Johan Jakobsson

LINE-1 retrotransposons mediate cis-acting transcriptional control in human pluripotent stem cells and regulate early brain development. Adami A, Garza R, Gerdes P, Johansson PA, Dorazehi F, Koutounidou S, Castilla-Vallmanya L, Atacho DAM, Sharma Y, Johansson JG, Tam O, Kirkeby A, Barker RA, Hammell MG, Douse CH, Jakobsson J. Cell Genomics 2025 Aug 19:100979
https://www.sciencedirect.com/science/article/pii/S2666979X25002356
DOI: 10.1016/j.xgen.2025.100979

Mini-heterochromatin domains constrain the cis-regulatory impact of SVA transposons in human brain development and disease. Horváth V, Garza R, Jönsson ME, Johansson PA, Adami A, Christoforidou G, Karlsson O, Castilla-Vallmanya L, Koutounidou S, Gerdes P, Pandiloski N, Douse CH & Jakobsson J. Nature structural & molecular biology. 2024, 31(10):1543-1556
https://www.nature.com/articles/s41594-024-01320-8
DOI: 10.1038/s41594-024-01320-8

LINE-1 retrotransposons drive human neuronal transcriptome complexity and functional diversification. Garza R, Atacho DAM, Adami A, Gerdes P, Vinod M, Hsieh P, Karlsson O, Horvath V, Johansson PA, Pandiloski N, Matas-Fuentes J, Quaegebeur A, Kouli A, Sharma Y, Jönsson ME, Monni E, Englund E, Eichler EE, Gale Hammell M, Barker RA, Kokaia Z, Douse CH, Jakobsson J Science Advances. 2023, 9(44):eadh9543
https://www.science.org/doi/10.1126/sciadv.adh9543
DOI: 10.1126/sciadv.adh9543