the observation of functional divergence of many genes between humans and mice\, and unique gene expression (i.e.\, transcriptome\, epigenome\, translatome) datasets  spanning key organs and developmental stages in humans and various model and non-model species\, have become indispensable resources for biomedical research in general. To maximize their impact\, his team has created interactive public databases that ensure optimal usability for the scientific community. \n\n\n\n \n\n\n\nThe origins and functional evolution of amniote sex chromosomes\n\n\n\n In our lab\, we carry out large-scale studies of gene expression changes and their phenotypic implications across various biological dimensions (e.g.\, species\, organs\, developmental stages\, gene expression layers\, coding and noncoding gene types\, splicing isoforms\, and sexes). In this seminar\, I will focus on our endeavors to unravel the origins of the different amniote sex chromosome systems\, which emerged from ancestral sets of autosomes. We have\, for example\, unveiled the origins of the sex chromosomes of therian (i.e.\, placental and marsupial) and monotreme mammals\, and those of birds and lizards. We then scrutinized the evolutionary and functional consequences of sex chromosome differentiations (i.e.\, the degeneration of Y or W chromosomes in males or females\, respectively) and the associated selective forces. Overall\, our work has illuminated the evolution of the specific gene contents on the respective sex chromosomes\, the origins and consequences of male (meiotic) sex chromosome inactivation\, and the forces and mechanisms underlying the evolution of the various amniote dosage compensation mechanisms\, including the drivers underlying the emergence of the female X inactivation mechanism in therians. I will present published and unpublished highlights of our work \n\n\n\nHost: Leif Andersson leif.andersson@imbim.uu.se URL:https://www.scilifelab.se/event/the-svedberg-seminar-henrik-kaessmann/ LOCATION:BMC Room C8:301\, Husargatan 3\, Uppsala\, Sweden CATEGORIES:Event ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2022/02/Picture1-The-Svedberg.png ORGANIZER;CN="The Svedberg Seminar Series":MAILTO:thesvedberg@scilifelab.uu.se END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Stockholm:20250423T120000 DTEND;TZID=Europe/Stockholm:20250423T180000 DTSTAMP:20260404T104059 CREATED:20250318T091324Z LAST-MODIFIED:20250417T045505Z UID:10001490-1745409600-1745431200@www.scilifelab.se SUMMARY:KI-SciLifeLab symposium 2025 DESCRIPTION:Join us at the fourth annual KI-SciLifeLab symposium. This is a half-day event that aims to bring together members of the SciLifeLab community at KI and others interested in our work. The afternoon will feature a series of scientific talks\, followed by a poster session and an opportunity to mingle. \n\n\n\nConfirmed speakers\n\n\n\n\nAndreas Luttens\n\n\n\nJan Ellenberg\n\n\n\nWilliam Nyberg\n\n\n\nStefanos Stagkourakis\n\n\n\nMelis Anahtar\n\n\n\nKonstantinos Georgiadis\n\n\n\nMikael Altun\n\n\n\nBrinton Seashore-Ludlow\n\n\n\nKimmo Kartasalo\n\n\n\n\nRead more\n\n\n\nRegistration\n\n\n\nProgram\n11:30Registration and lunch12:30Greetings from KI managementMartin Bergö\, Vice President Karolinska Institutet12:45Artificial intelligence for prostate computational pathologyKimmo Kartasalo13:00Navigating vast chemical spaces for drug discoveryAndreas Luttens13:15Greetings from SciLifeLab managementJan Ellenberg\, Director SciLifeLab13:30In vivo CRISPR engineering to reprogram T cells13.45Title TBAStefanos Stagkourakis14:00Coffee break14.30Deep learning-enabled discovery of antibiotics for Neisseria gonorrhoeaeMelis Anahtar15:15Delineating tumor evolution dynamics in breast cancer by time-course single-cell copy number profilingKonstantinos Georgiadis15:30Title TBAMikael Altun15.50High content imaging in advanced models for functional precision medicineBrinton Seashore-Ludlow16:30Poster Session17:00Announcement of best poster price\n\n\n\n\nOrganisers\nKimmo Kartasalo kimmo.kartasalo@ki.se \n\n\n\nWilliam Nyberg william.nyberg@ki.se \n\n\n\nStefanos Argyrios Stagkourakis stefanos.stagkourakis@ki.se \n\n\n\nAnn-Charlotte Zingmark ann-charlott.zingmark@ki.se URL:https://www.scilifelab.se/event/ki-scilifelab-symposium-2025/ LOCATION:Andreas Vesalius Lecture Hall\, Karolinska Institutet\, Berzelius väg 3\, Solna\, 171 65\, Sweden CATEGORIES:Event ATTACH;FMTTYPE=image/jpeg:https://www.scilifelab.se/wp-content/uploads/2022/07/SciLifeLab-Stockholm-2022-scaled.jpg END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Stockholm:20250423T130000 DTEND;TZID=Europe/Stockholm:20250424T150000 DTSTAMP:20260404T104059 CREATED:20250203T142407Z LAST-MODIFIED:20250304T131831Z UID:10001469-1745413200-1745506800@www.scilifelab.se SUMMARY:Data Management in Life Science DESCRIPTION:Registration Now Open \n\n\n\n\nRegister here\n\n\n\n\nSciLifeLab Linköping together with SciLifeLab Data Centre and NBIS welcomes all life-science researchers (from master student to PI)\, data support\, tech staff and infrastructure experts in Linköping to join this event where we explore the available support for research data handling and discuss on good data management practices according to FAIR principles and Open Science. \n\n\n\nOn-site event \n\n\n\nPROGRAM \n\n\n\nAPRIL 23 \n\n\n\n13:00-14:00 Good Data Management Practices – available services and support\n\nHere you will learn how to handle your research data according to FAIR principles and Open Science. The SciLifeLab Data Center\, NBIS and several units at LiU is providing knowledge\, tools and support in all life science data areas. \n\n\nLinköping University and SciLifeLab\, has signed the CoARA agreement along with many other universities and academic organizations all over the world. FAIR is the abbreviation for Findable\, Accessible\, Interoperable and Reusable. \n\n\nThis Open Lecture is for everyone in academia and health care handling research data \n\n\n\n\n\nAPRIL 24 \n\n\n\n9:00-10:00 FAIR breakfast for Master students\, PhD-students and Postdocs\nHere\, young scientists join for breakfast and discussions on FAIR principles and how to handle research data. FAIR is the abbreviation for Findable\, Accessible\, Interoperable and Reusable. Knowledge in good research data handling from the very beginning of a project is not only required from many funders and journals for publication\, it will also be of good help for the researcher throughout the project and beyond. \n\n\n\n\n10:15-12:00 Workshop 1 – Data Management Plans\n\nBring your laptop and we will guide you through the Data Management Plan support program that will help you create your own plan. \n\n\n\n\n\n13:15-15:00 Workshop 2 – Working with Human Data\n\nHow can we meet the requirements of Open Data\, FAIR and share data when we only work with Sensitive Human Data? Is it possible? URL:https://www.scilifelab.se/event/data-management-in-life-science/ LOCATION:Campus US\, Digitalis\, House 511\, floor 11\, Linköping CATEGORIES:Event ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2021/03/data_life_cycle_9.png ORGANIZER;CN="SciLifeLab Link%C3%B6ping":MAILTO:linkoping@scilifelab.se END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Stockholm:20250424T083000 DTEND;TZID=Europe/Stockholm:20250424T153000 DTSTAMP:20260404T104059 CREATED:20250228T152430Z LAST-MODIFIED:20250331T060445Z UID:10001496-1745483400-1745508600@www.scilifelab.se SUMMARY:SciLifeLab & AAAS/Science Publishing Workshop for Junior Researchers DESCRIPTION:Are you a junior researcher looking to navigate the scientific publishing landscape with confidence? Want to know what makes a great manuscript and how to optimize your chances of getting published in high-impact journals? \n\n\n\nJoin us for this highly regarded and rewarding interactive workshop hosted by SciLifeLab in collaboration with AAAS/Science\, designed for early career researchers (PhD students and postdocs).  \n\n\n\n\n\n\n\nWorkshop Leaders\n\n\n\nValda Vinson (Executive Editor\, Science Magazine) and Sacha Vignieri (Deputy Editor\, Research\, Science Magazine) are traveling all the way from the USA to provide you with exclusive insider insights into the entire publishing process – from writing and structuring your paper to peer review and post-publication impact.  \n\n\n\nWorkshop Content\n\n\n\nView Curriculum\nMorning session (hybrid)\n\n\n\nThe publishing landscape  \n\n\n\n\nTowards reproducibility\n\n\n\nOpen access and preprints   \n\n\n\nAuthorship      \n\n\n\nPicking a journal\n\n\n\n\nPreparing your paper  \n\n\n\n\nPlanning ahead\n\n\n\nStructure your paper \n\n\n\nCover Letter     \n\n\n\nTitle/Abstract     \n\n\n\nData accessibility\n\n\n\n\nThe Publication Process  \n\n\n\n\nProcess at Science\n\n\n\nReview process     \n\n\n\nWriting a review  \n\n\n\nOptimizing Impact (author promotion)\n\n\n\n\nAfternoon session (on-site)\n\n\n\nThis session features an interactive paper tutorial\, where participants will engage in in-depth group analysis and discussion of selected preprints—both those nominated by participants and publications chosen by the Editors. \n\n\n\nPlease note: Pre-workshop preparation is required for all participants. \n\n\n\nThe selected preprints should fall under one of the following categories: \n\n\n\n\nCell and Molecular Biology\n\n\n\nGenomics\, Proteomics and Systems Biology Approaches  \n\n\n\nEcology and Environment  \n\n\n\nMolecular Medicine\n\n\n\n\n\nPractical Details\n\n\n\nThe workshop is divided into two sessions: \n\n\n\n🔹 Morning Session (Hybrid) – A Zoom link will be provided to online participants one day before the workshop.🔹 Afternoon Session (On-site) – Focused on preprints within life science topics (see Curriculum for details). \n\n\n\nParticipation Guidelines\n\n\n\n🔹 PhD students and postdocs in life sciences will be prioritized for the on-site session.🔹 Pre-workshop preparation is required for all on-site participants.🔹 Everyone is welcome to join online.🔹 On-site participation includes lunch and coffee breaks with the Science Editors. \n\n\n\nOn-site participation is limited to 40 spots!\n\n\n\nParticipants for the on-site workshop will be selected after the application deadline based on:✔️ Affiliation (to ensure a fair distribution across research groups).✔️ First come\, first served basis. \n\n\n\n📅 Deadline for onsite application: March 24\, 2025 \n\n\n\n📅 Deadline for online registration: April 22\, 2025 \n\n\n\n\nApply here URL:https://www.scilifelab.se/event/scilifelab-aaas-science-publishing-workshop-for-junior-researchers/ LOCATION:Birgit Thilander Lecture Hall\, Medicinaregatan 3\, Göteborg CATEGORIES:Event ATTACH;FMTTYPE=image/jpeg:https://www.scilifelab.se/wp-content/uploads/2025/02/IMG_2323-2048x1536-1.jpg ORGANIZER;CN="SciLifeLab Gothenburg":MAILTO:gothenburg@scilifelab.se END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Stockholm:20250424T120000 DTEND;TZID=Europe/Stockholm:20250424T130000 DTSTAMP:20260404T104059 CREATED:20250109T102640Z LAST-MODIFIED:20250413T200938Z UID:10001441-1745496000-1745499600@www.scilifelab.se SUMMARY:Campus Solna Seminar Series: Erik Wernersson & Stefan Wennmalm DESCRIPTION:Welcome to join the Campus Solna Seminar Series – an initiative to promote the fantastic science ongoing at Campus Solna and hopefully forge more internal communication and collaboration between within Campus Solna. The format consists of two 20 min talks (One speaker from the Alpha-building and one from the Gamma-building respectively)\, with an additional 5 min of questions. Presentation of ongoing (unpublished) projects is strongly encouraged. \n\n\n\nThe seminars are held Thursdays 12:00-13:00. You can bring your lunch to the seminar. \n\n\n\nPhD students that are attending the Campus Solna Seminar lectures will have the opportunity to gain credits. For the syllabus and instructions on how to obtain these credits\, read this document. Please contact your own department at your host University to confirm.See here the full schedule for this semester. \n\n\n\nThis week:\n\n\n\n\n\n\nErik Wernersson\n\n\n\nMagda Bienko – alpha 4 \n\n\n\nFISH probe design: Aligners and Anti-Aligners \n\n\n\n\n\nStefan Wennmalm\n\n\n\nHans Blom – gamma 3 \n\n\n\nMINFLUX tracking of single molecules in cells at the Advanced Light Microscopy Facility \n\n\n\n\n\n\nThis seminar series is organized by the PhD & Postdoc Council. For more information about the Council and other events check our page. URL:https://www.scilifelab.se/event/campus-solna-seminar-series-erik-wernersson-stefan-wennmalm/ LOCATION:Air&Fire\, SciLifeLab Stockholm\, Tomtebodavägen 23A\, Solna\, Sweden CATEGORIES:Community ATTACH;FMTTYPE=image/jpeg:https://www.scilifelab.se/wp-content/uploads/2022/12/IMG_4110-scaled.jpg ORGANIZER;CN="SciLifeLab Solna PhD & Postdoc Council":MAILTO:phd-council@scilifelab.se END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Stockholm:20250424T123000 DTEND;TZID=Europe/Stockholm:20250424T150000 DTSTAMP:20260404T104059 CREATED:20250411T134743Z LAST-MODIFIED:20250411T134911Z UID:10001530-1745497800-1745506800@www.scilifelab.se SUMMARY:EATRIS Sweden Spotlight Workshop DESCRIPTION:AI in Biomarker Research and Development – Sweden Spotlight Workshop \n\n\n\nJoin us for an engaging workshop as part of the Swedish Spotlight on AI in Healthcare. The EATRIS Biomarkers Platform is proud to participate in “AI in Biomarker Research and Development\,” an event dedicated to exploring the entire biomarker development value chain. Together\, we will tackle key challenges\, explore pivotal decision points\, and uncover innovative AI-driven solutions. \n\n\n\nMore Information and Registration\n\n\n\nAgenda\n\n\n\n12:30 – 12:40 | Welcome & Introduction \n\n\n\n\nModerator: Emanuela Oldoni (EATRIS)\, Pontus Aspenström (National Director\, Sweden)\n\n\n\nSciLife lab introduction (Annika Jensen\, Infrastructure Director SciLifeLab)\n\n\n\nOverview of workshop objectives and structure\n\n\n\n\n12:40 – 13:10 | Keynote lecture: Unlocking the Future: AI-Driven Innovation in Biomarker Research and Healthcare \n\n\n\n13:10– 14:00 | Expert Presentations on AI & Biomarker Development \n\n\n\n\nUse of computational tools on Biomarker discovery Speaker: Yike Xie\, Gothenburg University\n\nRNA-based liquid biopsy and single-cell genomics in the context of human disease\n\n\n\n\n\nChallenges in Leveraging AI for Digital Biomarkers in Healthcare Speaker: Tim van den Broek\, TNO\n\nDefinition of digital biomarkers\n\n\n\nAddressing key challenges in data quality\, standardization\, and integration\n\n\n\nStrategies to enhance reproducibility and regulatory acceptance of AI-driven digital biomarkers\n\n\n\n\n\nAI-Biomarkers Validation & Qualification Speaker: [Nina Linder\, Helsinki/Uppsala University]\n\nChallenges in translating AI-derived biomarkers into validated clinical applications\n\n\n\n\n\n\n14:00 – 14:45 | Roundtable Discussion: Overcoming Challenges & Unlocking Opportunities \n\n\n\n\nModerated by Emanuela Oldoni\, Platform manager for the EATRIS Biomarkers Platform\n\n\n\nPanelists: [speakers+Biomarkers chairs]\n\n\n\nKey topics:\n\nGaps in AI-driven biomarker development\n\n\n\nStrategies for data integration & standardization\n\n\n\nRegulatory considerations & validation hurdles\n\n\n\nCollaboration models for AI implementation in biomarker R&D\n\n\n\n\n\n\n14:45 – 15:00 | Closing Remarks & Next Steps (Emanuela\, Ulrika) \n\n\n\n\nSummary of key takeaways\n\n\n\nPotential follow-up actions and collaboration URL:https://www.scilifelab.se/event/eatris-sweden-spotlight-workshop/ CATEGORIES:Event END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Stockholm:20250424T153000 DTEND;TZID=Europe/Stockholm:20250424T170000 DTSTAMP:20260404T104059 CREATED:20250414T071625Z LAST-MODIFIED:20250416T112350Z UID:10001531-1745508600-1745514000@www.scilifelab.se SUMMARY:BAM Seminar: Transitioning from Academia to Start-up & Entrepreneurship DESCRIPTION:As part of our “Biology At Most” seminar series we invite speakers from all types of life science career paths. They will share their visions\, perspectives and expertise in their field in a informal environment. \n\n\n\nToday’s guests are SciLifeLab and/or academia alumni with start-up experience\n\n\n\nOur speakers will discuss the transition from academia to start-ups\, share experience\, and have a panel-discussion with questions from people from the SciLifeLab community. \n\n\n\nWe will have time for fika at the seminar and the pub will be open for networking & mingle after. Please register via the google form until April 20th to be considered for the fika. \n\n\n\nSpeakers:\n\n\n\nJudy Mielke – ScientifyRESEARCH \n\n\n\nSimon Fredriksson – Pixelgen \n\n\n\nDavid Kotol – Proteome Edge \n\n\n\nBanushree Kumar – Epigenica \n\n\n\n\n\n\n\n\nProgram\n\n\n\n\n\n15.30-15.35 \n\n\n\n\n\nWelcome \n\n\n\n\n\n\n\n15.35-15.55 \n\n\n\n\n\nPanelists introductions \n\n\n\n\n\n\n\n15.55-16.35 \n\n\n\n\n\nPanel discussion – Public discussion with all panel members \n\n\n\n\n\n\n\n16.35-16.55 \n\n\n\n\n\nBreakout sessions – Smaller group discussion with your favorite panel member \n\n\n\n\n\n\n\n16.55-17.00 \n\n\n\n\n\nClosing remarks (continue mingling at pub) \n\n\n\n\n\n\n\n\n\n\n\n\n\n\nThis seminar series is organized by the PhD & Postdoc Council. For more information about the Council and other events check our page. URL:https://www.scilifelab.se/event/bam-seminar-transitioning-from-academia-to-start-up-entrepreneurship/ LOCATION:Gamma 2 Lunchroom\, SciLifeLab\, Tomtebodavägen 23\, Solna\, Sweden CATEGORIES:Community ATTACH;FMTTYPE=image/jpeg:https://www.scilifelab.se/wp-content/uploads/2022/11/BAM.jpg ORGANIZER;CN="SciLifeLab Solna PhD & Postdoc Council":MAILTO:phd-council@scilifelab.se END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Stockholm:20250425T090000 DTEND;TZID=Europe/Stockholm:20250425T094000 DTSTAMP:20260404T104059 CREATED:20250408T075501Z LAST-MODIFIED:20250408T114952Z UID:10001524-1745571600-1745574000@www.scilifelab.se SUMMARY:Locoregional cancer therapies for uveal melanoma. DESCRIPTION:Speaker: Roger Olofsson Bagge\, Professor och Överläkare \n\n\n\nAvdelningen för Kirurgi\, Institutionen för kliniska vetenskaper\, Sahlgrenska Akademin\, Göteborgs Universitet\, Sektionen för Bröst och Melanomkirurgi\, Kirurgi\, Sahlgrenska Universitetssjukhuset \n\n\n\nAbstract \n\n\n\nUveal melanoma is a cancer arising from the eye. Prognosis is poor in that patients often develop liver metastases and no effective treatments are currently available. Our recent phase III randomized trial (SCANDIUM) demonstrated the effectiveness of locoregional treatment with isolated hepatic perfusion (IHP) while our translational research suggests that this treatment can activate the immune system. By sensitizing uveal melanoma to immunotherapy\, efficacy of treatment may be further increased as we showed by combining IHP with modern immunotherapy (SCANDIUM-II). \n\n\n\nThe purpose of this randomized clinical trial\, the SCANDIUM-III trial\, is to further explore treatment efficacy with a novel clinical trial combining a locoregional cancer treatment with modern immunotherapy. The specific aim is to evaluate if the combination of minimal-invasive percutaneous hepatic perfusion together with the checkpoint inhibitors ipilimumab and nivolumab can improve response rate and survival. Patients will be included from all regions of Sweden\, and if achieving clinically significant findings from the trial the procedure will likely be incorporated into clinical practice without major delays. \n\n\n\nA major limitation is that we currently lack predictive and prognostic factors. We therefore aim to perform a multimodal precision medicine approach using ctDNA\, proteomics\, metabolomics as well as immuneprofiling in both existing samples (SCANDIUM and SCANDIUM-II) as well as prospectively in the SCANDIUM-III trial\, aiming at correlating multimodal liquid biopsies with tumor response\, progression and survival. \n\n\n\nPatients\, clinical samples\, infrastructure and other resources needed for the project are available through the participating University hospital sites and Comprehensive Cancer Center structures. We use the research infrastructure Clinical Studies Sweden – Gothia Forum for clinical trial support\, Biobank Sweden for biobanking and SciLifeLab for our planned multimodal analysis. \n\n\n\nregistration\n\n\n\nAbout Clinical Talks \n\n\n\nAfter seven successful seasons and over seventy dedicated speakers\, we are excited to continue showcasing the contributions of our diverse clinical\, academic\, and industry Life Science community. This season will feature ten insightful talks following our well-established format. \n\n\n\nThe overarching theme is “How to Achieve Feasible Implementation.” Sessions will be held monthly on Fridays from 09:00 to 09:30 a.m. via Zoom\, with occasional exceptions. Each talk will be followed by an engaging Q&A session\, moderated by standing host Rikard Fred and a guest moderator with subject matter expertise to enrich the discussion. \n\n\n\nIn today’s rapidly evolving post-pandemic landscape\, exploring how academic\, clinical\, and industry research—combined with technological advancements—can drive practical and sustainable solutions is crucial. Join us for an opportunity to gain fresh insights\, expand your knowledge\, and connect with experts shaping the future of Life Sciences! URL:https://www.scilifelab.se/event/locoregional-cancer-therapies-for-uveal-melanoma/ LOCATION:Online event via Zoom CATEGORIES:Event ORGANIZER;CN="Clinical Talks":MAILTO:precisionmedicine@scilifelab.se END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Stockholm:20250425T100000 DTEND;TZID=Europe/Stockholm:20250425T110000 DTSTAMP:20260404T104059 CREATED:20250403T100003Z LAST-MODIFIED:20250403T100224Z UID:10001522-1745575200-1745578800@www.scilifelab.se SUMMARY:Towards an interpretable deep learning model of cancer cells. DESCRIPTION:Avlant Nilsson\, DDLS fellow\, Karolinska Institutet \n\n\n\nNBIS and SciLifeLab Data Centre arrange an open SciLifeLab AI Seminar Series aimed at knowledge-sharing about Artificial Intelligence and applications in the Life Science community. The seminar series is open to everyone. The seminar is run over Zoom on the third Friday of the month during academic terms\, typically between 10 and 11 am\, with approx. 45 min presentation and 15 min discussion. \n\n\n\nAbstract \n\n\n\nCancer emerges from complex molecular interactions that drive pathological cells states. To model these interactions\, we develop deep learning frameworks of cellular signaling\, gene regulation\, and metabolism. Our approach embeds prior knowledge networks into a recurrent architecture\, allowing us to capture cellular dynamics by training on omics data across different perturbations and conditions.At the core of our modeling is a propagator function that predicts the next cell state based on the current state\, enabling the simulation of molecular state transitions over time. To ensure biological plausibility\, we employ a technic based on feature embedding and superposition that encodes molecular identities in a structured feature space while restricting the predictive input for each molecular state to its direct network connections. These structured embeddings facilitate the use of a universal function allowing generalization across different molecules\, cell types\, and experimental settings.By constraining learned representations to known molecular entities\, our framework maintains interpretability while enabling data-driven inference. Ultimately\, we aim to integrate our models into a unified representation of cellular behavior. Bridging mechanistic understanding with predictive modeling\, this work lays the foundation for AI-driven precision medicine\, offering new tools to simulate and control cancer cell states. URL:https://www.scilifelab.se/event/towards-an-interpretable-deep-learning-model-of-cancer-cells/ LOCATION:Online event via Zoom CATEGORIES:Event END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Stockholm:20250428T100000 DTEND;TZID=Europe/Stockholm:20250428T113000 DTSTAMP:20260404T104059 CREATED:20250424T080857Z LAST-MODIFIED:20250424T081131Z UID:10001535-1745834400-1745839800@www.scilifelab.se SUMMARY:Translational Control of Membrane Excitability DESCRIPTION:Research seminar by Gail Robertson\, PhD \n\n\n\nKellett Professor & Director\, Training Program in Translational Cardiovascular Science\, University of Wisconsin-Madison \n\n\n\nFlier_250428_RobertsonDownload\n\n\n\nAs part of professor Robertson’s visit\, the Campus Solna DEI committee is arranging an afternoon session in the Gamma 7 lunch room to discuss differents perspectives and research and conduct in life science. \n\n\n\nFlier_250428 Robertson DEISDownload\n\n\n\nContact: Reba Howard (rebecca.howard@scilifelab.se)  URL:https://www.scilifelab.se/event/translational-control-of-membrane-excitability/ LOCATION:Air&Fire\, SciLifeLab Stockholm\, Tomtebodavägen 23A\, Solna\, Sweden CATEGORIES:Event ATTACH;FMTTYPE=image/jpeg:https://www.scilifelab.se/wp-content/uploads/2024/03/DEISlogo.jpg ORGANIZER;CN="Molecular Biophysics Stockholm":MAILTO:join-mbp@scilifelab.se. END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Stockholm:20250429T120000 DTEND;TZID=Europe/Stockholm:20250429T130000 DTSTAMP:20260404T104059 CREATED:20250411T124253Z LAST-MODIFIED:20250411T124255Z UID:10001528-1745928000-1745931600@www.scilifelab.se SUMMARY:Umeå seminar series: Discover your sample in 3D using volume EM by FIB-SEM DESCRIPTION:Presenter: Sara Henriksson\, Staff scientist\, Umeå Centre for Electron Microscopy (UCEM)\, Umeå University \n\n\n\nAbstract: FIB-SEM is a conventional scanning electron microscope equipped with a focused ion beam. This beam is destructive which enables shaping of objects inside of the microscope. Such a microscope can act as a knife\, removing section by section of a sample. Together with high-quality sample preparation and electron detectors\, this facilitates a volumetric view of any given sample at high magnification and resolution. This seminar will describe the method in more detail and give examples of supported projects and applications. \n\n\n\n\nREGISTRATION\n\n\n\nSign up for the IRL seminar on the 29th of April and reserve your free lunch (salad\, drink\, and a little sweet snack) by Friday\, 25th April\, 13:30 in the form below\, or follow online here: https://www.umu.se/en/research/groups/scilifelab/scilifelab-site-umea–kbc-infrastructure-seminar-series/ URL:https://www.scilifelab.se/event/umea-seminar-series-discover-your-sample-in-3d-using-volume-em-by-fib-sem/ LOCATION:Glasburen Seminar Room\, Chemical Biological Centre (KBC) Building\, Umeå University\, Umeå\, 901 87\, Sweden CATEGORIES:Event ATTACH;FMTTYPE=image/webp:https://www.scilifelab.se/wp-content/uploads/2025/04/chlamydia_infected_cell_fib-sem-Sara-Henriksson.webp ORGANIZER;CN="SciLifeLab Ume%C3%A5":MAILTO:umea@scilifelab.se END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Stockholm:20250429T150000 DTEND;TZID=Europe/Stockholm:20250429T160000 DTSTAMP:20260404T104059 CREATED:20250409T152618Z LAST-MODIFIED:20250409T152810Z UID:10001526-1745938800-1745942400@www.scilifelab.se SUMMARY:Unlocking Innovation: Best Practices for Corporate-Academic Partnerships DESCRIPTION:SwedenBIO’s IP Task force is inviting you to an engaging seminar on how to level up your academic collaborations. We will present our Term Sheet Checklist\, a tool designed to simplify and secure successful agreements between industry and academia in the Life Science sector. You’ll also get an exclusive look at the Data Driven Life Science (DDLS) program\, showcasing their unique training and research opportunities for industry PhD students. \n\n\n\nKey Topics: \n\n\n\nIntroduction of the Data Driven Life Science program (DDLS) \n\n\n\nUnlocking Innovation and collaboration \n\n\n\nLaunch of Term Sheet Checklist \n\n\n\nVenue\n\n\n\nStockholmCirio Advokatbyrå AB\, Biblioteksgatan 9View mapGothenburgGoCo Health Innovation City\, Entreprenörsstråket 10View mapJoin OnlineYou will get an invitation when the event is close \n\n\n\nRead more and Register here URL:https://www.scilifelab.se/event/unlocking-innovation/ CATEGORIES:Event END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Stockholm:20250429T151500 DTEND;TZID=Europe/Stockholm:20250429T161500 DTSTAMP:20260404T104059 CREATED:20250403T050210Z LAST-MODIFIED:20250428T110224Z UID:10001517-1745939700-1745943300@www.scilifelab.se SUMMARY:[Spotlight seminar] Using comparative functional genomics to map genetic networks DESCRIPTION:ScilifeLab Spotlight seminar series proudly welcomes Brenda J. Andrews\, Ph.D.\, C.C.\, FRSC\, University of Toronto \n\n\n\n\n\n\n\nBiography\n\n\n\nProfessor Brenda Andrews earned her PhD at the University of Toronto and completed a postdoctoral fellowship with legendary yeast researcher Ira Herskowitz at the University of California San Francisco. She returned to Toronto\, establishing her independent lab in the Department of Molecular Genetics (previously Medical Genetics) and later chairing the department (1999–2004). In 2004\, she was appointed the inaugural director of the Donnelly Centre\, leading it for 15 years. \n\n\n\nUnder her leadership\, the Donnelly Centre became a hub for large-scale genomics and proteomics\, known for state-of-the-art labs and robotics. She fostered a creative collaborative\, interdisciplinary environment\, integrating computer science\, bioinformatics\, chemistry\, engineering\, and biology to tackle fundamental biological questions and inventing technologies to answer them. The Centre’s discoveries\, frequently featured in top journals\, have transformed our understanding of cellular machinery and disease mechanisms. Notedly\, the Donnelly Centre is also known for its productive public outreach efforts\, hosting educational events aimed at instilling curiosity and love of science in the young\, especially girls. \n\n\n\nProfessor Andrews launched the Accelerator for Donnelly Collaboration\, a biotechnology incubator for start-ups and companies to partner with the Centre’s investigators\, with the aim to exploit results obtained in the basic science into medical advances. She is the founding editor-in-chief of the journal G3 Genes|Genomes|Genetics\, an open access journal of the Genetics Society of America. She is also as a member on the Governing Council of the Canadian Institutes for Health Research\, the primary federal funding agency for medical research\, and she served as the inaugural director of the Genetic Networks program at the Canadian Institute for Advanced Research. \n\n\n\nA pioneer in large-scale genetics and cell biology\, Professor Andrews has authored over 200 publications and received numerous national and international honors\, including being named a Companion of the Order of Canada\, the highest national honor that can be bestowed on any Canadian citizen. She is the Canada Research Chair in Systems Genetics & Cell Biology\, a Fellow of the Royal Society of Canada\, and an international member of the U.S. National Academy of Sciences. \n\n\n\nAs can be appreciated from this brief introduction\, SciLifeLab Campus Solna shares many of the ambitions and values Professor Andrews has championed at the Donnelly Centre. We are honored to host her for a seminar in the Spotlight Series on April 29 at 15:15 in the lecture room Air&Fire. She will present the latest news regarding her genetic network projects in a seminar entitled “Using Comparative Functional Genomics to Map Genetic Networks.” \n\n\n\nPlease contact (per.ljungdahl@scilifelab.se) if you would like to speak with Professor Andrews. \n\n\n\nMeet the speaker\n\n\n\nAfter the seminar\, the PhD council arranges a Meet the Speaker session\, please register here if you want to take part. URL:https://www.scilifelab.se/event/using-comparative-functional-genomics-to-map-genetic-networks/ LOCATION:Air&Fire\, SciLifeLab Stockholm\, Tomtebodavägen 23A\, Solna\, Sweden CATEGORIES:Event ATTACH;FMTTYPE=image/jpeg:https://www.scilifelab.se/wp-content/uploads/2023/10/Campus-solna-seminar-picture.jpg ORGANIZER;CN="Spotlight Seminar Series":MAILTO:events@scilifelab.se END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Stockholm:20250505T120000 DTEND;TZID=Europe/Stockholm:20250506T130000 DTSTAMP:20260404T104059 CREATED:20241220T130709Z LAST-MODIFIED:20250504T184509Z UID:10001423-1746446400-1746536400@www.scilifelab.se SUMMARY:Infectious disease epidemiology: surveillance\, forecasting and modelling DESCRIPTION:Join the Data-driven Epidemiology and Biology of Infection research area for an inspiring Lunch-to-lunch meeting filled with science\, networking\, and discussions. \n\n\n\nThis event is arranged by the Data-driven Life Science program (DDLS)\, hosted by SciLifeLab and Knut and Alice Wallenberg Foundation. \n\n\n\nThe DDLS research area symposia series aims to engage and build a strong national scientific community around the DDLS research themes. Each of the four areas arranges two symposia per year. Everyone interested in data-driven research is welcome to take part. We want to bring together researchers\, industry\, and healthcare to foster collaboration and push the frontiers of data-driven life science. \n\n\n\nDate: May 5 – 6\, 2025 \n\n\n\nTime: Lunch to Lunch \n\n\n\nVenue: PÄRLAN – Albano – Hus 1 / Plan 6\, See map. \n\n\n\n \n\n\n\nRegistration\n\n\n\nThe event has reached full capacity. \n\n\n\n\n\n\n\nProgram\n\n\n\nDDLS EBI program_May 2025_v3Download\n\n\n\nPractical information\n\n\n\nDirections: Albano is between the main campus of Frescati and Roslagstull. You can either walk from T: Tekniska högskolan (exit Körsbärsvägen) or T: Universitet. By bus you can either take bus 50 from T-Odenplan (direction Universitetet) or from T-Universitetet (direction Odenplan) and get off at Albano. It is easiest to enter the buildings from the main road Roslagsvägen – then you are on level 2. \n\n\n\nStart: at 12:00 with Lunch or 13:00 in the Lecture hall on May 5. \n\n\n\nRegistration: We’ll begin with Registration (from 11:45) and Lunch\, 12:00-12:45 at Restaurant Proviant Albano located in House 2 on Level 4. You need to register with your name or QR code (sent by email on May 5) at the SciLifeLab table outside the Restaurant to get a lunch coupon and a name badge before eating lunch. The Lecture hall is a short walk from the lunch restaurant. \n\n\n\nPlease be seated in Pärlan at 13:00 to start the Symposium. If you do not attend lunch\, you can register and get your name badge in the Lecture room. \n\n\n\nLecture hall: Pärlan. Located on floor 6 in House 1. \n\n\n\nImportant: The room is only accessible by elevator. Be sure to find the correct elevator\, which is located deep inside the building\, heading towards House 2. The code to the door and the elevator will be written on your name badge and communicated in the Welcome emails. \n\n\n\n \n\n\n\nmap_albanoDownload\n\n\n\nOrganizing committee:\n\n\n\n\nTom Britton\, Stockholm University\n\n\n\nStefan Engblom\, Uppsala University\n\n\n\nLaura Carroll\, Umeå University\n\n\n\nTove Fall\, Uppsala University\n\n\n\n\nQuestions can be answered by the Organizing Committee or events@scilifelab.se \n\n\n\nRead more about the Research area URL:https://www.scilifelab.se/event/ddls-ebi-symposium/ LOCATION:PÄRLAN – Albano – Hus 1 / Plan 6\, Roslagsvägen 26\, Stockholm\, 114 19 CATEGORIES:Event ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2023/03/EBI_web.png END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Stockholm:20250505T130000 DTEND;TZID=Europe/Stockholm:20250509T123000 DTSTAMP:20260404T104059 CREATED:20241128T102310Z LAST-MODIFIED:20250113T123652Z UID:10001411-1746450000-1746793800@www.scilifelab.se SUMMARY:Open Science in the Swedish Context DESCRIPTION:Are you ready to meet Sweden’s Open Science goals? \n\n\n\nIn this multifaceted\, interactive\, national course\, a panel of experts from across Sweden’s Open Science landscape will equip participants with the most important tools needed to implement Open Science practices into every step of the research project lifecycle.  \n\n\n\nTopics covered include: \n\n\n\n\nOpen Science: what’s in it for you?\n\n\n\nThe state of Open Science in Sweden\n\n\n\nEliminating publication bias: how to publish a registered report\n\n\n\nData reuse with the help of data repositories\n\n\n\nGood research practice in Sweden\n\n\n\nNew ways of academic publishing: Open Access and beyond\n\n\n\nGetting credit for all your research outputs: DOIs and licensing\n\n\n\nAdvances in researcher evaluation: funder and institutional perspectives\n\n\n\nScience communication and citizen science\n\n\n\n\nThis is a nationally offered course open to PhD students\, postdocs\, researchers\, PIs and other employees at all Swedish universities who would want to implement Open Science practices into every step of their research projects.  \n\n\n\nImportant dates and information:\n\n\n\nApplication open: November 28\, 2024 \n\n\n\nApplication closes: February 28\, 2025 \n\n\n\nConfirmation to accepted applicants: March 7\, 2025 \n\n\n\nThis course runs in-person from May 5-9\, with an additional online session on May 27th! \n\n\n\nPlease note:  \n\n\n\n\nThis course is highly interactive and hence it is important that you\, as a participant\, actively contribute to all sessions and elements of the course. \n\n\n\nParticipants need to bring a laptop.\n\n\n\n\nRegistration\n\n\n\nCourse website\n\n\n\nCourse Fee:\n\n\n\nNone. The course includes lunches\, coffee/tea and snacks. \n\n\n\nLearning outcomes\n\n\n\nUpon completion of this course\, participants will be able to: \n\n\n\n\nExplain what Open Science is\, and discuss the benefits and challenges that come with its implementation\, specifically in the Swedish context\n\n\n\nDescribe the most common Open Science practices throughout every step of the research project lifecycle\n\n\n\nImplement Open Science practices into their own workflow\n\n\n\n\nThis course is led by\n\n\n\nIneke Luijten (SciLifeLab\, 0000-0001-5768-275X) ineke.luijten@scilifelab.se\,  \n\n\n\nElin Kronander (NBIS\, 0000-0003-0280-6318) elin.kronander@scilifelab.se\,  \n\n\n\nDavid Rayner (SND\, 0000-0003-0545-3634) david.rayner@gu.se URL:https://www.scilifelab.se/event/open-science-swedish-context/ LOCATION:Air&Fire\, SciLifeLab Stockholm\, Tomtebodavägen 23A\, Solna\, Sweden CATEGORIES:Course ORGANIZER;CN="Training Hub%2C NBIS%2C and SND":MAILTO:traininghub@scilifelab.se END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Stockholm:20250505T151500 DTEND;TZID=Europe/Stockholm:20250505T161500 DTSTAMP:20260404T104059 CREATED:20250128T103122Z LAST-MODIFIED:20250423T091703Z UID:10001462-1746458100-1746461700@www.scilifelab.se SUMMARY:[The Svedberg seminar] - Viral ecogenomics: exploring viral diversity and virus-host interactions from metagenomes DESCRIPTION:Simon RouxPhD\, Viral Genomics Group Lead DOE Joint Genome Institute\, Lawrence Berkeley National Laboratory\, USA \n\n\n\n \n\n\n\n \n\n\n\nBio\n\n\n\nDr. Roux lead the Viral Genomics group as part of the Metagenome program of the DOE Joint Genome Institute. Research in the group includes the development of tools and methods to explore viral diversity and the study of virus:host interactions in model soil and freshwater environments. The long-term goal his research is to understand the ecological and evolutionary drivers of virus:host dynamics in natural microbial communities and address questions such as “how do viruses spread and adapt across environments ?”\, “how do viruses take over and reprogram microbial cells ?”\, and “how do viral infections alter ecosystem processes ?”. \n\n\n\nViral ecogenomics: exploring viral diversity and virus-host interactions from metagenomes\n\n\n\nMicrobes are driving nutrient and energy transfers across the planet’s ecosystems\, but do so under strong constraints exerted by viruses. Over the last decade\, metagenomics revolutionized our ability to “see” viruses by providing large genome catalogs for uncultivated viruses\, enabling a better characterization of virus-host interactions and their impact on microbiomes. Here I will present our latest work in this field\, including (i) new approaches to maximize the recovery and annotation of viral genomes from metagenomes\, (ii) analysis of virus-host dynamics across seasons in a natural soil ecosystem based on paired metagenomes and metatranscriptomes\, and (iii) unexpected challenges in leveraging CRISPR spacer data to infer virus:host interactions. \n\n\n\n \n\n\n\n \n\n\n\n\n\n\n\nHost: Maliheh Mehrshad maliheh.mehrshad@slu.se SLU\, Luisa Hugerth luisa.hugerth@scilifelab.se UU URL:https://www.scilifelab.se/event/the-svedberg-seminar-simon-roux/ LOCATION:BMC Room C8:301\, Husargatan 3\, Uppsala\, Sweden CATEGORIES:Event ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2022/02/Picture1-The-Svedberg.png END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Stockholm:20250506T120000 DTEND;TZID=Europe/Stockholm:20250506T130000 DTSTAMP:20260404T104059 CREATED:20250416T120902Z LAST-MODIFIED:20250416T120941Z UID:10001533-1746532800-1746536400@www.scilifelab.se SUMMARY:Umeå seminar series: Cryo-focused ion beam milling (cryo-FIB-SEM): Taking you where you need to go DESCRIPTION:SciLifeLab Site Umeå/KBC Infrastructure Seminar Series \n\n\n\nSpeaker: Erin Schexnaydre\, Staff scientist\, Umeå Centre for Electron Microscopy (UCEM)\, Umeå University \n\n\n\nShort description: Cryo-focused ion beam milling (cryo-FIB) is a powerful technique. Its power comes from its versatility to study biological systems in vitro or in situ\, i.e. within cells or tissue. It has the ability to reach uncharted regions in biological systems. Cryo-FIB milling is used to expose 100–250 nm thin sections (called lamella) in intact frozen cells and tissue. The process allows access into the cells for high-resolution cryo-electron tomography (cryo-ET) and structure determination of biomolecules in their native environment. \n\n\n\nWebpage of Umeå Centre for Electron Microscopy (UCEM) \n\n\n\n\nRegistration: Sign up for the IRL seminar and reserve your free lunch (salad\, drink\, and a little sweet snack) by Friday\, 2 May\, 13:30: https://www.umu.se/en/research/infrastructure/scilifelab/scilifelab-site-umea–kbc-infrastructure-seminar-series Follow online (registration is not required): https://umu.zoom.us/j/69390567429 URL:https://www.scilifelab.se/event/umea-seminar-series-cryo-focused-ion-beam-milling-cryo-fib-sem-taking-you-where-you-need-to-go/ LOCATION:Glasburen Seminar Room\, Chemical Biological Centre (KBC) Building\, Umeå University\, Umeå\, 901 87\, Sweden CATEGORIES:Event ATTACH;FMTTYPE=image/webp:https://www.scilifelab.se/wp-content/uploads/2025/04/cryoet_workshop_image_16_9.jpg.webp ORGANIZER;CN="SciLifeLab Ume%C3%A5":MAILTO:umea@scilifelab.se END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Stockholm:20250508T120000 DTEND;TZID=Europe/Stockholm:20250508T130000 DTSTAMP:20260404T104059 CREATED:20250109T102820Z LAST-MODIFIED:20250505T132125Z UID:10001442-1746705600-1746709200@www.scilifelab.se SUMMARY:Campus Solna Seminar Series: Bartlomiej Porebski & Leo Dahl DESCRIPTION:Welcome to join the Campus Solna Seminar Series – an initiative to promote the fantastic science ongoing at Campus Solna and hopefully forge more internal communication and collaboration between within Campus Solna. The format consists of two 20 min talks (One speaker from the Alpha-building and one from the Gamma-building respectively)\, with an additional 5 min of questions. Presentation of ongoing (unpublished) projects is strongly encouraged. \n\n\n\nThe seminars are held Thursdays 12:00-13:00. You can bring your lunch to the seminar. \n\n\n\nPhD students that are attending the Campus Solna Seminar lectures will have the opportunity to gain credits. For the syllabus and instructions on how to obtain these credits\, read this document. Please contact your own department at your host University to confirm.See here the full schedule for this semester. \n\n\n\nThis week:\n\n\n\n\n\n\nBartlomiej Porebski\n\n\n\nOscar Fernandez-Capetillo – alpha 4 \n\n\n\nPhenotypic drug discovery in ALS \n\n\n\n\n\nLeo Dahl\n\n\n\nJochen Schwenk – alpha 2 \n\n\n\nIdentification of immune phenotypes in self-sampling citizens \n\n\n\n\n\n\nThis seminar series is organized by the PhD & Postdoc Council. For more information about the Council and other events check our page. URL:https://www.scilifelab.se/event/campus-solna-seminar-series-bartlomiej-porebski-emil-johansson/ LOCATION:Milkyway SciLifeLab Solna\, Tomtebodavägen 23\, Solna CATEGORIES:Community ATTACH;FMTTYPE=image/jpeg:https://www.scilifelab.se/wp-content/uploads/2022/09/IMG_20221103_120135408_HDR-scaled.jpg ORGANIZER;CN="SciLifeLab Solna PhD & Postdoc Council":MAILTO:phd-council@scilifelab.se END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Stockholm:20250509T110000 DTEND;TZID=Europe/Stockholm:20250509T120000 DTSTAMP:20260404T104059 CREATED:20250502T103048Z LAST-MODIFIED:20250502T130149Z UID:10001539-1746788400-1746792000@www.scilifelab.se SUMMARY:RNA profiling of cell types and cell states with FACS-seq DESCRIPTION:Clinical Genomics Webinar Series\n\n\n\nClinical Genomics Umeå is hosting this webinar as part of the webinar series by the Clinical Genomics Platform \n\n\n\n \n\n\n\njoin zoom webinar\n\n\n\nThis webinar will illustrate how our research group uses flow cytometry and RNA-seq in tandem\, to assess cell type diversity and the effects of treatments in purified cell populations. Some examples will be presented where intracellular antibodies were used to enrich for cell types\, followed by RNA-seq profiling. In addition\, some examples will be given of the application of FACS-seq to profile purified cell types with low-abundance starting material\, in the context of cancer research. \n\n\n\n \n\n\n\nEveryone is welcome so feel free to spread the details with anyone who may be interested. Hope to see you there! \n\n\n\nHost: Linda Köhn\, Head of Unit \n\n\n\nInvited speaker: Cedric Patthey\, Staff Scientist\, Umeå University URL:https://www.scilifelab.se/event/rna-profiling-of-cell-types-and-cell-states-with-facs-seq/ LOCATION:Online event via Zoom CATEGORIES:Event ATTACH;FMTTYPE=image/jpeg:https://www.scilifelab.se/wp-content/uploads/2025/05/Clinical-Genomics-Webinar-series.jpg END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Stockholm:20250512T150000 DTEND;TZID=Europe/Stockholm:20250512T160000 DTSTAMP:20260404T104059 CREATED:20250428T180742Z LAST-MODIFIED:20250428T180743Z UID:10001538-1747062000-1747065600@www.scilifelab.se SUMMARY:Chemical Biology Seminar Series with Kilian Huber DESCRIPTION:Welcome to a seminar with Kilian Huber in the Chemical Biology Seminar Series. \n\n\n\n“Chemical Biology Strategies for Target Discovery and Validation: Insights from Phenomics\, Proteomics\, and PROTACs” \n\n\n\nKilian HuberPhD & Senior Group Leader\, Chemical Biology & Chemical Probes\, University of Oxford \n\n\n\nWe will meet up with individuals who do not have access to SciLifeLab  in the reception at 14.50 \n\n\n\nZoom link URL:https://www.scilifelab.se/event/chemical-biology-seminar-series-with-kilian-huber/ LOCATION:Hybrid event in Gamma 2 lunchroom and zoom\, Tomtebodavägen 23 B\, Solna\, 17165\, Sweden CATEGORIES:Event END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Stockholm:20250512T151500 DTEND;TZID=Europe/Stockholm:20250512T161500 DTSTAMP:20260404T104059 CREATED:20250423T092440Z LAST-MODIFIED:20250424T080516Z UID:10001534-1747062900-1747066500@www.scilifelab.se SUMMARY:[The Svedberg seminar] Extracting meaning from high-throughput functional genomics data with Bayesian statistics DESCRIPTION:High-throughput functional genomics technologies have transformed infection biology into an increasingly data-driven science\, yet extracting meaningful insights from complex experiments remains challenging. Bayesian hierarchical modeling addresses these challenges by providing a framework to reason about the underlying data generating process. Here\, I illustrate the power of this approach through two case studies. First\, Bayesian modeling of RNA decay dynamics in Salmonella enterica identified confounding factors significantly biasing previous global RNA half-life estimates and revealed novel functions of bacterial RNA-binding proteins via transcriptome-wide differential stability analysis. Second\, we designed and analyzed a genome-wide transposon insertion screen for Shigella flexneri in a realistic human organoid infection model\, accounting for population bottlenecks and uncovering an unexpected role for bacterial tRNA modification enzymes in regulating virulence. I will end with an outlook on scaling our approach to very large datasets in the context of bacterial single-cell RNA-seq. \n\n\n\nLars Barquist\, Assistant Professor University of Toronto\, Canada \n\n\n\nHost: Maria Letizia Di Martino ml.dimartino@imbim.uu.se and Mikael Sellin mikael.sellin@imbim.uu.se \n\n\n\nBio\n\n\n\nLars received his PhD from Cambridge University for work on high-throughput and computational methods for studying pathogen evolution at the Wellcome Sanger Institute. After an Alexander von Humboldt postdoctoral fellowship\, he went on to start his own research group in 2018 at the Helmholtz Institute for RNA-based Infection Research in Würzburg\, Germany before recently moving to the University of Toronto. His work spans a broad range of topics at the interface of infection and computational biology\, ranging from large-scale comparative pathogen genomics and genotype-to-phenotype inference to detailed molecular studies of regulatory mechanisms and translational applications in antibiotic development. URL:https://www.scilifelab.se/event/the-svedberg-seminar-lars-barquist/ LOCATION:BMC Room C8:301\, Husargatan 3\, Uppsala\, Sweden CATEGORIES:Event ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2022/02/Picture1-The-Svedberg.png ORGANIZER;CN="The Svedberg Seminar Series":MAILTO:thesvedberg@scilifelab.uu.se END:VEVENT END:VCALENDAR