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SciLifeLab The Svedberg seminar series: Adam Abate, Quantitative biology with droplet microfluidics

Monday September 30 at 15:15

 Adam Abate

UCSF, San Francisco, USA

Adam Abate is an Associate Professor at the University of California, San Francisco in the Department of Bioengineering and Therapeutic Sciences (BTS) in the Schools of Medicine and Pharmacy. He is in QB3 and part of the UC Berkeley-UCSF Graduate Program in Bioengineering, PSPG, and iPQB. His research interests are in high-throughput biology with microfluidics, protein engineering through directed evolution, and biophysics.

Title of the talk: Quantitative biology with droplet microfluidics

Many questions at the forefront of biology depend on the interactions of millions of single cells. My lab develops technologies for studying large numbers of single cells. In this talk, I will describe our approaches for sorting cells based on genomic and transcriptomic markers, and performing multi-omics analysis of single cells that allow simultaneous characterization of genomic, transcriptomic, and proteomic signatures. I will also describe how we are adapting these techniques to integrate genomics with other single cell measurement approaches, including imaging, mass spectrometry, and atomic force microscopy. Finally, I will describe how we are using these techniques to build cells into controlled consortia for microbiological studies and bottom-up tissue synthesis.

Host: Ioana Onut Brännström