SciLifeLab

Stockholm Single Cell and Spatial Genomics Symposium 2026
2026-04-20 09:00 - 17:30 (Europe/Stockholm) | IVA Conference center, Grev Turegatan 16, Stockholm
The Stockholm Single Cell and Spatial Genomics Symposium 2026 is a national meeting dedicated to advancing single-cell and spatial genomics technologies and their application in basic, applied, and translational research.

Building on the success of the 2024 symposium, this full-day event will once again bring together leading Swedish and international researchers, technology developers, and industry partners. The program will feature keynote lectures, scientific talks, technology showcases, and ample networking opportunities, with a strong focus on state-of-the-art methods and innovative applications.

Registration

This event is currently fully booked

By fostering knowledge exchange and community building, the symposium aims to accelerate the adoption of single-cell and spatial genomics approaches across Sweden and further strengthen the national research ecosystem supported by SciLifeLab and NGI.

Organizers

National Genomics Infrastructure

National Genomics Infrastructure (NGI)

In Situ Sequencing

In Situ Sequencing

Program

Agenda.SCSG_2026 (1)Download

The Global Open Research Commons International Model: A path towards greater interoperability for digital research infrastructures
2026-04-21 11:00 - 12:00 | Online event via Zoom
The Global Open Research Commons (GORC) International Model (starting with its Essential Elements) has been in development since 2016 within Research Data Alliance Interest and Working Groups. It is now a mature way to guide implementation decisions, a framework for new commons implementers, and a shared language for interoperability discussions. This talk will provide an overview of the GORC approach, its current uptake, and its future plans. It should be of interest to anyone concerned with interoperability within and between DRI.Presenter: Andrew Treloar (PhD), DRI Consultant

This event is part of the SciLifeLab Open Science seminar series, an event series by the SciLifeLab Data Centre and NBIS joint Data Management team.The goal of the events in this seminar series is to provide interesting interactive seminars around topics related to Research Data Management and Open Science in general, and to foster discussions around best practices. More information about SciLifeLab Data Centre and NBIS joint Open Science seminar series: https://www.scilifelab.se/data/scilifelab-data-management-seminar-series/ If you have suggestions for topics or presentations, please contact us at data-management@scilifelab.se For more information or inquiries, please contact us at data-management@scilifelab.se

More Information

This event is part of the SciLifeLab Open Science seminar series, an event series by the SciLifeLab Data Centre and NBIS joint Data Management team.The goal of the events in this seminar series is to provide interesting interactive seminars around topics related to Research Data Management and Open Science in general, and to foster discussions around best practices.

Research Data Management (RDM) concerns the organization, storage, preservation, and sharing of data that is collected and analyzed during a research project. Proper planning and management of research data will make project management easier and more efficient while projects are being performed. It also facilitates sharing and allows others to validate as well as reuse the data.Open Science is a set of principles and practices that aim to make scientific research from all fields accessible to everyone for the benefits of scientists and society as a whole. Open science is about making sure not only that scientific knowledge is accessible but also that the production of that knowledge itself is inclusive, equitable and sustainable.

The events are open to everyone working at or affiliated with a Swedish research institute or university. We welcome all researchers, educational professionals, staff, RDM professionals, and others with an interest in life sciences, from all university levels. The events are informal and inclusive, so feel welcome to join and participate in our interesting discussions!

The events will be recorded and published openly after the seminars on the SciLifeLab YouTube channel. The slides will be made available at our SciLifeLab Data Repository.More information about SciLifeLab Data Centre and NBIS joint Open Science seminar series: https://www.scilifelab.se/data/scilifelab-data-management-seminar-series/

If you have suggestions for topics or presentations, please contact us at data-management@scilifelab.seFor more information or inquiries, please contact us at data-management@scilifelab.se

Digital Townhall meeting about the Beta building of Campus Solna
2026-04-22 14:00 - 16:00 | Online event via Zoom
Welcome to a townhall meeting for the SciLifeLab community to hear more about the plans of Campus Solna expansion to include the Beta building, and to learn what this means for SciLifeLab from a national perspective.

Agenda

The national perspective on Campus Solna expansion – what does this mean for SciLifeLab? Jan Ellenberg, SciLifeLab Director

The Beta project, Per Ljungdahl, Campus Solna Director

Q&A session

After the digital meeting, all community members present at Campus Solna on April 22nd are most welcome to join the continued dialogue about the Beta project in the Delta area/lobby. Refreshments will be served.

Register here

Campus Solna Seminar Series: Baizhen Chen & Yue Chen
2026-04-23 12:00 - 13:00 | Milkyway SciLifeLab Solna, Tomtebodavägen 23, Solna
Welcome to join the Campus Solna Seminar Series – an initiative to promote the fantastic science ongoing at Campus Solna and hopefully forge more internal communication and collaboration between within Campus Solna. The format consists of two 20 min talks (One speaker from the Alpha-building and one from the Gamma-building respectively), with an additional 5 min of questions. Presentation of ongoing (unpublished) projects is strongly encouraged.

The seminars are held Thursdays 12:00-13:00. You can bring your lunch to the seminar.

PhD students that are attending the Campus Solna Seminar lectures will have the opportunity to gain credits. For the syllabus and instructions on how to obtain these credits, read this document. Please contact your own department at your host University to confirm.See here the full schedule for this semester.

This week:

Baizhen Chen

Cecilia Williams – alpha

Yue Chen

Lucie Delemotte – gamma 3

This seminar series is organized by the PhD & Postdoc Council. For more information about the Council and other events check our page.

CSI Seminar - Assertive Communication and Boundary Setting
2026-04-23 15:00 - 15:30 | Gamma 2 Lunchroom, SciLifeLab, Tomtebodavägen 23, Solna, Sweden
Academic environments thrive on the exchange of ideas through collaboration — yet the way we communicate profoundly shapes collegial relationships. From daily interactions and departmental dynamics to supervision, workload expectations, and difficult conversations, healthy communication — including the ability to set clear, professional boundaries — is an essential skill.In this seminar, we will explore how to communicate with clarity, confidence, and respect — even in high-pressure situations. We will examine assertive communication and how it can meet passive, aggressive, and passive-aggressive communication styles in academic culture. We will discuss practical strategies for fostering healthy communication within research teams, navigating challenging moments that could escalate into conflict, and recognizing when a boundary is needed — along with how to set one constructively. This seminar offers actionable tools to strengthen professional relationships, negotiate workload demands, and contribute to a more respectful and collaborative academic environment.

We will begin with a ~ 20 min talk, held in Solna and over zoom. Then proceed with a reflection and discussion held on-site. We encourage other sites to form watch parties, by listening in together to the talk and then hold their own discussion afterwards. Hopefully seeding many local chapters of CSI.

To help facilitate discussion and reflection, consider the following starter questions:

Awareness: where do we experience rejection in our lives already?

Analysis: how well do I currently interact with rejection?

Alternative: how could we relate to rejection in academia, for ourselves and others?

Action: how will knowledge of rejection in academia change my decisions going forward?

Clinical and translational analyses in the neoadjuvant PREDIX trials in breast cancer
2026-04-24 09:00 - 10:00 | Online event via Zoom
Speaker

Theodoros Foukakis, Karolinska Institutet

Abstract

The PREDIX trials are academic, randomised phase 2 studies of neoadjuvant therapy in breast cancer, coordinated by Karolinska. Patients with luminal breast cancer were randomised to either chemotherapy or endocrine therapy in combination with palbociclib. Patients with HER2-positive disease received preoperatively either a standard of care combination of chemotherapy and HER2-targeting antibodies or the antibody-drug conjugate trastuzumab-emtansine. Both trials had a translational focus with serial biopsies and blood samples collected at baseline and during treatment. A comprehensive multimodal profiling of the tumours has been carried out, and the molecular profiles of the tumours have been correlated to the clinical outcomes. The initial results from these studies will be presented.

Short biography

Theodoros Foukakis, MD, PhD, is Professor of Oncology at Karolinska Institutet and a senior attending physician and scientific head for breast cancer at the Comprehensive Cancer Centre, Karolinska University Hospital, Stockholm, Sweden. He is head of the national guidelines group for breast cancer in Sweden, a member of the Swedish Breast Cancer Group (SweBCG), and a steering committee member of The Early Breast Cancer Trialists’ Collaborative Group (EBCTCG).

Dr Foukakis completed his medical studies at the University of Crete, Greece, in 2002 and moved to Stockholm, Sweden, where he pursued a PhD in cancer genetics at Karolinska Institutet. Subsequently, he undertook clinical training in Oncology at Karolinska University Hospital between 2005 and 2009 and has since worked as a specialist, combining clinical work with research, with a focus on breast cancer.

He has led several investigator-initiated trials sponsored by Karolinska University Hospital and served as national principal investigator for many industry-sponsored trials from phase 1 to phase 3.

He leads a research group of 22 members and has secured independent funding through national or international competitions over the last 10 years. His group is particularly interested in drug and biomarker development in breast cancer with a focus on multi-omics analyses and machine learning.

About Clinical Talk:

After seven successful seasons and over seventy dedicated speakers, we are excited to continue showcasing the contributions of our diverse clinical, academic, and industry life science community. This season will feature ten insightful talks following our well-established format.

The overarching theme is “How to Achieve Feasible Implementation.” Sessions will be held monthly on Fridays from 09:00 a.m. to 10:00 a.m. via Zoom, with occasional exceptions. Each talk will be followed by an engaging Q&A session, moderated by the standing host, Rikard Fred, and a guest moderator with subject-matter expertise to enrich the discussion.

In today’s post-pandemic world, let’s explore how academic, clinical, and industry research, together with technological advances, can drive practical, sustainable solutions. Join us for an opportunity to gain fresh insights, expand your knowledge, and connect with experts shaping the future of life sciences!

Clinical talks are organised by SciLifeLab.

[The Svedberg seminar] - Tracking the chemical basis of toxicological responses: from genome-wide mapping of DNA modifications to quantitative chemical activity profiling of gut microbiome modulations
2026-04-27 15:15 - 16:15 | BMC Room C8:305
Shana J. Sturla

ProfessorETH Zürich, Switzerland

Bio

Shana J. Sturla is Full Professor of Toxicology at the ETH Zurich, the Swiss Federal Institute of Technology.Professor Sturla was born in New York, USA and studied Chemistry at the University of California at Berkeley and the Massachusetts Institute of Technology. She carried out a postdoctoral fellowship in Toxicology with Professor Stephen S. Hecht at the University of Minnesota Cancer Center, where her research concerned tobacco carcinogenesis and cancer chemoprevention with dietary compounds.

In 2004, Shana became an Assistant Professor at the University of Minnesota. Her work there was recognized with an NIH Career Development Award and, as a Dominican American, she received an American Association for Cancer Research Minority Scholar in Cancer Research Award. In 2009, she joined the faculty of the ETH Zurich, as Associate Professor with tenure and in 2016 was promoted to Full Professor.

She leads the Laboratory of Toxicology at the ETH Zurich. The goal of her research is to promote chemical, food and drug safety by elucidating the chemical basis of mutagenesis and toxicity, and to promote innovative bioanalysis strategies for predicting chemical hazards on the basis of chemical structures and reactivity, molecular responses and in vitro testing. Key areas of research interest include the study of environmental toxicants related to human disease, DNA damage and mutagenesis, drug resistance in cancer therapy and biotransformation of xenobiotics by human gut microbiota.

She teaches various courses at the ETH including Introduction to Toxicology, Biological Chemistry (Nucleic Acids), Molecular Disease Mechanisms (Cancer Section), a Laboratory Course in Toxicology, and the Carcinogenesis module for the Swiss Masters of Advanced Study in Toxicology.

Shana is the President of the Swiss Society of Toxicology, Member of the Platform Chemistry of the Swiss Academies of Science, and Editor-In-Chief of Chemical Research in Toxicology.

Her website is www.toxicology.ethz.ch.

Tracking the chemical basis of toxicological responses: from genome-wide mapping of DNA modifications to quantitative chemical activity profiling of gut microbiome modulations

Understanding how chemical exposures translate into biological outcomes requires a multi-scale approach that bridges molecular interactions with systemic shifts in homeostasis. The Laboratory of Toxicology at the ETH Zürich develops high resolution strategies for tracking chemically induced alterations in cells by examining two critical interfaces: the human genome and the gut microbiome. In this talk, I will introduce chemical biology strategies for the high-resolution mapping of discrete DNA modifications, including drug-induced alkylation, strand breakage, and base oxidation. Using tailored sequencing approaches such as click-code-seq, we demonstrate how the frequency and persistence of these lesions across the genome serve as diagnostic indicators of mutagenesis, biological aging, and disease susceptibility. Second, we use chemical activity profiling to quantify the functional biotransformation capacity of the gut microbiota. By measuring degradation rates of metabolic probes, and chemicals relevant to human exposures, we reveal how exposure to xenobiotics significantly modulates the function of gut microbiomes and vice versa. By examining chemical signatures in both the host genome and the microbiota, we can more precisely define the drivers of biological dysfunction as a basis to elucidate mechanisms of genome instability and host–microbiome interactions.

Host: Daniel Globisch daniel.globisch@scilifelab.uu.se

Minisymposium on Cell State Transitions in Stress and Disease
2026-04-28 13:00 - 15:00 | Air&Fire, SciLifeLab Stockholm, Tomtebodavägen 23A, Solna, Sweden
Program

13:00 – 13:30 Assoc. Prof. Peter Svensson (KI)

13:30 – 14:00 Assoc. Prof. Laura Baranello (KI)

14:00 – 14:30 Prof. Lea Sistonen (Åbo Akademi Univ. Finland)

14:30 – 15:00 Assist. Prof. Anniina Vihervaara (KTH)

Brief break with Fika

15:15 – 16:15 Spotlight seminar, Valerie Mezger

Stress-responsive pathways in pathophysiological prenatal brain development

host: Anniina Vihervaara anniina.vihervaara@scilifelab.se

Stress-responsive pathways in pathophysiological prenatal brain development
2026-04-28 15:15 - 16:15 | Air&Fire, SciLifeLab Stockholm, Tomtebodavägen 23A, Solna, Sweden
Professor Valérie Mezger, Université de Paris

Abstract

The Development and Environment Interface team led by Valérie Mezger studies the impact of stress on cell identity. We aim to understand how prenatal stress perturbs neural cell fate and therefore contributes to neurodevelopmental disorders (NDDs) through transcriptomic and epigenetic components of stress responses to shape normal and pathological neurodevelopment. For this, we focus on stressors of prenatal relevance (prenatal alcohol exposure or neuroinflammation, induced by infections), which are major causes of non-genetic NDDs and, for genetic NDDs, combine the use of mouse models and human cerebral organoids to single-cell multi-omics approaches. The team demonstrated that deregulation of stress-responses is also observed in monogenic NDDs and therefore have developed a transfer project and collaborations with mathematicians in deep learning to build therapeutic strategies.

Biography

After her cursus in the École Normale Supérieure (ENS Paris, France), VM completed her PhD in Molecular and Cellular Biology (Université Pierre et Marie Curie, Paris 6) at the Pasteur Institute, in the François Jacob Lab, under the supervision of Olivier Bensaude and Michel Morange. She obtained a permanent position in the CNRS, based on her unravelling of key, physiological, activation of the stress-responsive Heat Shock transcription Factors (HSFs) in normal (unstressed) early embryonic development. For her postdoc, she joined the laboratory of Uri Nudel and David Yaffe in the Weizmann Institute (Israel), on the cerebral role of the Duchenne Muscular Dystrophy gene. VM then developed her own group in the Morange Lab in the ENS, and uncovered the role of HSF2 in normal brain development. Since 2009, she has been leading the Interface between Development and Environment Team, one of the six founding groups of the Center of Epigenetics and Cell Fate (CNRS), created at the new campus (PRG) of Université Paris Diderot (now Université Paris Cité). She co-directed this Centre as Deputy Director (2009-2018; Director, Jonathan Weitzman) and then directed (2019-2024; Deputy Director, Claire Rougeulle). She has had a long-term collaboration with the Lea Sistonen laboratory (Åbo/Turku University, Finland) and Pierre Gressens (Hôpital Robert Debré, NeuroDiderot, INSERM, Paris). She collaborates with Auguste Genovesio laboratory (iBENS, Institut de Biologie, ENS, Paris) for the development of deep learning solutions to distinguish subtle phenotypes from biological variability intrinsic to complex biological objects, like organoids. VM is also a coleader of the preclinical program of the IHU Robert Debré du Cerveau de l’Enfant (ICE; Hospital-University Institute of the Child Brain, Paris).

Host: Anniina Vihervaara anniina.vihervaara@scilifelab.se

Umeå seminar series:"AlphaFold in an HPC environment"
2026-04-29 12:00 - 13:00 | Glasburen Seminar Room, Chemical Biological Centre (KBC) Building, Umeå University, Umeå, 901 87, Sweden
“AlphaFold in an HPC environment”Presenter: Pedro Ojeda May, Application expert, Staff scientist at High Performance Computing Centre North (HPC2N), Umeå University

We will begin with a brief introduction to AlphaFold, followed by an overview of related software for protein structure prediction.Because these simulations are computationally demanding on a standard PC, we will present a workflow for running them on a High Performance Computing (HPC) cluster, illustrated through several demonstrations. Learn more about HPC2N: https://www.hpc2n.umu.se/

Registration: Sign up for the IRL seminar and reserve your free lunch by Monday, 27 April, 10:00, or follow online (registration is not required):

Register

SciLifeLab Site Umeå/KBC Infrastructure Seminar Series

This event is part of the SciLifeLab site Umeå/KBC Infrastructure Seminar series, for future events in spring 2025, check the seminar series home page.

Take me there
