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BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20210531T080000
DTEND;TZID=Europe/Stockholm:20210611T170000
DTSTAMP:20260404T001250
CREATED:20210413T071434Z
LAST-MODIFIED:20210526T120645Z
UID:10000355-1622448000-1623430800@www.scilifelab.se
SUMMARY:Super-Resolution\, Light-Sheet\, STED-FCS and FRET-FCS
DESCRIPTION:The Advanced Light Microscopy Unit\, ALM\, at Scilifelab gives a two-week course focusing on four new imaging and fluorescence spectroscopy techniques: \n\n\n\nLight-Sheet Imaging\n\n\n\nLong time-lapse imaging of live model organisms with low phototoxicityUltrafast volumetric imaging of cells with lattice light-sheet microscopy\n\n\n\nSuper-Resolution Imaging in Living Cells – MoNaLISA\n\n\n\nSmart probes. 50 nm resolution at 1-2 Hz. 100 x 100 mm field of view. Time lapse imaging\n\n\n\nSTED-FCS\n\n\n\nFluctuation spectroscopy with 30 nm resolutionSub-diffraction dynamics in living cells\n\n\n\nFRET-FCS\n\n\n\nEasy detection of protein-protein interactions in living cellsHighly sensitive detection of rare oligomers in living cells\n\n\n\nLecturers\n\n\n\nSteven EdwardsErdinc SezginIlaria TestaStefan Wennmalm\n\n\n\nCredits: 3 hp for PhD students\, but open for anyone \n\n\n\nLocation: Web-based \n\n\n\nRegistration: stewen@kth.se
URL:https://www.scilifelab.se/event/super-resolution-light-sheet-sted-fcs-and-fret-fcs/
CATEGORIES:Course
ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2019/10/microscope.png
ORGANIZER;CN="Advanced Light Microscopy Unit":MAILTO:stewen@kth.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20210602T090000
DTEND;TZID=Europe/Stockholm:20210602T130000
DTSTAMP:20260404T001250
CREATED:20210503T135504Z
LAST-MODIFIED:20210528T132452Z
UID:10000372-1622624400-1622638800@www.scilifelab.se
SUMMARY:Using the national infrastructures to solve antimicrobial resistance
DESCRIPTION:The first InfraLife workshop gathers stakeholders in the field of antimicrobial resistance (AMR) for a joint discussion on June 2nd\, 2021.  \n\n\n\nThe AMR workshop in June will be followed up by activities during Fall to focus and expand initiatives of relevance identified during initial discussions and the first workshop.  \n\n\n\nAs with other InfraLife initiatives – we invite all interested to reach out and be in touch if you want to hear more and see potential to get involved in activities! \n\n\n\nNew collaborations advancing science are about gathering cross sectorial experts and stakeholders around a grand challenge\, taking a thematic approach and engaging the infrastructures and available technologies in how they can help address the question and be part of the solution to the research challenge at hand. And showing the complementarities of the research infrastructures in this setting. \n\n\n\nWe plan for other future themes besides AMR\, such as lifestyle diseases/ cancer and clean water/ the Baltic Sea\, considering life sciences beyond human health including environmental challenges. If you are active in these areas within your organization and see potential for joint efforts\, please be in touch. We would love to hear from you and learn about the scientific questions and challenges of particular interest\, where you would like to get engaged to jointly explore the potential of the national research infrastructures. \n\n\n\nRegister to receive zoom link\n\n\n\n   \n\n\n\nProgram\n\n\n\n09:00Welcome remarksPia Kinhult\, moderator Olli Kallioniemi\, SciLifeLab Marjolein Thunnissen\, MAX IV Andreas Schreyer\, ESS09:20Current State of Affairs –  What have we learnt and where are we going?Anders Karlén Uppsala University09:40 SciLifeLab units and capabilitiesAnnika Jenmalm-Jensen\, SciLifeLab10:00Large-scale DNA sequencing and the AMR challenge: examples from CAReJoakim Larsson\, Göteborgs universitet10:15Short break10:20Life Science opportunities at MAXIVSelma Maric MAX IV10:40A taste of bio-imaging at MAX IVKarina Thånell\, MAX IV10:55Structural Biology at the European Spallation SourceEsko Oksanen\, ESS11:15Short break11:20Industry perspective Susanna Abrahmsén-Alami\, AstraZeneca11:40Round table discussion   Discussion topics: What are the most urgent needs for different stakeholders? How can different funding streams be utilized for AMR? How do we ensure a steady flow through all stages of development? How can the infrastructures be of use in the scientific\, diagnostic\, regulatory challenges of AMR?    12:50Conclusions and actionable projects  to address gaps in AMRPia Kinhult13:00End of Meeting
URL:https://www.scilifelab.se/event/using-the-national-infrastructures-to-solve-antimicrobial-resistance/
CATEGORIES:Event
ATTACH;FMTTYPE=image/jpeg:https://www.scilifelab.se/wp-content/uploads/2021/05/Infralife-square.jpg
ORGANIZER;CN="InfraLife":MAILTO:events@scilifelab.se
LOCATION:https://www.scilifelab.se/event/using-the-national-infrastructures-to-solve-antimicrobial-resistance/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20210603T130000
DTEND;TZID=Europe/Stockholm:20210603T140000
DTSTAMP:20260404T001250
CREATED:20210503T144211Z
LAST-MODIFIED:20210518T122326Z
UID:10000380-1622725200-1622728800@www.scilifelab.se
SUMMARY:Campus Solna Seminar Series: Trang Le and Aswathy Kallazhi
DESCRIPTION:Introducing the new Campus Solna Seminar Series – a new initiative to promote the fantastic science ongoing at Campus Solna and hopefully forge more internal communication and collaboration between the alpha and gamma buildings. The format will be 2 short 15 min talks (1 speaker from alpha and 1 from gamma)\, with an additional 5 min of questions. Presentation of ongoing (unpublished) projects is strongly encouraged. \n\n\n\nThe seminars are held Thursdays 13:00-13:50 and following current regulations\, they will be broadcast via zoom. \n\n\n\n\n\n\nTrang Le\n\n\n\nModelling the spatial cell cycle with deep learning \n\n\n\nEmma Lundberg – Alpha 2 \n\n\n\n\n\nAswathy Kallazhi\n\n\n\nLon-mediated proteolysis in Pseudomonas aeruginosa pathogenicity \n\n\n\nKristina Jonas – Gamma 5 \n\n\n\n\n\n\nRegister to receive the zoom-link. The same zoom link applies for all Campus Solna Seminar Series\, i.e. only one registration is necessary. \n\n\nPlease select a valid form
URL:https://www.scilifelab.se/event/campus-solna-seminar-series-trang-le-and-aswathy-kallazhi/
CATEGORIES:Community
ORGANIZER;CN="SciLifeLab Solna PhD & Postdoc Council":MAILTO:phd-council@scilifelab.se
LOCATION:
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20210604T130000
DTEND;TZID=Europe/Stockholm:20210604T134500
DTSTAMP:20260404T001250
CREATED:20210518T091847Z
LAST-MODIFIED:20210520T115320Z
UID:10000387-1622811600-1622814300@www.scilifelab.se
SUMMARY:Drug Discovery Seminars: An adaptable Drug Affinity Conjugate (ADAC) targeting CD40
DESCRIPTION:Proof of Concept and Pharmaceutical profiling\n\n\n\nSara Mangsbo\, Uppsala University\n\n\n\nAbstract: \n\n\n\nMuch attention has focused on developing CD40 directed agonistic monoclonal antibody therapy. Monoclonal antibodies targeting CD40 have been profiled for their epitope specificity and isotype in relation to their agonistic potential. Still\, clinical impact relies on a well-balanced clinical efficacy versus target-mediated toxicity. As CD40-mediated immune activation must rely on a combination of stimulation of antigen-presenting cells alongside antigen-presentation\, for efficient T cell priming\, alternative approaches to improve the therapeutic outcome of CD40-targeting strategies should focus on providing optimal antigen presentation together with CD40 stimulation. We have developed a bispecific antibody targeting CD40 as a means to carry in cargo (herein synthetic peptides) into antigen-presenting cells through a non-covalent\, high-affinity interaction between the antibody and the cargo peptide\, further referred to as the Antibody Drug Affinity Conjugate (ADAC) technology. The ADAC can improve both CD4+ and CD8+ T cell expansion in vitro and significantly improve CD8+ T cell proliferation in vivo. In addition\, the strategy leads to a stabilization of the half-life of the synthetic peptide. Future applications of ADAC involve pandemic preparedness to viral genetic drift as well as neoepitope vaccination strategies where the bispecific antibody is an off-the-shelve product\, and the peptide antigen is synthesized based on next-generation sequencing data mining.  \n\n\n\nA short speaker biography: \n\n\n\nSara Mangsbo (PhD) is Associate senior lecturer in antibody drugs and Associate professor in Experimental clinical immunology at Uppsala University. Dr Mangsbo earned her PhD in 2010 in cancer immunotherapy at Uppsala University and has since then focused her research on antibody-based drug delivery and synthetic long peptides and was recently awarded the SITC team award within the SLP stream. She is a serial entrepreneur and has founded Immuneed AB\, a service provider of immunotoxicity measurements in human whole blood. She is the Chief Development Officer of Ultimovacs and the co-founder of Vivologica AB and STRIKE pharma AB.  She drives a translational research project with the ambition and track-record of taking research projects into clinical trial testing.   \n\n\n\nRegistration
URL:https://www.scilifelab.se/event/an-adaptable-drug-affinity-conjugate-adac-targeting-cd40-proof-of-concept-and-pharmaceutical-profiling/
CATEGORIES:Event
ATTACH;FMTTYPE=image/jpeg:https://www.scilifelab.se/wp-content/uploads/2020/02/pills_600x200px.jpg
LOCATION:https://www.scilifelab.se/event/an-adaptable-drug-affinity-conjugate-adac-targeting-cd40-proof-of-concept-and-pharmaceutical-profiling/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20210608T140000
DTEND;TZID=Europe/Stockholm:20210609T120000
DTSTAMP:20260404T001250
CREATED:20210503T135818Z
LAST-MODIFIED:20210607T152505Z
UID:10000373-1623160800-1623240000@www.scilifelab.se
SUMMARY:CryoEM in Drug Discovery
DESCRIPTION:CryoEM has quickly become an essential tool in academic research\, with more than 1200 cryoEM structures deposited in the PDB in 2019. CryoEM is now also showing a significant impact on drug discovery in industry and academia. \n\n\n\nThis symposium\, co-arranged by the Drug Discovery and Development platform and the CryoEM unit at SciLifeLab\, highlights some of the recent advances in the field and familiarises the audience with the requirements\, opportunities\, and limitations of the technique. Speakers include leading scientists from both major pharma companies and academia. \n\n\n\nBy attending this symposium\, you learn what cryoEM can bring to your research\, what resources are available to Swedish researchers\, and how to get started. We welcome both Swedish and international participants.  \n\n\n\n \n\n\n\n \n\n\n\n\nregister here to receive zoom link\n\n\n\n\n\n\n\nSession 1\n\n\n\nAll time slots below are in UTC+2 / CEST Time zone [Stockholm\, Sweden]. \n\n\n\nJune 8th – Afternoon\n\n\n\n14:00Welcome wordsAnnika Jenmalm-Jensen\, Infrastructure Director\, SciLifeLab14:05Introduction to the cryo-EM Unit at SciLifelabMarta Carroni\, SciLifeLab/Stockholm University\, Sweden14:15From Concept to Reality: CryoEM as an Integral Part of Drug Discovery and Development Corey Strickland; Merck\, Kenilworth\, United States14:55CryoEM at AstraZenecaChris Phillips; Astra Zeneca\, UK15:25Short break15:30An integrated cryo-EM and AI based approach for new vaccine identificationIlaria Ferlenghi\, GSK\, UK16:00Cryo-EM structure of Helicobacter pylori urease with an inhibitor in the active site at 1.68 Å resolution Hartmut Luecke\, University of Oslo\, Norway16:30CryoEM in industry\, with an artisanal touchAlexis Rohou\, Genentech\, United States17:00Wrap upMarta Carroni\, SciLifeLab/Stockholm University\, Sweden\n\n\n\nSession 2\n\n\n\nAll time slots below are in UTC+2 / CEST Time zone [Stockholm\, Sweden]. \n\n\n\nJune 9th – Morning\n\n\n\n09:00Session 2 WelcomeMarta Carroni\, SciLifeLab/Stockholm University\, Sweden09:00Cryo-EM and crystal structure of the emerging cancer target PAICS incomplex with a low-nanomolar inhibitorJana Skerlova\, Stockholm University\, Sweden09:15Using Cryo-EM for GPCR Drug Discovery and Development Patrick M. Sexton\, Monash University\, Parkville\, Australia09:55Short break10:00Cryo-EM at NovartisMaryam Khoshouei\, Novartis\, Switzerland10:30CryoEM of SARM1 reveals a trigger of axon degenerationKatie Cunnea\, Evotec\, UK11:00Concluding RemarksMarta Carroni\, SciLifeLab/Stockholm University\, SwedenPer Arvidsson\, SciLifeLab/Karolinska Institutet\, SwedenAnders Olsson\, SciLifeLab/KTH Royal Institute of Technology\, Sweden\n\n\n\n\n\n\n\nScientific committee\n\n\n\nMarta Carroni\, Head of Cryo-EM unit\, SciLifeLabPer Arvidsson\, Director Drug Discovery and Development platform\, SciLifeLabAnders Olsson\, Head of Protein Expression and Characterization unit\, SciLifeLab
URL:https://www.scilifelab.se/event/cryoem-in-drug-discovery/
CATEGORIES:Event
LOCATION:https://www.scilifelab.se/event/cryoem-in-drug-discovery/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20210609T140000
DTEND;TZID=Europe/Stockholm:20210609T150000
DTSTAMP:20260404T001250
CREATED:20210519T132532Z
LAST-MODIFIED:20210519T133127Z
UID:10000389-1623247200-1623250800@www.scilifelab.se
SUMMARY:SciLifeLab AI Seminar Series: Arne Elofsson
DESCRIPTION:SciLifeLab Data Centre hosts a seminar series on the topic of applied AI in life science research. SciLifeLab AI Seminar Series combines scientific highlights from SciLifeLab-affiliated researchers and invited experts on the general topic of AI applications in Life Science. The SciLifeLab AI Seminar Series will be held virtually on Zoom and videos will be published openly after the seminars at the SciLifeLab YouTube channel. \n\n\n\nContact: Prof. Ola Spjuth\, AI coordinator\, SciLifeLab Data Center. \n\n\n\nUsing deep learning and coevolution to predict protein-protein interactions\n\n\n\nArne ElofssonStockholm University and Science for Life Laboratory \n\n\n\nAbstract \n\n\n\nIn the last decade de novo protein structure prediction accuracy for individual proteins\, by the use of co-evolution and deep learning harvesting the information from large multiple sequence alignments. In Casp14 it was shown that the best method can predict the structure for basically all proteins. This information can\, in principle\, also be used to extract information about protein-protein interaction\, but the success has so far been limited to a handful of proteins. However\, most of the earlier studies have not used the latest improvements achieved in contact-based predictions using deep learning to predict the distances between residue pairs. Here\, we first show that using one of the best residue-residue contact prediction methods (trRosetta) it is possible to simultaneously predict the structure of two proteins and their interaction for some proteins\, even when the structure of the monomers are not known. \n\n\n\nSecondly\, we apply this method to a standard dataset for protein-protein docking and find that the majority of the protein pairs are not docked correctly. By using alternative alignment methods to generate the multiple sequence alignments it is possible to accurately dock more proteins. The average performance is comparable to the use of alternative docking methods\, either template based or methods used by shape-complementarity\, although no structural information is needed for the individual proteins in a fold-and-dock pipeline. However\, the results are complementary as some methods work on some pairs and some on others.  \n\n\n\nWhen estimating differences between successful and unsuccessful fold-and-docked protein pairs.  We identify that the current method produces artefacts when there exists homology between the interacting proteins.  This bottleneck affects approximately one-third of the proteins pairs in our benchmark set. Further\, we find that one-third (?) of the proteins have too few sequences in the joint alignment. However\, for the remaining third (?) we can not find a good explanation why the docking was not successful. \n\n\n\nFinally\, we introduce a novel scoring function\, PconsDock\, that can be used to evaluate the quality of a protein-protein pair. This simple scoring scheme is very accurate as it can separate 98% of the correct and incorrect proteins.  \n\n\n\nRegister here
URL:https://www.scilifelab.se/event/scilifelab-ai-seminar-series-arne-elofsson/
CATEGORIES:Event
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20210610T130000
DTEND;TZID=Europe/Stockholm:20210610T140000
DTSTAMP:20260404T001250
CREATED:20210503T144024Z
LAST-MODIFIED:20210524T135338Z
UID:10000379-1623330000-1623333600@www.scilifelab.se
SUMMARY:Campus Solna Seminar Series: Gabriele Girelli and Ximena Lopez
DESCRIPTION:Introducing the new Campus Solna Seminar Series – a new initiative to promote the fantastic science ongoing at Campus Solna and hopefully forge more internal communication and collaboration between the alpha and gamma buildings. The format will be 2 short 15 min talks (1 speaker from alpha and 1 from gamma)\, with an additional 5 min of questions. Presentation of ongoing (unpublished) projects is strongly encouraged. \n\n\n\nThe seminars are held Thursdays 13:00-13:50 and following current regulations\, they will be broadcast via zoom. \n\n\n\n\n\n\nGabriele Girelli\n\n\n\nGPSeq – controlled diffusion to study radiality \n\n\n\nMagda Bienko – Alpha 4 \n\n\n\n\n\nXimena Lopez\n\n\n\nChemoenzymatic degradation of PET plastic \n\n\n\nPer-Olof Syrén – Gamma 5 \n\n\n\n\n\n\nRegister to receive the zoom-link. The same zoom link applies for all Campus Solna Seminar Series\, i.e. only one registration is necessary. \n\n\nPlease select a valid form
URL:https://www.scilifelab.se/event/campus-solna-seminar-series-gabriele-girelli-and-ximena-lopez/
CATEGORIES:Community
ORGANIZER;CN="SciLifeLab Solna PhD & Postdoc Council":MAILTO:phd-council@scilifelab.se
LOCATION:
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20210611T130000
DTEND;TZID=Europe/Stockholm:20210611T160000
DTSTAMP:20260404T001250
CREATED:20210503T135955Z
LAST-MODIFIED:20210609T083612Z
UID:10000374-1623416400-1623427200@www.scilifelab.se
SUMMARY:DDLS and WASP join forces for research within a data-driven future
DESCRIPTION:Welcome to the official launch of the DDLS-WASP collaboration! \n\n\n\nThe two largest research programs in Sweden\, the Wallenberg AI\, Autonomous Systems and Software Program (WASP) and the SciLifeLab and Wallenberg National Program for Data-Driven Life Science (DDLS)\, will team up in a new collaborative effort\, with the ultimate goal of solving groundbreaking research questions and to create synergies across disciplines. \n\n\n\nThis Zoom meeting will combine inspirational talks and discuss possible ways to initiate formations of strong collaborations that can bridge  the gap between the scientific disciplines. We welcome WASP researchers and life scientists to take part in the webinar and to actively engage in new alliances.  \n\n\n\nThe first part of the meeting will be recorded and published on WASP and SciLifeLab YouTube channels.  \n\n\n\n\n\n\n\nRegistration\n\n\n\n\n\n\n\n\nMatchmaking: submit an abstract! \n\n\n\nPrepare for the joint call! To find potential collaborators\, common topics\, exchange ideas and opportunities\, and raise awareness of competencies on each side\, we invite you to submit an abstract. The Abstracts will be published in a PDF\, updated every Monday (except during July) until the Call closes.  \n\n\n\nMatchmaking: Submit an Abstract\n\n\n\n\n\n\n\n\nProgram\n\n\n\nProgram WASP-DDLS June 11 (PDF)Download\n\n\n\n\n\n\n\nSession 1Hosts: Danica Kragic and Erik Lindahl13:00Welcome wordsSiv Andersson\, KAW\, Sara Mazur\, KAW\, Chair of WASP board\, Carl-Henrik Heldin\, Chair of SciLifeLab board13:15WASP\, Introducing WASP and bringing awareness of WASP to the DDLS communityAnders Ynnerman \, Director of WASP13:35DDLS\, Introducing DDLS and bringing awareness of DDLS to the WASP communityOlli Kallioniemi\, Director of SciLifeLab and DDLS13:55Joined forces for an increasingly data-driven futureInformation about our new collaboration and purpose of bridging WASP and DDLS research programs. Information about joint call.Danica Kragic\, Professor of Computer Science\, KTH\, Erik Lindahl\, Professor of Biophysics\, Stockholm University14:15Q&A session about the joint callModerators Danica Kragic and Erik LindahlPanel Anders Ynnerman\, Olli Kallioniemi and the joint WASP-DDLS working group14:35Short breakSession 2Host: Carolina Wählby14:45Inspirational TalksModerator Carolina Wählby\, Professor of Quantitative Microscopy\, Uppsala university Deep learning in drug discovery\, a WASP/AstraZeneca/KTH collaboration (8+2)Kevin Smith\, Associate Professor\, Division of Computational Science and Technology\, KTHFinding connections: how deep learning can help with COVID-19 and other major health challenges (8+2)Sonja Aits\, Associate Senior Lecturer\, Lund UniversityThe automation of Biology (16+4)Ross King\, Wallenberg Chair in AI\, Professor of Machine Intelligence\, Chalmers University of Technology15:25SummaryAnders Ynnerman\, Olli Kallioniemi15:30Informal breakout room discussions16:00End of day
URL:https://www.scilifelab.se/event/ddls-and-wasp-join-forces-for-research-within-a-data-driven-future/
CATEGORIES:Event
ATTACH;FMTTYPE=image/jpeg:https://www.scilifelab.se/wp-content/uploads/2021/04/DDLS_WASP_WP.jpg
LOCATION:https://www.scilifelab.se/event/ddls-and-wasp-join-forces-for-research-within-a-data-driven-future/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20210614T080000
DTEND;TZID=Europe/Stockholm:20210616T170000
DTSTAMP:20260404T001250
CREATED:20210503T143343Z
LAST-MODIFIED:20210608T152652Z
UID:10000377-1623657600-1623862800@www.scilifelab.se
SUMMARY:Campus Solna Science talks 2021
DESCRIPTION:SciLifeLab Campus Solna symposium is designed to inform the community about recent work\, provide an opportunity for scientists to present ongoing research\, and introduce new fellows.  \n\n\n\nTo create an open environment that encourages the unrestrained sharing of ongoing research and unpublished work\, the taking of screen shots\, video or audio recording is not allowed during the presentations. Of course\, taking written notes is fine. \n\n\n\nFor details please email science.talks@scilifelab.se \n\n\n\nRegister to Science Talks\n\n\n\n\n\n\n\nProgram\n\n\n\nProgram Science Talks 2021Download\n\n\n\nMonday\, June 14\n\n\n\n09:00Opening note – Welcome to Science Talks\, Per Ljungdahl\, SciLifeLab Campus Solna DirectorBioimagingChair: Per Ljungdahl09:05Ilaria Testa (KTH)\, A new observable window into living cells at high spatio-temporal resolution09:15Taras Sych (KI)\, Biophysical characterization of nano-sized physiological lipid particles with fluorescence flucutuometry09:25Linnea Nordahl (KTH)\, Interactions within the Na/K-ATPase09:35Hans Blom (KTH)\, Diagnosis of kidney diseases with all scale optical microscopy09:45Q&A with speakers10:00BreakCellular and Molecular BiologyChair: Marcel Tarbier10:10Lucie Delemotte (KTH)\, Elucidation of G protein-coupled receptor activation via data-driven modeling10:20Alexey Amunts (SU)\, Structural studies of bioenergetic complexes10:30Fitz Gerald S. Silao (SU)\, Proline assimilation is intrinsic to the opportunistic ecophagy of Candida albicans-infected hosts10:40Paul Hudson (KTH)\, Engineering the microbial Calvin cycle for bio-sustainability applications10:50Q&A with speakers11:05BreakCellular and Molecular BiologyChair: Vicent Pelechano11:15Eleni Gelali (KI)\, Deconwolf: a free deconvolution software that can facilitate imaging-based spatially resolved omics11:25Lukas Käll (KTH)\, Survival Analysis Based on Cancers’ Pathway Activity11:35Maurice Grube (KI)\, Small molecule activation of OGG1 increases base excision repair by gaining a new enzymatic function11:45Banushree Kumar (KI)\, Function of PRC2 in naïve and primed human pluripotency11:55Q&A with speakers12:10End of day\n\n\n\n\n\n\n\n\n\nTuesday\, June 15\n\n\n\nNucleic Acids and Multi-omicsChair: Alexey Amunts09:00Opening note09:05Stefania Giacomello (KTH)\, Understanding the impact of spaceflight on mouse brain and heart by using spatial multiomics methods09:15Marc Friedländer (SU)\, Ancient RNA – possibilities and challenges09:25Christian Sommerauer (KI)\, Are female sex hormones the key to preventing liver diseases?09:35Claudia Kutter (KI)\, High resolution RAPseq identifies functional propensities of RNA binding proteins in diseases and species evolution09:45Q&A with speakers10:00Break10:10Paula Pierozan (SU)\, re common per- and polyfluoroalkyl substances linked to breast cancer? -mechanistic studies by high-content screening and DNA methylation analysis10:20Kristoffer Sahlin (SU)\, Strobemers: an alternative to k-mers for sequence comparison\, clustering\, and alignment10:30Alisa Alekseenko (KI)\, OPUS-seq: One Pot Double Stranded UMI Sequencing10:40Lilit Nersisyan (KI)\, RNA degradation analysis reveals ribosome dynamics in complex microbiome samples10:50Q&A with speakers11:05BreakNucleic Acids and Multi-omicsChair: Vaishnovi Sekar11:15Cecilia Williams (KTH)\, Colorectal cancer development: sex differences and impact of estrogen11:25Erik Sonnhammer (SU)\, Network-based pathway analysis and drug repurposing\, with application to COVID-1911:35Jean Hausser (KI)\, Quantitative principles of tumor micro-architecture11:45Boyang Guo (KTH)\, The perfect fit: enzyme and substrate conformations in plastic degradation11:55Q&A with speakers12:10End of day\n\n\n\n\n\n\n\n\n\nWednesday\, June 16\n\n\n\nEpidemiology and DiagnosticsChair: Lucie Rodriguez09:00Opening note09:05Petter Brodin (KI)\, Human systems immunology09:15Ludvig Larsson (KTH)\, Molecular characterization of the mouse intestine09:25Jochen Schwenk (KTH)\, Decoding clinical heterogenity with the circulating proteome09:35Tea Dodig-Crnkovic (KTH)\, Multiplexed analysis of the GPCR-RAMP interactome09:45Q&A with speakers10:00BreakEpidemiology and DiagnosticsChair: Aditi Shenoy10:10Peter Nilsson (KTH)\, Development of a multiplex COVID-19 serology10:20Mats Nilsson (SU)\, The single sell- and spatial biology platform10:30Isabelle Leo (KI)\, Using proteomics to guide translational study of biology and biomarkers in childhood ALL10:40Aman Russom (KTH)\, Life at the micro- and nanoscale: microfluidics for clinical applications10:50Q&A with speakers11:05BreakNew RecruitmentsChair: Disa Hammarlöf11:15Iskra Pollak Dorocic (SU)\, Deciphering the molecular\, anatomical and functional diversity of neuromodulatory neurons11:25Anniina Vihervaara (KTH)\, Coordinating transcription at physically-linked genes and enhancers in stress and development11:35Saeed Shoaie (KTH)\, Global and temporal state of human microbiome11:45Tuuli Lappalainen (KTH)\, Functional variation in the human genome: lessons from the transcriptome11:55Q&A with speakers12:10Science communication AwardsOlli Kallioniemi\, Director SciLifeLab12:15Closing noteOlli Kallioniemi\, Director SciLifeLab
URL:https://www.scilifelab.se/event/campus-solna-science-talks-2021/
CATEGORIES:Community
LOCATION:https://www.scilifelab.se/event/campus-solna-science-talks-2021/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20210614T080000
DTEND;TZID=Europe/Stockholm:20210624T170000
DTSTAMP:20260404T001250
CREATED:20210503T140254Z
LAST-MODIFIED:20210503T141941Z
UID:10000375-1623657600-1624554000@www.scilifelab.se
SUMMARY:RaukR\, Advanced R for Bioinformatics\, Summer course
DESCRIPTION:International course. The course is open for researchers at university or in industry such as PhD students\, postdocs\, group leaders\, core unit staff and analysts.Apply hereCourse website \n\n\n\ncourse website\n\n\n\nThe course is organised by NBIS \n\n\n\nResponsible teachers: Marcin Kierczak\, Sebastian DiLorenzoContact: RaukR@NBIS.se \n\n\n\nImportant dates\n\n\n\nApplication deadline: Friday\, 23.04.2021\, 24:00 GMTNotification of acceptance/decline: Friday\, 30.04.2021 \n\n\n\nCourse fee\n\n\n\nAcademic: No fee this year. However\, if you register and will be admitted but you will not attend the event without a valid reason\, you will be charged a no-show fee (3000 SEK).Participants from outside of academia should contact us for a fee quote. \n\n\n\nCourse description\n\n\n\nJoin us online this June to improve your R skills and have a nice time!In Life Science and Bioinformatics\, R is increasingly being used to transform and analyse data\, perform statistical analysis and produce publication-ready visualisations. This Summer course will focus on advanced R functionality\, to increase the participants skillset and understanding of what is possible to do today. \n\n\n\nBig part of RaukR experience was coding and exchanging knowledge in a unique environment provided by Campus Visby in Gotland. Sadly\, due to COVID-19 outbreak\, RaukR 2020 did not happen. This year\, we still have to obey a number of restrictions and guidelines due to the outbreak. While we still cannot gather in Visby\, we decided to go online and we hope this year we will also learn a lot and have fun coding together! We wish you all the best. See you online! Stay safe and healthy! \n\n\n\nYou are very welcome to apply or see the homepage for more information. Please\, help us spread the word to interested participants! \n\n\n\nGuest speaker\n\n\n\nMax Kuhn (software engineer at RStudio) \n\n\n\nCourse content\n\n\n\nreproducible research in R (rmarkdown\, knitr)\,collaborative work using git and GitHub\, CD/CI\,R code style guidelines\,parallelization and vectorization in R\,writing own functions – best practices\,understanding and using the system of R classes: S3\, S4\, R6 and RC\,anatomy of an R package: writing your own package from scratch\,code debugging\, profiling and optimization\,tidy data flow with tidyverse\,efficient use of magrittr pipes\,using the language of graphics\, ggplot2\,developing simple web applications using shiny\,efficient modelingthe second week will be devoted to collaborative project workthe last day\, all groups will present their project work\n\n\n\nEntry requirements\n\n\n\nThe course is aimed at both Ph.D. students and researchers within Life Sciences who are already using R for basic bioinformatics analyses and who would like to start using R at a more advanced level. In order for you and other participants to benefit the most\, you should consider yourself eligible if you are comfortable with reading and transforming data\, installing and using third-party packages and plotting using standard R graphics. \n\n\n\nWe offer places for participants from all over the world\, but there is a number of places reserved for participants from Sweden. \n\n\n\nSelection criteria\n\n\n\nThis year\, the school can accommodate ~30 participants. Selection criteria include correct entry requirements\, motivation to attend the course as well as gender and geographical balance. This year\, we will also give priority to students who have already been admitted to RaukR 2020 (which had been cancelled).
URL:https://www.scilifelab.se/event/raukr-advanced-r-for-bioinformatics-summer-course/
CATEGORIES:Course
ORGANIZER;CN="NBIS - National Bioinformatics Infrastructure Sweden":MAILTO:education@nbis.se
LOCATION:https://www.scilifelab.se/event/raukr-advanced-r-for-bioinformatics-summer-course/
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BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20210617T130000
DTEND;TZID=Europe/Stockholm:20210617T140000
DTSTAMP:20260404T001250
CREATED:20210503T143813Z
LAST-MODIFIED:20210601T093048Z
UID:10000378-1623934800-1623938400@www.scilifelab.se
SUMMARY:Campus Solna Seminar Series: Woonghee Kim and Markus Hilscher
DESCRIPTION:Introducing the new Campus Solna Seminar Series – a new initiative to promote the fantastic science ongoing at Campus Solna and hopefully forge more internal communication and collaboration between the alpha and gamma buildings. The format will be 2 short 15 min talks (1 speaker from alpha and 1 from gamma)\, with an additional 5 min of questions. Presentation of ongoing (unpublished) projects is strongly encouraged. \n\n\n\nThe seminars are held Thursdays 13:00-13:50 and following current regulations\, they will be broadcast via zoom. \n\n\n\n\n\n\nWoonghee Kim\n\n\n\nDrug discovery: Disease modeling and assessment of new small molecules for Non Alcoholic Fatty Liver Disease (NAFLD) \n\n\n\nAdil Mardinoglu\, Alpha 6 \n\n\n\n\n\nMarkus Hilscher\n\n\n\nBeyond a cell atlas – applications of in situ sequencing to models of disease \n\n\n\nMats Nilsson\, Gamma 4 \n\n\n\n\n\n\nRegister to receive the zoom-link. The same zoom link applies for all Campus Solna Seminar Series\, i.e. only one registration is necessary. \n\n\nPlease select a valid form
URL:https://www.scilifelab.se/event/campus-solna-seminar-series-woonghee-kim-and-markus-hilscher/
CATEGORIES:Community
ORGANIZER;CN="SciLifeLab Solna PhD & Postdoc Council":MAILTO:phd-council@scilifelab.se
LOCATION:
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BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20210623T130000
DTEND;TZID=Europe/Stockholm:20210623T160000
DTSTAMP:20260404T001250
CREATED:20210601T073659Z
LAST-MODIFIED:20210601T075456Z
UID:10000394-1624453200-1624464000@www.scilifelab.se
SUMMARY:SciLifeLab Workshop on Federated Machine Learning
DESCRIPTION:Location: Online via Zoom\n\n\n\nProgram:\n\n\n\n13.00 – 13.45  Presentation: Introduction to Federated Machine Learning \n\n\n\n14.00 – 16.00  Hands-on workshop: How to set up\, run and deploy a federated learning project using the FEDn open source solution \n\n\n\nNote that it is possible to attend the first presentation only\, or both presentation and workshop. \n\n\n\nWhat is Federated Machine Learning?\n\n\n\n\nFederated learning enables several organizations / groups to collaborate on machine learning models without needing to directly share sensitive or confidential data with each other.It is a distributed machine learning approach which enables training on decentralised data. A server coordinates a network of nodes\, each of which has local\, private training data. These nodes contribute to the construction of a global model by training on local data\, and the server combines non-sensitive node model contributions into the global model. \n\n\n\nFor a short (10min ) introduction see: https://www.youtube.com/watch?v=jbLHRtGWPL8 \n\n\n\n\nWho should attend?\n\n\n\n1.Researchers who are interested in learning more about FedML \n\n\n\n2.Researchers who are interested in testing FedML hands-on in the FEDn solution \n\n\n\nAbout the organizers\n\n\n\nScaleout consists of a team of data scientists\, machine learning engineers\, software engineers\, and entrepreneurs with experience from both industry and academic research in AI and applied machine learning\, cloud and fog computing\, and scientific computing from Uppsala University. We’re working on a platform for end-to-end privacy-preserving machine learning with a focus on helping organisations put advanced machine learning and DevOps technologies into production. \n\n\n\nRegistration\n\n\n\nThe presentation and the workshop is free of charge but requires registration. The number of seats for the hands-on part of the workshop is limited to 20 people so only register for the workshop if you are interested in actively participating in the tutorial. \n\n\n\nContact: Prof. Ola Spjuth\, AI coordinator\, SciLifeLab Data Centre. \n\n\n\nRegister here
URL:https://www.scilifelab.se/event/fedml/
LOCATION:Online event via Zoom
CATEGORIES:Event
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