SciLifeLab

FAIR play: Mastering Metadata to Empower Life Scientists
2025-11-25 11:00 - 12:00 (Europe/Stockholm) | https://uu-se.zoom.us/j/62780940554?from=addon
Unlock the potential of your research by mastering meta(data) management in and the FAIR Data Principles—Findable, Accessible, Interoperable, and Reusable. This session offers practical guidance tailored for life scientists, focusing on best practices to organise and share your data effectively. The talk will focus on how good metadata practices can enhance collaboration, ensure reproducibility, and align your work with Open Science principles, ultimately increasing the impact of your research.

Presenter: Parul Tewatia, PhD, project coordinator (FAIR metadata and semantic technologies), SciLifeLab Data Centre

Recording: https://youtu.be/mc4BOOoLTMASlides: https://doi.org/10.17044/scilifelab.28615511

More information

This event is part of the SciLifeLab Open Science seminar series, an event series by the SciLifeLab Data Centre and NBIS joint Data Management team.The goal of the events in this seminar series is to provide interesting interactive seminars around topics related to Research Data Management and Open Science in general, and to foster discussions around best practices.

Research Data Management (RDM) concerns the organization, storage, preservation, and sharing of data that is collected and analyzed during a research project. Proper planning and management of research data will make project management easier and more efficient while projects are being performed. It also facilitates sharing and allows others to validate as well as reuse the data.Open Science is a set of principles and practices that aim to make scientific research from all fields accessible to everyone for the benefits of scientists and society as a whole. Open science is about making sure not only that scientific knowledge is accessible but also that the production of that knowledge itself is inclusive, equitable and sustainable.

The events are open to everyone working at or affiliated with a Swedish research institute or university. We welcome all researchers, educational professionals, staff, RDM professionals, and others with an interest in life sciences, from all university levels. The events are informal and inclusive, so feel welcome to join and participate in our interesting discussions!

The events will be recorded and published openly after the seminars on the SciLifeLab YouTube channel. The slides will be made available at our SciLifeLab Data Repository. More information about SciLifeLab Data Centre and NBIS joint Open Science seminar series: https://www.scilifelab.se/data/scilifelab-data-management-seminar-series/

If you have suggestions for topics or presentations, please contact us at data-management@scilifelab.seFor more information or inquiries, please contact us at data-management@scilifelab.se

[Spotlight Seminar Series] Molecular Mechanisms Underlying the Energy Currents of Life
2025-11-25 15:15 - 16:30 | Gamma 2 Lunchroom, SciLifeLab, Tomtebodavägen 23, Solna, Sweden
Spotlight seminar series proudly welcomes Professor Vile R. I. Kaila to give a seminar at SciLifeLab Campus Solna.

Biography

Ville R. I. Kaila received his PhD in biochemistry in 2009 from University of Helsinki. After a postdoc at the US National Institutes of Health (NIH), he was appointed a professorship at the Technical University of Munich in 2013. In 2019, Kaila moved with his research group to Stockholm, where he is currently professor at the Department of Biochemistry and Biophysics at Stockholm University and a Wallenberg Scholar. His research focuses on elucidating mechanistic principles of bioenergetic enzyme complexes by development of integrative computational and experimental approaches. Read more at http://villekaila.com/

Abstract

Biological energy conversion is catalyzed by intricate protein complexes that transduce redox energy into proton currents across a biological membrane, powering the cellular energy metabolism. Yet, despite significant advances in recent years, the molecular principles of these reactions remain poorly understood and pose major scientific challenges. In this talk, I describe our integrative mechanistic exploration of complex bioenergetic machines, where we combine multiscale simulations and data-driven methods with biophysical experiments and structural (cryo-EM) studies to derive a molecular understanding of intricate long-range charge transfer reactions in biology on a broad range of timescales and spatial resolutions. I describe our recent work on understanding enzymes catalyzing long-range charge transfer reaction by intrinsic electric field effects. We find that mutations of key residues mediating these allosteric processes lead to perturbed coupling effects, and development of severe human diseases, with striking similarities in different biological systems.

Host: Marta Carroni marta.carroni@scilifelab.se

NanoSIMS webinar series: Chemical bio-imaging using ToF-SIMS and OrbiSIMS
2025-11-26 15:00 - 16:00
This month’s Mass Spectrometry Imaging webinar will focus on chemical bio-imaging using ToF-SIMS and OrbiSIMS, what it is and where it is located, presented by Prof. David J. Scurr, the University of Nottingham, UK.

🕒 Time: 15:00–16:00 (presentation and discussion)☕ Followed by: Informal discussion with the speaker, 16:00–16:30📍 Format: Zoom

Zoom link

Meeting ID: 616 3655 5280Passcode: [REDACTED]

Speaker

Prof. David J. Scurr is a Principal Research Fellow at The University of Nottingham. He has pioneered the application of ToF-SIMS and OrbiSIMS in the field of pharmacy and biology. He obtained a BSc in Materials Science (2002) and PhD focusing upon materials characterisation (2005) at The University of Manchester. David’s research has a focus upon the implantation of novel data processing strategies, such as molecular formula prediction (MFP) [Edney et al. Anal. Chem. 2022].

His research highlights include the characterisation of biological samples using ToF-SIMS and OrbiSIMS, for example, breakthrough research into the in situ analysis of unlabelled proteins [Kotowska et al. Nature Comms, 2020] forming the basis of novel research in the development of proteomics / metabolomics, diseased tissue analysis and biomaterials at The University of Nottingham. Additionally, David’s research has demonstrated the ability of SIMS to characterise skin tissue and understand permeation mechanisms of xenobiotic chemistries (pharmaceutical, cosmetic, agrochemical and antibacterial) within complex tissues such as skin [Starr et al. PNAS, 2022].

Campus Solna Seminar Series: Koen Jurgens & Alana Panzenhagen
2025-11-27 12:00 - 13:00 | Milkyway SciLifeLab Solna, Tomtebodavägen 23, Solna
Welcome to join the Campus Solna Seminar Series – an initiative to promote the fantastic science ongoing at Campus Solna and hopefully forge more internal communication and collaboration between within Campus Solna. The format consists of two 20 min talks (One speaker from the Alpha-building and one from the Gamma-building respectively), with an additional 5 min of questions. Presentation of ongoing (unpublished) projects is strongly encouraged.

The seminars are held Thursdays 12:00-13:00. You can bring your lunch to the seminar.

PhD students that are attending the Campus Solna Seminar lectures will have the opportunity to gain credits. For the syllabus and instructions on how to obtain these credits, read this document. Please contact your own department at your host University to confirm.See here the full schedule for this semester.

This week:

Koen Jurgens

Marta Carroni – gamma 6

Structural basis for p97 and ataxin-3 interplay

Alana Panzenhagen

Ola Larsson – gamma 5

Uncovering mechanisms and organization underlying selective regulation of mRNA translation

This seminar series is organized by the PhD & Postdoc Council. For more information about the Council and other events check our page.

Multimodal explorative testing in the ON-OFF ibrutinib trial in CLL
2025-11-28 09:00 - 09:30 | Online event via Zoom
Multimodal explorative testing in the ON-OFF ibrutinib trial in CLLRichard Rosenquist Brandell, Karolinska Institutet & Karolinska University Hospital

Chronic lymphocytic leukaemia (CLL) is the most common leukaemia in the Western World and displays substantial variability in clinical course, ranging from indolent disease requiring no therapy to highly aggressive forms with short survival despite treatment. Although the past decade has seen major advances in drug development, CLL remains incurable. Targeted therapies, particularly Bruton’s tyrosine kinase inhibitors (BTKi), have become central to CLL management. However, continuous long-term BTKi administration, such as with ibrutinib, is associated with considerable significant side-effects, including cardiac arrhythmias. Furthermore, despite its proven efficacy in both treatment-naïve and relapsed/refractory CLL, resistance to ibrutinib continues to challenge durable disease control. To address these limitations, we conducted a phase 1b/2 prospective, single-arm, multicenter study evaluating controlled treatment cessation as a strategy to preserve tolerability and maintain sensitivity to ibrutinib, while also improving cost-effectiveness. The study protocol incorporated serial blood sampling prior to treatment initiation and throughout on/off treatment periods. Here, we leverage this unique longitudinal sample collection to perform multimodal profiling, including genomic and transcriptomic sequencing as well as proteomics, to investigate mechanisms of drug response and resistance. We provide an update on the current status of the study and ongoing analyses.

registration

Biography

Richard Rosenquist Brandell is Professor of Clinical Genetics at the Department of Molecular Medicine and Surgery, Karolinska Institutet, and Senior Physician in Clinical Genetics at Karolinska University Hospital, Sweden. Focusing on hematological malignancies and utilizing high-throughput sequencing and other innovative technologies, his research team has identified novel prognostic and predictive biomarkers that have refined disease classification and significantly improved patient risk-stratification and clinical decision-making. Richard Rosenquist Brandell initiated and led the Clinical Genomics Unit within Science for Life Laboratory (SciLifeLab) in Uppsala (2013-2017) and was platform director for the Clinical Genomics platform (2016-2021) within SciLifeLab, which includes seven Clinical Genomics units across Sweden. He is currently Director of Genomic Medicine Sweden (GMS), a national infrastructure for implementation of precision medicine. Rosenquist Brandell is a member of the Nobel Assembly at Karolinska Institutet.

[The Svedberg seminar] - Genome organisation and patterns of molecular evolution
2025-12-01 15:15 - 16:15 | BMC Room C8:301, Husargatan 3, Uppsala, Sweden
Jennifer James

Assistant Professor DDLS Fellow

Bio

Dr. Jennifer James did her PhD in population genetics with Adam Eyre-Walker at the University of Sussex. After a postdoctoral position at the University of Cambridge she moved to the US, where she worked as a postdoctoral researcher with Joanna Masel at the University of Arizona, which introduced her to the world of proteomics. She next moved to Uppsala and worked as a postdoctoral research fellow with Martin Lascoux prior to becoming a DDLS fellow and starting her own new research group in Molecular Evolution. Her group conducts research on patterns of molecular evolution both at the genome and proteome level, with a focus on understanding mutational robustness.

Genome organisation and patterns of molecular evolution

In my group, we try to understand patterns of phenotypic evolution at the proteome level, and molecular evolution across the genome. Key to this question is understanding how the genome is structured and organised. For example, how pleiotropic are the effects of genes on average, and how complex are gene networks? To give one case, if pleiotropy is universal, such that all genes affect all traits, we expect all new mutations to have the same effect on fitness. However, the extent of pleiotropy in real biological systems remains debated. In this seminar I will discuss our

Host: Siv Andersson siv.andersson@icm.uu.se, UU

Introduction to the Module System on Berzelius
2025-12-02 10:00 - 11:30 | Zoom
This training offers a practical introduction to the module system on Berzelius. The session will cover:

how to find modules on Berzelius

load/unload modules

use modules in interactive or batch modes

create your own module

Participants will also gain hands-on experience with these commands. By the end of the session, you will be able to navigate the modules system Berzelius confidently and use them effectively for your research.-on experience with these commands. By the end of the session, you will be able to navigate Berzelius confidently and use its resources effectively for your research.

Date: December 2, 2025Time: 10:00–11:30

Target audience: The online event is open for all current and prospective Berzelius users. Please read the eligibility requirements for accessing Berzelius.Place: Online via Zoom (link provided upon registration)

registration

Preliminary Agenda

TimeSession TitleSpeaker(s)10:00–11:00Introduction to the Module System on BerzeliusSoumi Chaki11:00–11:30Open Q&A SessionBerzelius Application Expert

This event is a collaboration between National Supercomputer Centre (NSC) at Linköping University and SciLifeLab Data Centre.

For questions please contact soumi.chaki@liu.se (Soumi Chaki)

Is high-throughput electrophysiology possible?
2025-12-02 13:00 - 14:00
Register here

On site seminar – Electrophysiology Infrastructure

Location: Jörgen Lehmann, Academicum, Medicinaregatan 3 and SciLifeLab Gothenburg

Presenters

Fredrik Elinder, Professor, Site director SciLifeLab Linköping, Chemical Biology Consortium Sweden (CBCS), and Department of Biomedical and Clinical Sciences (BKV), Linköping University

Nina Ottosson, Research Coordinator, Chemical Biology Consortium Sweden (CBCS), and Department of Biomedical and Clinical Sciences (BKV), Linköping University

The electrophysiology unit at Linköping University, part of Chemical Biology Consortium Sweden (CBCS) at SciLifeLab, visits site Gothenburg, and presents the infrastructure during a seminar.

During the day, 1-on-1 meetings with the presenters will be possible at The SciLifeLab office, Medicinaregatan 3. Take the chance to discuss how your research questions can be answered through analyses of ion channels. Request is added in the registration form.

The electrophysiology unit, a recent addition to SciLifeLab’s range of infrastructures, is equipped with automated patch-clamp instrumentation, and supports a wide range of electrophysiological studies involving both voltage-gated and ligand-gated ion channels, including pharmacological screening, cardiac safety assessments, and biophysical investigations.

WELCOME!

Fredrik Elinder and Nina Ottosson, Electrophysiologists

Josefine Sandström and Maria Smedh, SciLifeLab site coordinators Webpage of the CBCS Linköping node.

The NIH NIAID Blueprint: A FAIR Implementation Approach for the Biomedical Sciences
2025-12-03 16:30 - 17:30 | Online event via Zoom
SciLifeLab Data Centre welcome you to join us for the webinar “The NIH NIAID Blueprint: A FAIR Implementation Approach for the Biomedical Sciences” presented by Christine Kirkpatrick. Head – GO FAIR US, Secretary General – CODATA, Principal Investigator – NIAID Data Landscaping and FAIRification, San Diego Supercomputer Center, UC San Diego

When: Wednesday Dec 3, 16:30-17:30 CET (Zoom)

register here

As organisations adopt the FAIR Principles, many face challenges FAIRifying not just datasets but entire ecosystems. The National Institute of Allergy and Infectious Diseases (NIAID), an Institute within the US National Institutes of Health (NIH), manages a diverse data landscape across infectious, allergic, and immunologic domains.

Its FAIRification project aims to improve discovery and reuse across repositories with varied architectures, metadata maturity, and timelines. This work culminated in the recently released, “A Blueprint for Including Digital Objects in the NIAID Data Ecosystem.

This presentation describes the GO FAIR US–led assessment of NIAID repositories, highlighting:

Customized FAIR assessment instruments

Evaluation of record-based (not just file-based) repositories

Common assessment and progress tracking

Impact-driven adoption of metadata standards and PIDs

Improving citation practices

Adapting to social and project constraints

The approach builds on prior FAIR frameworks (FAIRsFAIR, RDA DMM, EarthCube, GO FAIR Foundation) and uses stakeholder-informed questionnaires and interviews to capture repository practices. Combining qualitative assessment and FAIR Implementation Profiles, the method establishes a FAIR baseline, guides targeted improvement strategies, and enables cross-repository comparison to inform strategic planning and strengthen community buy-in.

Organiser: SciLifeLab Data Centre For more information or inquiries please contact: datacentre@scilifelab.se

This project has been funded in whole or in part with Federal funds from the National Cancer Institute, National Institutes of Health, under Contract No. 75N91019D00024. The content of this publication does not necessarily reflect the views or policies of the Department of Health and Human Services, nor does mention of trade names, commercial products, or organizations imply endorsement by the U.S. Government.

User meeting for your multi-modal research projects
2025-12-04 09:00 - 10:30 | virtual event
Boost your research — Book a private SciLifeLab planning and feedback session for your multi-modal research projects!

Register here

Once we have received your registration, you will be sent the link to the online meeting.

Date: December 4, 9.00 – 10.30 Registration deadline: November 28

Multimodal molecular profiling and novel computational methods are transforming life science research, but also pose new challenges in study design, project resource planning and data management. SciLifeLab is a national resource of unique technologies and expertise available to life scientists, in areas such as biomedicine, ecology and evolution, aiming to bring scientists together across traditional boundaries and foster collaborations with industry, health care, public research organizations and international partners.

The first Thursday of every month at 9.00 (except July and August), SciLifeLab offers an opportunity to jointly meet with representatives across the SciLifeLab service platforms, to get feedback and help to plan, design, and refine new or ongoing multimodal research projects. Your project plans are discussed privately and remain confidential, and information will not be shared outside of the service platforms. Note that for most studies, follow-up meetings will be needed, but our aim for these meetings is to provide an easy-access entry point for an overarching planning of multimodal studies.

For studies focusing on a single technology only, please primarily contact our service platforms directly as described at the SciLifeLab homepage.

To make the best out of the allotted time, we ask you to provide some background information about your project, to help us ensure that the relevant experts are available to discuss your study.

3D Imaging in Health and Disease
2025-12-04 09:00 - 17:00 | Nobel Forum, Nobels väg 1, Solna, Sweden
Characterizing molecular and cellular complexities in 3D is an emerging field allowing to study biology in its true context.

In this symposium national and international experts will present developments and applications in 3D imaging aimed to improve health and disease analysis across scales

Please register by sending an e-mail to hans.blom@scilifelb.se

Program 3D symposiumDownload

Campus Solna Seminar Series: Nona Struyf & Iva Sutevski
2025-12-04 12:00 - 13:00 | Air&Fire, SciLifeLab Stockholm, Tomtebodavägen 23A, Solna, Sweden
Welcome to join the Campus Solna Seminar Series – an initiative to promote the fantastic science ongoing at Campus Solna and hopefully forge more internal communication and collaboration between within Campus Solna. The format consists of two 20 min talks (One speaker from the Alpha-building and one from the Gamma-building respectively), with an additional 5 min of questions. Presentation of ongoing (unpublished) projects is strongly encouraged.

The seminars are held Thursdays 12:00-13:00. You can bring your lunch to the seminar.

PhD students that are attending the Campus Solna Seminar lectures will have the opportunity to gain credits. For the syllabus and instructions on how to obtain these credits, read this document. Please contact your own department at your host University to confirm.See here the full schedule for this semester.

This week:

Nona Struyf

Brinton Seashore-Ludlow – alpha 4

FLT3 inhibitor response in AML is shaped by a progenitor-like cell state selectively targeted by SMAC mimetics

Iva Sutevski

Burcu Ayoglu – gamma 3

Leveraging spatial proteomics for molecular and single-cell insights into neurodegenerative diseases

This seminar series is organized by the PhD & Postdoc Council. For more information about the Council and other events check our page.

Discovery and developmentof GRK2-biased beta 2-adrenergic receptor agonists for the treatment of metabolic disorders
2025-12-05 10:15 - 11:00 | BMC Room C4:301, Husargatan 3, entrance C1, Uppsala, Sweden
Presenter: Dr Benjamin Pelcman, Atrogi AB

Atrogi AB is biotech company pioneering first-in-class treatments to revolutionize metabolic health. The talk will describe how targeting a novel GRK-biased b2-adrenergic receptor signaling pathway allows for the successful design of compounds useful in the treatment of disorders like type 2 diabetes (T2D), obesity and muscular wasting. The approach will be exemplified by the invention, selection and development of ATR-258, a b2-AR agonist that was developed for T2D and is about to enter phase 2 clinical trials. During the exploration of the chemical space, a diverse set of molecules were synthesized, and their effect on the downstream signaling will be discussed. In addition, the seminar will illustrate differences between drug development in Big Pharma and small biotech and the challenges of working in an environment with limited resources.

After receiving his Ph.D. in Organic Chemistry at KTH and a post doc session at Dartmouth College, NH, USA, Benjamin joined Astra Pain Control, first in Södertälje and then in Montreal, as a medicinal chemist. Benjamin has also held various positions at Pharmacia & Upjohn, Karo Bio, Biolipox and Orexo. After having started his own consultancy company, BeePCo, he came in contact with Atrogi where he was employed first as a CEO and later as Head of Chemistry and IP. Benjamin is now retired but is still working as a consultant for Atrogi and other small biotechs.

[The Svedberg seminar] - The origins of locally adaptive loci
2025-12-08 15:15 - 16:15 | BMC Room C8:301, Husargatan 3, Uppsala, Sweden
Gabriela Montejo-Kovacevich

Assistant Professor SciLifeLab Fellow Uppsala University

Bio

Gabriela Montejo-Kovacevich is a SciLifeLab fellow and Assistant Professor that recently established her lab at the Animal Ecology program in the Department of Ecology and Genetics at EBC (Uppsala University). Her group studies mechanisms that promote or constrain local adaptation. By integrating genomics with ecological and natural history approaches, mainly in insects, they explore the mode and tempo of evolution in natural populations.

The origins of locally adaptive lociHow do organisms evolve to inhabit diverse environments? This seminar explores the mode and tempo of evolution in the wild by studying local adaptation in three insect systems. I will first present work on Heliconius butterflies along a 1500m altitudinal gradient in the Andes, revealing strong, repeated selection at high-altitude, with evidence for adaptive introgression from pre-adapted species. I will then turn to a ‘megapest’ moth (Helicoverpa) that is threatening food security in Brazil through bidirectional adaptive introgression conferring insecticide resistance. Finally, I will introduce Euphydryas editha, a Californian butterfly capable of rapid, heritable shifts in host plant use offering a rare glimpse into ongoing behavioural adaptation to anthropogenic change. Together, these systems demonstrate how evolutionary forces interact to shape resilience in a rapidly changing world.

Host: Göran Arnqvist Goran.Arnqvist@ebc.uu.se, UU

Teaching and training as "communication": leveraging cognitive and communication theories to strengthen learning
2025-12-10 10:00 - 12:00 | Air&Fire, SciLifeLab Stockholm, Tomtebodavägen 23A, Solna, Sweden
Invited speaker: Professor Rochelle E. Tractenberg, Georgetown University

SciLifeLab as a Research Infrastructure incorporates people across a variety of technically complex fields. Staff-scientists and researchers often need to communicate about their complex work to people who are not fully familiar with all the details. Swedish universities offer training or support for scientists to help them communicate complex ideas for the public. However, we don’t often consider that these communication theories and strategies might be equally useful for promoting or strengthening a learning culture across the organization or that such communication strategies are useful in the training and teaching staff-scientists and researchers are involved in. This talk by Professor Tractenberg from Georgetown University will outline two theories – one for communication and one for change management – which have been augmented with cognitive theories so that they can optimize teaching and training and with this strengthen learning.

Welcome to a seminar where Professor Rochelle Tractenberg will present her recent work combining communication with change management strategies. We will learn how we can more efficiently can promote change around complex information – such as encouraging researchers to utilize a new method or tool, or instructing students about a complex aspect of the field they’re studying.

For registrants wishing to participate online, please indicate this in the registration form. For people attending onsite there will be a light lunch provided after the seminar.

Register here

Scientific abstract

Tractenberg’s augmented Diffusion of Innovation (aDOI, Tractenberg, 2023) is a theoretical framework for understanding and leveraging the cognitive complexity of messages so as to optimize uptake of the new information by any hearer. aDOI is adapted, through cognitive theory, from Rogers’ DOI communication model (1965/2003). A concrete, stepwise theory of change management (ToCM, Kotter 2012) originated in business, and has been widely used across business and leadership programs. This theory has also been augmented with cognitive theory (aToCM, Tractenberg 2024). Together, these two revised models provide a strategy for promoting change around complex information – such as encouraging scientists to utilize a new method or tool, or educating students about a complex aspect of the field they’re studying. Tractenberg’s augmented Diffusion of Innovation and Theory of Change Management make encouraging uptake of new ideas, or new knowledge, more consistent with human reasoning. These can support instructors’ adaptation of existing courses to include new information/technology or techniques, and can also help instructors to learn new evidence-based methods of teaching and assessing.

5th annual users meeting for integrated structural biology
2025-12-11 09:00 - 16:00 | Widerströmska Huset, Tomtebodavägen 18, Solna, Sweden
We welcome you to the 5th annual users meeting for integrated structural biology!

All users, future users and researchers interested in what structural biology can bring to your project are welcome!

As previous years, the symposium is held in Solna and specifically in Widerströmska huset, Tomtebodavägen 18a, room Charles.

Read more about structural biology here: https://www.scilifelab.se/servicearea/structural-biology/

registration

Registration deadline: Sunday, December 7

Agenda

Program_ISB_UsersMeeting2025Download

Campus Solna Seminar Series: Xiangyu Li & Oskar Kviman
2025-12-11 12:00 - 13:00 | Milkyway SciLifeLab Solna, Tomtebodavägen 23, Solna
Welcome to join the Campus Solna Seminar Series – an initiative to promote the fantastic science ongoing at Campus Solna and hopefully forge more internal communication and collaboration between within Campus Solna. The format consists of two 20 min talks (One speaker from the Alpha-building and one from the Gamma-building respectively), with an additional 5 min of questions. Presentation of ongoing (unpublished) projects is strongly encouraged.

The seminars are held Thursdays 12:00-13:00. You can bring your lunch to the seminar.

PhD students that are attending the Campus Solna Seminar lectures will have the opportunity to gain credits. For the syllabus and instructions on how to obtain these credits, read this document. Please contact your own department at your host University to confirm.See here the full schedule for this semester.

This week:

Xiangyu Li

Adil Mardinoglu – alpha 6

Oskar Kviman

Jens Lagergren – gamma 6

This seminar series is organized by the PhD & Postdoc Council. For more information about the Council and other events check our page.

Science & SciLifeLab Prize Scientific Symposium 2025
2025-12-11 13:00 - 16:00 | Auditorium Stockholm, Grand Hôtel, Södra Blasieholmshamnen 8, Stockholm, 10327, Sweden
Welcome to the Scientific Symposium where the winners of the 2025 Science & SciLifeLab Prize for Young Scientists will present their research!

Science, the American Association for the Advancement of Science (AAAS), and SciLifeLab joined forces in 2013, creating the Science & SciLifeLab Prize for Young Scientists to recognize excellence amongst young researchers from around the world. A global Prize aimed at rewarding scientists at an early stage of their careers.

The Prize is awarded in four different categories and the winners will be announced on November 14th

Uche Medoh, Grand Prize Winner in Molecular Medicine

Liam Lachs, Category Winner in Ecology and Environment

Nitzan Tal, Category Winner in Genomics, Proteomics, and Systems Biology Approaches

King L. Hung, Category Winner in Cell and Molecular Biology

All four winners of the Science & SciLifeLab Prize for Young Scientists are invited to Sweden December 8-13 to participate in a unique week filled with events in honor of science. They will have the opportunity to meet with leading scientists in their field of research and create life-long connections to support their careers.

The symposium will take place at beautiful Grand Hôtel in Stockholm.

Seats are limited so register today for your chance to meet with the winners and the the AAAS/Science editor team AND our honorary guest, the Grand Prize Winner from 2013, Professor Daniel Streicker.

Prize symposium 2025_programDownload

Prize_speaker biographies_2025Download

Registration

Read more about the Prize

Read more about the winners

[The Svedberg seminar] - Optogenetic control of gene expression dynamics in single cells
2025-12-15 15:15 - 16:15 | BMC Room C8:301, Husargatan 3, Uppsala, Sweden
Mary Dunlop

Professor Boston University, USA

Bio

Mary Dunlop is a Professor of Biomedical Engineering and Dorf-Ebner Distinguished Faculty Fellow at Boston University. She holds additional affiliations in Bioinformatics and Molecular Biology, Cell Biology & Biochemistry. She graduated from Princeton University with a B.S.E. in Mechanical and Aerospace Engineering and a minor in Computer Science. She then received her M.S. and Ph.D. in Mechanical Engineering from the California Institute of Technology. In recognition of her outstanding research contributions, she has received many honors including election as an AIMBE Fellow, the NSF Transitions Award, ACS Synthetic Biology Young Investigator Award, DOE Early Career Award, and NSF CAREER Award. She is also the recipient of several mentoring and teaching awards, including Boston University’s Award for Excellence in Mentoring Postdocs and the College of Engineering Teaching Excellence Award.

Optogenetic control of gene expression dynamics in single cells

Emerging approaches that integrate optogenetics with feedback control are transforming our ability to precisely manipulate microbial gene expression dynamics. In this talk, I will present how we harnessed deep neural networks and model predictive control to impose real-time, cell-specific gene expression patterns in bacteria, revealing crucial links between dynamic regulation and functional outcomes such as antibiotic resistance. I will also highlight our use of optogenetic tools and information theory to understand how variable expression of a key transcription factor influences downstream stress response genes and impacts bacterial survival under antimicrobial stress. These approaches provide new insights into the significant roles of cellular heterogeneity and dynamic regulation, advancing our understanding of gene expression and microbial behavior at the single-cell level.

Host: Daniel Jones daniel.jones@icm.uu.se, UU

SciLifeLab PULSE - information webinar for applicants
2025-12-18 00:00 - 23:59 | Online event via Zoom
This webinar (two time options available) gives PULSE applicants an opportunity to receive information on e.g. the matchmaking and application process, as well as eligibility rules. There will also be time for Q&A:s. Find out more about the SciLifeLab PULSE postdoc program here The 2nd SciLifeLab PULSE Call opened on December 15!

Webinar registration

Webinar on December 18, 2025, at 09:00 am, UTC+1

Register here

Webinar on December 18, 2025, at 16:00 pm, UTC+1

Register here

Unlocking Precision Health: From Molecular Insights to Clinical Impact in Complex Diseases
2026-01-23 09:00 - 17:00 | Operaterassen, Karl XII:s Torg, Stockholm, Sweden
The 3rd Symposium on Complex Diseases

Join us for an exciting day dedicated to advancing precision health and tackling the challenges of complex diseases. This symposium brings together leading researchers, clinicians, and industry to explore how molecular insights can transform clinical practice and improve patient outcomes.

For information about the symposium in Swedish: Unlocking Precision Health: From Molecular Insights to Clinical Impact in Complex Diseases (Swe).

Confirmed Speakers:

Oskar Frisell, Karolinska Institutet

Andrea Ganna, University of Helsinki, Finland

Lina Jonsson, University of Gothenburg

Richard Landberg, Chalmers University of Technology

Tuuli Lapalainen, KTH Royal Institute of Technology

Ruth Loos, University of Copenhagen, Denmark

Olle Melander, Lund University

Richard Rosenquist Brandell, Karolinska Institutet

Peter Würtz, Nightingale Health, Finland

Registration

Register via this form: https://forms.gle/6C7QzrzxwJ9NBPjd8. Registration deadline: 15 January 2026

Abstract Submission deadline: 5 January 2026

Why attend?

Expand your expertise in genomics, multi-omics, and precision medicine.

Network with experts and peers across academia, healthcare, and industry.

Participate in rapid talks, poster sessions, and lively discussions.

Metabolomics in Life Science
2026-01-27 08:00 - 2026-01-28 15:00 | Väven, Storgatan 46A, Umeå, 90326, Sweden
After the great success of the 2024 Metabolomics in Life Science conference, the Organizing Committee is thrilled to announce the second edition in 2026!Date: 27-28 January, 2026Venue: Vävenscenen, Umeå

Umeå University warmly invites you to Metabolomics in Life Science 2026, showcasing the latest NMR- and MS-based metabolomics research from Sweden, the Nordics, and beyond. The conference brings together researchers from around the world to share knowledge and discuss advances in areas like clinical and precision medicine, plant metabolomics, spatial and single-cell metabolomics, multi-omics, and computational/AI applications.

The event is organized by SciLifeLab platforms in Umeå: Swedish NMR Centre (SNC), Swedish Metabolomics Centre (SMC), and Computational Analytics Support Platform (CASP).

The program includes six keynote speakers from leading institutions, plus an industry exhibition showcasing the latest technologies and services in metabolomics research.

Registration is now open – Register here

Questions? Contact:

Ilona Dudka – ilona.dudka@umu.se

Kate Bennett – katie.bennett@umu.se

Looking forward to welcoming everyone in Umeå in January 2026!

Read more

OrganizersSwedish Metabolomics Centre (SMC)

NMR Core facility

Computational Analytics Support Platform (CASP)

SBDI Days 2026 -Artificial Intelligence in Ecology and Biodiversity Research
2026-02-10 08:30 - 2026-02-11 17:00 | Swedish Museum of Natural History, Frescativägen 40, Stockholm, Stockholm, 114 18, Sweden
Artificial Intelligence is no longer just a tool. It is becoming a vital partner in the quest to understand and protect biodiversity. SBDI Days 2026 will explore this transformative partnership under the theme: AI and Biodiversity: a Perfect Pair!

The Planetary Biology Strategic Area is pleased to team up with the Swedish Biodiversity Data Infrastructure (SBDI) for this event that dives deep into the future of Ecology and Biodiversity Research.

Highlights of the program:

Talks on using AI in Biodiversity Research and monitoring, pros, cons and ethics

Poster sessions

Workshops on FAIR data principles, tools to integrate biodiversity monitoring data from different platforms, building AI applications within ecology and biodiversity, and using eDNA data within the SBDI.

Early career researchers are warmly encouraged to present their work.

Abstract submission for poster or oral presentation are open till December 15, 2025.

Check out the conference website to dive into the program and register

Conference website

AI Agents in Life Sciences (in Stockholm)
2026-03-05 10:00 - 15:30 | Air&Fire, SciLifeLab Stockholm, Tomtebodavägen 23A, Solna, Sweden
We are delighted to invite you to join our upcoming workshop on “AI Agents in Life Sciences”, organized by SciLifeLab Data Centre. AI agents are emerging as autonomous systems that orchestrate scientific workflows by interacting with digital tools and data sources. These have various implications for life science research. They can, for example, simplify complex analyses by automating data integration, run computational models, and coordinate experimental steps, making research pipelines more efficient and reproducible. In this onsite workshop held at Air & Fire, SciLifeLab building in Solna, we will introduce and discuss AI Agents in life science, and engage in collaborative practical sessions. Welcome!

Date: 2026-03-05Time: 10.00-15.30 (coffee will be served from 9.30). Fika and lunch provided free of charge. Location: room Air & Fire, SciLifeLab, Tomtebodavägen 23, Solna. No remote participation.

Target audience: Researchers and PhD students interested in learning more about and trying hands-on exercises with AI Agents. Participants with any university affiliation and industry researchers are welcome. Basic Python programming skills, previous experience working with Jupyter notebooks would be helpful. Participants must bring their own laptop.

Speakers and Facilitators: Chris Long Huynh (PhD candidate, Uppsala University), and Mahbub Ul Alam and Johan Alfredéen (Data Engineers (AI) at SciLifeLab Data Centre).

The workshop will feature a series of engaging presentations, interactive discussions, and collaborative sessions focusing on:

Introduction to AI agent technologies

Applications, opportunities and challenges of AI Agents in life science

Hands-on tutorials with reasoning models, LangChain and MCP servers

Discussions on the role of AI agents in shaping the future of life science

Agenda

09:30-10:00 Light breakfast and networking

10.00-10.15 Presentation session 1: Introduction: Exploring how AI agents can transform life sciences. Speaker: TBA.

10.15-10.30 Demonstration Session: AI agents in action. Facilitators: Johan Alfredéen, Dinh Long Huynh.

10:30-12:00 Hands-on Session 1: Developing AI agents with LangChain & ReAct. Session Facilitators: Dinh Long Huynh, Mahbub Ul Alam.

12:00-13:00 Lunch and networking

13:00-13:30 Continuation of Hands-on Session 1: Developing AI agents with LangChain & ReAct.

13:30-15:00 Hands-on Session 2: AI agent collaboration with the Model Context Protocol (MCP). Session Facilitators: Mahbub Ul Alam, Johan Alfredéen, Dinh Long Huynh.

15:00-15:15 Presentation Session 2: Deploying AI Agents: Legal, Technical, and Practical Considerations. Speaker: Johan Alfredéen.

15:15-15:30 Concluding Session: Open Q&A

15:30 Fika and networking

Registration: Please add dietary restrictions to your registration. If you cannot join please cancel your registration. Please register with your SciLifeLab or university email.

Registration

This event is a organised by SciLifeLab Data Centre. For questions please contact serve@scilifelab.se .

Artificial intelligence and data-driven approaches for addressing the global challenge of antibiotic resistance
2026-03-11 12:00 - 2026-03-12 13:00 | Norrlands Nation Fest and Conference
Join the Data-driven Epidemiology and Biology of Infection research area (DDLS, Sweden) and the Flemming Initiative (UK) for an inspiring lunch-to-lunch meeting filled with science, networking, and discussions.

Infections caused by antibiotic-resistant bacteria are increasing, leading to millions of deaths and rising societal costs. Eighty years after Alexander Fleming was awarded the Nobel Prize for his discovery of penicillin, we are still confronted with the urgent challenge of diminishing antibiotic effectiveness. This symposium will explore how artificial intelligence and other data-driven approaches can provide new strategies to combat the growing threat of antibiotic resistance.

The DDLS research area symposia series aims to engage and promote the national scientific community around the DDLS research themes. The symposia bring together researchers, industry, and healthcare to stimulate collaboration and push the frontiers of data-driven life science. The events are open for everyone interested in data-driven research to participate.

This event is jointly organized by the Data-Driven Life Science program (DDLS, Sweden) and Imperial College (UK), and is hosted by SciLifeLab and the Knut and Alice Wallenberg Foundation.

Registration opening soon!

Date: 11-12 March 2026Time: lunch-to-lunchVenue: Norrlands Nation Fest and Conference, Västra Ågatan 14, 753 09 Uppsala

Confirmed Speakers

Laura Carroll, Umeå University, Sweden

David Aanensen, Oxford University, UK

Carolina Wählby, Uppsala University, Sweden

Daudi Jjingo, Makerere University, Kampala, Uganda

Damien Ming, Imperial College London

Kaisa Thorell, University of Gothenburg, Sweden

David Lund, Chalmers University of Technology, Sweden

Suzanne Ruhe-van der Weff, Karolinska Institutet, Sweden

Nina Zhu, Imperial College, UK

Sanjiv Sharma, Liverpool University, UK

Christian Giske, Karolinska Institutet, Sweden

Mauricio Barahona, Imperial College, UK

Anna Johnning, Chalmers University of Technology, Sweden

Nick Moser, Google DeepMind, UK

Organizing Committee

Erik Kristiansson, Chalmers University of Technology/University of Gothenburg’Alison Holmes, Imperial College LondonLaura Carroll, Umeå UniversityDamien Ming, Imperial College LondonJohan Elf, Uppsala UniversityAmish Acharya, Imperial College London

Questions can be answered by the Organizing Committee or events@scilifelab.se

Read more about the research area.

Read more about the Fleming Initiative.

Swedish Bioinformatics Workshop 2026
2026-03-12 09:30 - 2026-03-13 17:15 | Conference Centre Wallenberg, Medicinaregatan 20A, Gothenburg, 413 90, Sweden
The Swedish Bioinformatics Workshop (SBW) is an annual event organised by different Swedish universities since 2000, and is the largest gathering of bioinformaticians and computational biologists in Sweden. The meeting welcomes participants from all career stages and sectors, with a strong focus on PhD students and postdocs.

The programme will feature keynote presentations, contributed talks, hands-on workshops, and a poster session, with national and international speakers. SBW2026 aligns with the Nordic Computational Biology week.

Programme at a glance

Two full days of talks, six themed sessions, and a dedicated poster session

Four hands-on workshops

Networking opportunities with national and international keynote speakers

Keynote topics

Translational research

Multi-omics

Single-cell technologies

Cancer genomics

Machine learning / AI

Metagenomics

Parallell Workshop Sessions (onsite participation only)

Data Management

Academic Writing

Data Visualization

Bacterial Genomics

Event web page and registration

More information can be found at the event web page.

Event web page

Registration

Registration fees

Participant typeEarly-bird (Dec 1, 2025) RegularStudents* / Postdocs at a Swedish UniversityFreeFreeOther academic participants1,000 SEK2,000 SEKNon-academic participants2,000SEK3,000 SEKOnline** Students / Postdocs at a Swedish UniversityFreeFreeOnline** other participants——-500 SEK

* Students include all PhD students as well as Master’s students in their final thesis year.

** Zoom link will be sent via e-mail.

Important dates

Deadline for abstract submission: December 12, 2025

Deadline for onsite registration: January 12, 2026

Deadline for cancellation: February 23, 2026

Deadline for online registration: February 26, 2026

Data Driven Systems Biology: Harnessing Big Data and Systems Approaches to Decode Complex Biology
2026-03-24 09:00 - 2026-03-25 17:00 | Life City, Solnavägen 3H, Stockholm, 113 64
In the era of high-throughput technologies and rapidly expanding biomedical datasets, the field of systems biology is undergoing a transformative shift. The Data-Driven Systems Biology conference brings together leading researchers who are leveraging computational, statistical, and systems-level approaches to integrate and interpret complex biological data. This conference will explore how multi-omics, single-cell technologies, and spatial profiling, combined with advanced computational modeling and machine learning, are reshaping our understanding of dynamic biological systems.

The DDLS research area symposia series aims to engage and build a strong national scientific community around the DDLS research themes. Each of the four areas arranges two symposia per year. Everyone interested in data-driven research is welcome to take part. We aim to unite researchers, industry, and healthcare to foster collaboration and advance the frontiers of data-driven life science.

Target Group: The DDLS research area Expert Group in Cell and Molecular Biology invites all interested in Data-driven life science to meet, present, interact, and discuss Imaging in Cell and Molecular Biology.

The event will take place at Life City, Solna, Stockholm, and will include presentations from international and national invited speakers and selected abstracts. The event is free of charge.

Organized by:

Arne Elofsson and Eduardo Villablanca, DDLS Expert Group in Cell and Molecular Biology.

Contact:

events@SciLifeLab.se

Register here

Confirmed speakers

Alfonso Valencia, Barcelona Supercomputing Center, Spain

Avlant Nilsson, KI

Camilla Engblom, KI

Carsten Hopf, Heidelberg University, Germany

Erik Sonnhammer, Stockholm University

Jean Hausser, KI

Katerina Despoina Nastou, Statens Serum Institut, Denmark

Lucy Colwell, University of Cambridge, UK

Marcel Tarbier, Uppsala University

Mika Gustafsson, Linköping University

Simon Koplev, KTH

Program

March 24, 2026

11:30Registration and Network Lunch12:30Session 1; Systems Immunology14:50Coffee break15:30Session 2; Systems Precision Medicine17:30Poster session, Campus Solna, Delta.

March 25, 2026

08:30Doors open to the Lecture Hall, please be seated by 08:4508:45Session 3; Predictive models09:50Coffee Break12:15Network lunch13:30End of Conference

Flyer – Spread the word!

Please, spread the word about the Conference.

DDLS CMB March 2026_EEDownload

SciLifeLab Day Gothenburg 2026
2026-04-17 08:00 - 17:00 | RuNan, Chalmersplatsen 1, Gothenburg, 412 58, Sweden
Save the date!

Welcome to an inspiring full-day event bringing together researchers, experts, infrastructure representatives, and partners from across Sweden! SciLifeLab Day Gothenburg 2026 offers a unique meeting place for anyone working with – or curious about – advanced molecular life sciences, data-driven research, and translational innovation.

Throughout the day, you’ll experience visionary talks, insights into cutting-edge research infrastructures, real-world use cases from industry and healthcare, and plenty of opportunities for networking. The program includes everything from flash talks and poster sessions to discussions on how SciLifeLab technologies are driving progress in academia, healthcare, and industry.

Event highlights include:

SciLifeLab’s future outlook with SciLifeLab Director Jan Ellenberg

A regional perspective on SciLifeLab’s role in western Sweden

Presentations from national infrastructures and platforms

Sessions focused on clinical translation and industrial applications

Data-driven life science and success stories from the SciLifeLab Data Centre

Poster exhibitions, mingling, and engaging discussions

Don’t miss the opportunity to dive into the latest developments in Swedish life science, make new connections, and explore the wide range of possibilities SciLifeLab offers for research and innovation. We look forward to welcoming you to a day full of inspiration and new insights!

Research Opportunities at the Intersection of Society, Life Sciences, and Technology
2026-05-07 08:00 - 2026-05-08 17:00 | Uppsala Konsert & Kongress, Vaksala torg 1, Uppsala, 75331, Sweden
A Joint Conference between DDLS, WASP and WASP-HS

Uniting Sweden’s life science, machine learning and artificial intelligence communities, we welcome researchers from all disciplines to explore new research opportunities in a changing world.

Participants will have the opportunity to network, be inspired by excellent international keynote speakers, and take part in the latest research in Sweden. In addition to plenary keynotes, the program will offer a panel discussion, a poster session and ample time to mingle.

Practical Details

Dates

May 7-8, 2026

Venue

Uppsala Konsert & Kongress

Program

TBD

Background

Wallenberg AI, Autonomous Systems and Software Program (WASP), the SciLifeLab and Wallenberg National Program for Data-Driven Life Science (DDLS), and Wallenberg AI, Autonomous Systems and Software Program – Humanity and Society (WASP-HS) are collaborating through joint research projects and events with the ultimate goal of solving ground-breaking research questions across disciplines.

KI-SciLifeLab Symposium 2026
2026-05-07 12:00 - 18:00
Save the date!

The 5th edition of the KI-SciLifeLab Symposium will take place on May 7, 2026.

Venue, program (~12:00-18:00), and registration link will be announced early 2026.

The annual KI-SciLifeLab Symposium is organized by the SciLifeLab Committee at KI and aims at bringing together members of the SciLifeLab community at KI. Anyone else interested in our work and the program is also very welcome!
