I am a member of the EMBLA research group, which develops miniaturised systems for biomedical and life science applications. Within the group, I lead the biomaterials-on-chip research line. The rationale for this new line of research lies in the great promise of biomaterials, namely bioceramics, for bone generation that leaves no trace behind. However, before a newly designed bioceramic can be released to the market, its biological properties must be vigorously evaluated both in the lab using cells (in vitro) and in animal models (in vivo). The main challenge with this is that in vitro tests show a poor correlation with in vivo studies. There is therefore a need for a more reliable methodology to evaluate the biological properties of biomaterials in vitro.
My research aims to develop microfabricated devices to evaluate the biological properties of biomaterials in a more realistic manner and provide real-time results. These microfluidic devices will represent a reliable and efficient screening platform of the biological properties of bioceramics, making the path from lab to society both shorter and safer.
Gemma Mestres, Assoc. Prof.
Sarah-Sophia Carter, PhD Student
Abdul Raouf Atif, MSc student
Sajal Tiwari, MSc student
Telephone: 018-471 6805
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