The research by Lena Eliasson aims to understand the pathogenesis of diabetes. She investigates cellular mechanisms underlying impaired insulin- and glucagon-secretion from pancreatic islet β- and α-cells, respectively. The focus is on single cell physiology and molecular biology involving studies of ion-channels, exocytosis and miRNA-mRNA-protein networks important in the regulation of islet cell function.
Lena Eliasson
Lund University
Key Publications
Network-based insights into miRNA regulation of β-cell insulin secretion in type 2 diabetes
iScience, 2025
Single Fusion Pore Analysis via Single Cell Amperometry Uncovers Impaired Pore Expansion That Restricts Insulin Exocytosis in Human Type 2 Diabetes
Angewandte Chemie International Edition, 2025
HMGCR and rosuvastatin regulates GLP-1 secretion and expression – a translational study
The Journal of clinical endocrinology and metabolism, 2025
Single Fusion Pore Analysis via Single Cell Amperometry Uncovers Impaired Pore Expansion That Restricts Insulin Exocytosis in Human Type 2 Diabetes
Angewandte Chemie, 2025
Single-cell mRNA-regulation analysis reveals cell type-specific mechanisms of type 2 diabetes
Nature Communications, 2025