2019-01-15, NEWS

The Knut and Alice Wallenberg Foundation is investing over a 100 million SEK in research on tree genes, forest genetics and forest biotechnology. The project is a collaboration between SLU and SciLifeLab in Uppsala and Stockholm. The project focus on genomics and forest genetics and builds on a previous grant from the Knut and Alice […]

2019-01-14, NEWS

Primary human hepatocytes are used in all areas of liver research, from in vitro studies of toxicity to clinically managing liver failure. The availability of these hepatocytes is, however, limited due to the problem of cellular stress during isolation and cryopreservation, causing a highly unpredictable loss of the ability to attach and form cell-matrix and […]

2019-01-14, NEWS

While cancer-associated fibroblasts (CAFs) are known to be a major constituent of the tumor microenvironment, their origin and roles in shaping disease initiation, progression and treatment response have remained unclear due to significant heterogeneity. Now, a research team led by Kristian Pietras from Lund University has discovered three distinct subpopulations of the cancer-associated fibroblasts.   […]

2019-01-11, NEWS

Photo: Mari Kaunisto Professor and SciLifeLab Director Olli Kallioniemi is a winner of the 2019 Matti Äyräpää Award. This prize is the most important national medical prize in Finland, which has been awarded annually by the Medical Society Duodecim since 1969. Olli Kallioniemi is awarded for his pioneering contributions to molecular precision medicine, to new technologies and […]

2019-01-09, NEWS

DNA double-strand breaks (DSBs) jeopardize genome integrity and might give rise to structural rearrangements associated with cancer, when repaired unfaithfully. In a new study led by SciLifeLab researcher Nicola Crosetto (Karolinska Institutet), a research team delves deeper into the matter. While exogenous agents such as chemotherapy and ionizing radiation can invoke the DSBs, a large amount […]

2019-01-07, NEWS

A team of researchers at Karolinska Institutet and SciLifeLab have developed a new analysis method to map the localization of proteins in cells, information which they have shared in an open database accessible to researchers around the world. The study, published in Molecular Cell, was led by Professor Janne Lehtiö, SciLifeLab researcher and Facility Director for the SciLifeLab site of Chemical Proteomics & Proteogenomics.

2018-12-20, NEWS

Biotech company 10x genomics has announced their acquirement of Spatial Transcriptomics, an enterprise built around the technology with the same name and in large part developed at SciLifeLab. Spatial Transcriptomics is a method that allows visualization and quantitative analysis of the transcriptome in individual tissue sections, an approach providing data valuable for both research and […]