Workshop: Atomic Force Microscopy in Life Science


Lecture hall Air/Fire, ground floor, SciLifeLab, Tomtebodavägen 23A, Solna

This workshop covers the latest developments in Atomic Force Microscopy (AFM) for life science applications with experts in the field from academia and instrument providers. The use of mechanical force to characterize cells and molecules over dimensions of 1 nm to 10’s of μm provides unique information on structure and function. Apart from providing high-resolution and exceptionally high contrast 3-D surface maps down to atomic resolution (in the best cases), AFM also provides a sensitive tool to measure for example cell stiffness and adhesion,properties that are important in both normal and pathological conditions (such as cancer). The workshop is organized by the Bioimaging platform together with Departments of Applied Physics, KTH, and Department of Microbiology, Tumor and Cell Biology (MTC), Karolinska Institutet.

Program:
9.00-12.30 AFM in Life Science Presentations

Speakers & Topics:
Dr. Marija Plodinec, University of Basel – Cell mechanics
Dr. Ludmilla Morozova-Roche, Umeå Univerisity – Amyloid imaging
Dr. Jan Hoh, Johns Hopkins and KTH – Characterizing protein patterned surfaces
Dr. Alessandro Bosco, Karolinska Institute – Cell adhesion
Dr. Cvetelin Vasilev, University of Sheffield – Membrane protein imaging

14.00-18.00 Demonstrations. See application experts from the instrument providers perform measurements.

Topic 1: 14.00-16.00 – Cell mechanics (cell stiffness and adhesion)
Topic 2: 16.00-18.00 – High resolution imaging of DNA and/or amyloid peptides
(Held at the Nanofabrication laboratory at AlbaNova University Center, Roslagstullsvägen 30, Stockholm.)

Registration:
Please register by e-mail to Matthew Fielden, fielden@kth.se. Please indicate which
parts of the workshop you would like to attend. There is limited capacity for the demonstrations – first
come first served!