Ylva Ivarsson

Uppsala university

Key Publications

1. Ivarsson, Y., Arnold, R., McLaughlin, M., Nim, S., Joshi, R., Ray, D., Liu, B., Teyra, J., Pawson, T., Moffat, J., Li, S.S., Sidhu, S.S. and Kim, P.M. (2014) Large-scale interaction profiling of PDZ domains through proteomic peptide-phage display using human and viral phage peptidomes. Proc Natl Acad Sci U S A 111: 2542-2547. The pioneering ProP-PD study showing that the approach can be used to find endogenous as well as host-virus interactions. # Citations 176.

2. Benz, C., Ali, M., Krystkowiak I., Simonetti, L., Sayadi, A., Mihalic, F., Kliche, J., Andersson, E., Jemth, P., Davey, N. E. and Ivarsson, Y. (2022) Proteome-scale mapping of binding sites in the unstructured regions of the human proteome. Mol Syst Biol 18: e10584. Fundamental paper outlining guidelines for SLiM-based interaction profiling, including how to analyze the results and how to assign confidence levels. Benchmarking of ProP-PD for large-scale interactomics. # Citations 82.

3. Mihalic, F., Simonetti, L., Giudice, G., Sander, M. R., Lindqvist, R., Akprioro Peters, M. B., Benz, C., Kassa, E., Badgujar, D., Inturi, R., Ali, M., Krystkowiak, I., Sayadi, A., Andersson, E., Aronsson, H., Söderberg, O., Dobritzsch, D., Petsalaki, E., Överby, A. K., Jemth, P., Davey, N. E. and Ivarsson, Y. (2023). Large-scale phage-based screening reveals extensive pan-viral mimicry of host short linear motifs. Nat Commun 14: 2409. The first experimental pan RNA viurs analysis of how viruses use motif-based interactions to hijack the host cell. # Citations 39.

Last updated: 2025-12-02

Content Responsible: Hampus Pehrsson Ternström(hampus.persson@scilifelab.uu.se)