We study how development of blood cells (hemocyte) is regulated at the molecular level, and further examine relationships between the hematopoietic tissue and the neuronal precursor lineage that produces adult-born neurons in the brain of freshwater crayfish. We have discovered a group of cytokines, astakines, involved in both these processes and now focus on: 1) finding specific markers for hematopoietic and neurogenic precursor cells 2) how astakines affects stem cells to become mature hemocytes and 3) how the hematopoietic system and adult neurogenesis are coordinately regulated. We hope to get increased knowledge about the regulation of hematopoiesis, neurogenesis and the evolution of cytokines.
Irene Söderhäll, PhD, professor
Charlotta Ekblom, PhD student
Ariadne Hernández-Pérez, PhD, postdoc
Kingkamon Junkunlo, PhD, postdoc
Ratchanok Sirikharin, PhD, researcher
Kenneth Söderhäll, PhD, senior professor
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