Press - 2012
A step towards more efficient spruce breeding programs
Conifers normally go through a long juvenile period, for Norway spruce (Picea abies) around 20-25 years, before developing cones. This is a major obstacle for spruce breeding efforts. Researchers at Science for Life Laboratory – Stockholm in collaboration with colleagues at SLU (Uppsala) and Skogforsk have now managed to produce a spruce variety that can be made to set cones one year after planting. The spruce variety originates from a spruce mutant that was found outside of Uppsala more than 100 years ago. By using the next generation sequencing facility at Science for Life Laboratory coupled with advanced bioinformatics and molecular biology methods the researchers have identified a possible regulator of the early cone setting. The cone inducing properties of the early cone setting spruce will be used to enhance future breeding programs of Norway spruce.
Three SciLifeLab Directors appointed to Wallenberg Scholars
[PRESS RELEASE 2012-12-11] Knut and Alice Wallenberg Foundation (KAW) has appointed 16 distinguished researchers the Wallenberg Scholars. Three of the researchers selected are Directors at Science for Life Laboratory (SciLifeLab); Mathias Uhlén, professor in microbiology at the Royal Institute of Technology, Gunnar von Heijne, professor in theoretical chemistry at Stockholm University and Kerstin Lindblad-Toh, professor in comparative genomics at Uppsala University. Leif Andersson, professor in functional genomics at Uppsala University and part of the SciLifeLab Uppsala Program Board also received the Wallenberg Scholars 2013. Each Wallenberg Scholar receives a five-year research grant of 3 MSEK per year.
SciLifeLab/KI team finalists in Boston Children’s Hospital’s competition
[PRESS RELEASE 2012-11-08] Science for Life Laboratory (SciLifeLab) and Karolinska Institutet (KI) were among the top eight teams in the Boston Children’s Hospital’s CLARITY challenge. The team got an honorable special mention as one of eight finalist teams, who managed to solve two out of three genetic mutations in the cases of three children that suffer from disorders with unknown genetic cause. The team also suggested appropriate follow up tests for the third case.
Microscope expert at SciLifeLab wins Lennart Nilsson Award
[PRESS RELEASE 22 October 2012] Hans Blom PhD, associate professor of biological physics at the Royal Institute of Technology (KTH) and facility manager at the Science for Life Laboratory in Stockholm, is to receive SEK 100,000 for studying and evaluating the nanoSIMS and STORM microscope techniques at Harvard University, Boston USA.
SciLifeLab researcher awarded SEK 16.6 million from KAW to study the brain
[PRESS RELEASE 2012-10-05] Joakim Lundeberg and colleagues Jonas Frisén and Patrik Ståhl have been granted SEK 16.6 million from the Knut and Alice Wallenberg Foundation to study the brain. They have developed a new method that combines gene expression data from sequencing and tissue localization from microscope imaging. By this method Joakim Lundeberg at the Royal Institute of Technology and Jonas Frisén and Patrik Ståhl at Karolinska Institutet will perform a complete mapping of which genes in the brain that are active and where in the tissue they are expressed.
Version 10.0 release of the Human Protein Atlas
Today the latest version of the Human Protein Atlas was released. This version covers approximately 70% of the human genome and includes a Dictionary.
SciLifeLab welcomes new funding from the Swedish government
Yesterday the Swedish government presented the contents of the upcoming research and innovation bill, which includes a special investment in the life science area. Among other things, SciLifeLab gets a yearly addition of SEK 200 million.
Single mutation affects gaits in horses
Researchers at Uppsala University, the Swedish University of Agricultural Sciences and their international collaborators have discovered a mutation in a single gene in horses that is critical for the ability to perform ambling gaits, for pacing and that has a major effect on performance in harness racing.
Novel regulators of brain development found
[PRESS RELEASE 2012-06-12] By combining high throughput sequencing, bioinformatics and specific experimental verifications, groups at Stockholm University, Science for Life Laboratory and the Royal Institute of Technology, have shed light on the impact that specific nucleotide base changing, so-called A-to-I RNA editing, of particular small RNA structures has on regulatory non-coding RNA during brain development
Gunnar von Heijne awarded the ISCB Accomplishment by a Senior Scientist Award
[PRESS RELEASE 2012-06-05] Gunnar von Heijne has been awarded the International Society for Computational Biology (ISCB) Accomplishment by a Senior Scientist Award. Gunnar von Heijne runs the Centre for Biomembrane Research in Stockholm, leads the group Membrane protein assembly and structure at Stockholm University and is Vice Director of the Science for Life Laboratory Stockholm.
Novel tumor proteomics strategy discriminates patient sub-groups in HPV related gynecological cancer
[PRESS RELEASE 2012-05-10] A novel strategy to analyze tumor proteomics data was employed by researchers at the Karolinska Institutet and Science for Life Laboratory to increase the understanding of molecular pathways in the gynecological cancer vulvar squamous cell carcinoma and how patient sub-groups that do or do not relapse regardless of infection with human papilloma virus (HPV) can be discriminated.
Three-spined stickleback’s genes show adaptation to fresh water
The genome of the three-spined stickleback has now been mapped by an international research group led by researchers at Uppsala University and Broad Institute and Stanford University in the US. The results are published in the scientific journal Nature and show how the genes changed to enable the three-spined stickleback to adapt to fresh water after the last ice age. Most of the changes took place through mutations in the regulation of genes.
Historic investment in SciLifeLab welcomed
[Press release 2012-04-03] The presidents of the four Swedish universities behind the Science for Life Laboratory (SciLifeLab) welcome the huge new investments in life science research announced today.
Improved proteomics tools generated in multidisciplinary EU consortium
[PRESS RELEASE 2012-04-02] New and optimized technological approaches are developed within the PROSPECTS project taking part in moving the proteomics field beyond the large-scale detection and analysis of proteins towards performing true quantitative measurements and to follow cells response to stress or drugs at a proteome-wide level.
SciLifeLab Uppsala gets news premises in Uppsala
Uppsala University and Akademiska Hus are jointly investing SEK 177 million in expanding the Uppsala Biomedical Center (BMC). The goal is to provide medical and molecular bioscience researchers at the Science for Life Laboratory (SciLifeLab) with a meeting place of international stature.