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BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20241202T090000
DTEND;TZID=Europe/Stockholm:20241206T170000
DTSTAMP:20260421T173342
CREATED:20240913T103340Z
LAST-MODIFIED:20241129T105934Z
UID:10001354-1733130000-1733504400@www.scilifelab.se
SUMMARY:Population genomics in practice - Cancelled
DESCRIPTION:Note – this course has been cancelled. National course open for PhD students\, postdocs\, researchers and other employees in all Swedish universities\, in need of  hands-on and practical skills for the analyses of population genomics data. We also welcome applications from outside of Sweden and from the non-academic sector\, for more info contact us! \n\n\n\n\n\n\n\nImportant dates and information\n\n\n\nApplication opens: 2024-09-09 \n\n\n\nApplication closes: 2024-10-15 \n\n\n\nConfirmation to accepted students: 2024-10-30 \n\n\n\nCourse Leader and teachers: Per Unneberg (CL)\, André Soares (CL)\, Nikolay Oskolkov\, Jason Hill \n\n\n\nIn case you miss information on any of the above dates\, please contact: edu.population-genomics-in-practice@nbis.se \n\n\n\n\n\n\n\n\n\nApplication\n\n\n\n\n\nCourse website\n\n\n\n\n\n\n\n\n\nCourse fee\n\n\n\nA course fee* of 3000 SEK  for academic participants and 15000 SEK for non-academic participants will be invoiced to accepted participants. The fee includes lunches\, coffee and snacks. \n\n\n\n*Please note that NBIS cannot invoice individuals \n\n\n\n\n\n\n\nCourse content\n\n\n\nThe aim of this workshop is to provide an introduction to commonly used methods in population genomics. As the focus of the course is on hands-on work\, the topics have been designed to cover the fundamental analyses that are common in many population genomics studies. The course consists of lectures and exercises\, with a focus on the practical aspects of analyses. Whereas lectures introduce some background theory\, their primary aim is to set the stage for accompanying exercises. \n\n\n\nTopics covered will include: \n\n\n\n\nFoundations of population genetics\n\n\n\nIntroduction to simulation and the coalescent\n\n\n\nBasics of variant calling\n\n\n\nVariant filtering and sequence masks\n\n\n\nCharacterization and interpretation of DNA sequence variation\n\n\n\nCalculation and interpretation of summary statistics from variation data\n\n\n\nInvestigating population structure with admixture modelling and principal component analyses\n\n\n\nDemographic modelling using sequentially Markovian coalescent models and linkage disequilibrium\n\n\n\nSelection scans\n\n\n\n\n\n\n\n\n\n\nLearning Outcomes\n\n\n\nUpon completion of this course\, you will be able to: \n\n\n\n\ndescribe the different forces of evolution and how they influence genetic variation\n\n\n\nunderstand and interpret genealogical trees and how they relate to genetic variation data\n\n\n\ndescribe the basics of the coalescent\n\n\n\nperform simple coalescent simulations with msprime\n\n\n\nrun simple SLiM forward simulation models\n\n\n\ndescribe and run the steps of a variant calling pipeline\, including quality control of raw reads\, read mapping\, and variant calling\n\n\n\nknow how and when to filter raw variant calls using manual coverage filters\n\n\n\ndescribe and calculate nucleotide diversity from variation data\n\n\n\nanalyse population structure with admixture modelling and dimensionality reduction methods\n\n\n\nperform demographic modelling with sequential Markovian coalescent models\n\n\n\ndescribe methods that identify regions undergoing adaptation and selection\n\n\n\nrun selection scans\, score identified regions and interpret findings in the context of genome annotations\n\n\n\n\n\n\n\n\nEntry requirements\n\n\n\nThe following is a list of skills required for being able to follow the course and complete the exercises: \n\n\n\n\nBasic knowledge in R or Python\n\n\n\nBasic knowledge of variant calling\, or the equivalent of NBIS course “Introduction to Bioinformatics using NGS data”\n\n\n\nBasic knowledge of population genetics\n\n\n\nBasic understanding of frequentist statistics\n\n\n\nA computer\n\n\n\n\nDesirable\, but not essential\, skills increasing the output of the course\, include: \n\n\n\n\nExperience with analysis of NGS and other omic data\n\n\n\n\n\n\n\n\nDue to limited space the course can accommodate a maximum of 25 participants. If we receive more applications\, participants will be selected based on selection criteria\, including (but not limited to) correct entry requirements\, motivation to attend the course\, as well as gender and geographical balance.
URL:https://www.scilifelab.se/event/population-genomics-in-practice-2/
LOCATION:Navet\, SciLifeLab Uppsala\, SciLifeLab Uppsala\, BMC C11\, Husargatan 3\, Uppsala\, 75237\, Sweden
CATEGORIES:Course
ORGANIZER;CN="NBIS - National Bioinformatics Infrastructure Sweden":MAILTO:education@nbis.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20241202T151500
DTEND;TZID=Europe/Stockholm:20241202T161500
DTSTAMP:20260421T173342
CREATED:20241118T142548Z
LAST-MODIFIED:20241120T081943Z
UID:10001404-1733152500-1733156100@www.scilifelab.se
SUMMARY:[The Svedberg seminar] - Diversity of left-right asymmetry among animals
DESCRIPTION:Hiroshi HamadaProfessorNational Center for Biological Sciences\, Ashoka University\, India \n\n\n\n \n\n\n\n \n\n\n\n\n\n\n\nBio\n\n\n\nProfessor Hiroshi Hamada is a visiting professor at National Center for Biological Sciences in Ashoka University\, India. Professor Hamada received his M.D from Okayama University in 1975 and his PhD from the same university in 1979. Since then he has worked at several prestigious institutions such as NIH and RIKEN. He has been an associate editor and part of the editorial board on a number of journals within the medical field. \n\n\n\nDiversity of left-right asymmetry among animals\n\n\n\nMost of animals exhibit left-right (L-R) asymmetries in internal and/or superficial organs\, but they employ different mechanisms for L-R asymmetry\, especially for symmetry breaking. Many vertebrates including fish\, amphibians and mammals\, use motile cilia to generate unidirectional fluid flow at the left-right organizer\, for symmetry breaking. Birds and reptiles\, however\, break L-R symmetry without motile cilia\, but its mechanism remains unknown. Invertebrates such as insects and snails employ a variety of different mechanisms. We studied the genetic pathway that establishes L-R asymmetry in the mouse\, but we are now investigating how chick embryos establish molecular L-R asymmetry without cilia. Also\, we have started to investigate how snail embryos establish L-R asymmetric gene expression. I would like to introduce our current attempts with chick and snail embryos. \n\n\n\n \n\n\n\n \n\n\n\n \n\n\n\n\n\n\n\nHost: Gonzalo Sanchez\, UU gonzalo.sanchez@mcb.uu.se
URL:https://www.scilifelab.se/event/the-svedberg-seminar-diversity-of-left-right-asymmetry-among-animals/
LOCATION:BMC Room C8:301\, Husargatan 3\, Uppsala\, Sweden
CATEGORIES:Event
ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2022/02/Picture1-The-Svedberg.png
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20241203T150000
DTEND;TZID=Europe/Stockholm:20241203T153000
DTSTAMP:20260421T173342
CREATED:20241126T090741Z
LAST-MODIFIED:20241126T090742Z
UID:10001409-1733238000-1733239800@www.scilifelab.se
SUMMARY:Psychological Safety at Work
DESCRIPTION:Psychological safety is essential for every thriving workplace\, enhancing job satisfaction and performance. In this seminar\, we will explore what psychological safety is\, how it boosts team and individual success\, and the stages involved – from fostering inclusion to encouraging constructive feedback and critical thinking. Insights from key research will highlight practical ways to build a culture of trust and growth. \n\n\n\nZoom link
URL:https://www.scilifelab.se/event/psychological-safety-at-work/
LOCATION:Hybrid event in Gamma 2 lunchroom and zoom\, Tomtebodavägen 23 B\, Solna\, 17165\, Sweden
CATEGORIES:Community
ATTACH;FMTTYPE=image/png:https://www.scilifelab.se/wp-content/uploads/2024/09/CSI_logo_square.png
ORGANIZER;CN="Coaching in Science Initiative (CSI)":MAILTO:sami.saarenpaa@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20241204T143000
DTEND;TZID=Europe/Stockholm:20241204T150000
DTSTAMP:20260421T173342
CREATED:20241122T101542Z
LAST-MODIFIED:20241203T150445Z
UID:10001408-1733322600-1733324400@www.scilifelab.se
SUMMARY:Pfizer Discovery Network introduction
DESCRIPTION:Listen in and learn more about how Pfizer discovery network operate and get info about upcoming possibilities. \n\n\n\nThis is an event organised by SciLifeLab external relations in collaboration with Pfizer discovery network. The introduction is followed by individual pitch-sessions offered to SciLifeLab researchers earlier in the fall (via an open call\, now closed). You are most welcome to listen in even if you are not pitching afterwards. \n\n\n\nAlso\, don’t miss out on an up-coming call where Pfizer is seeking proposals to support early drug discovery efforts in: Novel technologies for cellular phenotyping at scale and Models and biomarkers for neuroinflammation. \n\n\n\nProgram: 1. Marois Dimitriou (Pfizer): Discovery Network Introduction. 2. Katrina Loomis (Pfizer): Call for proposals according to below.3. Time for questions from the audience.
URL:https://www.scilifelab.se/event/pfizer-discovery-network-introduction/
LOCATION:Online event via Zoom
CATEGORIES:Event
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20241205T120000
DTEND;TZID=Europe/Stockholm:20241205T130000
DTSTAMP:20260421T173342
CREATED:20240708T145424Z
LAST-MODIFIED:20241203T090651Z
UID:10001306-1733400000-1733403600@www.scilifelab.se
SUMMARY:Campus Solna Seminar Series: Varun Kumar Rajendran & Marta Bonaccorsi
DESCRIPTION:Welcome to join the Campus Solna Seminar Series – an initiative to promote the fantastic science ongoing at Campus Solna and hopefully forge more internal communication and collaboration between within Campus Solna. The format consists of two 20 min talks (One speaker from the Alpha-building and one from the Gamma-building respectively)\, with an additional 5 min of questions. Presentation of ongoing (unpublished) projects is strongly encouraged. \n\n\n\nThe seminars are held Thursdays 12:00-13:00. You can bring your lunch to the seminar. \n\n\n\nPhD students that are attending the Campus Solna Seminar lectures will have the opportunity to gain credits. For the syllabus and instructions on how to obtain these credits\, read this document. Please contact your own department at your host University to confirm.See here the full schedule for this semester. \n\n\n\nThis week:\n\n\n\n\n\n\nVarun Kumar Rajendran\n\n\n\nMartin Viklund – gamma 3 \n\n\n\nAcoustofluidic sample delivery systems for X-ray crystallography \n\n\n\n\n\nMarta Bonaccorsi\n\n\n\nLucie Delemotte – gamma 3 \n\n\n\nInvestigating the conformational landscape of sugar transporters \n\n\n\n\n\n\nThis seminar series is organized by the PhD & Postdoc Council. For more information about the Council and other events check our page.
URL:https://www.scilifelab.se/event/campus-solna-seminar-series-greta-gudoityte-marta-bonaccorsi/
LOCATION:Air&Fire\, SciLifeLab Stockholm\, Tomtebodavägen 23A\, Solna\, Sweden
CATEGORIES:Community
ATTACH;FMTTYPE=image/jpeg:https://www.scilifelab.se/wp-content/uploads/2022/09/IMG_20221103_124630107_HDR-scaled.jpg
ORGANIZER;CN="SciLifeLab Solna PhD & Postdoc Council":MAILTO:phd-council@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20241210T090000
DTEND;TZID=Europe/Stockholm:20241210T161500
DTSTAMP:20260421T173342
CREATED:20241029T154840Z
LAST-MODIFIED:20241206T135109Z
UID:10001389-1733821200-1733847300@www.scilifelab.se
SUMMARY:4th users meeting - Integrated Structural Biology SciLifeLab
DESCRIPTION:Welcome to the 4th annual users meeting within Integrated Structural Biology in Sweden! \n\n\n\nWe hope to hear from the community and encourage you to send in a short abstract from which we will select users/students/postdocs to give a 15 min presentation. Please upload your abstract (maximum 600 characters in the registration form) if you would like to be considered for an oral presentation. \n\n\n\nregistration\n\n\n\nThose of you who are selected for a presentation will have their travel expenses covered as well as one hotel night (Dec 9) if travelling from outside Stockholm/Uppsala. \n\n\n\nFor any questions\, don’t hesitate to contact Cecilia Persson (cecilia.persson@nmr.gu.se) \n\n\n\nProgram\n\n\n\n4th users meeting – Integrated Structural Biology SciLifeLabDownload
URL:https://www.scilifelab.se/event/4th-users-meeting-integrated-structural-biology-scilifelab/
LOCATION:Air&Fire\, SciLifeLab Stockholm\, Tomtebodavägen 23A\, Solna\, Sweden
CATEGORIES:Event
ORGANIZER;CN="Integrated Structural Biology Platform at SciLifeLab":MAILTO:cecilia.persson@nmr.gu.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20241211T083000
DTEND;TZID=Europe/Stockholm:20241211T153000
DTSTAMP:20260421T173342
CREATED:20241024T060207Z
LAST-MODIFIED:20241121T102250Z
UID:10001386-1733905800-1733931000@www.scilifelab.se
SUMMARY:SciLifeLab & AAAS/Science Publishing Workshop for Junior Researchers 2024
DESCRIPTION:Applications are now welcome for participation in this highly regarded and rewarding interactive workshop by Science and SciLifeLab. Designed for early career researchers (PhD students and postdocs) in SciLifeLab:s research community\, the workshop focuses on the publishing landscape\, paper preparation\, and the publication process. \n\n\n\n\n\n\n\nWorkshop leaders: \n\n\n\n\nValda Vinson (Executive Editor\, Science Magazine)\n\n\n\nSacha Vignieri (Deputy Editor Research\, Science Magazine)\n\n\n\n\nThe workshop is split into a hybrid morning session\, and an afternoon on-site workshop (see Curriculum for details). Questions from the participants will be addressed by the Editors in generous Q&A sessions.  \n\n\n\nOn-site participation\, including lunch and coffee breaks with the Editors\, is limited to 40 participants. Participants for the on-site workshop will be selected after the application deadline\, with consideration for gender balance\, affilitation (with aim to distribute workshop spots nationally and across all universities)\, and in case of equivalent applications\, date of application (first come\, first serve basis). \n\n\n\nDeadline for application: November 27 \n\n\n\nApply here
URL:https://www.scilifelab.se/event/scilifelab-aaas-science-publishing-workshop-for-junior-researchers-2024/
LOCATION:Air&Fire\, SciLifeLab Stockholm\, Tomtebodavägen 23A\, Solna\, Sweden
CATEGORIES:Event
ORGANIZER;CN="SciLifeLab Event":MAILTO:events@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20241211T130000
DTEND;TZID=Europe/Stockholm:20241211T160000
DTSTAMP:20260421T173342
CREATED:20241105T131701Z
LAST-MODIFIED:20241105T132546Z
UID:10001397-1733922000-1733932800@www.scilifelab.se
SUMMARY:SciLifeLab Linköping Seminar Series 2024: NBIS
DESCRIPTION:SciLifeLab Linköping invites to a seminar series with focus on our local life-science infrastructure units. \n\n\n\nHere we present the National Bioinformatics Infrastructure Sweden (NBIS)
URL:https://www.scilifelab.se/event/scilifelab-linkoping-seminar-series-2024-nbis/
LOCATION:Wrannesalen\, Campus US\, Linköping\, North entrance\, elevator K\, floor 11\, Linköping
CATEGORIES:Event
ORGANIZER;CN="SciLifeLab Link%C3%B6ping":MAILTO:linkoping@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20241211T153000
DTEND;TZID=Europe/Stockholm:20241212T150000
DTSTAMP:20260421T173342
CREATED:20241106T142016Z
LAST-MODIFIED:20241202T124046Z
UID:10001399-1733931000-1734015600@www.scilifelab.se
SUMMARY:SciLifeLab Research Data Management Roadshow in Lund
DESCRIPTION:SciLifeLab Data Centre and NBIS\, in collaboration with SciLifeLab Lund\, welcome you to join a 2-day event with presentations\, workshops\, & networking.  \n\n\n\nSciLifeLab Data Management is a collaborative activity between SciLifeLab Data Centre and NBIS Data Management team. Together we support and collaborate with the Swedish life sciences research community and infrastructure. Our aims are to: maximize the value of life science data\, highlight and disseminate information about Open Science\, FAIR\, and good RDM practices\, offer services\, tools\, and support\, and offer courses and training. SciLifeLab Research Data Management Roadshow will visit all SciLifeLab sites during 2024 and 2025. \n\n\n\nDuring the Roadshow in Lund\, the following activities are offered: \n\n\n\n\nSeminar “Overview of Research Data Management services and support available locally and from SciLifeLab”\, 11 Dec 15:30-16:30 (fika will be served from 15)\,  Belfragesalen\, BMC D15Target group: PhD students\, postdocs\, researchers and infrastructure staff\n\n\n\nFAIR Frukost\, 12 Dec\, 9:00-10:00\, (BMC:E11079 Dialogen)Target group: PhD students and postdocs\n\n\n\nWorkshops\, 12 Dec\,Part I: Data Management Plans\, 10:00-12:00 (BMC:E11079 Dialogen)Part II: Data submission to public repositories\, 13:00-15:00 (BMC:E11073 Rådslaget)\n\n\n\n\nTarget group: PhD students\, postdocs\, researchers and infrastructure staff \n\n\n\nRegistration deadline: December 9th \n\n\n\nRegister Here
URL:https://www.scilifelab.se/event/scilifelab-research-data-management-roadshow-in-lund/
LOCATION:BMC – Biomedical Centre (Lund)\, Sölvegatan 19\, Lund\, 22362\, Sweden
CATEGORIES:Event
ORGANIZER;CN="SciLifeLab Data Centre":MAILTO:datacentre@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20241212T090000
DTEND;TZID=Europe/Stockholm:20241212T130000
DTSTAMP:20260421T173342
CREATED:20241021T090522Z
LAST-MODIFIED:20241202T132758Z
UID:10001376-1733994000-1734008400@www.scilifelab.se
SUMMARY:Science & SciLifeLab Prize Scientific Symposium 2024
DESCRIPTION:Science\, the American Association for the Advancement of Science (AAAS)\, and SciLifeLab joined forces in 2013\, creating the Science & SciLifeLab Prize for Young Scientists to recognize excellence amongst young researchers from around the world. A global Prize aimed at rewarding scientists at an early stage of their careers. \n\n\n\nThe Prize is awarded in four different categories and the four winners are; \n\n\n\n\nAndrija Sente\, Grand Prize Winner in Cell and Molecular Biology\n\n\n\nJarrod Shilts\, Category Winner in Genomics\, Proteomics\, and Systems Biology Approaches\n\n\n\nSabrina Rondeau\, Category Winner in Ecology and Environment\n\n\n\nGabriele Casirati\, Category Winner in Molecular Medicine\n\n\n\n\nRead more about each winner by clicking their names \n\n\n\nAll four winners of the Science & SciLifeLab Prize for Young Scientists are invited to Sweden December 8-13 to participate in a unique week filled with events in honor of science. They will have the opportunity to meet with leading scientists in their field of research and create life-long connections to support their careers. \n\n\n\nWelcome to the Scientific Symposium where the winners of the 2024 Science & SciLifeLab Prize for Young Scientists will present their research. \n\n\n\nThe symposium will take place at beautiful Hasselbacken at Djurgården in Stockholm. \n\n\n\nSeats are limited so register today for your chance to meet with the winners and the the AAAS/Science editor team AND our honorary guest\, the Grand Prize Winner from 2016\, Dr. Neir Eshel.  \n\n\n\n \n\n\n\n \n\n\n\nThis year’s keynote speaker is  2016 year’s Grand Prize winner Neir Eshel  \n\n\n\nPrize_speaker biographies_2024Download\n\n\n\nRegistration\n\n\n\nProgram\n\n\n\nRead more About the prize here
URL:https://www.scilifelab.se/event/science-scilifelab-prize-scientific-symposium-2024/
LOCATION:Hasselbacken\, Hazeliusbacken 20\, Stockholm\, Sweden
CATEGORIES:Event
ATTACH;FMTTYPE=image/jpeg:https://www.scilifelab.se/wp-content/uploads/2020/11/winner-photos-2020_270x170_prizepicture_black-scaled.jpg
ORGANIZER;CN="Science/AAAS and SciLifeLab":MAILTO:events@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20241212T120000
DTEND;TZID=Europe/Stockholm:20241212T130000
DTSTAMP:20260421T173342
CREATED:20240708T145600Z
LAST-MODIFIED:20241209T091859Z
UID:10001307-1734004800-1734008400@www.scilifelab.se
SUMMARY:Campus Solna Seminar Series: Jessika Jessika & Axel Knave
DESCRIPTION:Welcome to join the Campus Solna Seminar Series – an initiative to promote the fantastic science ongoing at Campus Solna and hopefully forge more internal communication and collaboration between within Campus Solna. The format consists of two 20 min talks (One speaker from the Alpha-building and one from the Gamma-building respectively)\, with an additional 5 min of questions. Presentation of ongoing (unpublished) projects is strongly encouraged. \n\n\n\nThe seminars are held Thursdays 12:00-13:00. You can bring your lunch to the seminar. \n\n\n\nPhD students that are attending the Campus Solna Seminar lectures will have the opportunity to gain credits. For the syllabus and instructions on how to obtain these credits\, read this document. Please contact your own department at your host University to confirm.See here the full schedule for this semester. \n\n\n\nThis week:\n\n\n\n\n\n\nJessika Jessika\n\n\n\nAnna Herland – alpha 4 \n\n\n\nInnovative Microdevices for Diabetes Therapeutics: Across In Vitro and In Vivo Medical Technology \n\n\n\n\n\nAxel Knave\n\n\n\nPaul Hudson – gamma 5 \n\n\n\nExploring fitness landscape of a Form II RubisCO in Synechocystis sp PCC 6803 \n\n\n\n\n\n\nThis seminar series is organized by the PhD & Postdoc Council. For more information about the Council and other events check our page.
URL:https://www.scilifelab.se/event/campus-solna-seminar-series-jessika-jessika-axel-knave/
LOCATION:Air&Fire\, SciLifeLab Stockholm\, Tomtebodavägen 23A\, Solna\, Sweden
CATEGORIES:Community
ATTACH;FMTTYPE=image/jpeg:https://www.scilifelab.se/wp-content/uploads/2022/09/IMG_20221103_120135408_HDR-scaled.jpg
ORGANIZER;CN="SciLifeLab Solna PhD & Postdoc Council":MAILTO:phd-council@scilifelab.se
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20241212T121500
DTEND;TZID=Europe/Stockholm:20241212T130000
DTSTAMP:20260421T173342
CREATED:20241203T152516Z
LAST-MODIFIED:20241203T152518Z
UID:10001413-1734005700-1734008400@www.scilifelab.se
SUMMARY:Bred sekvensering för solida tumörer (GMS560): Praxis och utblick
DESCRIPTION:I takt med att den biologiska förståelsen av solida tumörer har ökat så har arsenalen av behandlingsregimer riktade mot specifika molekylära avvikelser i cancercellerna expanderat.  \n\n\n\nI den precisionsmedicinska eran ställer detta höga krav på våra analysmetoder då vi behöver fånga en stor bredd av molekylära biomarkörer hos den enskilda patienten. Som del av ett nationellt samarbete införs GMS560 på Akademiska sjukhuset.  \n\n\n\nVälkommen till ett lunchseminarium där vi diskuterar hur analysen fungerar i praktiken\, vad vi kan rapportera idag och de biomarkörer som finns på horisonten. \n\n\n\n \n\n\n\nRead more
URL:https://www.scilifelab.se/event/bred-sekvensering-for-solida-tumorer-gms560-praxis-och-utblick/
LOCATION:Enghoffsalen\, Ingång 50 Akademiska sjukhuset\, Uppsala
CATEGORIES:Event
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20241217T151500
DTEND;TZID=Europe/Stockholm:20241217T161500
DTSTAMP:20260421T173342
CREATED:20241121T085553Z
LAST-MODIFIED:20241121T100626Z
UID:10001407-1734448500-1734452100@www.scilifelab.se
SUMMARY:Integrative Modeling of Glycoproteins
DESCRIPTION:Spotlight Seminar series welcomes Dr. Mateusz Sikora\, Head of the Dioscuri Centre for Modelling of Posttranslational Modifications\, Jagiellonian University\, Krakow\, Poland &  Max Planck Institute of Biophysics in Germany  \n\n\n\n\n\n\n\nBiography\n\n\n\nDr. Mateusz Sikora is an expert in biophysics and computational biology. He currently leads the Dioscuri Centre for Modelling of Posttranslational Modifications at Jagiellonian University\, Kraków\, Poland\, co-affiliated at the Max Planck Institute of Biophysics in Frankfurt\, Germany. His research focuses on the role of posttranslational modifications (PTMs) in protein-protein interactions\, using molecular dynamics simulations to study inherently flexible biological systems. \n\n\n\nDr. Sikora obtained his Ph.D. in Biophysics from the Institute of Physics\, Polish Academy of Sciences* in 2012\, graduating summa cum laude\, with Prof Marek Cieplak as a supervisor. His doctoral work on biomolecular dynamics and coarse-grained modeling laid the foundation for his future research into protein flexibility and interaction. He also holds an M.S. in Biophysics from Jagiellonian University. \n\n\n\nHis postdoctoral career includes notable fellowships\, including the FWF Schrödinger Fellowship (2018–2020) at the Max Planck Institute of Biophysics in Frankfurt am Main and University of Vienna\, where he worked with Gerhard Hummer and Christoph Dellago unraveling dynamic behaviour of large protein complexes\, and the EMBO Fellowship (2012–2017) at the Institute of Science and Technology (IST) in Austria with Carl Philipp Heisenberg\, where he applied cell and molecular biology experiments to understand cell-cell contact formation in zebrafish.  \n\n\n\nDr. Sikora’s work is at the intersection of computational biophysics\, structural biology\, and systems biology\, with a particular emphasis on understanding how posttranslational modifications affect the structure and function of proteins. \n\n\n\nHe has authored over 30 peer-reviewed publications (including 1st author Science\, and corresponding author Cell) and made significant contributions to the study of SARS-CoV-2\, including computational models of viral spike proteins and their interactions with host cells\, as well as new methods to study the effects of glycans on proteins. His work has been widely recognized\, with his research featured in prominent media outlets such as Science\, The New York Times\, and National Geographic. \n\n\n\nDr. Sikora has received numerous grants and awards\, including the joint Max Planck and Polish National Science Centre Dioscuri grant. He is also involved in translational research\, with patents related to posttranslational modifications for vaccine development and medical applications. \n\n\n\nWith an h-index of 17 and over 1\,700 citations\, Dr. Sikora is recognized as a leading researcher in his field\, combining advanced computational methods with experimental biology to explore critical biological processes at the molecular level. \n\n\n\nAbstract\n\n\n\nGlycans\, complex sugars covalently attached to proteins\, play crucial roles in protein stability and function\, participate in “self” recognition\, and modulate protein-protein interactions. Unlike proteins\, glycans typically do not form secondary structures and remain highly mobile\, posing challenges for traditional structural biology techniques. This high mobility\, coupled with glycan heterogeneity\, complicates the elucidation of complete glycoprotein structures and hinders research on the role of glycans in protein function. Although computer simulations can help address these challenges\, they often require millions of hours on specialized supercomputers\, highlighting the need for approximate methods that can be integrated into protein-solving pipelines. \n\n\n\nTo overcome these obstacles\, we developed a simplified\, open-source method for rapidly predicting the span and shape of glycans with minimal computing power. Using this approach\, we can accurately predict SARS-CoV-2 spike protein epitopes that are not shielded by glycans\, as well as assess the impact of glycans on protein flexibility. We also demonstrate that this method can be integrated with structural biology methods and glycoproteomics pipelines\, offering a comprehensive tool for glycoprotein analysis. \n\n\n\n\n\n\n\nHost: Piotr Draczkowski piotr.draczkowski@scilifelab.se
URL:https://www.scilifelab.se/event/integrative-modeling-of-glycoproteins/
LOCATION:Air&Fire\, SciLifeLab Stockholm\, Tomtebodavägen 23A\, Solna\, Sweden
CATEGORIES:Event
ATTACH;FMTTYPE=image/jpeg:https://www.scilifelab.se/wp-content/uploads/2023/10/Campus-solna-seminar-picture.jpg
ORGANIZER;CN="Spotlight Seminar Series":MAILTO:events@scilifelab.se
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BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20241218T110000
DTEND;TZID=Europe/Stockholm:20241218T120000
DTSTAMP:20260421T173342
CREATED:20240919T091627Z
LAST-MODIFIED:20240926T111715Z
UID:10001361-1734519600-1734523200@www.scilifelab.se
SUMMARY:IP Strategies for Academic Startups\, Pharma and Biotech Companies in the Life Sciences
DESCRIPTION:Welcome to this Drug Discovery Webinar\, organized by OligoNova and SciLifeLab Drug Discovery and Development. \n\n\n\nThis seminar will build on the previous sessions on regulatory protection and trade secrets\, aiming to provide real world examples of how these approaches can be used to drive the growth of start-ups. Come with your questions and experiences to share! \n\n\n\nregistration\n\n\n\nAgenda \n\n\n\n\nIntroduction – Fredrik Wångsell\, OligoNova\n\n\n\nIP Strategies in the Life Sciences – Fiona Hey\, Tony Proctor and Michel Pears Potter Clarkson\n\n\n\nBio-tech start-up/company that used trade secrets successfully (to be announced)\n\n\n\nInput from your own experiences\n\n\n\nDiscussion\n\n\n\nQ&A\n\n\n\n\nWelcome \n\n\n\nSciLifeLab DDD and OligoNova \n\n\n\nOther Seminars\n\n\n\nOligaNova organizes three seminars during the fall 2024 \n\n\n\nTrade secrets in the Life Sciences\, October 15 \n\n\n\nMaximizing exclusivity in the Life Sciences\, November 6 \n\n\n\nIP Strategies in the Life Sciences\, December 18
URL:https://www.scilifelab.se/event/ip-strategies-in-the-life-sciences/
LOCATION:Online event via Zoom
CATEGORIES:Event
ORGANIZER;CN="OligoNova - Part of the Drug Discovery and Development Platform":MAILTO:par.matsson@oligonova.org
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BEGIN:VEVENT
DTSTART;TZID=Europe/Stockholm:20241220T110000
DTEND;TZID=Europe/Stockholm:20241220T120000
DTSTAMP:20260421T173342
CREATED:20241203T154235Z
LAST-MODIFIED:20241218T134310Z
UID:10001414-1734692400-1734696000@www.scilifelab.se
SUMMARY:Cancelled: My health\, my data - Privacy-preserving AI in systems medicine
DESCRIPTION:Dec 19:This event is unfortunately cancelled. \n\n\n\n\n\n\n\n \n\n\n\nProf. Jan Baumbach\, Computational Systems Biology\, University of Hamburg \n\n\n\nAbstract \n\n\n\nEuropean Health Data Spaces\, national digital health records archives and similar initiatives aim to provide a mixture of legal and technical frameworks to make privacy-sensitive medical data available for data mining. The ultimate goal is to access the yet behind legal barriers hidden healthcare data treasure in order to train prognostic models for personalized medicine – from disease management to individualized drug repurposing prediction. The biggest road block is the GDPR. In the talk\, we will discuss federated learning technology that – coupled to other privacy-enhancing technologies – allows for a secure multi-center data mining collaboration. Specifically\, we will demonstrate that it does provide as accurate results as centralized solutions. We will discuss concrete applications for multi-centric genome-wide association studies\, for meta-genomics\, transcriptomics and proteomics analysis including batch effect correction\, and for survival time analysis. One applications involved >1\,000 hospitals in North America\, another one involves >100\,000 European screening participants. Finally\, we discuss the limitations and future prospects of federated learning in biomedicine and healthcare data mining.
URL:https://www.scilifelab.se/event/my-health-my-data-privacy-preserving-ai-in-systems-medicine/
LOCATION:Air&Fire\, SciLifeLab Stockholm\, Tomtebodavägen 23A\, Solna\, Sweden
CATEGORIES:Event
END:VEVENT
END:VCALENDAR