Postdoctoral researcher in Single-Molecule Studies of Chromatin Complexes


The Deindl lab (www.deindl-lab.com) is an international and ambitious research team that provides a stimulating and friendly environment for hard-working scientists with a genuine interest in tackling important biological questions. We have recently been awarded an ERC starting grant to investigate the molecular mechanisms of protein machines using a highly multidisciplinary approach that combines state-of-the-art single-molecule fluorescence imaging (see for example, Deindl et al., Cell 2013 or Hwang*, Deindl*, et al., Nature 2014) with a range of biophysical, structural, and biochemical techniques. We are located at the SciLifeLab and the Department of Cell and Molecular Biology (ICM) at Uppsala University, one of the most international, interdisciplinary and successful research departments in molecular biosciences in Europe.

Job description
The starting date for the position is as soon as possible or per agreement. The position is initially for one year but offers a longer-term perspective.

We are seeking a highly motivated postdoctoral researcher to carry out biophysical studies into the mechanisms of chromatin-associated complexes using single-molecule imaging approaches along with complementary biophysical and biochemical techniques. Several exciting projects are available and can be tailored to individual interests and expertise. The researcher will benefit from a custom-built state-of-the-art two- and three-color single-molecule FRET microscope, excellent resources, infrastructure, and support as well as collaborators who are international leaders in their fields.

Qualifications
Applicants should possess a PhD in the life sciences, biophysics or physics, bioengineering, physical chemistry, or a related discipline that the group leader considers suitable. A strong background in single-molecule biophysics or advanced fluorescence microscopy would be advantageous but is not strictly required, as well as prior experience with wet-lab biochemistry. Good English language skills are essential. The ability to work in a team, good organizational skills as well as initiative, flexibility and good learning ability are required. Particular emphasis will be placed on personal suitability.

To apply
The application should be emailed to Assistant Professor Sebastian Deindl (sebastian.deindl@icm.uu.se) and be written in English, include a short letter of motivation detailing the applicant’s research interests and expertise, a CV, a copy of the university degree(s) and university entrance qualification with grades (e.g., baccalaureate, A-levels, Abitur, SAT score) and the contact information for at least two referees who can provide references.