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DTSTART;TZID=Europe/Stockholm:20240603T151500
DTEND;TZID=Europe/Stockholm:20240603T161500
DTSTAMP:20260407T133456
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SUMMARY:[The Svedberg seminar] Combining artificial intelligence approaches and cellular screens to define functional regulatory variation in mammalian genomes
DESCRIPTION:James Prendergast \n\n\n\nProfessorRoslin Institute\, University of Edinburgh- UK \n\n\n\n \n\n\n\n\n\n\n\nBio\n\n\n\nJames Prendergast is professor of bioinformatics at the Roslin Institute in Edinburgh. His academic journey began with a focus on the genetics of colorectal cancer during the early days of genome-wide association studies\, leading to a PhD in Bioinformatics and Statistical Genetics from the University of Edinburgh in 2007. \n\n\n\nAfter completing his PhD\, James held post-doctoral positions at the European Bioinformatics Institute and University College Dublin\, before joining the Human Genetics Unit at the University of Edinburgh. In 2013\, he transitioned to livestock research\, first joining the Roslin Institute on a career-track fellowship. \n\n\n\nThrough his career\, James has been part of several international consortia\, including the FAANG BovReg project\, Bridget\, FANTOM\, and the Bovine Pangenome Consortium. These collaborations have allowed him to continue to work across both human and livestock genetics research. \n\n\n\n \n\n\n\nCombining artificial intelligence approaches and cellular screens to define functional regulatory variation in mammalian genomes\n\n\n\n \n\n\n\nDespite significant progress\, the exact genetic variants that influence crucial mammalian traits and phenotypes often remain unknown. This uncertainty presents a significant challenge to the enhancement of livestock health and production through cutting-edge genomic approaches like genome editing. While predicting functional coding variants is comparatively straightforward\, it is suggested that regulatory variants are the primary drivers of phenotypic differences between individuals. In this talk\, I will delve into our efforts to bridge this knowledge gap by integrating novel cellular screen datasets and AI workflows to predict functional regulatory variants in mammalian genomes. This includes the pioneering application of the Survey of Regulatory Elements (SuRE) approach to cattle\, where we have scrutinized the regulatory impact of tens of millions of cattle variants\, while effectively eliminating the confounding effect of linkage disequilibrium that hampers other methodologies. I will demonstrate how these strategies can not only effectively prioritize regulatory variants in both humans and cattle\, but also identify those variants associated with significant phenotypes in each species. \n\n\n\n \n\n\n\n\n\n\n\n Host: Gabriella Lindgren\, SLU and Jennifer Meadows\, UU
URL:https://www.scilifelab.se/event/the-svedberg-seminar-james-prendergast/
LOCATION:BMC Room C8:301\, Husargatan 3\, Uppsala\, Sweden
CATEGORIES:Event
ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2022/02/Picture1-The-Svedberg.png
ORGANIZER;CN="The Svedberg Seminar Series":MAILTO:thesvedberg@scilifelab.uu.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20240610T080000
DTEND;TZID=Europe/Stockholm:20240620T170000
DTSTAMP:20260407T133456
CREATED:20240301T094124Z
LAST-MODIFIED:20240425T075210Z
UID:10001181-1718006400-1718902800@www.scilifelab.se
SUMMARY:RaukR\, Advanced R for Bioinformatics workshop
DESCRIPTION:Join us this June in beautiful and historic Visby to improve your R skills and have a nice time! \n\n\n\nIn Life Science and Bioinformatics\, R is increasingly being used to transform and analyse data\, perform statistical analysis and produce publication-ready visualisations. This workshop will focus on advanced R functionality\, to increase the participants skillset and understanding of what is possible to do today. \n\n\n\nYou are very welcome to apply or see the homepage for more information. Please\, help us spread the word to interested participants! \n\n\n\nLink to registration\n\n\n\nLink to course website\n\n\n\n\nReproducible research in R (Quarto\, Rmarkdown\, Renv)\n\n\n\nCollaborative work in R using Git and GitHub\n\n\n\nR code style guide & best practices\n\n\n\nCode debugging\, optimization and profiling\n\n\n\nParallelization and vectorization in R\n\n\n\nCrafting your own functions\n\n\n\nObject oriented programming and R classes: S3\, S4\, R6 and RC\n\n\n\nAnatomy of an R package: Creating your own package from scratch\n\n\n\nTidy data flow using tidyverse\n\n\n\nUsing the language of graphics: ggplot2\n\n\n\nDeveloping web applications using Shiny\n\n\n\nR and Python integration using reticulate\n\n\n\nTeam project work – developing data analyses workflow in R using acquired skills\n\n\n\n\nNote that topics covered may be subject to change. \n\n\n\nThe course is open for researchers at university or in industry such as PhD students\, postdocs\, group leaders\, core facility staff and analysts. \n\n\n\nCourse fee\n\n\n\nA course fee* of 8000 SEK will be invoiced to accepted participants. The fee includes \n\n\n\n\nParticipation in lectures and workshops\n\n\n\nMingle reception with snacks and drinks\n\n\n\nDaily breakfast/coffee\, lunch and afternoon coffee during the workshop\n\n\n\nOne official course dinner\n\n\n\nSurprise social activities\n\n\n\n\n*Please note that NBIS cannot invoice individuals \n\n\n\nImportant dates and information\n\n\n\nApplication opens: 2024-02-22 \n\n\n\nApplication closes: 2024-04-14 \n\n\n\nFor late registrations\, contact the course leaders directly! \n\n\n\nConfirmation to accepted students: 2024-04-17 \n\n\n\nCourse Leader and teachers:  \n\n\n\nSebastian DiLorenzo\, CL \n\n\n\nMarcin Kierczak\, CL \n\n\n\nRoy Francis \n\n\n\nJenny Bryan\, guest lecturer\, Posit \n\n\n\nHenrik Bengtsson\, guest lecturer\, University of California \n\n\n\nIn case you miss information on any of the above dates\, please contact: Course leaders at raukr@nbis.se \n\n\n\nLearning Outcomes\n\n\n\nUpon completion of this course\, you will be able to: \n\n\n\n\nWork collaboratively and reproducibly in R\n\n\n\nOptimize R code\n\n\n\nUnderstand R code to a greater extent\n\n\n\nCreate better visualizations\n\n\n\nAnd more!\n\n\n\n\nEntry requirements\n\n\n\nThe course is aimed at both Ph.D. students and researchers within Life Sciences who are already using R for basic bioinformatics analyses and who would like to start using R at a more advanced level. In order for you and other participants to benefit the most\, you should consider yourself eligible if you are comfortable with reading and transforming data\, installing and using third-party packages and plotting using standard R graphics. \n\n\n\nWe offer places for participants from all over the world\, but there are a number of places reserved for participants from Sweden.Due to limited space the course can accommodate approximately 45 participants. If we receive more applications\, participants will be selected based on selection criteria\, including (but not limited to) correct entry requirements\, motivation to attend the course\, as well as gender and geographical balance.
URL:https://www.scilifelab.se/event/raukr-advanced-r-for-bioinformatics-workshop-3/
CATEGORIES:Course
ORGANIZER;CN="NBIS - National Bioinformatics Infrastructure Sweden":MAILTO:education@nbis.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20240613T120000
DTEND;TZID=Europe/Stockholm:20240613T130000
DTSTAMP:20260407T133456
CREATED:20240102T100507Z
LAST-MODIFIED:20240604T073315Z
UID:10001096-1718280000-1718283600@www.scilifelab.se
SUMMARY:Campus Solna Seminar Series: Fatima Liliana Monteiro & Jakub Mlost
DESCRIPTION:Welcome to join the Campus Solna Seminar Series – an  initiative to promote the fantastic science ongoing at Campus Solna and hopefully forge more internal communication and collaboration between within Campus Solna. The format consists of two 15 min talks (One speaker from the Alpha-building and one from the Gamma-building respectively)\, with an additional 5 min of questions. Presentation of ongoing (unpublished) projects is strongly encouraged. \n\n\n\nThe seminars are held Thursdays 12:00-13:00. You can bring your lunch to the seminar. \n\n\n\nThis week:\n\n\n\n\n\n\nFatima Liliana Monteiro\n\n\n\nCecilia Williams – alpha 2 \n\n\n\nUnveiling Antibody Pitfalls in Estrogen Receptor Research \n\n\n\n\n\nJakub Mlost\n\n\n\nIskra Pollak Dorocic – gamma 5 \n\n\n\nProjection Specific Serotonergic Pathways: Insights from Behavioral Tests and Neural Activity Mapping \n\n\n\n\n\n\nThis seminar series is organized by the PhD & Postdoc Council. For more information about the Council and other events check our page.
URL:https://www.scilifelab.se/event/campus-solna-seminar-series-linnea-lindquist-anna-schupe/
LOCATION:Air&Fire\, SciLifeLab Stockholm\, Tomtebodavägen 23A\, Solna\, Sweden
CATEGORIES:Community
ATTACH;FMTTYPE=image/jpeg:https://www.scilifelab.se/wp-content/uploads/2022/12/IMG_4110-scaled.jpg
ORGANIZER;CN="SciLifeLab Solna PhD & Postdoc Council":MAILTO:phd-council@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20240616T080000
DTEND;TZID=Europe/Stockholm:20240620T170000
DTSTAMP:20260407T133456
CREATED:20240219T110329Z
LAST-MODIFIED:20240219T110353Z
UID:10001164-1718524800-1718902800@www.scilifelab.se
SUMMARY:Advanced course in Metabolic Engineering & Systems Biology (MESB)
DESCRIPTION:The advanced course in Metabolic Engineering & Systems Biology (MESB) is organized by the Systems and Synthetic Biology division at Chalmers University of Technology\, and is intended for PhD students\, postdocs\, academic and industrial researchers that are interested in computational aspects of metabolic engineering. \n\n\n\nAim & content\n\n\n\nThe aim of the course is to provide participants with a strong primer of various (computational) aspects of metabolic engineering. In particular\, the course covers the following topics: \n\n\n\n\nConstraint-based genome-scale modelling\n\n\n\nEnzyme-constrained modelling\n\n\n\nFermentation technologies\n\n\n\nProteomics technologies\n\n\n\nRNAseq data generation and analysis\n\n\n\nIntegrative gene-expression data analysis\n\n\n\n\nA central question in all the activities is How can I use this in my metabolic engineering project? \n\n\n\nTeaching format\n\n\n\nThe course is intensive and will require precourse studying of material that will be provided closer to the start date. During the course\, teaching will be via lectures\, while also significant time (most afternoons) is allocated for hands-on computer exercises. \n\n\n\nLecturers\n\n\n\nEduard KerkhovenJosé Luis Martínez RuizPetri-Jaan LahtveeVerena SiewersYun ChenCHALMERS\, SwedenDTU\, DenmarkTalTech\, EstoniaCHALMERS\, SwedenCHALMERS\, Sweden
URL:https://www.scilifelab.se/event/advanced-course-in-metabolic-engineering-systems-biology-mesb/
CATEGORIES:Course
ORGANIZER;CN="SciLifeLab Gothenburg":MAILTO:gothenburg@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20240617T130000
DTEND;TZID=Europe/Stockholm:20240617T140000
DTSTAMP:20260407T133456
CREATED:20240508T124016Z
LAST-MODIFIED:20240516T084026Z
UID:10001258-1718629200-1718632800@www.scilifelab.se
SUMMARY:How protein degraders work: Molecular mechanism and drug design
DESCRIPTION:Alessio Ciulli \n\n\n\n\n\n\n\nProfessor of Chemical Structural Biology \n\n\n\nFounder and Director\, Centre for Targeted Protein Degradation \n\n\n\nSchool of Life Sciences\, University of Dundee \n\n\n\nAbstract\n\n\n\nProtein degraders (also known as PROTACs and molecular glues) are a new class of small molecule tools and drugs that trigger the rapid depletion of a target protein inside the cell. Degraders work via forming a ternary complex\, bridging a target protein to a ubiquitin E3 ligase. This allows the E3 ligase to label the target protein with ubiquitin molecules\, leading to the protein being recognized and degraded by the proteasome. Whereas conventional drugs only inhibit disease-causing proteins by binding and locking up their most important functional parts for the duration of the drug’s action\, degraders can bind at any positions and cause the protein rapid and long-lasting destruction. This lecture will recount some of our fundamental discoveries and insights that have helped to advance understanding and illuminate the molecular mechanism of how degraders work. It will illustrate how such fundamental principles have been applied to design high-quality degraders against challenging drug targets\, and will highlight some of the latest progress from the laboratory. \n\n\n\nBiography\n\n\n\nAlessio Ciulli studied chemistry in Florence\, Italy\, and obtained his PhD from the University of Cambridge\, UK\, in 2006. After postdoctoral research in Cambridge and a brief visit at Yale University in the USA\, he returned to Cambridge in 2009 to start his independent laboratory. In 2013\, he moved to the University of Dundee\, UK\, where he was promoted to full professor in 2016. He has received numerous prizes and awards for his discoveries\, most recently the 2022 Prous Institute – Overton and Meyer Award for New Technologies in Drug Discovery from the European Federation of Medicinal Chemistry (EFMC). In 2023 he was elected Fellow of the Royal Society of Edinburgh. He is the scientific founder of Amphista therapeutics\, a targeted protein degradation company spin out of his laboratory\, and the founder and director of the University of Dundee’s new Centre for Targeted Protein Degradation which opened in January 2023. The Ciulli Laboratory focuses on chemical biology and structural biology to develop small molecules inducing targeted protein degradation and modulating protein-protein interactions and translates their fundamental research via collaboration partnership with the biopharma industry and by creation of spin-out companies.
URL:https://www.scilifelab.se/event/how-protein-degraders-work-molecular-mechanism-and-drug-design/
LOCATION:Petrén Hall\, Nobels väg 12B\, Solna\, 17121\, Sweden
CATEGORIES:Event
ORGANIZER;CN="SciLifeLab Event":MAILTO:events@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20240617T140000
DTEND;TZID=Europe/Stockholm:20240617T190000
DTSTAMP:20260407T133456
CREATED:20240426T121303Z
LAST-MODIFIED:20240614T210606Z
UID:10001238-1718632800-1718650800@www.scilifelab.se
SUMMARY:Open House at Campus Solna
DESCRIPTION:Welcome to SciLifeLab Campus Solna!\n\n\n\nTake the opportunity to tour some of the SciLifeLab infrastructures hosted at Campus Solna organized by: \n\n\n\n\nChemical Biology & Genome Engineering and Drug Discovery & Development platforms\n\n\n\nGenomics (NGI)\, Cell & Molecular Imaging and Integrated Structural Biology platforms\n\n\n\nSpatial Biology platform\n\n\n\nClinical Genomics and Clinical Proteomics & Immunology platforms\n\n\n\nMetabolomics platform – Exposomics\n\n\n\n\nThis open house is open to everyone interested in learning more about the SciLifeLab Research infrastructures available to life science experts all over Sweden. \n\n\n\nLast day to register is June 11th \n\n\n\nRegister Here\n\n\n\nProgram\n \n\n\n\n13.30Registration and Coffee14.00Welcome to SciLifeLab!Instructions\, information and introductions to tour sessionsPer Ljungdahl\, Campus Solna Director14.15Tour Session #15 different tours available\, presented below15.00Tour Session #25 different tours available\, presented below15.45Tour Session #35 different tours available\, presented below16.30Poster sessionMeet all the SciLifeLab Platforms and research infrastructures17.00Mingle with light food and pub\n\n\n\n\nTours\nEach tour is repeated 3 times. Participants can choose 1 of 5 tours for each occasion. Participation in 3 different tours is possible \n\n\n\n\nAcademic drug discovery projects and services – small molecule and genetic perturbations on biological systemsorganised by  Chemical Biology & Genome Engineering and Drug Discovery & Development platforms\n\n\n\nCryoEM / ALM / NGI – Intricate genomes and super resolution imaging with electrons and photonsorganised by Genomics (NGI)\, Cell & Molecular Imaging and Integrated Structural Biology platforms\n\n\n\nSpatial transcriptomics using in situ sequencingorganised by Spatial Biology platform\n\n\n\nGenomic-based analyses using next generation sequencing and protein analyses using cutting edge immunoassay technologiesorganised by Clinical Genomics and Clinical Proteomics & Immunology platforms\n\n\n\nExposomics: National infrastructure to study chemical exposures in human and the environmentorganised by Metabolomics platform\n\n\n\n\n\n\n\n\n\nOrganizers\n\n\n\nMarta CarroniAnna-Lena GustafssonAnna GellerbringKatarina TiklovaStefano PapazianPer LjungdahlIsolde Palombo
URL:https://www.scilifelab.se/event/open-house-at-campus-solna/
LOCATION:SciLifeLab Campus Solna\, Tomtebodavägen 23 A\, Solna\, Sweden
CATEGORIES:Event
ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2024/04/Campus-Solna-Open-House.png
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20240618T080000
DTEND;TZID=Europe/Stockholm:20240619T170000
DTSTAMP:20260407T133456
CREATED:20231020T081018Z
LAST-MODIFIED:20240618T044504Z
UID:10001007-1718697600-1718816400@www.scilifelab.se
SUMMARY:Facility Forum 2024
DESCRIPTION:Dear SciLifeLab Infrastructure Team\, \n\n\n\nWe have finally arrived! It’s time for the SciLifeLab Facility Forum 2024. We look forward to your participation in this engaging and informative experience on June 18-19\, 2024\, at the Clarion Sign Hotel in central Stockholm.This year\, the event will bring together 442 participants\, continuing the growth from the first Facility Forum in Uppsala in 2017 with 253 participants\, 338 in Djurönäset in 2019\, and 376 for the last meeting in Djurönäset in 2022. The primary objectives of the meeting are to promote cross-facility collaborations\, increase community feeling among platform and facility personnel\, discuss specific infrastructure issues\, foster competence development\, and provide ample time for discussion and exchange.One highlight of the event will be a session with the current and new SciLifeLab directors\, where they will share and discuss their visions for the future of Life Science and SciLifeLab. Additionally\, the program includes various sessions and workshops aimed at enhancing collaboration and professional growth.We are excited to have you join us! Below\, you can find all the important information you need to know to make your participation easier. \n\n\n\nAnnika Jenmalm Jensen\, Infrastructure Director SciLifeLabLars Johansson\, Infrastructure Coordinator SciLifeLab \n\n\n\n \n\n\n\n\n\n\n\n \n\n\n\nMeet the speakers\n\n\n\n\n\n\n\n\n\nDr. Kelly Vere\, MBE\, is Director of Technical Strategy at the University of Nottingham\, UK. She is a passionate advocate for technical skills\, roles and careers and has created\, facilitated and led a number of opportunities for the technical community\, including the new UK Institute for Technical Skills & Strategy and the Technician Commitment initiative. \n\n\n\nKeynote \n\n\n\nA path for everyone: creating sustainable scientific careers \n\n\n\nFrom the shadows to the spotlight: the UK’s approach to elevating technical contributions to research and innovation \n\n\n\n\n\n\n\n\n\nAlessio Ciulli is Professor of Chemical and Structural Biology and Director of the Centre for Targeted Protein Degradation\, University of Dundee\, UK. At Facility Forum\, he will present a keynote about the importance of self-leadership\, engagement\, and inclusion to build a successful team. \n\n\n\nKeynote \n\n\n\nTeam building\, leadership\, inclusion and good competition \n\n\n\nThe importance of self-leadership\, engagement\, and inclusion to build a successful team. \n\n\n\n\n\n\n\n\n\nProgram\n\n\n\n \n\n\n\nFF-ProgramDownload\n\n\n\nPractical information\n\n\n\nA Blossoming Banquet \n\n\n\nA grand banquet will take place on the evening of June 18. The theme for the dinner will be a floral celebration – so wear your flowery dress\, hat or suit! And\, your creative skills may be put to the test! \n\n\n\nThe Facility Forum Podcast \n\n\n\nContribute and make your voice heard in the Facility Forum Podcast. Submit your wish to join here.  Kindly include a few lines about your role and a story you would like to highlight. \n\n\n\n \n\n\n\nBus transfer from/to Uppsala \n\n\n\nSciLifeLab will provide direct bus transfer from Uppsala (BMC) to the venue\, and back. The bus departs from Uppsala BMC\, June 18\, 07:45\, and from Clarion Sign at 15:30 on Wednesday\, June 19.  \n\n\n\nCloakroom & Registration  \n\n\n\nLeave your luggage in the cloakroom\, staffed from 09 to 17 on Tuesday and from 08 to 16 on Wednesday. We can not accept luggage other than small handbags and regular (e.g.\, laptop) backpacks in the Big Hall. \n\n\n\nRegistration opens at 09:00 at the Clarion Sign; the registration area is next to the Conference entrance. Register by showing the QR code that will be emailed to you shortly before the Conference. The nametags are sorted by Last name. \n\n\n\nHotel check-in/out \n\n\n\nCheck-in: The room will be available from 16:00. Rooms at Clarion Sign are available outside the lecture all after the end of the day’s sessions. \n\n\n\nAbout 100 participants are staying at Clarion Hotel Amaranten\, 10 minute walk from Clarion Sign. You will find your keycard at Amaranten. \n\n\n\nCheck-out: Leave the key card by the Hotel reception desk after breakfast. Put your luggage in the cloakroom. To facilitate check-out\, you cannot put anything on the room bill\, such as snacks and drinks or a bar tab. \n\n\n\n \n\n\n\nWorkshops\n\n\n\nThere will be three rounds of workshops\, with two taking place on both Tuesday and Wednesay. The Session “Hands-on with Large Language Models” is part of the plenary program. Workshop instructions has been sent out in advance. \n\n\n\n\n\n\n\nList of workshopsDownload
URL:https://www.scilifelab.se/event/facility-forum-2024/
LOCATION:Clarion Sign Hotel\, Östra Järnvägsgatan 35\, Stockholm\, Stockholm\, 111 20\, Sweden
CATEGORIES:Community
ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2023/10/Facility-Forum-Square.png
ORGANIZER;CN="SciLifeLab Event":MAILTO:events@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20240619T090000
DTEND;TZID=Europe/Stockholm:20240619T120000
DTSTAMP:20260407T133456
CREATED:20240614T151702Z
LAST-MODIFIED:20240614T151815Z
UID:10001276-1718787600-1718798400@www.scilifelab.se
SUMMARY:Uppsala University DDLS Fellows - public seminars with candidates
DESCRIPTION:Evolution and Biodiversity in the light of massive data details\n\n\n\nMeeting details\n\n\n\nWednesday\, June 19\, 2024 9:00-12:00 \n\n\n\nLocation: Lindahl-hall\, EBC Uppsala University. The meeting will also be on Zoom. Join us on: Zoom link >>   \n\n\n\nPasscode: DDLS \n\n\n\nSchedule\n\n\n\n9.00-9.15 Welcome9.15-9.45 Jennifer James: Investigating proteome trends: Evolution over huge timescales10.00-10.30 Julia V. Tavares: Forest sensitivity and resilience to climatic and hydrological changes10.45-11.15 Laura Antao: Elucidating biodiversity change in the Anthropocene11.30-12.00 Darrin Schultz: Chromosome structure as an evolutionary ledger
URL:https://www.scilifelab.se/event/uppsala-university-ddls-fellows-public-seminars-with-candidates-evolution-and-biodiversity-in-the-light-of-massive-data/
CATEGORIES:Event
ORGANIZER;CN="SciLifeLab Event":MAILTO:events@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20240620T120000
DTEND;TZID=Europe/Stockholm:20240620T130000
DTSTAMP:20260407T133456
CREATED:20240102T100557Z
LAST-MODIFIED:20240619T094614Z
UID:10001097-1718884800-1718888400@www.scilifelab.se
SUMMARY:Campus Solna Seminar Series: Ivan Tolstoganov
DESCRIPTION:Welcome to join the Campus Solna Seminar Series – an  initiative to promote the fantastic science ongoing at Campus Solna and hopefully forge more internal communication and collaboration between within Campus Solna. The format consists of two 15 min talks (One speaker from the Alpha-building and one from the Gamma-building respectively)\, with an additional 5 min of questions. Presentation of ongoing (unpublished) projects is strongly encouraged. \n\n\n\nThe seminars are held Thursdays 12:00-13:00. You can bring your lunch to the seminar. \n\n\n\nThis week:\n\n\n\n\n\n\nIvan Tolstoganov\n\n\n\nKristoffer Sahlin – gamma 6 \n\n\n\nMulti-context seeds enable higher short read mapping accuracy in StrobeAlign \n\n\n\n\n\n\n\n\n\n \n\n\n\n \n\n\n\n\n\n\nThis seminar series is organized by the PhD & Postdoc Council. For more information about the Council and other events check our page.
URL:https://www.scilifelab.se/event/campus-solna-seminar-series-sanem-sariyar-ivan-tolstoganov/
LOCATION:Air&Fire\, SciLifeLab Stockholm\, Tomtebodavägen 23A\, Solna\, Sweden
CATEGORIES:Community
ATTACH;FMTTYPE=image/jpeg:https://www.scilifelab.se/wp-content/uploads/2022/09/IMG_20221103_123412496_HDR2-scaled.jpg
ORGANIZER;CN="SciLifeLab Solna PhD & Postdoc Council":MAILTO:phd-council@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20240625T150000
DTEND;TZID=Europe/Stockholm:20240625T160000
DTSTAMP:20260407T133456
CREATED:20240527T111108Z
LAST-MODIFIED:20240528T075050Z
UID:10001267-1719327600-1719331200@www.scilifelab.se
SUMMARY:[Spotlight seminar]- Ralf Jungmann
DESCRIPTION:Ralf Jungmann\, Professor at Ludwig-Maximilians-Universisty (LMU) and Max-Planck-Institut for Biochemistry\, Germany \n\n\n\nSeminar: Localizomics: towards spatial omics using DNA-based super-resolution microscopy\n\n\n\nI will discuss our group’s vision of converting standard off-the-shelf fluorescence microscopy hardware into a tool for spatial omics. I will introduce technical advancements in DNA-PAINT including approaches that achieve sub-nanometer spatial resolution and spectrally unlimited multiplexing in whole cells. I will then discuss protein labeling probes such as Slow Off-rate Modified Aptamers (SOMAmers) that could allow DNA-barcoded labeling of much of the proteome in a cellular environment. Next\, I present approaches to increase DNA-PAINT’s traditionally slow imaging speeds to achieve throughputs necessary for network-wide molecular interrogation.  Finally\, I will present cell surface receptor quantification at thus far elusive resolutions and levels of multiplexing. \n\n\n\nBio\n\n\n\nRalf Jungmann’s interdisciplinary research is aimed at developing novel imaging tools for biological and biomedical applications. Specifically\, structural and dynamic DNA nanotechnology are combined with single-molecule fluorescence methods. The novel imaging tools unravel position and interplay of genes\, RNAs and proteins in cells in a truly quantitative way with ultrahigh resolving power.Read more: https://www.biochem.mpg.de/jungmann \n\n\n\nHost: Hans Blom\, KTH\, hblom@kth.se
URL:https://www.scilifelab.se/event/spotlight-seminar-ralf-jungmann/
LOCATION:Air&Fire\, SciLifeLab Stockholm\, Tomtebodavägen 23A\, Solna\, Sweden
CATEGORIES:Event
ATTACH;FMTTYPE=image/jpeg:https://www.scilifelab.se/wp-content/uploads/2023/10/Campus-solna-seminar-picture.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20240626T102000
DTEND;TZID=Europe/Stockholm:20240626T112000
DTSTAMP:20260407T133456
CREATED:20240312T093603Z
LAST-MODIFIED:20240614T152903Z
UID:10001201-1719397200-1719400800@www.scilifelab.se
SUMMARY:Biodiversitetskrisen hotar hållbarhet och bioekonomi – kan svensk forskning vara lösningen?
DESCRIPTION:Planeten vi bebor förändras allt snabbare. Inom kort kan många ikoniska arter vara ett minne blott; ål\, flodkräfta och fjälluggla bland flera andra. Vi måste studera dessa\, för att kunna rädda dem\, innan det är för sent. Hjälp svenska forskare att hjälpa svensk natur! \n\n\n\nTill följd av klimatförändringar och mänsklig påverkan\, förloras biodiversitet och livsviktiga ekosystemtjänster i alarmerande takt. En stor utmaning är nu att förstå konsekvenserna och föreslå motåtgärder. För att möjliggöra detta\, bör arvsmassan från så många arter som möjligt kartläggas. Med detta syfte startades Earth Biogenome Project (EBP) år 2019 för att ge forskare verktyg att kartlägga förlust av mångfald\, rädda hotade arter\, finna nya läkemedel\, och säkerställa födotillgång för världens ökande befolkning. EBP är ett globalt nätverk av nationella och regionala projekt. Sverige är dessvärre ett av få i-länder som ännu inte har ett nationellt delprojekt. Anledningen till detta är att nödvändiga ekonomiska resurser inte avsatts. För att spela en aktiv roll och ta hänsyn till den biologiska mångfalden som kännetecknar vårt land\, behövs strategiskt ekonomiskt stöd. Svenska forskare och forskningsinfrastruktur är redo. Men vem kommer att backa upp oss? \n\n\n\n\n\n\n\nMedverkande\n\n\n\nOlga Vinnere Pettersson\, Scientific Lead of Planetary Biology Capability\, SciLifeLabAndreas Wallberg\, Forskare\, Uppsala UniversitetMats Svensson\, Avdelningchef\, Havs- och vattenmyndighetenCharlotta Berggren\, VVS-konsult\, ByDemandAnna Wetterbom\, Moderator\, SBDI \n\n\n\n\n\n\n\n\n\n\n\nKontakt:  \n\n\n\nOlga Vinnere Pettersson\, Uppsala universitet\, Olga.Pettersson@scilifelab.uu.se
URL:https://www.scilifelab.se/event/biodiversitetskrisen-och-genetisk-forskning-vad-ar-sveriges-svar/
LOCATION:Yoda Bar & Café\, Skeppsbron 24\, Visby\, Sweden
CATEGORIES:Event
ATTACH;FMTTYPE=image/jpeg:https://www.scilifelab.se/wp-content/uploads/2023/08/Almedalen-2023-2-scaled.jpeg
ORGANIZER;CN="SciLifeLab i Almedalen":MAILTO:events@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20240626T130000
DTEND;TZID=Europe/Stockholm:20240626T140000
DTSTAMP:20260407T133456
CREATED:20240312T093837Z
LAST-MODIFIED:20240614T152954Z
UID:10001202-1719406800-1719410400@www.scilifelab.se
SUMMARY:Inför nästa pandemi - hur behåller vi och utvecklar viktig laboratoriekunskap och teknik?
DESCRIPTION:Under denna pandemi har vi förbättrat vår förmåga att hantera pandemier\, men hur behåller vi och utvecklar viktig laboratoriekunskap och teknik till nästa pandemi/hälsokris? \n\n\n\nCOVID-19 pandemin har gått in i en post-pandemisk fas men nya pandemier kommer drabba oss. Tidigt under pandemin blev det uppenbart att Sverige hade begränsade resurser att analysera prover från alla potentiellt infekterade\, vilket negativt påverkade möjligheten att kontrollera smittspridningen. En solid\, tillgänglig och högteknologisk plattform saknades för att skapa samarbeten och utbyten mellan sjukhusens mikrobiologiska laboratorier\, akademiska forskare\, och myndigheter. Ny forskning behövdes för att förstå detta nya virus och nya tekniker behövde utvecklas för att kunna följa utvecklingen av och kontrollera pandemin. Därför fick SciLifeLab i slutet av 2020 uppdraget från regeringen att utveckla Pandemisk Laborativ Beredskap\, och har nu byggt upp nationell kapacitet i Sverige för att hantera pandemier och andra biologiska hot framöver. Men är det något som saknas? Hur säkerställer vi att denna kapacitet och kunskap underhålls och utvecklas vidare? Vem ska göra vad? \n\n\n\nMedverkande\n\n\n\nStaffan Svärd\, Professor\, Uppsala Universitet och SciLifeLabUlf Ribacke\, Co-director PLP\, Uppsala Universitet\, SciLIfeLab och Karolinska InstitutetMia Philipson\, Professor och Co-director\, Uppsala Universitet och SciLIfeLabJens Mattsson\, Generaldirektör\, Totalförsvarets forskningsinstitut (FOI)Sara Byfors\, Avdelningschef\, Folkhälsomyndigheten (FoHM)Niklas Arnberg\, Professor och generalsekreterare\, Umeå Universitet och Virus – och pandemifondenBengt Mattson\, Hållbarhetsansvarig\, Lif- de forskande läkemedelsföretagen \n\n\n\n\n\n\n\n\n\n\n\nKontakt:  \n\n\n\nAlice Sollazzo\, SciLifeLab\, alice.sollazzo@scilifelab.uu.se
URL:https://www.scilifelab.se/event/infor-nasta-pandemi-hur-behaller-vi-och-utvecklar-viktig-laboratoriekunskap-och-teknik/
LOCATION:D-huset\, Campus Gotland\, Kaserngatan 1\, Visby\, Sweden
CATEGORIES:Event
ATTACH;FMTTYPE=image/jpeg:https://www.scilifelab.se/wp-content/uploads/2023/08/Almedalen-2023-2-scaled.jpeg
ORGANIZER;CN="SciLifeLab i Almedalen":MAILTO:events@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20240626T160000
DTEND;TZID=Europe/Stockholm:20240626T170000
DTSTAMP:20260407T133456
CREATED:20240312T094238Z
LAST-MODIFIED:20240614T153131Z
UID:10001203-1719417600-1719421200@www.scilifelab.se
SUMMARY:Framtidens hälso- och sjukvård och forskning möjliggörs tack vare europeisk satsning på genomikdata
DESCRIPTION:För förbättrad sjukvård (precisionsmedicin) och ökad kunskap om genetisk variation arbetar Europa tillsammans för att ge forskare och läkare tillgång till viktiga genomikdata. Med lagstiftning på hälsodataområdet och säker tillgång till data skapas nya möjligheter för framtidens sjukvård och forskning. \n\n\n\nSeminarium men initiala korta presentationer om de pågående initiativen följt av paneldiskussion och frågor från auditoriet. a) De korta presentationerna kommer att vara kring: i) Det europeiska 1+Million Genome Project\, som Sverige och 23 andra länder är engagerade i. ii) Byggande av en europeisk genomikdatainfrastruktur (GDI) iii) Ny lagstiftning inom hälsodataområdet (EHDS) iv) Precisionsmedicinens möjligheter för medborgare\, patienter och forskare b) Paneldiskussion med företrädare för genomikinfrastrukturen\, sjukvården\, precisionsmedicin\, e-hälsomyndigheten\, patientföreningar och juridisk kompetens. c) Tillfälle för publiken att ställa frågor så att vi får en öppen diskussion med tillfälle till fördjupning. \n\n\n\nMedverkande\n\n\n\nBengt Persson\, Professor i bioinformatik\, Uppsala Univ\, SciLifeLab\, NBIS\, ELIXIRRichard Rosenquist Brandell\, Professor och överläkare i klinisk genetik\, Karolinska Institutet\, Karolinska Universitetssjukhuset\, Genomic Medicine SwedenÅsa Johansson\, Universitetslektor och Vetenskaplig ledare för Precisionsmedicin\, Uppsala Univ\, SciLifeLabManólis Nymark\, Jurist\, European 1+ Million Genome projectMichel Silvestri\, Enhetschef\, med dr\, E-hälsomyndighetenJohan Viklund\, Teknisk chef\, Uppsala Univ\, SciLifeLab\, NBIS\, ELIXIR \n\n\n\nKontakt \n\n\n\nBengt Persson\, Uppsala universitet\, bengt.persson@icm.uu.se
URL:https://www.scilifelab.se/event/framtidens-halso-och-sjukvard-och-forskning-mojliggors-tack-vare-europeisk-satsning-pa-genomikdata/
LOCATION:D-huset\, Campus Gotland\, Kaserngatan 1\, Visby\, Sweden
CATEGORIES:Event
ATTACH;FMTTYPE=image/jpeg:https://www.scilifelab.se/wp-content/uploads/2023/08/Almedalen-2023-2-scaled.jpeg
ORGANIZER;CN="SciLifeLab i Almedalen":MAILTO:events@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20240627T113000
DTEND;TZID=Europe/Stockholm:20240627T123000
DTSTAMP:20260407T133456
CREATED:20240312T093325Z
LAST-MODIFIED:20240614T153257Z
UID:10001200-1719487800-1719491400@www.scilifelab.se
SUMMARY:Hur kan storskaliga molekylära analyser leda till precisionshälsa?
DESCRIPTION:Molekylära analyser kan möjliggöra preventiva insatser\, tidig diagnos och individanpassad behandling. Hur kan vi underlätta införandet av nya teknologier för precisionshälsa i hälso- och sjukvården? Och vilka långsiktiga ekonomiska och hälsomässiga fördelar kan detta ha för samhället? \n\n\n\n\n\n\n\nSverige har en världsunik forskningsinfrastruktur för molekylära analyser och spetskompetens inom dataanalys. Vi har även byggt upp starka nätverk mellan akademi och sjukvårdsregioner för implementering av genetiska analyser i klinisk rutin. Hur kan vi på bästa sätt nyttja och bygga vidare på dessa resurser för att skala upp genereringen av molekylära data inom hälso- och sjukvården? Kan storskaliga molekylära analyser bidra till att hälso- och sjukvården ökar sitt fokus på förebyggande åtgärder och tidig diagnostik? Hur kan vi hitta en modell för att på ett smidigt sätt testa och integrera nya teknologier för precisionshälsa inom vården och vem ansvarar för vad i processen – vad är akademins\, regionernas och industrins roll? \n\n\n\nMedverkande\n\n\n\nAnders Hagfeldt\, rektor\, UUÅsa Johansson\, doc. i molekylär epidemiologi\, UU\, SciLifeLabFrida Lundmark\, sakkunnig policy\, Lif – de forskande läkemedelsföretagenMarie Morell\, ordf. Regionstyrelsen\, Region ÖstergötlandRichard Rosenquist Brandell\, prof. och överläkare i klinisk genetik\, KI\, Karolinska Universitetssjukhuset\, GMSPatrik Rossi\, tf. sjukhusdirektör\, Karolinska UniversitetssjukhusetMia Phillipson\, moderator\, UU\, SciLifeLab \n\n\n\nArrangörsuppgifter:\n\n\n\nKontakt:  \n\n\n\nÅsa Johansson\, Uppsala universitet\, SciLifeLab\, Genomic Medicine Sweden\, asa.johansson@igp.uu.se \n\n\n\nEva Berglund\, Uppsala universitet\, SciLifeLab\, eva.berglund@scilifelab.uu.se
URL:https://www.scilifelab.se/event/hur-kan-storskaliga-molekylara-analyser-leda-till-precisionshalsa/
LOCATION:D-huset\, Campus Gotland\, Kaserngatan 1\, Visby\, Sweden
CATEGORIES:Event
ATTACH;FMTTYPE=image/jpeg:https://www.scilifelab.se/wp-content/uploads/2023/08/Almedalen-2023-2-scaled.jpeg
ORGANIZER;CN="SciLifeLab i Almedalen":MAILTO:events@scilifelab.se
END:VEVENT
END:VCALENDAR