PhD student in Environmental Science focusing on Environmental Toxicology and Epigenetics

Published: 2018-03-09


Project description
The PhD student position will be associated with projects concerning environmental toxicology and epigenetic mechanisms. There has been a rapidly increasing interest in whether environmental factors modulate the establishment and maintenance of epigenetic modifications, and thereby affect gene expression and phenotype in humans and wildlife. Chemical pollutants, dietary components, temperature changes and other external stressors can indeed have long-lasting effects on development, metabolism and health, and maybe even in subsequent generations. Although the underlying mechanisms remain largely unknown, particularly in humans, mechanistic insights are emerging from experimental model systems, which may have implications for understanding disease and development. We aim to combine experimental and epidemiological research to study gene-environment-epigenome interactions. In particular, our research focuses on developmental origins of health and disease with an emphasis on environmental exposures and epigenetic mechanisms (DNA methylation and noncoding RNA). The projects concern the effects of environmental exposures such as endocrine disrupting chemicals, flame retardants, pesticides, metals, particulate air pollution, as well as drugs, psycho-social stressors and ethnical disparities. Ongoing efforts include investigation of multigenerational epigenetic inheritance.

 

Qualification requirements
To meet the general entry requirements, the applicant must have completed a second-cycle degree, completed courses equivalent to at least 240 higher education credits, of which 60 credits must be in the second cycle, or have otherwise acquired equivalent knowledge in Sweden or elsewhere.

In order to meet the specific entry requirements, for doctoral studies in Environmental Science, at least 45 of the credits at the second cycle must be in one of the natural sciences (Biology, Chemistry, Earth Sciences, Physics, or Meteorology) including a 30 hp/HEC thesis project. The applicant should also have 30 hp/HEC in other natural science subjects different from the major. The applicant may also have MSc degree in other relevant areas (e.g. Toxicology, Pharmacy, Biomedicine, or Molecular biology).

The qualification requirements must be met by the deadline for applications.

 

Terms of employment
Only a person who will be or has already been admitted to a third-cycle programme may be appointed to a doctoral studentship. The term of the initial contract may not exceed one year. The employment may be extended for a maximum of two years at a time. However, the total period of employment may not exceed the equivalent of four years of full-time study. Doctoral students should primarily devote themselves to their own education, but may engage in teaching, research, and administration corresponding to a maximum of 20 % of a full-time position.

 

Contact
For more information, please contact Associate Professor Oskar Karlsson, oskar.karlsson@farmbio.uu.se.

 

Application
Apply for the PhD student position at Stockholm University’s recruitment system.

Please include the following information with your application

  • Your contact details and personal data
  • Your highest degree
  • Your language skills
  • Contact details for 2–3 references

and, in addition, please include the following documents

  • Cover letter
  • CV – degrees and other completed courses, work experience and a list of degree projects/theses
  • Degree certificates and grades confirming that you meet the general and specific entry requirements (no more than 6 files)
  • Letters of recommendation (no more than 6 files)
  • Degree projects/theses (no more than 6 files).