CRISPR’s twist of fate: Unmasking unintended genomic deletions and their impact on cancer research
A team of SciLifeLab researchers has found an unforeseen 283-kb deletion on Chromosome 10 (10q23.31) in leukemia cells (HAP1), which increases during the generation of CRISPR-Cas9–modified cells, e.g., in CRISPR … Continue reading CRISPR’s twist of fate: Unmasking unintended genomic deletions and their impact on cancer research
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