2018-02-19, NEWS

Human fatty liver disease eased by carbohydrate-restricted diet

Reduced carbohydrate intake result in fast and sizeable reductions of liver fat and other cardiometabolic risk factors in individuals suffering from obesity and fatty liver disease. This is shown in a new paper by Adil Mardinoglu (KTH/SciLifeLab) and colleagues, enabled by the SciLifeLab Clinical Biomarkers facility. In the ten patients subjected to a restricted diet […]

2018-02-14, NEWS

Self-sampling could double the detection rate of women with risk for cervical cancer

Using self-sampling followed by HPV-test, twice as many women with cervical intraepithelial neoplasia-positive (CIN2+) could be identified compared to Pap smear cytology. This is the conclusion from a study led by Ulf Gyllensten, Uppsala University/SciLifeLab, published in British Journal of Cancer. Read full press release by Uppsala University (in Swedish) Read full scientific paper

2018-02-12, NEWS

Janne Lehtiö new Scientific Director at SciLifeLab

Professor Janne Lehtiö has been elected Scientific Director of the SciLifeLab management group, representing Karolinska Institutet. Janne Lehtiö is a SciLifeLab faculty member, leads research in the field of medical proteomics and is affiliated with the Department of Oncology and Pathology at his host university. He is also the Facility Director of the Chemical Proteomics & Proteogenomics […]

2018-02-08, NEWS

Nordic Cryo-EM network established

The newly established network CryoNet aims at connecting experts in cryo-electron microscopy at the universities in Stockholm, Umeå, Århus and Copenhagen. Two of the microscopes that will be part of network are located at SciLifeLab in Solna. “This effort is a good reinforcement of the research environment around cryo-electron microscopy at SciLifeLab.” Said Gunnar von Heine (Stockholm […]

2018-02-06, NEWS

Release 4 of the FunCoup database of functional coupling networks

A new version of the FunCoup database ( has been released by a research team led by Erik Sonnhammer (Stockholm University/SciLifeLab). The database has been extended with networks inferred for six new species and for the first time also includes bacteria. To visualize subnetworks from queries, a new graphical network viewer is in place which […]

2018-02-06, NEWS

New technology for accelerated wound healing discovered

Researchers at Uppsala University and SLU led by Mia Phillipson, Uppsala University/SciLifeLab, have discovered a new way to speed up wound healing. The technology, published in PNAS, involves using lactic acid bacteria as vectors to produce and deliver a human chemokine on site in the wounds. “We have developed a drug candidate, a next-generation biologic […]

2018-02-05, NEWS

Heterogenous tumors increase risk of fatal breast cancer

Patients with estrogen receptor (ER)-positive disease have a long-term risk for fatal breast cancer, but he biological factors are unknown. To investigate whether high intratumor heterogeneity of ER is associated with this increased risk, users of the SciLifeLab Tissue Profiling facility studied the tumors of 1780 postmenopausal women and the patients’ survival rate. The results […]

2018-02-01, NEWS

SciLifeLab signs Memorandum of Understanding with European Lead Factory

The SciLifeLab Director and European Lead Factory executives have signed a Memorandum of Understanding for collaboration in future initiatives. SciLifeLab and the EU Lead Factory, a collaborative public-private partnership aiming to deliver innovative drug discovery starting points by e.g. giving free access to up to 500,000 novel compounds, declare to exploit the complementarity and synergistic […]

2018-01-31, NEWS

Maria Strömme speaker at event during World Economic Forum

On January 24, SciLifeLab faculty member and Professor of Nanotechnology Maria Strömme (Uppsala University) was one of the invited speakers at the Swedish Lunch arranged during World Economic Forum (WEF) in Davos, Switzerland. WEF annually brings together some of the world’s most powerful and influential decision makers in politics and business. Read more in a […]

2018-01-25, NEWS

Finding unknown parts of a well-known intracellular pathway

In a new study led by Tobias Sjöblom (Uppsala University/SciLifeLab), a large-scale search for genetic mutations in human colorectal cancer cells made it possible to assign additional genes to intracellular pathways of clinical importance for the disease. Around 60% of human colorectal cancers have mutations in the KRAS, BRAF or ERBB genes – all of which […]

2018-01-22, NEWS

Postnatal neurogenesis in region of hippocampus mapped on single-cell level

A new paper from the Sten Linnarsson group (Karolinska Institutet/SciLifeLab) reveals that murine neurogenesis in the hippocampus proceeds through distinct stages, from the first weeks after birth into adulthood. The dentate gyrus, part of the hippocampus, is involved in learning, episodic memory formation and spatial coding. It is known as a brain region in which […]